Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	TNIK CDC42BPA TRIO CAMKV KALRN NEK5 MARK3 MINK1 MAP4K4	1.18e-05	446	64	9	GO:0004674
GeneOntologyMolecularFunction	protein kinase activity	TNIK CDC42BPA TRIO CAMKV KALRN NEK5 MARK3 MINK1 RET MAP4K4	1.96e-05	600	64	10	GO:0004672
GeneOntologyMolecularFunction	protein serine kinase activity	TNIK CDC42BPA TRIO KALRN NEK5 MARK3 MINK1 MAP4K4	2.01e-05	363	64	8	GO:0106310
GeneOntologyMolecularFunction	group III metabotropic glutamate receptor activity	GRM4 GRM8	6.04e-05	4	64	2	GO:0001642
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	TNIK CDC42BPA TRIO CAMKV KALRN NEK5 MARK3 MINK1 RET MAP4K4	8.00e-05	709	64	10	GO:0016773
GeneOntologyMolecularFunction	kinase activity	TNIK CDC42BPA TRIO CAMKV KALRN NEK5 MARK3 MINK1 RET MAP4K4	1.48e-04	764	64	10	GO:0016301
GeneOntologyMolecularFunction	G protein-coupled glutamate receptor activity	GRM4 GRM8	3.59e-04	9	64	2	GO:0098988
GeneOntologyMolecularFunction	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	GRM4 GRM8	3.59e-04	9	64	2	GO:0001640
GeneOntologyMolecularFunction	phosphorylation-dependent protein binding	ANK2 ANK3	4.48e-04	10	64	2	GO:0140031
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	TNIK CDC42BPA TRIO CAMKV KALRN NEK5 MARK3 MINK1 RET MAP4K4	7.52e-04	938	64	10	GO:0016772
GeneOntologyMolecularFunction	coreceptor activity	CXCR4 LRP5 RECK	1.60e-03	72	64	3	GO:0015026
GeneOntologyMolecularFunction	peroxisome proliferator activated receptor binding	CREBBP RPL11	2.04e-03	21	64	2	GO:0042975
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	ZNF131 KMT2D MGA ZNF786 MYB ZNF292 ZNF445	2.05e-03	560	64	7	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	ZNF131 KMT2D MGA ZNF786 MYB ZNF292 ZNF445	2.18e-03	566	64	7	GO:0001216
GeneOntologyMolecularFunction	cytoskeletal anchor activity	ANK2 ANK3	2.67e-03	24	64	2	GO:0008093
GeneOntologyMolecularFunction	glutamate receptor activity	GRM4 GRM8	3.37e-03	27	64	2	GO:0008066
GeneOntologyCellularComponent	asymmetric synapse	TNIK ANK2 ANK3 KALRN PCLO MINK1 MIB1 ITGA8 GRM4	1.60e-05	477	65	9	GO:0032279
GeneOntologyCellularComponent	neuron to neuron synapse	TNIK ANK2 ANK3 KALRN PCLO MINK1 MIB1 ITGA8 GRM4	3.30e-05	523	65	9	GO:0098984
GeneOntologyCellularComponent	glutamatergic synapse	TNIK TRIO CAMKV KALRN PCLO MIB1 DOCK10 ITGA8 SPARCL1 GRM4 GRM8	3.95e-05	817	65	11	GO:0098978
GeneOntologyCellularComponent	postsynapse	TNIK ANK2 ANK3 TRIO CAMKV KALRN PCLO MINK1 MIB1 DOCK10 ITGA8 RPS16	6.15e-05	1018	65	12	GO:0098794
GeneOntologyCellularComponent	postsynaptic density	TNIK ANK2 ANK3 KALRN PCLO MINK1 MIB1 ITGA8	7.59e-05	451	65	8	GO:0014069
GeneOntologyCellularComponent	postsynaptic specialization	TNIK ANK2 ANK3 KALRN PCLO MINK1 MIB1 ITGA8	1.61e-04	503	65	8	GO:0099572
GeneOntologyCellularComponent	somatodendritic compartment	FLNB ANK3 KALRN MARK3 PCLO MINK1 DOCK10 ITGA8 RET GRM4 GRM8 TF	3.56e-04	1228	65	12	GO:0036477
GeneOntologyCellularComponent	presynaptic active zone	TRIO PCLO GRM4 GRM8	9.76e-04	141	65	4	GO:0048786
GeneOntologyCellularComponent	Wnt signalosome	LRP5 RECK	1.11e-03	16	65	2	GO:1990909
GeneOntologyCellularComponent	dendrite	ANK3 MARK3 PCLO MINK1 DOCK10 ITGA8 RET GRM4 TF	1.29e-03	858	65	9	GO:0030425
GeneOntologyCellularComponent	dendritic tree	ANK3 MARK3 PCLO MINK1 DOCK10 ITGA8 RET GRM4 TF	1.31e-03	860	65	9	GO:0097447
GeneOntologyCellularComponent	histone methyltransferase complex	KMT2D WDR5B MGA	1.65e-03	75	65	3	GO:0035097
GeneOntologyCellularComponent	costamere	ANK2 ANK3	2.11e-03	22	65	2	GO:0043034
Domain	CNH	TNIK CDC42BPA MINK1 MAP4K4	1.30e-07	14	65	4	SM00036
Domain	CNH	TNIK CDC42BPA MINK1 MAP4K4	1.77e-07	15	65	4	PF00780
Domain	CNH	TNIK CDC42BPA MINK1 MAP4K4	1.77e-07	15	65	4	PS50219
Domain	CNH_dom	TNIK CDC42BPA MINK1 MAP4K4	1.77e-07	15	65	4	IPR001180
Domain	S_TKc	TNIK CDC42BPA TRIO CAMKV KALRN NEK5 MARK3 MINK1 MAP4K4	4.01e-06	359	65	9	SM00220
Domain	Pkinase	TNIK CDC42BPA TRIO CAMKV KALRN NEK5 MARK3 MINK1 MAP4K4	6.49e-06	381	65	9	PF00069
Domain	Prot_kinase_dom	TNIK CDC42BPA TRIO CAMKV KALRN NEK5 MARK3 MINK1 RET MAP4K4	6.80e-06	489	65	10	IPR000719
Domain	PROTEIN_KINASE_DOM	TNIK CDC42BPA TRIO CAMKV KALRN NEK5 MARK3 MINK1 RET MAP4K4	7.30e-06	493	65	10	PS50011
Domain	Kinase-like_dom	TNIK CDC42BPA TRIO CAMKV KALRN NEK5 MARK3 MINK1 RET MAP4K4	1.66e-05	542	65	10	IPR011009
Domain	PROTEIN_KINASE_ATP	TNIK CDC42BPA TRIO KALRN NEK5 MARK3 MINK1 RET MAP4K4	2.85e-05	459	65	9	PS00107
Domain	Ser/Thr_kinase_AS	TNIK CDC42BPA TRIO KALRN NEK5 MARK3 MINK1 MAP4K4	3.22e-05	357	65	8	IPR008271
Domain	PROTEIN_KINASE_ST	TNIK CDC42BPA TRIO KALRN NEK5 MARK3 MINK1 MAP4K4	3.55e-05	362	65	8	PS00108
Domain	PLAC	ADAMTS12 ADAMTS19 ADAMTS14	3.75e-05	19	65	3	PS50900
Domain	PLAC	ADAMTS12 ADAMTS19 ADAMTS14	3.75e-05	19	65	3	IPR010909
Domain	Protein_kinase_ATP_BS	TNIK CDC42BPA KALRN NEK5 MARK3 MINK1 RET MAP4K4	4.91e-05	379	65	8	IPR017441
Domain	ADAM_spacer1	ADAMTS12 ADAMTS19 ADAMTS14	6.78e-05	23	65	3	IPR010294
Domain	ADAM_spacer1	ADAMTS12 ADAMTS19 ADAMTS14	6.78e-05	23	65	3	PF05986
Domain	Peptidase_M12B_ADAM-TS	ADAMTS12 ADAMTS19 ADAMTS14	7.73e-05	24	65	3	IPR013273
Domain	GPCR_3_mtglu_rcpt	GRM4 GRM8	3.29e-04	8	65	2	IPR000162
Domain	Peptidase_M12B_N	ADAMTS12 ADAMTS19 ADAMTS14	3.36e-04	39	65	3	IPR002870
Domain	Pep_M12B_propep	ADAMTS12 ADAMTS19 ADAMTS14	3.36e-04	39	65	3	PF01562
Domain	DISINTEGRIN_1	ADAMTS12 ADAMTS19 ADAMTS14	3.63e-04	40	65	3	PS00427
Domain	Reprolysin	ADAMTS12 ADAMTS19 ADAMTS14	3.63e-04	40	65	3	PF01421
Domain	ADAM_MEPRO	ADAMTS12 ADAMTS19 ADAMTS14	3.63e-04	40	65	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS12 ADAMTS19 ADAMTS14	3.63e-04	40	65	3	PS50214
Domain	Peptidase_M12B	ADAMTS12 ADAMTS19 ADAMTS14	3.63e-04	40	65	3	IPR001590
Domain	CYSTEINE_SWITCH	ADAMTS12 ADAMTS19 ADAMTS14	3.90e-04	41	65	3	PS00546
Domain	Disintegrin_dom	ADAMTS12 ADAMTS19 ADAMTS14	3.90e-04	41	65	3	IPR001762
Domain	ZU5	ANK2 ANK3	4.23e-04	9	65	2	SM00218
Domain	Pept_M10_metallopeptidase	ADAMTS12 ADAMTS19 ADAMTS14	4.49e-04	43	65	3	IPR001818
Domain	ZU5	ANK2 ANK3	5.27e-04	10	65	2	PS51145
Domain	ZU5	ANK2 ANK3	7.70e-04	12	65	2	PF00791
Domain	ZU5_dom	ANK2 ANK3	7.70e-04	12	65	2	IPR000906
Domain	NCD3G	GRM4 GRM8	9.08e-04	13	65	2	PF07562
Domain	GPCR_3_9-Cys_dom	GRM4 GRM8	9.08e-04	13	65	2	IPR011500
Domain	GPCR_3_CS	GRM4 GRM8	1.06e-03	14	65	2	IPR017979
Domain	TSP_1	ADAMTS12 ADAMTS19 ADAMTS14	1.38e-03	63	65	3	PF00090
Domain	TSP1	ADAMTS12 ADAMTS19 ADAMTS14	1.51e-03	65	65	3	SM00209
Domain	TSP1_rpt	ADAMTS12 ADAMTS19 ADAMTS14	1.51e-03	65	65	3	IPR000884
Domain	TSP1	ADAMTS12 ADAMTS19 ADAMTS14	1.51e-03	65	65	3	PS50092
Domain	ZZ	MIB1 CREBBP	1.76e-03	18	65	2	PF00569
Domain	ZF_ZZ_2	MIB1 CREBBP	1.76e-03	18	65	2	PS50135
Domain	ZF_ZZ_1	MIB1 CREBBP	1.76e-03	18	65	2	PS01357
Domain	Znf_ZZ	MIB1 CREBBP	1.96e-03	19	65	2	IPR000433
Domain	ZnF_ZZ	MIB1 CREBBP	1.96e-03	19	65	2	SM00291
Domain	GPCR_3	GRM4 GRM8	2.40e-03	21	65	2	IPR000337
Domain	CRAL_TRIO	TRIO KALRN	2.40e-03	21	65	2	PF00650
Domain	7tm_3	GRM4 GRM8	2.63e-03	22	65	2	PF00003
Domain	G_PROTEIN_RECEP_F3_2	GRM4 GRM8	2.63e-03	22	65	2	PS00980
Domain	G_PROTEIN_RECEP_F3_3	GRM4 GRM8	2.63e-03	22	65	2	PS00981
Domain	G_PROTEIN_RECEP_F3_1	GRM4 GRM8	2.63e-03	22	65	2	PS00979
Domain	G_PROTEIN_RECEP_F3_4	GRM4 GRM8	2.63e-03	22	65	2	PS50259
Domain	GPCR_3_C	GRM4 GRM8	2.63e-03	22	65	2	IPR017978
Domain	MetalloPept_cat_dom	ADAMTS12 ADAMTS19 ADAMTS14	2.83e-03	81	65	3	IPR024079
Domain	-	ADAMTS12 ADAMTS19 ADAMTS14	2.83e-03	81	65	3	3.40.390.10
Domain	-	TRIO KALRN	2.88e-03	23	65	2	3.40.525.10
Domain	Spectrin	TRIO KALRN	2.88e-03	23	65	2	PF00435
Domain	SEC14	TRIO KALRN	3.40e-03	25	65	2	SM00516
Domain	ACR	ADAMTS19 ADAMTS14	3.96e-03	27	65	2	SM00608
Pathway	WP_HIPPOYAP_SIGNALING	TNIK MINK1 MAP4K4	5.45e-05	22	48	3	M39821
Pathway	WP_WNTBETACATENIN_SIGNALING_INHIBITORS_IN_CURRENT_AND_PAST_CLINICAL_TRIALS	LRP5 CREBBP	1.13e-04	5	48	2	M48304
Pathway	REACTOME_SIGNALING_BY_LRP5_MUTANTS	LRP5 DKK2	1.69e-04	6	48	2	M27432
Pathway	REACTOME_OXIDATIVE_STRESS_INDUCED_SENESCENCE	TNIK MINK1 MAP4K4	2.65e-04	37	48	3	MM14899
Pathway	REACTOME_RAC1_GTPASE_CYCLE	CDC42BPA FAM13A TRIO KALRN DOCK10	3.10e-04	175	48	5	MM15599
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS12 ADAMTS19 ADAMTS14	3.11e-04	39	48	3	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS12 ADAMTS19 ADAMTS14	3.11e-04	39	48	3	MM15165
Pathway	REACTOME_NEGATIVE_REGULATION_OF_TCF_DEPENDENT_SIGNALING_BY_WNT_LIGAND_ANTAGONISTS	LRP5 DKK2	3.14e-04	8	48	2	MM14976
Pathway	PID_EPHB_FWD_PATHWAY	KALRN MAP4K4 TF	3.35e-04	40	48	3	M62
Pathway	REACTOME_RAC1_GTPASE_CYCLE	CDC42BPA FAM13A TRIO KALRN DOCK10	3.90e-04	184	48	5	M41809
Pathway	WP_GENES_CONTROLLING_NEPHROGENESIS	CXCR4 ITGA8 RET	4.45e-04	44	48	3	M39891
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	ANK2 ANK3 TRIO KALRN CXCR4 RPS16 RET RPL11	6.51e-04	575	48	8	M29853
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	LSM12 TNIK FLNB CDC42BPA ANK2 ANK3 TRIO CAMKV KALRN PCLO MINK1 SPARCL1 USP15 MAP4K4 PRKRA	2.74e-09	1139	66	15	36417873
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	FLNB ANK2 ANK3 TRIO KALRN MIB1 SPARCL1 ZBTB11 MAP4K4 TF CREBBP RECK ZNF292 PRKRA	1.06e-07	1285	66	14	35914814
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	FLNB ANK2 ANK3 TRIO CAMKV KALRN MARK3 PCLO MINK1 RPS16 IDH3B TF RPL11 PRKRA	3.90e-07	1431	66	14	37142655
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	TNIK ANK2 ANK3 TRIO KALRN PCLO MINK1	1.08e-06	281	66	7	28706196
Pubmed	Functional proteomics mapping of a human signaling pathway.	FLNB KMT2D ANK3 PPP1R15B LRP5 SPARCL1 ZBTB11 MGA CREBBP	1.74e-06	591	66	9	15231748
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	TNIK PCLO MGA USP15 ZNF292	1.76e-06	105	66	5	9628581
Pubmed	Rap2A links intestinal cell polarity to brush border formation.	TNIK MINK1 MAP4K4	2.92e-06	15	66	3	22797597
Pubmed	MITF - A controls branching morphogenesis and nephron endowment.	CXCR4 RET MYB	2.92e-06	15	66	3	29240767
Pubmed	Vandetanib inhibits cisplatin‑resistant neuroblastoma tumor growth and invasion.	CXCR4 RET	3.55e-06	2	66	2	29436676
Pubmed	Structure of the transition state for the binding of c-Myb and KIX highlights an unexpected order for a disordered system.	CREBBP MYB	3.55e-06	2	66	2	23980173
Pubmed	Increased affinity of c-Myb for CREB-binding protein (CBP) after CBP-induced acetylation.	CREBBP MYB	3.55e-06	2	66	2	11073948
Pubmed	The ankyrin-B C-terminal domain determines activity of ankyrin-B/G chimeras in rescue of abnormal inositol 1,4,5-trisphosphate and ryanodine receptor distribution in ankyrin-B (-/-) neonatal cardiomyocytes.	ANK2 ANK3	3.55e-06	2	66	2	11781319
Pubmed	Structural basis of diverse membrane target recognitions by ankyrins.	ANK2 ANK3	3.55e-06	2	66	2	25383926
Pubmed	Human MRCKalpha is regulated by cellular iron levels and interferes with transferrin iron uptake.	CDC42BPA TF	3.55e-06	2	66	2	20188707
Pubmed	The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by repressing pro-differentiation genes.	ZNF131 ZBTB11	3.55e-06	2	66	2	35294876
Pubmed	Solution structure of the KIX domain of CBP bound to the transactivation domain of c-Myb.	CREBBP MYB	3.55e-06	2	66	2	15019774
Pubmed	A ketogenic diet rescues hippocampal memory defects in a mouse model of Kabuki syndrome.	KMT2D CREBBP	3.55e-06	2	66	2	27999180
Pubmed	Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.	TRIO KALRN	3.55e-06	2	66	2	26858404
Pubmed	Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.	TNIK FLNB PCLO RRP12 RPS16 IDH3B RPL11 PRKRA	4.63e-06	498	66	8	36634849
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	TNIK CDC42BPA ANK3 MARK3 MINK1 DOCK10 MAP4K4	7.48e-06	377	66	7	38117590
Pubmed	Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.	TNIK ANK2 ANK3 TRIO KALRN MINK1	8.42e-06	251	66	6	27507650
Pubmed	Ureteric morphogenesis requires Fgfr1 and Fgfr2/Frs2α signaling in the metanephric mesenchyme.	CXCR4 RET MYB	8.47e-06	21	66	3	22282599
Pubmed	Mitogen-activated protein kinase (MAPK) pathway regulates branching by remodeling epithelial cell adhesion.	CXCR4 RET MYB	8.47e-06	21	66	3	24603431
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	TNIK ANK2 TRIO KALRN SPARCL1	1.04e-05	151	66	5	17043677
Pubmed	Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.	TNIK ANK2 ANK3 TRIO RPS16 MAP4K4 RPL11 PRKRA	1.06e-05	558	66	8	35063084
Pubmed	Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation.	KMT2D CREBBP	1.06e-05	3	66	2	34463256
Pubmed	Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.	TRIO KALRN	1.06e-05	3	66	2	31801062
Pubmed	Structural insight into the mechanisms of Wnt signaling antagonism by Dkk.	LRP5 DKK2	1.06e-05	3	66	2	18524778
Pubmed	Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.	CREBBP MYB	1.06e-05	3	66	2	24340053
Pubmed	A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.	CREBBP MYB	1.06e-05	3	66	2	12384703
Pubmed	Roles of phosphorylation and helix propensity in the binding of the KIX domain of CREB-binding protein by constitutive (c-Myb) and inducible (CREB) activators.	CREBBP MYB	1.06e-05	3	66	2	12196545
Pubmed	The ammonium transporter RhBG: requirement of a tyrosine-based signal and ankyrin-G for basolateral targeting and membrane anchorage in polarized kidney epithelial cells.	ANK2 ANK3	1.06e-05	3	66	2	15611082
Pubmed	Human ankyrins and their contribution to disease biology: An update.	ANK2 ANK3	1.06e-05	3	66	2	33410423
Pubmed	Association between the group III metabotropic glutamate receptor gene polymorphisms and attention-deficit/hyperactivity disorder and functional exploration of risk loci.	GRM4 GRM8	1.06e-05	3	66	2	33068816
Pubmed	Inhibition of cyclin A/Cdk2 phosphorylation impairs B-Myb transactivation function without affecting interactions with DNA or the CBP coactivator.	CREBBP MYB	1.06e-05	3	66	2	11423988
Pubmed	MINK is a Rap2 effector for phosphorylation of the postsynaptic scaffold protein TANC1.	TNIK MINK1	1.06e-05	3	66	2	18930710
Pubmed	KMT2D acetylation by CREBBP reveals a cooperative functional interaction at enhancers in normal and malignant germinal center B cells.	KMT2D CREBBP	1.06e-05	3	66	2	36893259
Pubmed	Group III human metabotropic glutamate receptors 4, 7 and 8: molecular cloning, functional expression, and comparison of pharmacological properties in RGT cells.	GRM4 GRM8	1.06e-05	3	66	2	9473604
Pubmed	Structural basis for cooperative transcription factor binding to the CBP coactivator.	CREBBP MYB	1.06e-05	3	66	2	16253272
Pubmed	Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.	ANK2 ANK3	1.06e-05	3	66	2	34289389
Pubmed	Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney.	CXCR4 RET MYB	1.12e-05	23	66	3	21035938
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TNIK ANK2 ANK3 TRIO CAMKV KALRN MINK1 GRM4 MGA MAP4K4	1.31e-05	963	66	10	28671696
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	LSM12 CDC42BPA ANK3 PPP1R15B MINK1 RPS16 MGA DKK2 RPL11	1.57e-05	777	66	9	35844135
Pubmed	MLL3/MLL4 are required for CBP/p300 binding on enhancers and super-enhancer formation in brown adipogenesis.	KMT2D CREBBP	2.12e-05	4	66	2	28398509
Pubmed	Trans-mesenteric neural crest cells are the principal source of the colonic enteric nervous system.	CXCR4 RET	2.12e-05	4	66	2	22902718
Pubmed	Distribution of group-III metabotropic glutamate receptors in the retina.	GRM4 GRM8	2.12e-05	4	66	2	17311335
Pubmed	Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis.	CXCR4 RET MYB	2.82e-05	31	66	3	19898483
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	LSM12 FLNB FLYWCH2 MIB1 GON4L USP15 CREBBP ZNF687	2.99e-05	645	66	8	25281560
Pubmed	PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.	ANK3 MARK3 MIB1 RET	3.17e-05	94	66	4	32062451
Pubmed	CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.	ANK2 ANK3	3.53e-05	5	66	2	25950943
Pubmed	Assembly of high order G alpha q-effector complexes with RGS proteins.	TRIO KALRN	3.53e-05	5	66	2	18936096
Pubmed	Glial ankyrins facilitate paranodal axoglial junction assembly.	ANK2 ANK3	3.53e-05	5	66	2	25362471
Pubmed	HIV infection of T cells: actin-in and actin-out.	FLNB CXCR4	3.53e-05	5	66	2	19366992
Pubmed	Differential sensitivity of v-Myb and c-Myb to Wnt-1-induced protein degradation.	CREBBP MYB	3.53e-05	5	66	2	15308626
Pubmed	An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.	ANK2 ANK3	3.53e-05	5	66	2	19109891
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	FLNB CDC42BPA ANK2 TRIO KALRN GON4L MGA	4.39e-05	497	66	7	23414517
Pubmed	Identification of multipotent progenitors in the embryonic mouse kidney by a novel colony-forming assay.	SCNN1G ITGA8 RET	4.84e-05	37	66	3	16319116
Pubmed	Pias1 interaction and sumoylation of metabotropic glutamate receptor 8.	GRM4 GRM8	5.29e-05	6	66	2	16144832
Pubmed	The Wnt-NLK signaling pathway inhibits A-Myb activity by inhibiting the association with coactivator CBP and methylating histone H3.	CREBBP MYB	5.29e-05	6	66	2	16055500
Pubmed	The actin-binding protein Filamin-A interacts with the metabotropic glutamate receptor type 7.	GRM4 GRM8	5.29e-05	6	66	2	11943148
Pubmed	Loss of CREBBP and KMT2D cooperate to accelerate lymphomagenesis and shape the lymphoma immune microenvironment.	KMT2D CREBBP	5.29e-05	6	66	2	38570506
Pubmed	In vivo assembly of the axon initial segment in motor neurons.	ANK2 ANK3	5.29e-05	6	66	2	23728480
Pubmed	Oncogenic activation of c-Myb correlates with a loss of negative regulation by TIF1beta and Ski.	CREBBP MYB	5.29e-05	6	66	2	14761981
Pubmed	Localization of two metabotropic glutamate receptor genes, GRM3 and GRM8, to human chromosome 7q.	GRM4 GRM8	5.29e-05	6	66	2	8824806
Pubmed	Diamond-Blackfan anemia: genotype-phenotype correlations in Italian patients with RPL5 and RPL11 mutations.	RPS16 RPL11	5.29e-05	6	66	2	19773262
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	CDC42BPA TRIO MARK3 MINK1 RET IDH3B MAP4K4 CREBBP ZNF687	5.38e-05	910	66	9	36736316
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	FLNB CDC42BPA ANK2 ANK3 MARK3 MINK1 MAP4K4 RPL11	5.75e-05	708	66	8	39231216
Pubmed	Quantitative nanoproteomics for protein complexes (QNanoPX) related to estrogen transcriptional action.	FLNB RPS16 RPL11	6.61e-05	41	66	3	19805454
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	LSM12 TNIK TRIO FLYWCH2 MGA USP15 MAP4K4 ZNF687	7.33e-05	733	66	8	34672954
Pubmed	Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.	ADAMTS19 ADAMTS14	7.40e-05	7	66	2	11867212
Pubmed	The beta-catenin axis integrates multiple signals downstream from RET/papillary thyroid carcinoma leading to cell proliferation.	RET CREBBP	7.40e-05	7	66	2	19223551
Pubmed	Analysis of the role of membrane polarity in polycystic kidney disease of transgenic SBM mice.	ANK2 ANK3	7.40e-05	7	66	2	7495297
Pubmed	Functional characterization of WNT7A signaling in PC12 cells: interaction with A FZD5 x LRP6 receptor complex and modulation by Dickkopf proteins.	LRP5 DKK2	7.40e-05	7	66	2	12857724
Pubmed	OPG and RANK polymorphisms are both associated with cortical bone mineral density: findings from a metaanalysis of the Avon longitudinal study of parents and children and gothenburg osteoporosis and obesity determinants cohorts.	MARK3 LRP5	7.40e-05	7	66	2	20534768
Pubmed	Mitochondrial Hep27 is a c-Myb target gene that inhibits Mdm2 and stabilizes p53.	RPL11 MYB	7.40e-05	7	66	2	20547751
Pubmed	Endoplasmic reticulum stress-activated C/EBP homologous protein enhances nuclear factor-kappaB signals via repression of peroxisome proliferator-activated receptor gamma.	CREBBP MYB	7.40e-05	7	66	2	20829347
Pubmed	DKK2 imparts tumor immunity evasion through β-catenin-independent suppression of cytotoxic immune-cell activation.	LRP5 DKK2	7.40e-05	7	66	2	29431745
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	FLNB KMT2D CDC42BPA MINK1 GON4L	8.45e-05	234	66	5	36243803
Pubmed	Environmental signals rather than layered ontogeny imprint the function of type 2 conventional dendritic cells in young and adult mice.	CXCR4 MYB	9.86e-05	8	66	2	33469015
Pubmed	LZTR1 is a regulator of RAS ubiquitination and signaling.	TNIK MARK3 MINK1 MAP4K4	1.03e-04	127	66	4	30442766
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	TNIK ZNF131 CDC42BPA ANK2 ANK3 MARK3 PPP1R15B RRP12 MINK1 MIB1 MAP4K4	1.04e-04	1487	66	11	33957083
Pubmed	Identification of proteins associated with ligand-activated estrogen receptor α in human breast cancer cell nuclei by tandem affinity purification and nano LC-MS/MS.	FLNB RRP12 RPS16 TF RPL11	1.05e-04	245	66	5	21182205
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FLNB CDC42BPA ANK3 FAM13A TRIO MARK3 MINK1 LRP5 USP15 CREBBP RECK	1.05e-04	1489	66	11	28611215
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	KMT2D PCLO GON4L MGA CREBBP ZNF292	1.10e-04	398	66	6	35016035
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TNIK MARK3 RRP12 DOCK10 GON4L USP15	1.24e-04	407	66	6	12693553
Pubmed	Ank3 (epithelial ankyrin), a widely distributed new member of the ankyrin gene family and the major ankyrin in kidney, is expressed in alternatively spliced forms, including forms that lack the repeat domain.	ANK3 RPS16	1.27e-04	9	66	2	7615634
Pubmed	Potent and specific Atg8-targeting autophagy inhibitory peptides from giant ankyrins.	ANK2 ANK3	1.27e-04	9	66	2	29867141
Pubmed	The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.	RRP12 RPS16 IDH3B USP15 RPL11 PRKRA	1.42e-04	417	66	6	36537216
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	ZNF131 PER3 MGA ZNF786 ZNF687 MYB ZNF292 ZNF445	1.43e-04	808	66	8	20412781
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ZNF131 FLNB KMT2D ZBTB11 MGA ZNF687	1.44e-04	418	66	6	34709266
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	TNIK ANK3 TRIO MARK3 MINK1 MAP4K4	1.49e-04	421	66	6	36976175
Pubmed	Expression cloning of GABA(B) receptors uncovers similarity to metabotropic glutamate receptors.	GRM4 GRM8	1.58e-04	10	66	2	9069281
Pubmed	The repertoire of olfactory C family G protein-coupled receptors in zebrafish: candidate chemosensory receptors for amino acids.	GRM4 GRM8	1.58e-04	10	66	2	17156446
Pubmed	Cell organization, growth, and neural and cardiac development require αII-spectrin.	ANK2 ANK3	1.58e-04	10	66	2	22159418
Pubmed	Analysis of recently identified osteoporosis susceptibility genes in Han Chinese women.	MARK3 LRP5	1.58e-04	10	66	2	20554715
Pubmed	Meta-analysis of genome-wide association data of bipolar disorder and major depressive disorder.	ANK3 PCLO	1.93e-04	11	66	2	20351715
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNB RRP12 MIB1 DOCK10 RPS16 IDH3B MGA CREBBP RPL11 PRKRA	2.23e-04	1353	66	10	29467282
Pubmed	Identification of E-box factor TFE3 as a functional partner for the E2F3 transcription factor.	MGA CREBBP	2.31e-04	12	66	2	12748276
Pubmed	Activator-mediated recruitment of the MLL2 methyltransferase complex to the beta-globin locus.	KMT2D CREBBP	2.31e-04	12	66	2	17707229
Pubmed	The Hippo pathway kinases LATS1 and LATS2 attenuate cellular responses to heavy metals through phosphorylating MTF1.	MINK1 MAP4K4	2.31e-04	12	66	2	35027733
Interaction	TNIK interactions	TNIK ANK2 ANK3 TRIO CAMKV KALRN MINK1 MGA MAP4K4	3.09e-06	381	64	9	int:TNIK
Interaction	MYB interactions	ZNF131 KMT2D MGA CREBBP MYB ZNF292	4.04e-06	133	64	6	int:MYB
Interaction	AGAP2 interactions	TNIK ANK2 ANK3 TRIO KALRN PCLO MINK1	4.53e-06	210	64	7	int:AGAP2
Interaction	EPB41L4A interactions	CDC42BPA ANK3 MARK3 MINK1 MIB1 MAP4K4	5.43e-06	140	64	6	int:EPB41L4A
Interaction	HLF interactions	PER3 CREBBP MYB	8.54e-06	13	64	3	int:HLF
Interaction	ANK3 interactions	TNIK FLNB ANK2 ANK3 RET USP15	4.23e-05	201	64	6	int:ANK3
Interaction	C11orf52 interactions	TNIK CDC42BPA ANK3 TRIO MARK3 MINK1 MAP4K4	5.70e-05	311	64	7	int:C11orf52
Interaction	CNKSR2 interactions	TNIK KALRN MINK1 GRM4	5.75e-05	66	64	4	int:CNKSR2
Interaction	EPHB2 interactions	TNIK ANK2 ANK3 KALRN MARK3 MAP4K4	6.32e-05	216	64	6	int:EPHB2
Interaction	SLC9A8 interactions	ZNF182 MINK1 MAP4K4	6.68e-05	25	64	3	int:SLC9A8
Interaction	CTNNB1 interactions	LSM12 TNIK KMT2D ANK2 ANK3 LRP5 RPS16 RET IDH3B USP15 CREBBP RPL11	6.84e-05	1009	64	12	int:CTNNB1
Interaction	CDH2 interactions	TNIK LRP5 RPS16 RET CREBBP	7.99e-05	139	64	5	int:CDH2
Interaction	CTTNBP2NL interactions	TNIK MINK1 USP15 MAP4K4	8.09e-05	72	64	4	int:CTTNBP2NL
Interaction	GJA1 interactions	TNIK CDC42BPA ANK3 TRIO KALRN MARK3 MINK1 MIB1 MAP4K4	8.90e-05	583	64	9	int:GJA1
Interaction	KCTD13 interactions	FLNB ANK2 ANK3 TRIO CAMKV KALRN MARK3 PCLO MINK1 RPS16 IDH3B TF RPL11 PRKRA	9.73e-05	1394	64	14	int:KCTD13
Interaction	RAC1 interactions	TNIK FLNB CDC42BPA ANK3 FAM13A TRIO KALRN MARK3 CXCR4 MINK1 LRP5 MAP4K4	1.12e-04	1063	64	12	int:RAC1
Interaction	H3C1 interactions	KMT2D ANK2 ANK3 FLYWCH2 RRP12 RET ADAMTS14 MGA CREBBP MYB ZNF292	1.14e-04	901	64	11	int:H3C1
Interaction	E2F3 interactions	KMT2D MIB1 MGA CREBBP	1.16e-04	79	64	4	int:E2F3
Interaction	PRDM15 interactions	MINK1 RPS16 RPL11 PRKRA	1.22e-04	80	64	4	int:PRDM15
Interaction	FLOT1 interactions	CDC42BPA ANK2 ANK3 TRIO MARK3 PCLO MINK1 MAP4K4	1.25e-04	475	64	8	int:FLOT1
Interaction	OCLN interactions	TNIK CDC42BPA ANK2 ANK3 TRIO MARK3 MINK1 MAP4K4	1.77e-04	500	64	8	int:OCLN
Interaction	E2F5 interactions	KMT2D MIB1 CREBBP	2.02e-04	36	64	3	int:E2F5
Interaction	SHISA7 interactions	TNIK KALRN	2.06e-04	7	64	2	int:SHISA7
Interaction	KALRN interactions	TNIK ANK2 TRIO KALRN	2.47e-04	96	64	4	int:KALRN
Interaction	STRIP1 interactions	TNIK MINK1 USP15 MAP4K4	2.57e-04	97	64	4	int:STRIP1
Interaction	ANK2 interactions	TNIK ANK2 ANK3 KALRN	2.67e-04	98	64	4	int:ANK2
Interaction	DLGAP1 interactions	TNIK TRIO KALRN MINK1 MAP4K4	2.68e-04	180	64	5	int:DLGAP1
Cytoband	10q21	ANK3 ADAMTS14	2.41e-04	16	66	2	10q21
Cytoband	4q22.1	FAM13A SPARCL1	6.47e-04	26	66	2	4q22.1
Cytoband	19q13.1	RASGRP4 RPS16	2.88e-03	55	66	2	19q13.1
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS12 ADAMTS19 ADAMTS14	1.36e-05	19	45	3	50
GeneFamily	Glutamate metabotropic receptors\|Protein phosphatase 1 regulatory subunits	GRM4 GRM8	1.68e-04	8	45	2	281
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	MIB1 CREBBP	9.04e-04	18	45	2	91
Coexpression	LIM_MAMMARY_LUMINAL_MATURE_DN	FAM13A P3H2 SPARCL1 MAP4K4 RECK	4.01e-06	94	66	5	M2580
Coexpression	LIM_MAMMARY_LUMINAL_MATURE_DN	FAM13A P3H2 SPARCL1 MAP4K4 RECK	4.22e-06	95	66	5	MM1328
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_DN	FLNB ANK3 ITGA8 IDH3B MAP4K4 ZNF292	1.14e-05	200	66	6	M9657
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	TNIK ANK3 PPP1R15B RRP12 DOCK10 USP15	4.10e-07	192	66	6	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 KALRN DOCK10 ITGA8 SPARCL1 RPL11	4.36e-07	194	66	6	a3e5a15cf6c1361207f661ee15eb634f77daf1cb
ToppCell	T_cells-CCR7+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ANK3 FAM13A CXCR4 PPP1R15B RPS16 RPL11	5.06e-07	199	66	6	467820d6abe3024d9d655b9672c2f9cdc1303db3
ToppCell	IPF-Epithelial-Ionocyte\|IPF / Disease state, Lineage and Cell class	ANK2 P3H2 PCLO SCNN1G RET	4.01e-06	160	66	5	d65d19f4fae60836bfd4303a1bb7de34e9d83e35
ToppCell	IIF-Lymphocyte-T_NK-Treg\|IIF / Disease, Lineage and Cell Type	KALRN CXCR4 RPS16 USP15 RPL11	5.23e-06	169	66	5	aac6ff89e0b3bc1f644e6cc6a696360659b254b5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 KALRN ITGA8 SPARCL1 RET	5.39e-06	170	66	5	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 KALRN ITGA8 SPARCL1 RET	5.39e-06	170	66	5	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM3 KALRN ITGA8 SPARCL1 RET	5.39e-06	170	66	5	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	KALRN P3H2 DOCK10 ITGA8 SPARCL1	5.54e-06	171	66	5	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	FLNB KALRN P3H2 ITGA8 SPARCL1	7.70e-06	183	66	5	818fd886e0188091310825f9145fa53328f2c979
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	FLNB KALRN P3H2 ITGA8 SPARCL1	7.70e-06	183	66	5	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	FLNB KALRN P3H2 DOCK10 ITGA8	8.78e-06	188	66	5	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ANK3 P3H2 PCLO SCNN1G GRM8	9.01e-06	189	66	5	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	FLNB KALRN P3H2 DOCK10 ITGA8	9.01e-06	189	66	5	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	ILEUM-non-inflamed-(7)_Endothelial_cell-(7)_Lymphatics\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANK2 KALRN P3H2 PCLO RET	9.24e-06	190	66	5	9ce301841ce9486701fa28eb2a9929e35d476878
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 TNIK DOCK10 ITGA8 SPARCL1	9.24e-06	190	66	5	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 CAMKV TRPM3 DOCK10 RET	9.97e-06	193	66	5	4f4f430d7e1b65e19ca829f55ca93edeb6c1c85d
ToppCell	T_cells-Central_memory_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	TNIK ANK3 CXCR4 RPS16 RPL11	9.97e-06	193	66	5	725326d7e3604736b607c19f4069c81cb4f2d20c
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 KALRN ITGA8 RPS16 SPARCL1	1.02e-05	194	66	5	8c37bedb23285735ff3828db3889897fada8c95d
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 CAMKV TRPM3 DOCK10 RET	1.05e-05	195	66	5	9fea1ddb68da83ca43dd8006c9e51295b1817f0e
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 TNIK KALRN ITGA8 SPARCL1	1.07e-05	196	66	5	1450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCell	Mild/Remission\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	CXCR4 RPS16 USP15 RPL11 ZNF292	1.07e-05	196	66	5	71603a3b7df40eb3f267345f55e44a812fea7926
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 KALRN DOCK10 ITGA8 SPARCL1	1.10e-05	197	66	5	31a1852911bda38543916585fda34255fd62a134
ToppCell	COVID-19_Severe-CD4+_T_naive\|COVID-19_Severe / Disease condition and Cell class	ANK3 FAM13A RPS16 RPL11 MYB	1.10e-05	197	66	5	ac26672bd2cb3bc9a11206d8da203bafec3931f6
ToppCell	MS-IIF-Lymphocyte-T/NK-Treg\|IIF / Disease, condition lineage and cell class	KALRN CXCR4 RPS16 USP15 RPL11	1.13e-05	198	66	5	7bbf8403ecf9f8e403b04f18d265ece977cc49e7
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ADAMTS12 TNIK KALRN ITGA8 SPARCL1	1.13e-05	198	66	5	17dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 FAM13A TRPM3 PCLO SCNN1G	1.13e-05	198	66	5	6ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-35\|World / Primary Cells by Cluster	ANK2 FAM13A CXCR4 MAP4K4 ZNF292	1.13e-05	198	66	5	de5214a85fe017eb23d4aa8af624464f062ec57e
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal-6\|World / Primary Cells by Cluster	ANK2 ANK3 TRPM3 PCLO RPS16	1.16e-05	199	66	5	1b1bccf4293f11048709d15a3c892c0edf3da3d2
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ADAMTS12 ANK2 ITGA8 SPARCL1 RECK	1.16e-05	199	66	5	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Parietal_and_Temporal\|World / Primary Cells by Cluster	ANK2 ANK3 TRPM3 PCLO RPS16	1.16e-05	199	66	5	4bee94c116c0da5eba951cb4cea7cc9dcdd6e30f
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_\|World / Primary Cells by Cluster	TNIK ANK2 ANK3 CAMKV PCLO	1.16e-05	199	66	5	058373b4ac3cec2108cb24265628ff0a50646e33
ToppCell	Sepsis-ICU-SEP-Lymphocyte-T/NK-CD4+_T_naive\|ICU-SEP / Disease, condition lineage and cell class	ANK3 FAM13A CXCR4 RPS16 RPL11	1.18e-05	200	66	5	134a5e0cc46264b0aef69d4fd59f38fc7c334f69
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	CXCR4 PCLO RPS16 RPL11 ZNF292	1.18e-05	200	66	5	ac0e023dbb383bbc46c5cc525431778be8f7ef46
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 TRPM3 DCAF8L2 SCNN1G	6.74e-05	147	66	4	64fa0753a3a79f492ef8acc6942bf90d379a983f
ToppCell	Control-Epithelial-Ionocyte\|Epithelial / Disease state, Lineage and Cell class	RASGRP4 ANK2 SCNN1G RET	8.27e-05	155	66	4	4b9369b203a4d7071c56d3d8e6b450e9a0121c41
ToppCell	IPF-Epithelial-Ionocyte\|Epithelial / Disease state, Lineage and Cell class	ANK2 P3H2 SCNN1G RET	8.91e-05	158	66	4	67adf625a959444762d32268b3b7441f6f8b3b8c
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ADAMTS12 TRPM3 ITGA8 RECK	9.13e-05	159	66	4	f34f2729a3872fbb2939e76ad35d7e25f71b8f57
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK RET ADAMTS14 RECK	9.13e-05	159	66	4	d2de9391b00b6c47f5fe28a1bad6da2097107ee0
ToppCell	facs-Marrow-Granulocytes-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK RET ADAMTS14 RECK	9.13e-05	159	66	4	da6b7f8039adc19839d6c090a0b3d68fb6445a79
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Mesenchymal-Unfolded_protein_responsible_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	ADAMTS12 TRPM3 ITGA8 RECK	9.13e-05	159	66	4	929ed98f6c2ad14e8d5af5c6f11a5a3d4b388cf7
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	KALRN DOCK10 ITGA8 SPARCL1	9.35e-05	160	66	4	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5_FEZF2_DYRK2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	9.35e-05	160	66	4	e2504c6deba4949a3a716a9ca68755f787bc0ae0
ToppCell	IPF-Epithelial-Ionocyte\|World / Disease state, Lineage and Cell class	ANK2 PCLO SCNN1G RET	9.58e-05	161	66	4	f1cd5c938cdc08ad8995371b72493850a6cf277a
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	KALRN DOCK10 ITGA8 SPARCL1	9.58e-05	161	66	4	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	Control-Epithelial-Ionocyte\|World / Disease state, Lineage and Cell class	WDR5B PCLO SCNN1G RET	9.81e-05	162	66	4	e3b9b46ce2faff7d099502df14bbf51e9f183f8c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 CAMKV TRPM3 SCNN1G	9.81e-05	162	66	4	285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCell	Control-Epithelial-Ionocyte\|Control / Disease state, Lineage and Cell class	WDR5B PCLO SCNN1G RET	1.00e-04	163	66	4	bf09fa39bf3e6b3a776d5e79c30c96df572956a3
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.00e-04	163	66	4	d7057ae155058a13f3d7c3db5c7fbc3bb2b69376
ToppCell	ICU-SEP-Lymphocyte-T_NK-CD4_Naive\|ICU-SEP / Disease, Lineage and Cell Type	ANK3 RPS16 GRM4 RPL11	1.00e-04	163	66	4	415e67aaae7ccd97a003b4b31b27eed94737deca
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.00e-04	163	66	4	55fd4f21c7a8bea031fb6f7f2c8cc1ff42b00d79
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_E\|356C / Donor, Lineage, Cell class and subclass (all cells)	ZNF131 ZNF182 WDR5B KALRN	1.03e-04	164	66	4	d5bb57c321f2973836efc8990449494cc1fb87c7
ToppCell	NS-moderate-d_16-33-Myeloid-Mast_cell\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TNIK RET ADAMTS14 MYB	1.03e-04	164	66	4	35c673380f75cb4bfe080089bc723c4373bcc7a5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Granulocytic-Mast_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TNIK DOCK10 ADAMTS14 MYB	1.03e-04	164	66	4	2c48c6e4eeee845f0563982d0bfa2a176ca5ef61
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 CAMKV TRPM3 SCNN1G	1.03e-04	164	66	4	6fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	ANK2 ANK3 PCLO RET	1.05e-04	165	66	4	9795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	KALRN P3H2 ITGA8 SPARCL1	1.05e-04	165	66	4	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.08e-04	166	66	4	01544c851588f1cde05d6700c3d1167f70a0fbd5
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.08e-04	166	66	4	c22a97353f7eb084f768c13d7767a80b30f05043
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.10e-04	167	66	4	4e613be2b3ba01160b0c0254fce3c4f72220e580
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.10e-04	167	66	4	18ad85751bd892309627eefc357eb28ec5a7c300
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ANK2 CXCR4 SCNN1G RET	1.13e-04	168	66	4	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.13e-04	168	66	4	3e09516e819cf140a6dbf8f85247d3f08aa35bb8
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.13e-04	168	66	4	4a2e08b047f7170ae4b95eac9b2b128e55beee4a
ToppCell	droplet-Skin-nan-18m-Epithelial-keratinocyte_stem_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK2 FAM13A KALRN RET	1.18e-04	170	66	4	10e0912dd0beab5d0bbe2bd49e477b5962687925
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.18e-04	170	66	4	ce2fd2fbbfd152290be0cf8e513f102fdc182b41
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.18e-04	170	66	4	ab5c6a91c371e4df15b0842828dc55039695ab06
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.18e-04	170	66	4	4aa9e597f6550ac8cac3137a98be58e71efd07d6
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.21e-04	171	66	4	0417fa805ca0acb7e9f6a30bc7b6bdbaba77844d
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK2 CXCR4 SPARCL1 RECK	1.26e-04	173	66	4	f9d6e892d66f9b94e4d5beb9f5dec9b606bc868a
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB TUBE1 DKK2 PRKRA	1.26e-04	173	66	4	4968712af1cca8c932abd3323631d7dcaffd4a66
ToppCell	PND28-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANK2 CXCR4 SPARCL1 RECK	1.26e-04	173	66	4	cbd65dd5b01cc959e3ccbc89330ddd0122296ea3
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C_(NP)-Glut_NP_L5/6_FEZF2-Exc_L5-6_FEZF2_MYBPHL\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS12 ITGA8 GRM4 GRM8	1.26e-04	173	66	4	b002b22f9968b5967d29fe0eab4e796d87b355fa
ToppCell	COVID-19-kidney-REN+Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TRPM3 KALRN ITGA8 RET	1.29e-04	174	66	4	8393f0b43c767839c1630bcb952d62b42efc788d
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB CXCR4 SPARCL1 DKK2	1.35e-04	176	66	4	77516048aefbe1f48e825052756df0c310c1c486
ToppCell	droplet-Lung-21m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PEX3 RET MYB ZNF445	1.35e-04	176	66	4	91ad2c34144f72283ca112fd3b3784f2f6259f65
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB CXCR4 SPARCL1 DKK2	1.35e-04	176	66	4	96779273b94345250cf53ba671203345b43d9e00
ToppCell	PCW_05-06-Neuronal-Neuronal_postreplicative-neuro_migrating_neuronal_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CAMKV TRPM3 DOCK10 RET	1.41e-04	178	66	4	38ffbd01230c99f52274424ee6c172381daffc73
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PER3 FLYWCH2 ITGA8 MGA	1.44e-04	179	66	4	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	ILEUM-non-inflamed-(7)_Lymphatics\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	ANK2 KALRN PCLO RET	1.44e-04	179	66	4	99777a8931356d1206b8ab22aaa1b1d5a600b809
ToppCell	moderate-Myeloid-pDC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	FLNB P3H2 RET MYB	1.47e-04	180	66	4	1d8df7df03a71f49d6683554d3c948ce90dda42e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 TRPM3 DOCK10 SCNN1G	1.47e-04	180	66	4	023ec0b080c8a5cd0f36e83c6b17d4be3c01edb5
ToppCell	COVID-19-Epithelial-Ionocytes\|Epithelial / Condition, Lineage and Cell class	ANK2 DOCK10 SCNN1G RET	1.50e-04	181	66	4	4a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCell	droplet-Liver-nan-3m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNIK KALRN ITGA8 SPARCL1	1.50e-04	181	66	4	fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_SCP_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	TNIK CAMKV TRPM3 DOCK10	1.50e-04	181	66	4	fad7ba168f541ac9d04edebc206f191e48bb7e99
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FLNB CXCR4 SPARCL1 DKK2	1.57e-04	183	66	4	3427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell	LV-07._Pericyte\|World / Chamber and Cluster_Paper	ADAMTS12 CDC42BPA KALRN SPARCL1	1.57e-04	183	66	4	273db6a3b00a93ca852498471187b642b5368185
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	FLNB P3H2 PCLO SCNN1G	1.57e-04	183	66	4	6821dca076318115d360ff426eb1218cfe104063
ToppCell	COVID-19_Convalescent-Lymphoid_T/NK-CD8+_T_naive\|COVID-19_Convalescent / Disease group, lineage and cell class	FLNB UMODL1 RPS16 RPL11	1.60e-04	184	66	4	0299cd30a3ea8e861a9d529043c204048ae21d29
ToppCell	remission-CD8+_T_naive\|remission / disease stage, cell group and cell class	FLNB UMODL1 RPS16 RPL11	1.60e-04	184	66	4	fe20fa4457d4a4a75689978275b0afb5f6243faf
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	FLNB UMODL1 RPS16 RPL11	1.63e-04	185	66	4	863a3d44c1f115942d7a2a2b63a92fe5fc768814
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLNB UMODL1 RPS16 RPL11	1.63e-04	185	66	4	27dbfcd40ec832d5cf757331d8af3b5176ae90fb
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK3 FAM13A P3H2 TF	1.63e-04	185	66	4	fefaf227d89f680d6f3e91c4a94e26ab4d0dc6c3
ToppCell	COVID-19_Convalescent-CD8+_T_naive\|COVID-19_Convalescent / Disease condition and Cell class	FLNB UMODL1 RPS16 RPL11	1.63e-04	185	66	4	2f8277a0b58fb0c49fa76ff6dfa6da961da1f9f5
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-cycling_neuroblast\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK2 CAMKV DOCK10 RET	1.63e-04	185	66	4	0149981d3818a6250f32c08456c28e7037c39d91
ToppCell	droplet-Bladder-BLADDER-1m-Hematologic-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRP4 CXCR4 DOCK10 TUBE1	1.63e-04	185	66	4	969248b63d4ce335f223528de756bcddffadbd77
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	FLNB UMODL1 RPS16 RPL11	1.63e-04	185	66	4	1c23891e4d75f99296d1304af7a9d6c3cb28d04c
ToppCell	Mild_COVID-19-Epithelial-AT1/AT2\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	ANK2 P3H2 SCNN1G RET	1.63e-04	185	66	4	c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD8+_T-CD8+_T_naive-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	FLNB UMODL1 RPS16 RPL11	1.63e-04	185	66	4	ca8e921a6b45cd39474b9f86c95e7be023585c5d
ToppCell	E15.5-Epithelial-airway_epithelial_cell\|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ANK3 FAM13A PCLO MYB	1.67e-04	186	66	4	bb2c7af3b1d8478c49a8626dbfd6c92c5e7adc4a
Drug	tegafur	ADAMTS12 ADAMTS19 ADAMTS14 RECK	1.16e-05	49	65	4	CID000005386
Drug	5279552; Down 200; 22uM; MCF7; HT_HG-U133A_EA	CDC42BPA TRIO MINK1 RET IDH3B CREBBP	1.98e-05	195	65	6	843_DN
Drug	Hymecromone [90-33-5]; Up 200; 22.8uM; HL60; HT_HG-U133A	KMT2D CDC42BPA PCLO ITGA8 TAAR5 GRM4	2.10e-05	197	65	6	3045_UP
Drug	Cefotetan [69712-56-7]; Up 200; 7uM; PC3; HT_HG-U133A	CDC42BPA PER3 RRP12 MINK1 SPARCL1 MYB	2.16e-05	198	65	6	3997_UP
Drug	Liothyronine [6893-02-3]; Up 200; 6.2uM; MCF7; HT_HG-U133A	TRIO CAMKV CXCR4 MINK1 ITGA8 MYB	2.16e-05	198	65	6	4947_UP
Drug	1-amino-2-phosphonomethylcyclopropanecarboxylic acid	GRM4 GRM8	2.40e-05	3	65	2	ctd:C523415
Disease	epilepsy (implicated_via_orthology)	TNIK ANK2 TRIO KALRN MINK1 MIB1 GRM8 MAP4K4	2.48e-09	163	64	8	DOID:1826 (implicated_via_orthology)
Disease	monocyte count	FLNB RASGRP4 CDC42BPA KALRN MARK3 CXCR4 RRP12 DOCK10 GON4L GRM4 MAP4K4 MYB PGBD2	4.23e-06	1320	64	13	EFO_0005091
Disease	hair colour measurement	ADAMTS12 TNIK KMT2D CDC42BPA FAM13A MARK3 DOCK10 LRP5 MYB	6.95e-06	615	64	9	EFO_0007822
Disease	RENAL ADYSPLASIA	ITGA8 RET	1.39e-05	3	64	2	C1619700
Disease	granulocyte percentage of myeloid white cells	FLNB MARK3 CXCR4 RRP12 DOCK10 ZNF292	2.56e-05	268	64	6	EFO_0007997
Disease	Congenital absence of kidneys syndrome	ITGA8 RET	4.61e-05	5	64	2	C1609433
Disease	immature platelet count	TRPM3 KALRN DOCK10 MYB	8.47e-05	106	64	4	EFO_0803544
Disease	osteoarthritis, spine, body mass index	PER3 CAMKV	1.29e-04	8	64	2	EFO_0004340, EFO_1000787
Disease	language measurement	ANK3 DCAF8L2 DOCK10 GON4L	2.09e-04	134	64	4	EFO_0007797
Disease	T-cell acute lymphoblastic leukemia (is_implicated_in)	CXCR4 RPL11	2.52e-04	11	64	2	DOID:5603 (is_implicated_in)
Disease	lymphocyte count	TNIK ZNF131 FLNB KALRN UMODL1 MARK3 CXCR4 MINK1 DOCK10 MYB PGBD2	2.84e-04	1464	64	11	EFO_0004587
Disease	neutrophil percentage of leukocytes	CDC42BPA KALRN MARK3 MINK1 MYB ZNF292 PGBD2	3.49e-04	610	64	7	EFO_0007990
Disease	Intellectual Disability	TRIO TRPM3 GON4L ZBTB11 ZNF292 PRKRA	4.17e-04	447	64	6	C3714756
Disease	Lymphoma, Large-Cell, Follicular	KMT2D CREBBP	4.77e-04	15	64	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	KMT2D CREBBP	4.77e-04	15	64	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	KMT2D CREBBP	4.77e-04	15	64	2	C0079758
Disease	Lymphoma, Follicular, Grade 2	KMT2D CREBBP	4.77e-04	15	64	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	KMT2D CREBBP	4.77e-04	15	64	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	KMT2D CREBBP	4.77e-04	15	64	2	C1956130
Disease	Malignant neoplasm of breast	ADAMTS19 FLNB KMT2D PER3 ANK2 KALRN CXCR4 P3H2 FAM217B	4.94e-04	1074	64	9	C0006142
Disease	T-Cell Lymphoma	KMT2D MGA	5.45e-04	16	64	2	C0079772
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	TRIO ZNF292	6.17e-04	17	64	2	DOID:0060307 (is_implicated_in)
Disease	schizophrenia (is_implicated_in)	ANK3 ITGA8 GRM8	6.59e-04	78	64	3	DOID:5419 (is_implicated_in)
Disease	neutrophil count	FLNB CDC42BPA CXCR4 RRP12 RPS16 MAP4K4 CREBBP ZNF786 MYB ZNF292	7.41e-04	1382	64	10	EFO_0004833
Disease	cortical surface area change measurement, age at assessment	USP15 TF	7.73e-04	19	64	2	EFO_0008007, EFO_0021503
Disease	Lymphoma, Follicular	KMT2D CREBBP	8.58e-04	20	64	2	C0024301
Disease	monocyte percentage of leukocytes	CDC42BPA MARK3 CXCR4 RRP12 DOCK10 MYB PGBD2	1.02e-03	731	64	7	EFO_0007989
Disease	Neurodevelopmental Disorders	ANK2 TRIO ZNF292	1.10e-03	93	64	3	C1535926
Disease	Hereditary Paraganglioma-Pheochromocytoma Syndrome	KMT2D RET	1.14e-03	23	64	2	C1708353
Disease	platelet component distribution width	TRPM3 KALRN MARK3 P3H2 DOCK10 USP15 MYB	1.22e-03	755	64	7	EFO_0007984
Disease	Attention deficit hyperactivity disorder	GRM8 ZNF292	1.24e-03	24	64	2	C1263846
Disease	Adenoid Cystic Carcinoma	MGA CREBBP MYB	1.35e-03	100	64	3	C0010606
Disease	Sezary Syndrome	KMT2D CREBBP	1.57e-03	27	64	2	C0036920
Disease	immature platelet fraction	TRPM3 KALRN DOCK10	1.97e-03	114	64	3	EFO_0009187
Disease	osteoporosis (is_implicated_in)	CXCR4 LRP5	2.07e-03	31	64	2	DOID:11476 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
AKACGKEGARAHLKV	UMODL1	771	Q5DID0
GSAARGRVSVHCKKK	CCDC117	56	Q8IWD4
LKILSKGKRGGHSSV	CXCR4	326	P61073
KGSHVKKCTNRERIG	GRM4	381	Q14833
VVQHTKGCKRKTNGG	CREBBP	1801	Q92793
GEVCTKQRKKGSHGL	DKK2	211	Q9UBU2
GTGIRRQTAHCIKKG	ADAMTS12	841	P58397
SHCRTVKGTLGKASK	ADAMTS14	711	Q8WXS8
GRVAKVKGHRSQKHK	C18orf25	166	Q96B23
DLQKSCIVGGKRKSH	RECK	576	O95980
GKSCKIIKGDFNHTR	ADAMTS19	786	Q8TE59
KAGKKCEALAVGRSS	ANK2	1661	Q01484
KGRHVKTGQLAAIKV	MAP4K4	41	O95819
CKGKEGSALSHVRKI	LSM12	151	Q3MHD2
KHLKGPLTRKCVGAS	MGA	2176	Q8IWI9
STKVAGAKRKGVHCV	FLYWCH2	51	Q96CP2
QTRSIHACNKRTGGK	LRP5	256	O75197
KRFKGHRNNTTVKGV	DCAF8L2	461	P0C7V8
RLNGAKGKIDAKVHS	FLNB	2311	O75369
ETKGKGKITAGKHRR	PCLO	1596	Q9Y6V0
SKQTRSAGCRKGKHK	PER3	726	P56645
RHKKKCIFLGTVLGG	PEX3	11	P56589
APASRHAGKVVQKCK	NEK5	286	Q6P3R8
RKKGKAESCGHATVS	FAM217B	351	Q9NTX9
SKRKSHQECTGKIGG	RASGRP4	6	Q8TDF6
GRGRFSIVKKCIHKA	KALRN	2691	O60229
SVIAKHLKGRIGKQC	MYB	116	P10242
PHGVKAVTKGKRCAV	P3H2	651	Q8IVL5
KVHKNTFGCAGERSK	FAM13A	451	O94988
LGSHGKRNSHIKKCT	GRM8	371	O00222
FGATVKAHKGKVVAC	ITGA8	136	P53708
KCHKEKVSGQVGSRS	MIB1	791	Q86YT6
TKKGRGKVTAVHKAN	IDH3B	206	O43837
TGKLHTCKKFQKRDG	CAMKV	46	Q8NCB2
SGKKHGGVAEQCKRR	DOCK10	1986	Q96BY6
IHIGKGKLHATGSKR	GON4L	116	Q3T8J9
KTGVLQGHCVRDKQK	ANK3	3831	Q12955
TIGKGNFAKVKLARH	MARK3	61	P27448
HFKRVLKGLVDKGSA	H1-9P	156	P60008
TGRKRKVGGSIIHKA	SCNN1G	176	P51170
KGRHVKTGQLAAIKV	MINK1	41	Q8N4C8
AGAAKHERKAAKTLG	TAAR5	241	O14804
KKTATAVAHCKRGNG	RPS16	16	P62249
DVLSGGRHTHVKRKK	PPP1R15B	626	Q5SWA1
TKGCQTVTSGKVRHG	CDC42BPA	1311	Q5VT25
KIRKAAQHGVCSVLK	RRP12	251	Q5JTH9
GRGIHSKVKSAKLLE	PGBD2	11	Q6P3X8
KGRHVKTGQLAAIKV	TNIK	41	Q9UKE5
DVRSGKCLKTLKGHS	WDR5B	111	Q86VZ2
KGVVKRSSPKHCQAV	ZBTB11	186	O95625
AGKKAHGRGHTRKSK	ZNF182	621	P17025
DNLKGKKSCHTAVGR	TF	461	P02787
IADKKRRTGCIGAKH	RPL11	141	P62913
GGSISKGKICSLKAR	TUBE1	56	Q9UJT0
KDHASKSRGKICTIG	TRPM3	236	Q9HCF6
FATKCRLEGTKKGHQ	SPARCL1	486	Q14515
SKSKHRGTKHSRCGK	ZNF292	2311	O60281
TEDTCKGQLTGHKKR	USP15	696	Q9Y4E8
TCTGEGTSKKLAKHR	PRKRA	76	O75569
GKVVKATAFHLKGRA	RET	736	P07949
GKGFAKQCKLTEHIR	ZNF786	431	Q8N393
VSGRKESLKHGCGKH	ZNF445	406	P59923
ISHKKRRGVGKASAL	ZNF687	1156	Q8N1G0
GVSKKQRTGKKIHVC	ZNF131	316	P52739
AGVSQSLRHKVAKKG	TRBV7-1	21	A0A0A6YYK4
VRRLSSGKADGHVKK	TRIO	1781	O75962
QIGVHRKSRKALCAK	KMT2D	3531	O14686