Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

KCNQ5 SCN2A SCN10A

8.35e-05171023GO:0099508
GeneOntologyBiologicalProcessbiphenyl catabolic process

UGT2B15 UGT2B17 UGT2B28

6.27e-0681013GO:0070980
GeneOntologyBiologicalProcessbiphenyl metabolic process

UGT2B15 UGT2B17 UGT2B28

1.33e-05101013GO:0018879
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT2B15 UGT2B17 UGT2B28

2.43e-05121013GO:0052697
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

PDCD6 SYNE1 PANX1 SORT1 ELOVL4 NBAS SEC22C MSMO1 TMEM208 NECAB3 UGT2B15 CLN6 UGT2B17 UGT2B28 RNF139 ATP2A3 GRAMD1C HERPUD1 MAN1B1 DGAT1

4.66e-06132710120GO:0042175
GeneOntologyCellularComponentendoplasmic reticulum membrane

PDCD6 PANX1 SORT1 ELOVL4 NBAS SEC22C MSMO1 TMEM208 NECAB3 UGT2B15 CLN6 UGT2B17 UGT2B28 RNF139 ATP2A3 GRAMD1C HERPUD1 MAN1B1 DGAT1

1.20e-05129310119GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

PDCD6 PANX1 SORT1 ELOVL4 NBAS SEC22C MSMO1 TMEM208 NECAB3 UGT2B15 CLN6 UGT2B17 UGT2B28 RNF139 ATP2A3 GRAMD1C HERPUD1 MAN1B1 DGAT1

1.28e-05129910119GO:0098827
GeneOntologyCellularComponentnuclear outer membrane

SYNE1 UGT2B15 UGT2B17 UGT2B28

4.10e-05401014GO:0005640
GeneOntologyCellularComponentendosome

IL12B SLC66A2 LZTR1 PDCD6 EIPR1 ACE SORT1 USP6 PLA2G4B MKLN1 LRP2 CLN6 PRKCD SNX31 GPNMB DNM2

1.45e-04116710116GO:0005768
GeneOntologyCellularComponentsynaptic membrane

GABRB2 SYNE1 OPRK1 KCNQ5 PTPRO SCN2A SCN10A MKLN1 ENO2 DNM2

5.20e-0458310110GO:0097060
DomainLIM-bd/SEUSS

LDB2 LDB1

2.95e-0521022IPR029005
DomainABM

NECAB2 NECAB3

8.83e-0531022PF03992
DomainABM_dom

NECAB2 NECAB3

8.83e-0531022IPR007138
DomainABM

NECAB2 NECAB3

8.83e-0531022PS51725
DomainUDPGT

UGT2B15 UGT2B17 UGT2B28

1.96e-04211023PF00201
DomainUDPGT

UGT2B15 UGT2B17 UGT2B28

1.96e-04211023PS00375
DomainUDP_glucos_trans

UGT2B15 UGT2B17 UGT2B28

1.96e-04211023IPR002213
DomainEF-hand_5

NECAB2 PDCD6 NECAB3

3.33e-04251023PF13202
PathwayREACTOME_PARACETAMOL_ADME

ACY1 UGT2B15 UGT2B17 UGT2B28

5.28e-0539754MM15695
PathwayKEGG_FC_GAMMA_R_MEDIATED_PHAGOCYTOSIS

ARPC1A CRK PLA2G4B PRKCD DNM2

1.56e-0496755M16121
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

SI UGT2B15 UGT2B17 UGT2B28

1.65e-0452754M14171
PathwayREACTOME_PREDNISONE_ADME

UGT2B15 UGT2B17 UGT2B28

2.37e-0423753MM16639
PathwayREACTOME_GLUCURONIDATION

UGT2B15 UGT2B17 UGT2B28

2.70e-0424753MM14599
PathwayREACTOME_GLUCURONIDATION

UGT2B15 UGT2B17 UGT2B28

3.06e-0425753M17787
PathwayWP_GLUCURONIDATION

UGT2B15 UGT2B17 UGT2B28

3.06e-0425753MM15820
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT2B15 UGT2B17 UGT2B28

3.06e-0425753M605
PathwayWP_GLUCURONIDATION

UGT2B15 UGT2B17 UGT2B28

3.44e-0426753M39404
PathwayKEGG_RETINOL_METABOLISM

UGT2B15 UGT2B17 UGT2B28 DGAT1

3.69e-0464754M9488
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT2B15 UGT2B17 UGT2B28

4.31e-0428753M19580
Pubmed

Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism.

UGT2B15 UGT2B17 UGT2B28

2.60e-083104319572376
Pubmed

Genetic variations in UGT2B28, UGT2B17, UGT2B15 genes and the risk of prostate cancer: A case-control study.

UGT2B15 UGT2B17 UGT2B28

2.60e-083104328882566
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

GABRB2 PDCD6 ITLN1 ARPC1A NAGLU ACY1 SLC44A4 ACE CRK MEGF8 PTPRO SCN10A LRP2 PRKCD DNM2

3.67e-0710161041519056867
Pubmed

Non-canonical Opioid Signaling Inhibits Itch Transmission in the Spinal Cord of Mice.

OPRK1 SCN10A PRKCD

9.01e-077104329669290
Pubmed

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.

UGT2B15 UGT2B17 UGT2B28

9.01e-077104326074487
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT2B15 UGT2B17 UGT2B28

1.44e-068104332093886
Pubmed

Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells.

UGT2B15 UGT2B17

8.86e-062104232660355
Pubmed

Sortilin/Omentin-1 ratio in peripheral artery disease: A cross-sectional study on 295 unselected elderly patients.

ITLN1 SORT1

8.86e-062104235500800
Pubmed

The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.

UGT2B15 UGT2B17

8.86e-06210421909870
Pubmed

Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications.

UGT2B15 UGT2B17

8.86e-062104224121496
Pubmed

Extensive metabolic consequences of human glycosyltransferase gene knockouts in prostate cancer.

UGT2B17 UGT2B28

8.86e-062104236347965
Pubmed

Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.

UGT2B15 UGT2B17

8.86e-062104224267955
Pubmed

Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.

UGT2B15 UGT2B17

8.86e-062104222170718
Pubmed

Spliced isoforms of LIM-domain-binding protein (CLIM/NLI/Ldb) lacking the LIM-interaction domain.

LDB2 LDB1

8.86e-062104216815859
Pubmed

PKCδ regulates IL-12p40/p70 production by macrophages and dendritic cells, driving a type 1 healer phenotype in cutaneous leishmaniasis.

IL12B PRKCD

8.86e-062104221287553
Pubmed

Localization of UDP glucuronosyltransferase gene(s) on mouse chromosome 5.

UGT2B15 UGT2B17

8.86e-06210423105095
Pubmed

UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells.

UGT2B15 UGT2B17

8.86e-062104217848572
Pubmed

Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.

UGT2B15 UGT2B17

8.86e-062104227496708
Pubmed

Cloning and chromosomal localization of two novel human genes encoding LIM-domain binding factors CLIM1 and CLIM2/LDB1/NLI.

LDB2 LDB1

8.86e-06210429799849
Pubmed

The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.

UGT2B15 UGT2B17

8.86e-062104217698910
Pubmed

Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation.

UGT2B15 UGT2B17

8.86e-06210423117546
Pubmed

Isolation and chromosomal assignment of human genes encoding cofactor of LIM homeodomain proteins, CLIM1 and CLIM2.

LDB2 LDB1

8.86e-062104210083735
Pubmed

Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation.

UGT2B15 UGT2B17

8.86e-062104228228532
Pubmed

Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium.

UGT2B15 UGT2B17

8.86e-062104215666817
Pubmed

Fucosyltransferase 2 (FUT2) non-secretor status is associated with Crohn's disease.

IL12B ARPC1A MMD2

1.71e-0517104320570966
Pubmed

Comprehensive analysis of low-abundance proteins in human urinary exosomes using peptide ligand library technology, peptide OFFGEL fractionation and nanoHPLC-chip-MS/MS.

NAGLU ACY1 ACE

1.71e-0517104321082674
Pubmed

Epigenetic regulation of steroid inactivating UDP-glucuronosyltransferases by microRNAs in prostate cancer.

UGT2B15 UGT2B17

2.65e-053104226385605
Pubmed

Cofactors of LIM Domains Associate with Estrogen Receptor α to Regulate the Expression of Noncoding RNA H19 and Corneal Epithelial Progenitor Cell Function.

LDB2 LDB1

2.65e-053104227129775
Pubmed

Interactions of the LIM-domain-binding factor Ldb1 with LIM homeodomain proteins.

LDB2 LDB1

2.65e-05310428918878
Pubmed

Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines.

UGT2B15 UGT2B17

2.65e-053104226163549
Pubmed

Forkhead box protein A1 regulates UDP-glucuronosyltransferase 2B15 gene transcription in LNCaP prostate cancer cells.

UGT2B15 UGT2B17

2.65e-053104220736324
Pubmed

NECABs: a family of neuronal Ca(2+)-binding proteins with an unusual domain structure and a restricted expression pattern.

NECAB2 NECAB3

2.65e-053104212044471
Pubmed

Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells.

UGT2B15 UGT2B17

2.65e-053104217988216
Pubmed

Expression of the calcium binding proteins Necab-1,-2 and -3 in the adult mouse hippocampus and dentate gyrus.

NECAB2 NECAB3

2.65e-053104223850650
Pubmed

Tissue distribution and relative gene expression of UDP-glucuronosyltransferases (2B7, 2B15, 2B17) in the human fetus.

UGT2B15 UGT2B17

2.65e-053104223223495
Pubmed

Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.

UGT2B15 UGT2B17

2.65e-053104218302198
Pubmed

The Ldb1 and Ldb2 transcriptional cofactors interact with the Ste20-like kinase SLK and regulate cell migration.

LDB2 LDB1

2.65e-053104219675209
Pubmed

The nuclear receptor Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression in mice.

UGT2B15 UGT2B17

2.65e-053104230689982
Pubmed

Lack of association of the renin-angiotensin system genes polymorphisms and left ventricular hypertrophy in hypertension.

ATR ACE

5.29e-054104211688760
Pubmed

Calcitrol (1alpha,25-dihydroxyvitamin D3) inhibits androgen glucuronidation in prostate cancer cells.

UGT2B15 UGT2B17

5.29e-054104218281521
Pubmed

Impacts of the Glucuronidase Genotypes UGT1A4, UGT2B7, UGT2B15 and UGT2B17 on Tamoxifen Metabolism in Breast Cancer Patients.

UGT2B15 UGT2B17

5.29e-054104226176234
Pubmed

Activation of PKC-delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy.

SIRPG PRKCD

5.29e-054104219881493
Pubmed

Defining the molecular basis of interaction between R3 receptor-type protein tyrosine phosphatases and VE-cadherin.

PTPRB PTPRO

8.80e-055104228926625
Pubmed

Involvement of TRPV1 and TDAG8 in Pruriception Associated with Noxious Acidosis.

GPR65 SCN10A

8.80e-055104227566399
Pubmed

Isl1 and Ldb co-regulators of transcription are essential early determinants of mouse limb development.

LDB2 LDB1

8.80e-055104222411555
Pubmed

Mouse deformed epidermal autoregulatory factor 1 recruits a LIM domain factor, LMO-4, and CLIM coregulators.

LDB2 LDB1

8.80e-05510429860983
Pubmed

p73beta is regulated by protein kinase Cdelta catalytic fragment generated in the apoptotic response to DNA damage.

CRK PRKCD

8.80e-055104212097319
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

NECAB2 CRK USP6 LDB1 MEGF8 MSMO1 LRP2 HERPUD1 TGS1

9.05e-05608104916713569
Pubmed

Inhibition of secretion of interleukin (IL)-12/IL-23 family cytokines by 4-trifluoromethyl-celecoxib is coupled to degradation via the endoplasmic reticulum stress protein HERP.

IL12B HERPUD1

1.32e-046104220054003
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN2A SCN10A

1.32e-046104223652591
Pubmed

The R3 receptor-like protein tyrosine phosphatase subfamily inhibits insulin signalling by dephosphorylating the insulin receptor at specific sites.

PTPRB PTPRO

1.32e-046104226063811
Pubmed

A family of LIM domain-associated cofactors confer transcriptional synergism between LIM and Otx homeodomain proteins.

LDB2 LDB1

1.32e-04610429192866
Pubmed

Leishmania donovani-induced expression of signal regulatory protein alpha on Kupffer cells enhances hepatic invariant NKT-cell activation.

IL12B SIRPG

1.32e-046104219877019
Pubmed

Steroidogenic enzymes and stem cell markers are upregulated during androgen deprivation in prostate cancer.

UGT2B15 UGT2B17

1.32e-046104221365123
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

UBR1 MTMR12 ATR NRDC RHOBTB3 INTS3 AACS MAN1B1 DNM2

1.49e-04650104938777146
Pubmed

Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice.

ACE GDPD4

1.84e-047104231455729
Pubmed

Genetic variation of genes involved in dihydrotestosterone metabolism and the risk of prostate cancer.

UGT2B17 UGT2B28

1.84e-047104220056642
Pubmed

RACK1, an insulin-like growth factor I (IGF-I) receptor-interacting protein, modulates IGF-I-dependent integrin signaling and promotes cell spreading and contact with extracellular matrix.

CRK PRKCD

1.84e-047104211884618
Pubmed

RPA70 depletion induces hSSB1/2-INTS3 complex to initiate ATR signaling.

ATR INTS3

1.84e-047104225916848
Pubmed

Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice.

PANX1 MMP19

1.84e-047104226163370
Pubmed

Expression of protein tyrosine phosphatase genes in the developing brain of mouse and rat.

PTPRB PTPRO

1.84e-04710427804149
Pubmed

Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.

UGT2B15 UGT2B17

2.45e-048104222579593
Pubmed

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

UGT2B15 UGT2B17

2.45e-048104218719240
Pubmed

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

UGT2B15 UGT2B17

2.45e-048104220142249
Pubmed

The expression and stage-specific localization of protein kinase C isotypes during mouse preimplantation development.

LDB1 PRKCD

2.45e-048104210882525
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

ITLN1 PTPRB LRP2 SNX31

2.47e-04101104423382219
Pubmed

Gut-brain communication by distinct sensory neurons differently controls feeding and glucose metabolism.

GPR65 SCN10A

3.14e-049104234043943
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN2A SCN10A

3.14e-049104216382098
Pubmed

Characterization of lipid-linked oligosaccharide accumulation in mouse models of Batten disease.

NAGLU CLN6

3.14e-049104215647513
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN2A ENO2

3.14e-049104215746173
Pubmed

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine.

PDCD6 NAGLU SI HID1 ACY1 SLC44A4 ACE MEGF8 LRP2 ENO2 DNM2

3.65e-0410701041123533145
Pubmed

Genetic Identification of Vagal Sensory Neurons That Control Feeding.

GPR65 SCN10A

3.92e-0410104231730854
Pubmed

Exome sequencing identifies breast cancer susceptibility genes and defines the contribution of coding variants to breast cancer risk.

LZTR1 ATR

3.92e-0410104237592023
Pubmed

Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.

JMJD4 PLA2G4B KDM8

4.33e-0449104334368113
Pubmed

PAQR proteins: a novel membrane receptor family defined by an ancient 7-transmembrane pass motif.

PAQR8 MMD2

4.79e-0411104216044242
Pubmed

Lgr5(+ve) stem/progenitor cells contribute to nephron formation during kidney development.

ACE LRP2

4.79e-0411104222999937
Pubmed

Ubiquitination-dependent cofactor exchange on LIM homeodomain transcription factors.

LDB2 LDB1

4.79e-0411104211882901
Pubmed

Protein tyrosine phosphatase SHP-1 positively regulates TLR-induced IL-12p40 production in macrophages through inhibition of phosphatidylinositol 3-kinase.

IL12B SIRPG

4.79e-0411104220145200
Pubmed

The DNA sequence and analysis of human chromosome 6.

SYNE1 PAQR8 CRISP3 SLC44A4 FBXL4 ELOVL4 KCNQ5 PRDM13

5.73e-04622104814574404
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT2B15 UGT2B17

5.73e-0412104220308471
Pubmed

Genome-wide isolation of growth and obesity QTL using mouse speed congenic strains.

UBR1 SIRPG

5.73e-0412104216670015
Pubmed

Dynamic spatiotemporal expression of LIM genes and cofactors in the embryonic and postnatal cerebral cortex.

LDB2 LDB1

5.73e-0412104212619132
Pubmed

Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells.

LDB2 LDB1

5.73e-0412104217991461
Pubmed

RLIM inhibits functional activity of LIM homeodomain transcription factors via recruitment of the histone deacetylase complex.

LDB2 LDB1

5.73e-0412104210431247
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

PDCD6 DNAH2 INTS3 FER1L6 USP6 TMTC3 MEGF8 DNM2

6.75e-04638104831182584
Pubmed

GC-GAP, a Rho family GTPase-activating protein that interacts with signaling adapters Gab1 and Gab2.

GABRB2 CRK

6.76e-0413104212819203
Pubmed

A DNA damage response screen identifies RHINO, a 9-1-1 and TopBP1 interacting protein required for ATR signaling.

ATR INTS3

6.76e-0413104221659603
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN2A SCN10A

6.76e-0413104215123669
Pubmed

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.

ATR NAGLU ELOVL4 LRP2 CLN6

6.94e-04233104532290105
Pubmed

Apocrine glands are bystanders in hidradenitis suppurativa and their involvement is gender specific.

SYNE1 CRK CATSPERB

7.48e-0459104332031713
Pubmed

Functional Analysis of Mmd2 and Related PAQR Genes During Sex Determination in Mice.

PAQR8 MMD2

9.07e-0415104235306493
Pubmed

Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.

ACE CRK MSMO1 AACS TGS1

9.51e-04250104518660489
Pubmed

LDB1 Is Required for the Early Development of the Dorsal Telencephalon and the Thalamus.

LDB2 LDB1

1.03e-0316104230873428
Pubmed

Genome wide association (GWA) predictors of anti-TNFalpha therapeutic responsiveness in pediatric inflammatory bowel disease.

IL12B ITLN1

1.03e-0316104220014019
Pubmed

Kv7/KCNQ potassium channels in cortical hyperexcitability and juvenile seizure-related death in Ank2-mutant mice.

GABRB2 SCN2A

1.31e-0318104237321992
Pubmed

Hypoxia-Regulated lncRNA USP2-AS1 Drives Head and Neck Squamous Cell Carcinoma Progression.

ATR ENO2

1.46e-0319104236359803
Pubmed

Ontogeny and Trophic Factor Sensitivity of Gastrointestinal Projecting Vagal Sensory Cell Types.

GPR65 SCN10A

1.46e-0319104236973009
Pubmed

LIM-homeodomain gene Lhx2 regulates the formation of the cortical hem.

LDB2 LDB1

1.46e-0319104211165475
Pubmed

gp 120s derived from four syncytium-inducing HIV-1 strains induce different patterns of CD4 association with lymphocyte surface molecules.

PTPRB PTPRO

1.62e-032010429263011
Pubmed

Pooled-matrix protein interaction screens using Barcode Fusion Genetics.

NECAB2 LNX2 CRK USP6 SNX31 DNM2

1.66e-03419104627107012
Cytoband6q14

ELOVL4 KCNQ5

1.04e-04710326q14
Cytoband4q13

UGT2B15 UGT2B17

5.14e-041510324q13
GeneFamilyN-terminal EF-hand calcium binding proteins|EF-hand domain containing

NECAB2 NECAB3

4.05e-053672663
GeneFamilyUDP glucuronosyltransferases

UGT2B15 UGT2B17 UGT2B28

2.23e-0432673363
GeneFamilySodium voltage-gated channel alpha subunits

SCN2A SCN10A

4.79e-0496721203
GeneFamilyProgestin and adipoQ receptor family

PAQR8 MMD2

7.28e-0411672930
GeneFamilyAAA ATPases|Peroxins

PEX7 PEX12

1.57e-0316672957
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRB PTPRO

2.71e-0321672813
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-MAIT-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 SIRPG ELOVL4 IL17RE PRDM13 NKG7

2.59e-061661046bb93db4613c067c56614ab1ca39e73ee46484387
ToppCellBAL-Mild-Lymphocyte-T/NK-CD8+_T-MAIT|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 SIRPG ELOVL4 IL17RE PRDM13 NKG7

2.59e-061661046c1f17a028bb27b8f202bcfffa7de7373b1cdd990
ToppCellCOVID-19-Heart-T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

SI FER1L6 KCNQ5 UGT2B15 NKG7 MMD2

3.08e-061711046b2e753e811a7639956994609f73efcdb62d04f82
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TEX14 MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

3.88e-061781046f815bc76f98aaea2d9058173b02b6f36e45283ce
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_B-Plasma_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TEX14 MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

3.88e-061781046a0334764e865fea652c54b94bbc3b173f7cbc9fc
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MEI1 KCNQ5 CHST15 UGT2B17 ATP2A3 HERPUD1

4.27e-0618110466cdee2f56bc633b387b4dbbd78c624edbd712c24
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_B-Plasma_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MEI1 KCNQ5 CHST15 UGT2B17 ATP2A3 HERPUD1

4.27e-061811046b75b8b025257bccfe661fd0f92ab284b2a9c12ee
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HID1 ACE LDB2 STK32A PTPRB ATP2A3

4.99e-061861046b80aaeebc03a318052076d2f02c123f5ddc5e73a
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HID1 ACE LDB2 STK32A PTPRB ATP2A3

4.99e-0618610468a8ed1502542d4895cba3fd5d534256206578716
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE LDB2 ELOVL4 STK32A PTPRB ATP2A3

5.15e-0618710467170694a1b86fe8d84d96c880ffe57af09bdc026
ToppCelldroplet-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HID1 ACE LDB2 STK32A PTPRB ATP2A3

5.47e-0618910462e43428f1ef9683c6f8c9897d46aa7d34bf9047f
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE LDB2 ELOVL4 STK32A PTPRB ATP2A3

5.81e-0619110466e6b2cb390cc5cd0356924a2c36fbe5b5bd5966c
ToppCellfacs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE LDB2 ELOVL4 STK32A PTPRB ATP2A3

5.81e-061911046482db995930346be69072ace2fd78fd453e97fb5
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPR65 SIRPG ELOVL4 IL17RE PRDM13 NKG7

6.54e-061951046c7b54b210cc2c8ddaefebfba74381adb2ca698b8
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GPR65 SIRPG ELOVL4 IL17RE PRDM13 NKG7

6.54e-061951046e173a713d273b135db4f71bdcaada3b0e55d74f1
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

GPR65 SIRPG ELOVL4 IL17RE PRDM13 NKG7

6.54e-06195104659164d115a0928cc9b79c7661c7190ad695f9d80
ToppCellPBMC-Control-Lymphocyte-T/NK-CD8+_T-MAIT-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPR65 SIRPG ELOVL4 IL17RE PRDM13 NKG7

6.54e-061951046a8fd42ff6c2bd80d0e3f20fe3bbf7d113b399df1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 RHOBTB3 PANX1 SNED1 NAV2 MMP19

7.14e-061981046a860246bcea847249a78fd2e86ed8e04371060db
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNE1 LDB2 STK32A SNED1 VCAN NAV2

7.56e-062001046a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

STK32A IL17RE PLA2G4B NAV2 CATSPERB MMP19

7.56e-062001046eac33be484dc443794e66e473f03e98406c2983e
ToppCellTracheal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNE1 LDB2 SNED1 VCAN NAV2 GPNMB

7.56e-062001046b4ccffdd79526c85e5273d27b668dbddcddba1ee
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SYNE1 LDB2 SNED1 VCAN NAV2 GPNMB

7.56e-0620010460c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2-Excitatory_Neuron.Slc17a7.Calb2-Vgll3_(Dentate_hilum?)|Hippocampus / BrainAtlas - Mouse McCarroll V32

GDPD4 ADGRG7 SCN10A LRP2

1.19e-05601044aa75fef294803ec6396c7d2c1f51d52bc4a5b43f
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2-Excitatory_Neuron.Slc17a7.Calb2-Vgll3_(Dentate_hilum?)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

GDPD4 ADGRG7 SCN10A LRP2

1.19e-05601044069fbabfd0e48e5809ff01a026439fd0bd017779
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE PTPRO VCAN PRKCD GPNMB

3.38e-051571045d8e283414a770f05d71f0455d0822e9a9660b115
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE PTPRO VCAN PRKCD GPNMB

3.38e-051571045165e98bf944572cafbc06ef43c9eab7bd6bea1c2
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma|TCGA-Bladder / Sample_Type by Project: Shred V9

MKRN2OS HID1 ACY1 SLC44A4 STK32A

3.48e-051581045dc559503bab3ec1b9ea54ef2e896d1be33e5344c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 LDB2 SNED1 PTPRB KCNQ5

3.59e-051591045d3f81ba22160568ccaa6d2b04ebfd30630f9a6db
ToppCellCOVID-19-kidney-Plasma|COVID-19 / Disease (COVID-19 only), tissue and cell type

MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

3.70e-051601045f8d9e459976e711e9ad39ea2b6173140c0589d6e
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NECAB2 MEI1 OPRK1 KCNQ5 CHST15

4.67e-051681045b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NECAB2 MEI1 OPRK1 KCNQ5 CHST15

4.67e-051681045b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 LDB2 SNED1 PTPRB IL17RE

4.80e-051691045987ff79ad563825dd9877ea8ccb536758f8c6700
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

4.94e-051701045a965e3ee6818790a4a6916824fde64333d9b11b7
ToppCellCOVID-19-kidney-Plasma|kidney / Disease (COVID-19 only), tissue and cell type

MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

5.08e-051711045a59a054b8e119215f24dc5c80ad5a8094b3500f9
ToppCelldroplet-Kidney-nan-18m-Lymphocytic-plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PANX1 HID1 KCNQ5 HERPUD1 MAN1B1

5.51e-051741045c92eec5a14ca5269673582dd115ead8516e64c3e
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LNX2 ITLN1 SLC44A4 SNX31 CATSPERB

5.51e-0517410453f0a5ce074675d57d479fa069385a1b3071e884e
ToppCelldroplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l2|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PANX1 SORT1 IL17RE EXOC6B MMP19

5.82e-0517610451510cdfcfb46ce1196a1220c07fb5f3986c81b78
ToppCellControl-B_cells|Control / group, cell type (main and fine annotations)

MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

5.82e-0517610459125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCellEndothelial-Endothelial-C|Endothelial / shred on cell class and cell subclass (v4)

PEX12 ACE LDB2 STK32A PTPRB

5.98e-051771045b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCellMild-Lymphoid-T-innate_T|Mild / Condition, Lineage, Cell class and cell subclass

SYNE1 SIRPG IL17RE PRDM13 NKG7

6.30e-051791045abc0fbe101a464a2c85755a974a3d5c2b968fe46
ToppCellEntopeduncular-Macroglia|Entopeduncular / BrainAtlas - Mouse McCarroll V32

RHOBTB3 ARPC1A ACY1 MSMO1 MMD2

6.30e-051791045f61974710a60aa0618fdb30d864fb9bc7c05ef21
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

KCNQ5 VCAN NAV2 CATSPERB MMP19

6.64e-0518110452b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCellCOVID-19-B_cells-Plasma_cells|COVID-19 / group, cell type (main and fine annotations)

MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

7.00e-051831045130c109f63a5e3c8f83cb96e32f4addf513b6415
ToppCellCOVID-19-B_cells|COVID-19 / group, cell type (main and fine annotations)

MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

7.00e-0518310452c016bb59f131a0e821853b085289a3583f0a729
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_int|lung / Disease (COVID-19 only), tissue and cell type

MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

7.18e-051841045480595a0e2e6aa2a77b7daa36490ae3af3d8dfee
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|368C / Donor, Lineage, Cell class and subclass (all cells)

MEI1 HPS4 PDE5A NKG7 FAM199X

7.18e-051841045d48807f9da48bdd015a54c606d2e2a311f181396
ToppCellP28-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ACE LDB2 ELOVL4 STK32A PTPRB

7.18e-0518410458ed22b1af04a711203293e7a8b3df6fb9222fad5
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GABRB2 ACE STK32A PTPRB SCN2A

7.37e-05185104587151ab95530e70d61328b336518df58db584acb
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|lung / Disease (COVID-19 only), tissue and cell type

MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

7.56e-05186104566676d9395172de5707e204826a1c9f73b448cca
ToppCell21-Trachea-Epithelial-Goblet-like_secretory|Trachea / Age, Tissue, Lineage and Cell class

ITLN1 CRISP3 HID1 ACE UGT2B15

7.56e-051861045f8cddad28896f0edf10a8645fa49a011b22b120d
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE LDB2 ELOVL4 STK32A PTPRB

7.56e-0518610459c7924875f70420720149287c500b4dfa8d24673
ToppCell(2)_Fibroblasts-(20)_Fibro-1|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis

ACE LDB2 SNED1 GPNMB MMP19

7.56e-051861045e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HID1 LDB2 ELOVL4 STK32A PTPRB

7.56e-0518610455302399825f213d105ac70b91366a4513b732838
ToppCellSMG-Goblet|World / shred by cell class for bronchial biopsy

ITLN1 NAGLU CRISP3 ATP2A3 HERPUD1

7.75e-0518710455178118bdec91495253c88f58fd908cf831de7ef
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE LDB2 ELOVL4 STK32A PTPRB

7.75e-05187104512129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM202 VCAN LRP2 GPNMB MMP19

7.75e-0518710454e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM202 VCAN LRP2 GPNMB MMP19

7.75e-051871045d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM202 VCAN LRP2 GPNMB MMP19

7.75e-051871045827eae63fabf6892a82ce7779b5f395958d3d628
ToppCelldroplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ACE LDB2 ELOVL4 STK32A PTPRB

7.75e-05187104583930ef55191eff9006113feaeabb3c2fa21fd05
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LNX2 ACE PTPRB LDB1 ATP2A3

7.75e-0518710453699d5e71d779da922920aa3160895db187bf81b
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LNX2 ACE PTPRB LDB1 ATP2A3

7.75e-051871045033ba52c0c2f9978784947098fa697368ae44834
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_int|COVID-19 / Disease (COVID-19 only), tissue and cell type

MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

7.95e-051881045599195338070ac6b79bd114609d9e10cac4f1df4
ToppCelldroplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE LDB2 ELOVL4 STK32A PTPRB

7.95e-051881045405efea75233ecf70f7d19b630230798d817b7f2
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

7.95e-051881045567b08514d9d84cbb40f9b7a679eec304f023428
ToppCellRA-14._Fibroblast_III|RA / Chamber and Cluster_Paper

SNED1 VCAN NAV2 CATSPERB MMP19

8.15e-05189104546e9a58aacd79db5a02898a8c7244e1884adcfd1
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SYNE1 CRISP3 SORT1 NAV2 NKG7

8.15e-0518910453b35022c0619df6db234613aa53a076899ca9562
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SYNE1 CRISP3 SORT1 NAV2 NKG7

8.15e-051891045358ff514f1c8aa46067208ddf1b68396d789c130
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC-AEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HID1 ACE LDB2 STK32A PTPRB

8.15e-0518910459da012fdfa9a8d488cab710a463a1d70e89f990c
ToppCellmild-Myeloid-Immature_Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SYNE1 CRISP3 SORT1 NAV2 NKG7

8.15e-05189104594dd5d4d815449feff7ce157fe7f8234f7c81422
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 RHOBTB3 PANX1 NAV2 MMP19

8.35e-0519010451121eb607a984c59fbffe7220837fc178745aa55
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

HID1 LDB2 SNED1 PTPRB CATSPERB

8.35e-0519010456e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 RHOBTB3 PANX1 NAV2 MMP19

8.35e-051901045048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellcontrol-Myeloid-Immature_Neutrophils_1|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SYNE1 CRISP3 SORT1 NAV2 NKG7

8.35e-05190104538e83337c70c8734b63f8589ba59e0f98603f94c
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HID1 ACE LDB2 STK32A PTPRB

8.56e-0519110453307dbccadb09c62b0e1c0235ec89bb294d748c3
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK32A TMTC3 MSMO1 PDE5A ATP2A3

8.56e-051911045f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCellCOVID-19_Mild-MAIT|COVID-19_Mild / Disease condition and Cell class

GPR65 ELOVL4 IL17RE NKG7 HERPUD1

8.56e-051911045e834d7a6aa7bb4f194b203d351e53bf5d95175d6
ToppCell10x5'-bone_marrow-Lymphocytic_Invariant-Inducer-like-MAIT|bone_marrow / Manually curated celltypes from each tissue

GPR65 SIRPG ELOVL4 IL17RE PRDM13

8.56e-0519110457a28905ad504979497836e87df81d529e675ce78
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK32A TMTC3 MSMO1 PDE5A ATP2A3

8.77e-0519210455b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellcontrol-Myeloid-Immature_Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SYNE1 CRISP3 SORT1 NAV2 NKG7

8.77e-0519210459f12b79d661ef0f57c2c924e8ecc24a46ea996d2
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HID1 PTPRO AACS ATP2A3 HERPUD1

8.99e-0519310455a92697430f16c49e19a5f727d289d7bd1ece31c
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HID1 PTPRO AACS ATP2A3 HERPUD1

8.99e-05193104564bcdbb422f8da6fc3275e82f6aaf562f546a180
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHOBTB3 SORT1 SCN2A VWA5B1 TGS1

9.21e-05194104504bfc555743f7d8821439d05ae442d15e9886c59
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SYNE1 SIRPG ELOVL4 NKG7 HERPUD1

9.21e-051941045b0a7f5ca0c6f4f5764a8b35b5de80d82b828c66c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RHOBTB3 SORT1 SCN2A VWA5B1 TGS1

9.21e-05194104569bff17df4a760ccf081cf52ff04af02c14f448d
ToppCell3'-Adult-LargeIntestine-Hematopoietic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPR65 MEI1 SIRPG NKG7 HERPUD1

9.44e-05195104538ed4f48d450119cd50d6b85bd2d966a39d02c6b
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITLN1 HID1 FER1L6 IL17RE UGT2B15

9.44e-051951045e1fb987f13482d1fce0428413244be3621136424
ToppCell3'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITLN1 HID1 FER1L6 IL17RE UGT2B15

9.44e-051951045482a2e7db72f0da285bb658943dd668777519734
ToppCellfacs-Lung-nan-3m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE LDB2 SNED1 PTPRB ATP2A3

9.44e-0519510457f9b7f15006610ad591063d90e90367bd6083c7f
ToppCellsevere-Myeloid-Immature_Neutrophils_1|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SYNE1 CRISP3 SORT1 NAV2 NKG7

9.44e-051951045becad890a420267ca41e98e61a8da343b51e1945
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITLN1 HID1 SLC44A4 FER1L6 ATP2A3

9.67e-051961045847b3377f463bfded046eec63cc1b547f3dc33c1
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-B|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MEI1 KCNQ5 CHST15 ATP2A3 HERPUD1

9.67e-051961045fc67d8aad1ec4d7f98ffe44fb103e230b9b42c35
ToppCellControl-Lymphocyte-T_NK-NK|Control / Disease, Lineage and Cell Type

GPR65 SYNE1 RHOBTB3 LDB2 NKG7

9.67e-05196104565838fddc920cdcecefe823f3ce1c95a7e50e82b
ToppCellCOVID-19_Severe-Neu_2|World / 5 Neutrophil clusters in COVID-19 patients

SYNE1 CRISP3 SORT1 NAV2 NKG7

9.67e-05196104516359a56297f0558fc93fa52563cce0c53def167
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HID1 TEX14 MEI1 CHST15 HERPUD1

9.67e-051961045fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCell(2)_NK/T-(220)_CD8+_Cytotoxic_T_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

GPR65 ELOVL4 IL17RE NKG7 HERPUD1

9.67e-051961045d123361c32bcd2329200f0316bc5b54bb494e92d
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHST15 VCAN GPNMB MMP19 ENO2

9.90e-05197104524bcd56df43796af2833c7ce37719c76dd299c19
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHST15 VCAN GPNMB MMP19 ENO2

9.90e-051971045ea7dd7f90be34d8e5936c9c8d35e0918ae64433b
ToppCellsevere-Myeloid-Immature_Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

SYNE1 CRISP3 SORT1 NAV2 NKG7

9.90e-0519710459599319dd1f80c81356a8624131566cc76d77d7e
ToppCell5'-Adult-LargeIntestine-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITLN1 HID1 SLC44A4 FER1L6 ATP2A3

9.90e-051971045d624f3a105b19f19a0dd253ce8de3ed13adc1f01
ToppCellCOVID-19_Severe-Neu_2|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients

SYNE1 CRISP3 SORT1 NAV2 NKG7

9.90e-051971045945f19475905cdedf232315eea1076ca0b753b67
Drugmethoxyresorufin

PDCD6 NAGLU HPS4 UGT2B15 UGT2B17 UGT2B28

7.04e-07691036CID000119220
Drugpentoxyresorufin

PDCD6 NAGLU HPS4 UGT2B15 UGT2B17 UGT2B28

2.78e-06871036CID000107683
DiseaseDNA repair protein RAD51 homolog 4 measurement

TEX14 UGT2B15 UGT2B17

5.93e-0611993EFO_0801531
Diseasecholic acid glucuronide measurement

UGT2B15 UGT2B17

3.34e-053992EFO_0800574
DiseaseX-25937 measurement

UGT2B15 UGT2B17

6.66e-054992EFO_0800937
DiseaseSudden death

ACE SCN10A

1.11e-045992C0011071
DiseaseX-24574 measurement

UGT2B15 UGT2B17

2.31e-047992EFO_0800897
Diseasedeoxycholic acid glucuronide measurement

UGT2B15 UGT2B17

3.08e-048992EFO_0800575
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN2A SCN10A

4.93e-0410992DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN2A SCN10A

4.93e-0410992DOID:0080422 (implicated_via_orthology)
Disease4-androsten-3alpha,17alpha-diol monosulfate (3) measurement

UGT2B15 UGT2B17

4.93e-0410992EFO_0022090
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

PANX1 ACE

6.01e-0411992DOID:0110861 (biomarker_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN2A SCN10A

7.20e-0412992DOID:0060170 (implicated_via_orthology)
Disease5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement

UGT2B15 UGT2B17

7.20e-0412992EFO_0800291
DiseaseIntellectual Disability

GABRB2 SYNE1 NAGLU ACY1 KCNQ5 LRP2 MAN1B1

7.85e-04447997C3714756
Diseasedevelopmental and epileptic encephalopathy (implicated_via_orthology)

KCNQ5 DNM2

8.48e-0413992DOID:0112202 (implicated_via_orthology)
Diseaseandrostenediol (3alpha, 17alpha) monosulfate (3) measurement

UGT2B15 UGT2B17

8.48e-0413992EFO_0800293
DiseaseX-19141 measurement

UGT2B15 UGT2B17

8.48e-0413992EFO_0800799
Diseasefertility measurement

NBAS NAV2

9.88e-0414992EFO_0006923
Diseasewet macular degeneration

SLC44A4 HERPUD1

9.88e-0414992EFO_0004683
DiseaseHypothermia, natural

IL12B PRKCD

9.88e-0414992C0020672
Disease5alpha-androstan-3alpha,17alpha-diol monosulfate measurement

UGT2B15 UGT2B17

9.88e-0414992EFO_0800283
DiseasePeroxisome biogenesis disorders

PEX7 PEX12

1.14e-0315992C1832200
Diseasethird ventricle volume measurement

LDB2 LDB1

1.14e-0315992EFO_0010335
DiseaseHETE measurement

FER1L6 NBAS SEC22C

1.20e-0362993EFO_0801166
Diseasemyocardial infarction (implicated_via_orthology)

ACE OPRK1 PDE5A

1.44e-0366993DOID:5844 (implicated_via_orthology)
Disease5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement

UGT2B15 UGT2B17

1.65e-0318992EFO_0800288
Diseasesensorineural hearing loss (implicated_via_orthology)

LNX2 SLC44A4

1.84e-0319992DOID:10003 (implicated_via_orthology)
Diseaseetiocholanolone glucuronide measurement

UGT2B15 UGT2B17

1.84e-0319992EFO_0800362
Diseaseandrosterone glucuronide measurement

UGT2B15 UGT2B17

2.04e-0320992EFO_0800317
DiseaseAlcoholic Intoxication, Chronic

GABRB2 NRDC ACE OPRK1 HERPUD1

2.13e-03268995C0001973
DiseaseX-24947 measurement

UGT2B15 UGT2B17

2.46e-0322992EFO_0800910
Diseasenephrosis (biomarker_via_orthology)

ACE LRP2

2.46e-0322992DOID:2527 (biomarker_via_orthology)
DiseaseLiver Failure, Acute

PANX1 GPNMB

2.93e-0324992C0162557
Diseaseglioblastoma (is_implicated_in)

LZTR1 PTPRB

2.93e-0324992DOID:3068 (is_implicated_in)
DiseaseCardiac Arrhythmia

ACE OPRK1

3.18e-0325992C0003811
Diseaseepiandrosterone sulfate measurement

UGT2B15 UGT2B17

3.18e-0325992EFO_0021120

Protein segments in the cluster

PeptideGeneStartEntry
ENWLCFYSNIFRWET

GRAMD1C

106

Q8IYS0
FWHDYDTTWFNMTQT

CATSPERB

216

Q9H7T0
DFRWTDGSTLQYENW

VCAN

3236

P13611
YWRSWYNSPTFEDDL

ACE

226

P12821
YHWSVESYSDFWAEF

AACS

51

Q86V21
ESYSDFWAEFWKFSG

AACS

56

Q86V21
YVYNWTAWSEDSDGE

GPNMB

131

Q14956
YACVYWNLSAKDWDT

ADGRG7

381

Q96K78
GDREFYRDWWNSESV

DGAT1

356

O75907
FDQDDWAAWSKFTAN

ENO2

296

P09104
LATVAAATWWFVYDA

ATP2A3

846

Q93084
SVCYFESENDWWVSK

ARPC1A

121

Q92747
NTSIWYNRSDVFEAW

NAGLU

526

P54802
MAGNFDSEERSSWYW

CRK

1

P46108
LDWETFEQYCAWQLF

INTS3

801

Q68E01
NRDWLDWTYSAATFS

HERPUD1

261

Q15011
NFIGNYASTFTWWDR

MSMO1

256

Q15800
YASTFTWWDRIFGTD

MSMO1

261

Q15800
TWWDRIFGTDSQYNA

MSMO1

266

Q15800
WFNWSPASGDFDFYE

PTPRB

1191

P23467
LYFLSDDDWETISAW

MMD2

56

Q8IY49
GWSTDEANTYFKEWT

ITLN1

16

Q8WWA0
DLFEYKFATGQWTEW

LZTR1

151

Q8N653
DNLWWDAFTTEFFED

LDB1

86

Q86U70
DNSTEFWDTDIKWFS

MTMR12

341

Q9C0I1
TFSVDWWSFGVLLYE

PRKCD

526

Q05655
STALNDTVEFYRWTW

ELOVL4

16

Q9GZR5
WTNTLNFDEYIASWK

MFI

236

Q8NCR3
ANKEFSTYADALWWG

KCNQ5

291

Q9NR82
STEAKSASWWNYFFL

HPS4

6

Q9NQG7
FQSWPEAYGSDFWKS

IL17RE

261

Q8NFR9
YVRALDLSFSVSFWW

KDM8

401

Q8N371
SDNLWWDAFATEFFE

LDB2

46

O43679
TFSENEYDASWSPSW

LNX2

571

Q8N448
STYWDWSDSEFEWQL

FAM199X

126

Q6PEV8
NFSEFTGVWKYITDW

PDCD6

81

O75340
WQWDELARTDFSSYP

MMP19

401

Q99542
EAWLDDHWDFTFSYF

PDE5A

31

O76074
FRSFDWNDGLFDVTW

PEX7

61

O00628
DLVLYNFSANTWESW

MEGF8

256

Q7Z7M0
WIETSSEYFNFDWVT

GDPD4

6

Q6W3E5
WVSFWINYDASAARV

GABRB2

261

P47870
FAITIFEDTIYWTDW

LRP2

3411

P98164
LFIQWDWSTYLADYG

EXOC6B

736

Q9Y2D4
DSLYWASEPSQFWDR

PLA2G4B

511

P0C869
SFSWRQAAFVDSYCW

PANX1

71

Q96RD7
YWFVLTAESLSWYKD

DNM2

541

P50570
QDRYYSSSWSEWASV

IL12B

311

P29460
SFYPLIDVNWWADSA

NBAS

386

A2RRP1
YAVDWSSADPWLFAS

EIPR1

351

Q53HC9
YQDWGWEILQSFSRF

MAN1B1

616

Q9UKM7
LELWFFWEESSYEEL

MEI1

801

Q5TIA1
YETTSQPYWWDSASA

PTPRO

291

Q16827
SSDQAWYDRFWLFFL

PAQR8

166

Q8TEZ7
NFAEWSASWAGYLIT

ATR

1486

Q13535
SSSWSQAIQSWFDEY

CRISP3

106

P54108
FTQTAVFRTYGTWWD

FBXL4

91

Q9UKA2
VYFSSDWLNEFWDAL

JMJD4

201

Q9H9V9
IFEDFAQSWYWILVA

SLC44A4

221

Q53GD3
SFDWLSQLRFYWEKD

DNAH2

1736

Q9P225
ELTVWYSNSLAQWFD

PRDM13

106

Q9H4Q3
FLETLWWEFTASYDT

SEC22C

86

Q9BRL7
QTFFSWSFYLGWVSA

NKG7

126

Q16617
WDIFDSDWYTSRNLI

RHOBTB3

76

O94955
SLQFPDDDYSWWDLF

OPRK1

211

P41145
NETDSFFISWDDFWD

RNF139

261

Q8WU17
SAENVIDWWSKYYAS

FER1L6

1206

Q2WGJ9
EWSSSDVMNYFAWER

REG3A

121

Q06141
WGFTESFLTSQWVSY

SORT1

586

Q99523
ETEYSFDDWDWQNGS

TEX14

691

Q8IWB6
WKDYTSRFSEFSSWI

SYNE1

1126

Q8NF91
WQKFLDDYSRFEDWL

SYNE1

8001

Q8NF91
WDGTQDLADFWAYSV

MKLN1

291

Q9UL63
DLADFWAYSVKENQW

MKLN1

296

Q9UL63
ATDDAFWDQFWADTA

HID1

26

Q8IV36
VDGSRVWFTDLWNYS

NAV2

2351

Q8IVL1
AFPDFFRTSTAEWWA

SI

1361

P14410
EYFDWVWDDLNKSSA

SPSB3

101

Q6PJ21
SFAVDWWSLGVTAYE

STK32A

201

Q8WU08
FFLQFLDWWYSSENQ

PEX12

256

O00623
TENKDGTYNWTSWFL

SIRPG

301

Q9P1W8
RFQYSEDSCWQWFVI

SNX31

346

Q8N9S9
LLDFNATWVFVATWY

SNED1

141

Q8TER0
TDAFTVFYSERSPWW

ACY1

181

Q03154
DLWFYFTLQNWVLDF

CLN6

46

Q9NWW5
TMWDNNAWTFFYDNS

CHST15

351

Q7LFX5
WEYTFKVNWSDLSVT

ZCCHC2

371

Q9C0B9
FGDLAIYFSQEEWEW

ZNF667

16

Q5HYK9
TDVWAVYFSQFWIDY

UHRF1BP1L

691

A0JNW5
QWDKYLEDFSTSGAW

MKRN2OS

126

H3BPM6
QFSDFKWELYNWRET

THAP9

191

Q9H5L6
EFTYLRDPWNWLDFS

SCN10A

181

Q9Y5Y9
WNWLDFTVITFAYVT

SCN2A

191

Q99250
ASWWDQQVDFYTAFL

UBR1

26

Q8IWV7
WFGTQYSIEDIENSW

NRDC

626

O43847
IDYTWNKDNWTFSPA

GPR65

71

Q8IYL9
TLVFFYSSASFWAWL

TMEM208

41

Q9BTX3
FWSYFSQLQELCWEY

UGT2B15

106

P54855
QFQYWEAQGWTFDAS

TGS1

251

Q96RS0
RWSDIQKDSFWLYFS

UGT2B28

96

Q9BY64
TFHRNWDWESEYTLF

TMTC3

421

Q6ZXV5
ESDLLWTYYLNWCSD

TMEM202

186

A6NGA9
WFTRELFSEWFFQNF

TIGD7

256

Q6NT04
HFWQWSSFSDYVQCV

SLC66A2

136

Q8N2U9
YDFEWSCWVRAISQE

USP6

471

P35125
WQWFYEETESSDDVE

ZHX1-C8orf76

6

Q96EF9
FWSYFSQLQELCWEY

UGT2B17

106

O75795
YFTEWELVAAKANSW

VWA5B1

1161

Q5TIE3
CISVDSWWADLNYFL

LEG1

121

Q6P5S2
FTFVIYEFWETEEAW

NECAB2

331

Q7Z6G3
ASFTLYEFWQDEASW

NECAB3

341

Q96P71