Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	DUOX1 MCTP1 PLA2G4C PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 EGFLAM PCDHGA8 F9 LETM1 CEMIP2 PROS1	8.84e-07	749	88	15	GO:0005509
GeneOntologyMolecularFunction	isocitrate dehydrogenase (NADP+) activity	IDH1 IDH2	1.92e-05	2	88	2	GO:0004450
GeneOntologyMolecularFunction	complement receptor activity	GPR32 GPR32P1 C5AR2	2.91e-05	14	88	3	GO:0004875
GeneOntologyMolecularFunction	isocitrate dehydrogenase [NAD(P)+] activity	IDH1 IDH2	1.90e-04	5	88	2	GO:0004448
GeneOntologyMolecularFunction	N-formyl peptide receptor activity	GPR32 GPR32P1	1.90e-04	5	88	2	GO:0004982
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	1.43e-05	187	87	7	GO:0007156
GeneOntologyBiologicalProcess	glyoxylate cycle	IDH1 IDH2	1.76e-05	2	87	2	GO:0006097
GeneOntologyBiologicalProcess	complement receptor mediated signaling pathway	GPR32 GPR32P1 C5AR2	3.90e-05	16	87	3	GO:0002430
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 MDGA1 PCDHGA8	5.31e-05	313	87	8	GO:0098742
HumanPheno	Thrombophlebitis	PIEZO1 IDH1 IDH2 F9 PROS1	5.25e-05	87	25	5	HP:0004418
HumanPheno	Venous thrombosis	PIEZO1 IDH1 IDH2 F9 PROS1	5.25e-05	87	25	5	HP:0004936
HumanPheno	D-2-hydroxyglutaric aciduria	IDH1 IDH2	6.92e-05	3	25	2	HP:0012321
HumanPheno	Exostoses	COL11A2 IDH1 IDH2	1.31e-04	21	25	3	HP:0100777
HumanPheno	Prolonged whole-blood clotting time	VWF F9	1.38e-04	4	25	2	HP:0005542
HumanPheno	Deep venous thrombosis	PIEZO1 F9 PROS1	1.51e-04	22	25	3	HP:0002625
Domain	Cadherin_tail	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	3.71e-10	37	88	7	PF15974
Domain	Cadherin_CBD	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	3.71e-10	37	88	7	IPR031904
Domain	Cadherin_C	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	9.54e-10	42	88	7	IPR032455
Domain	Cadherin_C_2	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	9.54e-10	42	88	7	PF16492
Domain	Cadherin_2	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	2.26e-08	65	88	7	PF08266
Domain	Cadherin_N	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	2.26e-08	65	88	7	IPR013164
Domain	Cadherin_CS	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	8.17e-07	109	88	7	IPR020894
Domain	CADHERIN_1	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	1.04e-06	113	88	7	PS00232
Domain	Cadherin	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	1.04e-06	113	88	7	PF00028
Domain	CADHERIN_2	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	1.11e-06	114	88	7	PS50268
Domain	-	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	1.11e-06	114	88	7	2.60.40.60
Domain	CA	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	1.17e-06	115	88	7	SM00112
Domain	Cadherin-like	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	1.24e-06	116	88	7	IPR015919
Domain	Cadherin	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	1.40e-06	118	88	7	IPR002126
Domain	Isocitrate_DH_NADP	IDH1 IDH2	2.19e-05	2	88	2	IPR004790
Domain	Laminin_G_2	COL5A1 COL11A2 EGFLAM PROS1	3.69e-05	40	88	4	PF02210
Domain	LamG	COL5A1 COL11A2 EGFLAM PROS1	5.41e-05	44	88	4	SM00282
Domain	LRR_6	NOD1 CIITA FBXL14 NLRC5	1.31e-04	55	88	4	PF13516
Domain	Laminin_G	COL5A1 COL11A2 EGFLAM PROS1	1.61e-04	58	88	4	IPR001791
Domain	NACHT	NOD1 CIITA NLRC5	1.67e-04	23	88	3	PS50837
Domain	NACHT_NTPase	NOD1 CIITA NLRC5	1.67e-04	23	88	3	IPR007111
Domain	Iso_dh	IDH1 IDH2	2.17e-04	5	88	2	SM01329
Domain	IDH_IMDH	IDH1 IDH2	2.17e-04	5	88	2	PS00470
Domain	Isocitrate/isopropylmalate_DH	IDH1 IDH2	2.17e-04	5	88	2	IPR001804
Domain	Iso_dh	IDH1 IDH2	2.17e-04	5	88	2	PF00180
Domain	IsoPropMal-DH-like_dom	IDH1 IDH2	2.17e-04	5	88	2	IPR024084
Domain	IsoCit/isopropylmalate_DH_CS	IDH1 IDH2	2.17e-04	5	88	2	IPR019818
Domain	-	IDH1 IDH2	2.17e-04	5	88	2	3.40.718.10
Domain	LAM_G_DOMAIN	COL5A1 EGFLAM PROS1	7.57e-04	38	88	3	PS50025
Domain	Formyl_rcpt-rel	GPR32 C5AR2	9.64e-04	10	88	2	IPR000826
Domain	-	COL5A1 COL11A2 EGFLAM PROS1	1.06e-03	95	88	4	2.60.120.200
Domain	Fib_collagen_C	COL5A1 COL11A2	1.17e-03	11	88	2	IPR000885
Domain	COLFI	COL5A1 COL11A2	1.17e-03	11	88	2	PF01410
Domain	NC1_FIB	COL5A1 COL11A2	1.17e-03	11	88	2	PS51461
Domain	Laminin_G_1	EGFLAM PROS1	1.17e-03	11	88	2	PF00054
Domain	Fib_collagen_C	COL5A1 COL11A2	1.17e-03	11	88	2	PD002078
Domain	COLFI	COL5A1 COL11A2	1.17e-03	11	88	2	SM00038
Domain	-	F9 PROS1	1.40e-03	12	88	2	4.10.740.10
Domain	Coagulation_fac_subgr_Gla_dom	F9 PROS1	1.40e-03	12	88	2	IPR017857
Domain	Gla	F9 PROS1	1.93e-03	14	88	2	PF00594
Domain	GLA	F9 PROS1	1.93e-03	14	88	2	SM00069
Domain	GLA_1	F9 PROS1	1.93e-03	14	88	2	PS00011
Domain	GLA_domain	F9 PROS1	1.93e-03	14	88	2	IPR000294
Domain	GLA_2	F9 PROS1	1.93e-03	14	88	2	PS50998
Domain	Leu-rich_rpt_Cys-con_subtyp	FBXL14 NLRC5	3.56e-03	19	88	2	IPR006553
Domain	LRR_CC	FBXL14 NLRC5	3.56e-03	19	88	2	SM00367
Domain	Zinc_finger_PHD-type_CS	BAZ1A CHD5 SP140	3.58e-03	65	88	3	IPR019786
Domain	ConA-like_dom	COL5A1 COL11A2 EGFLAM MDGA1 PROS1	3.77e-03	219	88	5	IPR013320
Domain	TSPN	COL5A1 COL11A2	5.21e-03	23	88	2	SM00210
Domain	PHD	BAZ1A CHD5 SP140	5.34e-03	75	88	3	PF00628
Domain	Znf_PHD-finger	BAZ1A CHD5 SP140	6.18e-03	79	88	3	IPR019787
Domain	PHD	BAZ1A CHD5 SP140	8.57e-03	89	88	3	SM00249
Domain	Znf_PHD	BAZ1A CHD5 SP140	9.11e-03	91	88	3	IPR001965
Domain	Leu-rich_rpt	NOD1 IGFALS CIITA FBXL14 NLRC5	9.13e-03	271	88	5	IPR001611
Pathway	REACTOME_INTRINSIC_PATHWAY_OF_FIBRIN_CLOT_FORMATION	VWF F9 PROS1	1.22e-04	23	60	3	M14766
Pathway	REACTOME_INTRINSIC_PATHWAY_OF_FIBRIN_CLOT_FORMATION	VWF F9 PROS1	1.22e-04	23	60	3	MM14557
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	COL5A1 COL11A2 LAMC3	2.74e-04	30	60	3	M27772
Pathway	REACTOME_DEFECTIVE_FACTOR_VIII_CAUSES_HEMOPHILIA_A	VWF F9	3.69e-04	7	60	2	M39000
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	COL5A1 COL11A2 VWF LAMC3	4.44e-04	84	60	4	M7098
Pathway	WP_CYTOSINE_METHYLATION	IDH1 IDH2	4.91e-04	8	60	2	M39348
Pathway	REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE	VWF F9 PROS1	6.01e-04	39	60	3	M2844
Pathway	REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE	VWF F9 PROS1	6.01e-04	39	60	3	MM14559
Pathway	REACTOME_TRANSPORT_OF_GAMMA_CARBOXYLATED_PROTEIN_PRECURSORS_FROM_THE_ENDOPLASMIC_RETICULUM_TO_THE_GOLGI_APPARATUS	F9 PROS1	6.29e-04	9	60	2	MM14614
Pathway	REACTOME_GAMMA_CARBOXYLATION_OF_PROTEIN_PRECURSORS	F9 PROS1	6.29e-04	9	60	2	MM14613
Pathway	KEGG_MEDICUS_REFERENCE_CITRATE_CYCLE_FIRST_CARBON_OXIDATION	IDH1 IDH2	6.29e-04	9	60	2	M47937
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	COL5A1 COL11A2 LAMC3	6.96e-04	41	60	3	M27778
Pathway	REACTOME_REMOVAL_OF_AMINOTERMINAL_PROPEPTIDES_FROM_GAMMA_CARBOXYLATED_PROTEINS	F9 PROS1	7.84e-04	10	60	2	M26977
Pathway	REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS	F9 PROS1	9.56e-04	11	60	2	M12484
Pathway	REACTOME_GAMMA_CARBOXYLATION_TRANSPORT_AND_AMINO_TERMINAL_CLEAVAGE_OF_PROTEINS	F9 PROS1	9.56e-04	11	60	2	MM14615
Pathway	WP_FOCAL_ADHESION	COL5A1 COL11A2 VWF LAMC3 PARVB	1.18e-03	187	60	5	MM15913
Pathway	WP_VITAMIN_K_METABOLISM_AND_ACTIVATION_OF_DEPENDENT_PROTEINS	F9 PROS1	1.35e-03	13	60	2	M45518
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	6.59e-10	68	93	7	11230163
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	9.93e-10	72	93	7	10380929
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	1.21e-09	74	93	7	10817752
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	1.60e-09	77	93	7	10835267
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	2.11e-09	80	93	7	10716726
Pubmed	IDH1/2 mutation is associated with seizure as an initial symptom in low-grade glioma: A report of 311 Chinese adult glioma patients.	IDH1 IDH2	7.07e-06	2	93	2	25524848
Pubmed	Bridging Cancer Biology with the Clinic: Comprehending and Exploiting IDH Gene Mutations in Gliomas.	IDH1 IDH2	7.07e-06	2	93	2	30194083
Pubmed	Metabolism unhinged: IDH mutations in cancer.	IDH1 IDH2	7.07e-06	2	93	2	21383741
Pubmed	IDH1 and IDH2 mutations in patients with acute myeloid leukemia: Suitable targets for minimal residual disease monitoring?	IDH1 IDH2	7.07e-06	2	93	2	30176240
Pubmed	Secondary glioblastomas with IDH1/2 mutations have longer glioma history from preceding lower-grade gliomas.	IDH1 IDH2	7.07e-06	2	93	2	23494632
Pubmed	IDH1/2 Mutants Inhibit TET-Promoted Oxidation of RNA 5mC to 5hmC.	IDH1 IDH2	7.07e-06	2	93	2	27548812
Pubmed	Vorasidenib, a Dual Inhibitor of Mutant IDH1/2, in Recurrent or Progressive Glioma; Results of a First-in-Human Phase I Trial.	IDH1 IDH2	7.07e-06	2	93	2	34078652
Pubmed	IDH1/IDH2 mutations define the prognosis and molecular profiles of patients with gliomas: a meta-analysis.	IDH1 IDH2	7.07e-06	2	93	2	23894344
Pubmed	High incidence of IDH mutations in acute myeloid leukaemia with cuplike nuclei.	IDH1 IDH2	7.07e-06	2	93	2	21480859
Pubmed	IDH-Mutant Tumors Vulnerable to PARP Inhibition.	IDH1 IDH2	7.07e-06	2	93	2	28228392
Pubmed	Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology.	IDH1 IDH2	7.07e-06	2	93	2	23361564
Pubmed	Clinical relevance of IDH1/2 mutant allele burden during follow-up in acute myeloid leukemia. A study by the French ALFA group.	IDH1 IDH2	7.07e-06	2	93	2	29472349
Pubmed	Study of mutations in IDH1 and IDH2 genes in a sample of gliomas from Colombian population.	IDH1 IDH2	7.07e-06	2	93	2	29874711
Pubmed	IDH mutation detection in formalin-fixed paraffin-embedded gliomas using multiplex PCR and single-base extension.	IDH1 IDH2	7.07e-06	2	93	2	22360629
Pubmed	Isocitrate dehydrogenase 1 and 2 mutations in cholangiocarcinoma.	IDH1 IDH2	7.07e-06	2	93	2	22503487
Pubmed	The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate.	IDH1 IDH2	7.07e-06	2	93	2	20171147
Pubmed	The implications of IDH mutations for cancer development and therapy.	IDH1 IDH2	7.07e-06	2	93	2	34131315
Pubmed	Enhancement of de novo lipogenesis by the IDH1 and IDH2-dependent reverse TCA cycle maintains the growth and angiogenic capacity of bone marrow-derived endothelial progenitor cells under hypoxia.	IDH1 IDH2	7.07e-06	2	93	2	38281628
Pubmed	Analysis of isocitrate dehydrogenase-1/2 gene mutations in gliomas.	IDH1 IDH2	7.07e-06	2	93	2	22166653
Pubmed	Molecular profiling of cholangiocarcinoma shows potential for targeted therapy treatment decisions.	IDH1 IDH2	7.07e-06	2	93	2	23391413
Pubmed	Prognostic impact of isocitrate dehydrogenase enzyme isoforms 1 and 2 mutations in acute myeloid leukemia: a study by the Acute Leukemia French Association group.	IDH1 IDH2	7.07e-06	2	93	2	20625116
Pubmed	Highly specific determination of IDH status using edited in vivo magnetic resonance spectroscopy.	IDH1 IDH2	7.07e-06	2	93	2	29126125
Pubmed	Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations.	IDH1 IDH2	7.07e-06	2	93	2	20142433
Pubmed	IDH1 and IDH2 mutations in gliomas.	IDH1 IDH2	7.07e-06	2	93	2	23532369
Pubmed	[IDH1/2 mutations in gliomas].	IDH1 IDH2	7.07e-06	2	93	2	22147457
Pubmed	Diagnostic use of IDH1/2 mutation analysis in routine clinical testing of formalin-fixed, paraffin-embedded glioma tissues.	IDH1 IDH2	7.07e-06	2	93	2	19915484
Pubmed	IDH2 compensates for IDH1 mutation to maintain cell survival under hypoxic conditions in IDH1‑mutant tumor cells.	IDH1 IDH2	7.07e-06	2	93	2	31257503
Pubmed	Differential prognostic effect of IDH1 versus IDH2 mutations in myelodysplastic syndromes: a Mayo Clinic study of 277 patients.	IDH1 IDH2	7.07e-06	2	93	2	22033490
Pubmed	hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins.	VAMP7 VPS41	7.07e-06	2	93	2	23322049
Pubmed	Sequencing IDH1/2 glioma mutation hotspots in gliomas and malignant peripheral nerve sheath tumors.	IDH1 IDH2	7.07e-06	2	93	2	24311631
Pubmed	The prognostic value of IDH mutations and MGMT promoter status in secondary high-grade gliomas.	IDH1 IDH2	7.07e-06	2	93	2	23015095
Pubmed	Absence of IDH mutation in colorectal cancers with microsatellite instability.	IDH1 IDH2	7.07e-06	2	93	2	26987944
Pubmed	Pyrosequencing of IDH1 and IDH2 mutations in brain tumors and non-neoplastic conditions.	IDH1 IDH2	7.07e-06	2	93	2	23111198
Pubmed	Insular primary glioblastomas with IDH mutations: Clinical and biological specificities.	IDH1 IDH2	7.07e-06	2	93	2	28116838
Pubmed	Acquired mutations in the genes encoding IDH1 and IDH2 both are recurrent aberrations in acute myeloid leukemia: prevalence and prognostic value.	IDH1 IDH2	7.07e-06	2	93	2	20538800
Pubmed	The potential for isocitrate dehydrogenase mutations to produce 2-hydroxyglutarate depends on allele specificity and subcellular compartmentalization.	IDH1 IDH2	7.07e-06	2	93	2	23264629
Pubmed	Cancer-associated IDH mutations induce Glut1 expression and glucose metabolic disorders through a PI3K/Akt/mTORC1-Hif1α axis.	IDH1 IDH2	7.07e-06	2	93	2	34516556
Pubmed	Non-small cell lung cancers with isocitrate dehydrogenase 1 or 2 (IDH1/2) mutations.	IDH1 IDH2	7.07e-06	2	93	2	29723602
Pubmed	Ollier disease and Maffucci syndrome are caused by somatic mosaic mutations of IDH1 and IDH2.	IDH1 IDH2	7.07e-06	2	93	2	22057236
Pubmed	Somatic mosaic IDH1 and IDH2 mutations are associated with enchondroma and spindle cell hemangioma in Ollier disease and Maffucci syndrome.	IDH1 IDH2	7.07e-06	2	93	2	22057234
Pubmed	IDH mutations in older patients with diffuse astrocytic gliomas.	IDH1 IDH2	7.07e-06	2	93	2	33137656
Pubmed	Enasidenib and ivosidenib in AML.	IDH1 IDH2	7.07e-06	2	93	2	32955829
Pubmed	NLR family member NLRC5 is a transcriptional regulator of MHC class I genes.	CIITA NLRC5	7.07e-06	2	93	2	20639463
Pubmed	Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups.	IDH1 IDH2	7.07e-06	2	93	2	25783747
Pubmed	Landscape of IDH1/2 mutations in Chinese patients with solid tumors: A pan-cancer analysis.	IDH1 IDH2	7.07e-06	2	93	2	34145795
Pubmed	Type and location of isocitrate dehydrogenase mutations influence clinical characteristics and disease outcome of acute myeloid leukemia.	IDH1 IDH2	7.07e-06	2	93	2	23039322
Pubmed	IDH1 and IDH2 mutations in gliomas.	IDH1 IDH2	7.07e-06	2	93	2	19469031
Pubmed	Reverse TCA cycle flux through isocitrate dehydrogenases 1 and 2 is required for lipogenesis in hypoxic melanoma cells.	IDH1 IDH2	7.07e-06	2	93	2	22360810
Pubmed	Characterisation of isocitrate dehydrogenase 1/isocitrate dehydrogenase 2 gene mutation and the d-2-hydroxyglutarate oncometabolite level in dedifferentiated chondrosarcoma.	IDH1 IDH2	7.07e-06	2	93	2	31609487
Pubmed	Association of Maximal Extent of Resection of Contrast-Enhanced and Non-Contrast-Enhanced Tumor With Survival Within Molecular Subgroups of Patients With Newly Diagnosed Glioblastoma.	IDH1 IDH2	7.07e-06	2	93	2	32027343
Pubmed	Long-term survival in primary glioblastoma with versus without isocitrate dehydrogenase mutations.	IDH1 IDH2	7.07e-06	2	93	2	23918605
Pubmed	IDH2 Mutation Analysis in Undifferentiated and Poorly Differentiated Sinonasal Carcinomas for Diagnosis and Clinical Management.	IDH1 IDH2	7.07e-06	2	93	2	31876581
Pubmed	IDH1 and IDH2 mutation analysis in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome.	IDH1 IDH2	7.07e-06	2	93	2	21997850
Pubmed	Significance of IDH mutations varies with tumor histology, grade, and genetics in Japanese glioma patients.	IDH1 IDH2	7.07e-06	2	93	2	22136423
Pubmed	Isocitrate dehydrogenase gene mutations and 2-hydroxyglutarate accumulation in esophageal squamous cell carcinoma.	IDH1 IDH2	7.07e-06	2	93	2	30506321
Pubmed	Isocitrate dehydrogenase (IDH) status prediction in histopathology images of gliomas using deep learning.	IDH1 IDH2	7.07e-06	2	93	2	32382048
Pubmed	Estimation of the occurrence rates of IDH1 and IDH2 mutations in gliomas and the reconsideration of IDH-wildtype anaplastic astrocytomas: an institutional experience.	IDH1 IDH2	7.07e-06	2	93	2	34162262
Pubmed	Genetic variations in IDH gene as prognosis predictors in TACE-treated hepatocellular carcinoma patients.	IDH1 IDH2	7.07e-06	2	93	2	25355558
Pubmed	PCR-Based Simple Subgrouping Is Validated for Classification of Gliomas and Defines Negative Prognostic Copy Number Aberrations in IDH Mutant Gliomas.	IDH1 IDH2	7.07e-06	2	93	2	26558387
Pubmed	Differential prognostic impact of IDH1 and IDH2 mutations in chronic myelomonocytic leukemia.	IDH1 IDH2	7.07e-06	2	93	2	35351982
Pubmed	Intrahepatic cholangiocarcinomas with IDH1/2 mutation-associated hypermethylation at selective genes and their clinicopathological features.	IDH1 IDH2	7.07e-06	2	93	2	32978444
Pubmed	Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.	IDH1 IDH2	7.07e-06	2	93	2	28297679
Pubmed	Mutations of IDH1 and IDH2 are not detected in brain metastases of colorectal cancer.	IDH1 IDH2	7.07e-06	2	93	2	19350208
Pubmed	Isocitrate dehydrogenase mutations in gliomas: mechanisms, biomarkers and therapeutic target.	IDH1 IDH2	7.07e-06	2	93	2	22002076
Pubmed	IDH1 and IDH2 mutations are rare in pediatric myeloid malignancies.	IDH1 IDH2	7.07e-06	2	93	2	21233841
Pubmed	Adverse impact of IDH1 and IDH2 mutations in primary AML: experience of the Spanish CETLAM group.	IDH1 IDH2	7.07e-06	2	93	2	22520341
Pubmed	IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas.	IDH1 IDH2	7.07e-06	2	93	2	20975057
Pubmed	[IDH1- and IDH2-mutations in brain glial tumors - the new antioncogenic mechanism].	IDH1 IDH2	7.07e-06	2	93	2	29863707
Pubmed	Elevation of Urinary 2-Hydroxyglutarate in IDH-Mutant Glioma.	IDH1 IDH2	7.07e-06	2	93	2	26834160
Pubmed	Acute myeloid leukemia with isolated del(5q) is associated with IDH1/IDH2 mutations and better prognosis when compared to acute myeloid leukemia with complex karyotype including del(5q).	IDH1 IDH2	7.07e-06	2	93	2	31685963
Pubmed	NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity.	CIITA NLRC5	7.07e-06	2	93	2	37108368
Pubmed	IDH1/2 but not DNMT3A mutations are suitable targets for minimal residual disease monitoring in acute myeloid leukemia patients: a study by the Acute Leukemia French Association.	IDH1 IDH2	7.07e-06	2	93	2	26486081
Pubmed	IDH1 and IDH2 mutations in tumorigenesis: mechanistic insights and clinical perspectives.	IDH1 IDH2	7.07e-06	2	93	2	23071358
Pubmed	Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.	IDH1 IDH2	7.07e-06	2	93	2	19554337
Pubmed	IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours.	IDH1 IDH2	7.07e-06	2	93	2	21598255
Pubmed	Multimodal MRI features predict isocitrate dehydrogenase genotype in high-grade gliomas.	IDH1 IDH2	7.07e-06	2	93	2	27353503
Pubmed	Reprogramming of Isocitrate Dehydrogenases Expression and Activity by the Androgen Receptor in Prostate Cancer.	IDH1 IDH2	7.07e-06	2	93	2	31068457
Pubmed	A low-frequency variant at 8q24.21 is strongly associated with risk of oligodendroglial tumors and astrocytomas with IDH1 or IDH2 mutation.	IDH1 IDH2	7.07e-06	2	93	2	22922872
Pubmed	Isocitrate Dehydrogenase Mutations Confer Dasatinib Hypersensitivity and SRC Dependence in Intrahepatic Cholangiocarcinoma.	IDH1 IDH2	7.07e-06	2	93	2	27231123
Pubmed	IDH Mutations in AML Patients; A higher Association with Intermediate Risk Cytogenetics.	IDH1 IDH2	7.07e-06	2	93	2	32212799
Pubmed	IDH mutations occur frequently in Chinese glioma patients and predict longer survival but not response to concomitant chemoradiotherapy in anaplastic gliomas.	IDH1 IDH2	7.07e-06	2	93	2	21874255
Pubmed	IDH1 and IDH2 mutations in myelodysplastic syndromes and role in disease progression.	IDH1 IDH2	7.07e-06	2	93	2	26228814
Pubmed	Noninvasive Quantification of 2-Hydroxyglutarate in Human Gliomas with IDH1 and IDH2 Mutations.	IDH1 IDH2	7.07e-06	2	93	2	26669865
Pubmed	Co-deletion of chromosome 1p/19q and IDH1/2 mutation in glioma subsets of brain tumors in Chinese patients.	IDH1 IDH2	7.07e-06	2	93	2	22427879
Pubmed	Identification of additional IDH mutations associated with oncometabolite R(-)-2-hydroxyglutarate production.	IDH1 IDH2	7.07e-06	2	93	2	21996744
Pubmed	Impact of IDH1 and IDH2 mutation detection at diagnosis and in remission in patients with AML receiving allogeneic transplantation.	IDH1 IDH2	7.07e-06	2	93	2	35381077
Pubmed	IDH mutation analysis in gliomas as a diagnostic and prognostic biomarker.	IDH1 IDH2	7.07e-06	2	93	2	23451940
Pubmed	Frequent mutation of isocitrate dehydrogenase (IDH)1 and IDH2 in cholangiocarcinoma identified through broad-based tumor genotyping.	IDH1 IDH2	7.07e-06	2	93	2	22180306
Pubmed	Differential isocitrate dehydrogenase 1 and isocitrate dehydrogenase 2 mutation-related landscape in intrahepatic cholangiocarcinoma.	IDH1 IDH2	7.07e-06	2	93	2	38842680
Pubmed	IDH1/2 Mutations in Patients With Diffuse Gliomas: A Single Centre Retrospective Massively Parallel Sequencing Analysis.	IDH1 IDH2	7.07e-06	2	93	2	35262523
Pubmed	Frequent IDH1/2 mutations in intracranial chondrosarcoma: a possible diagnostic clue for its differentiation from chordoma.	IDH1 IDH2	7.07e-06	2	93	2	22323113
Pubmed	A nonsense mutation of IDH1 in myelodysplastic syndromes and related disorders.	IDH1 IDH2	7.07e-06	2	93	2	20962861
Pubmed	Diagnostic utility of IDH1/2 mutations to distinguish dedifferentiated chondrosarcoma from undifferentiated pleomorphic sarcoma of bone.	IDH1 IDH2	7.07e-06	2	93	2	28552826
Pubmed	Meta-analysis of whole-genome gene expression datasets assessing the effects of IDH1 and IDH2 mutations in isogenic disease models.	IDH1 IDH2	7.07e-06	2	93	2	34997121
Pubmed	The oncometabolite D-2-hydroxyglutarate induced by mutant IDH1 or -2 blocks osteoblast differentiation in vitro and in vivo.	IDH1 IDH2	7.07e-06	2	93	2	26046462
Interaction	PCDHGA4 interactions	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA8	3.56e-07	34	88	5	int:PCDHGA4
Interaction	H2BC5 interactions	IGSF8 PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 DPPA2 REPIN1 PCDHGA8	1.81e-06	331	88	10	int:H2BC5
Interaction	PCDHGA9 interactions	PCDHGA12 PCDHGA5 PCDHGA3 PCDHGA8	1.26e-05	33	88	4	int:PCDHGA9
Cytoband	5q31	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	4.08e-09	115	93	7	5q31
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	2.66e-06	298	93	7	chr5q31
Cytoband	19q13.33	PTOV1 GPR32 GPR32P1 C5AR2	6.69e-05	106	93	4	19q13.33
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	CA11 PTOV1 SPTBN4 IL11 PLA2G4C GPR32 GPR32P1 FFAR1 C5AR2 NFKBID	1.54e-04	1192	93	10	chr19q13
Cytoband	Ensembl 112 genes in cytogenetic band chr9q34	COL5A1 SLC2A6 FAM157B LAMC3 NAIF1	5.39e-04	325	93	5	chr9q34
Cytoband	16p12.3	ITPRIPL2 DCUN1D3	2.18e-03	34	93	2	16p12.3
Cytoband	Ensembl 112 genes in cytogenetic band chr7q36	DYNC2I1 REPIN1 C7orf33	4.21e-03	159	93	3	chr7q36
GeneFamily	Clustered protocadherins	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	2.35e-09	64	63	7	20
GeneFamily	NLR family	NOD1 CIITA NLRC5	8.78e-05	25	63	3	666
GeneFamily	Gla domain containing	F9 PROS1	9.09e-04	13	63	2	1250
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTOV1 B3GALT2 DYNC2I1 IDH2 FITM1 REPIN1 PLD4	8.87e-08	176	93	7	d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCell	facs-GAT-Fat-18m-Myeloid-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 CIITA SLC2A6 NFKBID ARHGAP30 PLD4	1.49e-06	169	93	6	7a7416fcbffcf57d19b477d9da091e04e3499524
ToppCell	facs-GAT-Fat-18m-Myeloid\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 CIITA SLC2A6 NFKBID ARHGAP30 PLD4	1.49e-06	169	93	6	0e1a99cd77edcf32bcb513abd247b2b27409ac63
ToppCell	facs-GAT-Fat-18m-Myeloid-myeloid_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 CIITA SLC2A6 NFKBID ARHGAP30 PLD4	1.49e-06	169	93	6	9bbad31ef03078f5aa456f2e1b17b49c91545ff0
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTOV1 B3GALT2 DYNC2I1 IDH2 FITM1 REPIN1	1.77e-06	174	93	6	a9f34d1237f335d27c5560ff514368f4709f9144
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-CD45\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 CIITA BAZ1A NFKBID ARHGAP30 PLD4	1.83e-06	175	93	6	16cf0c5d3d009480e07e8fe78c0f8555c2d6e3df
ToppCell	droplet-Kidney-nan-21m-Lymphocytic\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIITA BAZ1A NFKBID ARHGAP30 PLD4 SP140	2.09e-06	179	93	6	21736ae288ea6113e2a5604fbda338fc6b2b94a8
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF MCTP1 PLA2G4C CIITA PARVB CEMIP2	2.52e-06	185	93	6	808d5e880069aff8866cd2c733b9fe568a37701f
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MCTP1 LPAR5 CIITA C5AR2 NFKBID PLD4	2.69e-06	187	93	6	39b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CIITA NFKBID NLRC5 ARHGAP30 PLD4 SP140	2.86e-06	189	93	6	a12ca69eebc88725272c89d71a57fc6ce0c06813
ToppCell	PND07-Immune-Immune_Myeloid-DC-cDC2\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CIITA CYB561D1 ARHGAP30 F9 PLD4	1.53e-05	149	93	5	32e0be7da42d26956683b21a1e7ae6915e4c16fb
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-cDC1\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MCTP1 CIITA NFKBID ARHGAP30 SP140	1.58e-05	150	93	5	3dc23a37dbeb7f9df93683702a7838f7cc3ec9cc
ToppCell	PND03-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCTP1 LPAR5 CIITA CHD5 GNB1L	1.91e-05	156	93	5	af47a4b17342bdb3cb62d7e2d52a81168e588629
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VWF MCTP1 RP1L1 PARVB CEMIP2	2.57e-05	166	93	5	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	droplet-Lung-21m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FAM234B CIITA SLC2A6 NFKBID PLD4	2.65e-05	167	93	5	9526e2c7673d569d04e0728a2526318e67432e0a
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GREB1L VWF PIEZO1 C5AR2 CEMIP2	2.73e-05	168	93	5	06dc5b2d356d3a9454b10bba6f3b9ead2a0a7d46
ToppCell	facs-Heart-RA-18m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GREB1L VWF PIEZO1 C5AR2 CEMIP2	2.73e-05	168	93	5	1002f058a340763e3d8de0bd1f0547a903526ec6
ToppCell	droplet-Kidney-nan-21m-Lymphocytic-CD45____B_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIITA BAZ1A NFKBID PLD4 SP140	2.80e-05	169	93	5	d44fc49056799dfc70a3c7d538c210d88ffded05
ToppCell	356C-Myeloid-Monocyte-CD16+_Monocyte\|Monocyte / Donor, Lineage, Cell class and subclass (all cells)	DUOX1 LPAR5 HAGHL NAIF1 WARS2	3.05e-05	172	93	5	9dca1542145d88559527db7e0f6ad150df59ca2d
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-lymphocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 CIITA NFKBID ARHGAP30 PLD4	3.05e-05	172	93	5	e680abead2da75e50774da02384eb2729c839c01
ToppCell	facs-Trachea-18m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_tracheal_l15\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CIITA SLC2A6 ARHGAP30 PLD4 SP140	3.05e-05	172	93	5	eaba10a4d4eaab42ad2e2da65ebb20b50edaf815
ToppCell	15-Airway-Immune-Hematopoietic,_B_Cells\|Airway / Age, Tissue, Lineage and Cell class	CIITA NLRC5 ARHGAP30 PLD4 SP140	3.05e-05	172	93	5	36f2444754f1e37683cb812380e6b05b356f9f4a
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Pre-B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CIITA NFKBID NLRC5 PLD4 SP140	3.14e-05	173	93	5	67c342295b8a06ce38e081ba74478c568917a396
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Myeloid-microglial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA2 C5AR2 OTOP1 ARHGAP30 PLD4	3.22e-05	174	93	5	8d6df5938cef542f23259ce471eea1a1afbed03c
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA2 C5AR2 OTOP1 ARHGAP30 PLD4	3.22e-05	174	93	5	2af54c3427aacfa232e2aca6003b4a8ecb8bba66
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCDHGA2 C5AR2 OTOP1 ARHGAP30 PLD4	3.22e-05	174	93	5	eca643b8f5b92aeed5a77c94b4301fd8100f9401
ToppCell	droplet-Kidney-nan-21m-Epithelial-Pecam____Kidney_cortex_artery_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF PCDHGA12 MYO1H LAMC3 EGFLAM	3.69e-05	179	93	5	b7281160c84dd053a2981c9c76ea6cc6d2592cd5
ToppCell	18-Airway-Immune-Hematopoietic,_B_Cells\|Airway / Age, Tissue, Lineage and Cell class	LPAR5 SLC2A6 NFKBID ARHGAP30 PLD4	3.79e-05	180	93	5	200cecbd8c12a4ec334583fdd5057397504de71e
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PCDHGA7 PCDHGA3 PCDHGA1 F9	3.82e-05	90	93	4	3817a5b0235e632d976ea565175bdbebbd959bf0
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	PCDHGA7 PCDHGA3 PCDHGA1 F9	3.82e-05	90	93	4	a528f5dcee1a356dea89ff2588d2e0f276f2d5fc
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Immature_B\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CIITA NFKBID ARHGAP30 PLD4 SP140	3.89e-05	181	93	5	51836cdc66e42f04ed6a3c167cd6a3a67428c9f7
ToppCell	facs-Aorta-Heart-3m-Myeloid-macrophage\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LPAR5 CIITA SLC2A6 ARHGAP30 PLD4	3.99e-05	182	93	5	df26388c0c46d1c4775103c8e802937b4d4e7470
ToppCell	3'-Adult-LargeIntestine-Epithelial-Tuft-related-Microfold_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ST6GALNAC1 COL11A2 IGFALS PLA2G4C SLC2A6	3.99e-05	182	93	5	b4f347fb684f6840c166d7473f3f56389f69c14b
ToppCell	droplet-Mammary_Gland-nan-21m-Lymphocytic-B_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIITA NFKBID ARHGAP30 PLD4 SP140	3.99e-05	182	93	5	97f393549c7718a32af55b2377801bfebb10cc52
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF MCTP1 WWP1 RP1L1 CEMIP2	4.10e-05	183	93	5	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	droplet-Mammary_Gland-nan-21m-Lymphocytic-B_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIITA NFKBID ARHGAP30 PLD4 SP140	4.10e-05	183	93	5	e7038532a6e159bb3e383cdd9c44b3b7f21c0c01
ToppCell	facs-Aorta-Heart-3m-Myeloid-leukocyte\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LPAR5 CIITA SLC2A6 ARHGAP30 PLD4	4.10e-05	183	93	5	062ec08d66c923f90fee771b1bf8d98bdc7e6c1b
ToppCell	droplet-Marrow-BM-1m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF8 IDH1 IDH2 PROS1 PLD4	4.54e-05	187	93	5	028e7d6e1211e123879d2f353dc32fae1185dd8e
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF MCTP1 PLA2G4C CIITA PARVB	4.54e-05	187	93	5	dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF MCTP1 WWP1 RP1L1 CEMIP2	4.54e-05	187	93	5	7170694a1b86fe8d84d96c880ffe57af09bdc026
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-Macrophages\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LPAR5 CIITA C5AR2 NFKBID PLD4	4.78e-05	189	93	5	b8cbfc47f3f40b6fccd15899d58c87d07b0001aa
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF MCTP1 WWP1 PARVB CEMIP2	4.90e-05	190	93	5	eae5bcdb8a35f3fba4d25854c1a43f83f80832a2
ToppCell	droplet-Marrow-nan-18m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF8 IDH1 IDH2 PROS1 PLD4	4.90e-05	190	93	5	95d8dc8488e95158e84a44bb53ea4ab7bf3d44bb
ToppCell	droplet-Marrow-nan-21m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF8 IDH1 IDH2 PROS1 PLD4	4.90e-05	190	93	5	6c6d3259e23ec90c08756f500ae8a7aff8b8a5b3
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWF MCTP1 WWP1 PARVB CEMIP2	4.90e-05	190	93	5	3346bfd0474828b3729cffa9f4cc57b04dd30443
ToppCell	droplet-Marrow-nan-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGSF8 IDH1 IDH2 PROS1 PLD4	4.90e-05	190	93	5	e2fdbfaf08da3274b6bdda615386aa880040a90a
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GALNAC1 VWF PARVB PCDHGA8 CEMIP2	5.02e-05	191	93	5	9fc674a58f20b47255e4457d5195c8cff17b0414
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF MCTP1 PLA2G4C CIITA PARVB	5.02e-05	191	93	5	a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-B_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CIITA HAGHL SLC2A6 PLD4 SP140	5.02e-05	191	93	5	31169e01072e5fea364178264a35754b6cf2c93b
ToppCell	droplet-Lung-LUNG-1m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST6GALNAC1 VWF PARVB PCDHGA8 CEMIP2	5.02e-05	191	93	5	c379a499dabf3c9ed80f47adbb2d949821c5b053
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_immature_monocyte1_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MCTP1 LPAR5 CIITA C5AR2 PLD4	5.02e-05	191	93	5	79c83a710aa17fc06f286e4ea2011ed9e30e3bc6
ToppCell	wk_08-11-Hematologic-Myeloid-CX3CR1+_Mac\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	MCTP1 LPAR5 CIITA ARHGAP30 PLD4	5.28e-05	193	93	5	afc20433b5abc9b430751a2aa8d93b0fd136a888
ToppCell	Fetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MCTP1 LPAR5 CIITA NFKBID PLD4	5.28e-05	193	93	5	2d0dd2671ff27b922eb316f1ed0140353536ef30
ToppCell	PCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MCTP1 LPAR5 CIITA ARHGAP30 PLD4	5.41e-05	194	93	5	846b4170544cdf58b536fb7a5fd34b79b0b17993
ToppCell	368C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	LPAR5 WWP1 OSBPL7 CEMIP2 PLD4	5.41e-05	194	93	5	58046894446cb250814252a23f60fdd59c114d77
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	VWF MCTP1 PLA2G4C CIITA PARVB	5.54e-05	195	93	5	56efeb58df19f357d7d5ce87348d4f196a595421
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_B-Memory_B_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	CIITA HAGHL SLC2A6 PLD4 SP140	5.54e-05	195	93	5	8b307079cee67fc1df55277d0cab21ea4b97e552
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MCTP1 LPAR5 CIITA C5AR2 IDH1	5.54e-05	195	93	5	312d9625655b38f1a7c2bf8f8bb7b667ebdf9617
ToppCell	PCW_10-12-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	MCTP1 LPAR5 CIITA FBXL14 PLD4	5.68e-05	196	93	5	ce3709adbde7559b40c964888935914f66003247
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_cell-B_naive\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CIITA PCDHGA1 NFKBID PARVB SP140	5.68e-05	196	93	5	de43dd0697e1daf4d50800957cf0b27b54a7a333
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_B\|lymph-node_spleen / Manually curated celltypes from each tissue	CIITA SLC2A6 NFKBID PLD4 SP140	5.82e-05	197	93	5	9837bd2cc28b79147fb5d1997631ef953fd020e4
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MCTP1 CIITA NFKBID ARHGAP30 SP140	5.82e-05	197	93	5	c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCell	mLN-(2)_B_cell-(22)_B_cell_memory\|mLN / shred on region, Cell_type, and subtype	CIITA HAGHL SLC2A6 PLD4 SP140	5.96e-05	198	93	5	4d189df1db5b41306e9653436d7d7e75ff5afa06
ToppCell	mLN-B_cell-B_cell_memory\|mLN / Region, Cell class and subclass	CIITA HAGHL SLC2A6 PLD4 SP140	5.96e-05	198	93	5	6dc155ee487abb1319a60a7a70e84c28c9851985
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MCTP1 CIITA NFKBID PARVB DCUN1D3	6.10e-05	199	93	5	54167894a16e975d0541cbe3e515bcfa183044f6
ToppCell	Parenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CIITA SLC2A6 NFKBID NLRC5 PARVB	6.10e-05	199	93	5	841338719d042247966867ac608146395eb8c4d9
ToppCell	COVID-19-lung\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DUOX1 CIITA BAZ1A NLRC5 CEMIP2	6.10e-05	199	93	5	155b03b859157013e9142e9248551369127d9204
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	SPTBN4 HAGHL CHD5 MDGA1 PLD4	6.25e-05	200	93	5	61d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	VWF MCTP1 PLA2G4C PARVB CEMIP2	6.25e-05	200	93	5	2d07237022b409c4fac6fcf99b68c8affb3007cd
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Interneuron\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	COL5A1 PIEZO1 CHD5 CYB561D1 PROS1	6.25e-05	200	93	5	a6500d0d2e8bcac92381ab771dbdee66b0e1d48e
ToppCell	(22)_B_cell_memory\|World / shred on Cell_type and subtype	CIITA HAGHL SLC2A6 PLD4 SP140	6.70e-05	203	93	5	94ac418c9bfef1ce2e000a9c4117485651dfe85a
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-B_activate-7\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CIITA FFAR1 NFKBID EGFLAM	1.69e-04	132	93	4	c07842a4b514f1e950c8af303f3b6b4275906e6a
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	EP400 CIITA GNB1L PLD4	1.79e-04	134	93	4	0e3f37ef041b751ed45060b5ce39385a2731370b
ToppCell	facs-Aorta-Heart-3m-Mesenchymal-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARHGAP30 FITM1 F9 PLD4	1.95e-04	137	93	4	587a369b148bb2600c06db39298feddfc99cb6ad
ToppCell	droplet-Pancreas-Exocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	C5AR2 NLRC5 ARHGAP30 PLD4	2.23e-04	142	93	4	bf4a9633d128805a0d7e426d6fe6c29db1ff8c81
ToppCell	PND07-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CIITA CYB561D1 F9 PLD4	2.36e-04	144	93	4	f5d0d0564fcbec8a5d87119e0807b619faa77b0f
ToppCell	COVID-19_Severe-MAIT\|World / disease group, cell group and cell class	GABRG2 PCDHGA5 FITM1 DCUN1D3	2.42e-04	145	93	4	8d63f97812f63329ef9c940b291dc5a1c4d90690
ToppCell	droplet-Pancreas-Exocrine-18m-Hematologic\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIITA C5AR2 NLRC5 ARHGAP30	2.55e-04	147	93	4	684e2d8d2f0516cf8b0dc53efa7efc3050bbf0d1
ToppCell	Bronchus_Control_(B.)-Immune-TX-TRAM-3\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	GREB1L FFAR1 C1orf167 SP140	2.55e-04	147	93	4	50a855aa7f214c3be8ac46a22adf9bc9dd0285db
ToppCell	droplet-Pancreas-Exocrine-18m-Hematologic-leukocyte\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CIITA C5AR2 NLRC5 ARHGAP30	2.55e-04	147	93	4	c031fad0a4e192019775809968e46da54a111d27
ToppCell	COVID-19_Severe-MAIT\|COVID-19_Severe / disease group, cell group and cell class	GABRG2 PCDHGA5 FITM1 DCUN1D3	2.75e-04	150	93	4	923ea7ecc0aa05fb0396082cd9c3d1594135f1e0
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-9\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CIITA FFAR1 PCDHGA1 NFKBID	2.75e-04	150	93	4	d9931507257c64ead4a53786e6822f51962c6015
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCTP1 BAZ1A ARHGAP30 SP140	2.97e-04	153	93	4	6a2a2379238133ce0ad714af130ffe02dd317247
ToppCell	E16.5-Immune-Immune_Myeloid-Granulocytic-Neutrophil\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCTP1 BAZ1A ARHGAP30 SP140	2.97e-04	153	93	4	faa442dd925b2b09919e93c492ccc3f19803ad24
ToppCell	tumor_Lymph_Node_/_Brain-B_lymphocytes-Undetermined\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	LPAR5 NFKBID ARHGAP30 SP140	3.04e-04	154	93	4	e16f200391537aa1002b0079481b94e1fb86b9ad
ToppCell	PND07-Immune-Immune_Myeloid-DC-cDC2-cDC2_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CIITA CYB561D1 ARHGAP30 PLD4	3.04e-04	154	93	4	e3a8a1e63ab345de62bd2e5e54342b00f04ae422
ToppCell	Striatum-Hematopoietic\|Striatum / BrainAtlas - Mouse McCarroll V32	C5AR2 NLRC5 ARHGAP30 PLD4	3.12e-04	155	93	4	12301d823338bf829475905c66c5f08f7159d29f
ToppCell	PND14-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	IGSF8 BAZ1A ARHGAP30 PLD4	3.19e-04	156	93	4	8349604bd801e20d33770f7d8243598c3756302b
ToppCell	facs-Marrow-B-cells-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC2A6 PCDHGA3 PROS1 PLD4	3.27e-04	157	93	4	0966e347f8d32b13f8a3b3afba3f64637c69cdf9
ToppCell	facs-Marrow-B-cells-24m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC2A6 PCDHGA3 PROS1 PLD4	3.27e-04	157	93	4	6ebfedd91d62c6d4aa8f046657a899a279f82ba2
ToppCell	facs-Heart-RV-24m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IGFALS PLIN5 IDH2 NMB	3.35e-04	158	93	4	2ef43d14ee65d004dc62c12ff209bbe12e4db681
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL11 PLIN5 CYB561D1 PCDHGA8	3.35e-04	158	93	4	6d2709b387945c015faa223c20d22b52a4082140
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 SLC2A6 ARHGAP30 PLD4	3.35e-04	158	93	4	bd37d567754b660bfff7aef81cb307a384ec20a0
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 CIITA ARHGAP30 SP140	3.35e-04	158	93	4	90ca742739a208d457db087655ba3d1c18a9da57
ToppCell	droplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPTBN4 COL11A2 CIITA PLD4	3.35e-04	158	93	4	9a6d9b541446a6aa9f8ed040b330dbb5c6447076
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A2 SLC2A6 IDH1 PLD4	3.35e-04	158	93	4	ad1040bce6ad655c2502d9abb02507ecff177f83
ToppCell	droplet-Lung-3m-Hematologic-myeloid-interstitial_macrophage-interstitial_macrophage_l12\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SPTBN4 COL11A2 CIITA PLD4	3.35e-04	158	93	4	2438713d2a7e32c647ab3384237ed614f4ec8fec
ToppCell	facs-Lung-Endomucin_-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A2 SLC2A6 IDH1 PLD4	3.35e-04	158	93	4	ac7aef01eda1dca80d6c5b508649fcad55803a67
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCTP1 CIITA ARHGAP30 SP140	3.52e-04	160	93	4	8dae9b0cf90a09acb196223f45a14680102630b2
ToppCell	Adult-Mesenchymal-myofibroblast_cell-D175\|Adult / Lineage, Cell type, age group and donor	GREB1L SPTBN4 MYO1H EGFLAM	3.60e-04	161	93	4	048b7dc00746987a24bf870d4d278c4183eb04a2
Disease	Sarcosine measurement	PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	4.98e-11	23	86	6	EFO_0021668
Disease	mental development measurement	PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	8.69e-11	25	86	6	EFO_0008230
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PCDHGA8	1.59e-09	71	86	7	EFO_0007878, EFO_0007979
Disease	hepatocellular clear cell carcinoma (is_implicated_in)	IDH1 IDH2	8.40e-06	2	86	2	DOID:5016 (is_implicated_in)
Disease	Enchondroma	IDH1 IDH2	8.40e-06	2	86	2	C1704356
Disease	Chondroma	IDH1 IDH2	8.40e-06	2	86	2	C0936248
Disease	Maffucci Syndrome	IDH1 IDH2	2.51e-05	3	86	2	C0024454
Disease	Chorioangioma	IDH1 IDH2	5.02e-05	4	86	2	C0677608
Disease	Angioma	IDH1 IDH2	5.02e-05	4	86	2	C1959588
Disease	Enchondromatosis	IDH1 IDH2	5.02e-05	4	86	2	C0014084
Disease	Hemangioma	IDH1 IDH2	5.02e-05	4	86	2	C0018916
Disease	Hemangioma, Intramuscular	IDH1 IDH2	5.02e-05	4	86	2	C0205789
Disease	Histiocytoid hemangioma	IDH1 IDH2	5.02e-05	4	86	2	C0205788
Disease	Biliary Tract Neoplasm	IDH1 IDH2	1.25e-04	6	86	2	C0005426
Disease	Childhood Oligodendroglioma	IDH1 IDH2	1.75e-04	7	86	2	C0280475
Disease	Adult Oligodendroglioma	IDH1 IDH2	1.75e-04	7	86	2	C0279070
Disease	Oligodendroblastoma	IDH1 IDH2	1.75e-04	7	86	2	C0344461
Disease	Mixed Oligodendroglioma-Astrocytoma	IDH1 IDH2	1.75e-04	7	86	2	C0280793
Disease	Mixed Oligodendroglioma-Ependymoma	IDH1 IDH2	1.75e-04	7	86	2	C0751395
Disease	Well Differentiated Oligodendroglioma	IDH1 IDH2	1.75e-04	7	86	2	C0751396
Disease	oligodendroglioma	IDH1 IDH2	2.32e-04	8	86	2	C0028945
Disease	Anaplastic Oligodendroglioma	IDH1 IDH2	2.32e-04	8	86	2	C0334590
Disease	Thrombus	VWF F9 PROS1	3.31e-04	46	86	3	C0087086
Disease	Thrombosis	VWF F9 PROS1	4.00e-04	49	86	3	C0040053
Disease	Hematologic Neoplasms	IDH1 IDH2	5.44e-04	12	86	2	C0376545
Disease	lymphocyte count	CA11 PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 PIEZO1 OSBPL7 NLRC5 PCDHGA8 SP140	1.08e-03	1464	86	12	EFO_0004587
Disease	Dyschondroplasias	IDH1 IDH2	1.39e-03	19	86	2	C0013366
Disease	Liver Cirrhosis, Experimental	COL5A1 VWF IGFALS NLRC5 ARHGAP30 CEMIP2 PLD4 SP140	1.90e-03	774	86	8	C0023893
Disease	Intrahepatic Cholangiocarcinoma	IDH1 IDH2	2.22e-03	24	86	2	C0345905
Disease	Extrahepatic Cholangiocarcinoma	IDH1 IDH2	2.22e-03	24	86	2	C3805278
Disease	Cholangiocarcinoma	IDH1 IDH2	2.61e-03	26	86	2	C0206698
Disease	Anaplastic astrocytoma	IDH1 IDH2	2.81e-03	27	86	2	C0334579
Disease	mean platelet volume	VWF PCDHGA12 PCDHGA7 PCDHGA5 PCDHGA3 PCDHGA2 PCDHGA1 DYNC2I1 PCDHGA8	2.89e-03	1020	86	9	EFO_0004584

Protein segments in the cluster

Peptide	Gene	Start	Entry
VHQRIAELRKAGLWS	EP400	781	Q96L91
AAAAVALGRWQLLRK	C1orf167	531	Q5SNV9
RKARIRLHWAGQTLA	CYB561D1	86	Q8N8Q1
TLGNWHELRVSRTAK	EGFLAM	691	Q63HQ2
AFNSHWLVRDLRGKS	CHD5	1446	Q8TDI0
AKLAWELGRRHQSTL	CIITA	661	P33076
ARIVSGSHDRTLKLW	ATG16L1	421	Q676U5
AHLIRAKLLREGWVH	GPR32	236	O75388
KALRWLDLSHNRVAG	IGFALS	266	P35858
RALVLWAALGAAAHI	CA11	11	O75493
GRALLTQHKIRTWEG	APEX2	131	Q9UBZ4
IDLRLSGRAVAVWVH	C7orf33	36	Q8WU49
IARRALRFVLSKHWG	C5orf38	61	Q86SI9
GQRSLHREIAIALWK	DCUN1D3	196	Q8IWE4
GAIKVTDRHIWRSAL	BAZ1A	996	Q9NRL2
LRRWHKSRLLQASEG	PCDHGA7	716	Q9Y5G6
LRRWHKSRLLQASGG	PCDHGA2	716	Q9Y5H1
HVRAKLSWAKARPLS	HAGHL	191	Q6PII5
LRRWHKSRLLQAEGS	PCDHGA5	716	Q9Y5G8
LRRWHKSRLLQDSGG	PCDHGA8	716	Q9Y5G5
LRRWHKSRLLQASGG	PCDHGA12	716	O60330
EHRWGSKGSRLQRLV	DUOX1	41	Q9NRD9
LVRSRNKGALDTHAW	MDGA1	851	Q8NFP4
KILATAGWDHRIRVF	GNB1L	266	Q9BYB4
LHRKSHLWRGIVSIT	MCTP1	461	Q6DN14
ALALWVFLRALRVHS	LPAR5	41	Q9H1C0
LAAKSAAWHGILRRV	NAIF1	41	Q69YI7
TLLHLFAARGLRWAA	NFKBID	51	Q8NI38
HGFRLLWIDTKIAAR	LETM1	166	O95202
ASGSIDIQHLKRRWA	DYNC2I1	1026	Q8WVS4
RWDISRALGVAKLFH	MFSD6L	6	Q8IWD5
RHVQWLRRAGGSSLK	IL11	106	P20809
TQARLTKEHRWGSAL	PEX5L	241	Q8IYB4
HPAALVVSKLSLRWA	FAM234B	571	A2RU67
WGRVFHKGRSALVLQ	F9	356	P00740
GLSLADGKWHRVAVA	COL11A2	141	P13942
KRKALWAHLFSSLRG	NOD1	616	Q9Y239
LAHVGAKERELSWRN	LRATD2	186	Q96KN1
AVRLSELGWLHNKIR	TUBGCP3	291	Q96CW5
HKSVWRGVEAKLHLR	FBXL14	41	Q8N1E6
LRALAWLRGTDVDVH	SLC2A6	231	Q9UGQ3
VATHFVARLKSWRGN	GREB1L	1001	Q9C091
RWVQRTKARLGLSDH	NLRC5	546	Q86WI3
HRLSNKLLAWSGVLE	PTOV1	86	Q86YD1
ALRWSVDSIHGKNLV	PARVB	166	Q9HBI1
LRRWHKSRLLQASGG	PCDHGA3	716	Q9Y5H0
GRLTRGVLHSKFWVV	PLD4	206	Q96BZ4
LLLAWAVHAAGVSKS	OTOP1	76	Q7RTM1
WRRAVANAKSIGHLI	PLA2G4C	266	Q9UP65
WNAKRSLFRTHLIGV	B3GALT2	16	O43825
ATKRIWIHRRGEATA	FAM157B	166	P0CG42
ASIFAWTRGLAHRAK	IDH1	331	O75874
SIFAWTRGLEHRGKL	IDH2	371	P48735
GSWAQIAEKRAVLAH	IGSF8	281	Q969P0
HRRKLRAAWVAGGAL	FFAR1	216	O14842
RRVGATWLLHLAVAD	C5AR2	66	Q9P296
TARHLSRLVVGAAVW	FITM1	121	A5D6W6
AHLIRAKLLREGWVH	GPR32P1	236	Q8NGA4
GSHAAAKRWLGKLRR	CENPVL3	46	A0A0U1RRI6
IRSLKIELHSRSGHW	GDF11	221	O95390
KVLQSALAAIRHARW	ILF2	196	Q12905
TGAWRHGRIHIRIAK	GABRG2	426	P18507
ELHGARKASWTLLAR	CEMIP2	231	Q9UHN6
RGINLSDGKWHRIAL	COL5A1	156	P20908
VHGRLLSADTKGWVR	DPPA2	226	Q7Z7J5
VGRLRLAWVAHKTLT	TBRG4	26	Q969Z0
LSRSGRVLHRLFGKW	OSBPL7	691	Q9BZF2
VRKWRSIFNLGRSGH	ARHGAP30	286	Q7Z6I6
LRRWHKSRLLQASGG	PCDHGA1	716	Q9Y5H4
GHARELAAARLLSTW	ITPRIPL2	486	Q3MIP1
ALWIHNLRSRGKLAL	MRPL22	11	Q9NWU5
ERWSFIRALHKGSAA	WARS2	11	Q9UGM6
WGARARKLILASFAV	TMEM265	71	A0A087WTH1
ADLTLKHGWRTGAII	NT5DC3	396	Q86UY8
NRFLRSKTLDGAHWR	ST6GALNAC1	501	Q9NSC7
HSAWLLIALRGGKIE	PROS1	346	P07225
RGWVALVLHLRAHSA	REPIN1	126	Q9BWE0
CGVAWADARSLKRHV	ZBTB11	891	O95625
LGKALSVVWDRHLSI	VWF	966	P04275
AWILTSALRVGLARH	TRPM5	101	Q9NZQ8
AARKRWGLAQHVRCS	RP1L1	421	Q8IWN7
LAHLASAVAELRARW	RP1L1	1531	Q8IWN7
LVRHGASVNVADLWK	TNKS	736	O95271
SRASKIRVHSRGNLW	NMB	36	P08949
LIRRHEAFRKAAAAW	SPTBN4	2086	Q9H254
AVVARGTTILAKHAW	VAMP7	6	P51809
EGNIRSVKWRGHLIA	VPS41	171	P49754
KGGHARSKNWRLSVR	SP140	631	Q13342
GRRWSVELKRSVSHA	PLIN5	136	Q00G26
ARFRVTAHWLLVAAG	PIEZO1	186	Q92508
TAHWLLVAAGRVLAV	PIEZO1	191	Q92508
KGAKHLRVAARDLTW	UGT2B28	471	Q9BY64
QVWSHRTLKADALLG	WWP1	81	Q9H0M0
RFTVWLHGVLDKLRS	ZC3H14	61	Q6PJT7
KWSHLATEARALARS	LAMC3	1151	Q9Y6N6
AIKLEAHWRGALARK	MYO1H	731	Q8N1T3