Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent protein folding chaperone	HSPD1 HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	3.69e-06	40	118	5	GO:0140662
GeneOntologyMolecularFunction	CTP binding	HSP90AA1 HSP90AB1	3.46e-05	2	118	2	GO:0002135
GeneOntologyMolecularFunction	P-type manganese transporter activity	ATP2C1 ATP2C2	3.46e-05	2	118	2	GO:0140613
GeneOntologyMolecularFunction	ATP hydrolysis activity	HSPD1 DDX59 ATP2C1 CHD5 ATP2C2 ATP5F1A SMC1B HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	6.18e-05	441	118	11	GO:0016887
GeneOntologyMolecularFunction	protein folding chaperone	HSPD1 HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	7.21e-05	73	118	5	GO:0044183
GeneOntologyMolecularFunction	disordered domain specific binding	HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	8.12e-05	39	118	4	GO:0097718
GeneOntologyMolecularFunction	sulfonylurea receptor binding	HSP90AA1 HSP90AB1	1.03e-04	3	118	2	GO:0017098
GeneOntologyMolecularFunction	UTP binding	HSP90AA1 HSP90AB1	2.06e-04	4	118	2	GO:0002134
GeneOntologyMolecularFunction	ATP-dependent activity	HSPD1 DDX59 MYO1D ATP2C1 CHD5 ATP2C2 ATP5F1A SMC1B HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	2.82e-04	614	118	12	GO:0140657
GeneOntologyMolecularFunction	pyrimidine ribonucleotide binding	HSP90AA1 HSP90AB1	3.42e-04	5	118	2	GO:0032557
GeneOntologyMolecularFunction	dATP binding	HSP90AA1 HSP90AB1	3.42e-04	5	118	2	GO:0032564
GeneOntologyMolecularFunction	adenyl deoxyribonucleotide binding	HSP90AA1 HSP90AB1	5.11e-04	6	118	2	GO:0032558
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	HSPD1 HBS1L DDX59 ARL11 ATP2C1 CHD5 ATP2C2 ATP5F1A SMC1B HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	6.69e-04	775	118	13	GO:0017111
GeneOntologyMolecularFunction	purine deoxyribonucleotide binding	HSP90AA1 HSP90AB1	7.13e-04	7	118	2	GO:0032554
GeneOntologyMolecularFunction	unfolded protein binding	HSPD1 HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	9.15e-04	126	118	5	GO:0051082
GeneOntologyMolecularFunction	TPR domain binding	HSP90AA1 HSP90AB1	9.47e-04	8	118	2	GO:0030911
GeneOntologyMolecularFunction	double-stranded RNA binding	HSPD1 AGO2 RC3H1 HSP90AB1	1.18e-03	78	118	4	GO:0003725
GeneOntologyMolecularFunction	deoxyribonucleotide binding	HSP90AA1 HSP90AB1	1.21e-03	9	118	2	GO:0032552
GeneOntologyMolecularFunction	pyrophosphatase activity	HSPD1 HBS1L DDX59 ARL11 ATP2C1 CHD5 ATP2C2 ATP5F1A SMC1B HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	1.38e-03	839	118	13	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	HSPD1 HBS1L DDX59 ARL11 ATP2C1 CHD5 ATP2C2 ATP5F1A SMC1B HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	1.39e-03	840	118	13	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	HSPD1 HBS1L DDX59 ARL11 ATP2C1 CHD5 ATP2C2 ATP5F1A SMC1B HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	1.39e-03	840	118	13	GO:0016818
GeneOntologyMolecularFunction	manganese ion transmembrane transporter activity	ATP2C1 ATP2C2	1.51e-03	10	118	2	GO:0005384
GeneOntologyMolecularFunction	nitric-oxide synthase regulator activity	HSP90AA1 HSP90AB1	1.51e-03	10	118	2	GO:0030235
GeneOntologyMolecularFunction	histone deacetylase binding	YWHAB NACC2 CHD5 HSP90AA1 HSP90AB1	1.81e-03	147	118	5	GO:0042826
GeneOntologyMolecularFunction	P-type calcium transporter activity	ATP2C1 ATP2C2	1.84e-03	11	118	2	GO:0005388
GeneOntologyMolecularFunction	pyrimidine nucleotide binding	HSP90AA1 HSP90AB1	1.84e-03	11	118	2	GO:0019103
GeneOntologyMolecularFunction	enoyl-CoA hydratase activity	HACD3 ECHS1	2.20e-03	12	118	2	GO:0004300
GeneOntologyBiologicalProcess	purine ribonucleoside monophosphate metabolic process	GMPR2 NT5C1B LRGUK AK2 URAD	6.41e-06	48	113	5	GO:0009167
GeneOntologyBiologicalProcess	purine nucleoside monophosphate metabolic process	GMPR2 NT5C1B LRGUK AK2 URAD	8.67e-06	51	113	5	GO:0009126
GeneOntologyBiologicalProcess	ribonucleoside monophosphate metabolic process	GMPR2 NT5C1B LRGUK AK2 URAD	3.33e-05	67	113	5	GO:0009161
GeneOntologyBiologicalProcess	nucleobase-containing small molecule metabolic process	IDH1 GMPR2 CPS1 NT5C1B PARP10 LRGUK GUCA1A DLAT AK2 PC OGA URAD PYCR3 ATP5F1A	7.80e-05	767	113	14	GO:0055086
GeneOntologyBiologicalProcess	purine ribonucleoside monophosphate catabolic process	GMPR2 NT5C1B URAD	1.03e-04	17	113	3	GO:0009169
GeneOntologyBiologicalProcess	purine nucleoside monophosphate catabolic process	GMPR2 NT5C1B URAD	1.23e-04	18	113	3	GO:0009128
GeneOntologyBiologicalProcess	nucleoside monophosphate metabolic process	GMPR2 NT5C1B LRGUK AK2 URAD	1.23e-04	88	113	5	GO:0009123
GeneOntologyBiologicalProcess	purine nucleotide metabolic process	IDH1 GMPR2 NT5C1B PARP10 LRGUK GUCA1A DLAT AK2 PC OGA URAD ATP5F1A	1.50e-04	619	113	12	GO:0006163
GeneOntologyCellularComponent	secretory granule	HSPD1 SPATA31A7 CPA3 IDH1 CAV2 CREG1 TRIP11 SPATA31A5 F13A1 LRGUK ATP2C1 SPATA31A1 CEP131 FRMPD3 PCDH7 VPS13B HSP90AA1 HSP90AB1	1.51e-05	1014	118	18	GO:0030141
GeneOntologyCellularComponent	acrosomal vesicle	SPATA31A7 CAV2 TRIP11 SPATA31A5 LRGUK SPATA31A1 CEP131 VPS13B	2.25e-05	206	118	8	GO:0001669
GeneOntologyCellularComponent	secretory vesicle	HSPD1 SPATA31A7 CPA3 IDH1 CAV2 CREG1 TRIP11 SPATA31A5 F13A1 LRGUK ATP2C1 SPATA31A1 CEP131 FRMPD3 PCDH7 VPS13B STX6 HSP90AA1 HSP90AB1	6.87e-05	1246	118	19	GO:0099503
GeneOntologyCellularComponent	sperm plasma membrane	HSPD1 HSP90AA1 HSP90AB1	2.50e-04	22	118	3	GO:0097524
GeneOntologyCellularComponent	sperm mitochondrial sheath	AK2 HSP90AA1	6.51e-04	7	118	2	GO:0097226
Domain	P-type_ATPase_IIA_PMR1	ATP2C1 ATP2C2	3.56e-05	2	112	2	IPR006413
Domain	Heat_shock_protein_90_CS	HSP90AA1 HSP90AB1	1.07e-04	3	112	2	IPR019805
Domain	Hsp90_fam	HSP90AA1 HSP90AB1	2.12e-04	4	112	2	IPR001404
Domain	Hsp90_N	HSP90AA1 HSP90AB1	2.12e-04	4	112	2	IPR020575
Domain	HSP90	HSP90AA1 HSP90AB1	2.12e-04	4	112	2	PF00183
Domain	HSP90	HSP90AA1 HSP90AB1	2.12e-04	4	112	2	PS00298
Domain	Autophagy-rel_C	ATG2B VPS13B	3.52e-04	5	112	2	IPR015412
Domain	ATG_C	ATG2B VPS13B	3.52e-04	5	112	2	PF09333
Domain	CbamoylP_synth_lsu-like_ATP-bd	CPS1 PC	7.34e-04	7	112	2	IPR005479
Domain	BC-like_N	CPS1 PC	7.34e-04	7	112	2	IPR005481
Domain	CPSase_L_D2	CPS1 PC	7.34e-04	7	112	2	PF02786
Domain	Biotin_carb_N	CPS1 PC	7.34e-04	7	112	2	PF00289
Domain	IQ	MYO1D IQCN CEP131 CAMTA1	8.74e-04	71	112	4	PF00612
Domain	Chorein_N	ATG2B VPS13B	9.75e-04	8	112	2	PF12624
Domain	VPS13_N	ATG2B VPS13B	9.75e-04	8	112	2	IPR026854
Domain	Biotin_lipoyl	DLAT PC	1.25e-03	9	112	2	PF00364
Domain	IQ	MYO1D IQCN CEP131 CAMTA1	1.43e-03	81	112	4	SM00015
Domain	BIOTINYL_LIPOYL	DLAT PC	1.55e-03	10	112	2	PS50968
Domain	Biotin_lipoyl	DLAT PC	1.55e-03	10	112	2	IPR000089
Domain	-	KAT6A ELP3 OGA	1.76e-03	40	112	3	3.40.630.30
Domain	IQ_motif_EF-hand-BS	MYO1D IQCN CEP131 CAMTA1	2.11e-03	90	112	4	IPR000048
Domain	Single_hybrid_motif	DLAT PC	2.26e-03	12	112	2	IPR011053
Domain	DUF4599	SPATA31A7 SPATA31A5	2.26e-03	12	112	2	PF15371
Domain	DUF4599	SPATA31A7 SPATA31A5	2.26e-03	12	112	2	IPR027970
Domain	IQ	MYO1D IQCN CEP131 CAMTA1	2.37e-03	93	112	4	PS50096
Domain	Cyt_P450_E_grp-I	CYP11A1 CYP24A1 CYP20A1	2.48e-03	45	112	3	IPR002401
Domain	Acyl_CoA_acyltransferase	KAT6A ELP3 OGA	2.48e-03	45	112	3	IPR016181
Domain	FERM_M	PTPN13 TLN2 FRMPD3	2.64e-03	46	112	3	PF00373
Domain	-	CPS1 PC	2.66e-03	13	112	2	3.40.50.20
Domain	ATP_GRASP	CPS1 PC	3.09e-03	14	112	2	PS50975
Domain	ATP-grasp	CPS1 PC	3.09e-03	14	112	2	IPR011761
Domain	PreATP-grasp_dom	CPS1 PC	3.09e-03	14	112	2	IPR016185
Domain	FERM_central	PTPN13 TLN2 FRMPD3	3.16e-03	49	112	3	IPR019748
Domain	FERM_domain	PTPN13 TLN2 FRMPD3	3.16e-03	49	112	3	IPR000299
Domain	FERM_1	PTPN13 TLN2 FRMPD3	3.35e-03	50	112	3	PS00660
Domain	FERM_2	PTPN13 TLN2 FRMPD3	3.35e-03	50	112	3	PS00661
Domain	FERM_3	PTPN13 TLN2 FRMPD3	3.35e-03	50	112	3	PS50057
Domain	Band_41_domain	PTPN13 TLN2 FRMPD3	3.35e-03	50	112	3	IPR019749
Domain	B41	PTPN13 TLN2 FRMPD3	3.35e-03	50	112	3	SM00295
Domain	-	CPS1 PC	3.56e-03	15	112	2	3.30.1490.20
Domain	ATPase_P-typ_TM_dom	ATP2C1 ATP2C2	4.05e-03	16	112	2	IPR023298
Domain	-	ATP2C1 ATP2C2	4.05e-03	16	112	2	1.20.1110.10
Domain	ATPase_P-typ_cation-transptr_C	ATP2C1 ATP2C2	4.57e-03	17	112	2	IPR006068
Domain	Cation_ATPase_C	ATP2C1 ATP2C2	4.57e-03	17	112	2	PF00689
Domain	-	CYP11A1 CYP24A1 CYP20A1	5.10e-03	58	112	3	1.10.630.10
Domain	p450	CYP11A1 CYP24A1 CYP20A1	5.10e-03	58	112	3	PF00067
Domain	ATP_grasp_subdomain_1	CPS1 PC	5.12e-03	18	112	2	IPR013815
Domain	Cation_ATPase_N	ATP2C1 ATP2C2	5.12e-03	18	112	2	PF00690
Domain	-	CPS1 PC	5.12e-03	18	112	2	3.30.470.20
Domain	HATPase_c	HSP90AA1 HSP90AB1	5.12e-03	18	112	2	SM00387
Domain	Cation_ATPase_N	ATP2C1 ATP2C2	5.12e-03	18	112	2	SM00831
Domain	Cyt_P450	CYP11A1 CYP24A1 CYP20A1	5.60e-03	60	112	3	IPR001128
Domain	6-PGluconate_DH_C-like	HIBADH PYCR3	5.70e-03	19	112	2	IPR008927
Domain	HATPase_c	HSP90AA1 HSP90AB1	5.70e-03	19	112	2	PF02518
Domain	ATPase_P-typ_cation-transptr_N	ATP2C1 ATP2C2	5.70e-03	19	112	2	IPR004014
Pubmed	Rewiring of the Human Mitochondrial Interactome during Neuronal Reprogramming Reveals Regulators of the Respirasome and Neurogenesis.	HSPD1 HACD3 LAMA4 IDH1 CREG1 ECHS1 HIBADH YWHAB LRPPRC DLAT AK2 COA7 ATP5F1A NEK11 STX6 HSP90AA1 HSP90AB1	5.51e-09	859	118	17	31536960
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	HSPD1 HACD3 SYNE1 ECHS1 SNX19 ARMC1 AKAP12 CACTIN LRPPRC PTPN13 ERAP2 ARHGEF10 TMEM131L DLAT CEP131 OGA PCDH7 COA7 PYCR3 VPS13B FAM177A1	2.79e-08	1487	118	21	33957083
Pubmed	High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.	HSPD1 HBS1L AGO2 MYO1D RC3H1 LARP1 YWHAB LRPPRC PYCR3 EIF3M ATP5F1A HSP90AA1	7.38e-08	469	118	12	37314180
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	HSPD1 AGO2 HACD3 SYNE1 LARP1 IQCN IDH1 ECHS1 YWHAB LRPPRC AK2 PC ATP5F1A HSP90AA1 HSP90AB1	1.06e-07	807	118	15	30575818
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	HSPD1 HBS1L MYO1D HACD3 LARP1 RANBP6 ELP3 YWHAB LRPPRC SPIN1 DLAT PC PYCR3 EIF3M ATP5F1A HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	1.24e-07	1335	118	19	29229926
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	AGO2 HACD3 KAT6A HECTD4 LARP1 IQCN GRHL2 PARP10 LRPPRC SLC25A36 TNRC18 PTPN13 ATP2C1 NACC2 SPIN1 CAMTA1 FGGY EIF3M VPS13B NOTCH3	1.40e-07	1489	118	20	28611215
Pubmed	Mapping of the gene family for human heat-shock protein 90 alpha to chromosomes 1, 4, 11, and 14.	HSP90AA1 HSP90AA4P HSP90AA2P	1.52e-07	4	118	3	1740332
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	HSPD1 KAT6A ECHS1 LRPPRC CFAP54 DLAT AK2 ATP5F1A VPS13B HSP90AB1	2.09e-07	331	118	10	29199018
Pubmed	The HSP90 family of genes in the human genome: insights into their divergence and evolution.	HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	2.22e-07	16	118	4	16269234
Pubmed	Mitochondrial protein interactome elucidated by chemical cross-linking mass spectrometry.	HSPD1 CYP11A1 CPS1 ECHS1 HIBADH LRPPRC DLAT AK2 COA7 ATP5F1A	2.90e-07	343	118	10	28130547
Pubmed	Proteomic analysis of the mitochondrial glucocorticoid receptor interacting proteins reveals pyruvate dehydrogenase and mitochondrial 60 kDa heat shock protein as potent binding partners.	HSPD1 LRPPRC DLAT ATP5F1A HSP90AA1 HSP90AB1	4.09e-07	83	118	6	35124280
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	HSPD1 AGO2 MYO1D RC3H1 LARP1 LRPPRC PCDH7 HSP90AA1 HSP90AB1	4.34e-07	274	118	9	34244482
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	HSPD1 GPAA1 HACD3 CYP20A1 IDH1 GMPR2 ECHS1 HIBADH YWHAB TRIP11 F13A1 PARP10 LRPPRC DLAT AK2 PYCR3 ATP5F1A HSP90AA1 HSP90AB1	4.41e-07	1451	118	19	30550785
Pubmed	Defining the membrane proteome of NK cells.	HSPD1 HBS1L AGO2 GPAA1 CYP20A1 DGKA LARP1 YWHAB LRPPRC ATP2C1 CHD5 OGA MED13 ATP5F1A IL6ST HSP90AA1 HSP90AB1	4.49e-07	1168	118	17	19946888
Pubmed	Substrate and functional diversity of lysine acetylation revealed by a proteomics survey.	KAT6A CPS1 ECHS1 AK2 PC COA7 ATP5F1A HSP90AB1	4.96e-07	203	118	8	16916647
Pubmed	USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.	HSPD1 MYO1D HACD3 CPS1 LRPPRC ATP2C1 PC PYCR3 ATP5F1A HSP90AA1 HSP90AA2P HSP90AB1	5.38e-07	565	118	12	33567341
Pubmed	CDK7/GRP78 signaling axis contributes to tumor growth and metastasis in osteosarcoma.	HSPD1 ECHS1 HIBADH YWHAB LRPPRC PC PYCR3 ATP5F1A HSP90AA1 HSP90AA2P HSP90AB1	6.12e-07	468	118	11	36042349
Pubmed	Quantitative analysis of PPT1 interactome in human neuroblastoma cells.	HSPD1 AGO2 YWHAB LRPPRC DLAT ATP5F1A HSP90AA1 HSP90AB1	6.40e-07	210	118	8	26217791
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	HSPD1 ATG2B LARP1 IDH1 TRIP11 AKAP12 SCML2 PTPN13 AK2 TAF6 PC OGA ATP5F1A HSP90AA1 HSP90AB1	6.73e-07	934	118	15	33916271
Pubmed	The testis-specific VAD1.3/AEP1 interacts with β-actin and syntaxin 1 and directs peri-nuclear/Golgi expression with bipartite nucleus localization (BNL) sequence.	SPATA31A7 SPATA31A5 SPATA31A1	7.56e-07	6	118	3	20850414
Pubmed	Targeted disruption of the spermatid-specific gene Spata31 causes male infertility.	SPATA31A7 SPATA31A5 SPATA31A1	7.56e-07	6	118	3	25930072
Pubmed	Nutritional stress exacerbates hepatic steatosis induced by deletion of the histidine nucleotide-binding (Hint2) mitochondrial protein.	HSPD1 CPS1 PC ATP5F1A	8.78e-07	22	118	4	26767982
Pubmed	Analysis of proteins copurifying with the CD4/lck complex using one-dimensional polyacrylamide gel electrophoresis and mass spectrometry: comparison with affinity-tag based protein detection and evaluation of different solubilization methods.	HSPD1 LRPPRC ATP5F1A HSP90AA1 HSP90AB1	1.04e-06	53	118	5	15047060
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	SYNE1 LAMA4 CCDC141 TRIP11 AKAP12 LRPPRC MED13 IL6ST NOTCH3 HSP90AA1 HSP90AB1	1.10e-06	497	118	11	23414517
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	SPATA31A7 LARP1 YWHAB LRPPRC SPIN1 HSP90AA1 HSP90AB1	1.11e-06	156	118	7	22952844
Pubmed	mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.	HSPD1 MYO1D IDH1 YWHAB LRPPRC PC ATP5F1A HSP90AA1 HSP90AB1	1.27e-06	312	118	9	37120454
Pubmed	Messenger RNA expression of heat shock proteins (HSPs) during ocular development.	HSPD1 HSP90AA1 HSP90AB1	1.32e-06	7	118	3	8974842
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	HACD3 RANBP6 AKAP12 LRPPRC SPIN1 DLAT EIF3M ATP5F1A HSP90AA1 HSP90AB1	1.40e-06	408	118	10	33766124
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	HSPD1 ASRGL1 HACD3 ATG2B ECHS1 FABP7 LRPPRC TNRC18 ATP2C1 DLAT TLN2 CEP131 PC FAM177A1 HSP90AA1 HSP90AB1	1.60e-06	1139	118	16	36417873
Pubmed	Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.	HSPD1 CYP11A1 CYP24A1 ECHS1 HIBADH LRPPRC DLAT AK2 PC ATP5F1A HSP90AB1	2.54e-06	542	118	11	14651853
Pubmed	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	HSPD1 CYP11A1 CYP24A1 IDH1 CPS1 ECHS1 HIBADH ARMC1 LRPPRC SLC25A36 DLAT AK2 PC ATP5F1A	3.28e-06	926	118	14	20877624
Pubmed	Quantitative study of the interactome of PKCζ involved in the EGF-induced tumor cell chemotaxis.	RANBP6 PARD6B SPIN1 EIF3M ATP5F1A HSP90AA1 HSP90AB1	3.33e-06	184	118	7	23402259
Pubmed	ZFP36L2 is a cell cycle-regulated CCCH protein necessary for DNA lesion-induced S-phase arrest.	HSPD1 YWHAB LRRC9 LRPPRC ATP2C1 EIF3M HSP90AA1	3.97e-06	189	118	7	29449217
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	HBS1L ZNF473 DGKA BBS4 F13A1 AKAP12 SEPSECS SCML2 PTPN13 SPIN1 TMEM131L CRYBG1 CAMTA1 ATP5F1A VPS13B	4.18e-06	1084	118	15	11544199
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	HSPD1 SYNE1 LARP1 CPS1 CACTIN LRPPRC CHD5 TAF6 PC ATP5F1A HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	4.34e-06	949	118	14	36574265
Pubmed	BGL3 lncRNA mediates retention of the BRCA1/BARD1 complex at DNA damage sites.	HSPD1 PC ATP5F1A HSP90AA1 HSP90AB1	5.16e-06	73	118	5	32347575
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	HSPD1 HBS1L HACD3 ATG2B LARP1 AKAP12 LRPPRC PTPN13 PCDH7 ATP5F1A HSP90AA1 HSP90AB1	5.51e-06	708	118	12	39231216
Pubmed	Short-chain 3-hydroxyacyl-coenzyme A dehydrogenase associates with a protein super-complex integrating multiple metabolic pathways.	HSPD1 IDH1 CPS1 HIBADH DLAT ATP5F1A	6.20e-06	132	118	6	22496890
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	HSPD1 ASRGL1 AGO2 MYO1D HACD3 SYNE1 LARP1 ELP3 YWHAB TRIP11 LRPPRC DLAT TLN2 PC ATP5F1A HSP90AA1 HSP90AB1	6.93e-06	1431	118	17	37142655
Pubmed	Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.	HSPD1 CYP11A1 CYP24A1 RANBP6 CPS1 ECHS1 HIBADH ARMC1 LRPPRC SLC25A36 DLAT AK2 PC COA7 ATP5F1A	7.33e-06	1136	118	15	34800366
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	MKRN3 ZNF473 SYNE1 HECTD4 YWHAB TRIP11 PTPN13 ARHGEF10 DLAT TLN2 TAF6 PC MED13 ATP5F1A HSP90AA1 HSP90AB1	7.41e-06	1285	118	16	35914814
Pubmed	14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization.	YWHAB HSP90AA1 HSP90AB1	8.19e-06	12	118	3	20642453
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	HSPD1 LARP1 IDH1 ECHS1 YWHAB AKAP12 LRPPRC SPIN1 DLAT AK2 OGA PYCR3 ATP5F1A HSP90AA1 HSP90AB1	8.39e-06	1149	118	15	35446349
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	HSPD1 HBS1L LARP1 RANBP6 IDH1 GMPR2 ECHS1 ELP3 YWHAB AKAP12 ARHGEF10 OGA PYCR3 EIF3M HSP90AA1 HSP90AA4P HSP90AB1	8.61e-06	1455	118	17	22863883
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	HSPD1 CYP20A1 IDH1 YWHAB AKAP12 LRPPRC SLC25A36 DLAT PYCR3 EIF3M ATP5F1A HSP90AA1 HSP90AB1	9.40e-06	878	118	13	37223481
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	MKRN3 HSPD1 AGO2 RBM12B SYNE1 YWHAB TRIP11 ATP2C1 SPIN1 AK2 OGA EIF3M	1.04e-05	754	118	12	35906200
Pubmed	Expression of hsp90 and cyclin D1 in human breast cancer.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	10376793
Pubmed	Human coronavirus dependency on host heat shock protein 90 reveals an antiviral target.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	33179566
Pubmed	Secretory pathway Ca2+ -ATPases promote in vitro microcalcifications in breast cancer cells.	ATP2C1 ATP2C2	1.14e-05	2	118	2	28618103
Pubmed	Regulation of embryonic stem cell pluripotency by heat shock protein 90.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	22696450
Pubmed	Discovery and validation of small-molecule heat-shock protein 90 inhibitors through multimodality molecular imaging in living subjects.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	22895790
Pubmed	Hsp90 is cleaved by reactive oxygen species at a highly conserved N-terminal amino acid motif.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	22848402
Pubmed	Glioma cells with the IDH1 mutation modulate metabolic fractional flux through pyruvate carboxylase.	IDH1 PC	1.14e-05	2	118	2	25243911
Pubmed	Expression of Hsp90 chaperone [corrected] proteins in human tumor tissue.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	19576239
Pubmed	A mouse tumor-specific transplantation antigen is a heat shock-related protein.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	3458168
Pubmed	Mechanism of dimer formation of the 90-kDa heat-shock protein.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	7588731
Pubmed	Murine 86- and 84-kDa heat shock proteins, cDNA sequences, chromosome assignments, and evolutionary origins.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	2925609
Pubmed	Cochaperone activity of human butyrate-induced transcript 1 facilitates hepatitis C virus replication through an Hsp90-dependent pathway.	HACD3 HSP90AA1	1.14e-05	2	118	2	19656872
Pubmed	Heat-shock proteins, Hsp84 and Hsp86, of mice and men: two related genes encode formerly identified tumour-specific transplantation antigens.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	2469626
Pubmed	Cloning and analysis of a human 86-kDa heat-shock-protein-encoding gene.	HSP90AA1 HSP90AA2P	1.14e-05	2	118	2	2591742
Pubmed	HSP90 expression and early recurrence in gastroenteropancreatic neuroendocrine tumors: Potential for a novel therapeutic target.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	33080545
Pubmed	Circulating Hsp90 Isoform Levels in Overweight and Obese Children and the Relation to Nonalcoholic Fatty Liver Disease: Results from a Cross-Sectional Study.	HSP90AA2P HSP90AB1	1.14e-05	2	118	2	31885746
Pubmed	Heat shock protein 90 facilitates SARS-CoV-2 structural protein-mediated virion assembly and promotes virus-induced pyroptosis.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	37011862
Pubmed	Cell surface heparan sulfate proteoglycans are involved in the binding of Hsp90α and Hsp90β to the cell plasma membrane.	HSP90AA2P HSP90AB1	1.14e-05	2	118	2	26651243
Pubmed	Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	36270993
Pubmed	Hsp90 regulation of fibroblast activation in pulmonary fibrosis.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	28239659
Pubmed	Despite their structural similarities, the cytosolic isoforms of human Hsp90 show different behaviour in thermal unfolding due to their conformation: An FTIR study.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	37028636
Pubmed	Proliferation, migration, and resistance to oxidative and thermal stresses of HT1080 cells with knocked out genes encoding Hsp90α and Hsp90β.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	37406487
Pubmed	Expression and therapeutic relevance of heat-shock protein 90 in pancreatic endocrine tumors.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	22194440
Pubmed	Circadian expression of 86- and 84-kDa heat shock proteins in the mouse suprachiasmatic nucleus.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	18480550
Pubmed	Hsp90 regulates the function of argonaute 2 and its recruitment to stress granules and P-bodies.	AGO2 HSP90AA1	1.14e-05	2	118	2	19458189
Pubmed	Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	22841823
Pubmed	Dissection of the functional differences between human secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and 2 isoenzymes by steady-state and transient kinetic analyses.	ATP2C1 ATP2C2	1.14e-05	2	118	2	16332677
Pubmed	Substitution of only two residues of human Hsp90alpha causes impeded dimerization of Hsp90beta.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	18347946
Pubmed	Heat shock protein 90 overexpression independently predicts inferior disease-free survival with differential expression of the alpha and beta isoforms in gastrointestinal stromal tumors.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	19047110
Pubmed	Conserved conformational changes in the ATPase cycle of human Hsp90.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	18400751
Pubmed	Inhibition of RPE cell sterile inflammatory responses and endotoxin-induced uveitis by a cell-impermeable HSP90 inhibitor.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	22019372
Pubmed	Heat shock protein HSP86 expression during mouse embryo development, especially in the germ-line.	HSP90AA1 HSP90AB1	1.14e-05	2	118	2	12136260
Pubmed	HSP90 protein stabilizes unloaded argonaute complexes and microscopic P-bodies in human cells.	AGO2 HSP90AA1	1.14e-05	2	118	2	20237157
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	HSPD1 AGO2 RBM12B LARP1 YWHAB EIF3M ATP5F1A HSP90AA1	1.28e-05	315	118	8	26777405
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	AGO2 MYO1D ELP3 YWHAB SNX19 CACTIN PTPN13 AK2 CEP131 PC PCDH7 ATP5F1A HSP90AA1 HSP90AB1	1.34e-05	1049	118	14	27880917
Pubmed	Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.	HSPD1 HACD3 YWHAB LRPPRC TLN2 PYCR3 ATP5F1A HSP90AA1 HSP90AB1	1.35e-05	418	118	9	32552912
Pubmed	Identification of potential protein interactors of Lrrk2.	AGO2 HSP90AA1 HSP90AB1	1.68e-05	15	118	3	17400507
Pubmed	Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3.	HSPD1 IDH1 YWHAB AKAP12 SEPSECS ATP5F1A HSP90AA1 HSP90AB1	1.87e-05	332	118	8	30595499
Pubmed	NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.	HSPD1 SYNE1 CPS1 YWHAB LRPPRC PC ATP5F1A HSP90AA1	1.91e-05	333	118	8	32665550
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	HSPD1 LARP1 YWHAB LRPPRC SPIN1 DLAT PYCR3 ATP5F1A HSP90AA1 HSP90AB1	1.94e-05	551	118	10	34728620
Pubmed	The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.	HSPD1 AGO2 IDH1 ECHS1 HIBADH YWHAB DLAT ATP5F1A HSP90AA1 HSP90AB1	1.97e-05	552	118	10	36293380
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	AGO2 HACD3 RC3H1 LARP1 YWHAB CACTIN LRPPRC SPIN1 ATP5F1A HSP90AA1 HSP90AB1	2.07e-05	678	118	11	30209976
Pubmed	Reversible oxidation of phosphatase and tensin homolog (PTEN) alters its interactions with signaling and regulatory proteins.	HSPD1 MYO1D AKAP12 ATP5F1A HSP90AB1	2.18e-05	98	118	5	26561776
Pubmed	FAM46C and FNDC3A Are Multiple Myeloma Tumor Suppressors That Act in Concert to Impair Clearing of Protein Aggregates and Autophagy.	HSPD1 IDH1 LRPPRC AK2 EIF3M HSP90AA1 HSP90AB1	2.32e-05	248	118	7	32963011
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	HSPD1 HACD3 LRPPRC PC ATP5F1A HSP90AA1 HSP90AA2P HSP90AB1	2.40e-05	344	118	8	36282215
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	HSPD1 HBS1L DDX59 HACD3 LARP1 CPS1 ELP3 YWHAB LRPPRC DLAT AK2 PC EIF3M ATP5F1A HSP90AA1 HSP90AB1	2.42e-05	1415	118	16	28515276
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	AGO2 SYNE1 HECTD4 YWHAB TRIP11 AKAP12 LRPPRC ZKSCAN1 TLN2 CEP131 FRMPD3 HSP90AA1 HSP90AB1	2.48e-05	963	118	13	28671696
Pubmed	Interactome dynamics of RAF1-BRAF kinase monomers and dimers.	YWHAB HSP90AA1 HSP90AB1	2.50e-05	17	118	3	37045861
Pubmed	The nuclear localization pattern and interaction partners of GTF2IRD1 demonstrate a role in chromatin regulation.	BBS4 HTRA4 TRIP11 ATP2C1	2.57e-05	50	118	4	26275350
Pubmed	A mitochondrial SCF-FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease.	HSPD1 CPS1 HSP90AA1 HSP90AB1	2.78e-05	51	118	4	36896912
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	HSPD1 MYO1D HACD3 LARP1 YWHAB CACTIN TAF6 EIF3M ATP5F1A HSP90AA1 HSP90AB1	2.80e-05	701	118	11	30196744
Pubmed	KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.	HSPD1 LRPPRC ATP5F1A HSP90AA1 HSP90AB1	2.90e-05	104	118	5	36055981
Pubmed	Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction.	HSPD1 HSP90AA1 HSP90AB1	2.99e-05	18	118	3	38266827
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	HSPD1 YWHAB LRPPRC ATP5F1A HSP90AA1 HSP90AB1	3.08e-05	175	118	6	25756610
Interaction	EIF4B interactions	HSPD1 AGO2 RBM12B RC3H1 KAT6A LARP1 YWHAB KCNJ2 OGA PCDH7 EIF3M ATP5F1A HSP90AA1	5.60e-07	402	116	13	int:EIF4B
Interaction	RICTOR interactions	HSPD1 HBS1L ZNF473 MYO1D ATG2B IDH1 CPS1 YWHAB LRPPRC SPIN1 PC OGA ATP5F1A STX6 HSP90AA1 HSP90AA2P HSP90AB1	1.61e-06	759	116	17	int:RICTOR
Interaction	GLDC interactions	HSPD1 AGO2 MYO1D RC3H1 LARP1 LRPPRC PCDH7 PYCR3 ATP5F1A HSP90AA1 HSP90AB1	2.51e-06	321	116	11	int:GLDC
Interaction	ACADM interactions	HSPD1 ECHS1 HIBADH AKAP12 LRPPRC TNRC18 SCML2 ATP5F1A	6.10e-06	169	116	8	int:ACADM
Interaction	ATG16L1 interactions	HSPD1 MYO1D HACD3 ATG2B LARP1 RANBP6 CAV2 YWHAB TRIP11 PARP10 COLEC12 CACTIN PTPN13 CEP131 TAF6 EIF3M ATP5F1A STX6 HSP90AA1 HSP90AB1	9.76e-06	1161	116	20	int:ATG16L1
Interaction	ACAA2 interactions	HSPD1 CYP24A1 CPS1 ECHS1 HIBADH AK2 TAGLN ATP5F1A	1.73e-05	195	116	8	int:ACAA2
Interaction	PDK4 interactions	DLAT AK2 COA7 HSP90AA1 HSP90AB1	1.75e-05	56	116	5	int:PDK4
Interaction	DNAJC4 interactions	CACTIN LRPPRC DLAT CEP131 COA7	1.91e-05	57	116	5	int:DNAJC4
Interaction	STK35 interactions	AK2 HSP90AA1 HSP90AA4P HSP90AB1	2.54e-05	30	116	4	int:STK35
Interaction	LHPP interactions	CREG1 HSP90AA1 HSP90AA4P HSP90AB1	5.94e-05	37	116	4	int:LHPP
Interaction	AASS interactions	HSPD1 YWHAB LRPPRC HSP90AA1 HSP90AB1	6.80e-05	74	116	5	int:AASS
Interaction	BGLT3 interactions	HSPD1 PC ATP5F1A HSP90AA1 HSP90AB1	7.25e-05	75	116	5	int:BGLT3
Interaction	GSK3A interactions	HBS1L ATG2B YWHAB PARP10 TNRC18 PTPN13 CRYBG1 AK2 CEP131 HSP90AA1 HSP90AB1	7.67e-05	464	116	11	int:GSK3A
Interaction	STK38L interactions	RC3H1 KAT6A YWHAB SPIN1 HSP90AA1	8.23e-05	77	116	5	int:STK38L
Interaction	GRK5 interactions	SPATA31A7 LARP1 YWHAB LRPPRC SPIN1 HSP90AA1 HSP90AB1	8.89e-05	182	116	7	int:GRK5
Interaction	AGR2 interactions	HSPD1 AGO2 HACD3 SYNE1 LARP1 IQCN IDH1 ECHS1 YWHAB LRPPRC GUCA1A AK2 PC ATP5F1A HSP90AA1 HSP90AB1	8.94e-05	934	116	16	int:AGR2
Interaction	EIF4E2 interactions	HBS1L AGO2 KAT6A LARP1 HTRA4 YWHAB PTPN13 C1D	8.99e-05	246	116	8	int:EIF4E2
Interaction	ATP2C2 interactions	ATP2C1 ATP2C2	9.82e-05	3	116	2	int:ATP2C2
Interaction	TSSK1B interactions	AK2 CEP131 HSP90AA1 HSP90AB1	1.18e-04	44	116	4	int:TSSK1B
Interaction	PPT1 interactions	HSPD1 AGO2 YWHAB LRPPRC DLAT ATP5F1A HSP90AA1 HSP90AB1	1.18e-04	256	116	8	int:PPT1
Interaction	AURKB interactions	HSPD1 HACD3 RBM12B LARP1 CPS1 LRPPRC AK2 CEP131 EIF3M ATP5F1A HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	1.22e-04	761	116	14	int:AURKB
Interaction	HSP90AB1 interactions	HSPD1 DDX59 AGO2 CPS1 YWHAB LRPPRC BMX TNRC18 MAPK13 PCDH7 ATP5F1A NEK11 HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	1.23e-04	960	116	16	int:HSP90AB1
Interaction	USP48 interactions	HSPD1 AGO2 LARP1 CPA3 IDH1 ECHS1 HIBADH YWHAB DLAT OGA ATP5F1A HSP90AA1 HSP90AB1	1.24e-04	668	116	13	int:USP48
Interaction	HCK interactions	MKRN3 AKAP12 LRPPRC CHD5 IL6ST HSP90AA1 HSP90AB1	1.28e-04	193	116	7	int:HCK
Interaction	EPHA6 interactions	MYO1D ECHS1 TRIP11 HSP90AB1	1.29e-04	45	116	4	int:EPHA6
Interaction	ESRRB interactions	HSPD1 HACD3 LRPPRC TAF6 MED13 ATP5F1A HSP90AA1 HSP90AB1	1.39e-04	262	116	8	int:ESRRB
Interaction	PDK2 interactions	DLAT PYCR3 HSP90AA1 HSP90AB1	1.41e-04	46	116	4	int:PDK2
Interaction	KCNA3 interactions	HSPD1 HBS1L MYO1D HACD3 ATG2B LARP1 AKAP12 LRPPRC PTPN13 TLN2 RP1 PCDH7 ATP5F1A HSP90AA1 HSP90AB1	1.43e-04	871	116	15	int:KCNA3
Interaction	ERBB2 interactions	HSPD1 ASRGL1 GMPR2 AKAP12 LRPPRC BMX CRYBG1 PC IL6ST STX6 HSP90AA1 HSP90AB1	1.50e-04	589	116	12	int:ERBB2
Interaction	CDK7 interactions	HSPD1 ECHS1 HIBADH YWHAB TAF6 PC PYCR3 ATP5F1A HSP90AA1 HSP90AA4P HSP90AB1	1.51e-04	501	116	11	int:CDK7
Interaction	NAA40 interactions	HSPD1 ATG2B LARP1 IDH1 YWHAB TRIP11 AKAP12 SCML2 PTPN13 AK2 TAF6 PC OGA ATP5F1A HSP90AA1 HSP90AB1	1.52e-04	978	116	16	int:NAA40
Interaction	OPTN interactions	HSPD1 DDX59 ATG2B LARP1 YWHAB AK2 SEMA4A COA7 EIF3M ATP5F1A	1.65e-04	422	116	10	int:OPTN
Interaction	NT5C1B interactions	HSPD1 NT5C1B	1.96e-04	4	116	2	int:NT5C1B
Interaction	EIF4G1 interactions	AGO2 RC3H1 LARP1 YWHAB LRPPRC PCDH7 EIF3M ATP5F1A HSP90AA1 HSP90AB1	2.03e-04	433	116	10	int:EIF4G1
Interaction	HSPB1 interactions	HSPD1 RC3H1 CAV2 YWHAB F13A1 GUCA1A SPIN1 TAF6 PC EIF3M ATP5F1A HSP90AA1 HSP90AB1	2.20e-04	708	116	13	int:HSPB1
Interaction	ZFP36L2 interactions	HSPD1 YWHAB LRRC9 LRPPRC ATP2C1 EIF3M HSP90AA1	2.22e-04	211	116	7	int:ZFP36L2
Interaction	YWHAQ interactions	RC3H1 HECTD4 LARP1 CPS1 ECHS1 HIBADH YWHAB TRIP11 PARD6B LRPPRC PTPN13 CEP131 PC PCDH7 ATP5F1A HSP90AA1 HSP90AB1	2.23e-04	1118	116	17	int:YWHAQ
Interaction	KCNG1 interactions	YWHAB PYCR3 HSP90AA1	2.29e-04	21	116	3	int:KCNG1
Interaction	NIPSNAP3B interactions	HSPD1 CYP24A1 CPS1	2.29e-04	21	116	3	int:NIPSNAP3B
Interaction	BTG3 interactions	SYNE1 HECTD4 TAF6 HSP90AA1 HSP90AB1	2.57e-04	98	116	5	int:BTG3
Interaction	PPP1R3D interactions	HSPD1 YWHAB LRPPRC	2.64e-04	22	116	3	int:PPP1R3D
Interaction	UNC45B interactions	HSP90AA1 HSP90AA4P HSP90AB1	2.64e-04	22	116	3	int:UNC45B
Interaction	HSPH1 interactions	RC3H1 LARP1 CAV2 CPS1 YWHAB PARD6B LRPPRC BMX HSP90AA1 HSP90AB1	2.67e-04	448	116	10	int:HSPH1
Interaction	CFD interactions	HSPD1 GPAA1 HACD3 CYP20A1 IDH1 GMPR2 ECHS1 HIBADH YWHAB TRIP11 F13A1 PARP10 LRPPRC DLAT AK2 PYCR3 ATP5F1A HSP90AA1 HSP90AB1	2.72e-04	1360	116	19	int:CFD
Interaction	AMHR2 interactions	BBS4 HSP90AA1 HSP90AA4P HSP90AB1	3.04e-04	56	116	4	int:AMHR2
Interaction	PELO interactions	HBS1L MYO1D HACD3 HTRA4 CACTIN ZKSCAN1	3.41e-04	161	116	6	int:PELO
Interaction	STYK1 interactions	MYO1D PTPN13 ARHGEF10 VPS13B HSP90AA1 HSP90AB1	3.41e-04	161	116	6	int:STYK1
Interaction	DDX46 interactions	HSPD1 AGO2 RC3H1 TAF6 PCDH7 HSP90AA1 HSP90AB1	3.46e-04	227	116	7	int:DDX46
Interaction	ANKRD55 interactions	HSPD1 YWHAB LRPPRC CFAP206 PYCR3 HSP90AA1 HSP90AB1	3.55e-04	228	116	7	int:ANKRD55
Cytoband	Ensembl 112 genes in cytogenetic band chr9q12	SPATA31A7 SPATA31A5	1.82e-04	8	118	2	chr9q12
GeneFamily	Heat shock 90kDa proteins	HSP90AA1 HSP90AB1	1.51e-04	5	71	2	586
GeneFamily	ATPases Ca2+ transporting	ATP2C1 ATP2C2	5.38e-04	9	71	2	1209
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	PTPN13 TLN2 FRMPD3	9.96e-04	50	71	3	1293
GeneFamily	Zinc fingers ZZ-type\|Lysine acetyltransferases	KAT6A ELP3	1.99e-03	17	71	2	486
GeneFamily	PDZ domain containing	HTRA4 PARD6B PTPN13 FRMPD3	3.01e-03	152	71	4	1220
Coexpression	WALLACE_PROSTATE_CANCER_DN	LAMA4 CAV2 AKAP12	1.67e-06	6	116	3	M12533
Coexpression	DODD_NASOPHARYNGEAL_CARCINOMA_UP	HSPD1 AGO2 ZNF473 HACD3 LAMA4 IDH1 ELP3 ARMC1 LRPPRC SLC25A36 SCML2 ATP2C1 ARHGEF10 SPIN1 AK2 CAMTA1 COA7 EIF3M STX6	1.30e-05	1407	116	19	M14427
Coexpression	ONKEN_UVEAL_MELANOMA_DN	HSPD1 HACD3 LAMA4 CAV2 GMPR2 CPS1 CREG1 SLC25A36 SPIN1 OGA HSP90AB1	2.55e-05	533	116	11	M2605
Coexpression	GSE17721_CTRL_VS_LPS_12H_BMDC_UP	ATG2B ELP3 TRIP11 GUCA1A TMEM131L ATP5F1A IL6ST	3.03e-05	199	116	7	M3701
Coexpression	GSE3982_MAST_CELL_VS_NKCELL_UP	MYO1D LARP1 IDH1 AKAP12 CAMTA1 COA7 ATP5F1A	3.03e-05	199	116	7	M5450
Coexpression	GSE16385_ROSIGLITAZONE_IL4_VS_ROSIGLITAZONE_ALONE_STIM_MACROPHAGE_DN	HSPD1 HACD3 CYP11A1 GRHL2 F13A1 SEPSECS HSP90AA1	3.13e-05	200	116	7	M7989
Coexpression	PATIL_LIVER_CANCER	AGO2 GPAA1 HACD3 RBM12B LAMA4 LARP1 F13A1 ARMC1 COLEC12 ZKSCAN1 TAF6 NOTCH3	3.72e-05	660	116	12	M1195
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_XPCS_DN	AGO2 ATP2C1 ARHGEF10 TMEM131L VPS13B	3.85e-05	85	116	5	M10575
Coexpression	BERENJENO_TRANSFORMED_BY_RHOA_DN	MYO1D LAMA4 IDH1 AKAP12 PTPN13 NACC2 CRYBG1 OGA IL6ST	7.15e-05	398	116	9	M7514
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LAMA4 AKAP12 COLEC12 PCDH7 IL6ST HSP90AA1 HSP90AB1	7.98e-07	193	117	7	cf3cbf79ccd34ddcf06ec6194a18a7afd7f91f39
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-Stress_sig-F_2\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPD1 SYNE1 PTPN13 ERAP2 FRMPD3 HSP90AA1 HSP90AB1	8.85e-07	196	117	7	ea8eceacc5d5e1a22b77c31e7c45985dc7bb15de
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SYNE1 LAMA4 CALML6 AKAP12 COLEC12 TAGLN IL6ST	9.16e-07	197	117	7	fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCell	Megakaryocytic-erythropoietic-Erythro-cells-Basophilic_Erythroblast\|Megakaryocytic-erythropoietic / Lineage, cell class and subclass	HSPD1 CPA3 ECHS1 LRPPRC AK2 EIF3M ATP5F1A	9.80e-07	199	117	7	6f159c1215439ec22374903124085746fa8da333
ToppCell	10x5'-bone_marrow-Mast-Mast_cells\|bone_marrow / Manually curated celltypes from each tissue	CYP11A1 CPA3 CAV2 AKAP12 ATP2C1 CFAP206	4.31e-06	161	117	6	15ba7e69699558353cfeecdcf1dbc2e147379ed6
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	KAT6A DGKA NT5C1B TMEM131L CRYBG1 IL6ST	4.47e-06	162	117	6	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5\|TCGA-Ovary / Sample_Type by Project: Shred V9	RBM12B RC3H1 HECTD4 ZKSCAN1 OGA NEK11	5.14e-06	166	117	6	32d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SYNE1 HECTD4 CAV2 GRHL2 PTPN13 SPIN1	5.14e-06	166	117	6	89e2b8453180983533faccb4275867861876d7ee
ToppCell	severe-Myeloid-Eosinophils\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ASRGL1 CYP11A1 SYNE1 CPA3 CAV2 AKAP12	5.89e-06	170	117	6	863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAV2 MYRFL COLEC12 BMX KCNT2 IL6ST	6.30e-06	172	117	6	fc092a0631555d79e00ef9890cbd806e15bca2d4
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAV2 MYRFL COLEC12 BMX KCNT2 IL6ST	6.30e-06	172	117	6	745725bd10c82017d678463b8fef0d2dcf09a8fd
ToppCell	RV-11._Adipocyte\|World / Chamber and Cluster_Paper	LAMA4 IDH1 AKAP12 TLN2 PC OGA	7.42e-06	177	117	6	f0edf04930692418953e4f00a917257804ec0ffd
ToppCell	metastatic_Brain-T/NK_cells-Exhausted_Tfh\|T/NK_cells / Location, Cell class and cell subclass	AGO2 IQCN CAV2 TNRC18 COA7 NOTCH3	7.66e-06	178	117	6	9a3581a0158dfa5a1cc942f8c532afb5e38b272a
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	LAMA4 AKAP12 TLN2 TAGLN PCDH7 NOTCH3	8.17e-06	180	117	6	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	COVID-19_Mild-CD4+_T_activated\|COVID-19_Mild / Disease condition and Cell class	AGO2 DGKA TMEM131L OGA ATP5F1A IL6ST	8.70e-06	182	117	6	877b6e611626628e709568747512f2827ebb2795
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA4 CAV2 KCNT2 TMEM131L TAGLN NOTCH3	1.11e-05	190	117	6	5681c211baeed4af82a2bbc13420f6a7b487581c
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO1D IDH1 CPS1 ATP2C2 CRYBG1 URAD	1.14e-05	191	117	6	a8d77095ba20b47fc70ba04f80759fbce873253d
ToppCell	Children_(3_yrs)-Epithelial\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CCDC141 GRHL2 PARD6B PTPN13 ATP2C2 RP1	1.14e-05	191	117	6	e432c6e1ae82dddf84314ce73d2b7a991630d905
ToppCell	IPF-Epithelial-Ciliated\|Epithelial / Disease state, Lineage and Cell class	SYNE1 LRGUK CFAP54 CFAP206 RP1 NEK11	1.21e-05	193	117	6	ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D KCNT2 TMEM131L TAGLN PCDH7 NOTCH3	1.25e-05	194	117	6	5c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D KCNT2 TMEM131L TAGLN PCDH7 NOTCH3	1.25e-05	194	117	6	ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D KCNT2 TMEM131L TAGLN PCDH7 NOTCH3	1.25e-05	194	117	6	ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	MYO1D SYNE1 GRHL2 LRGUK CFAP54 RP1	1.29e-05	195	117	6	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D LAMA4 KCNT2 TMEM131L TAGLN NOTCH3	1.29e-05	195	117	6	edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCell	IPF-Multiplet\|IPF / Disease state, Lineage and Cell class	MYO1D SYNE1 GRHL2 LRGUK CFAP54 RP1	1.29e-05	195	117	6	eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MYO1D SYNE1 GRHL2 PARD6B PTPN13 ATP2C2	1.29e-05	195	117	6	9406866f99555198a9be311fbd65751b70f35446
ToppCell	control-Others-CD34+_GATA2+_cells\|Others / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	HSPD1 CPA3 AK2 EIF3M ATP5F1A HSP90AB1	1.33e-05	196	117	6	25994ca143701c72d2f84a3b6d348fcfa1d26a54
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D LAMA4 KCNT2 TAGLN PCDH7 NOTCH3	1.33e-05	196	117	6	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D LAMA4 KCNT2 TAGLN PCDH7 NOTCH3	1.33e-05	196	117	6	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 LRRC9 LRGUK CFAP54 RP1 NEK11	1.36e-05	197	117	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	Epithelial_cells-AT2_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	ASRGL1 CREG1 CCDC141 COLEC12 FGGY FAM177A1	1.36e-05	197	117	6	59aa28a377315dfcda4d9b6ecd3419157654f24e
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SYNE1 LAMA4 CAV2 AKAP12 TAGLN PCDH7	1.36e-05	197	117	6	ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCell	AT2_cells\|World / lung cells shred on cell class, cell subclass, sample id	SYNE1 CCDC141 PARD6B PTPN13 FGGY FAM177A1	1.40e-05	198	117	6	92c569c3b8a9fca2d4682cbf77ee8149bcc0a80a
ToppCell	368C-Endothelial_cells-Endothelial-A_(Artery)\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HSPD1 ASRGL1 YWHAB EIF3M ATP5F1A IL6ST	1.40e-05	198	117	6	6b8baa0b76242736f6dba482cdaad019256877ea
ToppCell	368C-Endothelial_cells-Endothelial-A_(Artery)-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HSPD1 ASRGL1 YWHAB EIF3M ATP5F1A IL6ST	1.40e-05	198	117	6	8519c7bd5f6c5a97f5e43f4729b1411d3b07e4c8
ToppCell	Biopsy_Other_PF-Epithelial-AT2\|Biopsy_Other_PF / Sample group, Lineage and Cell type	SYNE1 CCDC141 PARD6B PTPN13 ATP2C2 FGGY	1.44e-05	199	117	6	9a65acfe9bf500db72142469cf17bf0973540001
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SYNE1 LAMA4 AKAP12 COLEC12 TAGLN IL6ST	1.44e-05	199	117	6	e1849505b92820a219c5a2c35492bdd55579fb48
ToppCell	(01)_IL1RL1+-(2)_GFP_FOXI1\|(01)_IL1RL1+ / shred by cell type by condition	TRIP11 AKAP12 TAGLN PCDH7 EIF3M HSP90AA1	1.44e-05	199	117	6	a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SYNE1 LAMA4 AKAP12 COLEC12 TAGLN IL6ST	1.49e-05	200	117	6	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	343B-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CAV2 MYRFL TAGLN CAMTA1 PCDH7 NOTCH3	1.49e-05	200	117	6	4fb6fd703aca9a992924245105ad99163146a415
ToppCell	Lung_Parenchyma-Control-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 CCDC141 PARD6B PTPN13 ATP2C2 FGGY	1.49e-05	200	117	6	c2bde99b3bc7a8740441c1a0c1394892b940b857
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SYNE1 LAMA4 AKAP12 COLEC12 TAGLN IL6ST	1.49e-05	200	117	6	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	Lung_Parenchyma-Control-Epithelial-Epithelial\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	SYNE1 CCDC141 PARD6B PTPN13 ATP2C2 FGGY	1.49e-05	200	117	6	3ff9abd5e07780a59d5571da906fa15f00a1d5c2
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SYNE1 LAMA4 AKAP12 COLEC12 TAGLN IL6ST	1.49e-05	200	117	6	3bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SYNE1 LAMA4 AKAP12 COLEC12 TAGLN IL6ST	1.49e-05	200	117	6	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SYNE1 LAMA4 AKAP12 COLEC12 TAGLN IL6ST	1.49e-05	200	117	6	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	Parenchyma_Control_(B.)-Epithelial-TX\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	SYNE1 CCDC141 PARD6B PTPN13 ATP2C2 FGGY	1.49e-05	200	117	6	9970e9bde6aa2ff3aef60dcb065ff15b7463e147
ToppCell	343B-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	CAV2 MYRFL TAGLN CAMTA1 PCDH7 NOTCH3	1.49e-05	200	117	6	b50de1f8c8f598e281951e4587f2d96c11aac836
ToppCell	PND01-Immune-Immune_Myeloid-Granulocytic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYP11A1 SYNE1 CPA3 BMX SEMA4A	4.48e-05	148	117	5	74f1f9d1a53dc1a09cb6a504cbbdc7496c5b6879
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRC9 LRGUK CFAP54 ATP2C2 RP1	4.93e-05	151	117	5	81cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRC9 LRGUK CFAP54 ATP2C2 RP1	4.93e-05	151	117	5	9cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRC9 LRGUK CFAP54 ATP2C2 RP1	5.59e-05	155	117	5	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRC9 LRGUK CFAP54 ATP2C2 RP1	5.59e-05	155	117	5	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 AKAP12 CCDC194 KCNT2 EPHX4	5.76e-05	156	117	5	dd41ed918b07fa248da458a629b3c53cb7ea8764
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 AKAP12 CCDC194 KCNT2 EPHX4	5.76e-05	156	117	5	abf9dd075b1ca8f613c660cc82f8a5af071fb6ab
ToppCell	343B-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HSPD1 IQCN SEMA4A HSP90AA1 HSP90AB1	6.49e-05	160	117	5	21f7c0337fbd99e4a20650920d8302d7318bd25e
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	SYNE1 HECTD4 CAV2 GRHL2 PTPN13	6.89e-05	162	117	5	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	lung-Ciliated_Epithelia\|lung / shred on tissue and cell subclass	HBS1L CFAP54 CFAP206 RP1 NEK11	7.95e-05	167	117	5	26cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCell	Club_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	GLB1L3 CYP24A1 FCGBP PCDH7 NOTCH3	7.95e-05	167	117	5	dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCell	-Hematopoietic_Mast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HBS1L CPA3 ATP5F1A	8.05e-05	32	117	3	ca3d87cac849c1b713acd984626f214f5c8e1433
ToppCell	-Hematopoietic_Mast-Mast_cells-Mast-cells\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HBS1L CPA3 ATP5F1A	8.05e-05	32	117	3	c6b707107c661f81e5afa945dd62b37a73bfadf9
ToppCell	-Hematopoietic_Mast-Mast_cells\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HBS1L CPA3 ATP5F1A	8.05e-05	32	117	3	de636b6fbdc9368ef6ce7157acbf84e28330cd94
ToppCell	3'-Adult-LargeIntestine-Epithelial-epithelial_progenitor_cell-Stem_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HACD3 IDH1 CRYBG1 CAMTA1 HSP90AA1	8.18e-05	168	117	5	b08458164d270d625b8ee390122d1c2ce8c653db
ToppCell	droplet-Spleen-nan-21m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA3 IDH1 GRHL2 F13A1 FCGBP	8.65e-05	170	117	5	03cb4e508356f85372a588c8d1c6babf2a012683
ToppCell	COVID-19-Heart-CM_+_Macrophage\|Heart / Disease (COVID-19 only), tissue and cell type	IDH1 CCDC141 F13A1 COLEC12 FCGBP	8.65e-05	170	117	5	4232fe937909f93d3736988c707b8f95ce993398
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	GLB1L3 RANBP6 PTPN13 ZKSCAN1 IL6ST	8.65e-05	170	117	5	adb625124832b0786a590e8f75b61e7263a1e0d4
ToppCell	3'_v3-bone_marrow-Mast-Mast_cell_lympho\|bone_marrow / Manually curated celltypes from each tissue	ATG2B CPA3 IQCN CAV2 AKAP12	8.65e-05	170	117	5	4dedf482cd4521b3f87d2b5ae80f7a3ea8686a15
ToppCell	droplet-Spleen-nan-21m-Hematologic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA3 IDH1 CREG1 F13A1 FCGBP	8.89e-05	171	117	5	9498c35b2a2c3a339dc8c5d49c8ec20d8ad52753
ToppCell	control-Myeloid-Eosinophils\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	ASRGL1 CYP11A1 CPA3 CAV2 AKAP12	8.89e-05	171	117	5	82f736c33ed96c0865618e8f8eb82a5487126bdc
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10\|TCGA-Brain / Sample_Type by Project: Shred V9	CYP11A1 LRRC9 COLEC12 CFAP54 NEK11	8.89e-05	171	117	5	74be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCell	droplet-Spleen-nan-21m-Hematologic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CPA3 IDH1 CREG1 F13A1 FCGBP	8.89e-05	171	117	5	db544252f98e073e5bb4bec4a110cd58e6434435
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPD1 IDH1 HIBADH ATP2C2 PC	9.13e-05	172	117	5	feaaf8ca7983d04a59ed0a7b3fb0e6d4b3a055f2
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPD1 IDH1 HIBADH ATP2C2 PC	9.13e-05	172	117	5	9adfb4a65669cc536343616637058d0a4728013f
ToppCell	facs-Liver-Non-hepatocytes-3m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPD1 IDH1 HIBADH ATP2C2 PC	9.13e-05	172	117	5	8aed9c113f27d00401c272a3684495a4bc75bd0f
ToppCell	COVID-19-kidney-PEC\|kidney / Disease (COVID-19 only), tissue and cell type	SYNE1 LAMA4 AKAP12 CFAP54 KCNT2	9.13e-05	172	117	5	36a96714a0eb6ac438648135336c9791881ddadb
ToppCell	Frontal_cortex-Macroglia\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MKRN3 ASRGL1 CYP20A1 FABP7 ARHGEF10	9.39e-05	173	117	5	ac70145e093ef0df43811e7c67a865ccdd45a5e3
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-skeletal_muscle_satellite_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GLB1L3 FABP7 TLN2 NOTCH3 HSP90AA1	9.64e-05	174	117	5	f230d23618a6487f2664efb2c677e0a4559e2bf4
ToppCell	15-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	LAMA4 HTRA4 SERPINA11 COLEC12 SEMA4A	9.64e-05	174	117	5	fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCell	10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages\|bone_marrow / Manually curated celltypes from each tissue	CREG1 F13A1 COLEC12 FCGBP SEMA4A	9.64e-05	174	117	5	0746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP11A1 CPA3 PARD6B KCNJ2 PC	9.91e-05	175	117	5	1b35acece23712ab7e3f92d9d68266efd38b3ef5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 AKAP12 KCNJ2 TAGLN NOTCH3	9.91e-05	175	117	5	1b4cefae400bf756d09ece32d3f5c0bd4c6ad73f
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP11A1 CPA3 PARD6B KCNJ2 PC	9.91e-05	175	117	5	a9f88054e2c28d604c65ed785f63021aadb7f4c8
ToppCell	3'_v3-blood-Mast-Mast_cells\|blood / Manually curated celltypes from each tissue	CPA3 CAV2 AKAP12 CFAP54 MED13	1.02e-04	176	117	5	b9da3deaf62622d47eb30b6be7548253eee95597
ToppCell	LPS-IL1RA+antiTNF\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYO1D IDH1 PTPN13 TMEM131L PCDH7	1.05e-04	177	117	5	b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DDX59 HTRA4 CCDC141 AKAP12 COLEC12	1.05e-04	177	117	5	3a85aa2bf3f2fdbea57d22d68e022cb3f6c2eb65
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPAA1 RBM12B KCNT2 FGGY NOTCH3	1.10e-04	179	117	5	e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell	3'_v3-bone_marrow-Mast\|bone_marrow / Manually curated celltypes from each tissue	ASRGL1 CYP11A1 CPA3 CAV2 AKAP12	1.13e-04	180	117	5	b37ee81b792213d6595b4ec65d04bc35d83321c7
ToppCell	severe-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	CYP11A1 SYNE1 CPA3 CAV2 AKAP12	1.13e-04	180	117	5	ac03812b1409435c55d323a7516deeac82bd3509
ToppCell	3'_v3-bone_marrow-Mast-Mast_cells\|bone_marrow / Manually curated celltypes from each tissue	ASRGL1 CYP11A1 CPA3 CAV2 AKAP12	1.16e-04	181	117	5	30ec4635474ee0f0ea1415ec0ba7f008d97e8c1a
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	DGKA TMEM131L CRYBG1 OGA IL6ST	1.16e-04	181	117	5	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	BAL-Control-cDC_8\|Control / Compartment, Disease Groups and Clusters	BBS4 AKAP12 PARP10 TAF6 MAPK13	1.16e-04	181	117	5	f370161afef2ec827a7b194c06abb9ac1a507cbb
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	AGO2 DGKA TMEM131L OGA IL6ST	1.19e-04	182	117	5	1aea96ee211f7b9caef7fd385233f51be6021a73
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	AGO2 DGKA TMEM131L OGA IL6ST	1.19e-04	182	117	5	b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AGO2 DGKA TMEM131L OGA IL6ST	1.19e-04	182	117	5	c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	AGO2 DGKA TMEM131L OGA IL6ST	1.19e-04	182	117	5	4cb182ef39be2044a6ad7266f332d4177591e550
ToppCell	COVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated\|COVID-19_Mild / Disease group, lineage and cell class	AGO2 DGKA TMEM131L OGA IL6ST	1.22e-04	183	117	5	7717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRHL2 FCGBP CHD5 ATP2C2 MAPK13	1.22e-04	183	117	5	4de2082dca2569d3aac3c9b466f27971c82d302b
ToppCell	droplet-Heart-4Chambers-21m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GRHL2 FCGBP CHD5 ATP2C2 MAPK13	1.22e-04	183	117	5	a046b569bc10083d471b420eb2c6fee93437602d
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CAV2 HTRA4 AKAP12 BMX TAGLN	1.25e-04	184	117	5	087666ba949b129c53d7ace40f9e543e3875a7de
ToppCell	Pericytes-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	LAMA4 CPS1 AKAP12 TAGLN NOTCH3	1.25e-04	184	117	5	3d2d55d0f22874be21665ab37da710482f77fc36
Drug	Xanthine	HSPD1 ECHS1 DLAT AK2 ATP5F1A HSP90AB1	4.28e-07	57	115	6	ctd:D019820
Drug	Cinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	BBS4 TRIP11 SNX19 ZKSCAN1 ATP2C2 TMEM131L FGGY PYCR3 IL6ST	7.53e-07	198	115	9	7174_DN
Drug	N-nitrosomorpholine	HSPD1 MYO1D IDH1 CPS1 ECHS1 FABP7 ATP2C1 AK2 PC ATP5F1A HSP90AB1	1.18e-06	338	115	11	ctd:C002741
Drug	magnesium	HSPD1 MYO1D LAMA4 DGKA IDH1 CPS1 NT5C1B ATP2C1 KCNJ2 ATP2C2 DLAT AK2 MAPK13 PC ATP5F1A NEK11 NOTCH3 SMC1B HSP90AA1 HSP90AA2P HSP90AB1	2.71e-06	1325	115	21	CID000000888
Drug	compound 9b	SYNE1 MAPK13 HSP90AA1 HSP90AA2P	2.81e-06	20	115	4	CID000207510
Drug	AC1L1IZ2	HSPD1 MYO1D CPS1 GUCA1A KCNJ2 DLAT AK2 ATP5F1A HSP90AA1 HSP90AA2P	3.36e-06	304	115	10	CID000004795
Drug	NSC330499	HSP90AA1 HSP90AA2P HSP90AB1	4.33e-06	7	115	3	CID000433447
Drug	phenyldichloroarsine	HSP90AA1 HSP90AA2P HSP90AB1	6.90e-06	8	115	3	CID000012762
Drug	estradiol, USP; Down 200; 0.1uM; MCF7; HG-U133A	ZNF473 LAMA4 CPS1 FABP7 ARHGEF10 DLAT OGA FGGY	7.87e-06	199	115	8	365_DN
Drug	5,8-quinolinedione	HSP90AA1 HSP90AA2P HSP90AB1	1.03e-05	9	115	3	CID000388306
Drug	Pu-3	HSP90AA1 HSP90AA2P HSP90AB1	2.01e-05	11	115	3	CID000448965
Drug	3-amino-5-chlorobenzoic acid	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID010986726
Drug	monocillin III	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID006478910
Drug	pochonin A	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID006478909
Drug	PU-H71	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID009549213
Drug	9-Butyl-8-(3,4,5-Trimethoxybenzyl)-9h-Purin-6-Amine	HSP90AA1 HSP90AB1	2.53e-05	2	115	2	DB02754
Drug	1uyc	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID000448969
Drug	PU-9	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID000448971
Drug	P u 0	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID000448974
Drug	2qf6	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID013373715
Drug	Geldanamycin	HSP90AA1 HSP90AB1	2.53e-05	2	115	2	DB02424
Drug	CHEBI:42139	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID011562562
Drug	2qfo	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID000600769
Drug	3eko	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID011160307
Drug	8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE	HSP90AA1 HSP90AB1	2.53e-05	2	115	2	DB07877
Drug	1uyi	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID005289232
Drug	4-[4-(2,3-DIHYDRO-1,4-BENZODIOXIN-6-YL)-3-METHYL-1H-PYRAZOL-5-YL]-6-ETHYLBENZENE-1,3-DIOL	HSP90AA1 HSP90AB1	2.53e-05	2	115	2	DB07594
Drug	NSC683666	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID005469153
Drug	H 64	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID006914564
Drug	SureCN4151355	HSP90AA1 HSP90AA2P	2.53e-05	2	115	2	CID015942101
Drug	1alpha,20-dihydroxyvitamin D3	CYP11A1 CYP24A1	2.53e-05	2	115	2	ctd:C539020
Drug	Phlorhizin	HSPD1 HACD3 ECHS1 HIBADH PC ATP5F1A HSP90AA1 HSP90AB1	2.62e-05	235	115	8	ctd:D010695
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	ELP3 PARD6B CACTIN ARHGEF10 COA7 PYCR3 NOTCH3	5.00e-05	189	115	7	5203_DN
Drug	Phenformin hydrochloride [834-28-6]; Down 200; 16.6uM; PC3; HT_HG-U133A	RBM12B KAT6A SLC25A36 ATP2C2 AK2 OGA IL6ST	5.35e-05	191	115	7	4283_DN
Drug	AC1L9PMA	HSP90AA1 HSP90AA2P HSP90AB1	5.46e-05	15	115	3	CID000451405
Drug	Heliotrine [303-33-3]; Down 200; 12.8uM; PC3; HT_HG-U133A	MYO1D ZKSCAN1 AK2 PC IL6ST STX6 NOTCH3	5.90e-05	194	115	7	3717_DN
Drug	Equilin [474-86-2]; Down 200; 15uM; MCF7; HT_HG-U133A	PARD6B CACTIN SCML2 AK2 SEMA4A MAPK13 NOTCH3	5.90e-05	194	115	7	5255_DN
Drug	Ioxaglic acid [59017-64-0]; Down 200; 3.2uM; MCF7; HT_HG-U133A	HBS1L KAT6A SNX19 PARD6B CEP131 OGA PYCR3	6.50e-05	197	115	7	3528_DN
Drug	diethylene glycol	HSPD1 IDH1 HTRA4 HIBADH SCML2	6.77e-05	84	115	5	CID000008117
Drug	Xylometazoline hydrochloride [1218-35-5]; Down 200; 14.2uM; MCF7; HT_HG-U133A	ATG2B BBS4 ELP3 CACTIN ATP2C1 TLN2 EIF3M	6.93e-05	199	115	7	7020_DN
Drug	NADP(H	CYP11A1 CYP24A1 IDH1 GMPR2 ECHS1 HIBADH DLAT PC PYCR3 HSP90AA1 HSP90AA2P	7.49e-05	527	115	11	CID000000930
Drug	pochonin D	HSP90AA1 HSP90AA2P	7.56e-05	3	115	2	CID006478913
Drug	azaquinone	HSP90AA1 HSP90AA2P	7.56e-05	3	115	2	CID000099132
Drug	Radicicol	DLAT HSP90AB1	7.56e-05	3	115	2	DB03758
Drug	d 1 v	HSP90AA1 HSP90AA2P	7.56e-05	3	115	2	CID000683940
Drug	AC1MD0RC	HSP90AA1 HSP90AA2P	7.56e-05	3	115	2	CID002829073
Drug	HM-9	HSP90AA1 HSP90AA2P	7.56e-05	3	115	2	CID000433437
Drug	Glyoxylspermidine	HSP90AA1 HSP90AA2P	7.56e-05	3	115	2	CID000133564
Drug	tienilic acid	CYP11A1 CYP24A1 CYP20A1 SEPSECS CEP131	1.10e-04	93	115	5	CID000038409
Drug	NCI60_002052	IL6ST HSP90AA1 HSP90AA2P	1.34e-04	20	115	3	CID006801032
Drug	dimethyl pimelimidate	HSP90AA1 HSP90AA2P HSP90AB1	1.34e-04	20	115	3	CID000065403
Drug	N-(5-methylisoxazol-3-yl)-2-(4-(thiophen-2-yl)-6-(trifluoromethyl)pyrimidin-2-ylthio)acetamide	HSP90AA1 HSP90AB1	1.51e-04	4	115	2	ctd:C576667
Drug	uranyl chloride	HSP90AA1 HSP90AA2P	1.51e-04	4	115	2	CID000082259
Drug	methoxyhydroquinone	HSP90AA1 HSP90AA2P	1.51e-04	4	115	2	CID000069988
Drug	11p110	HSP90AA1 HSP90AA2P	1.51e-04	4	115	2	CID002382787
Drug	Ab-9	HSPD1 HSP90AA1 HSP90AA2P	1.56e-04	21	115	3	CID006540280
Drug	beryllium fluoride	HSPD1 ATP5F1A HSP90AA1 HSP90AA2P HSP90AB1	1.78e-04	103	115	5	CID000024589
Drug	tamoxifen aziridine	HSP90AA1 HSP90AA2P HSP90AB1	1.80e-04	22	115	3	CID003033894
Drug	CCT018159	HSP90AA1 HSP90AA2P HSP90AB1	1.80e-04	22	115	3	CID005327091
Drug	2-butenedioate	HSPD1 ASRGL1 IDH1 F13A1 ATP2C1 ATP2C2 PC	1.89e-04	234	115	7	CID000000723
Drug	beta-NADP	CYP11A1 CYP24A1 IDH1 GMPR2 HIBADH DLAT PC PYCR3 HSP90AA1 HSP90AA2P	1.93e-04	490	115	10	CID000000929
Drug	S2A	HSP90AA1 HSP90AA2P HSP90AB1	2.07e-04	23	115	3	CID016058643
Disease	Leigh syndrome	LRPPRC DLAT PC	3.27e-06	8	116	3	cv:C0023264
Disease	Endotoxemia	HSPD1 CPS1 ATP5F1A	3.27e-06	8	116	3	C0376618
Disease	isobutyrylglycine measurement	GLB1L3 CPS1	9.15e-05	4	116	2	EFO_0800029
Disease	cancer (implicated_via_orthology)	RANBP6 IDH1 NOTCH3 HSP90AA1 HSP90AA4P HSP90AA2P HSP90AB1	9.47e-05	268	116	7	DOID:162 (implicated_via_orthology)
Disease	urolithiasis	CYP24A1 CPS1 HIBADH VPS13B	1.13e-04	63	116	4	MONDO_0024647
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2C1 ATP2C2	2.27e-04	6	116	2	DOID:0050429 (implicated_via_orthology)
Disease	arteriosclerosis (is_implicated_in)	HSPD1 F13A1 IL6ST	2.46e-04	31	116	3	DOID:2349 (is_implicated_in)
Disease	serum metabolite measurement	ASRGL1 GPAA1 CYP24A1 CPS1 ECHS1 GRHL2 F13A1 LRPPRC KCNT2 ERAP2 TLN2 PYCR3	3.53e-04	945	116	12	EFO_0005653
Disease	mean corpuscular hemoglobin concentration	HBS1L AGO2 GPAA1 HACD3 HECTD4 LARP1 GMPR2 CPS1 COLEC12 PYCR3 MED13 VPS13B HSP90AB1	4.12e-04	1105	116	13	EFO_0004528
Disease	Bardet-Biedl syndrome (implicated_via_orthology)	BBS4 CEP131	8.23e-04	11	116	2	DOID:1935 (implicated_via_orthology)
Disease	obsolete_red blood cell distribution width	HBS1L AGO2 MYO1D RC3H1 HECTD4 LARP1 CPS1 PARP10 COLEC12 ZKSCAN1 CRYBG1 RP1 PYCR3 HSP90AB1	8.36e-04	1347	116	14	EFO_0005192
Disease	Mitochondrial disease	LRPPRC DLAT PC	9.56e-04	49	116	3	cv:C0751651
Disease	Malignant neoplasm of breast	DDX59 SYNE1 CYP24A1 ELP3 AKAP12 FABP7 KCNT2 CHD5 EIF3M VPS13B NOTCH3 HSP90AA1	1.08e-03	1074	116	12	C0006142
Disease	Myeloid Leukemia	AGO2 ATG2B	2.25e-03	18	116	2	C0023470
Disease	Leukemia, Monocytic, Chronic	AGO2 ATG2B	2.25e-03	18	116	2	C0023466
Disease	venous thromboembolism, fibrinogen measurement	HECTD4 CPS1 PARP10	2.36e-03	67	116	3	EFO_0004286, EFO_0004623
Disease	Cannabis use, age at onset	LARP1 ATP2C2	2.51e-03	19	116	2	EFO_0004847, EFO_0007585
Disease	intrahepatic cholangiocarcinoma (is_marker_for)	HSP90AA1 HSP90AB1	2.51e-03	19	116	2	DOID:4928 (is_marker_for)
Disease	Hereditary hearing loss and deafness	GRHL2 LRPPRC DLAT PC	2.68e-03	146	116	4	cv:C0236038
Disease	hyperglycemia (biomarker_via_orthology)	HSPD1 CYP11A1	3.06e-03	21	116	2	DOID:4195 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
MDIEKVNSMDLGEFV	URAD	1	A6NGE7
EGIASATMFDGAKDM	NT5C1B	441	Q96P26
YDDMAAAMKAVTEQG	YWHAB	21	P31946
LEFDSEMVEMAQKLG	BBS4	411	Q96RK4
EMIGDVFVASFSKSM	ARHGEF10	496	O15013
FKAAVMEIGRSAEMQ	CFAP54	1396	Q96N23
FQAMTAEGEVTMETS	CAMTA1	681	Q9Y6Y1
GTEELFKDDVEGMMS	CHD5	1196	Q8TDI0
AETLAGVKSQEMVME	AKAP12	1141	Q02952
TNGEVEMDASIMDGK	ASRGL1	71	Q7L266
MIKEGSMSEDEFFQE	BMX	446	P51813
MKAQQVVKSESGEEM	ARMC1	206	Q9NVT9
MAGDFVNMVEKGIID	HSPD1	506	P10809
EEFVAMMTGESFKLI	CALML6	166	Q8TD86
GENSEFGEVFKMMQA	ATP2C1	236	P98194
ESSQFGEVFKMMQAE	ATP2C2	266	O75185
AMEEIDMQQGTSSVK	ATG2B	1416	Q96BY7
QAEEMVEFSSGLKGM	ATP5F1A	91	P25705
EFGIMVKDEMTDVTG	AGO2	396	Q9UKV8
SDIITGAQEVEMMTK	CFAP206	281	Q8IYR0
QEFGVNFSVMSSEKM	RBM12B	481	Q8IXT5
DVVAAGSVEMMNVES	RC3H1	831	Q5TC82
TDMAFKTSVAVEMAG	IQCN	616	Q9H0B3
ERGVTMDVGMTKFET	HBS1L	321	Q9Y450
IEVSGKSLDQVTDMM	PARD6B	221	Q9BYG5
EDGMKLATMAVANGF	KCNJ2	16	P63252
MVGQEGSDTSKLEMF	LRRC9	26	Q6ZRR7
AEAQVVMMGLDSAGK	ARL11	11	Q969Q4
EEMEQMDGRKNTFTA	LARP1	611	Q6PKG0
KAFMEALQAGADISM	HSP90AB1	111	P08238
NFEMEGDSEVIMESK	FAM177A1	191	Q8N128
SENAMGSTMVEEQFA	GPAA1	51	O43292
IFGTMEEMQNKAVVF	HACD3	231	Q9P035
NDAFMEVEMAEVTKI	EPHX4	306	Q8IUS5
NEVILFEKMMSGSDI	GLB1L3	631	Q8NCI6
ATMDAGKLVSDEMVV	AK2	66	P54819
TFMGMAVENKEISFD	EIF3M	281	Q7L2H7
VVDEADTMLKMGFQQ	DDX59	351	Q5T1V6
FENSIGAVDEMLKTM	C1D	21	Q13901
EMDEAKAQGTQMGAE	CCDC194	121	A0A1B0GVG4
VVAMAKESVNAAFEM	ECHS1	236	P30084
DNEKGFDVASMMSVT	DLAT	601	P10515
VTVMDADKGRNAEMS	PCDH7	661	O60245
VVEKMDNVTGGMETS	COLEC12	61	Q5KU26
NMAKGESLMGEVATD	NOTCH3	1706	Q9UM47
QEMMKEIDYDGSGSV	DGKA	161	P23743
MVDKDQIFMENVGAV	MYRFL	531	Q96LU7
MRESAMQKLGTEVFE	NEK11	571	Q8NG66
QTDLQKIMGMEFSEE	MAPK13	111	O15264
GVMKSRSNVDMDFEV	F13A1	511	P00488
KAMDFVSQEQGEMVM	LRPPRC	876	P42704
IAANMDTVGTFEMAK	GMPR2	51	Q9P2T1
ISQDVFDEMVNMGKF	LRGUK	466	Q96M69
ANMVVVDKESTMSAE	KCNT2	796	Q6UVM3
MKEVSFDGNDLENMV	HECTD4	1006	Q9Y4D8
FGSQEIMTEKDMELF	KAT6A	471	Q92794
GSAMNVVFSEDEMKK	CPS1	1136	P31327
GMKDSDMDYVQIDAT	HTRA4	306	P83105
IDDMVAQAMKSEGGF	IDH1	251	O75874
GSGQMKMFQEVSAAD	IL6ST	861	P40189
TFILNMESMVEGFKV	GRHL2	606	Q6ISB3
AANMMVDFRVSEKES	CPA3	61	P15088
EAAAKTMMEKNEFVS	CCDC141	516	Q6ZP82
AGDEAVNFIMAIKTM	CYP24A1	231	Q07973
ESVMVNISAKAEMIG	FCGBP	86	Q9Y6R7
ASGDFASVQEAMAKM	FGGY	496	Q96C11
FSEQVAVGETDAKMM	FRMPD3	156	Q5JV73
MSFEDIKANVTEMLA	CYP11A1	311	P05108
SVDKVEFIVMGGTFM	ELP3	161	Q9H9T3
MGNVMEGKSVEELSS	GUCA1A	1	P43080
AFLGENAEVKEMMTT	ERAP2	526	Q6P179
KEGMGQDEAQFSVEM	CACTIN	611	Q8WUQ7
KAFMEALQAGADISM	HSP90AA1	116	P07900
KVFMEVLQAGADISM	HSP90AA4P	56	Q58FG1
FDDTEEMQGFGVMQK	CRYBG1	1141	Q9Y4K1
VTQMVMGSTFEDDQE	CYP20A1	176	Q6UW02
MLSGTVTKVNETEMD	CREG1	151	O75629
DGKMVMTLTFGDVVA	FABP7	111	O15540
MGLETEKADVQLFMD	CAV2	1	P51636
SIMSFLDEMEKSGQD	CEP131	531	Q9UPN4
KAFMEALQAGADISM	HSP90AA2P	116	Q14568
KSTVIAMMTQEVEGE	PTPN13	2301	Q12923
MVAMAEAEAGVAVEV	PARP10	1	Q53GL7
KIQVSMMFDGQSAVE	LAMA4	831	Q16363
KSIIFNQDGTMTVEM	RP1	321	P56715
SESMKVVAESMGIAQ	TAF6	16	P49848
SVEEAENVMKFMNET	SYNE1	576	Q8NF91
SIMVTMENFSKEFEE	TMEM131L	261	A2VDJ0
MNGVRKDVVMTDSED	OGA	336	O60502
MEEVVNEFEPGMATK	SPATA31A7	1006	Q8IWB4
FMKDHFLMDEQVVGT	SEMA4A	391	Q9H3S1
MSMEDPFFVVKGEVQ	STX6	1	O43752
KEASDFVGMMLAAAT	SLC25A36	221	Q96CQ1
MFQTVDLFEGKDMAA	TAGLN	111	Q01995
QFMDNMSGGKVDEAL	MED13	1241	Q9UHV7
MAEGEKNQDFTFKME	SFR1	1	Q86XK3
EIMNSFAKSIEVMGD	RANBP6	776	O60518
AFSEALAEGAVKMGM	PYCR3	186	Q53H96
EVEKMGAVFMDAPVS	HIBADH	146	P31937
MAGMVDFQDEEQVKS	COA7	1	Q96BR5
GAVSKLMESMAAEED	TNRC18	2106	O15417
DMELSFAVQRGMDKV	MKRN3	296	Q13064
MEEVVNEFEPGMATK	SPATA31A1	1006	Q5TZJ5
MEEVVNEFEPGMATK	SPATA31A5	1006	Q5VU36
MGQTVNEDSMDVKKE	SCML2	1	Q9UQR0
VMDALSFVMGEKIAN	SMC1B	41	Q8NDV3
MVDMSEKGTEAGAAS	SERPINA11	361	Q86U17
TMIGKAVEHMFETED	SPIN1	131	Q9Y657
AFEEEMEAAMKGLVQ	SNX19	126	Q92543
SNFTKDMLMEGTEEV	TRIP11	31	Q15643
MGVKDFEENMNRSET	VPS13B	461	Q7Z7G8
ESVMENSKVLGESMA	TLN2	1396	Q9Y4G6
AASAIGMKMQDVDLF	SEPSECS	436	Q9HD40
ADSQAMVKIEDMAVS	ZKSCAN1	221	P17029
ADVVDVAADSMSGMT	PC	791	P11498
MAEEFVTLKDVGMDF	ZNF473	1	Q8WTR7
MNVGKVTDEMFLEAL	MYO1D	461	O94832
PSFKESEMNVIAADM	NACC2	426	Q96BF6