Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhigh-affinity IgG receptor activity

FCGR1A FCGR1BP

6.22e-0521582GO:0019771
GeneOntologyMolecularFunctionleukotriene receptor binding

FCGR1A FCGR1BP

6.22e-0521582GO:0031774
GeneOntologyBiologicalProcessnegative regulation of ceramide biosynthetic process

ORMDL1 ORMDL3 ORMDL2

4.04e-0651543GO:1900060
GeneOntologyBiologicalProcessintracellular sphingolipid homeostasis

ORMDL1 ORMDL3 ORMDL2

8.03e-0661543GO:0090156
GeneOntologyBiologicalProcessnegative regulation of sphingolipid biosynthetic process

ORMDL1 ORMDL3 ORMDL2

1.40e-0571543GO:0090155
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous antigen

HLA-DOA HLA-DQA2 CD1D FCGR1A FCGR1BP

7.24e-05581545GO:0019884
GeneOntologyCellularComponentserine palmitoyltransferase complex

ORMDL1 ORMDL3 ORMDL2

2.31e-0581583GO:0017059
GeneOntologyCellularComponentpalmitoyltransferase complex

ORMDL1 ORMDL3 ORMDL2

6.69e-05111583GO:0002178
GeneOntologyCellularComponentendosome membrane

ZDHHC11B WASHC4 HLA-DOA HLA-DQA2 TMEM63B ECE1 ZDHHC1 ATP13A2 CD1D FCGR1A FCGR1BP PLEKHM2 TMEM30A ZDHHC11

1.98e-0460215814GO:0010008
GeneOntologyCellularComponentendoplasmic reticulum membrane

RHBDD1 CYP2C18 AUP1 HLA-DQA2 GRIN2C GRIN2D PAPPA-AS1 PIGV ZDHHC1 CD1D ORMDL1 ORMDL3 DST MOGS ORMDL2 ALG9 SRL SELENOI TMEM41B ZDHHC11 ATP2A2 DGAT1

2.98e-04129315822GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

RHBDD1 CYP2C18 AUP1 HLA-DQA2 GRIN2C GRIN2D PAPPA-AS1 PIGV ZDHHC1 CD1D ORMDL1 ORMDL3 DST MOGS ORMDL2 ALG9 SRL SELENOI TMEM41B ZDHHC11 ATP2A2 DGAT1

3.17e-04129915822GO:0098827
GeneOntologyCellularComponentFACT complex

MMS22L SUPT16H

3.37e-0441582GO:0035101
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

RHBDD1 CYP2C18 AUP1 HLA-DQA2 GRIN2C GRIN2D PAPPA-AS1 PIGV ZDHHC1 CD1D ORMDL1 ORMDL3 DST MOGS ORMDL2 ALG9 SRL SELENOI TMEM41B ZDHHC11 ATP2A2 DGAT1

4.25e-04132715822GO:0042175
GeneOntologyCellularComponentexternal side of plasma membrane

HLA-DQA2 ITGA4 GFRA4 ECE1 ITGAE CD1D FCGR1A FCGR1BP SLAMF7 IL6ST EPHA5 CD276

6.00e-0451915812GO:0009897
GeneOntologyCellularComponentspecific granule membrane

UBR4 ORMDL3 CD47 TMEM30A DGAT1

6.38e-04911585GO:0035579
MousePhenoabnormal acute inflammation

RHBDD1 ZDHHC11B PROCR FOS SBSN LGALS3BP CD1D ORMDL3 FCGR1A FCGR1BP ZDHHC11 IL6ST CD276

1.41e-0535712213MP:0002498
MousePhenoabnormal antigen presentation

HLA-DOA HLA-DQA2 CD1D FCGR1A FCGR1BP IL6ST

3.81e-05721226MP:0001835
DomainIg-like_fold

FNDC3B SEMA4B EPHA6 HLA-DOA HLA-DQA2 DCC TMEM25 IGSF10 CD1D HMCN1 FCGR1A FCGR1BP ICAM5 CD101 CD47 ROS1 SIGLEC11 SLAMF7 PLXNA1 IL6ST EPHA5 CD276

7.29e-0870615322IPR013783
Domain-

FNDC3B EPHA6 HLA-DOA HLA-DQA2 DCC TMEM25 IGSF10 CD1D HMCN1 FCGR1A FCGR1BP ICAM5 CD101 CD47 ROS1 SIGLEC11 SLAMF7 PLXNA1 IL6ST EPHA5 CD276

1.13e-07663153212.60.40.10
DomainORMDL

ORMDL1 ORMDL3 ORMDL2

5.39e-0731533IPR007203
DomainORMDL

ORMDL1 ORMDL3 ORMDL2

5.39e-0731533PF04061
DomainIG_LIKE

HLA-DOA HLA-DQA2 DCC TMEM25 IGSF10 CD1D HMCN1 FCGR1A FCGR1BP ICAM5 CD101 CD47 SIGLEC11 SLAMF7 CD276

1.28e-0549115315PS50835
DomainIg-like_dom

HLA-DOA HLA-DQA2 DCC TMEM25 IGSF10 CD1D HMCN1 FCGR1A FCGR1BP ICAM5 CD101 CD47 SIGLEC11 SLAMF7 CD276

1.70e-0550315315IPR007110
DomainGamma_tubulin

TUBG2 TUBG1

6.67e-0521532IPR002454
DomainMHC_I/II-like_Ag-recog

HLA-DOA HLA-DQA2 PROCR CD1D

2.57e-04381534IPR011162
DomainFumarylacetoacetase_C-rel

FAHD2B FAHD2A

3.96e-0441532IPR011234
DomainFAA_hydrolase

FAHD2B FAHD2A

3.96e-0441532PF01557
Domain-

FAHD2B FAHD2A

3.96e-04415323.90.850.10
DomainVWFA

CPNE9 ITGAE CPNE5 MDN1 HMCN1

5.68e-04821535PS50234
DomainVWA

CPNE9 ITGAE CPNE5 MDN1 HMCN1

6.34e-04841535SM00327
DomainC1-set_C

HLA-DOA HLA-DQA2

6.56e-0451532PF16196
DomainMHC_II_alpha

HLA-DOA HLA-DQA2

6.56e-0451532SM00920
DomainC1-set_C

HLA-DOA HLA-DQA2

6.56e-0451532IPR032431
DomainIGc2

DCC IGSF10 HMCN1 FCGR1A FCGR1BP ICAM5 SIGLEC11 CD276

7.22e-042351538SM00408
DomainIg_sub2

DCC IGSF10 HMCN1 FCGR1A FCGR1BP ICAM5 SIGLEC11 CD276

7.22e-042351538IPR003598
DomainM10A_MMP

MMP1 MMP8 MMP26

8.46e-04231533IPR033739
DomainPept_M10A

MMP1 MMP8 MMP26

8.46e-04231533IPR021190
DomainPeptidase_M10

MMP1 MMP8 MMP26

9.62e-04241533PF00413
DomainBRK

CHD8 CHD6

9.79e-0461532SM00592
DomainZF_BED

ZBED5 ZBED6

9.79e-0461532PS50808
Domainzf-BED

ZBED5 ZBED6

9.79e-0461532PF02892
DomainBRK_domain

CHD8 CHD6

9.79e-0461532IPR006576
DomainMHC_II_alpha

HLA-DOA HLA-DQA2

9.79e-0461532PF00993
DomainMHC_I_3

PROCR CD1D

9.79e-0461532PF16497
DomainBRK

CHD8 CHD6

9.79e-0461532PF07533
DomainIGc1

HLA-DOA HLA-DQA2 CD1D CD276

1.14e-03561534SM00407
DomainIg_C1-set

HLA-DOA HLA-DQA2 CD1D CD276

1.30e-03581534IPR003597
DomainVWF_A

CPNE9 ITGAE CPNE5 MDN1 HMCN1

1.33e-03991535IPR002035
DomainMHC_II_a_N

HLA-DOA HLA-DQA2

1.36e-0371532IPR001003
DomainPeptidase_Metallo

MMP1 MMP8 MMP26

1.68e-03291533IPR006026
DomainZnMc

MMP1 MMP8 MMP26

1.68e-03291533SM00235
DomainSemap_dom

SEMA4F SEMA4B PLXNA1

2.05e-03311533IPR001627
DomainSEMA

SEMA4F SEMA4B PLXNA1

2.05e-03311533PS51004
DomainSema

SEMA4F SEMA4B PLXNA1

2.05e-03311533SM00630
DomainSema

SEMA4F SEMA4B PLXNA1

2.05e-03311533PF01403
Domainfn3

FNDC3B EPHA6 DCC ROS1 IL6ST EPHA5

2.20e-031621536PF00041
DomainPlexin_repeat

SEMA4F SEMA4B PLXNA1

2.25e-03321533IPR002165
DomainPSI

SEMA4F SEMA4B PLXNA1

2.25e-03321533PF01437
DomainCopine

CPNE9 CPNE5

2.31e-0391532PF07002
DomainCopine

CPNE9 CPNE5

2.31e-0391532IPR010734
DomainIG

DCC IGSF10 HMCN1 FCGR1A FCGR1BP ICAM5 CD101 SIGLEC11 SLAMF7 CD276

2.50e-0342115310SM00409
DomainIg_sub

DCC IGSF10 HMCN1 FCGR1A FCGR1BP ICAM5 CD101 SIGLEC11 SLAMF7 CD276

2.50e-0342115310IPR003599
DomainAnoctamin

ANO8 ANO7

2.87e-03101532PF04547
DomainAnoctamin

ANO8 ANO7

2.87e-03101532IPR007632
DomainDNA/RNA_helicase_DEAH_CS

DHX37 CHD8 CHD6

2.91e-03351533IPR002464
DomainIGv

IGSF10 HMCN1 CD101 CD276

3.35e-03751534SM00406
DomainIntegrin_alpha

ITGA4 ITGAE

3.49e-03111532PF00357
DomainDEAH_ATP_HELICASE

DHX37 CHD8 CHD6

3.69e-03381533PS00690
DomainZnf_BED

ZBED5 ZBED6

4.17e-03121532IPR003656
DomainFN3

FNDC3B EPHA6 DCC ROS1 IL6ST EPHA5

4.23e-031851536SM00060
Domain-

ECE1 MMP1 MMP8 MMP26

4.42e-038115343.40.390.10
DomainMetalloPept_cat_dom

ECE1 MMP1 MMP8 MMP26

4.42e-03811534IPR024079
DomainCYSTEINE_SWITCH

MMP1 MMP8 MMP26

4.57e-03411533PS00546
DomainC2-set_2

TMEM25 SIGLEC11 CD276

4.57e-03411533PF08205
DomainCD80_C2-set

TMEM25 SIGLEC11 CD276

4.57e-03411533IPR013162
DomainIg_I-set

DCC IGSF10 HMCN1 ICAM5 CD101 SIGLEC11

4.81e-031901536IPR013098
DomainI-set

DCC IGSF10 HMCN1 ICAM5 CD101 SIGLEC11

4.81e-031901536PF07679
Domainig

HMCN1 FCGR1A FCGR1BP ICAM5 SIGLEC11 CD276

4.81e-031901536PF00047
DomainImmunoglobulin

HMCN1 FCGR1A FCGR1BP ICAM5 SIGLEC11 CD276

4.81e-031901536IPR013151
DomainPept_M10_metallopeptidase

MMP1 MMP8 MMP26

5.23e-03431533IPR001818
DomainPSI

SEMA4F SEMA4B PLXNA1

5.58e-03441533IPR016201
DomainRECEPTOR_TYR_KIN_V_2

EPHA6 EPHA5

5.69e-03141532PS00791
DomainRECEPTOR_TYR_KIN_V_1

EPHA6 EPHA5

5.69e-03141532PS00790
DomainMHC_II_a/b_N

HLA-DOA HLA-DQA2

5.69e-03141532IPR014745
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH12

5.69e-03141532IPR024317
DomainTyr_kinase_rcpt_V_CS

EPHA6 EPHA5

5.69e-03141532IPR001426
DomainATPase_dyneun-rel_AAA

DNAH12 MDN1

5.69e-03141532IPR011704
DomainEphA2_TM

EPHA6 EPHA5

5.69e-03141532PF14575
DomainEphrin_rcpt_lig-bd_dom

EPHA6 EPHA5

5.69e-03141532IPR001090
DomainEph_TM

EPHA6 EPHA5

5.69e-03141532IPR027936
DomainEPH_lbd

EPHA6 EPHA5

5.69e-03141532SM00615
DomainEphrin_lbd

EPHA6 EPHA5

5.69e-03141532PF01404
DomainAAA_8

DNAH14 DNAH12

5.69e-03141532PF12780
Domain-

HLA-DOA HLA-DQA2

5.69e-031415323.10.320.10
DomainTyr_kinase_ephrin_rcpt

EPHA6 EPHA5

5.69e-03141532IPR016257
DomainEPH_LBD

EPHA6 EPHA5

5.69e-03141532PS51550
DomainAAA_5

DNAH12 MDN1

5.69e-03141532PF07728
DomainFN3

FNDC3B EPHA6 DCC ROS1 IL6ST EPHA5

6.01e-031991536PS50853
DomainIg_V-set

IGSF10 HMCN1 CD101 SIGLEC11 SLAMF7 CD276

6.01e-031991536IPR013106
DomainPSI

SEMA4F SEMA4B PLXNA1

6.32e-03461533SM00423
DomainDHC_fam

DNAH14 DNAH12

6.53e-03151532IPR026983
DomainDynein_heavy

DNAH14 DNAH12

6.53e-03151532PF03028
DomainPept_M10A_Zn_BS

MMP1 MMP8

6.53e-03151532IPR021158
DomainDynein_heavy_dom

DNAH14 DNAH12

6.53e-03151532IPR004273
DomainIntegrin_alpha_C_CS

ITGA4 ITGAE

7.42e-03161532IPR018184
DomainFN3_dom

FNDC3B EPHA6 DCC ROS1 IL6ST EPHA5

7.57e-032091536IPR003961
Pubmed

ORMDL proteins are a conserved new family of endoplasmic reticulum membrane proteins.

ORMDL1 ORMDL3 ORMDL2

9.74e-083161312093374
Pubmed

Simultaneous reduction of all ORMDL proteins decreases the threshold of mast cell activation.

ORMDL1 ORMDL3 ORMDL2

9.74e-083161337316542
Pubmed

Expression of the ORMDLS, modulators of serine palmitoyltransferase, is regulated by sphingolipids in mammalian cells.

ORMDL1 ORMDL3 ORMDL2

9.74e-083161325395622
Pubmed

Mammalian ORMDL proteins mediate the feedback response in ceramide biosynthesis.

ORMDL1 ORMDL3 ORMDL2

9.74e-083161323066021
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

RHBDD1 SEMA4B PROCR GNPTAB ECE1 LGALS3BP IGSF10 MOGS ALG9 CD47 CPSF1 TMEM30A ITM2C SELENOI TMEM41B TMEM231 ATP2A2 PLXNA1 IL6ST DGAT1 CD276

1.89e-0712011612135696571
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SEMA4F SEMA4B MTG2 NICN1 UBR4 KDM3B CHD8 GRIN2D ECE1 ATP13A2 TUBG1 ANO8 DACT1 DST MDN1 PLEKHM2 CPSF1 LRRC14 PLXNA1 CD276

2.20e-0711051612035748872
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

SEMA4F UBR4 PIDD1 ITGAE TMEM132B DNAH14 TMCO4 IGSF10 FREM2 DST MDN1 MOGS CPSF1 CHD6 ARHGAP20 MTMR9

3.61e-077361611629676528
Pubmed

Orm family proteins mediate sphingolipid homeostasis.

ORMDL1 ORMDL3 ORMDL2

3.88e-074161320182505
Pubmed

Evidence for Cd101 but not Fcgr1 as candidate for type 1 diabetes locus, Idd10.

FCGR1A FCGR1BP CD101

3.88e-074161315850792
Pubmed

The Ormdl genes regulate the sphingolipid synthesis pathway to ensure proper myelination and neurologic function in mice.

ORMDL1 ORMDL3 ORMDL2

3.88e-074161331880535
Pubmed

Structure and mapping of the gene encoding mouse high affinity Fc gamma RI and chromosomal location of the human Fc gamma RI gene.

CD1D FCGR1A FCGR1BP

9.67e-07516131531670
Pubmed

ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis.

ORMDL1 ORMDL3 ORMDL2

1.93e-066161325691431
Pubmed

In silico screening for palmitoyl substrates reveals a role for DHHC1/3/10 (zDHHC1/3/11)-mediated neurochondrin palmitoylation in its targeting to Rab5-positive endosomes.

ZDHHC11B ZDHHC1 ZDHHC11

3.36e-067161323687301
Pubmed

Localization of the osteocalcin gene cluster on mouse chromosome 3.

CD1D FCGR1A FCGR1BP

5.36e-06816137915557
Pubmed

Identification of host proteins required for HIV infection through a functional genomic screen.

ARHGEF12 NIPSNAP2 PM20D1 PKD1L2 MDN1 NR0B2 COG4 LRIF1 SEC14L1

5.43e-06272161918187620
Pubmed

Dermal TRPV1 innervations engage a macrophage- and fibroblast-containing pathway to activate hair growth in mice.

FCGR1A FCGR1BP SCN10A

8.01e-069161338851191
Pubmed

Coexpression of gap junction proteins in the cumulus-oocyte complex.

CD1D FCGR1A FCGR1BP

8.01e-06916138398132
Pubmed

Identification of a new susceptibility locus for insulin-dependent diabetes mellitus by ancestral haplotype congenic mapping.

HLA-DOA FCGR1A FCGR1BP

1.14e-051016137560085
Pubmed

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling.

PCDH20 FREM2 DCHS1 ITM2C CD276

1.53e-0567161521875946
Pubmed

Molecular cloning, characterization, and genetic mapping of the cDNA coding for a novel secretory protein of mouse. Demonstration of alternative splicing in skin and cartilage.

CD1D FCGR1A FCGR1BP

1.56e-051116137608209
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

WASHC4 UBR4 PIDD1 PKD1L2 ECE1 DST SCN10A ITM2C COG4

2.08e-05322161926514267
Pubmed

Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions.

FCGR1A FCGR1BP

2.13e-052161228814603
Pubmed

ZDHHC11 and ZDHHC11B are critical novel components of the oncogenic MYC-miR-150-MYB network in Burkitt lymphoma.

ZDHHC11B ZDHHC11

2.13e-052161228331227
Pubmed

Involvement of the N-methyl-D-aspartate receptor GluN2D subunit in phencyclidine-induced motor impairment, gene expression, and increased Fos immunoreactivity.

FOS GRIN2D

2.13e-052161224330819
Pubmed

Features and protective efficacy of human mAbs targeting Mycobacterium tuberculosis arabinomannan.

FCGR1A FCGR1BP

2.13e-052161237733444
Pubmed

Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.

FCGR1A FCGR1BP

2.13e-05216129257847
Pubmed

The interaction of N-glycans in Fcγ receptor I α-chain with Escherichia coli K1 outer membrane protein A for entry into macrophages: experimental and computational analysis.

FCGR1A FCGR1BP

2.13e-052161225231998
Pubmed

Lentivirus-mediated knockdown of FcγRI (CD64) attenuated lupus nephritis via inhibition of NF-κB regulating NLRP3 inflammasome activation in MRL/lpr mice.

FCGR1A FCGR1BP

2.13e-052161230190171
Pubmed

ORMDL2 Deficiency Potentiates the ORMDL3-Dependent Changes in Mast Cell Signaling.

ORMDL3 ORMDL2

2.13e-052161233643282
Pubmed

Molecular cloning and expression of the mouse high affinity Fc receptor for IgG.

FCGR1A FCGR1BP

2.13e-05216122136886
Pubmed

FcRγ deficiency improves survival in experimental sepsis by down-regulating TLR4 signaling pathway.

FCGR1A FCGR1BP

2.13e-052161230552619
Pubmed

Sensory Neuron Expressed FcγRI Mediates Postinflammatory Arthritis Pain in Female Mice.

FCGR1A FCGR1BP

2.13e-052161235833115
Pubmed

Differential gene expression modulated by the cytoplasmic domain of Fc gamma RIa (CD64) alpha-chain.

FCGR1A FCGR1BP

2.13e-052161215528358
Pubmed

MTOC reorientation occurs during FcgammaR-mediated phagocytosis in macrophages.

TUBG2 TUBG1

2.13e-052161217442887
Pubmed

Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis.

FCGR1A FCGR1BP

2.13e-052161214991835
Pubmed

Definition of interferon gamma-response elements in a novel human Fc gamma receptor gene (Fc gamma RIb) and characterization of the gene structure.

FCGR1A FCGR1BP

2.13e-05216121402657
Pubmed

ORMDL proteins regulate ceramide levels during sterile inflammation.

ORMDL1 ORMDL3

2.13e-052161227313060
Pubmed

A distinct neurodevelopmental syndrome with intellectual disability, autism spectrum disorder, characteristic facies, and macrocephaly is caused by defects in CHD8.

CHD8 SUPT16H

2.13e-052161230670789
Pubmed

Overexpression of γ-tubulin in non-small cell lung cancer.

TUBG2 TUBG1

2.13e-052161222806905
Pubmed

Mouse FcgammaRI: identification and functional characterization of five new alleles.

FCGR1A FCGR1BP

2.13e-052161210752630
Pubmed

Neuronal FcγRI mediates acute and chronic joint pain.

FCGR1A FCGR1BP

2.13e-052161231211699
Pubmed

Rare loss of function mutations in N-methyl-D-aspartate glutamate receptors and their contributions to schizophrenia susceptibility.

GRIN2C GRIN2D

2.13e-052161229317596
Pubmed

Prevotella intermedia upregulates MMP-1 and MMP-8 expression in human periodontal ligament cells.

MMP1 MMP8

2.13e-052161219708869
Pubmed

Reconstitution of allogeneic hemopoietic stem cells: the essential role of FcR gamma and the TCR beta-chain-FCp33 complex.

FCGR1A FCGR1BP

2.13e-052161216849450
Pubmed

Neurodevelopmental phenotype associated with CHD8-SUPT16H duplication.

CHD8 SUPT16H

2.13e-052161231823155
Pubmed

NMDA GluN2C/2D receptors contribute to synaptic regulation and plasticity in the anterior cingulate cortex of adult mice.

GRIN2C GRIN2D

2.13e-052161233766086
Pubmed

High expression of CPNE5 and CPNE9 predicts positive prognosis in multiple myeloma.

CPNE9 CPNE5

2.13e-052161233780365
Pubmed

CD64 plays a key role in diabetic wound healing.

FCGR1A FCGR1BP

2.13e-052161238524127
Pubmed

Allocation of gamma-tubulin between oocyte cortex and meiotic spindle influences asymmetric cytokinesis in the mouse oocyte.

TUBG2 TUBG1

2.13e-052161217287496
Pubmed

Plasma from patients with sepsis up-regulates the expression of CD49d and CD64 on blood neutrophils.

ITGA4 FCGR1A

2.13e-052161219011162
Pubmed

Developmentally ordered appearance of a functional Fc gamma receptor on TCR V gamma 3 thymocytes. Evidence for stimulation-induced expression.

FCGR1A FCGR1BP

2.13e-05216128077658
Pubmed

Testis-specific hnRNP is expressed in colorectal cancer cells and accelerates cell growth mediating ZDHHC11 mRNA stabilization.

ZDHHC11B ZDHHC11

2.13e-052161235384384
Pubmed

Modulating IgG effector function by Fc glycan engineering.

FCGR1A FCGR1BP

2.13e-052161228289219
Pubmed

Differential expression of murine CGI-105 gene in 3T3-L1 cells by adrenocorticotropic hormones.

FAHD2B FAHD2A

2.13e-052161215774318
Pubmed

Amelioration of Lupus Serum-Induced Skin Inflammation in CD64-Deficient Mice.

FCGR1A FCGR1BP

2.13e-052161235273604
Pubmed

Differential expression of human γ-tubulin isotypes during neuronal development and oxidative stress points to a γ-tubulin-2 prosurvival function.

TUBG2 TUBG1

2.13e-052161228119396
Pubmed

In the Telencephalon, GluN2C NMDA Receptor Subunit mRNA is Predominately Expressed in Glial Cells and GluN2D mRNA in Interneurons.

GRIN2C GRIN2D

2.13e-052161229651654
Pubmed

IgG3-mediated enhancement of the antibody response is normal in Fc gammaRI-deficient mice.

FCGR1A FCGR1BP

2.13e-052161216305642
Pubmed

Fcγ receptor I alpha chain (CD64) expression in macrophages is critical for the onset of meningitis by Escherichia coli K1.

FCGR1A FCGR1BP

2.13e-052161221124939
Pubmed

Macrophages eliminate circulating tumor cells after monoclonal antibody therapy.

FCGR1A FCGR1BP

2.13e-052161224430180
Pubmed

Differential effect of NMDA receptor GluN2C and GluN2D subunit ablation on behavior and channel blocker-induced schizophrenia phenotypes.

GRIN2C GRIN2D

2.13e-052161231110197
Pubmed

Novel 14q11.2 microduplication including the CHD8 and SUPT16H genes associated with developmental delay.

CHD8 SUPT16H

2.13e-052161226834018
Pubmed

Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity.

FCGR1A FCGR1BP

2.13e-052161238885133
Pubmed

Novel Fc gamma receptor I family gene products in human mononuclear cells.

FCGR1A FCGR1BP

2.13e-05216121430234
Pubmed

The FcRgamma chain is not essential for induction of experimental allergic encephalomyelitis (EAE) or anti-myelin antibody-mediated exacerbation of EAE.

FCGR1A FCGR1BP

2.13e-052161215835266
Pubmed

Matrix metalloproteinase-1 (MMP-1) and (MMP-8) gene polymorphisms promote increase and remodeling of the collagen III and V in posterior tibial tendinopathy.

MMP1 MMP8

2.13e-052161229532899
Pubmed

Extracellular mutations of non-obese diabetic mouse FcgammaRI modify surface expression and ligand binding.

FCGR1A FCGR1BP

2.13e-05216128663283
Pubmed

Simultaneous deletion of ORMDL1 and ORMDL3 proteins disrupts immune cell homeostasis.

ORMDL1 ORMDL3

2.13e-052161238715613
Pubmed

Enhanced function of NR2C/2D-containing NMDA receptor in the nucleus accumbens contributes to peripheral nerve injury-induced neuropathic pain and depression in mice.

GRIN2C GRIN2D

2.13e-052161235057644
Pubmed

Sarcalumenin plays a critical role in age-related cardiac dysfunction due to decreases in SERCA2a expression and activity.

SRL ATP2A2

2.13e-052161222119571
Pubmed

Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene.

FCGR1A FCGR1BP

2.13e-05216121830050
Pubmed

Matrix metalloproteinases gene polymorphism haplotype is a risk factor to implant loss: A case-control study.

MMP1 MMP8

2.13e-052161230328228
Pubmed

Functional characteristics of the high affinity IgG receptor, FcγRI.

FCGR1A FCGR1BP

2.13e-052161221325219
Pubmed

NMDA receptors containing GluN2C and GluN2D subunits have opposing roles in modulating neuronal oscillations; potential mechanism for bidirectional feedback.

GRIN2C GRIN2D

2.13e-052161231786200
Pubmed

FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo.

FCGR1A FCGR1BP

2.13e-05216128611682
Pubmed

Direct targeting of genetically modified tumour cells to Fc gammaRI triggers potent tumour cytotoxicity.

FCGR1A FCGR1BP

2.13e-052161216409296
Pubmed

Fcγ Receptor Type I (CD64)-Mediated Impairment of the Capacity of Dendritic Cells to Activate Specific CD8 T Cells by IgG-opsonized Friend Virus.

FCGR1A FCGR1BP

2.13e-052161230744065
Pubmed

Serum anti-Fcgamma receptor autoantibodies in patients with alopecia areata.

FCGR1A FCGR1BP

2.13e-052161217124586
Pubmed

Linkage on chromosome 3 of autoimmune diabetes and defective Fc receptor for IgG in NOD mice.

FCGR1A FCGR1BP

2.13e-05216128480181
Pubmed

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

FCGR1A FCGR1BP

2.13e-052161229576375
Pubmed

Cancer cell-expressed SLAMF7 is not required for CD47-mediated phagocytosis.

CD47 SLAMF7

2.13e-052161230710089
Pubmed

Amelioration of crescentic glomerulonephritis by RhoA kinase inhibitor, Fasudil, through podocyte protection and prevention of leukocyte migration.

FCGR1A FCGR1BP

2.13e-052161218245810
Pubmed

Biochemical characterization of murine Fc gamma RI.

FCGR1A FCGR1BP

2.13e-05216128478020
Pubmed

FcγR-binding affinity of monoclonal murine IgG1s carrying different N-linked Fc oligosaccharides.

FCGR1A FCGR1BP

2.13e-052161231554601
Pubmed

Gene knockout analysis of two gamma-tubulin isoforms in mice.

TUBG2 TUBG1

2.13e-052161215893303
Pubmed

The involvement of FcR mechanisms in antibody-mediated rejection.

FCGR1A FCGR1BP

2.13e-052161218049118
Pubmed

Characterization of an atypical member of the Na+/Cl(-)-dependent transporter family: chromosomal localization and distribution in GABAergic and glutamatergic neurons in the rat brain.

SLC6A1 FCGR1A FCGR1BP

2.69e-051316138294906
Pubmed

Chromosomal mapping of the high affinity Fc gamma receptor gene.

CD1D FCGR1A FCGR1BP

3.41e-051416131347284
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

FNDC3B RHBDD1 WASHC4 AUP1 PROCR CHD8 INTS8 SBSN GTF2H4 MOGS ALG9 CD47 TMEM30A TMEM41B MGA ATP2A2 CD276

4.63e-0512031611729180619
Pubmed

Organization and chromosomal locations of Rap1a/Krev sequences in the mouse.

CD1D FCGR1A FCGR1BP

6.31e-051716131617222
Pubmed

Compartmentalized metabolism supports midgestation mammalian development.

GCM1 ITGA4 LIPT1

6.31e-0517161335388219
Pubmed

Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria.

FCGR1A FCGR1BP

6.37e-053161216841095
Pubmed

Auditory pathway and auditory brainstem response in mice lacking NMDA receptor epsilon 1 and epsilon 4 subunits.

GRIN2C GRIN2D

6.37e-05316129718984
Pubmed

Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G.

FCGR1A FCGR1BP

6.37e-053161222003208
Pubmed

Identification of ITGA4/ITGB7 and ITGAE/ITGB7 expressing subsets of decidual dendritic-like cells within distinct microdomains of the pregnant mouse uterus.

ITGA4 ITGAE

6.37e-053161218562709
Pubmed

Unique monoclonal antibodies define expression of Fc gamma RI on macrophages and mast cell lines and demonstrate heterogeneity among subcutaneous and other dendritic cells.

FCGR1A FCGR1BP

6.37e-053161212594281
Pubmed

Development of proteoglycan-induced arthritis is critically dependent on Fcgamma receptor type III expression.

FCGR1A FCGR1BP

6.37e-053161215880819
Pubmed

ZDHHC19 localizes to the cell membrane of spermatids and is involved in spermatogenesis†.

ZDHHC11B ZDHHC11

6.37e-053161234897408
Pubmed

A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies.

FCGR1A FCGR1BP

6.37e-053161228924242
Pubmed

A universal metabolite repair enzyme removes a strong inhibitor of the TCA cycle.

FAHD2B FAHD2A

6.37e-053161238287013
InteractionMMP27 interactions

TUBG1 MMP1 MMP8 ATP2A2

1.09e-06111564int:MMP27
InteractionFBXO2 interactions

SEMA4B GNPTAB ITGA4 ECE1 TMEM25 ICAM5 CD101 CD47 TMEM231 SLAMF7 PLXNA1 IL6ST EPHA5 CD276

3.97e-0641115614int:FBXO2
InteractionHLA-DQA1 interactions

SEMA4F SEMA4B HLA-DQA2 ATP13A2 MOGS ITM2C LRIF1 PLXNA1

1.04e-051351568int:HLA-DQA1
GeneFamilyADAM metallopeptidase domain containing|CD molecules

PROCR ITGA4 ITGAE CD1D FCGR1A CD101 CD47 SLAMF7 IL6ST CD276

4.19e-053949510471
GeneFamilyFibronectin type III domain containing

FNDC3B EPHA6 DCC ROS1 IL6ST EPHA5

1.99e-04160956555
GeneFamilyZinc fingers DHHC-type|Ankyrin repeat domain containing

ZDHHC11B ZDHHC1 ZDHHC11

2.63e-042495376
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP1 MMP8 MMP26

2.63e-0424953891
GeneFamilyZinc fingers BED-type|Pseudoautosomal region 1

ZBED5 ZBED6

4.04e-04695264
GeneFamilyImmunoglobulin like domain containing

DCC FCGR1A FCGR1BP ICAM5 CD101 CD47

5.41e-04193956594
GeneFamilyGlutamate ionotropic receptor NMDA type subunits

GRIN2C GRIN2D

5.64e-0479521201
GeneFamilyCopines

CPNE9 CPNE5

9.60e-049952829
GeneFamilyDolichyl D-mannosyl phosphate dependent mannosyltransferases|Phosphatidylinositol glycan anchor biosynthesis

PIGV ALG9

9.60e-049952430
GeneFamilyAnoctamins

ANO8 ANO7

1.20e-0310952865
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

TMEM25 SIGLEC11 CD276

1.21e-0340953592
GeneFamilyC1-set domain containing

HLA-DOA HLA-DQA2 CD1D

1.39e-0342953591
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

DCC IGSF10 HMCN1 CD101 SIGLEC11

1.60e-03161955593
GeneFamilyFibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors

EPHA6 EPHA5

2.39e-03149521095
GeneFamilyDyneins, axonemal

DNAH14 DNAH12

3.53e-0317952536
GeneFamilyCD molecules|Integrin alpha subunits

ITGA4 ITGAE

3.96e-03189521160
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA4F SEMA4B

4.88e-0320952736
GeneFamilyTubulins

TUBG2 TUBG1

8.18e-0326952778
GeneFamilyAdenosine receptors|V-set domain containing

CD101 SIGLEC11 SLAMF7 CD276

1.07e-02163954590
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

HLA-DQA2 GPR183 GTF2H4 CD101 PPIP5K1 ITM2C HOMER3

1.44e-0615416078dc8f02534c3ebda30bf9e702e36d0c53d89e5a5
ToppCell367C-Lymphocytic-ILC-ILC-3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SEMA4B TUBG2 ZP3 HMCN1 PPIP5K1 ITM2C SELENOI

1.94e-0616116078de421c61f4d5a6e05fdb20e4d230e2db98ee4d5
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHBDD1 TTC28 CPNE5 DNAH12 ZBED6 ALG9 SEC14L1

2.29e-0616516076e8370b8e747d8ef44a2413a993291a3cd83a77c
ToppCelldroplet-Marrow-BM-1m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD51B SLC16A13 PKD1L2 ZDHHC1 GTF2H4 GVINP1 PPIP5K1

2.58e-0616816072e88d9cb7c80a4656fab290db8b45a5a0599d769
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1A GRIN2D INTS8 ANO8 LIPT1 CAPRIN2 NR0B2

2.90e-061711607b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1A GRIN2D INTS8 ANO8 LIPT1 CAPRIN2 NR0B2

2.90e-0617116079d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

FOS GPR183 GRIN2C ZP3 IGSF10 TMEM130 ITM2C

3.51e-061761607bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-proliferating_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

LRCH2 PROCR TMEM132B BDKRB2 HMCN1 DCHS1 CD276

4.37e-061821607997d37ca2af661c92a56add888762724dfccc890
ToppCellCOVID-19-B_cells-Plasma_cells|COVID-19 / group, cell type (main and fine annotations)

FNDC3B RHBDD1 DCC CPNE5 ITM2C SLAMF7 SEC14L1

4.53e-061831607130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TTC28 MTG2 ECE1 INTS8 LARP4B FARS2 NR0B2

5.23e-061871607689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNDC3B RHBDD1 DCC CPNE5 ITM2C SLAMF7 SEC14L1

5.41e-061881607483d7494704e8732a478b0ffee2f877ee824a6cf
ToppCellILEUM-non-inflamed-(5)_Plasma-(5)_IgG_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

FNDC3B HLA-DQA2 GPR183 DCC CPNE5 ZBED6 ITM2C

5.41e-0618816072156f1bc849ff1cb09ae296d13bedd913ae6b43b
ToppCelldroplet-Pancreas-Endocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOS UBR4 ECE1 LGALS3BP DST ITM2C ATP2A2

6.21e-0619216070dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCell10x5'-Liver-Myeloid_Dendritic|Liver / Manually curated celltypes from each tissue

MAP1A HTR7 HLA-DOA HLA-DQA2 GPR183 CD1D DST

6.65e-061941607e6391bc7073831847c469ef0b0c437118e1f151f
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_interstitial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

HLA-DOA HLA-DQA2 GRIN2D TMCO4 FCGR1A FCGR1BP SIGLEC11

7.11e-061961607e12fc1bfeb42457b204d582d3e19f01e2345cb6a
ToppCellInfluenza-Influenza_Severe-Myeloid-pDC|Influenza_Severe / Disease, condition lineage and cell class

MAP1A HLA-DOA ATP13A2 FMNL3 DST ZBED6 ITM2C

7.35e-061971607e8e6f71e6dc8a695e4321a18543c1df63dd62f3e
ToppCellmild_COVID-19-cDC|World / disease group, cell group and cell class (v2)

HTR7 HLA-DOA HLA-DQA2 GPR183 CD1D DST ITM2C

7.35e-06197160763e7b040c64f1e28b8db79980c7b580caa7d1b95
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells|LPS_only / Treatment groups by lineage, cell group, cell type

CPNE9 MAP1A HLA-DOA GPR183 ATP13A2 CD101 SLAMF7

7.35e-06197160759ddd8ff7dddf3747b988374e1a4d80959db803e
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_only / Treatment groups by lineage, cell group, cell type

SEMA4B CPNE9 MAP1A GPR183 ATP13A2 MOGS MTMR9

7.59e-061981607d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCellSepsis-ICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, condition lineage and cell class

PROCR TMEM25 IGSF10 MOGS ITM2C TMEM231 SLAMF7

7.85e-06199160790ddd686b8f39c6f6134b9b048396cebcf8d0448
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-B-B_memory|COVID-19_Mild / Disease, condition lineage and cell class

ZYG11A SEMA4B HLA-DOA HLA-DQA2 SYBU GPR183 CPNE5

7.85e-06199160754e392b4ebe601d4838739ff7de3ac6b2203c948
ToppCellLPS_only-Myeloid-Dendritic_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR7 GPR183 ITGA4 ATP13A2 SLAMF7 MTMR9

1.60e-051481606cb9365663f9cba35d47b5dd9079f42e88b70d915
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR7 HLA-DOA ITGA4 GVINP1 SLAMF7 CD276

1.66e-05149160648fca6ae33d7722c024b43ce04f4dbce7b6b424b
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEMA4F HTR7 HLA-DOA PIDD1 ITGA4 SLAMF7

2.31e-05158160690ca742739a208d457db087655ba3d1c18a9da57
ToppCelldroplet-Lung-nan-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR7 HLA-DOA PKD1L2 ITGAE MDN1 SLAMF7

2.85e-051641606a67dd181eba275c191f4d0cab13df30eaa3ad913
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HTR7 HLA-DOA GPR183 CD101 SLAMF7 MMP26

3.06e-05166160683d0c26ccee605df6b04bbca31661bf4ff4f22ba
ToppCell5'-Adult-LymphNode-Hematopoietic-Plasma_cells-IgG_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNDC3B RHBDD1 DCC CPNE5 SLAMF7 SEC14L1

3.27e-051681606f5a18123f84c62211d9279e9c41e90122e4c4895
ToppCellASK428-Immune-Mast_cell|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq

SEMA4B MAP1A PROCR CPNE5 ZDHHC1 ITM2C

3.27e-051681606c399fcb4d1d0be48026c2ecabc34a5935e7adf73
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HTR7 HLA-DOA ECE1 ITGAE TMEM25 SLAMF7

3.38e-051691606b2d53159e344fad6fcdc485d5b8f6cf1bf094b1f
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HTR7 HLA-DOA GPR183 ZDHHC1 CD1D DST

3.49e-0517016067bba77ae34a0259fad6ee98cf665ff50f77a1328
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HTR7 HLA-DOA GPR183 ZDHHC1 CD1D DST

3.49e-051701606a43b977a7fe745536cf96b7c080397d9fa73086b
ToppCellmild_COVID-19_(asymptomatic)-cDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

HTR7 HLA-DOA HLA-DQA2 GPR183 DST ITM2C

3.85e-05173160671dc0051c87b84e3cf13cde8858166f2a474b5dc
ToppCellfacs-Aorta-Heart-3m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR7 HLA-DOA ITGA4 ITGAE CD101 SLAMF7

3.85e-051731606513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCellfacs-Lung-Endomucin-24m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIDD1 PKD1L2 TMEM25 MOGS CD101 SLAMF7

3.98e-0517416067565f6d1c743809807d248ab0e098a2474d9c5b9
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAD51B MMS22L HLA-DOA ITGA4 CPSF1 SLAMF7

4.10e-0517516063bca1aac2a2a1f46753b5f9462888f144ed8327b
ToppCellControl-B_cells-Plasma_cells|Control / group, cell type (main and fine annotations)

FNDC3B RHBDD1 DCC CPNE5 SLAMF7 SEC14L1

4.10e-051751606fb23858cfce71509cafbe0d9728e678012ff2962
ToppCellIIF-Lymphocyte-B-B_intermediate|IIF / Disease, Lineage and Cell Type

SEMA4B HLA-DOA HLA-DQA2 GPR183 CPNE5 ITM2C

4.10e-051751606327f8ee3669c3fc5ba50abc3b4f3e068637fd8d8
ToppCell5'-Adult-LymphNode-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNDC3B RHBDD1 DCC CPNE5 SLAMF7 SEC14L1

4.10e-0517516066a093c74a6f3daeff07759d6eec542fc5c709149
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DHX37 TMEM132B TMEM130 MDN1 MOGS MTMR9

4.10e-051751606dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCellCV-Severe-7|CV / Virus stimulation, Condition and Cluster

HLA-DQA2 GNPTAB ITGA4 DST ZBED6 SELENOI

4.24e-0517616063de0c7d77210049e5616db21eed1490a17a5ec2d
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C6orf136 SLC22A14 ITGB1BP2 SRL ATP2A2 NR0B2

4.37e-051771606692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MFSD6L DNAH14 TFCP2L1 YAE1 ATP2A2 PLXNA1

4.37e-051771606e1e45956887371b1c18f1eb479dd930031497520
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C6orf136 SLC22A14 ITGB1BP2 SRL ATP2A2 NR0B2

4.37e-051771606c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCellCV-Severe-7|Severe / Virus stimulation, Condition and Cluster

MMS22L GNPTAB ITGA4 DST ZBED6 SELENOI

4.37e-05177160682fdd6185b368f54f03de389427cbe3071d21a99
ToppCellICU-NoSEP-Myeloid-tDC|ICU-NoSEP / Disease, Lineage and Cell Type

PROCR TMEM25 IGSF10 ITM2C TMEM231 SLAMF7

4.80e-051801606be665e801512f6aaf6b3ecb26153bbdeb24619ac
ToppCellmild_COVID-19_(asymptomatic)-cDC|World / disease group, cell group and cell class (v2)

HTR7 HLA-DOA HLA-DQA2 LGALS3BP DST ITM2C

4.80e-05180160668d1c867734fb2977b01ac686b20bf602f9a6b72
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GCM1 MFSD6L TFCP2L1 DST MMP26 EPHA5

4.95e-05181160640df0afcb6848202da54670e84f22d7c3a515d01
ToppCell3'_v3-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

MAP1A HLA-DQA2 GPR183 ATP13A2 TMEM132B ITM2C

4.95e-0518116063d7f089fb434fbc989f1fa159e22133ae00b2487
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GCM1 MFSD6L TFCP2L1 DST MMP26 EPHA5

4.95e-0518116062b53a65ca5616a7b9f64232c3e0b7212d1e2f063
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic-ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GCM1 MFSD6L TFCP2L1 DST MMP26 EPHA5

4.95e-0518116066aef84616e8d2faf54b7e9e6cd02f33c3066dabc
ToppCell5'-Airway_Nasal-Epithelial-Neuro-endocrine/ionocytic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GCM1 MFSD6L TFCP2L1 DST MMP26 EPHA5

4.95e-05181160640d3829ae4aaf81e8616c3499ff8933137fc1cc4
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIPSNAP2 CPNE5 LIPT1 ITGB1BP2 LRRC27 NR0B2

5.11e-051821606c4a7007c864a9455a7e7447e28ccd380878a6a0f
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNDC3B TUBG2 ITGA4 CPNE5 SLAMF7 SEC14L1

5.11e-051821606626aabfd9ac662c1d189f7c4b660482914d9e669
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIPSNAP2 CPNE5 LIPT1 ITGB1BP2 LRRC27 NR0B2

5.11e-051821606c315d820ffad912c014ba5eac6f5fa6de1a94384
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNDC3B TUBG2 ITGA4 CPNE5 SLAMF7 SEC14L1

5.11e-051821606a00abff41c12b71d5860c494b8c722d649fd5f36
ToppCellfacs-Aorta-Heart-3m-Myeloid-macrophage|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR7 HLA-DOA GPR183 ITGA4 ITGAE SLAMF7

5.11e-051821606df26388c0c46d1c4775103c8e802937b4d4e7470
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma-Plasma_cells|lymph-node_spleen / Manually curated celltypes from each tissue

FNDC3B DCC CPNE5 ITM2C SLAMF7 SEC14L1

5.26e-051831606a6866951866373a1029e04818f4a4a31278c409d
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

EPHA6 HTR7 GRIN2D SLC6A1 SRL KCNS3

5.26e-051831606121791ef84e7ce377ed6f5b7953af8865e04958e
ToppCellfacs-Aorta-Heart-3m-Myeloid-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR7 HLA-DOA GPR183 ITGA4 ITGAE SLAMF7

5.26e-051831606062ec08d66c923f90fee771b1bf8d98bdc7e6c1b
ToppCell367C-Fibroblasts-Fibroblast-D-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

HLA-DOA HLA-DQA2 GPR183 TFCP2L1 FCGR1A FCGR1BP

5.26e-051831606b12b89debc9dd6396188bc8fe44f54c01c560966
ToppCellCOVID-19-B_cells|COVID-19 / group, cell type (main and fine annotations)

RHBDD1 DCC CPNE5 ITM2C SLAMF7 SEC14L1

5.26e-0518316062c016bb59f131a0e821853b085289a3583f0a729
ToppCell10x5'-lymph-node_spleen-Lymphocytic_B_plasma|lymph-node_spleen / Manually curated celltypes from each tissue

FNDC3B DCC CPNE5 ITM2C SLAMF7 SEC14L1

5.26e-051831606beadc69f511cf183e493cb445135f0748ab8b20e
ToppCell367C-Fibroblasts-Fibroblast-D|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

HLA-DOA HLA-DQA2 GPR183 TFCP2L1 FCGR1A FCGR1BP

5.26e-05183160619cc0009f5332b6e4d4274df123eebbfc80b669a
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD1L2 DCC FREM2 HMCN1 ROS1 EPHA5

5.43e-0518416062cbed6462fea2622871bb7e49b0df3d984239281
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_int|lung / Disease (COVID-19 only), tissue and cell type

ZYG11A ITGA4 DCC CPNE5 ITM2C SLAMF7

5.43e-051841606480595a0e2e6aa2a77b7daa36490ae3af3d8dfee
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD1L2 DCC FREM2 HMCN1 ROS1 EPHA5

5.43e-051841606ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD1L2 DCC FREM2 HMCN1 ROS1 EPHA5

5.43e-0518416062b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-DC1|bone_marrow / Manually curated celltypes from each tissue

HLA-DOA HLA-DQA2 DST SLC22A14 HHIPL1 ARHGAP20

5.43e-051841606ee295f6fa898da53883e1358b17f2c2dd177e9a7
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FNDC3B RHBDD1 DCC CPNE5 ITM2C SLAMF7

5.59e-0518516063b77bc49cd3740acc025e162a36282ac09e12198
ToppCellcontrol-Myeloid-pDC|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MAP1A HLA-DOA GPR183 FMNL3 ITM2C SLAMF7

5.76e-051861606fe31e9cf4575ee40b50489593c51d8c36c3cc532
ToppCell10x5'v1-week_12-13-Endothelial-stroma-sinusoidal_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RSPH4A PROCR TMEM132B HMCN1 DCHS1 MMP1

5.76e-051861606e8ead5634686ebaa6a230eea69795d923ce9939d
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|lung / Disease (COVID-19 only), tissue and cell type

ZYG11A RHBDD1 ITGA4 DCC CPNE5 SLAMF7

5.76e-05186160666676d9395172de5707e204826a1c9f73b448cca
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROCR ECE1 DST HMCN1 ARHGAP20 IL6ST

5.76e-05186160641f1674afc17661eccaa779cdeb663db5e45685d
ToppCellcontrol-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MAP1A HLA-DOA GPR183 FMNL3 ITM2C SLAMF7

5.76e-051861606fccee4cfcc887358cf916d974f29627095b5ad9c
ToppCelldroplet-Lung-LUNG-30m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PROCR ECE1 DST HMCN1 ARHGAP20 IL6ST

5.76e-051861606aa006650cf21a2c51dfe1091681f67fdad939107
ToppCell3'_v3-blood-Myeloid_Dendritic-DC2|blood / Manually curated celltypes from each tissue

HLA-DOA HLA-DQA2 GPR183 BDKRB2 DST ITM2C

5.93e-0518716069f3db9f0e5de34aeabfe5984f675bc7a65435df7
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TTC28 MTG2 INTS8 LARP4B FARS2 NR0B2

5.93e-0518716064527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCellCOVID_non-vent-Myeloid-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

HTR7 HLA-DOA HLA-DQA2 FOS GPR183 CD1D

5.93e-051871606936aaca144b79a809617cbe3058bf434a4b3d46a
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Plasma_cells|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FNDC3B RHBDD1 CPNE5 ITM2C SLAMF7 SEC14L1

5.93e-05187160631f36e34669b8fff6905262b4661b59c93e4dc3d
ToppCellLAM-Lymphoid-pDC|Lymphoid / Condition, Lineage and Cell class

MAP1A HLA-DOA GPR183 ATP13A2 ITM2C TMEM19

5.93e-0518716064d9ffd2bbdf1c9869e28991ce9331e4ccf3c0166
ToppCellCOVID_non-vent-Myeloid-Dendritic-cDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

HTR7 HLA-DOA HLA-DQA2 FOS GPR183 CD1D

5.93e-05187160655fe4e8b4f301876716c1af15c34d42164f2358e
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_memory-B_memory-0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SEMA4B HLA-DOA HLA-DQA2 SYBU GPR183 CPNE5

6.11e-051881606229108e7e3db49e1cfd747d69e338394139d95b3
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZYG11A SEMA4B HLA-DOA HLA-DQA2 CPNE5 HOMER3

6.11e-051881606cd833a125a5279ac32a9a9cb9ecd05ae24bea3a9
ToppCell10x5'-blood-Lymphocytic_B-Memory_B_cells|blood / Manually curated celltypes from each tissue

SEMA4B HLA-DOA HLA-DQA2 SYBU CPNE5 ITM2C

6.29e-0518916068aa65ffc396ccc5e86a6d38b99a2d51c34c9b6d2
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HTR7 HLA-DOA HLA-DQA2 GPR183 CD1D DST

6.67e-0519116066cda82a994f4b205cf54590c979d7c9f3be2b4c8
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_6|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HTR7 HLA-DOA HLA-DQA2 GPR183 CD1D DST

6.67e-0519116064257f02856f3510981e9f84d465d91448d6126e2
ToppCellControl-pDC|Control / Disease condition and Cell class

MAP1A GPR183 ATP13A2 FMNL3 ITM2C SLAMF7

6.67e-051911606543e1437a52d04436862dd1c27b4fae95c44fcc8
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DOA HLA-DQA2 GPR183 CD1D DST ITM2C

6.67e-0519116062699e9bb872f2b561bb976dfdc2746e359bc9daf
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 PROCR ECE1 DST HMCN1 IL6ST

6.67e-0519116069fc674a58f20b47255e4457d5195c8cff17b0414
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-DOA HLA-DQA2 GPR183 CD1D DST ITM2C

6.67e-0519116064b94c8b0183ae07d173646b7e7e1d9db04ec9637
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TMEM63B DNAH14 FREM2 LARP4B CD47 ROS1

6.67e-051911606ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellControl-pDC-|Control / Disease condition and Cell class

MAP1A GPR183 ATP13A2 FMNL3 ITM2C SLAMF7

6.67e-0519116061d7b0fae4d114d6db933c18b4eb2066ffa61356d
ToppCell368C-Myeloid-Dendritic|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HLA-DOA HLA-DQA2 FOS GPR183 ITGA4 SLAMF7

6.67e-05191160629f9db28cee6476141b0773682c66e6be940de46
ToppCelldroplet-Lung-LUNG-1m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 PROCR ECE1 DST HMCN1 IL6ST

6.67e-051911606c379a499dabf3c9ed80f47adbb2d949821c5b053
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTC28 FOS ECE1 LGALS3BP DST ATP2A2

6.67e-051911606a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PROCR LGALS3BP DST FCGR1A CD47 CD276

6.87e-051921606e1deb743b1f39b58a46b8df134e79d512a000273
ToppCelldroplet-Lung-1m-Endothelial-venous_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TTC28 PROCR ECE1 HMCN1 ARHGAP20 IL6ST

6.87e-0519216061990dc8a81594018a5bf596be99d0b5f0af0f58f
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SEMA4B HLA-DOA HLA-DQA2 SYBU GPR183 CPNE5

6.87e-051921606debd471f61cf3606b8e9c246add0be5df601af7f
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HTR7 HLA-DOA GPR183 CD1D DST ITM2C

6.87e-051921606dfb9101622f7d2f2c392e850cff07becfc8c655e
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HTR7 HLA-DOA GPR183 CD1D DST ITM2C

6.87e-051921606d39133cf1a20af6f2970188630fc3b27a4cfc9c5
Diseasecomplex cortical dysplasia with other brain malformations 4 (implicated_via_orthology)

TUBG2 TUBG1

2.50e-0521482DOID:0090138 (implicated_via_orthology)
Diseaseasthma (implicated_via_orthology)

BDKRB2 ORMDL1 ORMDL3 ORMDL2

2.82e-05351484DOID:2841 (implicated_via_orthology)
DiseaseCHARGE syndrome (implicated_via_orthology)

CHD8 CHD6

5.16e-0471482DOID:0050834 (implicated_via_orthology)
DiseaseLarge cell carcinoma of lung

TRPM6 ROS1 EPHA5

5.51e-04321483C0345958
Diseasebody weight

MMS22L GTF2A1L EPHA6 TUBG2 ARHGEF12 CHD8 DCC ECE1 CPNE5 DNAH14 TFCP2L1 DNAH12 FARS2 MGA COG4 PLXNA1

6.16e-04126114816EFO_0004338
Diseasecoenzyme Q10 measurement

DCC KCNS3 MMP26

7.82e-04361483EFO_0007836
DiseaseCongenital disorder of glycosylation

MOGS ALG9 COG4

9.17e-04381483cv:C0282577
DiseaseShort Stature, CTCAE

RSPH4A KDM3B

1.10e-03101482C2919142
DiseaseShort stature

RSPH4A KDM3B

1.10e-03101482C0349588
Diseasecongestive heart failure (implicated_via_orthology)

ECE1 MMP1 ATP2A2

1.15e-03411483DOID:6000 (implicated_via_orthology)
Diseaseputamen volume change measurement

DCHS1 TMEM30A

1.88e-03131482EFO_0021495
Diseasethoracic aortic aneurysm (is_marker_for)

MMP1 MMP8

2.19e-03141482DOID:14004 (is_marker_for)
Diseaseautosomal dominant polycystic kidney disease (is_marker_for)

FOS MMP1

2.19e-03141482DOID:898 (is_marker_for)
Diseasechenodeoxycholate measurement

DCC HMCN1

2.51e-03151482EFO_0010471
Diseasepulmonary hypertension (implicated_via_orthology)

ECE1 BDKRB2 MMP1

2.54e-03541483DOID:6432 (implicated_via_orthology)
Diseaseopen-angle glaucoma

FNDC3B ARHGEF12 DST FARS2 LRRC27

2.83e-031911485EFO_0004190
DiseasePROSTATE CANCER, HEREDITARY, 1

TTC28 HLA-DOA LARP4B

3.43e-03601483C4722327
DiseaseFEV/FEC ratio

RAD51B FNDC3B DCC ATP13A2 FREM2 DNAH12 DST HMCN1 KCNS3 HHIPL1 ARHGAP20 MGA SLC14A2 CD276

3.60e-03122814814EFO_0004713
Diseaseessential hypertension (is_implicated_in)

ECE1 ATP2A2

3.63e-03181482DOID:10825 (is_implicated_in)
DiseaseQRS duration

UBR4 FMNL3 ORMDL3 HMCN1 SCN10A SRL

4.02e-032981486EFO_0005055
Diseaseurate measurement, bone density

TRPM6 TTC28 MTG2 GRIN2C PAPPA-AS1 DNAH14 LARP4B FCGR1BP KCNS3

4.14e-036191489EFO_0003923, EFO_0004531
DiseaseHemorrhage

FOS BDKRB2

4.47e-03201482C0019080
Diseasesleep measurement

ECE1 HIPK3 PLEKHM2 SLC14A2

4.84e-031351484EFO_0004870

Protein segments in the cluster

PeptideGeneStartEntry
PVAFILLVWNSQTPA

nan

26

P0DMU3
TIIQLQPLQEPESWA

PROCR

66

Q9UNN8
LNTIQPPFLWVLFVL

BDKRB2

56

P30411
LTPVPQQFSVFNTIW

ARSH

521

Q5FYA8
PFLVIAPLSTITNWE

CHD8

861

Q9HCK8
LPLPQIQALSSAWVV

C6orf136

71

Q5SQH8
IKPQVQPWINSFFSV

COG4

616

Q9H9E3
PSSFLLPDNWQLQFI

ALG9

476

Q9H6U8
SNVNETSVFLEWIPP

EPHA5

366

P54756
LVPNPCTSQIEFSLW

GVINP1

1001

Q7Z2Y8
AVKSALPSLNWFVPL

ERVV-2

446

B6SEH9
SPEPGFSLAQLNLIW

CD276

271

Q5ZPR3
WPAPCLVIAANVFAV

DGAT1

131

O75907
SLSLPFPIQWETVSI

CBLL2

216

Q8N7E2
IALWKLVFTQNNPPV

DCUN1D3

206

Q8IWE4
LVFTQNNPPVLDQWL

DCUN1D3

211

Q8IWE4
SWNALPPQPLAFSEV

ASTE1

391

Q2TB18
AISPFTPEFLVQQRW

ARHGEF12

1466

Q9NZN5
QRLFPWLSPEAAIVS

ANO8

831

Q9HCE9
NAVSIWSNVTPLIFQ

MMP26

126

Q9NRE1
NFISLFWPSLPTGIQ

MMP8

316

P22894
SVTQAELNWAPEILP

RAD51B

351

O15315
NQLLLEFSFWNEPVP

NIPSNAP2

166

O75323
TTVAALPIWNPISEF

PAPPA-AS1

16

Q5QFB9
ISIWPSSIPNLQSVD

INTS8

796

Q75QN2
VNIILSNPWLFEPLI

PM20D1

306

Q6GTS8
PLAPLFALLNNWVEI

ANO7

726

Q6IWH7
KAVITLQPPWVSVFQ

FCGR1BP

21

Q92637
LQPPWVSVFQEETVT

FCGR1BP

26

Q92637
LLSWCPQFQPLASVF

DCHS1

3166

Q96JQ0
VWVPENAPVNTRLAI

PCDH20

216

Q8N6Y1
PFFSIPVVWTLTNVI

ORMDL2

41

Q53FV1
ASAELTVLVPPWFLN

DCC

321

P43146
DNIFPPVVNITWLSN

HLA-DQA2

136

P01906
QIQTWLPQARFDPAV

MDN1

3231

Q9NU22
SITALVVWLPANPTE

MAP1A

246

P78559
WIFQDNLQPFTPSLV

LRIF1

291

Q5T3J3
TQAEAWPSVPTDLLQ

LGALS3BP

291

Q08380
IFIVTNGQIPSWLNL

GNPTAB

346

Q3T906
QLPLAPATSFPFWNL

MGA

751

Q8IWI9
QIPLPAFNWVKASQT

ITGB1BP2

236

Q9UKP3
AISTSPDLQWLVQPA

FOS

66

P01100
PDLQWLVQPALVSSV

FOS

71

P01100
PFLNISRVVLTSPWE

HHIPL1

231

Q96JK4
TNPLFEANNLVIWPS

MTMR9

471

Q96QG7
EANNLVIWPSVAPQS

MTMR9

476

Q96QG7
PALVEQTAAVLQAWP

HIPK1

736

Q86Z02
FQPQPVISIIQLFGW

MMS22L

761

Q6ZRQ5
PWLTETQSIISQLPA

DST

5951

Q03001
PILFFWQNSPSVVIG

LIPT1

61

Q9Y234
WVTILPVDSQAPEIF

FREM2

1056

Q5SZK8
QQFPLYSLITPQTWS

LARP4B

351

Q92615
VFQIDPATKRNWIPA

HOMER3

16

Q9NSC5
IQLISPVSWEAIPNA

CPSF1

1076

Q10570
LAAFNVDVARPWLTP

ITGAE

16

P38570
LVSIAFPIPICQQWE

MFSD6L

336

Q8IWD5
PLVLQAWNVPDLSAG

PLXNA1

581

Q9UIW2
LSAVSQEPFWADLQP

ICAM5

26

Q9UMF0
TQPPEEFVWAVALLL

PEAK3

271

Q6ZS72
LFAWLIPPSLNQRVE

DNAH12

1711

Q6ZR08
RVSIAQWPALTFTPL

KDM3B

111

Q7LBC6
WKNPLNIIDFVSIIP

KCNS3

251

Q9BQ31
TVLLQAQKWPFQPSR

FAHD2A

11

Q96GK7
TVAFLRNLPSFWQLP

NR0B2

66

Q15466
PFFSVPVAWTLTNII

ORMDL1

41

Q9P0S3
AWQQVTPLAPATTTL

HIPK3

686

Q9H422
QPTVLNLTSPEALWV

PKD1L2

1171

Q7Z442
IPLPKLTWTFNNNII

HMCN1

4286

Q96RW7
IELNTTIVLPPRNFW

ITM2C

166

Q9NQX7
NVFWTSNPGLPLLTE

MOGS

261

Q13724
DLPIWPEQQAVFFTL

OR1J4

16

Q8NGS1
GFPEALIPVQLLWVN

ATP2A2

781

P16615
FLTLAQPWFVPLNRT

ATP13A2

1021

Q9NQ11
IQPVWQILALYSDSP

IGSF10

371

Q6WRI0
LKVPLTVTWQFQPAS

CD101

571

Q93033
TVQLVWKTLPPFEAN

IL6ST

346

P40189
GLIWSQFVQTLPIQT

DACT1

781

Q9NYF0
DNIFPPVINITWLRN

HLA-DOA

136

P06340
QVPASITQILRNPWF

LINC01599

111

Q8WXQ3
IQAFASGWPPVLLDQ

GFRA4

246

Q9GZZ7
AQLPVLPWSEVTFLA

FAHD2B

86

Q6P2I3
PFLIIAPLSTITNWE

CHD6

511

Q8TD26
PTQEAPLWVNLAIQV

CD1D

151

P15813
NIQARAVVLSWAPPV

FNDC3B

286

Q53EP0
LPVFNWTALKPNQIS

FMNL3

571

Q8IVF7
VVKNTLNPVWQPFSI

CPNE9

191

Q8IYJ1
NNPIITQFFPTLLLW

TMEM63B

471

Q5T3F8
SLPLTWSFQEGVQLP

GCM1

201

Q9NP62
HPLPVITAATFLAWQ

BRF2

221

Q9HAW0
WQPILTAGTVLPIFF

TMEM30A

41

Q9NV96
VIAWLCPSSPNFILN

CAPRIN2

31

Q6IMN6
IPWSDLVPNDQTLIQ

DNAH14

1846

Q0VDD8
APTANWLANASVINP

ITGA4

71

P13612
KAVITLQPPWVSVFQ

FCGR1A

21

P12314
LQPPWVSVFQEETVT

FCGR1A

26

P12314
VKVFPTWLAPNLITF

SELENOI

41

Q9C0D9
RILSSPWIQVCNNFP

CYP2C18

206

P33260
TLAPAINWLPFLNTI

ECE1

341

P42892
WFSPNENILIVIFPI

CD47

136

Q08722
LEFSPKNTVLATWQP

EIF2A

81

Q9BY44
VSSVEVQWIPALLPS

DHX37

996

Q8IY37
PVPWNLDSIIQFGLN

SLC22A14

136

Q9Y267
FPVLWTLVSPFIDDN

SEC14L1

441

Q92503
PPLVQLIFWSLNAGL

SDIM1

66

Q6ZPB5
VNTPFINLPALWRSV

SBSN

571

Q6UWP8
NPVWQTFSIPVRALC

CPNE5

226

Q9HCH3
IPSDVWLFAPLETLN

LRCH2

126

Q5VUJ6
PFVSVPVVWTLTNLI

ORMDL3

41

Q8N138
QQDVGLWLLFTPPQA

PIDD1

391

Q9HB75
EFSQDSQQLLPPWVI

PLEKHM2

936

Q8IWE5
NINETALILEWSPPS

EPHA6

341

Q9UF33
AFNLAVCVAPSILWP

ARHGAP20

506

Q9P2F6
IPQYAIAVLQSNLWP

RSPH4A

616

Q5TD94
NIPPVTLATLALNIW

RHBDD1

26

Q8TEB9
AVTQLPISPLWAILF

SLC6A1

371

P30531
WLNAPAFVAAVALSP

SEMA4F

221

O95754
PASLLSVANVIDNPW

TMCO4

356

Q5TGY1
SQFEVTVWAPRLPLQ

TMEM132B

506

Q14DG7
VIPQDFFQLLPNLTW

LRRC27

81

Q9C0I9
EVELNFISVFWPQLP

MMP1

311

P03956
FISVFWPQLPNGLEA

MMP1

316

P03956
WILVFAQTLPLLINP

GPR183

156

P32249
QFFITVVPTPWLDNK

PPWD1

591

Q96BP3
PSPLWLSFTVEELQI

NICN1

121

Q9BSH3
VLQDVFTLSPSPQDW

SEMA4B

321

Q9NPR2
LLFVVDLSQPEPWTQ

MTG2

306

Q9H4K7
QEAEQLFLSSPAWLP

SKIV2L

56

Q15477
LFFVTKVQWPPAEQL

IQANK1

531

A8MXQ7
SPTQLNAVEFLWDPA

TFCP2L1

146

Q9NZI6
SSALVNATEWPPFVV

SUPT16H

821

Q9Y5B9
ASITLPPLFGWAQNV

HTR7

211

P34969
SWPFSIQDVVQPLTL

AUP1

176

Q9Y679
FLEQPLPQAAVALWV

GTF2H4

61

Q92759
PNFLLAAPVAILVAW

PIGV

326

Q9NUD9
WLPLEANPEVTNQFL

UCHL3

6

P15374
PQPSVQEWLVSIYIF

TRPM6

866

Q9BX84
WDPLPAAFLLSVVAI

SLC16A13

246

Q7RTY0
ANFIPWGPASIQVAL

TUBG1

346

P23258
APVVPTVLWAFSTQR

SYBU

616

Q9NX95
SVIQTSVPQLNPWSL

GTF2A1L

166

Q9UNN4
DFIANPTVWVSVPIA

SCN10A

986

Q9Y5Y9
ALFWSLAPLINVTEP

SRL

271

Q86TD4
ASQAVTLWDLAPTPQ

TLE7

226

A0A1W2PR48
VPENTSLQFNWKAPL

ROS1

1666

P08922
IVWTFNTTPLVTIQP

SLAMF7

51

Q9NQ25
TWLLFLPLFPVQVQT

ZDHHC11

216

Q9H8X9
NPSPTWILEQTASLV

YAE1

196

Q9NRH1
NDLDISAPQWPIIAF

TMEM19

246

Q96HH6
LASAPIQVSISVQLW

TTC28

1876

Q96AY4
NAWVRNPFTVTVKPA

ZBED5

571

Q49AG3
QIGLWLSPNFLIPSF

ZBED6

546

P86452
NVTTVLNDPNPIWLV

TMEM231

221

Q9H6L2
KVPAITLTANIIWFP

WASHC4

346

Q2M389
QVWPSRIQPAVFAFP

TMEM130

331

Q8N3G9
ANFIPWGPASIQVAL

TUBG2

346

Q9NRH3
ITPFLPNWFINITSP

TMEM41B

206

Q5BJD5
PNWFINITSPVINVP

TMEM41B

211

Q5BJD5
TWLLFLPLFPVQVQT

ZDHHC11B

216

P0C7U3
PAVINDISFWLPSEN

FARS2

361

O95363
YWLQPSLQPSSVISI

UBR4

2251

Q5T4S7
WDLPVFTLPFNIAVT

SLC14A2

231

Q15849
PLLGNFSQPEVQLWA

ZYG11A

676

Q6WRX3
GNVSSQAILPTWLPF

ZP3

146

P21754
SQPPATLSWVLQDRV

SIGLEC11

291

Q96RL6
LFALVRANPPANVTW

TMEM25

151

Q86YD3
LAPQFQIPWSIPTEA

PPIP5K1

361

Q6PFW1
VWFVFLPAAPVETQA

ZDHHC1

226

Q8WTX9
VHTWPFPLLSFQQLL

LRRC14

51

Q15048
LWALVFNNSVPIENP

GRIN2C

606

Q14957
LWALVFNNSVPVENP

GRIN2D

636

O15399