Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cysteine-type deubiquitinase activity	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L15 USP17L8 USP17L13 USP17L18	2.51e-26	114	78	19	GO:0004843
GeneOntologyMolecularFunction	deubiquitinase activity	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L15 USP17L8 USP17L13 USP17L18	1.38e-25	124	78	19	GO:0101005
GeneOntologyMolecularFunction	ubiquitin-like protein peptidase activity	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L15 USP17L8 USP17L13 USP17L18	1.02e-24	137	78	19	GO:0019783
GeneOntologyMolecularFunction	cysteine-type peptidase activity	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L15 USP17L8 USP17L13 USP17L18	7.85e-22	192	78	19	GO:0008234
GeneOntologyMolecularFunction	peptidase activity	HGF USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X F10 USP17L15 ADAMTSL2 USP17L8 USP17L13 USP17L18	3.88e-15	654	78	22	GO:0008233
GeneOntologyMolecularFunction	pre-mRNA 3'-splice site binding	ZRSR2P1 ZRSR2	3.12e-04	7	78	2	GO:0030628
GeneOntologyBiologicalProcess	protein deubiquitination	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L15 USP17L8 USP17L13 USP17L18	5.09e-26	125	76	19	GO:0016579
GeneOntologyBiologicalProcess	protein modification by small protein removal	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L15 USP17L8 USP17L13 USP17L18	8.68e-25	144	76	19	GO:0070646
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	USP17L21 USP17L4 AMER1 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 PHRF1 USP17L3 USP17L5 USP17L10 USP17L19 MDM2 USP17L22 USP27X USP17L15 USP17L8 USP17L13 USP17L18	6.86e-12	1009	76	22	GO:0070647
GeneOntologyBiologicalProcess	post-translational protein modification	USP17L21 USP17L4 AMER1 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 PHRF1 USP17L3 USP17L5 USP17L10 USP17L19 MDM2 USP17L22 USP27X USP17L15 USP17L8 USP17L13 USP17L18	2.32e-11	1074	76	22	GO:0043687
GeneOntologyCellularComponent	endoplasmic reticulum membrane	USP17L21 ESYT2 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 ATP10A USP17L15 USP17L8 USP17L13 USP17L18	1.55e-07	1293	77	19	GO:0005789
GeneOntologyCellularComponent	endoplasmic reticulum subcompartment	USP17L21 ESYT2 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 ATP10A USP17L15 USP17L8 USP17L13 USP17L18	1.66e-07	1299	77	19	GO:0098827
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	USP17L21 ESYT2 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 ATP10A USP17L15 USP17L8 USP17L13 USP17L18	2.31e-07	1327	77	19	GO:0042175
GeneOntologyCellularComponent	U2AF complex	ZRSR2P1 ZRSR2	2.78e-04	7	77	2	GO:0089701
MousePheno	increased trophectoderm apoptosis	USP17L2 USP17L15 USP17L13	2.38e-06	8	50	3	MP:0012119
MousePheno	abnormal thymus weight	USP17L2 MDM2 USP17L15 USP17L13	6.09e-05	60	50	4	MP:0004954
MousePheno	increased thymus weight	USP17L2 USP17L15 USP17L13	8.27e-05	24	50	3	MP:0004955
Domain	HABP4_PAI-RBP1	USP17L21 USP17L2 USP17L12 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L19 USP17L22 USP17L13 USP17L18	1.57e-29	16	76	13	PF04774
Domain	HABP4_PAIRBP1-bd	USP17L21 USP17L2 USP17L12 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L19 USP17L22 USP17L13 USP17L18	1.57e-29	16	76	13	IPR006861
Domain	UCH	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L8 USP17L13 USP17L18	2.81e-28	71	76	18	PF00443
Domain	USP_2	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L8 USP17L13 USP17L18	2.81e-28	71	76	18	PS00973
Domain	USP_3	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L8 USP17L13 USP17L18	3.74e-28	72	76	18	PS50235
Domain	USP_dom	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L8 USP17L13 USP17L18	3.74e-28	72	76	18	IPR028889
Domain	Peptidase_C19_UCH	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L8 USP17L13 USP17L18	3.74e-28	72	76	18	IPR001394
Domain	USP_CS	USP17L21 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L8 USP17L13 USP17L18	7.27e-27	66	76	17	IPR018200
Domain	USP_1	USP17L21 USP17L4 USP17L2 USP17L12 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP27X USP17L8 USP17L13 USP17L18	2.25e-26	70	76	17	PS00972
Domain	U2AF_small	ZRSR2P1 ZRSR2	1.62e-04	5	76	2	IPR009145
Domain	Znf_FYVE_PHD	KMT2D PCLO PHRF1 KDM4A SP110	3.33e-04	147	76	5	IPR011011
Domain	PHD	KMT2D PHRF1 KDM4A SP110	4.76e-04	89	76	4	SM00249
Domain	Znf_PHD	KMT2D PHRF1 KDM4A SP110	5.18e-04	91	76	4	IPR001965
Domain	ZF_PHD_2	KMT2D PHRF1 KDM4A SP110	6.09e-04	95	76	4	PS50016
Domain	ZF_PHD_1	KMT2D PHRF1 KDM4A SP110	6.34e-04	96	76	4	PS01359
Domain	Cyclophilin-type_PPIase_CS	PPIG NKTR	2.67e-03	19	76	2	IPR020892
Domain	Cyclophilin-type_PPIase	PPIG NKTR	3.26e-03	21	76	2	IPR024936
Domain	PHD	KMT2D PHRF1 SP110	3.54e-03	75	76	3	PF00628
Domain	EPHD	KMT2D KDM4A	3.58e-03	22	76	2	PS51805
Domain	Cyclophilin-like_dom	PPIG NKTR	3.58e-03	22	76	2	IPR029000
Domain	CSA_PPIASE_2	PPIG NKTR	3.58e-03	22	76	2	PS50072
Domain	Pro_isomerase	PPIG NKTR	3.58e-03	22	76	2	PF00160
Domain	-	PPIG NKTR	3.58e-03	22	76	2	2.40.100.10
Domain	Cyclophilin-type_PPIase_dom	PPIG NKTR	3.58e-03	22	76	2	IPR002130
Domain	CSA_PPIASE_1	PPIG NKTR	3.58e-03	22	76	2	PS00170
Domain	RRM_dom_euk	ZRSR2 RBM39	3.91e-03	23	76	2	IPR003954
Domain	RRM_1	ZRSR2 RBM39	3.91e-03	23	76	2	SM00361
Domain	Znf_PHD-finger	KMT2D PHRF1 SP110	4.10e-03	79	76	3	IPR019787
Pathway	REACTOME_RAS_PROCESSING	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	2.96e-30	45	59	17	MM15671
Pathway	REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 MDM2 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.89e-20	221	59	19	M27578
Pathway	REACTOME_UB_SPECIFIC_PROCESSING_PROTEASES	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 MDM2 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	4.19e-20	191	59	18	MM15289
Pathway	REACTOME_DEUBIQUITINATION	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 MDM2 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	5.88e-18	299	59	19	M27574
Pathway	REACTOME_DEUBIQUITINATION	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 MDM2 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.28e-17	262	59	18	MM15286
Pathway	REACTOME_MAPK_FAMILY_SIGNALING_CASCADES	HGF USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 RAPGEF2 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.87e-17	318	59	19	MM15278
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	USP17L21 USP17L4 AMER1 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 MDM2 USP17L22 F10 USP17L15 ADAMTSL2 USP17L8 USP17L13 USP17L18	4.55e-08	1475	59	22	M19806
Pathway	REACTOME_POST_TRANSLATIONAL_PROTEIN_MODIFICATION	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 MDM2 USP17L22 F10 USP17L15 ADAMTSL2 USP17L8 USP17L13 USP17L18	4.21e-07	1389	59	20	MM15307
Pubmed	Minor Splicing Factors Zrsr1 and Zrsr2 Are Essential for Early Embryo Development and 2-Cell-Like Conversion.	USP17L21 ZRSR2P1 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 ZRSR2 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.10e-44	29	79	19	32527007
Pubmed	Decabromodiphenyl ethane affects embryonic development by interfering with nuclear F-actin in zygotes and leads to cognitive and social disorders in offspring mice.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 SP110 USP17L15 USP17L8 USP17L13 USP17L18	4.92e-43	26	79	18	35816173
Pubmed	DUB-1, a deubiquitinating enzyme with growth-suppressing activity.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.06e-42	21	79	17	8622927
Pubmed	DUB-1A, a novel deubiquitinating enzyme subfamily member, is polyubiquitinated and cytokine-inducible in B-lymphocytes.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.06e-42	21	79	17	14583620
Pubmed	DUB-2A, a new member of the DUB subfamily of hematopoietic deubiquitinating enzymes.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.06e-42	21	79	17	11468161
Pubmed	The murine DUB-1 gene is specifically induced by the betac subunit of interleukin-3 receptor.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.06e-42	21	79	17	8756639
Pubmed	Lymphocyte-specific murine deubiquitinating enzymes induced by cytokines.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.06e-42	21	79	17	12447969
Pubmed	DUB-1, a fate determinant of dynein heavy chain in B-lymphocytes, is regulated by the ubiquitin-proteasome pathway.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.06e-42	21	79	17	18980247
Pubmed	JAK2 is required for induction of the murine DUB-1 gene.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	4.68e-42	22	79	17	9154835
Pubmed	DUB-2 is a member of a novel family of cytokine-inducible deubiquitinating enzymes.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.13e-41	24	79	17	8995226
Pubmed	Interleukin 1 receptor signaling regulates DUBA expression and facilitates Toll-like receptor 9-driven antiinflammatory cytokine production.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.91e-40	25	79	17	21115691
Pubmed	Cdc25A and Dub3 in a high-stakes balancing act.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	3.23e-40	33	79	18	20228807
Pubmed	The DUB/USP17 deubiquitinating enzymes: a gene family within a tandemly repeated sequence, is also embedded within the copy number variable beta-defensin cluster.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.85e-40	34	79	18	20403174
Pubmed	Hyaluronan- and RNA-binding deubiquitinating enzymes of USP17 family members associated with cell viability.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.85e-40	34	79	18	17109758
Pubmed	The deubiquitinating enzyme USP17 is highly expressed in tumor biopsies, is cell cycle regulated, and is required for G1-S progression.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.85e-40	34	79	18	20388806
Pubmed	DUB-3, a cytokine-inducible deubiquitinating enzyme that blocks proliferation.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.85e-40	34	79	18	14699124
Pubmed	Polyclonal and monoclonal antibodies specific for USP17, a proapoptotic deubiquitinating enzyme.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.85e-40	34	79	18	20715989
Pubmed	Human megasatellite DNA RS447: copy-number polymorphisms and interspecies conservation.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.85e-40	34	79	18	9806828
Pubmed	The ubiquitin-specific protease 17 is involved in virus-triggered type I IFN signaling.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.85e-40	34	79	18	20368735
Pubmed	The DUB/USP17 deubiquitinating enzymes, a multigene family within a tandemly repeated sequence.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.85e-40	34	79	18	15780755
Pubmed	USP17 regulates Ras activation and cell proliferation by blocking RCE1 activity.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.85e-40	34	79	18	19188362
Pubmed	Unstable transmission of the RS447 human megasatellite tandem repetitive sequence that contains the USP17 deubiquitinating enzyme gene.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.85e-40	34	79	18	11941478
Pubmed	The RS447 human megasatellite tandem repetitive sequence encodes a novel deubiquitinating enzyme with a functional promoter.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.85e-40	34	79	18	10936051
Pubmed	The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	6.85e-40	34	79	18	21448158
Pubmed	Cytokine-regulated protein degradation by the ubiquitination system.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.41e-39	35	79	18	16611142
Pubmed	Lys-63-specific deubiquitination of SDS3 by USP17 regulates HDAC activity.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.41e-39	35	79	18	21239494
Pubmed	The deubiquitinating enzyme USP17 blocks N-Ras membrane trafficking and activation but leaves K-Ras unaffected.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	2.81e-39	36	79	18	20147298
Pubmed	Ubiquitin hydrolase Dub3 promotes oncogenic transformation by stabilizing Cdc25A.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	5.47e-39	37	79	18	20228808
Pubmed	DUX is a non-essential synchronizer of zygotic genome activation.	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 SP110 USP17L15 USP17L8 USP17L13 USP17L18	5.47e-36	50	79	18	31806660
Pubmed	USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.	ANKRD31 USP17L21 ZRSR2P1 USP17L4 CFAP91 KMT2D AMER1 USP17L2 USP17L12 USP17L1 USP17L17 ZRSR2 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 VSTM5 USP17L22 USP17L15 PREX2 USP17L8 USP17L13 USP17L18	9.21e-24	674	79	25	37196079
Pubmed	High Dub3 expression in mouse ESCs couples the G1/S checkpoint to pluripotency.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8	2.36e-14	10	79	6	24207026
Pubmed	Cell cycle-dependent expression of Dub3, Nanog and the p160 family of nuclear receptor coactivators (NCoAs) in mouse embryonic stem cells.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8	1.03e-13	12	79	6	24695638
Pubmed	ES cell neural differentiation reveals a substantial number of novel ESTs.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8	3.35e-13	14	79	6	11793228
Pubmed	CDK4/6-dependent activation of DUB3 regulates cancer metastasis through SNAIL1.	USP17L4 USP17L2 USP17L1 USP17L3 USP17L15 USP17L8	3.00e-12	19	79	6	28067227
Pubmed	Human and mouse proteases: a comparative genomic approach.	USP17L4 USP17L2 USP17L1 USP17L3 USP27X USP17L15 USP17L8	7.22e-10	81	79	7	12838346
Pubmed	A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.	USP17L21 USP17L12 USP17L17 USP17L20 USP17L11 USP17L19 USP17L18	1.09e-08	119	79	7	28625976
Pubmed	Embryonic demise caused by targeted disruption of a cysteine protease Dub-2.	USP17L2 USP17L15 USP17L13	4.50e-08	4	79	3	22984479
Pubmed	DNA sequence and analysis of human chromosome 8.	USP17L4 USP17L1 USP17L3 USP17L8	4.45e-06	48	79	4	16421571
Pubmed	ZRSR1 co-operates with ZRSR2 in regulating splicing of U12-type introns in murine hematopoietic cells.	ZRSR2P1 ZRSR2	5.09e-06	2	79	2	33691379
Pubmed	Zrsr2 and functional U12-dependent spliceosome are necessary for follicular development.	ZRSR2P1 ZRSR2	5.09e-06	2	79	2	35198906
Pubmed	RS cyclophilins: identification of an NK-TR1-related cyclophilin.	PPIG CLK1	5.09e-06	2	79	2	8973360
Pubmed	Multiple roles of beta-catenin in controlling the neurogenic niche for midbrain dopamine neurons.	PITX3 CTNNA1 PCNT	1.25e-05	20	79	3	19439492
Pubmed	Isolation and mapping of human homologues of an imprinted mouse gene U2af1-rs1.	ZRSR2P1 ZRSR2	1.53e-05	3	79	2	8586425
Pubmed	Concurrent Zrsr2 mutation and Tet2 loss promote myelodysplastic neoplasm in mice.	ZRSR2P1 ZRSR2	1.53e-05	3	79	2	36030305
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	PPIG AMER1 CLK1 CDK12 CDH23 ATP10A RBM39	1.87e-05	361	79	7	26167880
Pubmed	Mouse U2af1-rs1 is a neomorphic imprinted gene.	ZRSR2P1 ZRSR2	3.05e-05	4	79	2	9001233
Pubmed	Cloning and mapping of the U2af1-rs2 gene with a high transmission distortion in interspecific backcross progeny.	ZRSR2P1 ZRSR2	3.05e-05	4	79	2	7558001
Pubmed	Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition.	ZRSR2P1 ZRSR2	7.60e-05	6	79	2	33846634
Pubmed	SCFFBXO22 targets HDM2 for degradation and modulates breast cancer cell invasion and metastasis.	KDM4A MDM2	7.60e-05	6	79	2	31138683
Pubmed	Large-scale identification of mammalian proteins localized to nuclear sub-compartments.	ZRSR2P1 ZRSR2 PCNT	8.99e-05	38	79	3	11555636
Pubmed	A protein related to splicing factor U2AF35 that interacts with U2AF65 and SR proteins in splicing of pre-mRNA.	ZRSR2P1 ZRSR2	1.06e-04	7	79	2	9237760
Pubmed	Allelic variants between mouse substrains BALB/cJ and BALB/cByJ influence mononuclear cardiomyocyte composition and cardiomyocyte nuclear ploidy.	ZRSR2P1 ZRSR2	1.41e-04	8	79	2	32371981
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	SP2 PPIG ESYT2 RPL36 KMT2D PHRF1 GPATCH4 NKTR SP110 RBM39 PRDM2	1.61e-04	1294	79	11	30804502
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	ZRSR2P1 PPIG KMT2D CDK12 PCNT	2.74e-04	251	79	5	31076518
Pubmed	New nomenclature for chromatin-modifying enzymes.	KMT2D KDM4A PRDM2	3.02e-04	57	79	3	18022353
Pubmed	Telophase correction refines division orientation in stratified epithelia.	CTNNA1 PCNT	3.31e-04	12	79	2	31833472
Pubmed	Divergent regulation of functionally distinct γ-tubulin complexes during differentiation.	CTNNA1 PCNT	3.31e-04	12	79	2	27298324
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	PPIG ESYT2 KMT2D CDK12 SVIL PHRF1 CTNNA1 PRDM2	3.77e-04	774	79	8	15302935
Pubmed	A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.	HGF USP17L21 USP17L12 USP17L19 RBM39 PCNT	3.91e-04	419	79	6	28700943
Pubmed	The microRNA-200 family coordinately regulates cell adhesion and proliferation in hair morphogenesis.	CTNNA1 PCNT	4.55e-04	14	79	2	29602800
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	PPIG CDK12 CAVIN1 NKTR PCNT	4.90e-04	285	79	5	32838362
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	PPIG RPL36 AMER1 BTF3 SVIL ASCC2 GPATCH4 CTNNA1 RSRC2 RBM39	5.17e-04	1247	79	10	27684187
Pubmed	Long noncoding RNA PiHL regulates p53 protein stability through GRWD1/RPL11/MDM2 axis in colorectal cancer.	PCLO MDM2	5.25e-04	15	79	2	31903119
Pubmed	Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases.	PPIG NKTR	5.25e-04	15	79	2	20676357
Pubmed	Proteomic analysis identifies that 14-3-3zeta interacts with beta-catenin and facilitates its activation by Akt.	BTF3 CTNNA1	5.25e-04	15	79	2	15492215
Pubmed	Dephosphorylation of the transcriptional cofactor NACA by the PP1A phosphatase enhances cJUN transcriptional activity and osteoblast differentiation.	BTF3 SVIL	5.25e-04	15	79	2	30948508
Pubmed	Cell-free cotranslation and selection using in vitro virus for high-throughput analysis of protein-protein interactions and complexes.	TRO MDM2	5.99e-04	16	79	2	15867431
Pubmed	The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex.	ANKRD31 PCLO SVIL	6.01e-04	72	79	3	33726789
Pubmed	Comparative mapping of the imprinted U2afbpL gene on mouse chromosome 11 and human chromosome 5.	ZRSR2P1 ZRSR2	6.78e-04	17	79	2	7956352
Pubmed	Screening E3 substrates using a live phage display library.	MDM2 PRDM2	6.78e-04	17	79	2	24124579
Pubmed	Transcriptomic and genetic studies identify IL-33 as a candidate gene for Alzheimer's disease.	ZRSR2 PITX3 PCNT	7.59e-04	78	79	3	19204726
Pubmed	alphaE-catenin controls cerebral cortical size by regulating the hedgehog signaling pathway.	CTNNA1 PCNT	8.50e-04	19	79	2	16543460
Pubmed	Targeted inactivation of MLL3 histone H3-Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis.	KMT2D ASCC2	9.43e-04	20	79	2	19047629
Pubmed	The protein interaction landscape of the human CMGC kinase group.	PPIG ESYT2 ZRSR2 CLK1 CDK12 RSRC2 RBM39	1.03e-03	695	79	7	23602568
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KMT2D KDM4A	1.04e-03	21	79	2	27626377
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	ANKRD36B PPIG RRAGD CDK12 SVIL ASCC2 GPATCH4 CAVIN1 NKTR RSRC2	1.07e-03	1371	79	10	36244648
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	ANKRD36B CLK1 CDK12 SH3PXD2A TTC14 NKTR ANKRD36C USP27X	1.08e-03	910	79	8	36736316
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	PPIG RPL36 CDK12 GPATCH4 NKTR RSRC2 RBM39	1.19e-03	713	79	7	29802200
Pubmed	Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.	SVIL CTNNA1 MDM2	1.34e-03	95	79	3	35896951
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	SP2 SVIL RSRC2 RAPGEF2 MDM2	1.59e-03	371	79	5	15747579
Pubmed	Dual function of Yap in the regulation of lens progenitor cells and cellular polarity.	CTNNA1 PCNT	1.60e-03	26	79	2	24384391
Pubmed	Epidermal development requires ninein for spindle orientation and cortical microtubule organization.	CTNNA1 PCNT	1.60e-03	26	79	2	30923192
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ESYT2 CDK12 PPP1R16B PCNT	1.75e-03	225	79	4	12168954
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	PCLO ATP10A ADAMTSL2	1.79e-03	105	79	3	9628581
Pubmed	Novel interactors and a role for supervillin in early cytokinesis.	SH3PXD2A SVIL	1.85e-03	28	79	2	20309963
Pubmed	The Tumor Suppressor SASH1 Interacts With the Signal Adaptor CRKL to Inhibit Epithelial-Mesenchymal Transition and Metastasis in Colorectal Cancer.	ASCC2 CTNNA1	2.13e-03	30	79	2	30480076
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	SP2 KMT2D PCLO ZNF518B PRDM2	2.16e-03	398	79	5	35016035
Pubmed	miR-218 Promotes Dopaminergic Differentiation and Controls Neuron Excitability and Neurotransmitter Release through the Regulation of a Synaptic-Related Genes Network.	PCLO PITX3	2.27e-03	31	79	2	37816598
Interaction	SRRM4 interactions	ZRSR2P1 ZRSR2 CLK1 RBM39	1.01e-05	37	74	4	int:SRRM4
Interaction	DHX8 interactions	RPL36 CDK12 PHRF1 TTC14 GPATCH4 NKTR RSRC2 RBM39	1.16e-05	292	74	8	int:DHX8
Interaction	CLK1 interactions	PPIG ZRSR2 CLK1 CDK12 CDH23 ATP10A RBM39	1.58e-05	219	74	7	int:CLK1
Interaction	ZCCHC10 interactions	ANKRD36B PPIG ELOA2 CDK12 CAVIN1 NKTR RBM39	2.55e-05	236	74	7	int:ZCCHC10
Cytoband	4p16.1	USP17L21 USP17L12 USP17L17 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 ZNF518B USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	6.72e-25	79	79	14	4p16.1
Cytoband	Ensembl 112 genes in cytogenetic band chr4p16	USP17L21 USP17L12 USP17L17 USP17L20 USP17L11 USP17L24 USP17L5 USP17L10 ZNF518B USP17L19 USP17L22 USP17L15 USP17L13 USP17L18	2.38e-18	222	79	14	chr4p16
Cytoband	8p23.1	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	7.34e-06	154	79	5	8p23.1
Cytoband	Ensembl 112 genes in cytogenetic band chr8p23	USP17L4 USP17L2 USP17L1 USP17L3 USP17L8	5.46e-05	234	79	5	chr8p23
GeneFamily	Cyclophilin peptidylprolyl isomerases	PPIG NKTR	1.10e-03	19	47	2	909
GeneFamily	PHD finger proteins	KMT2D PHRF1 SP110	1.65e-03	90	47	3	88
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	KMT2D PRDM2	3.52e-03	34	47	2	487
GeneFamily	Ankyrin repeat domain containing	ANKRD36B ANKRD31 PPP1R16B ANKRD36C	3.56e-03	242	47	4	403
GeneFamily	Zinc fingers CCCH-type	ZRSR2P1 ZRSR2	3.73e-03	35	47	2	73
GeneFamily	PDZ domain containing	PCLO RAPGEF2 PREX2	7.21e-03	152	47	3	1220
GeneFamily	Ubiquitin specific peptidases	USP17L2 USP27X	9.32e-03	56	47	2	366
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PHRF1 PPP1R16B PREX2	1.16e-02	181	47	3	694
Coexpression	MADAN_DPPA4_TARGETS	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	5.89e-27	86	78	17	MM1312
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_SERUM_DEPRIVATION_DN	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	7.51e-25	112	78	17	MM1095
Coexpression	GERY_CEBP_TARGETS	HGF USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	8.05e-24	160	78	18	MM1155
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_UP	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 MDM2 USP17L22 SP110 USP17L15 USP17L8 USP17L13 USP17L18	3.80e-14	647	78	19	MM981
Coexpression	GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 TTC16 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 CAVIN1 USP17L19 MDM2 USP17L22 USP27X SP110 USP17L15 USP17L8 USP17L13 USP17L18	5.26e-12	1226	78	22	MM979
Coexpression	MARSON_BOUND_BY_FOXP3_STIMULATED	USP17L21 USP17L4 ELOA2 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L3 USP17L5 USP17L10 USP17L19 MDM2 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	2.44e-10	1072	78	19	MM1031
Coexpression	BRUINS_UVC_RESPONSE_LATE	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 ASCC2 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.05e-08	1198	78	18	MM1062
Coexpression	NAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_3DY_DN	CLK1 CDK12 PPP1R16B NKTR RSRC2 RAPGEF2 RBM39 PRDM2	4.37e-05	432	78	8	M41149
CoexpressionAtlas	FacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3	ZRSR2 CDK12 PCLO TTC14 GPATCH4 ZNF518B RSRC2 PREX2 PCNT	1.98e-05	532	61	9	Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
ToppCell	H1299-infected-SARSCoV2\|infected / Cell line, Condition and Strain	PPIG ZRSR2 GPATCH4 NKTR ANKRD36C RSRC2 RBM39	3.21e-08	197	72	7	0fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	ANKRD36B ESYT2 CLK1 NKTR ANKRD36C RBM39	6.90e-07	192	72	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CLK1 NKTR RSRC2 SP110 RBM39 PRDM2	8.76e-07	200	72	6	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	KMT2D TTC14 NKTR ANKRD36C RBM39	4.08e-06	147	72	5	94998bc40f5c08295cfe3bdcbe43f13b1e564b3d
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL36 CLK1 PPP1R16B RSRC2 RBM39	1.15e-05	182	72	5	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	droplet-Spleen-nan-18m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL36 CLK1 PPP1R16B RSRC2 RBM39	1.18e-05	183	72	5	28cbf909424f3be4491d49832f0aca0386560814
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL36 CLK1 PPP1R16B RSRC2 RBM39	1.18e-05	183	72	5	3fa608aa6b119869ec3280dc388dfee57160e63a
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPIG CLK1 CDK12 RSRC2 RBM39	1.31e-05	187	72	5	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	NKTR ANKRD36C RAPGEF2 RBM39 PRDM2	1.35e-05	188	72	5	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	droplet-Tongue-nan\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPIG RPL36 CDK12 RSRC2 RBM39	1.35e-05	188	72	5	d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	CLK1 NKTR RSRC2 RBM39 PRDM2	1.45e-05	191	72	5	1ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HGF COL24A1 RPL36 BTF3 SPHKAP	1.57e-05	194	72	5	28c5482da199bcee9e85258a88af453d9fdbd56a
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK12 TTC14 RSRC2 PREX2 PRDM2	1.57e-05	194	72	5	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	(1)_T_cells-(1)_T_CD4_naive\|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ANKRD36B TTC14 NKTR ANKRD36C ATP10A	1.61e-05	195	72	5	d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature2_(2)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	HGF COL24A1 RPL36 BTF3 SPHKAP	1.73e-05	198	72	5	89e25687b614525548279e5fa293c66f5c4abec3
ToppCell	Healthy_donor\|World / disease group, cell group and cell class (v2)	RPL36 BTF3 TTC14 NKTR RBM39	1.73e-05	198	72	5	1ed0b50c9754727a05c27b21f3546bf2e37eef7f
ToppCell	mild-low-quality_cells\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	CLK1 TTC14 NKTR ANKRD36C RBM39	1.77e-05	199	72	5	f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell	Healthy/Control\|World / Disease group and Cell class	RPL36 BTF3 TTC14 NKTR RBM39	1.77e-05	199	72	5	2623c42b3e79e401a485879b52e8bbcbc581544d
ToppCell	COVID-19_Moderate\|World / disease group, cell group and cell class	ANKRD36B ZRSR2 NKTR ANKRD36C SP110	1.77e-05	199	72	5	952fac67588ad5676f5939e3c7f8bac803c27064
Disease	primary ovarian insufficiency (implicated_via_orthology)	USP17L21 USP17L4 USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	5.73e-36	46	75	18	DOID:5426 (implicated_via_orthology)
Disease	congenital heart disease (implicated_via_orthology)	USP17L21 USP17L4 KMT2D USP17L2 USP17L12 USP17L1 USP17L17 USP17L20 USP17L11 USP17L24 USP17L3 USP17L5 USP17L10 USP17L19 USP17L22 USP17L15 USP17L8 USP17L13 USP17L18	1.75e-34	69	75	19	DOID:1682 (implicated_via_orthology)
Disease	meningioma (is_marker_for)	HGF KMT2D	1.91e-05	3	75	2	DOID:3565 (is_marker_for)
Disease	biliary tract benign neoplasm (is_marker_for)	HGF MDM2	1.33e-04	7	75	2	DOID:0050625 (is_marker_for)
Disease	Microphthalmos	KMT2D PITX3	3.45e-04	11	75	2	C0026010
Disease	cytomegalovirus virus reactivation, response to allogeneic hematopoietic stem cell transplant	PCLO CDH23	1.06e-03	19	75	2	EFO_0007044, EFO_0020106
Disease	Hematopoetic Myelodysplasia	ZRSR2 CTNNA1	2.48e-03	29	75	2	C2713368

Protein segments in the cluster

Peptide	Gene	Start	Entry
RTRHRSDKKKSKGGI	PRPF4B	191	Q13523
PDKRRSGRRKTHVSK	ESYT2	831	A0FGR8
GKGTARRKKKVVHRT	BTF3	66	P20290
KSGHKDRSKSHRKRE	CDK12	191	Q9NYV4
TRHTLEKRMNKLGTR	CAVIN1	266	Q6NZI2
SRVHKGKSTRKEENT	ASCC2	556	Q9H1I8
GHGQSRETTQERRKK	ASCC2	716	Q9H1I8
IRRHRKSKVTGAEQS	AMER1	176	Q5JTC6
RGKKDGEKTRRVSSH	ANKRD36B	516	Q8N2N9
KESISHKIRQEKGTR	DNHD1	2761	Q96M86
RTVHKRKLKAIVAGS	CDH23	3091	Q9H251
SVDARGRHQKKIRSK	ATP10A	781	O60312
THVSTIRKLVGKRKN	CFAP91	336	Q7Z4T9
RKRSHSSAQENKRCK	CLK1	31	P49759
EAPKKKHRRNRTTFT	RAX2	21	Q96IS3
KKSKSRSRSHERKRS	RBM39	36	Q14498
ARGKKHGEKTRRVSS	ANKRD36C	941	Q5JPF3
KGIGRRKTQHKRTQV	ANKRD31	726	Q8N7Z5
ETGIRKTVKRLRKHQ	ELOA2	46	Q8IYF1
SDGRSRKSKKKRQQH	GPATCH4	371	Q5T3I0
GKITAGKHRRLTRKS	PCLO	1601	Q9Y6V0
SKSSATRSKKRQHRV	PHRF1	361	Q9P1Y6
SRKKAKRKRVSREHG	PHRF1	1001	Q9P1Y6
KTSLAKHRIGTKRHR	KDM4A	386	O75164
THKARTRPKARKQGV	ADAMTSL2	546	Q86TH1
GQRKRRNTIHEFKKS	HGF	31	P14210
RTKLAHFRQRKTKGD	PCNT	16	O95613
RSRSKGRDHENVKEK	PPIG	486	Q13427
HRKRKHERKRSTGGR	PPP1R16B	46	Q96T49
HERKRSTGGRRKKVS	PPP1R16B	51	Q96T49
KRGRSKKAHVLAASV	CTNNA1	51	P35221
QTAESRKKSGRHVTR	C19orf44	511	Q9H6X5
RSHRRIEKKGSDKRT	DGKB	681	Q9Y6T7
IKRRKSNRSADHAKQ	BTBD7	71	Q9P203
RTHEKGRQSTRLKML	F10	366	P00742
KVTKNVSKPRHSRRR	RPL36	16	Q9Y3U8
RRSGKSSIQKVVFHK	RRAGD	71	Q9NQL2
GSLKKKQRRQRTHFT	PITX3	56	O75364
KTSRSLHVRVQKSKA	PRDM2	1606	Q13029
KRKSDNEGRKHRSRS	RSRC2	51	Q7L4I2
RHKRKERKSSRGRSH	RSRC2	111	Q7L4I2
RKKESQGSGTAVRKH	SPHKAP	981	Q2M3C7
TGHNREASKKRKVRT	SVIL	531	O95425
KRRLRSSGKKNSVSH	NKTR	756	P30414
SGERQRKRHKSDSIS	MDM2	176	Q00987
RRKGKREFGKTITHI	SHCBP1L	371	Q9BZQ2
TASSRHGIQKKLKRV	SP110	301	Q9HB58
HRTRRGKVSPTAKTK	COL24A1	6	Q17RW2
GHKKRVRRSSFLNAK	RAPGEF2	951	Q9Y4G8
RTRRAKGKNKHSKRA	USP17L3	511	A6NCW0
KRFEHSAKQRRKITT	USP27X	311	A6NNY8
KFQRKRRHKLKESTT	VSTM5	176	A8MXK1
RTRRSKGKNKHSKRS	USP17L4	511	A6NCW7
PTTRTRGKRNRKSKH	TRO	401	Q12816
IAHKRTRYTTEGRKK	PYROXD1	206	Q8WU10
KTGEVSKRRKAHLRR	SH3PXD2A	236	Q5TCZ1
GTSKKHSAAILRKER	SP2	396	Q02086
QSKGVKTERSHRGVK	ZNF558	136	Q96NG5
RARRSKGKNKHSKRA	USP17L18	511	D6R9N7
RARRSKGKNKHSKRA	USP17L5	511	A8MUK1
RARRSKGKNKHSKRA	USP17L21	511	D6R901
RARRSKGKNKHSKRA	USP17L13	511	C9JLJ4
RARRSKGKNKHSKRA	USP17L19	511	D6RCP7
RHKKHKRNRSESSRS	TTC14	501	Q96N46
KRKHRRLKNSKASTD	PREX2	276	Q70Z35
RTRRAKGKNKHSKRA	USP17L1	511	Q7RTZ2
RARRSKGKNKHSKRA	USP17L12	511	C9JPN9
RARRSKGKNKHSKRA	USP17L24	511	Q0WX57
KHSGRLRVTLDTSKK	TRAV17	76	A0A0B4J275
RTRRSKGKNKHSKRS	USP17L8	511	P0C7I0
RNGESERKKSSHRGK	ZRSR2P1	396	Q15695
QRRNSSKTKATIHKR	TTC16	691	Q8NEE8
KSRLRKHQRTHTGEK	ZNF782	406	Q6ZMW2
RARRSKGKNKHSKRA	USP17L22	511	D6RA61
RARRSKGKNKHSKRA	USP17L15	511	C9J2P7
RARRSKGKNKHSKRA	USP17L17	511	D6RBQ6
ERKSSRHRGKKSHKR	ZRSR2	396	Q15696
RHRGKKSHKRTSKSR	ZRSR2	401	Q15696
GRKKISPDKRQHVSR	TEX36	91	Q5VZQ5
RTRRSKGKNKHSKRA	USP17L2	511	Q6R6M4
RARRSKGKNKHSKRA	USP17L20	511	D6RJB6
RTRRSKGKNKHSKRA	USP17L10	511	C9JJH3
RARRSKGKNKHSKRA	USP17L11	511	C9JVI0
GSNRKTKSRVARKAH	ZNF518B	751	Q9C0D4
VRQRKSHTRTKKGPA	KMT2D	1701	O14686