Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein serine/threonine phosphatase inhibitor activity	PPP1R17 PPP1R8 PPP1R1B	4.70e-05	15	96	3	GO:0004865
GeneOntologyMolecularFunction	protein phosphatase regulator activity	PPP1R17 PPP1R7 PPP1R8 PPP4R3C PPP1R1B	1.21e-04	100	96	5	GO:0019888
GeneOntologyMolecularFunction	E-box binding	NEUROD4 NEUROD1 NEUROD6 HDAC1	2.12e-04	61	96	4	GO:0070888
GeneOntologyMolecularFunction	phosphatase regulator activity	PPP1R17 PPP1R7 PPP1R8 PPP4R3C PPP1R1B	2.15e-04	113	96	5	GO:0019208
GeneOntologyCellularComponent	nuclear protein-containing complex	CDK8 ERCC5 SYNE1 RSF1 BUD13 CCDC12 ARID1A EZH2 DHX8 PPP1R8 ZC3H11A MTA1 NEUROD1 POLR3E ASCC2 TAF11 HDAC1 CBX2	4.86e-05	1377	96	18	GO:0140513
GeneOntologyCellularComponent	ATPase complex	RSF1 ARID1A MTA1 VCP HDAC1	3.23e-04	129	96	5	GO:1904949
GeneOntologyCellularComponent	chromatin	TBX22 NEUROD4 RSF1 NAP1L3 CHD2 IRX3 ARID1A EZH2 IRX4 PRDM10 MTA1 NEUROD1 HOXC8 TSHZ1 NEUROD6 HDAC1 CBX2	3.80e-04	1480	96	17	GO:0000785
Domain	Neurogenic_DUF	NEUROD4 NEUROD1 NEUROD6	4.76e-07	4	93	3	IPR022575
Domain	Neuro_bHLH	NEUROD4 NEUROD1 NEUROD6	4.76e-07	4	93	3	PF12533
Domain	TF_bHLH_NeuroD	NEUROD4 NEUROD1 NEUROD6	4.76e-07	4	93	3	IPR016637
Domain	IRO	IRX3 IRX4	3.63e-04	6	93	2	SM00548
Domain	Iroquois_homeo	IRX3 IRX4	3.63e-04	6	93	2	IPR003893
Domain	FERM_M	FRMD6 MYO15A EPB41	1.55e-03	46	93	3	PF00373
Domain	FERM_central	FRMD6 MYO15A EPB41	1.87e-03	49	93	3	IPR019748
Domain	FERM_domain	FRMD6 MYO15A EPB41	1.87e-03	49	93	3	IPR000299
Domain	FERM_1	FRMD6 MYO15A EPB41	1.98e-03	50	93	3	PS00660
Domain	FERM_2	FRMD6 MYO15A EPB41	1.98e-03	50	93	3	PS00661
Domain	FERM_3	FRMD6 MYO15A EPB41	1.98e-03	50	93	3	PS50057
Domain	Band_41_domain	FRMD6 MYO15A EPB41	1.98e-03	50	93	3	IPR019749
Domain	B41	FRMD6 MYO15A EPB41	1.98e-03	50	93	3	SM00295
Domain	-	ARID1A ARID3B	2.47e-03	15	93	2	1.10.150.60
Domain	BRIGHT	ARID1A ARID3B	2.47e-03	15	93	2	SM00501
Domain	ARID_dom	ARID1A ARID3B	2.47e-03	15	93	2	IPR001606
Domain	ARID	ARID1A ARID3B	2.47e-03	15	93	2	PS51011
Domain	ARID	ARID1A ARID3B	2.47e-03	15	93	2	PF01388
Domain	Homeobox_KN	IRX3 IRX4	3.18e-03	17	93	2	PF05920
Domain	Homeobox_KN_domain	IRX3 IRX4	3.18e-03	17	93	2	IPR008422
Domain	Chromodomain_CS	CHD2 CBX2	3.56e-03	18	93	2	IPR023779
Domain	PDEase	PDE4B PDE6B	3.97e-03	19	93	2	IPR023088
Domain	PDEase_I	PDE4B PDE6B	4.84e-03	21	93	2	PF00233
Domain	PDEASE_I	PDE4B PDE6B	4.84e-03	21	93	2	PS00126
Domain	PDEase_CS	PDE4B PDE6B	4.84e-03	21	93	2	IPR023174
Domain	-	PDE4B PDE6B	5.31e-03	22	93	2	1.10.1300.10
Domain	PDEase_catalytic_dom	PDE4B PDE6B	5.80e-03	23	93	2	IPR002073
Domain	HDc	PDE4B PDE6B	6.30e-03	24	93	2	SM00471
Domain	HD/PDEase_dom	PDE4B PDE6B	6.30e-03	24	93	2	IPR003607
Domain	Chromo_domain	CHD2 CBX2	6.30e-03	24	93	2	IPR023780
Domain	FERM_C	FRMD6 EPB41	7.38e-03	26	93	2	PF09380
Domain	Chromo	CHD2 CBX2	7.38e-03	26	93	2	PF00385
Domain	FERM_C	FRMD6 EPB41	7.94e-03	27	93	2	SM01196
Domain	FERM_PH-like_C	FRMD6 EPB41	7.94e-03	27	93	2	IPR018980
Domain	CHROMO_1	CHD2 CBX2	8.52e-03	28	93	2	PS00598
Domain	CHROMO_2	CHD2 CBX2	8.52e-03	28	93	2	PS50013
Pathway	WP_ENDOPLASMIC_RETICULUM_STRESS_RESPONSE_IN_CORONAVIRUS_INFECTION	PPP1R7 PPP1R8 PPP1R1B PPP1R3F	6.54e-05	46	67	4	M39901
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	PUF60 CANX RSF1 NOC3L CHD2 NOL10 ARID1A DHX8 ZC3H11A RRP9 NOP2 VCP	2.89e-07	653	97	12	22586326
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	CALD1 PUF60 CCDC174 RSF1 NOC3L BUD13 NOL10 ARID1A ARID3B ZC3H11A MTA1 NOP2 EPB41 CBX2	4.21e-07	954	97	14	36373674
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	DCAF15 CALD1 SYNE1 CANX BUD13 CCDC12 ARID1A PTMS PPP1R7 PPP1R8 HNRNPUL2 RRP9 NOP2 VCP NAA16	7.30e-07	1155	97	15	20360068
Pubmed	Alterations in the interactome of serine/threonine protein phosphatase type-1 in atrial fibrillation patients.	PPP1R7 PPP1R8 VCP	1.17e-06	8	97	3	25593058
Pubmed	Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.	ST13P4 CALD1 PUF60 CANX ARID1A ARID3B PTMS MTA1 NOP2 VCP	1.58e-06	506	97	10	30890647
Pubmed	Hoxa2 Selects Barrelette Neuron Identity and Connectivity in the Mouse Somatosensory Brainstem.	MAPT EZH2 BTBD3	1.75e-06	9	97	3	26489473
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	CALD1 PUF60 SYNE1 CANX NOC3L NOL10 DHX8 HNRNPUL2 TCF25 NOP2 EPB41 VCP HDAC1	2.41e-06	949	97	13	36574265
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	PUF60 SYNE1 CANX NOC3L CHD2 NOL10 DHX8 ZC3H11A HNRNPUL2 RRP9 NOP2 VCP	2.64e-06	807	97	12	22681889
Pubmed	Probing the interaction between the histone methyltransferase/deacetylase subunit RBBP4/7 and the transcription factor BCL11A in epigenetic complexes.	EZH2 MTA1 HDAC1	3.41e-06	11	97	3	29263092
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SYNE1 NOC3L BUD13 CHD2 NOL10 EZH2 DHX8 SLC9A1 ZC3H11A MTA1 GZF1 RRP9 ASCC2 PALM3 EPB41 HDAC1	3.77e-06	1497	97	16	31527615
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	CHD2 ARID1A EZH2 MTA1 HDAC1 CBX2	5.41e-06	157	97	6	30186101
Pubmed	Basic helix-loop-helix transcription factors cooperate to specify a cortical projection neuron identity.	NEUROD4 NEUROD1 NEUROD6	7.49e-06	14	97	3	18160702
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	PUF60 CANX NOC3L NOL10 ARID1A MTA1 HNRNPUL2 ASCC2 NOP2 HDAC1	7.63e-06	605	97	10	28977666
Pubmed	Autosomal dominant VCP hypomorph mutation impairs disaggregation of PHF-tau.	MAPT VCP	7.70e-06	2	97	2	33004675
Pubmed	Molecular analysis of a candidate metastasis-associated gene, MTA1: possible interaction with histone deacetylase 1.	MTA1 HDAC1	7.70e-06	2	97	2	10840944
Pubmed	Tau filaments with the chronic traumatic encephalopathy fold in a case of vacuolar tauopathy with VCP mutation D395G.	MAPT VCP	7.70e-06	2	97	2	38758288
Pubmed	Patients with a phenotype consistent with facioscapulohumeral muscular dystrophy display genetic and epigenetic heterogeneity.	CAPN3 VCP	7.70e-06	2	97	2	21984748
Pubmed	NOP2 facilitates EZH2-mediated epithelial-mesenchymal transition by enhancing EZH2 mRNA stability via m5C methylation in lung cancer progression.	EZH2 NOP2	7.70e-06	2	97	2	39013911
Pubmed	EZH2 Palmitoylation Mediated by ZDHHC5 in p53-Mutant Glioma Drives Malignant Development and Progression.	ZDHHC5 EZH2	7.70e-06	2	97	2	28775165
Pubmed	Malignant potential of Barrett's esophagus: special reference to HDAC-1 and MTA-1 expression.	MTA1 HDAC1	7.70e-06	2	97	2	21661415
Pubmed	Prognostic significance of EZH2 and ARID1A expression in urothelial carcinoma: an immunohistochemical study.	ARID1A EZH2	7.70e-06	2	97	2	34493171
Pubmed	Expression of histone deacetylase 1 and metastasis-associated protein 1 as prognostic factors in colon cancer.	MTA1 HDAC1	7.70e-06	2	97	2	21617866
Pubmed	Platelet-derived growth factor C and calpain-3 are modulators of human melanoma cell invasiveness.	CAPN3 PDGFC	7.70e-06	2	97	2	24126726
Pubmed	Neuronal basic helix-loop-helix proteins (NEX and BETA2/Neuro D) regulate terminal granule cell differentiation in the hippocampus.	NEUROD1 NEUROD6	7.70e-06	2	97	2	10804213
Pubmed	Class I HDACs share a common mechanism of regulation by inositol phosphates.	MTA1 HDAC1	7.70e-06	2	97	2	23791785
Pubmed	Nuclear Inhibitor of Protein Phosphatase 1 (NIPP1) Regulates CNS Tau Phosphorylation and Myelination During Development.	MAPT PPP1R8	7.70e-06	2	97	2	36198882
Pubmed	Hypoxia-induced NIPP1 activation enhances metastatic potential and predicts poor prognosis in hepatocellular carcinoma.	EZH2 PPP1R8	7.70e-06	2	97	2	27644248
Pubmed	The cytokine IL-27 reduces inflammation and protects photoreceptors in a mouse model of retinal degeneration.	PDE6B IL27	7.70e-06	2	97	2	36064575
Pubmed	SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.	NOC3L BUD13 NOL10 CCDC12 HNRNPUL2 RRP9 NOP2	8.50e-06	259	97	7	30404004
Pubmed	A census of human transcription factors: function, expression and evolution.	TBX22 NEUROD4 NOC3L IRX3 EZH2 IRX4 HIVEP3 ZC3H11A NEUROD1 HOXC8 TSHZ1 NEUROD6	8.70e-06	908	97	12	19274049
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	NOC3L BUD13 NOL10 DHX8 ARID3B ZC3H11A HNRNPUL2 RRP9 TCF25 NOP2 HDAC1	9.02e-06	759	97	11	35915203
Pubmed	Evaluation of TRAP-sequencing technology with a versatile conditional mouse model.	PTMS NEUROD1 PPP1R1B NEUROD6	1.09e-05	49	97	4	24165879
Pubmed	Proteomic characterization of protein phosphatase 1 complexes in ischemia-reperfusion and ischemic tolerance.	PDE6B PPP1R1B VCP	1.15e-05	16	97	3	17683050
Pubmed	Development of a diagnostic genetic test for simplex and autosomal recessive retinitis pigmentosa.	ABCA4 PDE6B RPGR	1.66e-05	18	97	3	20591486
Pubmed	Neurogenin 2 has an essential role in development of the dentate gyrus.	NEUROD4 NEUROD1 NEUROD6	1.97e-05	19	97	3	18448566
Pubmed	Decreases in valosin-containing protein result in increased levels of tau phosphorylated at Ser262/356.	MAPT VCP	2.31e-05	3	97	2	21983102
Pubmed	Mediator complex cooperatively regulates transcription of retinoic acid target genes with Polycomb Repressive Complex 2 during neuronal differentiation.	CDK8 EZH2	2.31e-05	3	97	2	26002960
Pubmed	The deletion of the protein phosphatase 1 regulator NIPP1 in testis causes hyperphosphorylation and degradation of the histone methyltransferase EZH2.	EZH2 PPP1R8	2.31e-05	3	97	2	30305391
Pubmed	Clinical and genetic investigations of three Moroccan families with retinitis pigmentosa phenotypes.	ABCA4 PDE6B	2.31e-05	3	97	2	33633436
Pubmed	Crosstalk between ATF4 and MTA1/HDAC1 promotes osteosarcoma progression.	MTA1 HDAC1	2.31e-05	3	97	2	26797758
Pubmed	A TGF-β-MTA1-SOX4-EZH2 signaling axis drives epithelial-mesenchymal transition in tumor metastasis.	EZH2 MTA1	2.31e-05	3	97	2	31811272
Pubmed	Structural basis of ubiquitin-independent PP1 complex disassembly by p97.	PPP1R7 VCP	2.31e-05	3	97	2	37264685
Pubmed	New genes, new dilemmas: FTLD genetics and its implications for families.	MAPT VCP	2.31e-05	3	97	2	18166610
Pubmed	Optimization of in vivo confocal autofluorescence imaging of the ocular fundus in mice and its application to models of human retinal degeneration.	ABCA4 PDE6B	2.31e-05	3	97	2	22169101
Pubmed	The chromatin remodeler RSF1 controls centromeric histone modifications to coordinate chromosome segregation.	RSF1 HDAC1	2.31e-05	3	97	2	30242288
Pubmed	Expression of hypoxia-inducible factor-1alpha, histone deacetylase 1, and metastasis-associated protein 1 in pancreatic carcinoma: correlation with poor prognosis with possible regulation.	MTA1 HDAC1	2.31e-05	3	97	2	18362831
Pubmed	Consequences of the depletion of zygotic and embryonic enhancer of zeste 2 during preimplantation mouse development.	EZH2 HDAC1	2.31e-05	3	97	2	12900441
Pubmed	Long non-coding RNA profiling links subgroup classification of endometrioid endometrial carcinomas with trithorax and polycomb complex aberrations.	EZH2 CBX2	2.31e-05	3	97	2	26431491
Pubmed	Cbx2 targets PRC1 to constitutive heterochromatin in mouse zygotes in a parent-of-origin-dependent manner.	EZH2 CBX2	2.31e-05	3	97	2	25801166
Pubmed	ARID1A influences HDAC1/BRD4 activity, intrinsic proliferative capacity and breast cancer treatment response.	ARID1A HDAC1	2.31e-05	3	97	2	31913353
Pubmed	Developmental Switch in Spike Timing-Dependent Plasticity and Cannabinoid-Dependent Reorganization of the Thalamocortical Projection in the Barrel Cortex.	MAPT NEUROD6	2.31e-05	3	97	2	27358460
Pubmed	The transcriptional repression by NIPP1 is mediated by Polycomb group proteins.	EZH2 PPP1R8	2.31e-05	3	97	2	17804093
Pubmed	FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections.	NEUROD1 ROBO2 NEUROD6	2.32e-05	20	97	3	30392794
Pubmed	The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.	ABCA4 PDE6B MAPT CANX RTN4 PPP1R7 VPS33B EPB41 VCP	2.48e-05	552	97	9	36293380
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	ST13P4 PUF60 RSF1 CHD2 CCDC12 PPP1R8 ZC3H11A MTA1 HNRNPUL2 MYO15A VCP HDAC1	2.59e-05	1014	97	12	32416067
Pubmed	The Gsh2 homeodomain gene controls multiple aspects of telencephalic development.	NEUROD1 PPP1R1B NEUROD6	2.70e-05	21	97	3	11060228
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	RTN4 DHX8 ARID3B PRDM10 MTA1 VPS33B TCF25 ASCC2 HDAC1	2.78e-05	560	97	9	35241646
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	DCAF15 PUF60 SYNE1 CANX DHX8 ZC3H11A HNRNPUL2 NOP2 VCP HDAC1	3.15e-05	714	97	10	28302793
Pubmed	Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development.	ARID1A EZH2 NEUROD1 NEUROD6	3.38e-05	65	97	4	26655900
Pubmed	ZBTB2 protein is a new partner of the Nucleosome Remodeling and Deacetylase (NuRD) complex.	RSF1 NOC3L NOL10 EZH2 MTA1 NOP2 HDAC1	4.02e-05	330	97	7	33301849
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	ARID1A MTA1 HDAC1 CBX2	4.28e-05	69	97	4	28481362
Pubmed	Cdc42 regulates cofilin during the establishment of neuronal polarity.	MAPT NEUROD6	4.60e-05	4	97	2	18045906
Pubmed	FEZF2, a novel 3p14 tumor suppressor gene, represses oncogene EZH2 and MDM2 expression and is frequently methylated in nasopharyngeal carcinoma.	EZH2 HDAC1	4.60e-05	4	97	2	23677067
Pubmed	The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers.	ARID1A EZH2	4.60e-05	4	97	2	28262751
Pubmed	Requirement of multiple basic helix-loop-helix genes for retinal neuronal subtype specification.	NEUROD4 NEUROD1	4.60e-05	4	97	2	15105417
Pubmed	Antagonistic interaction between Ezh2 and Arid1a coordinates root patterning and development via Cdkn2a in mouse molars.	ARID1A EZH2	4.60e-05	4	97	2	31259687
Pubmed	Synaptogenic activity of the axon guidance molecule Robo2 underlies hippocampal circuit function.	ROBO2 NEUROD6	4.60e-05	4	97	2	34686348
Pubmed	Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A.	EZH2 HDAC1	4.60e-05	4	97	2	15077161
Pubmed	The stem cell-associated transcription co-factor, ZNF521, interacts with GLI1 and GLI2 and enhances the activity of the Sonic hedgehog pathway.	ZNF521 HDAC1	4.60e-05	4	97	2	31558698
Pubmed	Genetic mapping of four mouse bHLH genes related to Drosophila proneural gene atonal.	NEUROD4 NEUROD6	4.60e-05	4	97	2	8938455
Pubmed	Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation.	MAPT VCP	4.60e-05	4	97	2	23719816
Pubmed	NeuroD factors regulate cell fate and neurite stratification in the developing retina.	NEUROD1 NEUROD6	4.60e-05	4	97	2	21593321
Pubmed	p57Kip2 is a repressor of Mash1 activity and neuronal differentiation in neural stem cells.	NEUROD1 NEUROD6	4.60e-05	4	97	2	19590511
Pubmed	The topology of chromatin-binding domains in the NuRD deacetylase complex.	MTA1 HDAC1	4.60e-05	4	97	2	33264408
Pubmed	Loss of miR-26b-5p promotes gastric cancer progression via miR-26b-5p-PDE4B/CDK8-STAT3 feedback loop.	CDK8 PDE4B	4.60e-05	4	97	2	36737782
Pubmed	The polycomb component Ring1B regulates the timed termination of subcerebral projection neuron production during mouse neocortical development.	EZH2 NEUROD6	4.60e-05	4	97	2	25344075
Pubmed	Transcriptional repression of oestrogen receptor by metastasis-associated protein 1 corepressor.	MTA1 HDAC1	4.60e-05	4	97	2	11146623
Pubmed	A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.	MTA1 HDAC1	4.60e-05	4	97	2	30228260
Pubmed	A pair of E3 ubiquitin ligases compete to regulate filopodial dynamics and axon guidance.	MAPT NEUROD6	4.60e-05	4	97	2	31820781
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	RSF1 CHD2 CCDC12 ARID1A EZH2 ARID3B ZC3H11A MTA1	5.22e-05	469	97	8	27634302
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	RSF1 CHD2 EZH2 DHX8 ARID3B MTA1 NOP2 HDAC1 CBX2	5.24e-05	608	97	9	36089195
Pubmed	HIV-1 Vpr induces cell cycle arrest and enhances viral gene expression by depleting CCDC137.	NOC3L EZH2 ARID3B ZC3H11A NOP2	6.13e-05	148	97	5	32538781
Pubmed	ZMYM3 regulates BRCA1 localization at damaged chromatin to promote DNA repair.	RSF1 ARID1A EZH2 MTA1 HDAC1	6.54e-05	150	97	5	28242625
Pubmed	Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice.	NEUROD1 ROBO2 NEUROD6	6.55e-05	28	97	3	35666215
Pubmed	Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons.	ZNF521 FRMD6 PPP1R1B	7.29e-05	29	97	3	31491374
Pubmed	Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis.	PDE6B NEUROD1 NEUROD6	7.29e-05	29	97	3	30048641
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	NOC3L DHX8 ZC3H11A HNRNPUL2 RRP9 TCF25 NOP2	7.44e-05	364	97	7	24778252
Pubmed	Heat shock factor 1 represses estrogen-dependent transcription through association with MTA1.	MTA1 HDAC1	7.66e-05	5	97	2	17922035
Pubmed	Recruitment of distinct chromatin-modifying complexes by tamoxifen-complexed estrogen receptor at natural target gene promoters in vivo.	MTA1 HDAC1	7.66e-05	5	97	2	14722073
Pubmed	Targeted substrate loop insertion by VCP/p97 during PP1 complex disassembly.	PPP1R7 VCP	7.66e-05	5	97	2	34824462
Pubmed	The phosphatase interactor NIPP1 regulates the occupancy of the histone methyltransferase EZH2 at Polycomb targets.	EZH2 PPP1R8	7.66e-05	5	97	2	20671031
Pubmed	Transcriptional repression mediated by the human polycomb-group protein EED involves histone deacetylation.	EZH2 HDAC1	7.66e-05	5	97	2	10581039
Pubmed	Loss of BETA2/NeuroD leads to malformation of the dentate gyrus and epilepsy.	NEUROD1 NEUROD6	7.66e-05	5	97	2	10639171
Pubmed	The Polycomb Ezh2 methyltransferase regulates muscle gene expression and skeletal muscle differentiation.	EZH2 HDAC1	7.66e-05	5	97	2	15520282
Pubmed	Corepressor protein CDYL functions as a molecular bridge between polycomb repressor complex 2 and repressive chromatin mark trimethylated histone lysine 27.	EZH2 CBX2	7.66e-05	5	97	2	22009739
Pubmed	INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylases.	NEUROD1 HDAC1	7.66e-05	5	97	2	16569215
Pubmed	Characterization of erasin (UBXD2): a new ER protein that promotes ER-associated protein degradation.	CANX VCP	7.66e-05	5	97	2	16968747
Pubmed	The NuRD component Mbd3 is required for pluripotency of embryonic stem cells.	MTA1 HDAC1	7.66e-05	5	97	2	16462733
Pubmed	Arl13b in primary cilia regulates the migration and placement of interneurons in the developing cerebral cortex.	MAPT NEUROD6	7.66e-05	5	97	2	23153492
Pubmed	Epigenetic silencing of myogenic gene program by Myb-binding protein 1a suppresses myogenesis.	EZH2 HDAC1	7.66e-05	5	97	2	22333916
Interaction	TOP1 interactions	CDK8 RSF1 BUD13 CCDC12 ARID1A EZH2 APLF DHX8 PPP1R8 ZC3H11A MTA1 HNRNPUL2 NOP2 VCP CBX2	8.67e-07	696	95	15	int:TOP1
Interaction	SNRNP40 interactions	RSF1 NOC3L BUD13 NOL10 CCDC12 ARID1A DHX8 ARID3B PPP1R8 PRDM10 MTA1 HNRNPUL2 VCP CBX2	1.66e-06	637	95	14	int:SNRNP40
Interaction	POLR1G interactions	RSF1 NOC3L BUD13 CHD2 NOL10 ARID3B POLR3E NOP2 GPN3 HDAC1 CBX2	1.91e-05	489	95	11	int:POLR1G
Interaction	SSRP1 interactions	RSF1 CHD2 ARID1A EZH2 APLF PPP1R8 ZC3H11A MTA1 POLR3E HNRNPUL2 ROBO2 NOP2 CBX2	1.94e-05	685	95	13	int:SSRP1
Interaction	HIC1 interactions	ARID1A EZH2 MTA1 HDAC1	2.43e-05	36	95	4	int:HIC1
Interaction	SNIP1 interactions	NOC3L BUD13 NOL10 CCDC12 ARID1A EZH2 DHX8 HNRNPUL2 RRP9 NOP2	2.73e-05	417	95	10	int:SNIP1
Interaction	LIN28A interactions	NOC3L BUD13 NOL10 EZH2 DHX8 PRDM10 ZC3H11A HNRNPUL2 RRP9 NOP2	2.96e-05	421	95	10	int:LIN28A
Interaction	EED interactions	PUF60 NOC3L CHD2 NOL10 HS1BP3 ARID1A EZH2 PPP1R7 PPP1R8 ZC3H11A MTA1 HNRNPUL2 PPM1F RRP9 PALM3 GMFB NOP2 VCP HDAC1	3.77e-05	1445	95	19	int:EED
Interaction	LINC00839 interactions	SYNE1 FAM13B IRX4 BFSP1 PALM3	4.55e-05	83	95	5	int:LINC00839
Interaction	CENPA interactions	ERCC5 RSF1 NOC3L NOL10 ARID3B MTA1 NOP2 HDAC1 CBX2	7.27e-05	377	95	9	int:CENPA
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	MAPT PPP1R17 PPP1R7 PPP1R8 SLC9A1 PPP1R1B PPP1R3F	3.83e-06	181	65	7	694
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	FRMD6 MYO15A EPB41	7.70e-04	50	65	3	1293
GeneFamily	PHD finger proteins\|NuRD complex	MTA1 HDAC1	8.21e-04	12	65	2	1305
GeneFamily	AT-rich interaction domain containing	ARID1A ARID3B	1.30e-03	15	65	2	418
GeneFamily	Phosphodiesterases	PDE4B PDE6B	3.34e-03	24	65	2	681
GeneFamily	TALE class homeoboxes and pseudogenes	IRX3 IRX4	3.91e-03	26	65	2	526
GeneFamily	Zinc fingers CCCH-type	ZC3H11B ZC3H11A	7.02e-03	35	65	2	73
GeneFamily	Basic helix-loop-helix proteins	NEUROD4 NEUROD1 NEUROD6	7.28e-03	110	65	3	420
Coexpression	GSE17721_CTRL_VS_PAM3CSK4_12H_BMDC_DN	PDE4B ZDHHC5 IRX3 BFSP1 FRMD6 TSHZ1 GPN3	9.44e-06	199	97	7	M3750
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_500	CALD1 NEUROD4 CHD2 PPP1R17 ZC3H11A NEUROD1 HOXC8 ROBO2 DEPDC5 RPGR	1.45e-05	417	93	10	gudmap_developingGonad_e11.5_ovary + mesonephros_500
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CALD1 SYNE1 DZIP1 KCNB2 FRMD6 ROBO2 TSHZ1	2.55e-07	199	96	7	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	COVID-19-kidney-Lymphatic_EC\|kidney / Disease (COVID-19 only), tissue and cell type	PDE4B CALD1 ZNF521 FRMD6 PPM1F RPGR	1.68e-06	167	96	6	97d0fea1f41c1c00e36d9b5c4c1f0dd85087056f
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CALD1 SYNE1 DZIP1 FRMD6 ROBO2 TSHZ1	4.76e-06	200	96	6	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	CALD1 DZIP1 KCNB2 FRMD6 ROBO2 TSHZ1	4.76e-06	200	96	6	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Neuron\|1m / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 RTN4 PPP1R17 NEUROD1 NEUROD6 EPB41	4.76e-06	200	96	6	be1e153119ca4946b4eaef6037e8465f5c00ca6f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Cortical_neuron\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	MAPT SYNE1 NAP1L3 PPP1R1B PDGFC NEUROD6	4.76e-06	200	96	6	44bc4d6616fc8d0ad8498e56125939034e8cff01
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Neuron\|3m / Sample Type, Dataset, Time_group, and Cell type.	CALD1 NEUROD4 PPP1R17 PTMS NEUROD1 ROBO2	4.76e-06	200	96	6	3d134ae3c48ff4d1849db4fbe44ff73fb6c8c779
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CALD1 SYNE1 DZIP1 FRMD6 ROBO2 PDGFC	4.76e-06	200	96	6	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DCDC2 BTBD3 NEUROD1 TSHZ1 NEUROD6	2.75e-05	163	96	5	1e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	DCDC2 BTBD3 NEUROD1 TSHZ1 NEUROD6	2.75e-05	163	96	5	431221a41d396b09170476179590eaf8a55266d8
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CALD1 SYNE1 CAPN3 PTMS HOXC8	4.19e-05	178	96	5	0fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CCDC174 CAPN3 IRX3 STK11IP PRDM10	4.53e-05	181	96	5	709e9c7a60d5f98635b99895ce30bb87a9f7376d
ToppCell	Mesenchymal_cells-Ng2+_MSCs\|Mesenchymal_cells / Lineage and Cell class	CCDC12 TFR2 HIVEP3 ROBO2 PDGFC	5.29e-05	187	96	5	e899b906409f3fad69cb3d3c6432c3fd862ae3c1
ToppCell	Control-Fibroblasts-Other_FB\|Control / group, cell type (main and fine annotations)	CALD1 ZNF521 KCNB2 FRMD6 ROBO2	5.29e-05	187	96	5	bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	CALD1 NEUROD4 PPP1R17 NEUROD1 ROBO2	5.85e-05	191	96	5	48cffb55c71bb8b34e926fc461fcd345ce43ea00
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3_mon-IPC_like-IPCs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	CALD1 NEUROD4 PPP1R17 NEUROD1 ROBO2	5.85e-05	191	96	5	e4c1c533771b582e21683dbec6f93a558d865e00
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like-IPCs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	CALD1 NEUROD4 PPP1R17 NEUROD1 ROBO2	6.14e-05	193	96	5	2088f1d210c73f74685492c63065c62ac3f553e9
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	CALD1 NEUROD4 PPP1R17 NEUROD1 ROBO2	6.14e-05	193	96	5	f24bae40f5cbcfece04fbefe4e3de1b88ac90de4
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-IPC_like\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	CALD1 NEUROD4 PPP1R17 NEUROD1 ROBO2	6.30e-05	194	96	5	3e90be6f5b1c5c83632e62941fb18d6a627ec1b5
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-IPC_like-IPCs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	CALD1 NEUROD4 PPP1R17 PTMS ROBO2	6.45e-05	195	96	5	da8680a91648843901e456b5faef5e85039ade15
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-IPC_like-IPCs/Immature_PNs\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	CALD1 NEUROD4 PPP1R17 NEUROD1 ROBO2	6.45e-05	195	96	5	5e36a881fe2646f5a95d07d7b9265e6ada38730c
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	CALD1 NEUROD4 RSF1 PPP1R17 ROBO2	6.61e-05	196	96	5	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	CALD1 NEUROD4 RSF1 PPP1R17 ROBO2	6.61e-05	196	96	5	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CCDC184 MAPT NAP1L3 ZNF521 IRX3	6.61e-05	196	96	5	0767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CALD1 EZH2 PTMS ROBO2 TSHZ1	6.77e-05	197	96	5	29b0a5927f80455eef7b793feabef69fba1a3df1
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CALD1 NEUROD4 PPP1R17 NEUROD1 NEUROD6	6.93e-05	198	96	5	6d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	CALD1 NEUROD4 PPP1R17 NEUROD1 NEUROD6	6.93e-05	198	96	5	7943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CALD1 DZIP1 FRMD6 ROBO2 TSHZ1	7.10e-05	199	96	5	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	PPP1R17 NEUROD1 PPP1R1B NEUROD6 CBX2	7.10e-05	199	96	5	8e72efcd421639ac36ed036ee13f13de070d361f
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	MAPT NAP1L3 NEUROD1 PDGFC NEUROD6	7.27e-05	200	96	5	e9eb348a66011d8aace4331f84690ae27cb0d061
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	PPP1R17 NEUROD1 PPP1R1B NEUROD6 CBX2	7.27e-05	200	96	5	7c495030e6566b81d97b5516d1972e335ce5ed8c
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CALD1 SYNE1 DZIP1 FRMD6 ROBO2	7.27e-05	200	96	5	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	CALD1 SYNE1 DZIP1 FRMD6 ROBO2	7.27e-05	200	96	5	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CALD1 DZIP1 FRMD6 ROBO2 TSHZ1	7.27e-05	200	96	5	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	MAPT NAP1L3 NEUROD1 PDGFC NEUROD6	7.27e-05	200	96	5	09fd3cb31bcc02444f1045f01fe39bce09359d35
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	CALD1 SYNE1 ROBO2 TSHZ1 PDGFC	7.27e-05	200	96	5	593bf6a7c557437db9a9249a5058a46014179ef6
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CALD1 SYNE1 FRMD6 TSHZ1 PDGFC	7.27e-05	200	96	5	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CALD1 SYNE1 DZIP1 FRMD6 ROBO2	7.27e-05	200	96	5	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Neuron\|5w / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 RTN4 PTMS NEUROD1 EPB41	7.27e-05	200	96	5	6f3fe94107fa2a2ded4888780b36700cce48adb7
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic\|LPS_only / Treatment groups by lineage, cell group, cell type	CALD1 SYNE1 DZIP1 ROBO2 TSHZ1	7.27e-05	200	96	5	02cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	NEUROD4 PTMS NEUROD1 NEUROD6 EPB41	7.27e-05	200	96	5	332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Neuron\|2m / Sample Type, Dataset, Time_group, and Cell type.	CALD1 NEUROD4 PPP1R17 NEUROD1 NEUROD6	7.27e-05	200	96	5	a581f1704a87b0390e1e2ff85053367d85247755
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CALD1 SYNE1 ZNF521 FRMD6 ROBO2	7.27e-05	200	96	5	58b38f9a484ee94191091a0659ed62ebed2d4a14
Computational	Neighborhood of BAG5	PUF60 CANX PPP1R7 GMFB VCP	1.63e-05	55	63	5	MORF_BAG5
Computational	Neighborhood of PPP1CA	PUF60 CANX PPP1R7 TAF11 VCP HDAC1	4.34e-04	168	63	6	MORF_PPP1CA
Computational	Neighborhood of PSMC2	PUF60 CANX PPP1R7 GMFB VCP	5.51e-04	115	63	5	MORF_PSMC2
Computational	Neighborhood of RAB6A	CANX RTN4 PPP1R7 MTA1	6.23e-04	67	63	4	MORF_RAB6A
Computational	Neighborhood of RAD21	PUF60 CANX PPP1R7 MTA1 GMFB TAF11	6.25e-04	180	63	6	MORF_RAD21
Drug	Cefalonium [5575-21-3]; Down 200; 8.8uM; PC3; HT_HG-U133A	DCAF15 PDE4B CALD1 MAPT BFSP1 PTMS SLC9A1 MYO15A	1.62e-06	193	96	8	4245_DN
Disease	disease by infectious agent (is_implicated_in)	ERCC5 SERPIND1	2.94e-05	3	93	2	DOID:0050117 (is_implicated_in)
Disease	peptic ulcer disease, Peptic ulcer and gastro-oesophageal reflux disease (GORD) drug use measurement, gastroesophageal reflux disease	PDE4B KCNB2 DEPDC5	5.85e-05	24	93	3	EFO_0003948, EFO_0009923, MONDO_0004247
Disease	arthrogryposis multiplex congenita (is_implicated_in)	SYNE1 VPS33B	5.87e-05	4	93	2	DOID:0080954 (is_implicated_in)
Disease	body mass index, fasting blood insulin measurement	ZC3H11B TAF11 PDGFC	1.54e-04	33	93	3	EFO_0004340, EFO_0004466
Disease	S-6-hydroxywarfarin measurement	CDK8 ABCA4 NOL10 KCNB2 ROBO2 PDGFC NAA16	1.67e-04	368	93	7	EFO_0803326
Disease	myoclonic-atonic epilepsy (implicated_via_orthology)	CHD2 ROBO2	2.04e-04	7	93	2	DOID:0060475 (implicated_via_orthology)
Disease	Primary Progressive Nonfluent Aphasia	MAPT VCP	2.72e-04	8	93	2	C0751706
Disease	Behavioral variant of frontotemporal dementia	MAPT VCP	3.49e-04	9	93	2	C4011788
Disease	Umbilical hernia	CALD1 ZC3H11B	5.31e-04	11	93	2	HP_0001537
Disease	frontotemporal dementia (implicated_via_orthology)	MAPT VCP	6.35e-04	12	93	2	DOID:9255 (implicated_via_orthology)
Disease	dementia (is_implicated_in)	MAPT VCP	6.35e-04	12	93	2	DOID:1307 (is_implicated_in)
Disease	response to phenylephrine	PDE4B NEK11	1.30e-03	17	93	2	EFO_0010152
Disease	muscular dystrophy (is_implicated_in)	SYNE1 CAPN3	1.30e-03	17	93	2	DOID:9884 (is_implicated_in)
Disease	fasting blood insulin measurement	ZC3H11B TAF11 PDGFC	1.37e-03	69	93	3	EFO_0004466
Disease	stomach cancer (is_implicated_in)	ERCC5 ARID1A EZH2	1.54e-03	72	93	3	DOID:10534 (is_implicated_in)
Disease	cancer (implicated_via_orthology)	ARID1A FRMD6 DEPDC5 NOP2 CBX2	1.61e-03	268	93	5	DOID:162 (implicated_via_orthology)
Disease	Retinitis pigmentosa	ABCA4 PDE6B RPGR	1.67e-03	74	93	3	cv:C0035334
Disease	Colorectal Carcinoma	TBX22 ABCA4 SYNE1 RTN4 KCNB2 ARID1A HIVEP3 PPM1F	1.70e-03	702	93	8	C0009402
Disease	diet measurement	PDE4B RTN4 ZNF521 CHD2 CCDC12 APLF ASCC2 ROBO2 DEPDC5 IL27	1.73e-03	1049	93	10	EFO_0008111
Disease	Cleft palate, cleft lip	ABCA4 ARID3B ROBO2 DEPDC5 IL27	1.92e-03	279	93	5	EFO_0003959, HP_0000175
Disease	Retinal Degeneration	PDE6B RPGR	1.98e-03	21	93	2	C0035304
Disease	Nasopharyngeal carcinoma	SYNE1 ARID1A	2.18e-03	22	93	2	C2931822
Disease	Intrahepatic Cholangiocarcinoma	ARID1A ROBO2	2.59e-03	24	93	2	C0345905
Disease	Extrahepatic Cholangiocarcinoma	ARID1A ROBO2	2.59e-03	24	93	2	C3805278
Disease	influenza A (H1N1)	NEUROD4 BUD13 CFAP74	2.65e-03	87	93	3	EFO_1001488
Disease	Cholangiocarcinoma	ARID1A ROBO2	3.04e-03	26	93	2	C0206698

Protein segments in the cluster

Peptide	Gene	Start	Entry
ELDGDPERKEFLDDL	ARID3B	211	Q8IVW6
ELREDPDFEIKEGEG	EPB41	161	P11171
LEKEEEEDDGDLPVV	BUD13	66	Q9BRD0
EPGKEDEEKEDVEEL	APLF	486	Q8IW19
KEPIVDEDDDVAEER	ABCA4	1911	P78363
KVPREGQEEDDDDEE	ASCC2	651	Q9H1I8
LSKKAGPEEEEEEEE	GZF1	291	Q9H116
ELAEDKDEIRIPDVE	BTBD3	156	Q9Y2F9
EEEGGEEEAREEPLK	IRX4	226	P78413
DEEKRGAEEEEVEEP	PALM3	471	A6NDB9
PEGEEDDDYLDLEKI	SERPIND1	71	P05546
DERFGLEDPEDDICK	PDGFC	91	Q9NRA1
EELLGPKLEEEEEEE	ARID1A	1766	O14497
DLLPEADIDRRDEDG	DEPDC5	776	O75140
EESGDEDEDDPDKRI	HDAC1	391	Q13547
DIAELEEPEDAGVER	MYO15A	431	Q9UKN7
EKDDDIEEGDLPEHK	MESD	71	Q14696
DEKLEHIEELPEEGA	FAM13B	241	Q9NYF5
GARPEEEKEEEELGT	FER1L4	486	A9Z1Z3
DDPEEREEKQKDLED	EZH2	191	Q15910
ELTLDEEDSEGPEKE	PDE4B	681	Q07343
DEDELGEILKEELPG	PDE6B	481	P35913
EEEEASGLKEELIPE	NAA16	631	Q6N069
KREEDEPEERSGDET	HNRNPUL2	151	Q1KMD3
DEEEEEIALERPEKE	NEK11	491	Q8NG66
KAEEDEEAERILPGI	KLHL40	291	Q2TBA0
PLGRLEAKEEEDEDE	PRDM10	126	Q9NQV6
QQELREKEEEEEPEG	NOL10	526	Q9BSC4
RLVDHPDDEEEKEED	PPP4R3C	796	Q6ZMV5
GGKDRLEEDLQDDEI	FRMD6	441	Q96NE9
DDEDFLELPGAREEK	KCNB2	811	Q92953
AEESLEEEEALDPLG	HS1BP3	191	Q53T59
EDLEFKEPKEREDES	GPN3	256	Q9UHW5
DEEDDSDLDAKRGPR	CBX2	121	Q14781
AEDLFKELEGEESEP	CHD2	976	O14647
AELEGPEEKREGEER	BFSP1	551	Q12934
EEEEEERKGLLPGAL	IL27	171	Q8NEV9
EEEDRKPKAEEDEIL	CANX	566	P27824
DKLPGARDEEKVEEE	HOXC8	211	P31273
KAGERDDDEENLPEG	CCDC174	136	Q6PII3
DGEPKTKHLREEEEE	CCDC12	36	Q8WUD4
EEDELEEEPRSTGEL	GRAMD2A	291	Q8IUY3
RLKLLEEDDDPDDSE	CAPN3	461	P20807
REFLTEEEPDDKGDK	CDK8	356	P49336
QSLKDGEERGEEDPE	PPP1R7	46	Q15435
EEEEEEEGKPSRKRL	RSF1	1286	Q96T23
GAPEEEEDELLRVTD	RSF1	1416	Q96T23
RIKEEPVSEEGEEDE	POLR3E	496	Q9NVU0
LGRDPEDEEEEEEEK	CCDC184	131	Q52MB2
EDERDELEDPEFDIK	CFAP74	21	Q9C0B2
GTEPEDELEDDKISL	DCAF15	401	Q66K64
QRPAEIVDEEEDGEK	DCDC2	341	Q9UHG0
EETGILPKVDDEEDE	DHX8	421	Q14562
RKLPREEEEEEEDDD	PPM1F	96	P49593
DGKRELELEEEELGG	IRX3	221	P78415
IEREEEEEEEALPLD	NOC3L	76	Q8WTT2
DRLSEIPEEKEGAED	RPGR	786	Q92834
DEELEGISPDELKDE	GMFB	46	P60983
DEDLEELEVLERKPA	RTN4	46	Q9NQC3
RAEPQEEEEEKEGKE	STK11IP	491	Q8N1F8
DLEIDKEGVIEPDTD	ST13P4	76	Q8IZP2
EDDELKGLLGLPEEE	PPP1R8	146	Q12972
DPKDIDDDLEGEVTE	PUF60	471	Q9UHX1
LVLRGPDETKEEEED	RSAD2	51	Q8WXG1
RALPSEDEEGQDDKD	SYNE1	8301	Q8NF91
IPEETDGDADVDLKE	TAF11	36	Q15544
DERAIADKPGEDAEA	ITIH3	611	Q06033
ERDDVDGEPQEAEKD	ERCC5	706	P28715
IGKLEPREDAILDED	NAP1L3	451	Q99457
DITDLLKEGEEDGRD	MTA1	176	Q13330
EDEEEGEALLPIERA	NOP2	151	P46087
LEPIEELSEEEKGRE	DZIP1	501	Q86YF9
EEEEEEKPKRGSIGE	CALD1	191	Q05682
LLEEEEEDLEGKEEG	RINL	231	Q6ZS11
DERPKAIVEDDEKDG	PPP1R17	136	O96001
GEPIKREDEEESLNE	VCP	186	P55072
RKPEEEEEEELEETA	RRP9	61	O43818
EEDDEGPALKRAAEE	PTMS	71	P20962
GPALKRAAEEEDEAD	PTMS	76	P20962
EQPELREKKGGEEEE	TBX22	31	Q9Y458
CKKRPEDGEELEDEA	ZNF521	31	Q96K83
EAEIDLDPGKDEDDL	ZC3H11A	786	O75152
EKEEERRGEPEEDAP	HIVEP3	1706	Q5T1R4
RDPAKVAEEDEDDDG	SLC9A1	746	P19634
RPGSKEEVDEDRDVD	MAPT	211	P10636
GRGVELIKDTEDPDD	PPP1R3F	561	Q6ZSY5
QGLEDELEEDDDRVP	ROBO2	1116	Q9HCK4
LEAEIDLDPGKDEDD	ZC3H11B	786	A0A1B0GTU1
GIFPRAEEDEDKEDD	ZDHHC5	71	Q9C0B5
LRELGYPREEDEEEE	PPP1R1B	111	Q9UD71
VEGPRKGHLEEEEED	TFR2	26	Q9UP52
FDLRDDDDAEEEGPK	TCF25	26	Q9BQ70
DDDAEEEGPKRELGV	TCF25	31	Q9BQ70
LEKDLEEDREENPGL	ZSCAN5C	221	A6NGD5
LREEDLDDSPKGGLD	TSHZ1	536	Q6ZSZ6
EEEEDGETKGRRPEI	VPS33B	211	Q9H267
TVLEDLERELDDPGE	ZSCAN23	121	Q3MJ62
EEEEEDDDQKPKRRG	NEUROD1	71	Q13562
EEEEEEEDGEKPKRR	NEUROD4	56	Q9HD90
APGEETEKEEEEEDR	NEUROD6	51	Q96NK8