Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

SCUBE3 LTBP1 VWCE NOTCH1 CEMIP2 EGFL6 NOTCH4 CRB1

3.61e-05749358GO:0005509
GeneOntologyBiologicalProcesspositive regulation of aorta morphogenesis

NOTCH1 NOTCH4

1.58e-054342GO:1903849
GeneOntologyBiologicalProcessnegative regulation of glial cell differentiation

NR1D1 CASZ1 NOTCH1

3.59e-0539343GO:0045686
GeneOntologyBiologicalProcessregulation of aorta morphogenesis

NOTCH1 NOTCH4

3.94e-056342GO:1903847
GeneOntologyBiologicalProcesspositive regulation of transcription of Notch receptor target

NOTCH1 NOTCH4

5.51e-057342GO:0007221
GeneOntologyBiologicalProcessnegative regulation of photoreceptor cell differentiation

CASZ1 NOTCH1

5.51e-057342GO:0046533
GeneOntologyBiologicalProcessnegative regulation of cold-induced thermogenesis

ALDH1A1 NR1D1 NOTCH1

6.73e-0548343GO:0120163
GeneOntologyBiologicalProcessregulation of photoreceptor cell differentiation

CASZ1 NOTCH1

7.34e-058342GO:0046532
GeneOntologyBiologicalProcesspositive regulation of artery morphogenesis

NOTCH1 NOTCH4

9.43e-059342GO:1905653
GeneOntologyBiologicalProcessregulation of cold-induced thermogenesis

PPARGC1A ALDH1A1 NR1D1 NOTCH1

1.11e-04152344GO:0120161
GeneOntologyBiologicalProcessnegative regulation of cell-cell adhesion mediated by cadherin

NOTCH1 NOTCH4

1.18e-0410342GO:2000048
GeneOntologyBiologicalProcesscold-induced thermogenesis

PPARGC1A ALDH1A1 NR1D1 NOTCH1

1.22e-04156344GO:0106106
GeneOntologyBiologicalProcessnegative regulation of gliogenesis

NR1D1 CASZ1 NOTCH1

1.45e-0462343GO:0014014
GeneOntologyBiologicalProcesscamera-type eye morphogenesis

ALDH1A1 CASZ1 NOTCH1 CRB1

1.74e-04171344GO:0048593
GeneOntologyBiologicalProcessadaptive thermogenesis

PPARGC1A ALDH1A1 NR1D1 NOTCH1

1.95e-04176344GO:1990845
GeneOntologyBiologicalProcessinterleukin-17-mediated signaling pathway

TRAF5 NOTCH1

2.03e-0413342GO:0097400
GeneOntologyBiologicalProcessvenous blood vessel morphogenesis

NOTCH1 NOTCH4

2.03e-0413342GO:0048845
GeneOntologyBiologicalProcesseye photoreceptor cell differentiation

CASZ1 NOTCH1 CRB1

2.26e-0472343GO:0001754
GeneOntologyBiologicalProcesscellular response to follicle-stimulating hormone stimulus

PPARGC1A NOTCH1

2.73e-0415342GO:0071372
GeneOntologyBiologicalProcesstemperature homeostasis

PPARGC1A ALDH1A1 NR1D1 NOTCH1

2.93e-04196344GO:0001659
GeneOntologyBiologicalProcessaorta development

LTBP1 NOTCH1 NOTCH4

3.08e-0480343GO:0035904
GeneOntologyBiologicalProcessnegative regulation of cell adhesion molecule production

NOTCH1 NOTCH4

3.12e-0416342GO:0060354
GeneOntologyBiologicalProcesseye morphogenesis

ALDH1A1 CASZ1 NOTCH1 CRB1

3.41e-04204344GO:0048592
GeneOntologyBiologicalProcessregulation of artery morphogenesis

NOTCH1 NOTCH4

3.53e-0417342GO:1905651
GeneOntologyBiologicalProcessretina morphogenesis in camera-type eye

CASZ1 NOTCH1 CRB1

4.36e-0490343GO:0060042
GeneOntologyBiologicalProcessvenous blood vessel development

NOTCH1 NOTCH4

4.92e-0420342GO:0060841
GeneOntologyBiologicalProcessphotoreceptor cell differentiation

CASZ1 NOTCH1 CRB1

5.27e-0496343GO:0046530
GeneOntologyBiologicalProcessregulation of cell-cell adhesion mediated by cadherin

NOTCH1 NOTCH4

5.43e-0421342GO:2000047
GeneOntologyBiologicalProcessresponse to follicle-stimulating hormone

PPARGC1A NOTCH1

5.43e-0421342GO:0032354
GeneOntologyBiologicalProcesscellular response to gonadotropin stimulus

PPARGC1A NOTCH1

5.97e-0422342GO:0071371
GeneOntologyBiologicalProcessretinal cone cell differentiation

CASZ1 NOTCH1

5.97e-0422342GO:0042670
GeneOntologyBiologicalProcessneural retina development

CASZ1 NOTCH1 CRB1

6.29e-04102343GO:0003407
GeneOntologyBiologicalProcessregulation of cell adhesion molecule production

NOTCH1 NOTCH4

6.53e-0423342GO:0060353
GeneOntologyBiologicalProcessregulation of glial cell differentiation

NR1D1 CASZ1 NOTCH1

6.65e-04104343GO:0045685
GeneOntologyBiologicalProcessgliogenesis

NR1D1 CASZ1 NOTCH1 SUN1 CRB1

6.85e-04435345GO:0042063
GeneOntologyBiologicalProcesscellular response to interleukin-17

TRAF5 NOTCH1

7.12e-0424342GO:0097398
GeneOntologyBiologicalProcesscell adhesion molecule production

NOTCH1 NOTCH4

8.36e-0426342GO:0060352
GeneOntologyBiologicalProcessresponse to interleukin-17

TRAF5 NOTCH1

9.02e-0427342GO:0097396
GeneOntologyBiologicalProcesspositive regulation of smooth muscle cell differentiation

NOTCH1 NOTCH4

9.71e-0428342GO:0051152
GeneOntologyBiologicalProcesscellular response to hormone stimulus

PPARGC1A MBD5 NR1D1 NOTCH1 PCSK9 INSRR

1.09e-03727346GO:0032870
GeneOntologyBiologicalProcessprotein autoprocessing

MYRFL PCSK9

1.11e-0330342GO:0016540
GeneOntologyCellularComponentCD40 receptor complex

TRAF5 RNF31

1.48e-0411352GO:0035631
MousePhenodecreased circulating total protein level

SCUBE3 LTBP1 SUN1 PEAR1 ZNF558

8.65e-06162255MP:0005567
DomainGrowth_fac_rcpt_

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1 INSRR

3.84e-10156358IPR009030
DomainEGF_Ca-bd_CS

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1

4.88e-1097357IPR018097
DomainEGF_CA

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1

5.65e-1099357PS01187
DomainASX_HYDROXYL

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1

6.06e-10100357PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1

9.16e-10106357IPR000152
DomainEGF_CA

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1

2.46e-09122357SM00179
DomainEGF-like_Ca-bd_dom

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1

2.76e-09124357IPR001881
DomainEGF_3

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1 PEAR1

9.79e-09235358PS50026
DomainEGF

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1 PEAR1

9.79e-09235358SM00181
DomainEGF_CA

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4

1.16e-0886356PF07645
DomainEGF-like_dom

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1 PEAR1

1.54e-08249358IPR000742
DomainEGF_1

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1 PEAR1

1.85e-08255358PS00022
DomainEGF-like_CS

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1 PEAR1

2.22e-08261358IPR013032
DomainEGF_2

SCUBE3 LTBP1 VWCE NOTCH1 EGFL6 NOTCH4 CRB1 PEAR1

2.50e-08265358PS01186
DomainEGF

SCUBE3 LTBP1 NOTCH1 NOTCH4 CRB1

3.56e-06126355PF00008
DomainhEGF

NOTCH1 NOTCH4 CRB1

1.91e-0528353PF12661
DomainNOD

NOTCH1 NOTCH4

2.04e-054352PF06816
DomainNotch

NOTCH1 NOTCH4

2.04e-054352IPR008297
DomainNODP

NOTCH1 NOTCH4

2.04e-054352PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH4

2.04e-054352IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH4

2.04e-054352IPR010660
DomainNOD

NOTCH1 NOTCH4

2.04e-054352SM01338
DomainNODP

NOTCH1 NOTCH4

2.04e-054352SM01339
DomainLNR

NOTCH1 NOTCH4

3.40e-055352PS50258
DomainNotch_dom

NOTCH1 NOTCH4

7.12e-057352IPR000800
DomainNotch

NOTCH1 NOTCH4

7.12e-057352PF00066
DomainNL

NOTCH1 NOTCH4

7.12e-057352SM00004
DomaincEGF

SCUBE3 LTBP1

1.08e-0326352IPR026823
DomaincEGF

SCUBE3 LTBP1

1.08e-0326352PF12662
DomainVWC

VWCE PXDNL

1.25e-0328352PF00093
DomainVWFC_1

VWCE PXDNL

2.07e-0336352PS01208
DomainVWC

VWCE PXDNL

2.30e-0338352SM00214
DomainVWFC_2

VWCE PXDNL

2.30e-0338352PS50184
DomainVWF_dom

VWCE PXDNL

2.80e-0342352IPR001007
DomainZnf_RING_CS

TRAF5 RNF31 RNF17

3.48e-03163353IPR017907
DomainCUB

SCUBE3 NETO2

3.80e-0349352PF00431
DomainCUB

SCUBE3 NETO2

3.95e-0350352SM00042
Domain-

SCUBE3 NETO2

4.27e-03523522.60.120.290
DomainCUB

SCUBE3 NETO2

4.43e-0353352PS01180
DomainCUB_dom

SCUBE3 NETO2

5.10e-0357352IPR000859
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH4

1.91e-055202M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH4

1.91e-055202MM14733
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH4

2.86e-056202M27068
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH4

4.00e-057202MM14734
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH4

1.04e-0411202M47865
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH4

1.25e-0412202M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH4

1.25e-0412202M47533
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH4

1.48e-0413202M47423
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH1 NOTCH4

1.48e-0413202M47534
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH4

2.27e-0416202M47424
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH4

2.89e-0418202M614
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH4

3.58e-0420202M27881
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH4

4.75e-0423202MM14954
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH4

5.18e-0424202M11190
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

NOTCH1 NOTCH4

6.57e-0427202M39545
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH4

7.07e-0428202M6177
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH1 NOTCH4

1.04e-0334202M39390
PathwayWP_GENETIC_CAUSES_OF_PORTOSINUSOIDAL_VASCULAR_DISEASE

NOTCH1 NOTCH4

1.24e-0337202M45513
PathwayWP_NEOVASCULARIZATION_PROCESSES

NOTCH1 NOTCH4

1.24e-0337202M39506
PathwayREACTOME_SIGNALING_BY_NOTCH

NOTCH1 NOTCH4

1.37e-0339202MM14604
PathwayWP_NOTCH_SIGNALING_WP268

NOTCH1 NOTCH4

1.83e-0345202M39571
PathwayWP_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH4

1.91e-0346202MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

NOTCH1 NOTCH4

1.99e-0347202M7946
PathwayREACTOME_HEME_SIGNALING

PPARGC1A NR1D1

2.16e-0349202M41832
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVATION_OF_MITOCHONDRIAL_BIOGENESIS

PPARGC1A NR1D1

2.71e-0355202M27145
PathwayPID_NOTCH_PATHWAY

NOTCH1 NOTCH4

3.12e-0359202M17
PathwayWP_NOTCH_SIGNALING_WP61

NOTCH1 NOTCH4

3.33e-0361202M39540
PathwayWP_PATHWAYS_AFFECTED_IN_ADENOID_CYSTIC_CARCINOMA

NOTCH1 INSRR

3.77e-0365202M39682
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

NOTCH1 NOTCH4

4.12e-0368202M27303
Pubmed

Introduction to Notch signaling.

NOTCH1 NOTCH4

1.04e-06236225053477
Pubmed

Differential patterns of NOTCH1-4 receptor expression are markers of glioma cell differentiation.

NOTCH1 NOTCH4

1.04e-06236224305720
Pubmed

Notch signaling in cancer.

NOTCH1 NOTCH4

1.04e-06236212496471
Pubmed

Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy.

NOTCH1 NOTCH4

1.04e-06236223389453
Pubmed

Notch signaling: from the outside in.

NOTCH1 NOTCH4

1.04e-06236211112321
Pubmed

Clinicopathological significance of aberrant Notch receptors in intrahepatic cholangiocarcinoma.

NOTCH1 NOTCH4

1.04e-06236225031748
Pubmed

Thymosin beta4 induces angiogenesis through Notch signaling in endothelial cells.

NOTCH1 NOTCH4

1.04e-06236223749167
Pubmed

Critical role of endothelial Notch1 signaling in postnatal angiogenesis.

NOTCH1 NOTCH4

1.04e-06236217158336
Pubmed

Notch-1 and Notch-4 biomarker expression in triple-negative breast cancer.

NOTCH1 NOTCH4

1.04e-06236222084425
Pubmed

Notch-1 and notch-4 receptors as prognostic markers in breast cancer.

NOTCH1 NOTCH4

1.04e-06236220444726
Pubmed

PGC-1α Protects from Notch-Induced Kidney Fibrosis Development.

PPARGC1A NOTCH1

1.04e-06236228751525
Pubmed

Notch1 and Notch4 are markers for poor prognosis of hepatocellular carcinoma.

NOTCH1 NOTCH4

1.04e-06236223742774
Pubmed

Hepatitis B virus X protein activates Notch signaling by its effects on Notch1 and Notch4 in human hepatocellular carcinoma.

NOTCH1 NOTCH4

1.04e-06236226530164
Pubmed

Notch receptor expression in human brain arteriovenous malformations.

NOTCH1 NOTCH4

3.12e-06336225846406
Pubmed

Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches.

NOTCH1 NOTCH4

3.12e-06336218593923
Pubmed

Characterization of Notch Signalling Pathway Members in Normal Prostate, Prostatic Intraepithelial Neoplasia (PIN) and Prostatic Adenocarcinoma.

NOTCH1 NOTCH4

3.12e-06336226341090
Pubmed

Differential expression of Notch genes in human osteoblastic cells.

NOTCH1 NOTCH4

3.12e-06336211836628
Pubmed

Notch activation results in phenotypic and functional changes consistent with endothelial-to-mesenchymal transformation.

NOTCH1 NOTCH4

3.12e-06336214988227
Pubmed

Delta-like 4/Notch pathway is differentially regulated in benign and malignant thyroid tissues.

NOTCH1 NOTCH4

3.12e-06336222066479
Pubmed

Unique patterns of Notch1, Notch4 and Jagged1 expression in ovarian vessels during folliculogenesis and corpus luteum formation.

NOTCH1 NOTCH4

3.12e-06336215939383
Pubmed

Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease.

NOTCH1 NOTCH4

3.12e-06336219546852
Pubmed

PGC-1alpha negatively regulates hepatic FGF21 expression by modulating the heme/Rev-Erb(alpha) axis.

PPARGC1A NR1D1

3.12e-06336220018698
Pubmed

NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications.

NOTCH1 NOTCH4

3.12e-06336221679465
Pubmed

Notch signaling: cell fate control and signal integration in development.

NOTCH1 NOTCH4

3.12e-06336210221902
Pubmed

Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.

NOTCH1 NOTCH4

3.12e-06336228871079
Pubmed

Notch1 is pan-endothelial at the onset of flow and regulated by flow.

NOTCH1 NOTCH4

3.12e-06336225830332
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH1 NOTCH4

6.24e-06436228061457
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH1 NOTCH4

6.24e-06436224145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH1 NOTCH4

6.24e-06436220069356
Pubmed

ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds.

NOTCH1 NOTCH4

6.24e-06436227354212
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH1 NOTCH4

6.24e-06436219404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH1 NOTCH4

6.24e-06436228669409
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH1 NOTCH4

6.24e-06436211466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH1 NOTCH4

6.24e-06436224151014
Pubmed

Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin.

NOTCH1 NOTCH4

6.24e-06436217984306
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH1 NOTCH4

6.24e-06436211401408
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH1 NOTCH4

6.24e-06436210194420
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH1 NOTCH4

6.24e-0643628898100
Pubmed

Notch1 and Notch4 core binding domain peptibodies exhibit distinct ligand-binding and anti-angiogenic properties.

NOTCH1 NOTCH4

6.24e-06436236376768
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH1 NOTCH4

6.24e-06436211459941
Pubmed

Notch1 deficiency results in decreased inflammation during wound healing and regulates vascular endothelial growth factor receptor-1 and inflammatory cytokine expression in macrophages.

NOTCH1 NOTCH4

6.24e-06436220739676
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH1 NOTCH4

6.24e-06436218184405
Pubmed

Expression of NOTCH1, NOTCH4, HLA-DMA and HLA-DRA is synergistically associated with T cell exclusion, immune checkpoint blockade efficacy and recurrence risk in ER-negative breast cancer.

NOTCH1 NOTCH4

6.24e-06436235543859
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH1 NOTCH4

6.24e-06436215917835
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH1 NOTCH4

6.24e-06436223444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH1 NOTCH4

6.24e-06436217920003
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH1 NOTCH4

1.04e-05536221124806
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH1 NOTCH4

1.04e-05536223675950
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH1 NOTCH4

1.04e-05536211101851
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH1 NOTCH4

1.04e-05536215882997
Pubmed

Association of Notch pathway down-regulation with Triple Negative/Basal-like breast carcinomas and high tumor-infiltrating FOXP3+ Tregs.

NOTCH1 NOTCH4

1.04e-05536227118257
Pubmed

Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.

NOTCH1 NOTCH4

1.04e-05536220554499
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH1 NOTCH4

1.56e-0563629111338
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH1 NOTCH4

1.56e-05636220870902
Pubmed

A study on Notch signaling in human breast cancer.

NOTCH1 NOTCH4

1.56e-05636217822320
Pubmed

ALDH maintains the stemness of lung adenoma stem cells by suppressing the Notch/CDK2/CCNE pathway.

ALDH1A1 NOTCH1

1.56e-05636224671051
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH1 NOTCH4

1.56e-05636212244553
Pubmed

Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site.

NOTCH1 NOTCH4

1.56e-05636218239137
Pubmed

Notch4 Negatively Regulates the Inflammatory Response to Mycobacterium tuberculosis Infection by Inhibiting TAK1 Activation.

NOTCH1 NOTCH4

1.56e-05636229228365
Pubmed

Epidermal growth factor-like domain 7 (EGFL7) modulates Notch signalling and affects neural stem cell renewal.

NOTCH1 NOTCH4

1.56e-05636219503073
Pubmed

Three genes in the human MHC class III region near the junction with the class II: gene for receptor of advanced glycosylation end products, PBX2 homeobox gene and a notch homolog, human counterpart of mouse mammary tumor gene int-3.

NOTCH1 NOTCH4

1.56e-0563627835890
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH1 NOTCH4

1.56e-05636218299578
Pubmed

Notch4 reveals a novel mechanism regulating Notch signal transduction.

NOTCH1 NOTCH4

1.56e-05636224667410
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH1 NOTCH4

1.56e-05636215019995
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH1 NOTCH4

1.56e-05636222615412
Pubmed

Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.

NOTCH1 NOTCH4

1.56e-05636221991352
Pubmed

CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.

PPARGC1A ALDH1A1 NR1D1 NOTCH1

1.58e-0514636429688375
Pubmed

Six1 homeoprotein drives myofiber type IIA specialization in soleus muscle.

PPARGC1A ALDH1A1 NR1D1

1.93e-055036327597886
Pubmed

Hepatitis B Virus-Induced Parkin-Dependent Recruitment of Linear Ubiquitin Assembly Complex (LUBAC) to Mitochondria and Attenuation of Innate Immunity.

TRAF5 RNF31

2.18e-05736227348524
Pubmed

Human ligands of the Notch receptor.

NOTCH1 NOTCH4

2.18e-05736210079256
Pubmed

Artery and vein size is balanced by Notch and ephrin B2/EphB4 during angiogenesis.

NOTCH1 NOTCH4

2.18e-05736218952909
Pubmed

Notch signaling functions in lymphatic valve formation.

NOTCH1 NOTCH4

2.18e-05736224917500
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

NOTCH1 NOTCH4

2.18e-05736212846471
Pubmed

Murine notch homologs (N1-4) undergo presenilin-dependent proteolysis.

NOTCH1 NOTCH4

2.18e-05736211518718
Pubmed

SEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradation.

NOTCH1 NOTCH4

2.18e-05736211585921
Pubmed

Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse.

TYRP1 ALDH1A1 NOTCH1

2.30e-05533637774911
Pubmed

Slug is a direct Notch target required for initiation of cardiac cushion cellularization.

NOTCH1 NOTCH4

2.91e-05836218663143
Pubmed

Cranial neural crest ablation of Jagged1 recapitulates the craniofacial phenotype of Alagille syndrome patients.

NOTCH1 NOTCH4

2.91e-05836222156581
Pubmed

Notch1 and Jagged1 expression by the developing pulmonary vasculature.

NOTCH1 NOTCH4

2.91e-05836212242716
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

NOTCH1 NOTCH4

2.91e-0583629858718
Pubmed

Notch signaling represses p63 expression in the developing surface ectoderm.

NOTCH1 NOTCH4

3.73e-05936223924630
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

NOTCH1 NOTCH4

3.73e-05936211118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

NOTCH1 NOTCH4

3.73e-05936216245338
Pubmed

Identification of a family of mastermind-like transcriptional coactivators for mammalian notch receptors.

NOTCH1 NOTCH4

3.73e-05936212370315
Pubmed

Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.

NOTCH1 NOTCH4

3.73e-05936217948123
Pubmed

Divergent vascular mechanisms downstream of Sry establish the arterial system in the XY gonad.

NOTCH1 NOTCH4

3.73e-05936211944948
Pubmed

Notch signaling is essential for vascular morphogenesis in mice.

NOTCH1 NOTCH4

3.73e-05936210837027
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

NOTCH1 NOTCH4

4.66e-051036223665443
Pubmed

Maternal Cripto is required for proper uterine decidualization and peri-implantation uterine remodeling.

NOTCH1 NOTCH4

4.66e-051036233590845
Pubmed

Unique functions for Notch4 in murine embryonic lymphangiogenesis.

NOTCH1 NOTCH4

4.66e-051036234665379
Pubmed

Defective cardiovascular development and elevated cyclin E and Notch proteins in mice lacking the Fbw7 F-box protein.

NOTCH1 NOTCH4

4.66e-051036214766969
Pubmed

Notch4 signaling limits regulatory T-cell-mediated tissue repair and promotes severe lung inflammation in viral infections.

NOTCH1 NOTCH4

4.66e-051036233915108
Pubmed

Jag2-Notch1 signaling regulates oral epithelial differentiation and palate development.

NOTCH1 NOTCH4

5.70e-051136216607638
Pubmed

The expression of Sox17 identifies and regulates haemogenic endothelium.

NOTCH1 NOTCH4

5.70e-051136223604320
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

NOTCH1 NOTCH4

5.70e-051136215499562
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

NOTCH1 NOTCH4

5.70e-051136210878608
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

NOTCH1 NOTCH4

5.70e-05113629187150
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

NOTCH1 NOTCH4

5.70e-051136212866128
Pubmed

Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium.

NOTCH1 NOTCH4

6.83e-051236210952889
Pubmed

Impaired angiogenesis and altered Notch signaling in mice overexpressing endothelial Egfl7.

NOTCH1 NOTCH4

6.83e-051236220947685
Cytoband9q21.13

ALDH1A1 CEMIP2

1.77e-04253629q21.13
GeneFamilyRing finger proteins

TRAF5 RNF31 RNF17

3.78e-0327521358
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF749 CASZ1 ZNF558 ZNF646

8.61e-0371821428
GeneFamilyAnkyrin repeat domain containing

NOTCH1 NOTCH4

3.17e-02242212403
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TYRP1 LTBP1 ALDH1A1 CASZ1

7.96e-06163354e526104a3a574ee860078ce7c049e7fec9443f37
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CASZ1 NOTCH1 CEMIP2 NOTCH4

1.03e-05174354b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASZ1 NOTCH1 CEMIP2 NOTCH4

1.08e-05176354269326c2bf44a9003d95bc6dbc839f08f25737ca
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NETO2 NOTCH1 CEMIP2 NOTCH4

1.20e-051813544d7793026373cbcf04b15c77f95f1025d07d4c00
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALDH1A1 NOTCH1 CEMIP2 CRB1

1.20e-05181354f2ebeb4941510c4b6e50f2379c574d1778d6ced1
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TYRP1 PPARGC1A LTBP1 NR1D1

1.26e-05183354a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NETO2 NOTCH1 CEMIP2 NOTCH4

1.26e-051833543427f3cbe6ea81709750e7dd3ff378f03ae65eab
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALDH1A1 NOTCH1 CEMIP2 CRB1

1.28e-051843547712f2e1fae5cdde2d4e355b860dc8536b28e4f6
ToppCellPericytes-HP_01|World / lung cells shred on cell class, cell subclass, sample id

SCUBE3 LTBP1 MYRFL EGFL6

1.37e-0518735435f25780d113f60bf4c13749013c09612ee4ff41
ToppCellP03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NETO2 NOTCH1 CEMIP2 NOTCH4

1.37e-0518735466ebe1788d51b3e17bec6cdb219f709756b4e530
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TYRP1 LTBP1 TRAF5 PXDNL

1.40e-05188354f54b063025d80de631382bf5326bc40aab7f7d00
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TYRP1 LTBP1 TRAF5 CASZ1

1.40e-0518835474f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TYRP1 LTBP1 TRAF5 CASZ1

1.40e-051883543004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCellPND07-28-samps-Endothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CASZ1 NOTCH1 CEMIP2 NOTCH4

1.43e-05189354eb2f8c8a90e5e9f6697a2d13274c94f40e1973e4
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASZ1 NOTCH1 CEMIP2 NOTCH4

1.43e-051893541e1afa66b32ae752c0a42b02b80f10205464569c
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CASZ1 NOTCH1 CEMIP2 NOTCH4

1.43e-05189354d4a25d59d88325d3b20f4287e9b1160c82961a96
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TYRP1 LTBP1 TRAF5 PXDNL

1.46e-05190354938d1f66094b1c94606e0d40213a39e5112f3322
ToppCellfacs-Lung-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CASZ1 NOTCH1 CEMIP2 NOTCH4

1.46e-05190354d55b3ad4d1ec172b042bc08127506c354f87f69d
ToppCellPND10-Endothelial-Endothelial_blood-vessel|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASZ1 NOTCH1 CEMIP2 NOTCH4

1.55e-051933541d8acf81dcbfe81c7a73ce50c9f38fe0cbc74486
ToppCellPND10-Endothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASZ1 NOTCH1 CEMIP2 NOTCH4

1.55e-05193354f3c743b340fc588bc8effd375b12e2c7cbfa49d2
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALDH1A1 NOTCH1 CEMIP2 CRB1

1.55e-05193354cdc44bf6f5436eb8a2d4720fe011dcb85ccecf87
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASZ1 NOTCH1 CEMIP2 NOTCH4

1.58e-051943541b382508453c5b08fb617f626b230adf3b6cff99
ToppCelldroplet-Bladder-nan-3m-Epithelial-luminal_bladder_epithelial_cell_(umbrella_cell)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A CASZ1 NOTCH1 UPK3B

1.61e-05195354d6e2a5a15bea16de5f7ff09318c67d46ea923203
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TYRP1 LTBP1 TRAF5 ALDH1A1

1.61e-051953548a04f0e92d10a368ccda5f566ae67ef51f1d34a9
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASZ1 NOTCH1 CEMIP2 NOTCH4

1.61e-05195354cd011433b3b9bfb1adb13eca2f3f2a5db024cd94
ToppCellPericytes|World / shred by cell class for parenchyma

SCUBE3 LTBP1 MYRFL EGFL6

1.65e-051963548e7ecbe77d312a7fc6aadd8fd52c13dd1834cc7e
ToppCell(5)_Fibroblast-K_(Pericytes)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

SCUBE3 LTBP1 MYRFL EGFL6

1.65e-05196354e3c89c5bd674289738d5590ebfd30c605f5156a5
ToppCellASK454-Endothelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

CASZ1 CEMIP2 NOTCH4 PEAR1

1.65e-0519635414dd6956ef420b660be0baf52a66960e57d75d16
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOTCH1 CEMIP2 CRB1 ZDHHC22

1.68e-051973541378bf90a4b80b8166ef352c282ce51b114ba693
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)|343B / Donor, Lineage, Cell class and subclass (all cells)

SCUBE3 LTBP1 MYRFL EGFL6

1.68e-0519735478d45d11820ec379942c4c3defd619d5f8cc8e1f
ToppCell343B-Fibroblasts-Fibroblast-K_(Pericytes)-|343B / Donor, Lineage, Cell class and subclass (all cells)

SCUBE3 LTBP1 MYRFL EGFL6

1.68e-0519735431bc9fd679d78550541d4158568e8dd09ff29e8e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TYRP1 LTBP1 TRAF5 ALDH1A1

1.68e-051973545a63c2b824c7d0dbbc706e408459c9b9fe65daaa
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TYRP1 LTBP1 TRAF5 EGFL6

1.71e-05198354637f11e292b90d86cdc0d0d828eb26f38289c25b
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NOTCH1 CEMIP2 CRB1 ZDHHC22

1.71e-05198354c506334d81af672ef9ddc8c4fd2a790bdb58e63e
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SCUBE3 LTBP1 PCSK9 PEAR1

1.75e-05199354fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TYRP1 LTBP1 PXDNL EGFL6

1.75e-05199354aacd3ffa40a6e6f435aa9be5b959d88812eb69d4
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ALDH1A1 ARSD CASZ1 SUN1

1.78e-0520035497f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

LTBP1 ALDH1A1 PXDNL CEMIP2

1.78e-05200354a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ALDH1A1 ARSD CASZ1 SUN1

1.78e-05200354ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Trh_(Substantia_Innominata_(SI))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

POF1B CRB1 INSRR

3.66e-058235315bc417aaace2b1d680904a622fe76e95083c9ff
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Trh_(Substantia_Innominata_(SI))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

POF1B CRB1 INSRR

3.66e-0582353697e1da3095c8483b8181b290fa5417bdc9cee54
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Trh_(Substantia_Innominata_(SI))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

POF1B CRB1 INSRR

3.66e-058235373349906bcc8d1a40dc03df7a490a963e85564f2
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high|E18.5-samps / Age Group, Lineage, Cell class and subclass

CASZ1 PCSK9 UPK3B

2.38e-04154353212c340a096a3a9669d1aebd61c045cf1402a868
ToppCellTCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Serous_adenocarcinoma|TCGA-Endometrium / Sample_Type by Project: Shred V9

PPARGC1A EGFL6 UPK3B

2.86e-0416435308c725548e751f815b4df778607270498204b353
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

TYRP1 LTBP1 PXDNL

2.86e-04164353e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPARGC1A LTBP1 ALDH1A1

2.91e-04165353b1bbf5acdfc52bd8c7c7eb356d73b812eb6b908c
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPARGC1A LTBP1 ALDH1A1

2.91e-0416535328f8297ec7b781149cc7ac2f5e441771083b8ee3
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NOTCH1 CEMIP2 NOTCH4

2.96e-041663537a45785a40b7425f97be67bab1c5ceb69b2bd85a
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NOTCH1 CEMIP2 NOTCH4

2.96e-04166353bbd382812f8a84a5d99888de2d7cca3a8b5e4695
ToppCellfacs-Aorta-Heart-3m-Endothelial-endocardial_endothelial_cells|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEMIP2 PEAR1 ZDHHC22

3.01e-04167353a4a795751644b22af616335379e64ae95175180c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALDH1A1 CRB1 ZDHHC22

3.01e-0416735317c653b46507c8bb85da95836ae72a6015336142
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LTBP1 TRAF5 ALDH1A1

3.07e-0416835374d6dbf9295933acdee785af9b73a94377d15412
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRR14L NR1D1 EGFL6

3.07e-0416835308f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Endothelial-new-cluster|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 CEMIP2 NOTCH4

3.17e-041703534fb4ce46e4fa2418238e264875209d7ebe844d82
ToppCellNasal_Brush-Epithelial-Basal_1|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

TRAF5 NETO2 NOTCH4

3.28e-041723534483073469001770015526303772fd54906c5d68
ToppCellNasal_Brush-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

TRAF5 NETO2 NOTCH4

3.28e-0417235358eaadf12366701103a0d1f133462c9495fedc30
ToppCellASK440-Epithelial-Transformed_epithelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

EGFL6 UPK3B ZNF558

3.28e-04172353df3800bcd9777d02900eba0cfc26ab73de8a1d95
ToppCellfacs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NOTCH1 NOTCH4 CRB1

3.28e-04172353c84cab89c97d647b8a256fd08e33d9102810febd
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LTBP1 PCSK9 UPK3B

3.34e-041733533725525b99a6011eda2ff5459b4fd2e1eab1f090
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LTBP1 PCSK9 UPK3B

3.34e-04173353ee7d1429f23f1b89a9a9f7bc07a84a44cf7acd1c
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Endothelial-endothelial_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 CEMIP2 NOTCH4

3.34e-041733532a5ea28c65dd4ee03ba3d0bfe0c819b1d583f8da
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Endothelial|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 CEMIP2 NOTCH4

3.34e-041733536a7e4fa2d9d00f50decc89b535d8a68ec96de58a
ToppCell(6)_Endothelial_cells-(6)_Endothelial-E|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

CASZ1 CEMIP2 NOTCH4

3.40e-041743534a1b67ce5ea353b3f81f59fa57da07668146afca
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-3|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCUBE3 POF1B PEAR1

3.40e-0417435376310c0af1d7df6a4de3816838b2ac2892f68746
ToppCellfacs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOTCH1 CEMIP2 CRB1

3.40e-0417435342dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCellfacs-Heart-RA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOTCH1 CEMIP2 CRB1

3.40e-04174353f04edf2ca6788875c9918611e416fb739924382e
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ALDH1A1 PCSK9 UPK3B

3.40e-041743534da79da7a09ee1e345102c5331675ebcdbe56171
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALDH1A1 CRB1 ZDHHC22

3.40e-04174353412ccc099028a372b9d953363984c2da54b2187f
ToppCellfacs-Lung-Endomucin-24m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 NOTCH1 CEMIP2

3.45e-04175353eedb33e3e350169d1d37f2ac9939dcf704e7b696
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR1D1 CASZ1 CEMIP2

3.45e-04175353cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCellE16.5-Epithelial-Epithelial_Airway-Neurosecretory|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ALDH1A1 MYRFL POF1B

3.45e-0417535338dec78efc99fe23479cba68cfa441e62bd6a08b
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

TYRP1 LTBP1 EGFL6

3.45e-04175353fed9e4120c758fdcc23bb248d1801002b0e0d485
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASZ1 NOTCH1 CEMIP2

3.45e-041753531c7725f917f3d6b9e0a31ede9524690f408a5ea1
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neuron_precursor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALDH1A1 CRB1 ZDHHC22

3.45e-041753532ce8bcf9926862e723219b4246388428d0c3fdee
ToppCellPericytes-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

TYRP1 LTBP1 EGFL6

3.45e-04175353ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LTBP1 PCSK9 UPK3B

3.51e-041763538e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LTBP1 PCSK9 UPK3B

3.51e-04176353ed575330a08a6748ea4b28433292c8cfd157d444
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ALDH1A1 MBD5 PXDNL

3.57e-04177353b7fee75de7e96924af488a5baa2334711889ae7c
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-neuron_precursor-Neuroblast|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALDH1A1 CEMIP2 CRB1

3.57e-041773536f3b254e56e722cc23495b49e99a4abce0243cb3
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

LTBP1 NOTCH4 ZNF558

3.57e-04177353eb0cfe8e9a91910f9979608ed47add48d98ce4dd
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALDH1A1 VWCE EGFL6

3.57e-041773537af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell368C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LTBP1 NOTCH4 ZNF558

3.63e-041783539d575902d3dbe33437c9d4200df093a741269803
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PPARGC1A PXDNL EGFL6

3.63e-04178353066dbc4cc2083c549d98122ed44707127f34d582
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SCUBE3 PPARGC1A CASZ1

3.69e-04179353666072c0e8448dbaec1683d18368ec2502453f90
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPARGC1A CASZ1 EGFL6

3.75e-041803530b653b1b653b40f3b8711d1312029a4a8a4961db
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CASZ1 CEMIP2 NOTCH4

3.81e-041813539cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCelldroplet-Liver-Npc-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEMIP2 NOTCH4 PEAR1

3.87e-04182353dc55de945c6f78f32eb3a1b3520835eb8417e068
ToppCellPericytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

LTBP1 MYRFL EGFL6

3.87e-0418235346c213597445b1f4f09dc367f27702d24b201daf
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NETO2 NOTCH1 NOTCH4

3.87e-041823530346f81bbb1f309f3e9d063b20547d548d09472c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCUBE3 PPARGC1A CASZ1

3.87e-041823535f513bbb7125956eb528e3120de3fd776770a7c3
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEMIP2 NOTCH4 PEAR1

3.87e-04182353010a7364da46101cb5068891fd7bc712ea8f13bd
ToppCelldroplet-Liver-Npc-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CEMIP2 NOTCH4 PEAR1

3.87e-04182353b1ec2015aad1181eac1bbf8d48ad6f2f7ed24a01
ToppCellPericytes-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

SCUBE3 LTBP1 MYRFL

3.94e-04183353d04deef7cd4e1738227a6593b84874ce0168c773
ToppCellPericytes-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

LTBP1 MYRFL EGFL6

3.94e-041833534617b18da8d699a44e4c47980197b1e7eb951470
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPARGC1A LTBP1 ALDH1A1

3.94e-04183353262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PPARGC1A LTBP1 ALDH1A1

3.94e-04183353c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L5-6_LAMP5_SFTA3_(Lamp5_Lhx6_2)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LTBP1 MYRFL EGFL6

4.00e-04184353e2de27cee3ea80f9b7a9a7884ceceeaa67b3214a
ToppCell5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ALDH1A1 EGFL6 PEAR1

4.00e-041843534d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCellAdult-Endothelial-capillary_endothelial_cell_(Cap1)-D231|Adult / Lineage, Cell type, age group and donor

CASZ1 CEMIP2 NOTCH4

4.06e-0418535307f9f38f0739d7c830641723a38385550ac1ac92
ToppCelldroplet-Heart-nan-18m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOTCH1 CEMIP2 NOTCH4

4.06e-04185353a32d5cb596ebac80eb1ac301055e65d420879ec8
Diseasehemangiopericytoma (is_marker_for)

NOTCH1 NOTCH4

4.08e-059322DOID:264 (is_marker_for)
Diseaseobesity (implicated_via_orthology)

PPARGC1A ALDH1A1 NOTCH1 NOTCH4

8.40e-05215324DOID:9970 (implicated_via_orthology)
Diseasefacial morphology measurement

TYRP1 PPARGC1A PXDNL CASZ1 CRB1

1.36e-04466325EFO_0007841
DiseaseAdenoid Cystic Carcinoma

NETO2 NOTCH1 INSRR

1.74e-04100323C0010606
DiseaseCarcinoma, Pancreatic Ductal

NOTCH1 NOTCH4

3.10e-0424322C0887833
Diseasehyperthyroidism (biomarker_via_orthology)

PPARGC1A NR1D1

4.23e-0428322DOID:7998 (biomarker_via_orthology)
Diseaselupus nephritis

NOTCH4 CRB1

5.89e-0433322EFO_0005761
DiseaseParoxysmal atrial fibrillation

MBD5 CASZ1 SUN1

6.42e-04156323C0235480
Diseasefamilial atrial fibrillation

MBD5 CASZ1 SUN1

6.42e-04156323C3468561
DiseasePersistent atrial fibrillation

MBD5 CASZ1 SUN1

6.42e-04156323C2585653
Diseaseendometrial cancer (is_marker_for)

NOTCH1 NOTCH4

6.63e-0435322DOID:1380 (is_marker_for)
DiseaseAtrial Fibrillation

MBD5 CASZ1 SUN1

6.91e-04160323C0004238
Diseaseblood urea nitrogen measurement

PPARGC1A TRAF5 MBD5 CASZ1

1.39e-03452324EFO_0004741
Diseasefeeling emotionally hurt measurement

MBD5 CRB1

1.69e-0356322EFO_0009599
DiseaseAlzheimer's disease (implicated_via_orthology)

PPARGC1A NOTCH4

1.75e-0357322DOID:10652 (implicated_via_orthology)
DiseaseFEV/FEC ratio

SCUBE3 PPARGC1A LTBP1 CAPZA3 MYRFL CEMIP2

1.83e-031228326EFO_0004713
DiseaseMalignant neoplasm of skin

NOTCH1 NOTCH4

1.88e-0359322C0007114
DiseaseSkin Neoplasms

NOTCH1 NOTCH4

1.88e-0359322C0037286
Diseasepolychlorinated biphenyls measurement

MBD5 INSRR

2.27e-0365322EFO_0007042
DiseaseQT interval

PPARGC1A MBD5 CASZ1 NOTCH4

2.55e-03534324EFO_0004682
Diseaseneuroticism measurement

PPARGC1A MBD5 NOTCH4 CRB1 ZNF646

2.77e-03909325EFO_0007660
Diseasefeeling nervous measurement

MBD5 NOTCH4

4.02e-0387322EFO_0009597

Protein segments in the cluster

PeptideGeneStartEntry
HQGECAGHQHCQKYS

CAPZA3

46

Q96KX2
QGVNCASRGDHCHHP

ARSD

151

P51689
DSHTCSHHANCFNTQ

EGFL6

226

Q8IUX8
FSGSQHCGHIHCAYQ

CASZ1

471

Q86V15
AHHGVFYHQGQCCIA

ALDH1A1

291

P00352
CQHGGLCVDAGNTHH

NOTCH1

1116

P46531
HCHQQGHVLTGCSSH

PCSK9

551

Q8NBP7
HRHLCAHGQCRNTEG

LTBP1

1126

Q14766
HWGENCAQTCQCHHG

PEAR1

656

Q5VY43
CQIHGGFHSCHSNAS

MYRFL

111

Q96LU7
GHDHGCHQQPRICNA

PMS2P11

131

Q13670
LNTDQGCHPQAQCHH

POF1B

176

Q8WVV4
CSGLSTQNHANHNHR

PPARGC1A

161

Q9UBK2
HSCHQSNSNGHRLCP

NR1D1

376

P20393
RDHGRFTCHANNSHG

PXDNL

391

A1KZ92
SHRHGHSYCSSQGCE

CEMIP2

1136

Q9UHN6
GEAVHCHNANTNFVH

MBD5

756

Q9P267
DIHACNHAAHTVGCS

INSRR

786

P14616
HQCANGATCISHTNG

CRB1

1221

P82279
HNGNSTNSNHCHEAA

SCUBE3

461

Q8IX30
NAFQHRDHCCQGTGH

PRR14L

826

Q5THK1
ASRCIHDHHCGSQAS

NETO2

431

Q8NC67
DHFHNGHCEKGCNTA

NOTCH4

1261

Q99466
HGVVHSFCHNMNCNF

OR5T2

16

Q8NGG2
VLHNPHQTGCGHRFC

TRAF5

51

O00463
MHFHCTQCRHQFCSG

RNF31

886

Q96EP0
RSSGHHCELQCGHAF

RNF17

41

Q9BXT8
NRTCHCNGNFSGHNC

TYRP1

96

P17643
RHDHHCFFTGNCIGS

ZDHHC22

106

Q8N966
CHQHGLFEHQKTHNG

ZNF749

206

O43361
RIHTGENHHECNQCG

ZNF558

256

Q96NG5
RVCHHSCHNTVGSFL

VWCE

231

Q96DN2
HRQSHQTGHFGCQAC

ZNF646

1221

O15015
EQQVASLSGQCHHHG

SUN1

366

O94901
GNRTQSAHCHCGDHV

TOGARAM1

616

Q9Y4F4
VGHDHGCHQQPFCNA

UPK3B

186

Q9BT76