Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

RASGRP4 EYS TBC1D9B PCDHA9 ADGRE3 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2 LRP1B TBC1D9 RYR3 ADGRL4

1.52e-077498816GO:0005509
GeneOntologyMolecularFunctionserine-type endopeptidase activity

CTSC CTRB2 CELA1 KLK5 CTRB1 OVCH1 F3 KLKB1

1.95e-06190888GO:0004252
GeneOntologyMolecularFunctionendopeptidase activity

CAPN7 CTSC CTRB2 CELA1 ADAM30 KLK5 CTRB1 OVCH1 F3 KLKB1 CAPN15

2.93e-064308811GO:0004175
GeneOntologyMolecularFunctionserine-type peptidase activity

CTSC CTRB2 CELA1 KLK5 CTRB1 OVCH1 F3 KLKB1

3.68e-06207888GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

CTSC CTRB2 CELA1 KLK5 CTRB1 OVCH1 F3 KLKB1

4.39e-06212888GO:0017171
GeneOntologyMolecularFunctionpeptidase activity

CAPN7 CTSC CTRB2 CELA1 ADAM30 KLK5 CTRB1 OVCH1 F3 KLKB1 CAPN15

1.39e-046548811GO:0008233
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

CHL1 SDK2 PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

8.06e-091878910GO:0007156
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

CHL1 SDK2 PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

9.89e-073138910GO:0098742
GeneOntologyBiologicalProcessactivation of plasma proteins involved in acute inflammatory response

F3 KLKB1

5.51e-053892GO:0002541
DomainCadherin_tail

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

7.29e-1237908PF15974
DomainCadherin_CBD

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

7.29e-1237908IPR031904
DomainCadherin_2

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

8.54e-1065908PF08266
DomainCadherin_N

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

8.54e-1065908IPR013164
DomainCadherin_CS

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

5.41e-08109908IPR020894
DomainCADHERIN_1

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

7.17e-08113908PS00232
DomainCadherin

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

7.17e-08113908PF00028
DomainCADHERIN_2

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

7.69e-08114908PS50268
Domain-

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

7.69e-081149082.60.40.60
DomainCA

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

8.23e-08115908SM00112
DomainCadherin-like

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

8.80e-08116908IPR015919
DomainCadherin

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.01e-07118908IPR002126
DomainTRYPSIN_SER

CTRB2 CELA1 KLK5 CTRB1 OVCH1 KLKB1

4.76e-0690906IPR033116
DomainTRYPSIN_HIS

CTRB2 CELA1 KLK5 CTRB1 OVCH1 KLKB1

1.04e-05103906IPR018114
DomainTRYPSIN_SER

CTRB2 CELA1 KLK5 CTRB1 OVCH1 KLKB1

1.23e-05106906PS00135
DomainTRYPSIN_HIS

CTRB2 CELA1 KLK5 CTRB1 OVCH1 KLKB1

1.29e-05107906PS00134
DomainGAIN_dom_N

ADGRE3 ADGRL2 ADGRL4

1.74e-0511903IPR032471
DomainGAIN

ADGRE3 ADGRL2 ADGRL4

1.74e-0511903PF16489
DomainPeptidase_S1A

CTRB2 CELA1 KLK5 CTRB1 OVCH1 KLKB1

1.77e-05113906IPR001314
DomainTRYPSIN_DOM

CTRB2 CELA1 KLK5 CTRB1 OVCH1 KLKB1

1.95e-05115906PS50240
DomainGPS

ADGRE3 ADGRF5 ADGRL2 ADGRL4

2.09e-0534904SM00303
DomainGPCR_2_secretin-like_CS

ADGRE3 ADGRF5 ADGRL2 ADGRL4

2.09e-0534904IPR017983
DomainTryp_SPc

CTRB2 CELA1 KLK5 CTRB1 OVCH1 KLKB1

2.15e-05117906SM00020
DomainGPS

ADGRE3 ADGRF5 ADGRL2 ADGRL4

2.35e-0535904PF01825
DomainTrypsin

CTRB2 CELA1 KLK5 CTRB1 OVCH1 KLKB1

2.61e-05121906PF00089
DomainTrypsin_dom

CTRB2 CELA1 KLK5 CTRB1 OVCH1 KLKB1

2.61e-05121906IPR001254
DomainGPS

ADGRE3 ADGRF5 ADGRL2 ADGRL4

2.64e-0536904PS50221
DomainPeptidase_S1_PA

CTRB2 CELA1 KLK5 CTRB1 OVCH1 KLKB1

2.86e-05123906IPR009003
DomainGPS

ADGRE3 ADGRF5 ADGRL2 ADGRL4

2.95e-0537904IPR000203
DomainG_PROTEIN_RECEP_F2_2

ADGRE3 ADGRF5 ADGRL2 ADGRL4

9.80e-0550904PS00650
Domain7tm_2

ADGRE3 ADGRF5 ADGRL2 ADGRL4

9.80e-0550904PF00002
DomainGPCR_2_secretin-like

ADGRE3 ADGRF5 ADGRL2 ADGRL4

2.00e-0460904IPR000832
DomainGPCR_2-like

ADGRE3 ADGRF5 ADGRL2 ADGRL4

2.00e-0460904IPR017981
DomainEGF-like_dom

EYS ADGRE3 ADAM30 TECTA LRP1B ADGRL4 SORL1

2.01e-04249907IPR000742
DomainG_PROTEIN_RECEP_F2_4

ADGRE3 ADGRF5 ADGRL2 ADGRL4

2.13e-0461904PS50261
DomainTHIOL_PROTEASE_CYS

CAPN7 CTSC CAPN15

2.60e-0426903PS00139
DomainTHIOL_PROTEASE_ASN

CAPN7 CTSC CAPN15

2.91e-0427903PS00640
DomainTHIOL_PROTEASE_HIS

CAPN7 CTSC CAPN15

2.91e-0427903PS00639
DomainPept_cys_AS

CAPN7 CTSC CAPN15

3.25e-0428903IPR000169
DomainEGF_3

EYS ADGRE3 ADAM30 LRP1B ADGRL4 SORL1

9.61e-04235906PS50026
DomainEGF

EYS ADGRE3 TECTA LRP1B ADGRL4 SORL1

9.61e-04235906SM00181
DomainEGF_Ca-bd_CS

EYS ADGRE3 LRP1B ADGRL4

1.24e-0397904IPR018097
DomainEGF_CA

EYS ADGRE3 LRP1B ADGRL4

1.34e-0399904PS01187
DomainASX_HYDROXYL

EYS ADGRE3 LRP1B ADGRL4

1.39e-03100904PS00010
DomainWD40

WDR36 DNAI2 CDC20B WDR55 WDR89 HERC1

1.58e-03259906PF00400
DomainEGF-type_Asp/Asn_hydroxyl_site

EYS ADGRE3 LRP1B ADGRL4

1.72e-03106904IPR000152
DomainWD40

WDR36 DNAI2 CDC20B WDR55 WDR89 HERC1

1.88e-03268906SM00320
DomainCalpain_cysteine_protease

CAPN7 CAPN15

2.01e-0314902IPR022684
DomainLdl_recept_b

LRP1B SORL1

2.01e-0314902PF00058
DomainLDLRB

LRP1B SORL1

2.01e-0314902PS51120
DomainWD40_repeat

WDR36 DNAI2 CDC20B WDR55 WDR89 HERC1

2.02e-03272906IPR001680
DomainWD_REPEATS_1

WDR36 DNAI2 CDC20B WDR55 WDR89 HERC1

2.26e-03278906PS00678
DomainIg_I-set

CHL1 SDK2 CD22 UNC5C ADGRF5

2.26e-03190905IPR013098
DomainI-set

CHL1 SDK2 CD22 UNC5C ADGRF5

2.26e-03190905PF07679
DomainWD_REPEATS_2

WDR36 DNAI2 CDC20B WDR55 WDR89 HERC1

2.30e-03279906PS50082
DomainWD_REPEATS_REGION

WDR36 DNAI2 CDC20B WDR55 WDR89 HERC1

2.30e-03279906PS50294
DomainCysPc

CAPN7 CAPN15

2.31e-0315902SM00230
DomainPeptidase_C2_calpain_cat

CAPN7 CAPN15

2.31e-0315902IPR001300
DomainPeptidase_C2

CAPN7 CAPN15

2.31e-0315902PF00648
DomainCALPAIN_CAT

CAPN7 CAPN15

2.31e-0315902PS50203
DomainLY

LRP1B SORL1

2.31e-0315902SM00135
DomainLDLR_classB_rpt

LRP1B SORL1

2.31e-0315902IPR000033
DomainGRAM

TBC1D9B TBC1D9

2.64e-0316902SM00568
DomainEGF_CA

EYS ADGRE3 LRP1B ADGRL4

2.87e-03122904SM00179
DomainEGF-like_Ca-bd_dom

EYS ADGRE3 LRP1B ADGRL4

3.05e-03124904IPR001881
DomainWD40_repeat_dom

WDR36 DNAI2 CDC20B WDR55 WDR89 HERC1

3.13e-03297906IPR017986
DomainFN3_dom

CHL1 SDK2 IL31RA F3 SORL1

3.41e-03209905IPR003961
DomainApc4_WD40_dom

WDR36 WDR55

4.12e-0320902IPR024977
DomainANAPC4_WD40

WDR36 WDR55

4.12e-0320902PF12894
DomainDAG/PE-bd

RASGRP4 PRKCD

4.54e-0321902IPR020454
Domain-

CHL1 SDK2 IL31RA CD22 UNC5C ADGRF5 F3 CD200R1 SORL1

4.63e-036639092.60.40.10
Pubmed

Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.02e-171591815640798
Pubmed

Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

3.82e-171791829911975
Pubmed

CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

6.86e-171891815570159
Pubmed

Genomic organization of the family of CNR cadherin genes in mice and humans.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

6.86e-171891810662547
Pubmed

Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.14e-152491824698270
Pubmed

Interaction with protocadherin-gamma regulates the cell surface expression of protocadherin-alpha.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

4.77e-152891815347688
Pubmed

Diversity revealed by a novel family of cadherins expressed in neurons at a synaptic complex.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4

1.24e-13119169655502
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

2.39e-125791832633719
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

2.76e-125891830377227
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.04e-116891811230163
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.67e-117291810380929
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

2.10e-117491810817752
Pubmed

The DNA sequence and comparative analysis of human chromosome 5.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

2.34e-117591815372022
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

2.91e-117791810835267
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

3.99e-118091810716726
Pubmed

Proteins of the CNR family are multiple receptors for Reelin.

PCDHA9 PCDHA13 PCDHA8 PCDHA6 PCDHA4

8.56e-111291510612399
Pubmed

A Genome-Wide CRISPR Screen Identifies Genes Critical for Resistance to FLT3 Inhibitor AC220.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

9.93e-1011991828625976
Pubmed

Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women.

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

4.46e-0819391822589738
Pubmed

Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse.

CTRB2 CELA1 CTRB1

1.73e-0759136589791
Pubmed

The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.

ADGRE3 ADGRF5 ADGRL2 ADGRL4

9.91e-072991415203201
Pubmed

International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.

ADGRE3 ADGRF5 ADGRL2 ADGRL4

1.69e-063391425713288
Pubmed

Identification of transcripts with enriched expression in the developing and adult pancreas.

RPL37A UGT2B10 CTRB2 CELA1 REG1A CTRB1 LARS2 CHRNA1 ADGRL4 CFHR4

5.61e-06624911018554416
Pubmed

Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.

CTRB2 CTRB1

6.77e-06291230076839
Pubmed

The CTRB1-CTRB2 risk allele for chronic pancreatitis discovered in European populations does not contribute to disease risk variation in the Chinese population due to near allele fixation.

CTRB2 CTRB1

6.77e-06291228951524
Pubmed

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.

CTRB2 CTRB1

6.77e-06291228754779
Pubmed

Sequencing of the complex CTRB1-CTRB2 locus in chronic pancreatitis.

CTRB2 CTRB1

6.77e-06291233036922
Pubmed

Evolutionary relationships between laboratory mice and subspecies of Mus musculus based on the restriction fragment length variants of the chymotrypsin gene at the Prt-2 locus.

CTRB2 CTRB1

6.77e-0629122565717
Pubmed

Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA.

CTRB2 CTRB1

6.77e-0629122917002
Pubmed

Intron-less processed Pcdhalpha genes in the central nervous system.

PCDHA8 PCDHA6

6.77e-06291214697259
Pubmed

Genomic cloning and partial characterization of human chymotrypsinogen gene.

CTRB2 CTRB1

6.77e-0629128186414
Pubmed

Activation of PKCdelta and ERK1/2 in the sensitivity to UV-induced apoptosis of human cells harboring 4977 bp deletion of mitochondrial DNA.

PRKCD MAPK1

6.77e-06291219477272
Pubmed

Activation of protein kinase C delta by ψδRACK peptide promotes embryonic stem cell proliferation through ERK 1/2.

PRKCD MAPK1

2.03e-05391224332066
Pubmed

Identification of two novel PCDHA9 mutations associated with Hirschsprung's disease.

PCDHA9 PCDHA12

2.03e-05391229477871
Pubmed

Genetic study of pancreatic proteinase in mice (Mus musculus): linkage of the Prt-2 locus on chromosome 8.

CTRB2 CTRB1

2.03e-0539121016231
Pubmed

Secretagogue-induced pancreatitis in mice devoid of chymotrypsin.

CTRB2 CTRB1

2.03e-05391238981616
Pubmed

Oxidative stress-induced apoptosis is mediated by ERK1/2 phosphorylation.

PRKCD MAPK1

2.03e-05391214597424
Pubmed

Genetic study of pancreatic proteinase in mice (Mus musculus): genetic variants of trypsin and chymotrypsin.

CTRB2 CTRB1

2.03e-0539121008801
Pubmed

Active plasma kallikrein localizes to mast cells and regulates epithelial cell apoptosis, adipocyte differentiation, and stromal remodeling during mammary gland involution.

CTSC KLKB1

2.03e-05391219297327
Pubmed

Accumulation of tissue factor in endothelial cells induces cell apoptosis, mediated through p38 and p53 activation.

MAPK1 F3

2.03e-05391225903973
Pubmed

Protein kinase Cdelta supports survival of MDA-MB-231 breast cancer cells by suppressing the ERK1/2 pathway.

PRKCD MAPK1

2.03e-05391219833733
Pubmed

SORLA/SORL1 functionally interacts with SPAK to control renal activation of Na(+)-K(+)-Cl(-) cotransporter 2.

SLC12A1 SORL1

2.03e-05391220385770
Pubmed

Evolutionary expansion of polyaspartate motif in the activation peptide of mouse cationic trypsinogen limits autoactivation and protects against pancreatitis.

CTRB2 CTRB1

2.03e-05391234643096
Pubmed

Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice.

CTRB2 CTRB1

2.03e-05391232678161
Pubmed

Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.

PCDHA9 MED14 PCDHA12 PCDHA8 PCDHA6 PCDHA3 PCDHA2

2.61e-0532991717474147
Pubmed

Leukotactin-1-induced ERK activation is mediated via Gi/Go protein/PLC/PKC delta/Ras cascades in HOS cells.

PRKCD MAPK1

4.05e-05491212759139
Pubmed

Induction of tissue factor expression in human monocytic cells by protease inhibitors through activating activator protein-1 (AP-1) with phosphorylation of Jun-N-terminal kinase and p38.

MAPK1 F3

4.05e-05491215041276
Pubmed

Induction of endothelial cell proliferation by recombinant and microparticle-tissue factor involves beta1-integrin and extracellular signal regulated kinase activation.

MAPK1 F3

4.05e-05491220616308
Pubmed

Phosphorylation of protein kinase Cdelta on distinct tyrosine residues induces sustained activation of Erk1/2 via down-regulation of MKP-1: role in the apoptotic effect of etoposide.

PRKCD MAPK1

4.05e-05491218434324
Pubmed

PKCδ-dependent activation of ERK1/2 leads to upregulation of the human NHE2 transcriptional activity in intestinal epithelial cell line C2BBe1.

PRKCD MAPK1

4.05e-05491222052014
Pubmed

Glycogen synthase kinase-3 is a negative regulator of extracellular signal-regulated kinase.

PRKCD MAPK1

4.05e-05491216278684
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

CHL1 VNN2 UGT2B10 ADGRF5 KLKB1 ADGRL4

6.06e-0525791616335952
Pubmed

Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.

CHL1 TRPS1 MIB1 SORL1

6.56e-058291431073041
Pubmed

Sulfated polymannuroguluronate, a novel anti-acquired immune deficiency syndrome drug candidate, decreased vulnerability of PC12 cells to human immunodeficiency virus tat protein through attenuating calcium overload.

PRKCD MAPK1

6.74e-05591218092356
Pubmed

Genetic study of pancreatic proteinase and alpha-amylase in mice (Mus musculus).

CTRB2 CTRB1

6.74e-0559124461036
Pubmed

Functional role of extracellular signal-regulated kinase activation and c-Jun induction in phorbol ester-induced promoter activation of human 12(S)-lipoxygenase gene.

PRKCD MAPK1

6.74e-05591211914583
Pubmed

Formation of ternary complex of human biliverdin reductase-protein kinase Cδ-ERK2 protein is essential for ERK2-mediated activation of Elk1 protein, nuclear factor-κB, and inducible nitric-oxidase synthase (iNOS).

PRKCD MAPK1

6.74e-05591222065579
Pubmed

CRP regulates the expression and activity of tissue factor as well as tissue factor pathway inhibitor via NF-kappaB and ERK 1/2 MAPK pathway.

MAPK1 F3

6.74e-05591219631649
Pubmed

Activation and nuclear translocation of PKCdelta, Pyk2 and ERK1/2 by gonadotropin releasing hormone in HEK293 cells.

PRKCD MAPK1

6.74e-05591212943720
Pubmed

Factor Xa induces tissue factor expression in endothelial cells by P44/42 MAPK and NF-κB-dependent pathways.

MAPK1 F3

6.74e-05591220451919
Pubmed

High level of cannabinoid receptor 1, absence of regulator of G protein signalling 13 and differential expression of Cyclin D1 in mantle cell lymphoma.

TBC1D9 SORL1

6.74e-05591212970790
Pubmed

Genetic and biochemical characterization of a new chymotrypsin isozyme of the house mouse, CTRA-1.

CTRB2 CTRB1

6.74e-0559121820020
Pubmed

CHL1 negatively regulates the proliferation and neuronal differentiation of neural progenitor cells through activation of the ERK1/2 MAPK pathway.

CHL1 MAPK1

6.74e-05591220933598
Pubmed

Protein kinase C δ (PKCδ)-extracellular signal-regulated kinase 1/2 (ERK1/2) signaling cascade regulates glycogen synthase kinase-3 (GSK-3) inhibition-mediated interleukin-10 (IL-10) expression in lipopolysaccharide (LPS)-induced endotoxemia.

PRKCD MAPK1

6.74e-05591222393041
Pubmed

Common deletion variants causing protocadherin-α deficiency contribute to the complex genetics of BAV and left-sided congenital heart disease.

PCDHA9 PCDHA12

6.74e-05591234888534
Pubmed

NEDD4 controls the expression of GUCD1, a protein upregulated in proliferating liver cells.

PCDHA8 PCDHA6

1.01e-04691224743017
Pubmed

Protein kinase C delta associates with and phosphorylates Stat3 in an interleukin-6-dependent manner.

PRKCD MAPK1

1.01e-04691210446219
Pubmed

Different regulation of PKC isoenzymes and MAPK by PSK and IL-2 in the proliferative and cytotoxic activities of the NKL human natural killer cell line.

PRKCD MAPK1

1.01e-04691212536241
Pubmed

C-peptide increases Na,K-ATPase expression via PKC- and MAP kinase-dependent activation of transcription factor ZEB in human renal tubular cells.

PRKCD MAPK1

1.01e-04691222162761
Pubmed

Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.

CTRB2 CTRB1

1.01e-04691223814066
Pubmed

STAT3 serine phosphorylation by ERK-dependent and -independent pathways negatively modulates its tyrosine phosphorylation.

PRKCD MAPK1

1.01e-0469129343414
Pubmed

The EGF-TM7 family: a postgenomic view.

ADGRE3 ADGRL4

1.01e-04691214647991
Pubmed

Repression of Stat3 activity by activation of mitogen-activated protein kinase (MAPK).

PRKCD MAPK1

1.01e-0469129872331
Pubmed

Juxtaposition of CNR protocadherins and reelin expression in the developing spinal cord.

PCDHA8 PCDHA6

1.01e-04691211312598
Pubmed

Involvement of ERK1/2/NF-κB signal transduction pathway in TF/FVIIa/PAR2-induced proliferation and migration of colon cancer cell SW620.

MAPK1 F3

1.01e-04691221625939
Pubmed

Serine phosphorylation and negative regulation of Stat3 by JNK.

PRKCD MAPK1

1.01e-04691210521505
Pubmed

Reduced thrombosis in Klkb1-/- mice is mediated by increased Mas receptor, prostacyclin, Sirt1, and KLF4 and decreased tissue factor.

F3 KLKB1

1.01e-04691225339356
Pubmed

Developmental vascular remodeling defects and postnatal kidney failure in mice lacking Gpr116 (Adgrf5) and Eltd1 (Adgrl4).

ADGRF5 ADGRL4

1.01e-04691228806758
Pubmed

Abstracts of meeting presentations: Human gene mapping 7, Los Angeles Conference (1983), Seventh International Workshop on Human Gene Mapping.

CTRB2 CELA1 CTRB1

1.16e-04369136690234
Pubmed

Tissue factor/activated factor VIIa induces matrix metalloproteinase-7 expression through activation of c-Fos via ERK1/2 and p38 MAPK signaling pathways in human colon cancer cell.

MAPK1 F3

1.41e-04791222076613
Pubmed

Histamine induces Egr-1 expression in human aortic endothelial cells via the H1 receptor-mediated protein kinase Cdelta-dependent ERK activation pathway.

PRKCD MAPK1

1.41e-04791218682391
Pubmed

Erythropoietin-induced serine 727 phosphorylation of STAT3 in erythroid cells is mediated by a MEK-, ERK-, and MSK1-dependent pathway.

PRKCD MAPK1

1.41e-04791212763138
Pubmed

Phosphorylation sites on tau identified by nanoelectrospray mass spectrometry: differences in vitro between the mitogen-activated protein kinases ERK2, c-Jun N-terminal kinase and P38, and glycogen synthase kinase-3beta.

PRKCD MAPK1

1.41e-04791210737616
Pubmed

NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation.

CTRB2 CELA1 CTRB1

1.85e-044291337353485
Pubmed

CKbeta8/CCL23 and its isoform CKbeta8-1 induce up-regulation of cyclins via the G(i)/G(o) protein/PLC/PKCdelta/ERK leading to cell-cycle progression.

PRKCD MAPK1

1.88e-04891220097574
Pubmed

Neuromuscular synaptic patterning requires the function of skeletal muscle dihydropyridine receptors.

CHRNA1 RYR3

1.88e-04891221441923
Pubmed

Activation of Raf-1 signaling by protein kinase C through a mechanism involving Raf kinase inhibitory protein.

PRKCD MAPK1

1.88e-04891212551925
Pubmed

HIV-1 Tat protein induces TNF-alpha and IL-10 production by human macrophages: differential implication of PKC-betaII and -delta isozymes and MAP kinases ERK1/2 and p38.

PRKCD MAPK1

2.41e-04991218692180
Pubmed

Phosphorylation of p62 by cdk1 controls the timely transit of cells through mitosis and tumor cell proliferation.

PRKCD MAPK1

2.41e-04991220974803
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

EYS LHFPL4 TRPS1 CTRB2 ADGRL2 LARS2

2.44e-0433291637433992
Pubmed

Rat gene mapping using PCR-analyzed microsatellites.

CTRB2 CELA1 CTRB1

2.75e-04489131628813
Pubmed

Tau is phosphorylated by GSK-3 at several sites found in Alzheimer disease and its biological activity markedly inhibited only after it is prephosphorylated by A-kinase.

PRKCD MAPK1

3.67e-04119129771888
Pubmed

Genome-wide association study of a heart failure related metabolomic profile among African Americans in the Atherosclerosis Risk in Communities (ARIC) study.

EYS SLC12A1 ADGRL2

4.34e-045691323934736
Pubmed

Tissue microarray analysis of signal transducers and activators of transcription 3 (Stat3) and phospho-Stat3 (Tyr705) in node-negative breast cancer shows nuclear localization is associated with a better prognosis.

PRKCD MAPK1

4.39e-041291212576423
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

JPH2 RYR3

4.39e-041291219095005
Pubmed

Involvement of aberrant glycosylation in phosphorylation of tau by cdk5 and GSK-3beta.

PRKCD MAPK1

4.39e-041291212387894
Pubmed

New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry.

PRKCD MAPK1

4.39e-04129129832145
Pubmed

Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.

MKRN4P RPL37A WDR36 ELAPOR1 CELA1 KLC4

4.40e-0437191615747579
Pubmed

Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes.

PCDHA12 PCDHA8 PCDHA6

5.07e-045991323754746
Pubmed

HIV Nef, paxillin, and Pak1/2 regulate activation and secretion of TACE/ADAM10 proteases.

PRKCD MAPK1

5.18e-041391223317503
Pubmed

Constitutively active Galpha16 stimulates STAT3 via a c-Src/JAK- and ERK-dependent mechanism.

PRKCD MAPK1

5.18e-041391214551213
InteractionPCDHA10 interactions

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

2.90e-1422888int:PCDHA10
InteractionPCDHA7 interactions

PCDHA9 PCDHA12 PCDHA8 PCDHA4 PCDHA2

2.75e-0914885int:PCDHA7
InteractionPCDHA8 interactions

PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

4.07e-0955887int:PCDHA8
InteractionPCDHGA10 interactions

PCDHA9 PCDHA12 PCDHA8 PCDHA4

1.25e-0619884int:PCDHGA10
InteractionPCDHA11 interactions

PCDHA9 PCDHA12 PCDHA4 PCDHA3

1.25e-0619884int:PCDHA11
InteractionPCDHA6 interactions

PCDHA8 PCDHA6 PCDHA3

6.63e-069883int:PCDHA6
InteractionPCDHA1 interactions

PCDHA8 PCDHA4 PCDHA3

6.63e-069883int:PCDHA1
InteractionLONP2 interactions

PCDHA9 PCDHA12 PCDHA8 PCDHA4 PCDHA3

7.53e-0662885int:LONP2
InteractionPCDHA3 interactions

PCDHA9 PCDHA8 PCDHA6 PCDHA3

1.42e-0534884int:PCDHA3
InteractionZNF563 interactions

HERC1 LRP1B SORL1

1.72e-0512883int:ZNF563
InteractionCTRB2 interactions

CTRB2 CTRB1

5.64e-053882int:CTRB2
InteractionFLT3 interactions

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

7.57e-05318888int:FLT3
Cytoband5q31

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

8.65e-111159185q31
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHA9 WDR55 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

8.92e-09298919chr5q31
Cytoband18q12

NOL4 MOCOS

2.99e-041391218q12
Cytoband16q23.1

CTRB2 CTRB1

1.85e-033291216q23.1
GeneFamilyClustered protocadherins

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.25e-106470820
GeneFamilyAdhesion G protein-coupled receptors, subfamily L

ADGRL2 ADGRL4

8.82e-054702918
GeneFamilyWD repeat domain containing

WDR36 DNAI2 CDC20B WDR55 WDR89 HERC1

5.28e-04262706362
GeneFamilyWD repeat domain containing|GRAM domain containing|BEACH domain containing

TBC1D9B TBC1D9

1.12e-03137021146
GeneFamilyC2 domain containing|Calpains

CAPN7 CAPN15

1.50e-0315702975
GeneFamilyKallikreins

KLK5 KLKB1

1.71e-0316702616
GeneFamilyFibronectin type III domain containing

CHL1 SDK2 IL31RA SORL1

3.44e-03160704555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

CHL1 SDK2 UNC5C ADGRF5

3.52e-03161704593
GeneFamilyEF-hand domain containing

RASGRP4 TBC1D9B TBC1D9 RYR3

1.03e-02219704863
GeneFamilyOlfactory receptors, family 1

OR1S1 OR1S2

1.05e-0240702147
GeneFamilyC2-set domain containing|Immunoglobulin like domain containing|Scavenger receptors

CD22 CD200R1

1.05e-0240702592
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

3.33e-06261908MM1277
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

PCDHA9 PCDHA13 PCDHA12 PCDHA6 PCDHA4 PCDHA3 PCDHA2

1.84e-05238907M2020
CoexpressionTABULA_MURIS_SENIS_PANCREAS_LEUKOCYTE_AGEING

CTRB2 CELA1 REG1A CTRB1

2.65e-0550904MM3814
CoexpressionGAUCHER_PBMC_YF_VAX_STAMARIL_UNKNOWN_AGE_3DY_DN

RPL37A VNN2 ADGRE3 ELAPOR1 SORL1

3.00e-05104905M41147
CoexpressionGAUCHER_PBMC_YF_VAX_STAMARIL_UNKNOWN_AGE_10DY_DN

RPL37A VNN2 ADGRE3 ELAPOR1 SORL1

3.29e-05106905M41161
CoexpressionGSE22611_MUTANT_NOD2_VS_CTRL_TRANSDUCED_HEK293T_CELL_DN

UNC5C MED14 MAGEC3 ADGRF5 LRP1B ADGRL4

5.99e-05196906M8171
CoexpressionAtlasDevelopingLowerUrinaryTract_P1_ureter_emap-30363_top-relative-expression-ranked_1000

SLC12A1 TRPS1 MIB1 MED14 UGT2B10 CELA1 JPH2 ADGRF5 F3 ZFPM2 RYR3 ADGRL4 SORL1

1.54e-057748713gudmap_developingLowerUrinaryTract_P1_ureter_1000
ToppCell368C-Endothelial_cells-Endothelial-E|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

LHFPL4 ZNF556 ADGRE3 CDC20B ADGRF5 ADGRL2

8.25e-071569164877aabf647238c0279e497345b6a6d5ee07ef9c
ToppCell368C-Endothelial_cells-Endothelial-E-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

LHFPL4 ZNF556 ADGRE3 CDC20B ADGRF5 ADGRL2

8.25e-071569161d681fa17e62815f5d5f90c86be3c248b38e011b
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR89 LARS2 LRP1B KLKB1 UNC79 RYR3

1.32e-0616991612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

CHL1 ADGRF5 ADGRL2 LRP1B ZFPM2 ADGRL4

3.10e-061969164ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Interneuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

CHL1 GPR85 UNC5C PCDHA3 LRP1B UNC79

3.48e-06200916a6500d0d2e8bcac92381ab771dbdee66b0e1d48e
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Cadm2_(Cadm2+_state)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IL31RA PCDHA6 PCDHA3 TAFA4

6.54e-0659914b2c10c4c0a750d7f49f5a813ab5d103fb07ca76b
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Cadm2_(Cadm2+_state)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IL31RA PCDHA6 PCDHA3 TAFA4

6.54e-0659914bcac768e1e034e27bab7cad3c2bf09a8f0a819ad
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Cadm2_(Cadm2+_state)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

IL31RA PCDHA6 PCDHA3 TAFA4

6.54e-0659914f9b9464f4d786991aad01b47e2a8fd33f889c2e2
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

NOL4 EYS KLK5 TAFA4 LRP1B

9.84e-06139915a1945b07f177cde40e7eea03a19236ce76165857
ToppCelldroplet-Lung-nan-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 METRNL CTSC PRKCD OAS3

1.25e-05146915ed932d43e9efd064ee4b49ddef529f3d041be765
ToppCelldroplet-Lung-nan-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 METRNL CTSC PRKCD OAS3

1.25e-051469150d74962779055c774312d59fc3b1365163741c3a
ToppCelldroplet-Pancreas-Exocrine-18m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 METRNL CTSC OAS3 CD200R1

1.29e-05147915684e2d8d2f0516cf8b0dc53efa7efc3050bbf0d1
ToppCelldroplet-Pancreas-Exocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 METRNL CTSC OAS3 CD200R1

1.29e-05147915c031fad0a4e192019775809968e46da54a111d27
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC12A1 UNC5C TECTA LRP1B RYR3

1.94e-05160915c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC12A1 UNC5C TECTA LRP1B RYR3

1.94e-0516091525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellfacs-Brain_Myeloid-Cerebellum_|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 CD22 CTSC TRPS1 LARS2

2.00e-051619155c762609531a7c5505aa5637abf8e0311568d7fd
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 CD22 CTSC TRPS1 LARS2

2.00e-05161915b14a83ad07a7acb07c766aa862b527698976b6fc
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 CD22 CTSC TRPS1 LARS2

2.00e-05161915c5d9d47dcedfbb1ac77f4afaf860ae4d9f26fd3f
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 CD22 CTSC TRPS1 LARS2

2.00e-0516191526c0d876339bfd34d9a43af5b9fb08f50526f2c9
ToppCellfacs-MAT-Fat-3m-Myeloid-nan|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 CTSC PRKCD TBC1D9 CD200R1

2.19e-051649151250876abd7311f86730e5b9c03c3610cc2ff6d3
ToppCellfacs-MAT-Fat-3m-Myeloid|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 CTSC PRKCD TBC1D9 CD200R1

2.19e-05164915fa0d77b648cde5e42b9394e877168c80de238bde
ToppCellfacs-Lung-nan-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

METRNL PRKCD OAS3 LARS2 SORL1

2.25e-05165915720649f330382ea2a68c64a5344160a048afb8f1
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 METRNL CTSC PRKCD OAS3

2.38e-05167915d62d5dec30d006a9cc8f3bc5ccc578e10f105027
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CHL1 SDK2 CDC20B PCDHA12 PCDHA2

2.38e-0516791517c653b46507c8bb85da95836ae72a6015336142
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 METRNL CTSC PRKCD OAS3

2.45e-051689153d8c431a3c8899383212fe6a7627889c40c5f3ef
ToppCellPND07-28-samps-Myeloid|PND07-28-samps / Age Group, Lineage, Cell class and subclass

METRNL CTSC PRKCD TBC1D9 CD200R1

2.45e-0516891587512f9e5e95333e7ffc6efa1e93bab2ba9154c6
ToppCellfacs-Lung-nan-3m-Myeloid-Classical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

METRNL CTSC PRKCD OAS3 LARS2

2.52e-0516991505b138511039f1255a5f647040b1b9bdf222bd52
ToppCellfacs-Lung-nan-3m-Myeloid-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

METRNL CTSC PRKCD OAS3 LARS2

2.52e-05169915bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCellfacs-BAT-Fat-18m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

METRNL CTSC TRPS1 PRKCD TBC1D9

2.75e-0517291536fe66a8c0aecee7a19269be23210c0ed7abb155
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5C KLK5 F3 ZFPM2 RYR3

2.75e-051729156c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR89 LARS2 LRP1B UNC79 RYR3

2.82e-0517391566f37c1437705734b20601656fa4aa1d92ca30be
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR89 LARS2 LRP1B UNC79 RYR3

2.82e-05173915649b08a409095592cccf31883be69c754411280d
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Neutrophil|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RASGRP4 VNN2 ADGRE3 ELAPOR1 TECTA

3.07e-05176915676839d07450b313222622e0ffd305c732cbad6d
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 GPR85 ADGRF5 STARD6 ADGRL4

3.07e-0517691527e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SDK2 CAPN7 CELA1 HERC1 CTRB1

3.24e-05178915fcbbcc44271515de1969b4732b6441c012693d5f
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

UNC5C KLK5 F3 ZFPM2 RYR3

3.32e-051799157394e77e665bf16d3733df91bb12907be460ab44
ToppCellfacs-Spleen-nan-3m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A CD22 PRKCD LARS2 SORL1

4.09e-051879153ca3954f45f167e98a230f2847f0582d74fcd32e
ToppCellControl-Endothelial-VE_Capillary_A|Control / Disease state, Lineage and Cell class

CHL1 ADGRF5 ADGRL2 ZFPM2 ADGRL4

4.09e-0518791554d7588172ac145ff5045ad9771636729ca3f0ca
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CHL1 ADGRF5 ADGRL2 ZFPM2 ADGRL4

4.41e-051909150e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CHL1 ADGRF5 ADGRL2 ZFPM2 ADGRL4

4.41e-051909150a351609a72fd638c84b2435782e312ee6a33aac
ToppCellfacs-Tongue-nan-3m-Epithelial-suprabasal|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 METRNL ADGRL2 F3 MOCOS

4.41e-05190915719a5cecc3e8001ca9c38165258b5ff9c800713a
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

CHL1 ADGRF5 ADGRL2 ZFPM2 ADGRL4

4.53e-05191915f229abf69a1217194f74b0502486907e07dba989
ToppCellEndothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|World / Lineage, Cell type, age group and donor

CHL1 ADGRF5 ADGRL2 ZFPM2 ADGRL4

4.64e-051929151e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

RPL37A UNC5C TRPS1 LRP1B ZFPM2

4.87e-0519491585e00861c5068a27d0cf0ae677f420c8245baa9a
ToppCellGlobus_pallidus-Hematopoietic-MACROPHAGE|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CD22 ADGRE3 OAS3 CD200R1

4.89e-0598914fcb9da8b676f57facfdfc0ccaca585acaa6396f2
ToppCellGlobus_pallidus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CD22 ADGRE3 OAS3 CD200R1

4.89e-0598914dd6e81120ff27961da766f47a251688ee8390b90
ToppCellGlobus_pallidus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CD22 ADGRE3 OAS3 CD200R1

4.89e-05989148ff05867d623fa13c361789fe76634ce1f4a9354
ToppCellGlobus_pallidus-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CD22 ADGRE3 OAS3 CD200R1

4.89e-05989140a4198a806cf9a143d546555f5e0bef2f2b6fd6e
ToppCellGlobus_pallidus-Hematopoietic-MACROPHAGE-MP1(C1qb)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

CD22 ADGRE3 OAS3 CD200R1

4.89e-05989147e24ebfe74d1bd6af78b0b9d7c10852d49f85cf9
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHL1 JPH2 F3 CHRNA1 RYR3

5.12e-05196915b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellcritical-Epithelial-Secretory|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CHL1 CTSC ELAPOR1 F3 SORL1

5.12e-05196915dbf14f5851c2b779a8b35e820c4584ea9096e49d
ToppCellCOVID-19-Epithelial-Club,_Basal_cells|Epithelial / Condition, Lineage and Cell class

CHL1 CTSC ELAPOR1 F3 SORL1

5.24e-0519791578ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCellcontrol-Epithelial-Secretory|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CHL1 CTSC ELAPOR1 F3 SORL1

5.50e-05199915262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Astrocyte-Astrocyte-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

UNC5C F3 LRP1B KLKB1 RYR3

5.63e-0520091507d942803360e1a1e8e131d6e31c726dd0db1a0b
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC12A1 ADGRE3 UNC5C ELAPOR1

1.38e-0412891458639cfdc70ff6764adcc5c1ce9eba9d033b8209
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-Neu_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC12A1 ADGRE3 UNC5C ELAPOR1

1.38e-041289149b3c57d559a5ed8d590dd89b64a57a3227d8c684
ToppCellCOVID-19-kidney-Mito-rich_Int|kidney / Disease (COVID-19 only), tissue and cell type

C9orf57 EYS CTRB1 ZFPM2

1.42e-0412991457b705106aec7bbfc587de1ccd4f2335fc44dd6f
ToppCelldroplet-Skin-nan-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR89 PCDHA8 LARS2 F3

1.46e-041309144c8b931987432e8bcd39029d4fa124dc383ea355
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 PCDHA2 KLK5 SORL1

1.89e-0413991427dd36f5ef03fa97f0fdb19fbd259cb60e7962b3
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 PCDHA2 KLK5 SORL1

1.89e-041399142a54627947f8c6597c041f4785f8a4e52d0edfba
ToppCelldroplet-Pancreas-Exocrine-18m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 METRNL OAS3 CD200R1

2.05e-04142914bf4a9633d128805a0d7e426d6fe6c29db1ff8c81
ToppCelldroplet-Lung-nan-3m-Myeloid-intermediate_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 METRNL PRKCD OAS3

2.11e-041439144d11d53330a9197275a8851e1bbf55a113715a09
ToppCelldroplet-Lung-nan-3m-Myeloid-Intermediate_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 METRNL PRKCD OAS3

2.11e-041439148b9f4d87d5faac7752c83e1992491fc5550600f8
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASGRP4 SLU7 MOCOS SORL1

2.17e-041449141efa434e577d1f87e02df01667782f414d63bd60
ToppCellPND14-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RASGRP4 SLU7 MOCOS SORL1

2.17e-04144914c0c5f254a960ba5e5f1354599d54e77360e6c2ac
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-14|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHL1 CD22 GEN1 TBC1D9

2.41e-041489146ffa212f0cc44c40d2143816dc6cfd82fbf09a33
ToppCellImmune_cells-Monocytes|World / Lineage and Cell class

RASGRP4 CTSC ADGRE3 PRKCD

2.41e-04148914e8037e831a6b11b06073b4e76684eb61308822f1
ToppCelldroplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 METRNL PRKCD OAS3

2.53e-04150914b37f538ca5f976b509efe35dc81115b72b227084
ToppCelldroplet-Lung-3m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 METRNL PRKCD OAS3

2.53e-041509142c7518918c40e1bf679a2d4e83b472ee6f2f9df8
ToppCellCOVID-19-Epithelial_cells-Airway_mucous|COVID-19 / group, cell type (main and fine annotations)

DNAI2 ELAPOR1 CDC20B CFHR4

2.60e-041519148216462e723fec2797387929dde095370947e10a
ToppCelldroplet-Lung-nan-3m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 METRNL WDR89 PRKCD

2.60e-04151914c743dc8758416a4f562d60c8fd2df7e659ab6951
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

PCDHA12 ADGRF5 ZFPM2 ADGRL4

2.80e-04154914511923b27469ea20f8bd82a9ec27119a6e884644
ToppCelldroplet-Fat-Scat-21m-Myeloid|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

METRNL CTSC PRKCD CD200R1

3.09e-04158914c8df636412a08c570f235c34d4cff46924a9b11d
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Endothelial-Endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A WDR89 ADGRF5 ADGRL4

3.09e-04158914ba9998cbf786c515d30fe42de02c7a246db1b6f9
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR85 TRPS1 PRKCD CHRNA1

3.09e-04158914bd37d567754b660bfff7aef81cb307a384ec20a0
ToppCelldroplet-Fat-Scat-21m-Myeloid-myeloid_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

METRNL CTSC PRKCD CD200R1

3.09e-04158914718eafcf8a171bb69b402dc9d69564c3521a62a9
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Endothelial-endothelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A WDR89 ADGRF5 ADGRL4

3.09e-04158914a2efcc184ef13d81373e3690253ba35f6be09c5f
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Endothelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A WDR89 ADGRF5 ADGRL4

3.09e-04158914e52eff2bd1e7e0ce9c278ed5109802865e0fe69c
ToppCellfacs-Lung-EPCAM-18m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 OAS3 ADAM30 SORL1

3.16e-04159914baf843dc44b072504eb1d28de55b1ee67aeec32b
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASGRP4 OAS3 ADAM30 SORL1

3.16e-041599149eb78202b9a4e8217f00e64d5142ed28c00abd04
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHL1 ELAPOR1 CDC20B F3

3.16e-0415991460b1f4dce2ce0911160fda17f137c064da31e2eb
ToppCelldroplet-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l1-4|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CD22 CTSC PRKCD OAS3

3.24e-041609146329b0f02f9509086e563c2ed762a8ec693883b5
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 IL31RA METRNL PRKCD

3.24e-04160914bc4a93dc5f37829799c37877e751ff3bc122e4ab
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TECTA LARS2 LRP1B KLKB1

3.39e-04162914bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellfacs-Lung-nan-3m-Myeloid-Nonclassical_Monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL31RA METRNL PRKCD LARS2

3.39e-041629143fd6aaf0fbaffc7ab38aa25e46c37ef511e1e704
ToppCellfacs-Lung-nan-3m-Myeloid-non-classical_monocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IL31RA METRNL PRKCD LARS2

3.39e-041629148134f73eb76693f4f1845f643042fdc1e81c274c
ToppCellPND07-28-samps-Myeloid-Macrophage|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CTSC LARS2 TBC1D9 CD200R1

3.39e-041629147c73fe8388af370461e04097cf145cbc9847285b
ToppCellControl-APC-like-Monocytes|Control / group, cell type (main and fine annotations)

CD22 VNN2 ADGRE3 MED14

3.47e-041639144bc80a2c741d462724b6f3902377d48c57478932
ToppCelldroplet-Lung-30m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RASGRP4 CTSC PRKCD OAS3

3.55e-04164914f88871d3b9307112eb7ced4c629f5704326ecae8
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

UNC5C DNAI2 PCDHA2 F3

3.55e-04164914a764b79a127c8f360af0b79a1da64658badf0dfa
ToppCellfacs-Lung-nan-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACAD11 CD22 PRKCD OAS3

3.72e-041669145c132f505dc5f699c87913f140344fc9f8e7e0f5
ToppCellmild_COVID-19_(asymptomatic)-B_intermediate|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

TDRD15 CD22 PCDHA4 GEN1

3.72e-041669148de8f388f24436b84e19ef460476fdbda4d16abf
ToppCellfacs-BAT-Fat-24m-Myeloid|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 CELA1 CTRB1 LARS2

3.72e-04166914001a31aaa4ab4d5606b894faf6fcaad524405064
ToppCellfacs-BAT-Fat-24m-Myeloid-myeloid_cell|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 CELA1 CTRB1 LARS2

3.72e-0416691431ed1290b4a977eabfc29674a5c593985bff6a74
ToppCellfacs-BAT-Fat-24m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 CELA1 CTRB1 LARS2

3.72e-04166914c71ad3fc6a14507609d17756431d3deff9fda418
ToppCellfacs-Brain_Myeloid-Cerebellum_-18m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 CD22 CTSC LARS2

3.72e-041669144ab1959c526c2fd83077fc03e4de207f34841a19
ToppCellAdult-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D231|Adult / Lineage, Cell type, age group and donor

CHL1 ADGRL2 LRP1B ADGRL4

3.81e-041679145af9127bae05768a5164d5708a4ad37edca99324
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

NOL4 LHFPL4 ELAPOR1 UNC79

3.81e-04167914c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCelldroplet-Fat-Scat-18m-Myeloid-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTSC CELA1 PRKCD CD200R1

3.89e-04168914749eccebe4ee066f827d2a3980512f195f23ac27
ToppCellhealthy_donor-Myeloid-Monocytic-Neutrophil|healthy_donor / Disease condition, Lineage, Cell class and subclass

VNN2 ADGRE3 ELAPOR1 PCDHA13

3.89e-0416891404259f5a9b067cd1b5619e34591e4b2fccc18535
Drugphenyl 4-guanidinobenzoate

CTRB2 CELA1 CTRB1 F3 KLKB1

1.08e-0913905CID003015798
DrugONO-3307

CTRB2 CELA1 CTRB1 F3 KLKB1

2.51e-0915905CID000127139
Drugc140

CTRB2 CTRB1 F3

5.97e-083903CID002783250
DrugFK-386

CTRB2 CTRB1 KLKB1

5.97e-083903CID000135044
DrugFK-375

CTRB2 CTRB1 KLKB1

5.97e-083903CID000135042
DrugC18 4

CTRB2 CTRB1 F3

5.97e-083903CID000077248
DrugFK-316

CTRB2 CTRB1 KLKB1

5.97e-083903CID000133688
DrugFK-448

CTRB2 CTRB1 KLKB1

5.97e-083903CID006917869
DrugS 2484

CTRB2 CELA1 CTRB1 F3

2.22e-0714904CID000135164
Drugalpha-amyrin palmitate

CTRB2 CELA1 CTRB1

2.38e-074903CID000185477
DrugNSC-676827

CTRB2 CELA1 CTRB1

2.38e-074903CID000385555
DrugDABITC

CTRB2 CELA1 CTRB1 KLKB1

3.01e-0715904CID000082084
Drugp-nitroaniline

CTSC CTRB2 CELA1 CTRB1 F3 KLKB1

3.45e-0770906CID000007475
Drugmethylcyclopentadienyl manganese tricarbonyl

CTRB2 CELA1 PRKCD CTRB1

5.22e-0717904CID000025511
DrugZ-Phe-Leu

CTRB2 CELA1 CTRB1

5.94e-075903CID000333351
DrugAC1L3F57

CTRB2 CELA1 CTRB1

5.94e-075903CID000139565
DrugMaap-borov

CTRB2 CELA1 CTRB1

5.94e-075903CID005486914
Drugchloromethyl

CAPN7 CTRB2 CELA1 PRKCD CTRB1 F3 KLKB1 CAPN15

1.07e-06195908CID000007835
Drugoctyl isocyanate

CTRB2 CELA1 CTRB1

1.18e-066903CID000076616
DrugMaap-borof

CTRB2 CELA1 CTRB1

1.18e-066903CID005492190
Drugcobalt;(6E)-6-[[2-[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]ethylamino]methylene]cyclohexa-2,4-dien-1-one;hydrate

CTRB2 CELA1 CTRB1

1.18e-066903CID011810022
DrugD-gluconyl-glycine azide

CTRB2 CELA1 CTRB1

1.18e-066903CID000194550
Drugbz-Ala-OMe

CTRB2 CELA1 CTRB1

1.18e-066903CID000023671
DrugAC1L4DZ7

CTRB2 CELA1 CTRB1

1.18e-066903CID000155288
DrugN-carbobenzoxy-l-alanine

CTRB2 CELA1 CTRB1 F3

1.58e-0622904CID000070832
DrugCbz-phe-arg-chn2

CTRB2 CTRB1 KLKB1

2.07e-067903CID005492392
DrugEACA

RPL37A CTRB2 CELA1 KLK5 CTRB1 F3 KLKB1

2.31e-06151907CID000000564
DrugN-chlorosuccinimide

CD22 CTRB2 CELA1 CTRB1 KLKB1

2.81e-0656905CID000031398
DrugBAPNA

CTRB2 CELA1 CTRB1 KLKB1 RYR3

3.07e-0657905CID000013494
Drug3-(4-sulfamoylphenyl)propanoic acid

CTRB2 CELA1 CTRB1

3.30e-068903CID003161908
DrugZ-Phe-OMC

CTRB2 CELA1 CTRB1

3.30e-068903CID000127395
DrugBOC-Ala-OMC

CTRB2 CELA1 CTRB1

3.30e-068903CID000132159
Drug2-methylproline

CTRB2 CELA1 CTRB1

3.30e-068903CID000095491
Drug7-amino-4-methylcoumarin

CTSC CTRB2 CELA1 CTRB1 KLKB1

3.65e-0659905CID000092249
DrugZPCK

CTRB2 CELA1 CTRB1

4.93e-069903CID000099625
DrugAppna

CTSC CTRB2 CTRB1

4.93e-069903CID006453929
Drugpyrenebutyl methylphosphonofluoridate

CTRB2 CELA1 CTRB1

4.93e-069903CID000125653
DrugFK-401

CTRB2 CTRB1 KLKB1

4.93e-069903CID000135041
Drug3-chloroisocoumarin

CTRB2 CELA1 CTRB1

4.93e-069903CID000560737
DrugRD4-6205

CTRB2 CELA1 CTRB1

7.03e-0610903CID003002865
Drugfuroyl saccharin

CTRB2 CELA1 CTRB1

9.63e-0611903CID000064792
Drugalpha-amyrin linoleate

CTRB2 CELA1 CTRB1

9.63e-0611903CID005318324
Drugbenzyl sulfonate

CTRB2 CTRB1 KLKB1

9.63e-0611903CID000007532
DrugBoroval

CTRB2 CELA1 CTRB1

9.63e-0611903CID005487930
Drugcyanogen-bromide

CTSC CTRB2 CTRB1 KLKB1

9.67e-0634904CID000010476
DrugAC1NRA23

CTSC CTRB2 CELA1 CTRB1 KLKB1

1.05e-0573905CID005287657
DrugNSC187724

CTRB2 CELA1 CTRB1 KLKB1

1.09e-0535904CID000426387
DrugLlvy-mca

CTSC CTRB2 REG1A CTRB1

1.09e-0535904CID000121886
DrugLMWH

RPL37A CTSC CTRB2 CELA1 KLK5 CTRB1 F3 KLKB1 CHRNA1 RYR3 ADGRL4 CFHR4

1.16e-056639012CID000000772
DrugLeupeptin hydrochloride

CAPN7 CTSC CTRB2 CELA1 KLK5 CTRB1 KLKB1 CAPN15

1.38e-05276908CID000003910
Drugurinastatin

CTRB2 CELA1 CTRB1 F3 KLKB1

1.54e-0579905CID000105102
DrugBOCPheONP

CTRB2 CTRB1

1.55e-052902CID000111308
DrugMPM-06

CTRB2 CTRB1

1.55e-052902CID000161546
DrugNSC-374899

CTRB2 CTRB1

1.55e-052902CID000435726
Drugmethylbenzenebutanoate

CTRB2 CTRB1

1.55e-052902CID000281254
DrugAsp-Arg-Val-Tyr-Val-His-Pro-Phe-His-Leu

CTRB2 CTRB1

1.55e-052902CID004418081
Drugc189

CTRB2 CTRB1

1.55e-052902CID000248048
Drugdansyl-D-arginine methyl ester

CTRB2 CTRB1

1.55e-052902CID000191369
Drugmethyl 6-phenylhexanoate

CTRB2 CTRB1

1.55e-052902CID011820300
Drug5-aminotetrazole

CTRB2 CTRB1

1.55e-052902CID000020467
Drug2-bromoisobutyric acid

CTRB2 CTRB1

1.55e-052902CID000074924
Drugp-toluamidine

CTRB2 CTRB1

1.55e-052902CID000122753
DrugN-acetyl-alpha-azaphenylalanine phenyl ester

CTRB2 CTRB1

1.55e-052902CID000191275
Drugisobutyl sulfide

CTRB2 CTRB1

1.55e-052902CID000011607
Drugmangrove

CTSC GPR85 CTRB2 PRKCD CTRB1 F3 LRP1B CHRNA1 SORL1 CFHR4

1.61e-054689010CID000000965
Drug4-chloro-3-ethoxy-7-guanidinoisocoumarin

CELA1 F3 KLKB1

1.66e-0513903CID000196678
Drugp-aminobenzamidine

CTRB2 CELA1 CTRB1 F3 KLKB1

1.74e-0581905CID000001725
Drugphenylalanine

RPL37A CTSC CTRB2 MAPK1 CTRB1 F3 KLKB1

1.89e-05208907CID000000994
DrugTyr-D-Ala-Phe-Phe-NH2

CTRB2 CELA1 CTRB1

2.11e-0514903CID004584008
DrugErp tripeptide

CTRB2 CELA1 CTRB1

2.11e-0514903CID000131430
Drugogen

CTRB2 CTRB1 F3 KLKB1

3.28e-0546904CID000023703
DrugATEE

CTRB2 CELA1 CTRB1 KLKB1

3.58e-0547904CID000002004
DrugAC1L2TMY

CTRB2 CELA1 CTRB1

3.90e-0517903CID000102826
Drugkazinol B

CTRB2 CTRB1 RYR3

3.90e-0517903CID000480869
DrugTLCK

CTRB2 CELA1 PRKCD KLK5 CTRB1 KLKB1

3.91e-05158906CID000004427
DrugN-acetylbenzotriazole

CTRB2 CTRB1

4.62e-053902CID000087784
Drugphotophor

CTRB2 CTRB1

4.62e-053902CID000014780
Drugdibutyl iodomethaneboronate

CTRB2 CTRB1

4.62e-053902CID000098591
Drugzinc;dipicolinate

CTRB2 CTRB1

4.62e-053902CID004309911
Drug2-oxobut-3-ynoate

CTRB2 CTRB1

4.62e-053902CID000171547
DrugTfa-phe-ala

CELA1 F3

4.62e-053902CID005489523
DrugAFMeq

CTRB2 CTRB1

4.62e-053902CID000194069
DrugBz-Cti-otbu

CTRB2 CTRB1

4.62e-053902CID006452691
Drugn-(2-oxoethyl)benzamide

CTRB2 CTRB1

4.62e-053902CID000188995
DrugAC1L49DM

CTRB2 CTRB1

4.62e-053902CID000152933
DrugBenzamidomethaneboronic acid

CTRB2 CTRB1

4.62e-053902CID000127677
Drugphenyl hippurate

CTRB2 CTRB1

4.62e-053902CID000076323
Drugcarbostyril-124

CTRB2 CTRB1

4.62e-053902CID000088277
DrugN-trifluoroacetyl-4-fluorophenylalanine

CTRB2 CTRB1

4.62e-053902CID000328214
Drugtaraxastane

CTRB2 CTRB1

4.62e-053902CID006429404
DrugPhe-phe-ome

CTRB2 CTRB1

4.62e-053902CID000151728
Drugphenylethaneboronic acid

CTRB2 CTRB1

4.62e-053902CID000065389
Drug3-amino-2-pyridone

CTRB2 CTRB1

4.62e-053902CID000322353
DrugASA-BMPA

CTRB2 CTRB1

4.62e-053902CID003035649
Drugp-nitrophenyl benzoate

CTRB2 CTRB1

4.62e-053902CID000070396
DrugZ-Phe-OMe

CTRB2 CTRB1

4.62e-053902CID003082435
Drug3-methylcoumarin

CTRB2 CTRB1

4.62e-053902CID000017130
Drug2-propyl methylphosphonochloridate

CTRB2 CTRB1

4.62e-053902CID000102124
DrugAC1L19T8

CTRB2 CTRB1

4.62e-053902CID000000694
DrugMarinostatin D

CTRB2 CTRB1

4.62e-053902CID000132206
Disease1,5 anhydroglucitol measurement

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

2.22e-1429908EFO_0008009
Diseasevisceral adipose tissue measurement, body mass index

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

2.62e-1087908EFO_0004340, EFO_0004765
Diseaseneutrophil count, basophil count

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

4.42e-07224908EFO_0004833, EFO_0005090
Diseasepost-traumatic stress disorder symptom measurement

PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

5.35e-0682905EFO_0008535
Diseaseneuroticism measurement, cognitive function measurement

PCDHA9 TRPS1 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2 LRP1B

9.01e-065669010EFO_0007660, EFO_0008354
Diseaselevel of chymotrypsinogen B2 in blood serum

CTRB2 CTRB1

9.20e-062902OBA_2041192
Diseaseneutrophil count

PCDHA9 TCHP ELAPOR1 CELA1 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 ADGRF5 PCDHA3 PCDHA2 ADGRL2 ZFPM2 ADGRL4

1.78e-0513829015EFO_0004833
Diseasechymotrypsinogen B measurement

CTRB2 CTRB1

2.75e-053902EFO_0801477
Diseasepost-traumatic stress disorder

CTSC PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2

3.69e-05202906EFO_0001358
DiseaseAbnormality of refraction

PCDHA9 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2 TAFA4 MOCOS

3.95e-056739010HP_0000539
Diseasenephrotic syndrome type 20 (implicated_via_orthology)

TBC1D9B TBC1D9

5.50e-054902DOID:0070357 (implicated_via_orthology)
Diseasekallikrein-5 measurement

KLK5 CFHR4

5.50e-054902EFO_0020515
Diseasepulse pressure measurement

TDRD15 PCDHA9 TCHP TRPS1 WDR55 JPH2 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2 ZFPM2

7.95e-0513929014EFO_0005763
DiseaseHypoplastic Left Heart Syndrome

PCDHA9 PCDHA13

9.15e-055902C0152101
Diseasevital capacity

PCDHA9 RPL37A METRNL JPH2 PCDHA13 PCDHA12 PCDHA8 PCDHA6 PCDHA4 PCDHA3 PCDHA2 ADGRL2 ADGRL4

9.41e-0512369013EFO_0004312
Diseasecomplement factor H-related protein 2 measurement

CHL1 REG1A CFHR4

9.47e-0529903EFO_0600055
Diseasebirth measurement, spontaneous preterm birth

ADGRL2 SORL1

1.91e-047902EFO_0006917, EFO_0006921
Diseasecoiled-coil domain-containing protein 80 measurement

KLKB1 CD200R1

2.55e-048902EFO_0020268
DiseaseHMG CoA reductase inhibitor use measurement

TDRD15 TRPS1 UGT2B10 CTRB2 CTRB1

2.89e-04189905EFO_0009932
Diseasecorneodesmosin measurement

TRPS1 ZFPM2

3.27e-049902EFO_0801499
Diseasedepressive symptom measurement

NOL4 PCDHA6 PCDHA4 PCDHA3 PCDHA2 HERC1 ADGRL4

3.32e-04426907EFO_0007006
DiseaseAlzheimer disease, dementia, family history of Alzheimer’s disease

TRPS1 DNAI2 ZFPM2

4.30e-0448903EFO_0009268, MONDO_0001627, MONDO_0004975
Diseasetrypsin-2 measurement

CTRB2 CTRB1

4.97e-0411902EFO_0008305
DiseaseAlzheimer disease, gastroesophageal reflux disease

PCDHA4 PCDHA3 PCDHA2 ADGRL2 SORL1

6.80e-04228905EFO_0003948, MONDO_0004975
Diseasecommon carotid intimal medial thickness

TDRD15 SLU7 RYR3

1.14e-0367903EFO_0004860
Diseaseepilepsy (implicated_via_orthology)

CHL1 SLC12A1 MIB1 LRP1B

1.59e-03163904DOID:1826 (implicated_via_orthology)
Diseasecoagulation factor measurement

F3 CFHR4

1.69e-0320902EFO_0004634
Diseasefumarate measurement

EYS LARS2

1.86e-0321902EFO_0010480
Diseaseactivities of daily living score measurement

NOL4 TRPS1

1.86e-0321902EFO_0008451
Diseaseproprotein convertase subtilisin/kexin type 9 measurement

TDRD15 ADGRL4

2.04e-0322902EFO_0009312
Diseasedaytime rest measurement

NOL4 LHFPL4 ZNF556 ZFPM2 CD200R1

2.12e-03295905EFO_0007828
Diseasearginine measurement

DNAI2 KLKB1

2.23e-0323902EFO_0020990
Diseaseserum iron measurement

UNC5C F3 LRP1B

2.34e-0386903EFO_0006332
Diseaseinfluenza A (H1N1)

TRPS1 ADGRL2 LRP1B

2.42e-0387903EFO_1001488

Protein segments in the cluster

PeptideGeneStartEntry
TTYKDCKVWPGGSRT

AAMDC

21

Q9H7C9
YGTTKVCWLSTENNF

ADGRL4

556

Q9HBW9
GTLCATTGWGKTKYN

CTRB2

151

Q6GPI1
YWSTQGCKLVDTNKT

ADGRL2

801

O95490
VYGTIWLQSKTGTEC

DNAI2

266

Q9GZS0
IGAGYCKRQVSTWTK

ACAD11

171

Q709F0
SGDSWTKQVTCRYFK

MKRN4P

86

Q13434
KPTLVCSSAVGSWSY

PCDHA9

736

Q9Y5H5
KPTLVCSSAVGSWSY

PCDHA2

736

Q9Y5H9
KPTLVCSSAVGSWSY

PCDHA6

736

Q9UN73
NCSMKLGTWTYDGSV

CHRNA1

161

P02708
GAYQVRLCKDGTWTT

CAPN15

581

O75808
GWYKACKVSSPTVNT

KLC4

451

Q9NSK0
NSKGYTKSIDIWSVG

MAPK1

201

P28482
VSSTQGKWKAFSTCG

OR1S1

241

Q8NH92
KPTLVCSSAVGSWSY

PCDHA8

736

Q9Y5H6
KPTLVCSSAVGSWSY

PCDHA3

736

Q9Y5H8
IRQSSSSGAKYEGTW

JPH2

96

Q9BR39
KLYWISSGNGTINRC

LRP1B

1746

Q9NZR2
GSLGQWVKNTCATYA

MAGEC3

16

Q8TD91
KSYRCECTSGWTGQN

EYS

791

Q5T1H1
TLGWVGRYCENKTSF

EYS

2961

Q5T1H1
SYSCWVENAIGKTAV

CHL1

491

O00533
KNLTCTWSPGKETSY

IL31RA

36

Q8NI17
SGTYGKIWEGSSKCN

PRKCD

331

Q05655
TGNCTSSKWVPRGDY

ELAPOR1

151

Q6UXG2
NCIVYSKGGQLWCTT

ZFPM2

171

Q8WW38
GLASTGVTSGCYQWK

HERC1

2061

Q15751
SCSGFLWGVTKQGYR

RASGRP4

556

Q8TDF6
CATKQEYWSNGTVTV

CD200R1

186

Q8TD46
EYWSNGTVTVKSTCH

CD200R1

191

Q8TD46
VSTYDCGEKISSWLS

MOCOS

681

Q96EN8
AGTKCLVSGWGTTKS

KLK5

181

Q9Y337
QYSSDRCSWKGSGLT

METRNL

46

Q641Q3
NNSPCYITGWGKTKT

CELA1

141

Q9UNI1
GGAWTYNTTSAVTVK

RPL37A

66

P61513
AKTGKYSLGDCSVRW

LHFPL4

161

Q7Z7J7
CYGTTKGSSISIQWN

MED14

811

O60244
CGTSWTYNPAAVSKV

MIB1

386

Q86YT6
VSSTQGKWKAFSTCG

OR1S2

241

Q8NGQ3
KPTLVCSSAAGSWSY

PCDHA13

736

Q9Y5I0
KPTLVCSSAVGSWSY

PCDHA4

736

Q9UN74
GYVTNKSVSVWSVAG

QTRT2

106

Q9H974
GGSNTNWKTLYEVKS

RPA1

436

P27694
AWSFGKVCSLEYAGS

ADAM30

306

Q9UKF2
YTLSKRINGKWSGQS

CAPN7

686

Q9Y6W3
GSKVTTYCNETMTGW

CTSC

111

P53634
LQGSKYVTCSNGDWS

CFHR4

246

Q92496
LTCNYISSVSWIKEG

CDC20B

271

Q86Y33
QSRYGSSGKSWSQKT

GEN1

91

Q17RS7
SKGDTSTIYTNCWVT

KLKB1

506

P03952
VKNGSTWTYGTLTCK

GPR85

81

P60893
GGIQWYSVKGCTKNT

C9orf57

116

Q5W0N0
NSAGLGVYSSKVTEW

SDK2

771

Q58EX2
GTLCATTGWGKTKYN

CTRB1

151

P17538
GQTSGSVWSSYRKSC

DCAF15

541

Q66K64
AYWCQGTNSVGKGRS

CD22

656

P20273
KPTLVCSSAVGSWSY

PCDHA12

736

Q9UN75
YCVSLTSSTGFQKWK

REG1A

136

P05451
HWYQQCTKISKGRGS

OAS3

951

Q9Y6K5
DYSGWSCSSGNKVKT

TAFA4

121

Q96LR4
SKTNVYISSSAGARW

SORL1

516

Q92673
CTRSIYSATGKWTKE

LARS2

36

Q15031
EIGQTACVAKYSGKW

TDRD15

801

B5MCY1
YSGKWCRAAVLTQVS

TDRD15

811

B5MCY1
SGWGKISKTSEYSNV

OVCH1

176

Q7RTY7
YVTCKKPDVNWGSST

SLC12A1

641

Q13621
FQDWCLRTYGDSGKT

NOL4

11

O94818
SKVCYQLVLSSWVTG

OR6C6

136

A6NF89
GYNRDTSGWKVVKTS

STARD6

16

P59095
YWTVACGSSRKEITK

TBC1D9B

71

Q66K14
KVFCVYWKSTGQGSQ

ADGRE3

301

Q9BY15
TVKTSTREWNGTYHC

ADGRF5

531

Q8IZF2
GITVTGWRNYTSCTV

TECTA

1356

O75443
GRWYTKDSLYSSCGT

VNN2

481

O95498
TTKTSLWRKNANGGY

TRPS1

901

Q9UHF7
TWKGCLSNFSSYLTK

TRIM13

346

O60858
CDKSQSGWKYGISLD

RYR3

2631

Q15413
FGTIRSTTCVYKGKW

RNF123

121

Q5XPI4
ASKNWKLSIRCGGYT

SP100

651

P23497
DSLVYWTIACGGSRK

TBC1D9

71

Q6ZT07
KCETCGKTYGWSSSL

ZNF556

371

Q9HAH1
SSSGEWYKRGVKENS

SLU7

96

O95391
ICSSKQAEWSSKTSY

TCHP

46

Q9BT92
STKSGDWKSKCFYTT

F3

71

P13726
CLIESYRGTSDWKNS

TIMM22

141

Q9Y584
YRGTSDWKNSVISGC

TIMM22

146

Q9Y584
WGKKVACGSSEGTIY

WDR55

221

Q9H6Y2
YFSSGSCGKVLVWAA

UGT2B10

16

P36537
ISSVSCIGWSGKGYK

WDR89

216

Q96FK6
GATIISSYCKSKGWQ

TTLL10

166

Q6ZVT0
SSYCKSKGWQRIHDS

TTLL10

171

Q6ZVT0
AWSSAGTTKSRKAYV

UNC5C

146

O95185
TSKWTVDYLSQVGGK

TYW5

41

A2RUC4
VGGYWDKSCSTVTQL

UNC79

586

Q9P2D8
GKLSCSTWNYQKSTI

WDR36

466

Q8NI36