Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	cytoplasmic periphery of the nuclear pore complex	RANBP2 RGPD3	1.37e-04	8	47	2	GO:1990723
GeneOntologyCellularComponent	nuclear pore cytoplasmic filaments	RANBP2 RGPD3	2.20e-04	10	47	2	GO:0044614
GeneOntologyCellularComponent	annulate lamellae	RANBP2 RGPD3	4.43e-04	14	47	2	GO:0005642
GeneOntologyCellularComponent	nuclear pore nuclear basket	RANBP2 RGPD3	7.40e-04	18	47	2	GO:0044615
GeneOntologyCellularComponent	nuclear inclusion body	RANBP2 RGPD3	9.16e-04	20	47	2	GO:0042405
GeneOntologyCellularComponent	SUMO ligase complex	RANBP2 RGPD3	1.01e-03	21	47	2	GO:0106068
Domain	Ran_BP1	RANBP2 RGPD3	4.03e-04	12	47	2	PF00638
Domain	ABC_A	ABCA6 ABCA9	4.03e-04	12	47	2	IPR026082
Domain	RANBD1	RANBP2 RGPD3	4.03e-04	12	47	2	PS50196
Domain	RanBD	RANBP2 RGPD3	4.75e-04	13	47	2	SM00160
Domain	Ran_bind_dom	RANBP2 RGPD3	4.75e-04	13	47	2	IPR000156
Domain	Post-SET_dom	SETDB1 NSD2	7.27e-04	16	47	2	IPR003616
Domain	PostSET	SETDB1 NSD2	7.27e-04	16	47	2	SM00508
Domain	POST_SET	SETDB1 NSD2	7.27e-04	16	47	2	PS50868
Domain	PWWP	PWWP2A NSD2	1.14e-03	20	47	2	SM00293
Domain	PWWP	PWWP2A NSD2	1.52e-03	23	47	2	PF00855
Domain	PWWP_dom	PWWP2A NSD2	1.52e-03	23	47	2	IPR000313
Domain	PWWP	PWWP2A NSD2	1.65e-03	24	47	2	PS50812
Domain	Helicase_C	ATRX DDX43 DHX29	2.47e-03	107	47	3	PF00271
Domain	HELICc	ATRX DDX43 DHX29	2.47e-03	107	47	3	SM00490
Domain	Helicase_C	ATRX DDX43 DHX29	2.53e-03	108	47	3	IPR001650
Domain	HELICASE_CTER	ATRX DDX43 DHX29	2.60e-03	109	47	3	PS51194
Domain	HELICASE_ATP_BIND_1	ATRX DDX43 DHX29	2.60e-03	109	47	3	PS51192
Domain	DEXDc	ATRX DDX43 DHX29	2.60e-03	109	47	3	SM00487
Domain	Helicase_ATP-bd	ATRX DDX43 DHX29	2.67e-03	110	47	3	IPR014001
Domain	SET	SETDB1 NSD2	4.77e-03	41	47	2	PF00856
Domain	SET	SETDB1 NSD2	5.98e-03	46	47	2	SM00317
Domain	Znf_FYVE_PHD	ATRX ZFYVE16 NSD2	6.01e-03	147	47	3	IPR011011
Domain	ABC_tran	ABCA6 ABCA9	6.49e-03	48	47	2	PF00005
Domain	ABC_TRANSPORTER_2	ABCA6 ABCA9	6.49e-03	48	47	2	PS50893
Domain	ABC_TRANSPORTER_1	ABCA6 ABCA9	6.76e-03	49	47	2	PS00211
Domain	SET_dom	SETDB1 NSD2	7.03e-03	50	47	2	IPR001214
Domain	SET	SETDB1 NSD2	7.03e-03	50	47	2	PS50280
Domain	ABC_transporter-like	ABCA6 ABCA9	7.03e-03	50	47	2	IPR003439
Domain	RhoGAP	SYDE2 ARHGAP11B	1.06e-02	62	47	2	SM00324
Domain	RhoGAP	SYDE2 ARHGAP11B	1.10e-02	63	47	2	PF00620
Domain	RHOGAP	SYDE2 ARHGAP11B	1.13e-02	64	47	2	PS50238
Domain	RhoGAP_dom	SYDE2 ARHGAP11B	1.13e-02	64	47	2	IPR000198
Domain	-	SYDE2 ARHGAP11B	1.13e-02	64	47	2	1.10.555.10
Pubmed	The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.	RANBP2 ATRX NSD2 RGPD3 HSPA8	1.44e-07	86	49	5	37253089
Pubmed	NECAP 1 regulates AP-2 interactions to control vesicle size, number, and cargo during clathrin-mediated endocytosis.	AP2B1 FCHO1	1.16e-05	4	49	2	24130457
Pubmed	Evolutionary analysis of a cluster of ATP-binding cassette (ABC) genes.	ABCA6 ABCA9	1.94e-05	5	49	2	12532264
Pubmed	ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment.	SETDB1 ATRX	1.94e-05	5	49	2	27029610
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	RANBP2 LIMA1 OR13D1 GPR19 ATRX AP2B1 NSD2 RGPD3 NEB HSPA8	2.73e-05	1442	49	10	35575683
Pubmed	Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.	RANBP2 RGPD3	4.07e-05	7	49	2	30944974
Pubmed	Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.	RANBP2 RGPD3	4.07e-05	7	49	2	38838144
Pubmed	Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.	RANBP2 RGPD3	4.07e-05	7	49	2	21205196
Pubmed	Endosomal transport of ErbB-2: mechanism for nuclear entry of the cell surface receptor.	RANBP2 AP2B1	4.07e-05	7	49	2	16314522
Pubmed	Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.	RANBP2 RGPD3	4.07e-05	7	49	2	18949001
Pubmed	Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.	RANBP2 RGPD3	4.07e-05	7	49	2	25187515
Pubmed	Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.	RANBP2 RGPD3	4.07e-05	7	49	2	9037092
Pubmed	Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.	RANBP2 RGPD3	4.07e-05	7	49	2	23536549
Pubmed	Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.	RANBP2 RGPD3	4.07e-05	7	49	2	8603673
Pubmed	Retina-specifically expressed novel subtypes of bovine cyclophilin.	RANBP2 RGPD3	4.07e-05	7	49	2	7559465
Pubmed	Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).	RANBP2 RGPD3	4.07e-05	7	49	2	26632511
Pubmed	Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.	RANBP2 RGPD3	4.07e-05	7	49	2	17372272
Pubmed	Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.	RANBP2 RGPD3	4.07e-05	7	49	2	24403063
Pubmed	Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.	RANBP2 RGPD3	4.07e-05	7	49	2	23818861
Pubmed	Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.	RANBP2 RGPD3	4.07e-05	7	49	2	38657106
Pubmed	Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.	RANBP2 RGPD3	4.07e-05	7	49	2	11353387
Pubmed	Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.	RANBP2 RGPD3	4.07e-05	7	49	2	12191015
Pubmed	Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).	RANBP2 RGPD3	4.07e-05	7	49	2	22821000
Pubmed	Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.	RANBP2 RGPD3	4.07e-05	7	49	2	20682751
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	RANBP2 LIMA1 ATRX AP2B1 ZFYVE16 DHX29 HSPA8 NOL8	4.46e-05	934	49	8	33916271
Pubmed	The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.	RANBP2 RGPD3	5.42e-05	8	49	2	22262462
Pubmed	The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.	RANBP2 RGPD3	5.42e-05	8	49	2	21670213
Pubmed	Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.	RANBP2 RGPD3	5.42e-05	8	49	2	28745977
Pubmed	Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.	RANBP2 RGPD3	5.42e-05	8	49	2	27412403
Pubmed	Mice lacking Ran binding protein 1 are viable and show male infertility.	RANBP2 RGPD3	5.42e-05	8	49	2	21310149
Pubmed	A human MAP kinase interactome.	SETDB1 RANBP2 AP2B1 PAK1 PRKAR1B NEB	6.07e-05	486	49	6	20936779
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	SETDB1 RANBP2 RGPD3 HSPA8	6.54e-05	153	49	4	26365490
Pubmed	The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.	RANBP2 RGPD3	6.96e-05	9	49	2	9733766
Pubmed	Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.	RANBP2 RGPD3	6.96e-05	9	49	2	28100513
Pubmed	Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.	RANBP2 RGPD3	6.96e-05	9	49	2	18394993
Pubmed	Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.	RANBP2 RGPD3	6.96e-05	9	49	2	28877029
Pubmed	The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.	RANBP2 RGPD3	6.96e-05	9	49	2	11553612
Pubmed	Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.	RANBP2 RGPD3	6.96e-05	9	49	2	17887960
Pubmed	The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.	RANBP2 RGPD3	6.96e-05	9	49	2	10601307
Pubmed	Structural and mechanistic insights into ATRX-dependent and -independent functions of the histone chaperone DAXX.	SETDB1 ATRX	6.96e-05	9	49	2	29084956
Pubmed	The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.	RANBP2 RGPD3	8.69e-05	10	49	2	27160050
Pubmed	The human ATP-binding cassette (ABC) transporter superfamily.	ABCA6 ABCA9	8.69e-05	10	49	2	11435397
Pubmed	Parkin ubiquitinates and promotes the degradation of RanBP2.	RANBP2 RGPD3	8.69e-05	10	49	2	16332688
Pubmed	Abi1 is essential for the formation and activation of a WAVE2 signalling complex.	NEB HSPA8	8.69e-05	10	49	2	15048123
Pubmed	Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.	RANBP2 RGPD3	8.69e-05	10	49	2	8857542
Pubmed	Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.	RANBP2 RGPD3	8.69e-05	10	49	2	21859863
Pubmed	An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.	RANBP2 RGPD3	1.06e-04	11	49	2	35771867
Pubmed	RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.	RANBP2 RGPD3	1.06e-04	11	49	2	17069463
Pubmed	T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.	RANBP2 RGPD3	1.06e-04	11	49	2	34110283
Pubmed	Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.	RANBP2 RGPD3	1.50e-04	13	49	2	31427429
Pubmed	Role of the AP2 beta-appendage hub in recruiting partners for clathrin-coated vesicle assembly.	AP2B1 HSPA8	1.75e-04	14	49	2	16903783
Pubmed	Association of dysfunctional synapse defective 1 (SYDE1) with restricted fetal growth - SYDE1 regulates placental cell migration and invasion.	SYDE2 PAK1	2.02e-04	15	49	2	27917469
Pubmed	Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.	RANBP2 RGPD3	2.02e-04	15	49	2	14697343
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	RANBP2 ATRX AP2B1 NOL8	2.73e-04	222	49	4	37071664
Pubmed	Scanning the human proteome for calmodulin-binding proteins.	RANBP2 ATRX NEB	3.02e-04	92	49	3	15840729
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RANBP2 LIMA1 AP2B1 RGPD3 PAK1 PRKAR1B HSPA8	3.80e-04	963	49	7	28671696
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	RANBP2 LIMA1 RGPD3 PAK1 HSPA8	3.98e-04	444	49	5	34795231
Pubmed	Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.	RANBP2 RGPD3	4.41e-04	22	49	2	27717094
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCA6 ABCA9	4.41e-04	22	49	2	8894702
Pubmed	Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.	SETDB1 ATRX HSPA8	4.58e-04	106	49	3	19394292
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	RANBP2 TUT4 SBDS DHX29 GEN1 NOL8	5.21e-04	724	49	6	36232890
Pubmed	UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.	RANBP2 LIMA1 ZFYVE16 HSPA8	5.48e-04	267	49	4	33417871
Pubmed	Human immunodeficiency virus (HIV) type-1, HIV-2 and simian immunodeficiency virus Nef proteins.	AP2B1 PAK1	5.71e-04	25	49	2	20594957
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	RANBP2 LIMA1 HSPA8 NOL8	5.80e-04	271	49	4	32433965
Pubmed	Structure--function relationships in HIV-1 Nef.	AP2B1 PAK1	6.67e-04	27	49	2	11463741
Pubmed	Phosphoproteomics screen reveals akt isoform-specific signals linking RNA processing to lung cancer.	ATRX HSPA8	7.18e-04	28	49	2	24462114
Pubmed	Novel interactors and a role for supervillin in early cytokinesis.	LIMA1 ATRX	7.18e-04	28	49	2	20309963
Pubmed	Protein array based interactome analysis of amyloid-β indicates an inhibition of protein translation.	CCDC60 NSD2 CCDC190 DDX43	9.01e-04	305	49	4	21244100
Pubmed	Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.	RANBP2 RGPD3 HSPA8	9.25e-04	135	49	3	31077711
Pubmed	Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking.	LIMA1 HSPA8	1.12e-03	35	49	2	22337587
Pubmed	Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.	LIMA1 AP2B1 ZFYVE16 HSPA8	1.16e-03	327	49	4	15592455
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	LIMA1 AP2B1 SBDS PRKAR1B DHX29 HSPA8	1.17e-03	847	49	6	35235311
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	NSD2 RGPD3 NEMF DHX29	1.23e-03	332	49	4	25693804
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	SETDB1 RANBP2 ATRX HSPA8	1.23e-03	332	49	4	32786267
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	CCDC60 LIMA1 AP2B1 HSPA8	1.25e-03	333	49	4	32665550
Pubmed	Peering through the pore: nuclear pore complex structure, assembly, and function.	RANBP2 RGPD3	1.32e-03	38	49	2	12791264
Pubmed	Linking functions: an additional role for an intrinsically disordered linker domain in the transcriptional coactivator CBP.	SETDB1 ATRX	1.32e-03	38	49	2	28680062
Pubmed	WDFY4 is required for cross-presentation in response to viral and tumor antigens.	LIMA1 AP2B1 HSPA8	1.40e-03	156	49	3	30409884
GeneFamily	ATP binding cassette subfamily A	ABCA6 ABCA9	2.73e-04	14	32	2	805
GeneFamily	PWWP domain containing	PWWP2A NSD2	6.86e-04	22	32	2	1147
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	SETDB1 NSD2	1.64e-03	34	32	2	487
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	RANBP2 TUT4 CCDC66 ATRX SBDS NEMF GEN1	5.14e-06	311	47	7	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	RANBP2 TUT4 CCDC66 ATRX SBDS NEMF FUT9 PAK1 GEN1 NOL8 JAM2	7.88e-06	989	47	11	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	RANBP2 CCDC66 ATRX SBDS NEMF FUT9 PAK1 GEN1 NOL8 JAM2	1.11e-05	831	47	10	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	RANBP2 CCDC66 NEMF FUT9 PAK1 ANKRD12 NEB NOL8 JAM2	1.13e-05	654	47	9	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K5
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	CFAP54 TUT4 CCDC66 GPR19 ATRX NSD2 FUT9 PAK1 PRKAR1B GEN1 NOL8	1.51e-05	1060	47	11	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500	CFAP54 TUT4 CCDC66 GPR19 ATRX NSD2 FUT9 PAK1 PRKAR1B GEN1 NOL8 JAM2	4.27e-05	1414	47	12	facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2	RANBP2 NEMF FUT9 PAK1 NOL8 JAM2	8.17e-05	328	47	6	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#5	RANBP2 FUT9 GEN1 NOL8 JAM2	8.61e-05	204	47	5	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000_K5
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5	RANBP2 CCDC66 NEMF NOL8 JAM2	1.57e-04	232	47	5	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	TUT4 CCDC66 ATRX NSD2 NEMF RIBC1 FUT9 PAK1 GEN1 NOL8 JAM2	2.70e-04	1459	47	11	facebase_RNAseq_e10.5_Emin_LatNas_2500
ToppCell	10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-ILC_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	RANBP2 SYDE2 GRAMD2B CCDC168 NEB	1.93e-06	187	49	5	f31d865ce2a21bdf64dbe29ee3e4505ab482604a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CFAP54 CCDC66 FCHO1 ANKS3	2.81e-05	159	49	4	b9d34b9ed8db798f5ea93c44b469cae499403cb8
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FUT9 PAK1 DDX43 RGS10	2.95e-05	161	49	4	afc719ffa53ab34c5628da47936da1f731dceab1
ToppCell	droplet-Lung-nan-3m-Myeloid-Interstitial_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAK1 PRKAR1B ABCA9 RGS10	2.95e-05	161	49	4	f1d3287d9cb4e0eec99b3509f5dc4b87ae8c8cc9
ToppCell	droplet-Lung-nan-3m-Myeloid-lung_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PAK1 PRKAR1B ABCA9 RGS10	2.95e-05	161	49	4	110cc7122e3c9f105a11d811d77c8a8852b9de6c
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FUT9 PAK1 DDX43 RGS10	3.17e-05	164	49	4	90404b3b6b6a9b88a75cba09baa94c718e577c44
ToppCell	E18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFAP54 SLITRK6 NEB ANKS3	3.57e-05	169	49	4	16c52a0f6d96ecc1832922fce9b39691849f0d73
ToppCell	droplet-Spleen-nan-24m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMA1 PAK1 PRKAR1B ITGAD	3.73e-05	171	49	4	35acc5c3e36bc605603c0d45375f2cf3c3e9d4cd
ToppCell	Healthy_donor-Treg\|World / disease group, cell group and cell class (v2)	CCDC66 RGPD3 ANKRD12 CCDC141	4.00e-05	174	49	4	dc3b06420b0ad9c7060571e7bf5714e028d598bf
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Myeloid / Condition, Lineage and Cell class	ABCA6 SYDE2 ITGAD ABCA9	4.27e-05	177	49	4	470f54fe2b21c7350ea471e02039461a3808f700
ToppCell	droplet-Spleen-SPLEEN-30m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LIMA1 PAK1 PRKAR1B ITGAD	4.37e-05	178	49	4	6c1b5087581ca8cea976d89ea6f34088c8fc3668
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-T_cells-Treg\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	INAFM2 RGPD3 ANKRD12 CCDC141	4.37e-05	178	49	4	e37142a84d9713ff1571ce9f976842bf5c17c86f
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 ATRX IGLL1 ABCA9	4.76e-05	182	49	4	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	Ciliated_cells-B-Donor_04\|World / lung cells shred on cell class, cell subclass, sample id	CCDC60 CFAP54 RIBC1 SLITRK6	4.76e-05	182	49	4	e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ABCA6 NEB CCDC141 GEN1	4.86e-05	183	49	4	01664fce6b70a02c9d39d747b6a6aabc86d57bc2
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 ATRX IGLL1 ABCA9	5.07e-05	185	49	4	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-Tregs\|bone_marrow / Manually curated celltypes from each tissue	ANKRD12 CCDC141 HSPA8 RGS10	5.29e-05	187	49	4	bda716a64262325e6e68b281caf131f1840fd298
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-Tregs\|lymph-node_spleen / Manually curated celltypes from each tissue	LIMA1 ANKRD12 CCDC141 HSPA8	5.86e-05	192	49	4	04bd6e135733570e877af9460f87379ed0a5c5f8
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-Tregs\|lymph-node_spleen / Manually curated celltypes from each tissue	SBDS ANKRD12 CCDC141 HSPA8	5.86e-05	192	49	4	91a4d06e8d1d1fe2ce5f72668108513bd2a72c4d
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 ATRX NSD2 IGLL1	6.10e-05	194	49	4	8ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell	Healthy-B_intermediate\|Healthy / disease group, cell group and cell class	ABCA6 NEB CCDC141 ABCA9	6.10e-05	194	49	4	aabee48bf689367edae2079b4b90d253715f1097
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TUT4 CCDC66 ATRX ANKRD12	6.22e-05	195	49	4	ed5f772c82d4dfd1c8735224446ec9feae3fb8c2
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATRX ABCA6 NEB ABCA9	6.22e-05	195	49	4	5c86fddd6d0530beecf45ea5ba6b823123847696
ToppCell	Healthy-B_intermediate\|World / disease group, cell group and cell class	ABCA6 NEB CCDC141 ABCA9	6.22e-05	195	49	4	9de79e0bdd9063ae65e5edb89cc3fe6f9a8173bc
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	ATRX NEMF ANKRD12 NOL8	6.47e-05	197	49	4	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	systemic_lupus_erythematosus-flare\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	TUT4 ATRX ANKRD12 HSPA8	6.60e-05	198	49	4	4c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCell	mild-CD4+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYDE2 ANKRD12 CCDC141 RGS10	6.73e-05	199	49	4	3e4baaf4ee23f257d821194468102c00a8ad2f21
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	LIMA1 ATRX ANKRD12 DHX29	6.73e-05	199	49	4	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CCDC60 CFAP54 CCDC190 RIBC1	6.86e-05	200	49	4	85c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CCDC60 CFAP54 CCDC190 RIBC1	6.86e-05	200	49	4	12bc7d95c4166d12487081a76d210b7abe5991b0
ToppCell	MS-Multiple_Sclerosis-Lymphocyte-T/NK-Treg\|Multiple_Sclerosis / Disease, condition lineage and cell class	CCDC66 ANKRD12 CCDC141 HSPA8	6.86e-05	200	49	4	8702758a62fa923c2e9012c0aa8b3b492a44f8fb
Computational	Genes upregulated in subsets of cells of a given type within various tumors	ATRX ANKRD12 NEB	1.91e-04	49	25	3	GAVISH_3CA_MALIGNANT_METAPROGRAM_41_UNASSIGNED
Disease	melanoma (is_marker_for)	SETDB1 ATRX	1.11e-03	33	44	2	DOID:1909 (is_marker_for)
Disease	right ventricular systolic volume measurement	CCDC141 RGS10	1.25e-03	35	44	2	EFO_0021815
Disease	glucose-dependent insulinotropic peptide measurement	SETDB1 CCDC141	2.85e-03	53	44	2	EFO_0008464
Disease	schizophrenia, sex interaction measurement	ABCA6 ABCA9	3.64e-03	60	44	2	EFO_0008343, MONDO_0005090
Disease	MYELODYSPLASTIC SYNDROME	ATRX SBDS	4.52e-03	67	44	2	C3463824

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSSVKETSANKFEMY	CFAP54	2686	Q96N23
MTDSKYFTTNKKGEI	AP2B1	1	P63010
AMSSIGDYKKKAHSQ	ABCA9	1041	Q8IUA7
NAYTITTSSRMAKKN	GPR19	356	Q15760
ITMGSISDYKKNAKS	ABCA6	1031	Q8N139
MEKKNKQSDNSEYSK	ANKRD12	931	Q6UB98
TKENKYHESSQMSSL	DHX29	951	Q7Z478
NKSNSAYKEMQTTLK	CCDC60	331	Q8IWA6
EKLFSSQYGKMANKA	RANBP2	1976	P49792
EKMSSNAEKKGVYQT	ARHGAP11B	211	Q3KRB8
KEIYMTFLSSKASSQ	RGS10	91	O43665
TYSKAMAKLSKLASN	FCHO1	46	O14526
MAKYQAAVSKQSSST	LIMA1	271	Q9UHB6
KAEDYMKTTSNFSGK	NEMF	231	O60524
SVLKMKNFFSTKTDY	FUT9	46	Q9Y231
QQAETMKKKFSSYLG	CCDC190	61	Q86UF4
LNKYESMSSNKDSKR	FAM214A	696	Q32MH5
SYKAMEAASSLKSQA	NSD2	571	O96028
KATTMSENDFKHTKS	JAM2	281	P57087
NSTEFSQMEKSTKKT	NOL8	396	Q76FK4
STKYFNFATSDEKKM	ITGAD	931	Q13349
YNSKKTSNSQKYMSF	PAK1	131	Q13153
TSNSQKYMSFTDKSA	PAK1	136	Q13153
EKLFSSQYGKMANKA	RGPD3	1001	A6NKT7
AKKLIETTANMNSSY	ATRX	356	P46100
ETTANMNSSYVKFLK	ATRX	361	P46100
EMTTPSKQSNNKYAA	IGLL1	161	P15814
MEKVSNKTSDSFLNY	CCDC141	961	Q6ZP82
MSKTGTKITFYEDKN	CRYGS	1	P22914
KMNTYMNSTTSKKDT	CCDC66	596	A2RUB6
SSARKQAKSYMKTKN	ANKS3	381	Q6ZW76
GKAKYTTQRMKHSSQ	GEN1	811	Q17RS7
DYKTMTALAKAISKN	PRKAR1B	121	P31321
SSSQKQNNKTEMYDK	KIAA1210	496	Q9ULL0
YVKFQMEQISSGSSK	CCDC168	936	Q8NDH2
ERKKSSSSSQYKANM	GRAMD2B	96	Q96HH9
AMKDIHYSVKTNKST	SBDS	136	Q9Y3A5
KNFYKESTATSAMSK	DDX43	196	Q9NXZ2
VSSKNSLESYAFNMK	HSPA8	536	P11142
TYTGDKKAKMAAKTN	INAFM2	16	P0DMQ5
YMKPKSKNTNTSDEI	OR13D1	291	Q8NGV5
TSVSSQQSYQKKNSM	SYDE2	596	Q5VT97
QQSYQKKNSMSSKYS	SYDE2	601	Q5VT97
VYMTLNQKKSDSSSA	PWWP2A	566	Q96N64
TGSNMKYKTTNQSTE	SLITRK6	731	Q9H5Y7
KKFASNLSYSMEAEK	OVCH1	1101	Q7RTY7
LMKKDYSTSKFNPSQ	SLC26A3	721	P40879
MPKSSYSTDQNKVVS	OR5P3	261	Q8WZ94
KFMDAVNKKSSSQDL	SETDB1	166	Q15047
YKNMKRSSSQMSLDT	UHRF1BP1L	1101	A0JNW5
MYNIKQSTDTKEAAA	RIBC1	1	Q8N443
NSVKAEKASSYQMKS	TUT4	136	Q5TAX3
KKYSDVMKVLNSSNE	ZFYVE16	1261	Q7Z3T8
KANTKNTSDVMYKKD	NEB	586	P20929
AAKANTKNTSDVMYK	NEB	831	P20929