Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cell adhesion molecule binding	FLNB DSP PKP4 LARP1 LAMB2 ADGRL1 EMILIN1 IGF1 NRXN3 MYPN IGSF9 AFDN CTNND2 ROBO3	5.34e-06	599	110	14	GO:0050839
GeneOntologyMolecularFunction	cell adhesion mediator activity	DSP EMILIN1 MYPN IGSF9 ROBO3	6.27e-05	76	110	5	GO:0098631
GeneOntologyMolecularFunction	protein phosphatase 2A binding	VIM MAPT ANKLE2 EIF4EBP1	8.30e-05	42	110	4	GO:0051721
GeneOntologyMolecularFunction	cell-cell adhesion mediator activity	DSP MYPN IGSF9 ROBO3	3.57e-04	61	110	4	GO:0098632
GeneOntologyMolecularFunction	keratin filament binding	VIM KRT14	4.45e-04	6	110	2	GO:1990254
GeneOntologyMolecularFunction	phosphatase binding	VIM MAPT WNK1 ANKLE2 LGALS3 EIF4EBP1 IRS2	6.52e-04	264	110	7	GO:0019902
GeneOntologyMolecularFunction	enzyme regulator activity	RANBP10 COL7A1 HTRA2 BCAS3 SH2D3C RAPGEF1 ARHGEF17 WNK1 ANKLE2 LGALS3 WDR91 TBC1D10C RIN1 IGF1 PPP1R16B IRS2 TRIB1 RAPGEFL1	7.20e-04	1418	110	18	GO:0030234
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	TCF3 FOXK2 TCF12 CEBPE GLIS3 E2F3 LHX3 KMT2D KLF1 ASCL2	1.06e-03	560	110	10	GO:0001228
GeneOntologyMolecularFunction	protein phosphatase binding	VIM MAPT ANKLE2 LGALS3 EIF4EBP1 IRS2	1.09e-03	210	110	6	GO:0019903
GeneOntologyMolecularFunction	bHLH transcription factor binding	TCF3 TCF12 ASCL2	1.10e-03	37	110	3	GO:0043425
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	TCF3 FOXK2 TCF12 CEBPE GLIS3 E2F3 LHX3 KMT2D KLF1 ASCL2	1.15e-03	566	110	10	GO:0001216
GeneOntologyMolecularFunction	eukaryotic initiation factor 4E binding	LARP1 EIF4EBP1	1.60e-03	11	110	2	GO:0008190
GeneOntologyBiologicalProcess	cell-cell adhesion	ZC3H12A DSG3 DSP PKP4 PCDH11Y RAPGEF1 ADGRL1 CLDN3 WNK1 EMILIN1 LGALS3 CLDN9 IGF1 NRXN3 ASCL2 MYPN PCDH11X IGSF9 AFDN IGSF9B CTNND2 ROBO3	3.94e-08	1077	109	22	GO:0098609
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	DSG3 PCDH11Y ADGRL1 CLDN3 WNK1 CLDN9 MYPN PCDH11X IGSF9 IGSF9B ROBO3	8.44e-07	313	109	11	GO:0098742
GeneOntologyBiologicalProcess	cell junction organization	DSP MAPT PKP4 DVL1 LAMB2 RAPGEF1 ADGRL1 CLDN3 THSD1 CLDN9 NRXN3 IGSF9 AFDN TANC1 IGSF9B CTNND2	5.20e-05	974	109	16	GO:0034330
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	DSG3 PCDH11Y MYPN PCDH11X IGSF9 IGSF9B ROBO3	6.15e-05	187	109	7	GO:0007156
GeneOntologyCellularComponent	cornified envelope	KRT14 DSG3 DSP PKP4 LGALS3	2.65e-05	69	106	5	GO:0001533
GeneOntologyCellularComponent	chromatin	NCAPD3 TCF3 FOXK2 IRX5 TCF12 CEBPE HTRA2 BCAS3 E2F3 LHX3 ZC3H6 DMBX1 PHC2 KLF1 SLF2 ASCL2 ZMIZ2 ZFHX2 IRX2	1.50e-04	1480	106	19	GO:0000785
GeneOntologyCellularComponent	desmosome	DSG3 DSP PKP4	3.79e-04	28	106	3	GO:0030057
Domain	DVL-1	DVL1P1 DVL1	3.44e-05	2	110	2	IPR008340
Domain	Keratin_I	VIM KRT8 KRT14 KRT25	1.29e-04	44	110	4	IPR002957
Domain	Dishevelled_fam	DVL1P1 DVL1	2.05e-04	4	110	2	IPR008339
Domain	Dishevelled	DVL1P1 DVL1	2.05e-04	4	110	2	PF02377
Domain	Dishevelled_protein_dom	DVL1P1 DVL1	2.05e-04	4	110	2	IPR003351
Domain	Protocadherin	PCDH11Y PCDH11X	3.40e-04	5	110	2	PF08374
Domain	Protocadherin	PCDH11Y PCDH11X	3.40e-04	5	110	2	IPR013585
Domain	RASGEF	SH2D3C RAPGEF1 RAPGEFL1	4.68e-04	26	110	3	PS00720
Domain	IRO	IRX5 IRX2	5.08e-04	6	110	2	SM00548
Domain	Iroquois_homeo	IRX5 IRX2	5.08e-04	6	110	2	IPR003893
Domain	RASGEF_CAT	SH2D3C RAPGEF1 RAPGEFL1	6.50e-04	29	110	3	PS50009
Domain	DIX	DVL1P1 DVL1	7.08e-04	7	110	2	PF00778
Domain	Plakophilin/d_Catenin	PKP4 CTNND2	7.08e-04	7	110	2	IPR028435
Domain	DIX	DVL1P1 DVL1	7.08e-04	7	110	2	IPR001158
Domain	DIX	DVL1P1 DVL1	7.08e-04	7	110	2	PS50841
Domain	DAX	DVL1P1 DVL1	7.08e-04	7	110	2	SM00021
Domain	RasGEF	SH2D3C RAPGEF1 RAPGEFL1	7.19e-04	30	110	3	PF00617
Domain	-	SH2D3C RAPGEF1 RAPGEFL1	7.19e-04	30	110	3	1.10.840.10
Domain	Ras_GEF_dom	SH2D3C RAPGEF1 RAPGEFL1	7.19e-04	30	110	3	IPR023578
Domain	RASGEF_cat_dom	SH2D3C RAPGEF1 RAPGEFL1	7.19e-04	30	110	3	IPR001895
Domain	RasGEF	SH2D3C RAPGEF1 RAPGEFL1	7.19e-04	30	110	3	SM00147
Domain	Filament	VIM KRT8 KRT14 KRT25	8.17e-04	71	110	4	SM01391
Domain	IF	VIM KRT8 KRT14 KRT25	8.61e-04	72	110	4	PS00226
Domain	Filament	VIM KRT8 KRT14 KRT25	9.07e-04	73	110	4	PF00038
Domain	IF	VIM KRT8 KRT14 KRT25	1.05e-03	76	110	4	IPR001664
Pathway	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE	KRT8 KRT14 DSG3 DSP PKP4 KRT25	9.68e-06	87	80	6	MM15351
Pathway	WP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY	VIM DSP LAMB2 EIF4EBP1 IRS2	3.54e-05	66	80	5	MM15925
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS	VIM DSG3 DSP MAPT	5.51e-05	37	80	4	MM14488
Pathway	REACTOME_APOPTOTIC_CLEAVAGE_OF_CELLULAR_PROTEINS	VIM DSG3 DSP MAPT	6.13e-05	38	80	4	M495
Pathway	REACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE	KRT8 KRT14 DSG3 DSP PKP4 KRT25	9.02e-05	129	80	6	M27649
Pathway	REACTOME_APOPTOTIC_EXECUTION_PHASE	VIM DSG3 DSP MAPT	1.68e-04	49	80	4	MM15448
Pathway	REACTOME_APOPTOTIC_EXECUTION_PHASE	VIM DSG3 DSP MAPT	2.12e-04	52	80	4	M2341
Pathway	REACTOME_KERATINIZATION	KRT8 KRT14 DSG3 DSP PKP4 KRT25	2.30e-04	153	80	6	MM15343
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	KRT8 TCF3 KRT14 TCF12 DSG3 DSP PKP4 MYRIP IRS2 KRT25	5.27e-04	502	80	10	MM14537
Pathway	REACTOME_CELL_JUNCTION_ORGANIZATION	ZC3H12A KRT14 CLDN3 CLDN9 AFDN	5.29e-04	117	80	5	M19248
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	RANBP10 FOXK2 UBE4B BCAS3 DVL1 LAMB2 RAPGEF1 ADGRL1 SLC10A3 CLDN3 EDC4 WNK1 ATP13A2 PHC2 KMT2D GAREM2 ZMIZ2 KANK3 IRS2 TANC1 TRIB1 BAHCC1	7.05e-12	1105	112	22	35748872
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	VIM KRT8 ZNF326 DSP MAPT BCAS3 LARP1 EDC4 ARHGEF17 WNK1 FSIP2 SLF2 AFDN IRS2 TANC1 PRRC1	1.80e-08	861	112	16	36931259
Pubmed	Interaction of plakophilins with desmoplakin and intermediate filament proteins: an in vitro analysis.	VIM KRT8 KRT14 DSP	2.11e-08	10	112	4	10852826
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	VIM FLNB KRT8 FOXK2 LARP1 WNK1 ANKLE2 RIN1 MYPN AFDN IRS2 RAVER1	8.78e-08	503	112	12	16964243
Pubmed	The mesenchymal property of mouse mammary anlagen repopulating cell population is associated with its stemness.	VIM KRT8 KRT14	1.30e-07	4	112	3	33132190
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	VIM FLNB KRT14 SNPH DSP MAPT BCAS3 PKP4 KIAA1549 LARP1 ADGRL1 EDC4 ARHGEF17 RIN1 SEC24C AFDN TANC1 CTNND2 MTUS2	1.54e-07	1431	112	19	37142655
Pubmed	Desmocollin 3 is required for pre-implantation development of the mouse embryo.	KRT8 KRT14 DSG3 DSP	1.80e-07	16	112	4	16418220
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FLNB TCF3 FOXK2 UBE4B MAPT BCAS3 PCDH11Y MYRIP LARP1 ADGRL1 E2F3 SNX29 CLCC1 IGF1 ZFHX2 IGSF9 TANC1 IGSF9B RAVER1	2.82e-07	1489	112	19	28611215
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	KRT8 KRT14 SNPH FXR2 LAMB2 EMILIN1 GRSF1 SNX29 IQCA1L SLTM SEC61A1	6.39e-07	496	112	11	31343991
Pubmed	Characterization of human epiplakin: RNAi-mediated epiplakin depletion leads to the disruption of keratin and vimentin IF networks.	VIM KRT8 KRT14	6.46e-07	6	112	3	15671067
Pubmed	Unique role for the periplakin tail in intermediate filament association: specific binding to keratin 8 and vimentin.	VIM KRT8 DSP	6.46e-07	6	112	3	12366696
Pubmed	The HAND1 basic helix-loop-helix transcription factor regulates trophoblast differentiation via multiple mechanisms.	TCF3 TCF12 ASCL2	6.46e-07	6	112	3	10611232
Pubmed	Keratins regulate protein biosynthesis through localization of GLUT1 and -3 upstream of AMP kinase and Raptor.	VIM KRT8 DSP EIF4EBP1	8.61e-07	23	112	4	19841136
Pubmed	Ubiquitin-assisted phase separation of dishevelled-2 promotes Wnt signalling.	VIM RANBP10 DVL1P1 FOXK2 DVL1 IRS2 TANC1	9.63e-07	161	112	7	36398662
Pubmed	ID1 and CEBPA coordinate epidermal progenitor cell differentiation.	TCF3 KRT14 TCF12	1.13e-06	7	112	3	36330928
Pubmed	A census of human transcription factors: function, expression and evolution.	TCF3 FOXK2 IRX5 TCF12 CEBPE KIAA1549 E2F3 LHX3 DMBX1 KMT2D KLF1 ASCL2 ZFHX2 IRX2	1.39e-06	908	112	14	19274049
Pubmed	Interaction of plectin with keratins 5 and 14: dependence on several plectin domains and keratin quaternary structure.	VIM KRT8 KRT14	3.84e-06	10	112	3	24940650
Pubmed	Do polymorphisms in the familial Parkinsonism genes contribute to risk for sporadic Parkinson's disease?	HTRA2 MAPT ATP13A2	5.26e-06	11	112	3	19224617
Pubmed	Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people.	GLIS3 ADRA2A IGF1	7.00e-06	12	112	3	20419449
Pubmed	BCAS3 exhibits oncogenic properties by promoting CRL4A-mediated ubiquitination of p53 in breast cancer.	VIM DSP BCAS3	7.00e-06	12	112	3	34240781
Pubmed	Lessons from thymic epithelial heterogeneity: FoxN1 and tissue-restricted gene expression by extrathymic, endodermally derived epithelium.	KRT8 KRT14 CLDN3	7.00e-06	12	112	3	19786540
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	VIM FLNB KRT8 DSP LAMB2 EDC4 SEC61A1	7.38e-06	219	112	7	31353912
Pubmed	Residual embryonic cells as precursors of a Barrett's-like metaplasia.	KRT8 KRT14 CLDN3	9.08e-06	13	112	3	21703447
Pubmed	Downregulation of E Protein Activity Augments an ILC2 Differentiation Program in the Thymus.	TCF3 TCF12	1.03e-05	2	112	2	28258196
Pubmed	Acquisition of a functional T cell receptor during T lymphocyte development is enforced by HEB and E2A transcription factors.	TCF3 TCF12	1.03e-05	2	112	2	18093538
Pubmed	Functions of E2A-HEB heterodimers in T-cell development revealed by a dominant negative mutation of HEB.	TCF3 TCF12	1.03e-05	2	112	2	10958665
Pubmed	An essential role for the transcription factor HEB in thymocyte survival, Tcra rearrangement and the development of natural killer T cells.	TCF3 TCF12	1.03e-05	2	112	2	20154672
Pubmed	Conservation of PCDHX in mammals; expression of human X/Y genes predominantly in brain.	PCDH11Y PCDH11X	1.03e-05	2	112	2	11003707
Pubmed	E2A promotes the survival of precursor and mature B lymphocytes.	TCF3 TCF12	1.03e-05	2	112	2	16888011
Pubmed	Pcdh11x Negatively Regulates Dendritic Branching.	PCDH11Y PCDH11X	1.03e-05	2	112	2	25687328
Pubmed	IRS-2 branch of IGF-1 receptor signaling is essential for appropriate timing of myelination.	IGF1 IRS2	1.03e-05	2	112	2	18717815
Pubmed	Stress Conditions Increase Vimentin Cleavage by Omi/HtrA2 Protease in Human Primary Neurons and Differentiated Neuroblastoma Cells.	VIM HTRA2	1.03e-05	2	112	2	25288153
Pubmed	Vimentin regulates differentiation switch via modulation of keratin 14 levels and their expression together correlates with poor prognosis in oral cancer patients.	VIM KRT14	1.03e-05	2	112	2	28225793
Pubmed	E2A and HEB are required to block thymocyte proliferation prior to pre-TCR expression.	TCF3 TCF12	1.03e-05	2	112	2	17442955
Pubmed	Epidermolysis Bullosa: Two rare case reports of COL7A1 and EBS-GEN SEV KRT14 variants with review of literature.	COL7A1 KRT14	1.03e-05	2	112	2	38580989
Pubmed	Cadherin expression delineates the divisions of the postnatal and adult mouse amygdala.	PCDH11Y PCDH11X	1.03e-05	2	112	2	22592879
Pubmed	Protocadherin X ( PCDHX) and Y ( PCDHY) genes; multiple mRNA isoforms encoding variant signal peptides and cytoplasmic domains.	PCDH11Y PCDH11X	1.03e-05	2	112	2	14727141
Pubmed	Correlation between circulating innate lymphoid cell precursors and thymic function.	TCF3 TCF12	1.03e-05	2	112	2	35118353
Pubmed	Lack of association between protocadherin 11-X/Y (PCDH11X and PCDH11Y) polymorphisms and late onset Alzheimer's disease.	PCDH11Y PCDH11X	1.03e-05	2	112	2	21276771
Pubmed	Mapping putative enhancers in mouse oocytes and early embryos reveals TCF3/12 as key folliculogenesis regulators.	TCF3 TCF12	1.03e-05	2	112	2	38839978
Pubmed	Human homologue sequences to the Drosophila dishevelled segment-polarity gene are deleted in the DiGeorge syndrome.	DVL1P1 DVL1	1.03e-05	2	112	2	8644734
Pubmed	Identification and localization of a neurally expressed member of the plakoglobin/armadillo multigene family.	PKP4 CTNND2	1.03e-05	2	112	2	9342840
Pubmed	Accelerated evolution of Protocadherin11X/Y: a candidate gene-pair for cerebral asymmetry and language.	PCDH11Y PCDH11X	1.03e-05	2	112	2	16874762
Pubmed	PCDH11 is X/Y homologous in Homo sapiens but not in Gorilla gorilla and Pan troglodytes.	PCDH11Y PCDH11X	1.03e-05	2	112	2	16825765
Pubmed	The protocadherin 11X/Y (PCDH11X/Y) gene pair as determinant of cerebral asymmetry in modern Homo sapiens.	PCDH11Y PCDH11X	1.03e-05	2	112	2	23600975
Pubmed	A comparative analysis of the pig, mouse, and human PCDHX genes.	PCDH11Y PCDH11X	1.03e-05	2	112	2	15112107
Pubmed	Co-expression of galectin-3 and vimentin in triple negative breast cancer cells promotes tumor progression, metastasis and survival.	VIM LGALS3	1.03e-05	2	112	2	37574746
Pubmed	Protocadherin 11X/Y a human-specific gene pair: an immunohistochemical survey of fetal and adult brains.	PCDH11Y PCDH11X	1.03e-05	2	112	2	22744706
Pubmed	Rudhira/BCAS3 is a cytoskeletal protein that controls Cdc42 activation and directional cell migration during angiogenesis.	VIM BCAS3	1.03e-05	2	112	2	22300583
Pubmed	Tau is hyperphosphorylated in the insulin-like growth factor-I null brain.	MAPT IGF1	1.03e-05	2	112	2	16123158
Pubmed	Galectin-3 aggravates microglial activation and tau transmission in tauopathy.	MAPT LGALS3	1.03e-05	2	112	2	37988169
Pubmed	E proteins orchestrate dynamic transcriptional cascades implicated in the suppression of the differentiation of group 2 innate lymphoid cells.	TCF3 TCF12	1.03e-05	2	112	2	32817168
Pubmed	Quantitative analysis of alternative transcripts of human PCDH11X/Y genes.	PCDH11Y PCDH11X	1.03e-05	2	112	2	19859901
Pubmed	Increased tau phosphorylation and impaired brain insulin/IGF signaling in mice fed a high fat/high cholesterol diet.	MAPT IGF1	1.03e-05	2	112	2	23703152
Pubmed	An analysis of T cell intrinsic roles of E2A by conditional gene disruption in the thymus.	TCF3 TCF12	1.03e-05	2	112	2	11937548
Pubmed	Epithelial cell migration requires the interaction between the vimentin and keratin intermediate filaments.	VIM KRT14	1.03e-05	2	112	2	27072292
Pubmed	Perp is a p63-regulated gene essential for epithelial integrity.	KRT14 DSG3 DSP	1.15e-05	14	112	3	15797384
Pubmed	NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development.	KRT8 KRT14 CLDN3	1.44e-05	15	112	3	32467240
Pubmed	Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism.	VIM KRT8 KRT14	1.77e-05	16	112	3	21624358
Pubmed	RPGRIP1L is required for stabilizing epidermal keratinocyte adhesion through regulating desmoglein endocytosis.	KRT14 DSG3 DSP	1.77e-05	16	112	3	30689641
Pubmed	The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.	FLNB KRT8 DSP DVL1 LARP1 MYPN TANC1	2.02e-05	256	112	7	33397691
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	KRT8 FOXK2 IRX5 LHX3 DMBX1 ZFHX2 IRX2	2.41e-05	263	112	7	20932939
Pubmed	A human MAP kinase interactome.	KRT8 KRT14 DSP LAMB2 RAPGEF1 ADGRL1 WNK1 ATF7IP NAV3	2.91e-05	486	112	9	20936779
Pubmed	Androgen action in cell fate and communication during prostate development at single-cell resolution.	VIM KRT8 KRT14	3.03e-05	19	112	3	33318148
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	VIM TCF3 ZC3H12A FOXK2 TCF12 BCAS3 DVL1 EDC4 WNK1 WDR91 SEC24C MYPN IRS2	3.07e-05	1038	112	13	26673895
Pubmed	E-protein-regulated expression of CXCR4 adheres preselection thymocytes to the thymic cortex.	TCF3 TCF12	3.08e-05	3	112	2	31201207
Pubmed	Context-dependent regulation of hematopoietic lineage choice by HEBAlt.	TCF3 TCF12	3.08e-05	3	112	2	20826759
Pubmed	Climbing fiber input shapes reciprocity of Purkinje cell firing.	MAPT ROBO3	3.08e-05	3	112	2	23643935
Pubmed	Expression of cytokeratin 8, vimentin, syndecan-1 and Ki-67 during human tooth development.	VIM KRT8	3.08e-05	3	112	2	25120060
Pubmed	Monoallelic Heb/Tcf12 Deletion Reduces the Requirement for NOTCH1 Hyperactivation in T-Cell Acute Lymphoblastic Leukemia.	TCF3 TCF12	3.08e-05	3	112	2	35401501
Pubmed	Association of Cytokeratin 5 and Claudin 3 expression with BRCA1 and BRCA2 germline mutations in women with early breast cancer.	KRT14 CLDN3	3.08e-05	3	112	2	31307407
Pubmed	Overexpression of the mouse dishevelled-1 protein inhibits GSK-3beta-mediated phosphorylation of tau in transfected mammalian cells.	MAPT DVL1	3.08e-05	3	112	2	9271238
Pubmed	E2-2 regulates the expansion of pro-B cells and follicular versus marginal zone decisions.	TCF3 TCF12	3.08e-05	3	112	2	17082585
Pubmed	Decreased expression of claudin-3 is associated with a poor prognosis and EMT in completely resected squamous cell lung carcinoma.	VIM CLDN3	3.08e-05	3	112	2	25820701
Pubmed	Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors.	TCF3 TCF12	3.08e-05	3	112	2	30898894
Pubmed	PAPIN. A novel multiple PSD-95/Dlg-A/ZO-1 protein interacting with neural plakophilin-related armadillo repeat protein/delta-catenin and p0071.	PKP4 CTNND2	3.08e-05	3	112	2	10896674
Pubmed	The transition to endoreduplication in trophoblast giant cells is regulated by the mSNA zinc finger transcription factor.	TCF3 ASCL2	3.08e-05	3	112	2	9676199
Pubmed	EVA regulates thymic stromal organisation and early thymocyte development.	KRT8 KRT14	3.08e-05	3	112	2	17362876
Pubmed	A role for E2-2 at the DN3 stage of early thymopoiesis.	TCF3 TCF12	3.08e-05	3	112	2	18384878
Pubmed	Cadherin expression in the somatosensory cortex: evidence for a combinatorial molecular code at the single-cell level.	PCDH11Y PCDH11X	3.08e-05	3	112	2	21129452
Pubmed	Nuclear targeting of the transcription factor PTF1 is mediated by a protein subunit that does not bind to the PTF1 cognate sequence.	TCF3 TCF12	3.08e-05	3	112	2	1720355
Pubmed	Next-generation sequencing through multigene panel testing for the diagnosis of hereditary epidermolysis bullosa in Chinese population.	COL7A1 KRT14	3.08e-05	3	112	2	32484238
Pubmed	The coordinate cellular response to insulin-like growth factor-I (IGF-I) and insulin-like growth factor-binding protein-2 (IGFBP-2) is regulated through vimentin binding to receptor tyrosine phosphatase β (RPTPβ).	VIM IGF1	3.08e-05	3	112	2	25787077
Pubmed	Cubilin, a binding partner for galectin-3 in the murine utero-placental complex.	CUBN LGALS3	3.08e-05	3	112	2	11856751
Pubmed	Identification of a WD40 repeat-containing isoform of PHIP as a novel regulator of beta-cell growth and survival.	IGF1 IRS2	3.08e-05	3	112	2	17636024
Pubmed	The helix-loop-helix gene E2A is required for B cell formation.	TCF3 TCF12	3.08e-05	3	112	2	8001124
Pubmed	Different roles of E proteins in t(8;21) leukemia: E2-2 compromises the function of AETFC and negatively regulates leukemogenesis.	TCF3 TCF12	3.08e-05	3	112	2	30593567
Pubmed	Replication study of the association of SNPs in the LHX3-QSOX2 and IGF1 loci with adult height in the Japanese population; wide-ranging comparison of each SNP genotype distribution.	LHX3 IGF1	3.08e-05	3	112	2	22503243
Pubmed	Where and what is the right shift factor or cerebral dominance gene? A critique of Francks et al. (2007).	PCDH11Y PCDH11X	3.08e-05	3	112	2	19125366
Pubmed	IRS2 integrates insulin/IGF1 signalling with metabolism, neurodegeneration and longevity.	IGF1 IRS2	3.08e-05	3	112	2	25200290
Pubmed	Activated 4E-BP1 represses tumourigenesis and IGF-I-mediated activation of the eIF4F complex in mesothelioma.	IGF1 EIF4EBP1	3.08e-05	3	112	2	19603014
Pubmed	Insulin receptor substrate 2 is required for testicular development.	IGF1 IRS2	3.08e-05	3	112	2	23741292
Pubmed	Non-clustered protocadherin.	PCDH11Y PCDH11X	3.08e-05	3	112	2	21173574
Pubmed	Murine helix-loop-helix transcriptional activator proteins binding to the E-box motif of the Akv murine leukemia virus enhancer identified by cDNA cloning.	TCF3 TCF12	3.08e-05	3	112	2	1321336
Pubmed	TAL1/SCL induces leukemia by inhibiting the transcriptional activity of E47/HEB.	TCF3 TCF12	3.08e-05	3	112	2	15193261
Pubmed	Role of the basic helix-loop-helix transcription factor p48 in the differentiation phenotype of exocrine pancreas cancer cells.	TCF3 TCF12	3.08e-05	3	112	2	10768861
Pubmed	B-lymphocyte development is regulated by the combined dosage of three basic helix-loop-helix genes, E2A, E2-2, and HEB.	TCF3 TCF12	3.08e-05	3	112	2	8649400
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	VIM KRT8 KRT14 DSP PKP4 KIAA1549 ANKLE2 CLCC1 KMT2D SLTM TANC1 SEC61A1 RAVER1	3.42e-05	1049	112	13	27880917
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	VIM FLNB MAPT DVL1 LARP1 EDC4 SEC24C GNL1 RAVER1	3.51e-05	498	112	9	36634849
Pubmed	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	GLIS3 ADRA2A IGF1	3.56e-05	20	112	3	20081858
Interaction	TOP3B interactions	RANBP10 FOXK2 UBE4B FXR2 BCAS3 DVL1 LAMB2 RAPGEF1 ADGRL1 SLC10A3 CLDN3 EDC4 WNK1 ATP13A2 GRSF1 PHC2 KMT2D GAREM2 ZMIZ2 KANK3 IRS2 TANC1 TRIB1 BAHCC1	1.00e-06	1470	110	24	int:TOP3B
Interaction	OR7A5 interactions	UBL7 UBE4B KIAA1549	5.45e-06	7	110	3	int:OR7A5
Interaction	MAPK3 interactions	VIM KRT8 TCF3 NPTX2 HTRA2 UBE4B MAPT GRSF1 LGALS3 ATF7IP IRX2	1.94e-05	421	110	11	int:MAPK3
Interaction	KRT6A interactions	VIM KRT8 KRT14 DSG3 DSP KRT25 MTUS2	2.80e-05	160	110	7	int:KRT6A
GeneFamily	Fibronectin type III domain containing	COL7A1 ATF7IP IGSF9 IGSF9B ROBO3	5.68e-04	160	76	5	555
GeneFamily	Non-clustered protocadherins	PCDH11Y PCDH11X	1.12e-03	12	76	2	21
GeneFamily	Parkinson disease associated genes	HTRA2 ATP13A2	2.01e-03	16	76	2	672
Coexpression	LAKE_ADULT_KIDNEY_C5_PROXIMAL_TUBULE_EPITHELIAL_CELLS_STRESS_INFLAM	UBE4B FXR2 MAPT MYRIP KIAA1549 LARP1 ZFC3H1 CUBN ZC3H6 SNX29 PPP1R16B	1.65e-06	417	111	11	M39224
Coexpression	GSE19888_ADENOSINE_A3R_ACT_VS_TCELL_MEMBRANES_ACT_AND_A3R_INH_PRETREAT_IN_MAST_CELL_DN	RANBP10 COL7A1 DSP ZFC3H1 RIN1 KMT2D TANC1 RAPGEFL1	2.17e-06	199	111	8	M7319
Coexpression	VALK_AML_CLUSTER_10	FLNB ADGRL1 ARHGEF17 PPP1R16B	1.13e-05	33	111	4	M18784
Coexpression	GSE5503_MLN_DC_VS_PLN_DC_ACTIVATED_ALLOGENIC_TCELL_DN	UBE4B WNK1 ANKLE2 ATF7IP CTNND2 SEC61A1 RAPGEFL1	2.36e-05	200	111	7	M291
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HOPC	KRT14 ATP13A2 IGF1 GAREM2 PCDH11X IGSF9B MAML2 CTNND2 ROBO3	2.64e-05	366	111	9	M39052
Coexpression	GSE6092_CTRL_VS_BORRELIA_BIRGDOFERI_INF_ENDOTHELIAL_CELL_DN	CLDN3 LHX3 ZFC3H1 CUBN WNK1 IRS2	4.23e-05	149	111	6	M6708
Coexpression	PASINI_SUZ12_TARGETS_DN	VIM KRT8 TCF12 DSP WNK1 PHC2 IRS2 TRIB1	6.15e-05	316	111	8	M2293
Coexpression	PASINI_SUZ12_TARGETS_DN	VIM KRT8 TCF12 DSP WNK1 PHC2 IRS2 TRIB1	7.17e-05	323	111	8	MM1066
Coexpression	KRIEG_HYPOXIA_NOT_VIA_KDM3A	VIM TCF3 RAPGEF1 SLC10A3 ANKLE2 GRSF1 LGALS3 PHC2 ZMIZ2 EIF4EBP1 IRS2 RAVER1	7.78e-05	746	111	12	M2469
Coexpression	MURAKAMI_UV_RESPONSE_24HR	KRT14 DSP DVL1	8.00e-05	20	111	3	M17175
CoexpressionAtlas	FacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#3	KRT8 KRT14 DSP CLDN3 DMBX1 CLDN9 PCDH11X NAV3 IGSF9	1.68e-05	283	110	9	Facebase_RNAseq_e9.5_Olfactory Placode_1000_K3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_top-relative-expression-ranked_200	KRT8 KRT14 IRX5 DSP CLDN3 CTNND2 IRX2	2.75e-05	168	110	7	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_200
CoexpressionAtlas	FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#1	KRT8 KRT14 DSP CLDN3 DMBX1 CLDN9 PCDH11X NAV3	6.17e-05	259	110	8	Facebase_RNAseq_e10.5_Olfactory Pit_1000_K1
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL7A1 KRT8 KRT14 DSG3 DSP CLDN3 LGALS3 IRX2	1.96e-08	181	112	8	a5e770b5b5d57cbac18560828e89f7c96b687743
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL7A1 KRT8 KRT14 DSG3 DSP CLDN3 LGALS3 IRX2	1.96e-08	181	112	8	504b1af1951a7a20ef5db69d84c20630ec64095b
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL7A1 KRT8 KRT14 DSG3 DSP CLDN3 LGALS3 IRX2	1.96e-08	181	112	8	a55ec36d2393f7a376feb42b22aee75dfdf4c383
ToppCell	facs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL7A1 KRT8 IRX5 DSP CLDN3 ERN2 IRX2 BAIAP2L2	2.52e-08	187	112	8	fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT8 IRX5 DSP CLDN3 ERN2 RNF39 IRX2 BAIAP2L2	2.63e-08	188	112	8	8ffb5394f7b00ea483a5fe4df894d22fda935e5c
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT8 IRX5 DSP CLDN3 ERN2 RNF39 IRX2 BAIAP2L2	2.63e-08	188	112	8	137ed9958044fab7a13648affb469585d1c48cf6
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 DSP CLDN3 CLDN9 CTNND2 IRX2 TRIB1	3.93e-08	198	112	8	c477405b093f4e5374e57bcacf1fb204a0f7eb3b
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KRT8 IRX5 CLDN3 CLDN9 CTNND2 IRX2 TRIB1	4.00e-07	182	112	7	204530444e35d4977a7239ac176f477e9e5c29ab
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 KRT14 DSP E2F3 CLDN3 RNF39 RAPGEFL1	4.00e-07	182	112	7	9174fb0b7ed8f721a5c513e41fd80476a9f34332
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLNB SH2D3C IGF1 NRXN3 KANK3 PPP1R16B ROBO3	4.15e-07	183	112	7	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	droplet-Skin\|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT14 IRX5 DSG3 DSP ASCL2 IRX2 RAPGEFL1	4.47e-07	185	112	7	657fd191ed160f8620d57b33820ec7222806f289
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT8 IRX5 DSP CLDN3 ERN2 IRX2 BAIAP2L2	4.63e-07	186	112	7	37b93ebd64ebbd08193a746e5bc9b350c2570733
ToppCell	facs-Heart-LA-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL7A1 KRT8 KRT14 SNPH CLDN3 ASCL2 DACT3	4.63e-07	186	112	7	246503fd4e6ae24041c606b069eb5fb313e60f73
ToppCell	facs-Heart-LA-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL7A1 KRT8 KRT14 SNPH CLDN3 ASCL2 DACT3	4.63e-07	186	112	7	ef93ac469eb4f63db036f14b442c1503b8c6de38
ToppCell	E12.5-Epithelial-alveolar_epithelial_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KRT8 IRX5 CLDN3 CLDN9 CTNND2 IRX2 TRIB1	4.98e-07	188	112	7	c19c89756f2f999e0814f08a89818ef156f6fc69
ToppCell	facs-Heart-RA-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH2D3C RAPGEF1 THSD1 KANK3 NAV3 PPP1R16B AFDN	5.16e-07	189	112	7	1be5067c1e45af7d09c1fd6955952cb9e031a3a0
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SH2D3C RAPGEF1 THSD1 KANK3 NAV3 PPP1R16B AFDN	5.16e-07	189	112	7	30dc1725d43a60017fb12d706f1f85a33de4947e
ToppCell	IPF-Epithelial-Basal\|IPF / Disease state, Lineage and Cell class	COL7A1 KRT8 KRT14 DSG3 DSP GLIS3 TANC1	5.34e-07	190	112	7	ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCell	facs-Skin\|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT14 DSG3 DSP THSD1 LGALS3 AFDN RAPGEFL1	5.54e-07	191	112	7	ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-GHRL+_NE_precursor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 DSP CLDN3 CLDN9 ASCL2 IRX2	5.54e-07	191	112	7	f0a81f621e63e87ff62224b33cf0c71dfac1d6e2
ToppCell	IPF-Epithelial-Basal\|World / Disease state, Lineage and Cell class	COL7A1 KRT8 KRT14 DSG3 DSP GLIS3 TANC1	5.73e-07	192	112	7	9b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 DSP CLDN3 CLDN9 CTNND2 IRX2	5.73e-07	192	112	7	b73f24d1c55dfef1eb01c26da117dbf637ea080a
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 DSP CLDN3 CLDN9 CTNND2 IRX2	5.94e-07	193	112	7	b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNB PKP4 SH2D3C MYRIP THSD1 PPP1R16B CTNND2	5.94e-07	193	112	7	e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 DSP CLDN3 CLDN9 CTNND2 IRX2	5.94e-07	193	112	7	b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCell	18-Airway-Epithelial-Basal_cell\|Airway / Age, Tissue, Lineage and Cell class	COL7A1 KRT8 DSP ASCL2 IGSF9 RNF39 TRIB1	5.94e-07	193	112	7	5067b0db24f96e26cf3f9437736415f694e7a614
ToppCell	PCW_13-14-Epithelial-Epithelial_airway\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 DSP CLDN3 CLDN9 CTNND2 IRX2	6.15e-07	194	112	7	7b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KRT8 DSP CLDN3 CLDN9 ADRA2A CTNND2 IRX2	6.36e-07	195	112	7	d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCell	facs-Heart-RA-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB SH2D3C RAPGEF1 THSD1 KANK3 PPP1R16B AFDN	6.36e-07	195	112	7	30c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor-epi-airway_progenitor_early\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KRT8 DSP CLDN3 CLDN9 NRXN3 CTNND2 IRX2	6.81e-07	197	112	7	4ae08ccb6f1da626c4f0fb0140a2811cb6e31ba1
ToppCell	11.5-Distal-Epithelial\|Distal / Age, Tissue, Lineage and Cell class	KRT8 IRX5 DSP CLDN3 CLDN9 CTNND2 IRX2	6.81e-07	197	112	7	ae9505ae7e6c5e8c280f9bfb1ba79ab5bd8895e3
ToppCell	11.5-Airway-Epithelial\|Airway / Age, Tissue, Lineage and Cell class	KRT8 IRX5 DSP CLDN3 CLDN9 CTNND2 IRX2	6.81e-07	197	112	7	e671af1b69566d97afe97f1a959a07b6f4c05620
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_late\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 DSP CLDN3 CLDN9 IRX2 TRIB1	7.05e-07	198	112	7	1851b7f4198b42c21c934e2fbda39dbd65e2625c
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FLNB SH2D6 KRT8 DSP CLDN3 LGALS3 ADRA2A	7.05e-07	198	112	7	a631be84e29c277216d89ec6265bd43e87c1dc86
ToppCell	PCW_10-12-Epithelial-Epithelial_airway\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 DSP CLDN3 CLDN9 CTNND2 IRX2	7.05e-07	198	112	7	9a12e5e47236433e512c668005fe3f8be6fde95c
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 ZC3H12A KRT14 DSG3 DSP RNF39 TRIB1	7.05e-07	198	112	7	fc00cb25cdc6c31b7f9d397bc9f9a8f4e9708003
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL7A1 ZC3H12A KRT14 DSG3 DSP IGSF9 RAPGEFL1	7.05e-07	198	112	7	22935a8afac54021f68b5f7a5accf51523e2f336
ToppCell	cellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL7A1 KRT8 KRT14 DSG3 DSP RNF39 RAPGEFL1	7.29e-07	199	112	7	974f71b56f66243c78f2f297a1540e0e186df530
ToppCell	wk_08-11-Epithelial-Airway_epithelial_progenitor\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 DSP CLDN3 CLDN9 CTNND2 IRX2	7.29e-07	199	112	7	af664e0d41a889a75dbf6cf0d50acd26f5ab3a3a
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL7A1 KRT8 KRT14 DSG3 DSP RNF39 RAPGEFL1	7.54e-07	200	112	7	afac850d5a40de0d6f02857cf81a19443d90b1eb
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL7A1 KRT8 KRT14 DSP RNF39 IRX2 TRIB1	7.54e-07	200	112	7	41705bbba40eb5ddca0b223191aac1bce00163b8
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Basal_3\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	COL7A1 KRT8 KRT14 DSP RNF39 IRX2 TRIB1	7.54e-07	200	112	7	53e04399d0308b40ae99fbfaa4ff62bf061822d8
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL7A1 KRT8 KRT14 DSP RNF39 IRX2 TRIB1	7.54e-07	200	112	7	cc8df398532c9324fd3e171000b1ea5c208cd691
ToppCell	E16.5-samps-Epithelial-Alveolar_epithelial_precursor-Uncommitted_AE_cell\|E16.5-samps / Age Group, Lineage, Cell class and subclass	KRT8 IRX5 DSP CLDN3 CTNND2 IRX2	4.58e-06	170	112	6	5a64e05c263df915085988d881808221e2c0f2e2
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 IRX5 CUBN ASCL2 IGSF9 RNF39	4.73e-06	171	112	6	6f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 IRX5 CUBN ASCL2 IGSF9 RNF39	4.73e-06	171	112	6	ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCell	facs-Trachea-nan-18m-Epithelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 KRT14 IRX5 DSP CLDN3 RAPGEFL1	5.40e-06	175	112	6	3883675a726dd0c6c3a7113d59be2a093ea2dc6f
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT8 DSP CLDN3 LGALS3 CLDN9 BAIAP2L2	5.58e-06	176	112	6	e7502a345b2da83a9a60f50cf78f1aef385c99df
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SH2D3C THSD1 IGF1 KANK3 NAV3 PPP1R16B	5.77e-06	177	112	6	c274fbdc141855ff4581d437d4997c64cc193278
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SH2D3C THSD1 IGF1 KANK3 NAV3 PPP1R16B	5.77e-06	177	112	6	f5e6df5cafd003bbfbb3b634ee58d0b1e2be5cc7
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SH2D3C THSD1 IGF1 KANK3 NAV3 PPP1R16B	5.77e-06	177	112	6	c8a51e480b978dc0ded85583261f2c892e085be8
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SH2D6 KRT8 DSP CLDN3 LGALS3 ADRA2A	6.35e-06	180	112	6	8ba9bba0c9fecf184a4332ba4585fb2439f68cd3
ToppCell	droplet-Heart-nan-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATF7IP KANK3 NAV3 PPP1R16B AFDN TANC1	6.56e-06	181	112	6	92d44892bb15771f0ab5fe61879b204b0acbd9b3
ToppCell	18-Airway-Epithelial-Submucosal_gland_basal\|Airway / Age, Tissue, Lineage and Cell class	COL7A1 KRT8 KRT14 ASCL2 RNF39 TRIB1	6.56e-06	181	112	6	33938e6521712058312879f84f4ae381c2bfc379
ToppCell	droplet-Lung-nan-3m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 IRX5 DSP CLDN3 CTNND2 IRX2	6.77e-06	182	112	6	cfba75c1ffc39ac76db9e8e27394731942882b30
ToppCell	droplet-Lung-nan-3m-Epithelial-Alveolar_Epithelial_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 IRX5 DSP CLDN3 CTNND2 IRX2	6.77e-06	182	112	6	d836bfdc298ecd3558a973e393a329eb8bd59d79
ToppCell	droplet-Heart-nan-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATF7IP KANK3 NAV3 PPP1R16B AFDN TANC1	6.77e-06	182	112	6	81279877b920b5a1bc991a07d3031d6458700fe3
ToppCell	droplet-Lung-nan-3m-Epithelial-type_II_pneumocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 IRX5 DSP CLDN3 CTNND2 IRX2	6.77e-06	182	112	6	7e7c7a26460d3003cdf0c0ffb96208a566aa09a7
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epi_progenitor\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KRT8 IRX5 CLDN3 CLDN9 CTNND2 IRX2	6.98e-06	183	112	6	031b4ffd95114dc10d2932c67d2cfef139b3fd2e
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT8 KRT14 IRX5 DSP CLDN3 RAPGEFL1	7.20e-06	184	112	6	45ff845ceed5960a997545c1009012b65e377d50
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-Proximal_secretory_progenitors\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 CLDN3 CLDN9 ADRA2A TRIB1	7.20e-06	184	112	6	fcb5dd4fb3fa79f3b6029fad32a474cacde35a3b
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-basal_proximal\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	COL7A1 KRT8 KRT14 DSP NRXN3 RNF39	7.20e-06	184	112	6	575de705053da8b289670b5c40c1627c0833b5ed
ToppCell	facs-Trachea-18m-Epithelial-airway_epithelial-respiratory_basal_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT8 KRT14 IRX5 DSP CLDN3 RAPGEFL1	7.20e-06	184	112	6	2cc2646dee3c6001f7c10b7449c17d1935021958
ToppCell	droplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 KRT14 IRX5 DSP CLDN3 IRX2	7.20e-06	184	112	6	7cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCell	droplet-Lung-nan-21m-Epithelial-Club_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 KRT14 IRX5 DSP CLDN3 IRX2	7.20e-06	184	112	6	53b71c4ac86dc5e42763b8f64fbc917177531017
ToppCell	facs-Heart-LV-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 CLDN3 ERN2 ASCL2 RNF39 BAIAP2L2	7.43e-06	185	112	6	a835f821a5e6568d648df831ec4c2d0048d67093
ToppCell	facs-Heart-LV-24m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 CLDN3 ERN2 ASCL2 RNF39 BAIAP2L2	7.43e-06	185	112	6	386b08bcb304db543e3c5ff75f85e99bf0c592df
ToppCell	Control-Epithelial_alveolar-AT_2-AT2_Progenitor\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRX5 DSP CLDN3 LGALS3 NRXN3 IRX2	7.43e-06	185	112	6	8ca1374501eca01d8468130b74d50abfd4329fbe
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAPT BCAS3 ARHGEF17 NRXN3 KANK3 TANC1	7.43e-06	185	112	6	a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell	Control-Epithelial_alveolar\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IRX5 DSP CLDN3 LGALS3 NRXN3 IRX2	7.43e-06	185	112	6	3937e026add96a396122139daf8011cfbc60e75c
ToppCell	facs-BAT-Fat-24m-Epithelial-Epcam+\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLDN3 ERN2 ADRA2A ASCL2 RNF39 BAIAP2L2	7.66e-06	186	112	6	b18d7398279a2d42414318aeb70514fd402f5a0a
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT8 IRX5 DSP CLDN3 IRX2 RAPGEFL1	7.90e-06	187	112	6	380c3e0bc73b266718893a3b3ca207ce5fd31883
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	DSP GLIS3 CUBN ERN2 NRXN3 RNF39	7.90e-06	187	112	6	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	E12.5-Epithelial\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KRT8 IRX5 CLDN3 CLDN9 CTNND2 IRX2	7.90e-06	187	112	6	29ea5e14dac3321df76f6aa4f053068b49c4a4bf
ToppCell	droplet-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 IRX5 DSP CLDN3 IRX2 RAPGEFL1	7.90e-06	187	112	6	5b3c3c6421efd25c740ae121968b5520bbdc07b2
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 DSP CLDN3 CTNND2 IRX2	7.90e-06	187	112	6	c2940aec30b3c2c113f6a65126dc6f1969cf301e
ToppCell	E12.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KRT8 IRX5 CLDN3 CLDN9 IRX2 TRIB1	7.90e-06	187	112	6	baff4edc1bf64e3e03864a434fa47075ff7372fd
ToppCell	droplet-Lung-LUNG-1m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 IRX5 DSP CLDN3 C2orf81 IRX2	7.90e-06	187	112	6	6288da8cdd450c58df00ebcfcc118f01fab7e610
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	KRT8 IRX5 CLDN3 CLDN9 CTNND2 IRX2	7.90e-06	187	112	6	ab6f4d387218b4651fdadbf269806c1ddc96a1d2
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT8 IRX5 DSP CLDN3 IRX2 RAPGEFL1	7.90e-06	187	112	6	796046ff066a9c3847faa9bf1f8beccd956c01f7
ToppCell	3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-EECs\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KRT8 DSP CLDN3 LGALS3 ASCL2 BAIAP2L2	8.14e-06	188	112	6	ed074572e61d97c139fb1636a78c9b71e2c44ce0
ToppCell	367C-Epithelial_cells-Epithelial-H_(AT1)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	COL7A1 KRT8 CLDN3 IGSF9 RNF39 IRX2	8.14e-06	188	112	6	61422c7919ca0ea02d6be4302f11b169a3ce35e5
ToppCell	367C-Epithelial_cells-Epithelial-H_(AT1)\|367C / Donor, Lineage, Cell class and subclass (all cells)	COL7A1 KRT8 CLDN3 IGSF9 RNF39 IRX2	8.14e-06	188	112	6	18698f0b22ccbc2b93759acc1c8dbdb30a6b5a16
ToppCell	PCW_10-12-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 CLDN3 CLDN9 CTNND2 IRX2	8.14e-06	188	112	6	3cfba3addcc9058f4ec31ad96261f79988f551a0
ToppCell	wk_15-18-Epithelial-Airway_epithelial_progenitor-epi-stalk_early\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KRT8 IRX5 DSP IGSF9 CTNND2 IRX2	8.39e-06	189	112	6	a6c62b456982067ad4d224a2efa3919969000693
ToppCell	droplet-Lung-1m-Epithelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT8 IRX5 DSP CLDN3 C2orf81 IRX2	8.39e-06	189	112	6	72ecd5a10e419bac475e22f5b602e7f008835ce9
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT8 KRT14 DSP CLDN3 IRX2 BAIAP2L2	8.39e-06	189	112	6	ee15b4fb3a1cfda80bcf210a23f04f242594015e
ToppCell	facs-Trachea-24m-Epithelial-airway_epithelial-respiratory_basal_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT8 KRT14 DSP CLDN3 IRX2 BAIAP2L2	8.39e-06	189	112	6	dc6f6fae84347d145bea71b49eaeeb3028e9c4ae
ToppCell	facs-Heart-LV-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKP4 SH2D3C RAPGEF1 KANK3 PPP1R16B AFDN	8.39e-06	189	112	6	d424d2554595b2304219f7324406b401711af7c2
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	IRX5 DSP CLDN3 NRXN3 CTNND2 IRX2	8.39e-06	189	112	6	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	18-Airway-Epithelial-Submucosal_gland\|Airway / Age, Tissue, Lineage and Cell class	KRT8 KRT14 DSP CLDN3 ERN2 IRX2	8.39e-06	189	112	6	c1ea2dc44cf5340378e56e0ffc2e6f64e6c95a58
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKP4 SH2D3C RAPGEF1 KANK3 PPP1R16B AFDN	8.39e-06	189	112	6	393ec5954a12d6cf67bb435dcc34ff0b14c81e9f
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SH2D3C THSD1 IGF1 NRXN3 KANK3 PPP1R16B	8.39e-06	189	112	6	55a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell	facs-Heart-LV-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PKP4 SH2D3C RAPGEF1 KANK3 PPP1R16B AFDN	8.39e-06	189	112	6	bec57459ad4bab15b2532b57722549fec2e771fb
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	IRX5 DSP CLDN3 NRXN3 CTNND2 IRX2	8.65e-06	190	112	6	c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCell	IPF-Epithelial-Goblet\|World / Disease state, Lineage and Cell class	KRT8 GLIS3 CLDN3 ERN2 NRXN3 RNF39	8.65e-06	190	112	6	c29dabf0826663b9d6df51a7af9b76592090e44c
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	KRT8 DSP CLDN3 CLDN9 CTNND2 IRX2	8.91e-06	191	112	6	63aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCell	15-Airway-Epithelial-Secretory_progenitor\|Airway / Age, Tissue, Lineage and Cell class	KRT8 IRX5 CLDN3 CLDN9 IRX2 TRIB1	8.91e-06	191	112	6	9359d8c6b00f8977848986baf3c950157adf4c9a
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	FLNB PKP4 SH2D3C MYRIP RAPGEF1 PPP1R16B	8.91e-06	191	112	6	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLNB PKP4 MYRIP THSD1 PPP1R16B CTNND2	9.18e-06	192	112	6	0aeb5351275c0a91151ea2d52b2cdde172da6731
Computational	Intermediate filaments and MT.	KRT8 KRT14 SNPH DSP MAPT PKP4	5.31e-06	68	71	6	MODULE_438
Computational	Genes in the cancer module 68.	VIM KRT8 KRT14 DSP	2.34e-05	26	71	4	MODULE_68
Disease	monocyte count	FLNB TCF3 ZC3H12A CEBPE FXR2 BCAS3 SH2D3C GLIS3 WNK1 WDR91 ASCL2 ZMIZ2 GPR156 IRS2 TRIB1 RAPGEFL1	3.49e-05	1320	111	16	EFO_0005091
Disease	Pitt-Hopkins syndrome (implicated_via_orthology)	TCF3 TCF12	4.20e-05	3	111	2	DOID:0060488 (implicated_via_orthology)
Disease	Parkinson disease	HTRA2 MAPT ATP13A2	7.57e-05	22	111	3	cv:C0030567
Disease	Sensorineural Hearing Loss (disorder)	IRX5 GLIS3 LHX3	8.69e-05	23	111	3	C0018784
Disease	red blood cell density measurement	MAPT BCAS3 PKP4 LHX3 WNK1 PHC2 KLF1 AFDN IRS2 MAML2 TRIB1 WIPI2	1.21e-04	880	111	12	EFO_0007978
Disease	DiGeorge syndrome (is_implicated_in)	DVL1P1 DVL1	1.39e-04	5	111	2	DOID:11198 (is_implicated_in)
Disease	Autosomal Dominant Parkinsonism	HTRA2 MAPT ATP13A2	1.58e-04	28	111	3	C0752098
Disease	Autosomal Dominant Juvenile Parkinson Disease	HTRA2 MAPT ATP13A2	1.58e-04	28	111	3	C0752097
Disease	Parkinsonism, Experimental	HTRA2 MAPT ATP13A2	1.58e-04	28	111	3	C0752101
Disease	Autosomal Recessive Parkinsonism	HTRA2 MAPT ATP13A2	1.58e-04	28	111	3	C0752100
Disease	Familial Juvenile Parkinsonism	HTRA2 MAPT ATP13A2	1.58e-04	28	111	3	C0752104
Disease	Ramsay Hunt Paralysis Syndrome	HTRA2 MAPT ATP13A2	1.58e-04	28	111	3	C0242423
Disease	PARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE	HTRA2 MAPT ATP13A2	1.58e-04	28	111	3	C1868675
Disease	obsolete_red blood cell distribution width	VIM ZC3H12A FOXK2 FXR2 BCAS3 LARP1 LHX3 WNK1 GRSF1 LGALS3 GAREM2 KLF1 AFDN IRS2 TRIB1	1.60e-04	1347	111	15	EFO_0005192
Disease	Parkinsonism, Juvenile	HTRA2 MAPT ATP13A2	1.95e-04	30	111	3	C0752105
Disease	Parkinsonian Disorders	HTRA2 MAPT ATP13A2	1.95e-04	30	111	3	C0242422
Disease	nicotine dependence	DVL1P1 DVL1 GLIS3 TANC1	2.18e-04	78	111	4	EFO_0003768
Disease	albuminuria	CUBN PHC2 TRIB1 BAHCC1	4.46e-04	94	111	4	EFO_0004285
Disease	amnestic disorder (implicated_via_orthology)	MAPT IRS2	4.96e-04	9	111	2	DOID:10914 (implicated_via_orthology)
Disease	longitudinal alcohol consumption measurement	ADRA2A IGSF9B	4.96e-04	9	111	2	EFO_0007645
Disease	forced expiratory volume	BCAS3 GLIS3 LARP1 LHX3 ARHGEF17 IGF1 NRXN3 SEC24C MYPN CTNND2	8.02e-04	789	111	10	EFO_0004314
Disease	developmental disorder of mental health (implicated_via_orthology)	TCF3 TCF12 TANC1	8.42e-04	49	111	3	DOID:0060037 (implicated_via_orthology)
Disease	triacylglycerol 58:12 measurement	E2F3 NRXN3	9.03e-04	12	111	2	EFO_0010439
Disease	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	TCF3 ATF7IP	9.03e-04	12	111	2	C0023485
Disease	lung carcinoma, estrogen-receptor negative breast cancer, ovarian endometrioid carcinoma, colorectal cancer, prostate carcinoma, ovarian serous carcinoma, breast carcinoma, ovarian carcinoma, lung adenocarcinoma, squamous cell lung carcinoma	KRT8 DVL1P1 DVL1	1.00e-03	52	111	3	EFO_0000305, EFO_0000571, EFO_0000708, EFO_0001071, EFO_0001075, EFO_0001663, EFO_1000650, EFO_1001515, EFO_1001516, MONDO_0005575
Disease	HOMA-B	GLIS3 ADRA2A NAV3	1.18e-03	55	111	3	EFO_0004469
Disease	creatinine measurement	USP45 TCF12 BCAS3 GLIS3 E2F3 LHX3 CUBN PHC2 SLF2 MYPN TRIB1	1.33e-03	995	111	11	EFO_0004518
Disease	t-tau measurement	MAPT BCAS3 GLIS3 NRXN3	1.33e-03	126	111	4	EFO_0004760
Disease	thyroid stimulating hormone measurement	FOXK2 BCAS3 GLIS3 RAPGEF1 PHC2 NRXN3	1.42e-03	323	111	6	EFO_0004748
Disease	caffeine measurement	LAMB2 MAML2	1.43e-03	15	111	2	EFO_0021177
Disease	fibroblast growth factor basic measurement	CLCC1 NRXN3 NAV3	1.44e-03	59	111	3	EFO_0008130
Disease	hypertrophic cardiomyopathy (is_marker_for)	DSP IGF1	1.84e-03	17	111	2	DOID:11984 (is_marker_for)
Disease	Neoplastic Cell Transformation	VIM KRT14 LGALS3 CTNND2	1.91e-03	139	111	4	C0007621
Disease	reticulocyte count	FLNB FOXK2 MAPT BCAS3 LARP1 KLF1 KANK3 IRS2 RNF39 TRIB1 WIPI2	1.96e-03	1045	111	11	EFO_0007986
Disease	schizophrenia, intelligence, self reported educational attainment	SNX29 LGALS3 ATF7IP PPP1R16B IGSF9B MAML2	2.01e-03	346	111	6	EFO_0004337, EFO_0004784, MONDO_0005090
Disease	opioid dependence	KRT8 ZNF326 RAPGEF1 NRXN3 CTNND2	2.06e-03	237	111	5	EFO_0005611
Disease	kidney volume	BCAS3 RAPGEF1	2.06e-03	18	111	2	EFO_0600044
Disease	reticulocyte measurement	FLNB FOXK2 MAPT LARP1 KLF1 KANK3 AFDN IRS2 GNL1 TRIB1 WIPI2	2.08e-03	1053	111	11	EFO_0010700
Disease	adenosine diphosphate measurement	SNX29 PCDH11X	2.55e-03	20	111	2	EFO_0010452
Disease	autism spectrum disorder (implicated_via_orthology)	FXR2 PKP4 NRXN3 CTNND2	2.64e-03	152	111	4	DOID:0060041 (implicated_via_orthology)
Disease	susceptibility to mumps measurement	IGF1 NRXN3 GNL1	2.87e-03	75	111	3	EFO_0008404
Disease	Paroxysmal atrial fibrillation	UBE4B MAPT LHX3 MYPN	2.90e-03	156	111	4	C0235480
Disease	prostate cancer (is_marker_for)	TCF3 HTRA2 E2F3 KMT2D	2.90e-03	156	111	4	DOID:10283 (is_marker_for)
Disease	familial atrial fibrillation	UBE4B MAPT LHX3 MYPN	2.90e-03	156	111	4	C3468561
Disease	Persistent atrial fibrillation	UBE4B MAPT LHX3 MYPN	2.90e-03	156	111	4	C2585653
Disease	Alzheimer's disease (is_marker_for)	VIM HTRA2 MAPT IGF1 IRS2	2.92e-03	257	111	5	DOID:10652 (is_marker_for)
Disease	Parkinson's disease (is_implicated_in)	HTRA2 MAPT ATP13A2	2.98e-03	76	111	3	DOID:14330 (is_implicated_in)
Disease	body surface area	LHX3 WNK1 ATP13A2 IGF1 NRXN3 SLF2 GPR156 TRIB1	3.01e-03	643	111	8	EFO_0022196
Disease	Autosomal Recessive Primary Microcephaly	NCAPD3 ANKLE2	3.08e-03	22	111	2	C3711387
Disease	osteoporosis (biomarker_via_orthology)	IGF1 IRS2	3.08e-03	22	111	2	DOID:11476 (biomarker_via_orthology)
Disease	phosphatidylcholine 34:3 measurement	GLIS3 SNX29	3.08e-03	22	111	2	EFO_0010377
Disease	lean body mass	SNPH FOXK2 PHC2 IGF1 SLF2 TRIB1	3.15e-03	379	111	6	EFO_0004995
Disease	Atrial Fibrillation	UBE4B MAPT LHX3 MYPN	3.18e-03	160	111	4	C0004238
Disease	generalized anxiety disorder	MAPT IGSF9B	3.37e-03	23	111	2	EFO_1001892
Disease	pyruvate measurement	SLC10A3 ERN2 NAV3 PPP1R16B CTNND2	3.49e-03	268	111	5	EFO_0010117

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPSYVISTGVSPSRG	PKP4	221	Q99569
PSPGGKSAYASGTTA	AFDN	1181	P55196
SGPSSSPPEQAYRGS	BAHCC1	91	Q9P281
SLASSYAPFVGGTGP	BAHCC1	2191	Q9P281
GPHSYSPGRNSVAGS	ANKLE2	891	Q86XL3
GPEGSRAASRGSYNP	CEBPE	126	Q15744
SSPPGRDSLYASGAN	ADGRL1	1376	O94910
PGDYSTTPGGTLFST	EIF4EBP1	31	Q13541
GSPGPITRHGSYDSL	BCAS3	696	Q9H6U6
GTYRTSTAPSSPGVD	CTNND2	451	Q9UQB3
GRGGSSEPGSPRSAY	ASCL2	151	Q99929
PTSPVYRGSSSGPSS	MTUS2	1346	Q5JR59
YRGSSSGPSSPARVS	MTUS2	1351	Q5JR59
CSSGTGQPYGPTFTT	RANBP10	151	Q6VN20
LRGPLSHFYSGSPTS	RAVER1	476	Q8IY67
AGGPSAESPRPSSAY	EDC4	26	Q6P2E9
LGRSSSGSAFSPYAG	IRX5	36	P78411
SPYAGSTAFTAPSPG	IRX5	46	P78411
PFYSAAGSIPSGVSG	GRSF1	31	Q12849
GPRAFSSRSYTSGPG	KRT8	16	P05787
RGLQGPGLGYPTSST	KIAA1549	1901	Q9HCM3
SFPSYLASPAGSRGS	ARHGEF17	376	Q96PE2
NRGICGTSYPTTSPG	DSG3	591	P32926
SPSEGTPTVGSYGCT	LARP1	851	Q6PKG0
RRTGGPAYGPSSDVS	FXR2	436	P51116
PSSPRGAGSSGYKVG	FOXK2	211	Q01167
RAPSTYGGGLSVSSS	KRT14	41	P02533
REGSPSTAVRYPSGS	ERN2	336	Q76MJ5
SSGQPSATGAYPATG	LGALS3	91	P17931
GSGSYGTEPDARPAS	BAIAP2L2	271	Q6UXY1
RPTYGSLPGGAESDS	FSIP2	1711	Q5CZC0
TASGPGLSSYGVPAS	FLNB	1521	O75369
STAGGHTVPPTGGRY	SLC10A3	51	P09131
APSLGAGYPRSGTSR	NAV3	756	Q8IVL0
GTSGQPSPSYDSSRG	TCF12	61	Q99081
FYVGGSPSTADLPGS	NRXN3	381	Q9Y4C0
PTTGSLRLYGGGTSF	KRT25	16	Q7Z3Z0
VRTGGSAQPETPYSG	LAMB2	696	P55268
PSSDLSTGSSGGYPD	LHX3	366	Q9UBR4
STGSSGGYPDFPASP	LHX3	371	Q9UBR4
TSAPGSSLAGRNPYA	GNL1	586	P36915
GSLTSTSHGLPLGYP	PCDH11X	1076	Q9BZA7
LARSASGSAFSPYPG	IRX2	36	Q9BZI1
SAGVRFPTGTPAAYT	MAML2	981	Q8IZL2
GKAPLIGGRTSPYSS	PPP1R16B	516	Q96T49
PASGGGYKASSPAES	IRS2	721	Q9Y4H2
SGATGSFSSPGFPNR	CUBN	1396	O60494
SPLVGSTPTGYGTLT	ATP13A2	6	Q9NQ11
SGTSDPRARVTYGTP	HTRA2	41	O43464
GSSGGYFPRTGLSVP	KLF1	176	Q13351
SGSSSYGRLGPSEPR	DACT3	141	Q96B18
GSLLYTTPHGPSSRA	E2F3	96	O00716
GGGLLGPSHSYSSSP	DMBX1	246	Q8NFW5
SGYGPPSSHSSSRVV	CELA3A	16	P09093
PYNMSSAPGSRSGSR	DSP	2816	P15924
NYSSRSGTAAGAVPP	GLIS3	561	Q8NEA6
TVGPSGLYSPSTNRG	ATF7IP	891	Q6VMQ6
TSGPSSYAQSLEGPG	GPR156	446	Q8NFN8
VPAAGGARSPSSPYS	KANK3	21	Q6NY19
SYPSVGGATRPSASC	C2orf81	301	A6NN90
SGSRPLPSYAADTAG	COL7A1	2811	Q02388
TGALPRYGTSPCSSA	DVL1	371	O14640
PTGYGSSSRRAPQTG	IGF1	76	P05019
PRGFSLYTGSSGALS	EMILIN1	26	Q9Y6C2
RGSSPRSQASSYAPG	DVL1P1	601	P54792
GSSSSVYRLGSAPGP	ETV3L	196	Q6ZN32
SSYGGQSGSTAPAIP	SEC24C	26	P53992
GSLTSTSHGLPLGYP	PCDH11Y	1071	Q9BZA8
RTTSGPVATSGPAYS	GAREM2	651	Q75VX8
SSVGYRVPAGSGPSL	RIN1	291	Q13671
SGVGSYSPADAPLGS	SNX29	406	Q8TEQ0
TGRFPDYPDASSGGS	IQCA1L	311	A6NCM1
APPGNRSSASGYGSR	SLTM	916	Q9NWH9
GAYTVRPSSGPHGSQ	SH2D6	86	Q7Z4S9
SAGDGPVPYSQGSSS	TANC1	291	Q9C0D5
SGPPISGFSVGSTYD	PRRC1	126	Q96M27
GAAAGKGTYVPSSPT	WIPI2	401	Q9Y4P8
SGGPLRSEYGTPTKS	SLF2	541	Q8IX21
GSYKGSDSSPTPRRS	SNPH	41	O15079
LRSSASPGIGTPFSY	NPTX2	256	P47972
TEAPGGGARATPYSL	ADRA2A	31	P08913
VVYSAPRSTGPGASL	CLDN3	196	O15551
PRSTGPGASLGTGYD	CLDN3	201	O15551
PRLGYSIPSRSGASG	CLDN9	196	O95484
GAGVSYIGTPRTPSS	NCAPD3	1426	P42695
AAGSPDQGSTYSPAR	CLCC1	521	Q96S66
GSGRPTGPQISVYSG	PHC2	36	Q8IXK0
AGTSNSGSGALPPYA	ZC3H6	1011	P61129
QTYAPSGRSLAPSGG	ZC3H12A	396	Q5D1E8
RSSSGSGVQPDGPLY	USP45	521	Q70EL2
GSGSAPGPSRIADYL	TRIB1	81	Q96RU8
TPSPASLGDGAPYGS	ZFHX2	801	Q9C0A1
GGSHSYGGESPRLSP	RAPGEF1	336	Q13905
SRPPDSYSGLGRAGA	TCF3	476	P15923
GSPSQSSRSGSPSYR	IGSF9B	1256	Q9UPX0
DTSSGGPARAYPVGG	SEC61A1	326	P61619
SLGSDSELSGPGPYR	TBC1D10C	21	Q8IV04
TARGTAAPGEGPVYS	ROBO3	1006	Q96MS0
TGSPGDTGIPLTYRR	THSD1	486	Q9NS62
ASGTAAGSQPSSPRY	UBE4B	316	O95155
SRPASLGYSGAAGPR	UBL7	251	Q96S82
GGPGTASRPSSSRSY	VIM	16	P08670
PSTSRSLYASSPGGV	VIM	46	P08670
SSGEPPKSGDRSGYS	MAPT	501	P10636
TFLGTGAAYPSPTRG	ELAC1	6	Q9H777
PSAGGSYLSPAPGDT	IGSF9	1041	Q9P2J2
GSVSYSQPGLSGPTR	ZMIZ2	346	Q8NF64
SYGLGQGSSKPASPV	SH2D3C	331	Q8N5H7
SSPGAGVSSYISQPG	WNK1	1551	Q9H4A3
GGGPLRSPSSYSSDE	RAPGEFL1	116	Q9UHV5
PSDATGPFVLSGYSG	WDR91	646	A4D1P6
GPPSKAYCRGGSSST	nan	136	Q96M66
SSSSSGGGLLPYPRR	ZFC3H1	41	O60293
GIYTASSRGGPPSAR	RNF39	36	Q9H2S5
GSRGRGTPAYPESTF	ZNF326	171	Q5BKZ1
GGSTLSSAASGLAPY	GARIN5B	351	Q8N5Q1
GSPLGPSSGSTGESY	KMT2D	2591	O14686
PSSGSTGESYGLSPL	KMT2D	2596	O14686
AGGDTTPGSSPSSLY	MYPN	246	Q86TC9
GTSASPGGYRAPAAL	MYRIP	276	Q8NFW9