Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentsperm head-tail coupling apparatus

CNTLN CCDC42

3.42e-0418322GO:0120212
DomainSH3_1

STAM2 SKAP2 ARHGEF6

2.49e-03164313PF00018
DomainSH3

STAM2 SKAP2 ARHGEF6

5.40e-03216313PS50002
DomainSH3

STAM2 SKAP2 ARHGEF6

5.40e-03216313SM00326
DomainSH3_domain

STAM2 SKAP2 ARHGEF6

5.68e-03220313IPR001452
DomainRAB

RAB8B RAB8A

6.51e-0373312PS51419
Pubmed

Glucocorticoids antagonize estrogens by glucocorticoid receptor-mediated activation of estrogen sulfotransferase.

NR3C1 SULT1E1

8.20e-07232218794126
Pubmed

Rab8 GTPase regulates Klotho-mediated inhibition of cell growth and progression by directly modulating its surface expression in human non-small cell lung cancer.

RAB8B RAB8A

2.46e-06332231707148
Pubmed

A Rab8-specific GDP/GTP exchange factor is involved in actin remodeling and polarized membrane transport.

RAB8B RAB8A

2.46e-06332212221131
Pubmed

Chloroquine-Inducible Par-4 Secretion Is Essential for Tumor Cell Apoptosis and Inhibition of Metastasis.

RAB8B RAB8A

2.46e-06332228076793
Pubmed

Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1.

RAB8B RAB8A

4.92e-06432226471730
Pubmed

Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis.

RAB8B RAB8A

4.92e-06432224213529
Pubmed

The interaction of JRAB/MICAL-L2 with Rab8 and Rab13 coordinates the assembly of tight junctions and adherens junctions.

RAB8B RAB8A

8.19e-06532218094055
Pubmed

GRAF2, WDR44, and MICAL1 mediate Rab8/10/11-dependent export of E-cadherin, MMP14, and CFTR ΔF508.

RAB8B RAB8A

2.94e-05932232344433
Pubmed

Final stages of cytokinesis and midbody ring formation are controlled by BRUCE.

RAB8B RAB8A

5.38e-051232218329369
Pubmed

EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells.

RAB8B RAB8A

6.36e-051332226833786
Pubmed

EHBP1L1, an apicobasal polarity regulator, is critical for nuclear polarization during enucleation of erythroblasts.

RAB8B RAB8A

1.11e-041732237042948
Pubmed

Rab GTPases regulating phagosome maturation are differentially recruited to mycobacterial phagosomes.

RAB8B RAB8A

1.24e-041832221255211
Pubmed

Rab8B GTPase and junction dynamics in the testis.

RAB8B RAB8A

1.24e-041832212639940
Pubmed

Genome-wide association identifies ATOH7 as a major gene determining human optic disc size.

RFTN1 MYPN

1.39e-041932220395239
Pubmed

Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis.

RAB8B RAB8A

2.05e-042332229330353
Pubmed

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

RAB8B RAB8A

5.35e-043732220937701
Pubmed

Mutation of ARHGAP9 in patients with coronary spastic angina.

ARHGAP29 ARHGEF6

5.65e-043832219911011
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

RFTN1 STAM2 PRKCSH SEMA6D

5.82e-0442132436976175
Pubmed

Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

MGAT4D STAM2 CHRNA9 GPR75

6.98e-0444232415815621
Pubmed

Functional dissection of Rab GTPases involved in primary cilium formation.

RAB8B RAB8A

7.23e-044332217646400
GeneFamilyX-linked mental retardation|Angiotensin receptors

ZNF711 ARHGEF6

2.23e-0353242103
GeneFamilyRAB, member RAS oncogene GTPases

RAB8B RAB8A

3.34e-0365242388
CoexpressionGSE13306_TREG_VS_TCONV_SPLEEN_DN

ARHGAP29 SLFN12L STAM2 SEMA6D NFE2L1

4.09e-06199325M3225
CoexpressionAtlasdev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

ZNF711 SEMA6D RAB8B GRK5

4.30e-05135314gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k1_1000
CoexpressionAtlasdev gonad_e11.5_M_ReproVasc_Flk_k-means-cluster#2_top-relative-expression-ranked_500

ZNF711 ARHGAP29 SEMA6D

8.23e-0558313gudmap_dev gonad_e11.5_M_ReproVasc_Flk_k2_500
CoexpressionAtlasdev gonad_e13.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_500

ARHGAP29 CNTLN SEMA6D ITPR2

8.54e-05161314gudmap_dev gonad_e13.5_F_SupCellPrec_Sry_k2_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#1_top-relative-expression-ranked_1000

ARHGAP29 CNTLN SEMA6D ITPR2

9.61e-05166314gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k1_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_1000

ZNF711 ARHGAP29 SEMA6D

1.01e-0462313gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k2_1000
CoexpressionAtlasdev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#2_top-relative-expression-ranked_500

ZNF711 SEMA6D GRK5

1.21e-0466313gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k2_500
CoexpressionAtlasdev gonad_e11.5_F_ReproVasc_Flk_k-means-cluster#4_top-relative-expression-ranked_1000

ARHGAP29 RAB8B GRK5

1.32e-0468313gudmap_dev gonad_e11.5_F_ReproVasc_Flk_k4_1000
CoexpressionAtlasdev gonad_e11.5_F_ReproVasc_Flk_top-relative-expression-ranked_1000

ZNF711 ARHGAP29 SEMA6D SKAP2 RAB8B ARHGEF6 GRK5

1.42e-04817317gudmap_dev gonad_e11.5_F_ReproVasc_Flk_1000
CoexpressionAtlasdev gonad_e12.5_F_DevVasOvary_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

ZNF711 SEMA6D RAB8B GRK5

1.52e-04187314gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_k1_1000
CoexpressionAtlasdev gonad_e13.5_F_DevVascOvary_Flk_top-relative-expression-ranked_1000

ZNF711 ARHGAP29 SEMA6D GNE RAB8B GRK5 ITPR2

1.58e-04831317gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#1_top-relative-expression-ranked_500

ARHGAP29 SEMA6D ITPR2

1.77e-0475313gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k1_500
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#5_top-relative-expression-ranked_1000

ZNF711 ARHGAP29 SEMA6D ITPR2

2.78e-04219314gudmap_developingGonad_e16.5_ovary_1000_k5
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#2_top-relative-expression-ranked_500

ARHGAP29 SEMA6D ITPR2

2.94e-0489313gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k2_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_500

ARHGAP29 SEMA6D ITPR2

3.45e-0494313gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_1000

ARHGAP29 CNTLN SEMA6D ITPR2

4.67e-04251314gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

ZNF711 ARHGAP29 CNTLN SEMA6D GRK5 ITPR2

6.13e-04740316gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#3_top-relative-expression-ranked_1000

ARHGAP29 CNTLN SEMA6D ITPR2

6.14e-04270314gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k3_1000
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_500

ZNF711 ARHGAP29

7.61e-0428312gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_500
CoexpressionAtlasdev gonad_e11.5_F_ReproVasc_Flk_k-means-cluster#1_top-relative-expression-ranked_500

ARHGAP29 SEMA6D

8.17e-0429312gudmap_dev gonad_e11.5_F_ReproVasc_Flk_k1_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

ZNF711 ARHGAP29 CNTLN SEMA6D GRK5 ITPR2

8.24e-04783316gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000

ZNF711 ARHGAP29 CNTLN SEMA6D GRK5 ITPR2

9.04e-04797316gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000

ZNF711 ARHGAP29 CNTLN SEMA6D GRK5 ITPR2

9.04e-04797316gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_1000

ARHGAP29 CNTLN SEMA6D ITPR2

9.21e-04301314gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_1000
CoexpressionAtlasdev gonad_e12.5_F_DevVasOvary_Flk_top-relative-expression-ranked_1000

ZNF711 ARHGAP29 SEMA6D GNE RAB8B GRK5

1.03e-03817316gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_1000
CoexpressionAtlasgudmap_RNAseq_p2_CD2APMEISWT_2500_K4

RFTN1 SLFN12L NR3C1 CCDC42 DTX3 ARHGEF6

1.20e-03842316gudmap_RNAseq_p2_CD2APMEISWT_2500_K4
CoexpressionAtlasdev gonad_e12.5_M_DevVasTestis_Flk_top-relative-expression-ranked_1000

ZNF711 ARHGAP29 SEMA6D GNE RAB8B GRK5

1.24e-03847316gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_1000
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

ARHGAP29 RFTN1 NR3C1 SEMA6D SULT1E1

2.87e-0719832572aad5b2dcd8b0bde58828fa4f8129fe6cb6a21d
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.Fibcd1-Kitl_(CA1_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MGAT4D CHRNA9 CCDC42

9.32e-0657323504d3ba4f7625307f0352e2a402e7c7062a3ea7f
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ANKRD62 RFTN1 SEMA6D GRK5

9.69e-06188324ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

ANKRD62 RFTN1 SEMA6D GRK5

9.89e-06189324d7ed96add29f219183c802895fbff519b627f635
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ANKRD62 RFTN1 SEMA6D GRK5

1.01e-051903244eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ANKRD62 RFTN1 SEMA6D GRK5

1.01e-051903247be4341e2909101d756f14031c21e705eb45e69a
ToppCellIPF-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

ARHGAP29 RFTN1 SEMA6D GRK5

1.10e-051943243892b188f424ffb80f3c75a1b6709a21c1e1601d
ToppCellParenchymal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD62 RFTN1 SEMA6D GRK5

1.16e-0519732441dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD62 RFTN1 SEMA6D GRK5

1.16e-05197324f66945f9007d59d4208849c7fd727f8519713fbc
ToppCellTracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

RFTN1 SLFN12L TTC16 RAB8B

1.24e-05200324893bb7c25ad7c6589a4c7c0364c2ace666e9b4be
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crh_4930553C11Rik_|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

SEMA6D ARHGEF6 MYPN

1.07e-041293236bc85761dea1f97c19bb379a99e4daf85d53201e
ToppCellNS-control-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ZNF711 GRK5 ITPR2

2.26e-041663236d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCellAdult-Immune-natural_killer_cell-D122|Adult / Lineage, Cell type, age group and donor

SLFN12L CHRNA9 TTC16

2.30e-04167323ff1ce3b1a2d91d2ad979f25899db4f4eeb865892
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP29 SEMA6D SULT1E1

2.43e-04170323d9ed257d0938442d0bb280e4c4b0c9b657511b46
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZNF711 ARHGAP29 ZNF35

2.55e-04173323fbc8ed566ea36c39c258dd6b3823c82f5d6eb17f
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RFTN1 SEMA6D GRK5

2.78e-04178323185b44700f06ec58b3c09c80520502166c965fd6
ToppCell10x3'2.3-week_14-16-Lymphocytic_T-T_NK-CD8_T_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SLFN12L TTC16 GPR75

2.82e-041793234e9e0deabf9b09ffcf30fed6d5eae72ce0ef2f1f
ToppCellEndothelial-A-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

ARHGAP29 GRK5 SULT1E1

2.82e-04179323138fd6ba6bdbd0ad01c574168addf720b67a0fea
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

RFTN1 SEMA6D GRK5

2.91e-04181323451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ZNF711 ARHGAP29 SEMA6D

2.91e-041813239cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCellCOVID-19-Fibroblasts-Pericytes|COVID-19 / group, cell type (main and fine annotations)

ANKRD62 SEMA6D GRK5

3.11e-041853234905adaeeffd353e089578e5ea614437dbe794e6
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

RFTN1 SEMA6D GRK5

3.11e-04185323a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCellCOVID-19_Severe-CD8+_T_activated|COVID-19_Severe / Disease condition and Cell class

TTC16 RAB8B RAB8A

3.16e-04186323fc087b79240fe7ada5810d4f4b3c7287eab598ff
ToppCellCOPD-Stromal-Pericyte|Stromal / Disease state, Lineage and Cell class

RFTN1 SEMA6D GRK5

3.21e-04187323406ecd1dabb3ed8d871aef159f7bd1e383434953
ToppCellEndothelial-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

ARHGAP29 GRK5 SULT1E1

3.21e-04187323fd93f3f4b82dae3bf4eef245bfedc2a9e3251b61
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

ANKRD62 RFTN1 GRK5

3.21e-0418732362759efb660179402fb574ce5701c89a2e17bcfe
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

RFTN1 GRK5 SULT1E1

3.21e-04187323a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

ARHGAP29 GRK5 ITPR2

3.31e-0418932375c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

ARHGAP29 GRK5 ITPR2

3.31e-04189323c81787a8c662db5d7814c583dd64562857629e81
ToppCellPND07-28-samps-Endothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ZNF711 ARHGAP29 SEMA6D

3.31e-04189323eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCelltumor_Lung-Fibroblasts-Pericytes|Fibroblasts / Location, Cell class and cell subclass

ARHGAP29 ANKRD62 SEMA6D

3.31e-041893239c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ZNF711 ARHGAP29 SEMA6D

3.31e-04189323d4a25d59d88325d3b20f4287e9b1160c82961a96
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RFTN1 ARHGEF6 ITPR2

3.31e-0418932327e5d706f10a6221f314faf642eede15deab3165
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RFTN1 SLFN12L TTC16

3.36e-04190323d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Immune|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RFTN1 SLFN12L ARHGEF6

3.41e-04191323468b5149d1533f03521844d3cce8633d44eb6ed4
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD62 RFTN1 SEMA6D

3.41e-04191323716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

RFTN1 SEMA6D SKAP2

3.41e-0419132378ad7c555409ce1391bce406bc0f3ef575329ece
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD62 RFTN1 SEMA6D

3.41e-041913231626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCellFetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLFN12L CNTLN SEMA6D

3.46e-0419232372881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RFTN1 ARHGEF6 ITPR2

3.52e-041933231526f51b589a7dc7a28f35f0e788dc38d338d2bc
ToppCellnormal_Lymph_Node-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

RFTN1 NR3C1 RAB8B

3.52e-04193323024d30eb143d8278c0851c3a6c9426226fa3b480
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ZNF711 TTC41P ZNF35

3.57e-04194323b111d10c99d7ff7eb261cd7786cd9d9a549049b1
ToppCellIPF-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

NFE2L1 ITPR2 SULT1E1

3.57e-04194323e8a9005963704286bcc50785bda8d7d63ec001b1
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Neuronal-Cortical_hem|1_mon / Sample Type, Dataset, Time_group, and Cell type.

ARHGAP29 NR3C1 SULT1E1

3.57e-041943236f32422e1c079a2fbf0ab568e6cb8365fd627d9a
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP29 RFTN1 SULT1E1

3.57e-041943237a7406c3b021aeafde423d20290c681c3e8ea0a6
ToppCell11.5-Distal-Mesenchymal-Pericyte|Distal / Age, Tissue, Lineage and Cell class

ARHGAP29 RFTN1 SULT1E1

3.57e-0419432308701590496cf85ff790e54a81493c61177e76ff
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_adventitial_fibro_(9)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RFTN1 GRK5 SULT1E1

3.62e-0419532370387a62f121f8c374dba1aca9ab65cfed6a0b10
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP29 RFTN1 SULT1E1

3.62e-041953239b3fa1d42ec5aa2911f27a99cd8b57714c6bd604
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ANKRD62 RFTN1 SEMA6D

3.68e-04196323c373465e34e2dd581247962d59e0477aae877079
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ANKRD62 RFTN1 SEMA6D

3.68e-041963238b5337ccf74de90e8b89a02ac00671af1de2cfff
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP29 RFTN1 SEMA6D

3.73e-041973236668f0da54f3bf96769275e668cd57e00b8a5ef9
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP29 RFTN1 SEMA6D

3.73e-041973237c275a2ac24a9a4f83fceda93a067e754837102f
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Pericyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARHGAP29 RFTN1 SEMA6D

3.79e-0419832376d46950c11cb4708866db0da54ce00d5c0adab8
ToppCellTracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_activated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RFTN1 CCDC42 RAB8B

3.85e-041993237b3d4c62b11268c7c1599600d8a7b331287cf21a
ToppCellBronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD62 SEMA6D GRK5

3.85e-04199323929f809579368201331d9099d8904b6e3c41797b
ToppCellBronchial-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANKRD62 SEMA6D GRK5

3.85e-04199323854628ce91068093c14bd4d45ba38c41469f3549
ToppCellmedial-mesenchymal-Pericyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANKRD62 RFTN1 SEMA6D

3.90e-04200323bbda454260016be92b539e220ecf7bcbbc6139e4
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ARHGAP29 ANKRD62 GRK5

3.90e-0420032343b76e382b38b9856c07557a75e5b1ce0cee1d9e
ToppCellSepsis-ICU-NoSEP-Lymphocyte-T/NK-CD8+_Tem|ICU-NoSEP / Disease, condition lineage and cell class

SLFN12L TTC16 DTX3

3.90e-04200323c02584afc76216dd8b9985fa27c5cf93712f5745
ToppCelldistal-mesenchymal-Pericyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANKRD62 RFTN1 SEMA6D

3.90e-04200323867935701fac71a3fe01578362da0676f959736c
ToppCellmedial-mesenchymal-Pericyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANKRD62 RFTN1 SEMA6D

3.90e-04200323f36d7cb6345daccebf76997f998e35d959b59452
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

RFTN1 SEMA6D DTX3

3.90e-0420032369edc375d85689300d1dbc1217fedc40063ecdcb
ToppCelldistal-mesenchymal-Pericyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANKRD62 RFTN1 SEMA6D

3.90e-04200323fe31287cfb51d45643bdedbaa5efc03ed87263c6
ToppCellControl_saline-Endothelial-Endothelial-Vein|Control_saline / Treatment groups by lineage, cell group, cell type

SKAP2 NFE2L1 SULT1E1

3.90e-04200323e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCellParenchyma_COVID-19-Stromal-TX-Smooth_muscle-1|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

ARHGAP29 ANKRD62 GRK5

3.90e-0420032378e9a40153d7ba5d9ea6393a37d26fc5c0220867
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ARHGAP29 ANKRD62 GRK5

3.90e-04200323c46e06b4f22d3456e67bc62a9ac198e8041965ad
ToppCelldistal-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANKRD62 RFTN1 SEMA6D

3.90e-042003234ee0b2f56c2652435fa78bf6b3c90cea28df74e0
ToppCellmedial-2-mesenchymal-Pericyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

ANKRD62 RFTN1 SEMA6D

3.90e-042003239820fb4f6efcdfc6de937ef2302a98b48426baa3
DrugRibavirin [36791-04-5]; Up 200; 16.4uM; MCF7; HT_HG-U133A

NR3C1 SEMA6D DTX3 GRK5 GPR75

6.36e-061963156018_UP
DrugBemegride [64-65-3]; Up 200; 25.8uM; MCF7; HT_HG-U133A

NR3C1 RIBC2 GRK5 GPR75 ITPR2

6.85e-061993153389_UP
Drughydrocortisone 17-butyrate 21-propionate

STAM2 NR3C1

3.75e-057312CID000051627
DrugSDDs

STAM2 GNE

6.42e-059312CID000087190
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

ARHGAP29 GNE RAB8B GRK5

1.07e-041833146910_UP
DrugBacampicillin hydrochloride [37661-08-8]; Down 200; 8uM; MCF7; HT_HG-U133A

NR3C1 RIBC2 RAB8B ITPR2

1.34e-041943143273_DN
Drug5211181; Up 200; 12uM; MCF7; HT_HG-U133A_EA

RFTN1 NR3C1 RIBC2 NFE2L1

1.37e-04195314834_UP
DrugAsiaticoside [16830-15-2]; Down 200; 4.2uM; MCF7; HT_HG-U133A

RFTN1 STAM2 NR3C1 RIBC2

1.37e-041953147004_DN
DrugPicotamide monohydrate [80530-63-8]; Up 200; 10.2uM; PC3; HT_HG-U133A

ZNF711 STAM2 CNTLN RIBC2

1.37e-041953147140_UP
DrugSuloctidil [54063-56-8]; Down 200; 11.8uM; MCF7; HT_HG-U133A

NR3C1 RIBC2 SKAP2 GRK5

1.37e-041953145021_DN
DrugGallamine triethiodide [65-29-2]; Up 200; 4.4uM; MCF7; HT_HG-U133A

RFTN1 CHRNA9 ARHGEF6 SULT1E1

1.37e-041953146215_UP
DrugGlafenine hydrochloride [65513-72-6]; Down 200; 9.8uM; MCF7; HT_HG-U133A

STAM2 RIBC2 SKAP2 ITPR2

1.37e-041953147018_DN
DrugAC1NPJ0Q

NR3C1 GRK5 RAB8A

1.39e-0474313CID005159167
DrugIocetamic acid [16034-77-8]; Up 200; 6.6uM; PC3; HT_HG-U133A

ZNF711 STAM2 RIBC2 GRK5

1.40e-041963144600_UP
DrugCP-319743 [172078-87-4]; Down 200; 10uM; MCF7; HT_HG-U133A

STAM2 ZNF35 ARHGEF6 GRK5

1.42e-041973147486_DN
DrugBendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A

SEMA6D RIBC2 DTX3 ITPR2

1.42e-041973143934_DN
DrugCarbimazole [22232-54-8]; Up 200; 21.4uM; MCF7; HT_HG-U133A

NR3C1 ARHGEF6 GRK5 ITPR2

1.42e-041973143299_UP
DrugChloropyramine hydrochloride [6170-42-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A

CNTLN NR3C1 DTX3 ITPR2

1.42e-041973143350_UP
DrugFlorfenicol [73231-34-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A

RFTN1 NR3C1 GNE RAB8B

1.42e-041973145300_DN
DrugAtropine-N-oxide hydrochloride [4574-60-1]; Up 200; 11.8uM; PC3; HT_HG-U133A

CNTLN DTX3 GRK5 ITPR2

1.45e-041983144476_UP
DrugTranylcypromine hydrochloride [1986-47-6]; Up 200; 23.6uM; MCF7; HT_HG-U133A

RFTN1 NR3C1 SEMA6D GNE

1.45e-041983145996_UP
DrugEbselen [60940-34-3]; Down 200; 14.6uM; HL60; HT_HG-U133A

STAM2 CNTLN GPR75 ITPR2

1.48e-041993142717_DN
DrugPhenindione [83-12-5]; Up 200; 18uM; MCF7; HT_HG-U133A

RFTN1 CHRNA9 DTX3 ARHGEF6

1.51e-042003145991_UP
Drugdeoxoestrone

NR3C1 SULT1E1

1.62e-0414312CID000005888
DiseaseDyggve-Melchior-Clausen disease (implicated_via_orthology)

RAB8B RAB8A

5.20e-064282DOID:0111167 (implicated_via_orthology)
DiseaseSmith-McCort dysplasia (implicated_via_orthology)

RAB8B RAB8A

8.67e-065282DOID:0060247 (implicated_via_orthology)
DiseaseMental Retardation, X-Linked Nonsyndromic

ZNF711 ARHGEF6

6.73e-0513282C3501611
DiseaseMental Retardation, X-Linked

ZNF711 ARHGEF6

3.47e-0429282C1136249
DiseaseMental Retardation, X-Linked 1

ZNF711 ARHGEF6

4.23e-0432282C2931498
Diseaserenal cell carcinoma

PRKCSH ITPR2

7.30e-0442282EFO_0000681
Diseaseunipolar depression

SLFN12L PRKCSH CNTLN SEMA6D GRK5 ITPR2

8.00e-041206286EFO_0003761
DiseaseLiver Dysfunction

GRK5 SULT1E1

2.13e-0372282C0086565
DiseaseLiver diseases

GRK5 SULT1E1

2.13e-0372282C0023895
DiseaseS-warfarin measurement

OR4D1 RFTN1

3.82e-0397282EFO_0803323
Diseasevital capacity

NR3C1 SKAP2 ARHGEF6 GRK5 MYPN

5.63e-031236285EFO_0004312
DiseaseLiver Cirrhosis, Experimental

SEMA6D SKAP2 RAB8B SULT1E1

5.83e-03774284C0023893

Protein segments in the cluster

PeptideGeneStartEntry
FKTLMGQCQDLRKRK

ARHGEF6

411

Q15052
RELKQENKRMKQCLE

ARHGEF6

726

Q15052
QIRELKKMKKNRDAC

CNTLN

1301

Q9NXG0
ECRKLEENNKGLMKE

ANKRD62

821

A6NC57
MNKRLKNDLGCQGKN

CHRNA9

396

Q9UGM1
RAMKKANKERELKCQ

CCDC42

106

Q96M95
RGKNKMAAQNCRKRK

NFE2L1

661

Q14494
KMILGNKCDVNDKRQ

RAB8A

116

P61006
RMILGNKCDMNDKRQ

RAB8B

116

Q92930
MGCGLNKLEKRDEKR

RFTN1

1

Q14699
NKKCRNQHQRLLKNM

ITPR2

1196

Q14571
CKEKGRKERESLQQM

PRKCSH

116

P14314
NQALEMKRQGKREKA

FICD

111

Q9BVA6
CLQAGMNLEARKTKK

NR3C1

481

P04150
QNDKIMCILENRKKR

RIBC2

76

Q9H4K1
CKQKTRLRAMGKGNL

GPR75

401

O95800
DAGEDLRNCMKRKKQ

MGAT4D

331

A6NG13
AENALKKAKLLCMQR

ARHGAP29

321

Q52LW3
KELKKAQRQGELMGC

DTX3

91

Q8N9I9
MEKNGNNRKLRVCVA

GNE

1

Q9Y223
KMLLTKDAKQRLGCQ

GRK5

421

P34947
NQDMKAAMRRLGKCL

OR4D1

291

Q15615
VRMNNTLRKDGKKDC

SKAP2

171

O75563
AMARGCFLNAKRNKK

PRAMEF25

121

A6NGN4
CEKGNMLKRQRIKRE

ZNF35

156

P13682
LGENNRKKMKDCQLR

SLFN12L

41

Q6IEE8
RKKMKDCQLRKQQNE

SLFN12L

46

Q6IEE8
LECRKENLMNGVKQL

SULT1E1

81

P49888
ECLNIRKSLFGKKNM

TTC41P

971

Q6P2S7
NGAKDCLKAIMKRVN

STAM2

41

O75886
KMGFCEQRRKQFQKA

TTC16

411

Q8NEE8
CKRGFRQQNELKKHM

ZNF711

681

Q9Y462
RQQDRENCAMKGKHK

SEMA6D

101

Q8NFY4
DGKQISKRNEHCKMR

MYPN

981

Q86TC9