Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled photoreceptor activity

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

6.87e-0815554GO:0008020
GeneOntologyMolecularFunctionphotoreceptor activity

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

1.19e-0717554GO:0009881
GeneOntologyMolecularFunctionretinoic acid binding

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.00e-0628554GO:0001972
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.53e-0635554GO:0015020
GeneOntologyMolecularFunctionretinoid binding

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.16e-0648554GO:0005501
GeneOntologyMolecularFunctionisoprenoid binding

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.95e-0649554GO:0019840
GeneOntologyMolecularFunctionUDP-glycosyltransferase activity

UGT1A4 UGT1A3 UGT1A6 UGT1A5 POGLUT2

6.32e-05153555GO:0008194
GeneOntologyMolecularFunctionCTPase activity

ENTPD7 ENTPD4

1.11e-046552GO:0043273
GeneOntologyMolecularFunctionmonocarboxylic acid binding

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.15e-04107554GO:0033293
GeneOntologyMolecularFunctionUDP phosphatase activity

ENTPD7 ENTPD4

2.65e-049552GO:0045134
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT1A4 UGT1A3 UGT1A6 UGT1A5 POGLUT2

2.85e-04211555GO:0016758
GeneOntologyMolecularFunctionGDP phosphatase activity

ENTPD7 ENTPD4

4.83e-0412552GO:0004382
GeneOntologyMolecularFunctioncarboxylic acid binding

UGT1A4 UGT1A3 UGT1A6 UGT1A5 L1CAM

5.03e-04239555GO:0031406
GeneOntologyMolecularFunctionorganic acid binding

UGT1A4 UGT1A3 UGT1A6 UGT1A5 L1CAM

6.63e-04254555GO:0043177
GeneOntologyMolecularFunctionprotein heterodimerization activity

UGT1A4 UGT1A3 UGT1A6 UGT1A5 JAM3 CHUK

7.68e-04398556GO:0046982
GeneOntologyMolecularFunctionglycosyltransferase activity

UGT1A4 UGT1A3 UGT1A6 UGT1A5 POGLUT2

1.16e-03288555GO:0016757
GeneOntologyMolecularFunctionnucleoside diphosphate phosphatase activity

ENTPD7 ENTPD4

1.37e-0320552GO:0017110
GeneOntologyBiologicalProcesscellular glucuronidation

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.62e-0721554GO:0052695
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.47e-0726554GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.47e-0726554GO:0006063
GeneOntologyBiologicalProcessribonucleotide catabolic process

ENTPD7 GALT FKRP RPTOR NUDT8 ENTPD4

7.75e-06178556GO:0009261
GeneOntologyBiologicalProcessphototransduction

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

1.20e-0553554GO:0007602
GeneOntologyBiologicalProcessdetection of visible light

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

1.61e-0557554GO:0009584
GeneOntologyBiologicalProcessribonucleoside diphosphate catabolic process

ENTPD7 GALT FKRP RPTOR ENTPD4

1.76e-05121555GO:0009191
GeneOntologyBiologicalProcessnucleotide catabolic process

ENTPD7 GALT FKRP RPTOR NUDT8 ENTPD4

1.88e-05208556GO:0009166
GeneOntologyBiologicalProcessnucleoside diphosphate catabolic process

ENTPD7 GALT FKRP RPTOR ENTPD4

1.98e-05124555GO:0009134
GeneOntologyBiologicalProcessUDP catabolic process

ENTPD7 ENTPD4

2.09e-053552GO:0006256
GeneOntologyBiologicalProcesspyrimidine nucleoside diphosphate catabolic process

ENTPD7 ENTPD4

2.09e-053552GO:0009140
GeneOntologyBiologicalProcesspyrimidine ribonucleoside diphosphate catabolic process

ENTPD7 ENTPD4

2.09e-053552GO:0009195
GeneOntologyBiologicalProcessnucleoside phosphate catabolic process

ENTPD7 GALT FKRP RPTOR NUDT8 ENTPD4

2.33e-05216556GO:1901292
GeneOntologyBiologicalProcesscellular response to light stimulus

OPN1MW2 OPN1MW3 OPN1LW EIF2AK4 OPN1MW

2.49e-05130555GO:0071482
GeneOntologyBiologicalProcessvisual perception

OPN1MW2 OPN1MW3 SLC4A7 OPN1LW NXNL2 OPN1MW

3.31e-05230556GO:0007601
GeneOntologyBiologicalProcesspurine nucleotide metabolic process

ENTPD7 SLC4A7 GALT EHHADH FKRP RPTOR NUDT8 NDUFB5 ENTPD4

3.45e-05619559GO:0006163
GeneOntologyBiologicalProcesssensory perception of light stimulus

OPN1MW2 OPN1MW3 SLC4A7 OPN1LW NXNL2 OPN1MW

3.56e-05233556GO:0050953
GeneOntologyBiologicalProcessribonucleoside diphosphate metabolic process

ENTPD7 GALT FKRP RPTOR ENTPD4

3.93e-05143555GO:0009185
GeneOntologyBiologicalProcessnucleoside diphosphate metabolic process

ENTPD7 GALT FKRP RPTOR ENTPD4

4.78e-05149555GO:0009132
GeneOntologyBiologicalProcesspurine-containing compound metabolic process

ENTPD7 SLC4A7 GALT EHHADH FKRP RPTOR NUDT8 NDUFB5 ENTPD4

5.17e-05652559GO:0072521
GeneOntologyBiologicalProcessdetection of light stimulus

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

5.30e-0577554GO:0009583
GeneOntologyBiologicalProcesspurine ribonucleotide metabolic process

ENTPD7 GALT EHHADH FKRP RPTOR NUDT8 NDUFB5 ENTPD4

5.96e-05512558GO:0009150
GeneOntologyBiologicalProcessnucleotide metabolic process

ENTPD7 SLC4A7 GALT EHHADH FKRP RPTOR NUDT8 NDUFB5 ENTPD4

7.47e-05684559GO:0009117
GeneOntologyBiologicalProcessribonucleotide metabolic process

ENTPD7 GALT EHHADH FKRP RPTOR NUDT8 NDUFB5 ENTPD4

7.89e-05533558GO:0009259
GeneOntologyBiologicalProcessnucleoside phosphate metabolic process

ENTPD7 SLC4A7 GALT EHHADH FKRP RPTOR NUDT8 NDUFB5 ENTPD4

8.08e-05691559GO:0006753
GeneOntologyBiologicalProcessribose phosphate metabolic process

ENTPD7 GALT EHHADH FKRP RPTOR NUDT8 NDUFB5 ENTPD4

8.64e-05540558GO:0019693
GeneOntologyBiologicalProcesspurine ribonucleotide catabolic process

GALT FKRP RPTOR NUDT8 ENTPD4

8.69e-05169555GO:0009154
GeneOntologyBiologicalProcessdetection of external stimulus

OPN1MW2 OPN1MW3 CACNB3 OPN1LW OPN1MW

9.71e-05173555GO:0009581
GeneOntologyBiologicalProcessorganophosphate catabolic process

ENTPD7 GALT FKRP RPTOR NUDT8 ENTPD4

1.00e-04281556GO:0046434
GeneOntologyBiologicalProcessdetection of abiotic stimulus

OPN1MW2 OPN1MW3 CACNB3 OPN1LW OPN1MW

1.02e-04175555GO:0009582
GeneOntologyBiologicalProcessribonucleoside triphosphate metabolic process

ENTPD7 GALT FKRP RPTOR NDUFB5 ENTPD4

1.19e-04290556GO:0009199
GeneOntologyBiologicalProcesspurine nucleotide catabolic process

GALT FKRP RPTOR NUDT8 ENTPD4

1.23e-04182555GO:0006195
GeneOntologyBiologicalProcessmonocarboxylic acid metabolic process

UGT1A4 UGT1A3 GALT EHHADH FKRP RPTOR UGT1A6 UGT1A5 NUDT8

1.24e-04731559GO:0032787
GeneOntologyBiologicalProcessnucleobase-containing small molecule catabolic process

ENTPD7 GALT ENTPD4

1.31e-0437553GO:0034656
GeneOntologyBiologicalProcesspurine-containing compound catabolic process

GALT FKRP RPTOR NUDT8 ENTPD4

1.43e-04188555GO:0072523
GeneOntologyBiologicalProcessUDP metabolic process

ENTPD7 ENTPD4

1.45e-047552GO:0046048
GeneOntologyBiologicalProcesspyrimidine ribonucleoside diphosphate metabolic process

ENTPD7 ENTPD4

1.45e-047552GO:0009193
GeneOntologyBiologicalProcessnucleoside triphosphate metabolic process

ENTPD7 GALT FKRP RPTOR NDUFB5 ENTPD4

1.63e-04307556GO:0009141
GeneOntologyBiologicalProcesscellular response to radiation

OPN1MW2 OPN1MW3 OPN1LW EIF2AK4 OPN1MW

1.66e-04194555GO:0071478
GeneOntologyBiologicalProcessnucleobase-containing small molecule metabolic process

ENTPD7 SLC4A7 GALT EHHADH FKRP RPTOR NUDT8 NDUFB5 ENTPD4

1.78e-04767559GO:0055086
GeneOntologyBiologicalProcesscarbohydrate derivative catabolic process

ENTPD7 GALT FKRP RPTOR NUDT8 ENTPD4

2.14e-04323556GO:1901136
GeneOntologyBiologicalProcesspyrimidine nucleoside diphosphate metabolic process

ENTPD7 ENTPD4

2.48e-049552GO:0009138
GeneOntologyBiologicalProcessvitamin D3 metabolic process

UGT1A4 UGT1A3

2.48e-049552GO:0070640
GeneOntologyBiologicalProcesspurine nucleoside diphosphate catabolic process

GALT FKRP RPTOR ENTPD4

2.68e-04117554GO:0009137
GeneOntologyBiologicalProcesspurine ribonucleoside diphosphate catabolic process

GALT FKRP RPTOR ENTPD4

2.68e-04117554GO:0009181
GeneOntologyBiologicalProcesscarbohydrate derivative metabolic process

ENTPD7 GALT EHHADH FKRP RPTOR HS3ST6 CHST2 NUDT8 POGLUT2 NDUFB5 ENTPD4

3.33e-0412265511GO:1901135
GeneOntologyBiologicalProcesscarboxylic acid metabolic process

UGT1A4 UGT1A3 GALT EHHADH FKRP RPTOR UGT1A6 UGT1A5 NUDT8 GSTO2

3.61e-0410355510GO:0019752
GeneOntologyBiologicalProcesspyrimidine ribonucleotide catabolic process

ENTPD7 ENTPD4

3.78e-0411552GO:0009222
GeneOntologyBiologicalProcesspurine nucleoside diphosphate metabolic process

GALT FKRP RPTOR ENTPD4

4.25e-04132554GO:0009135
GeneOntologyBiologicalProcesspurine ribonucleoside diphosphate metabolic process

GALT FKRP RPTOR ENTPD4

4.25e-04132554GO:0009179
GeneOntologyBiologicalProcesspyrimidine nucleotide metabolic process

ENTPD7 SLC4A7 ENTPD4

4.27e-0455553GO:0006220
GeneOntologyBiologicalProcesspositive regulation of cytokinesis

OPN1MW2 OPN1LW OPN1MW

4.27e-0455553GO:0032467
GeneOntologyBiologicalProcessoxoacid metabolic process

UGT1A4 UGT1A3 GALT EHHADH FKRP RPTOR UGT1A6 UGT1A5 NUDT8 GSTO2

4.29e-0410585510GO:0043436
GeneOntologyBiologicalProcesscellular response to abiotic stimulus

OPN1MW2 OPN1MW3 RPTOR OPN1LW EIF2AK4 OPN1MW

4.48e-04371556GO:0071214
GeneOntologyBiologicalProcesscellular response to environmental stimulus

OPN1MW2 OPN1MW3 RPTOR OPN1LW EIF2AK4 OPN1MW

4.48e-04371556GO:0104004
GeneOntologyBiologicalProcessorganic acid metabolic process

UGT1A4 UGT1A3 GALT EHHADH FKRP RPTOR UGT1A6 UGT1A5 NUDT8 GSTO2

4.49e-0410645510GO:0006082
GeneOntologyBiologicalProcessnucleobase-containing compound catabolic process

ENTPD7 PDE12 GALT FKRP RPTOR NUDT8 DND1 ENTPD4

4.84e-04696558GO:0034655
GeneOntologyBiologicalProcessCTP metabolic process

ENTPD7 ENTPD4

9.25e-0417552GO:0046036
GeneOntologyBiologicalProcesspurine ribonucleoside triphosphate metabolic process

ENTPD7 GALT FKRP RPTOR NDUFB5

9.32e-04283555GO:0009205
GeneOntologyBiologicalProcesspurine nucleoside triphosphate metabolic process

ENTPD7 GALT FKRP RPTOR NDUFB5

1.06e-03291555GO:0009144
GeneOntologyBiologicalProcesspyrimidine ribonucleoside triphosphate metabolic process

ENTPD7 ENTPD4

1.16e-0319552GO:0009208
GeneOntologyBiologicalProcesspositive regulation of TOR signaling

RPTOR USP32 FNIP1

1.18e-0378553GO:0032008
GeneOntologyCellularComponentphotoreceptor disc membrane

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

6.14e-0726554GO:0097381
GeneOntologyCellularComponentphotoreceptor outer segment

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

2.08e-04111554GO:0001750
GeneOntologyCellularComponentphotoreceptor cell cilium

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

4.91e-04139554GO:0097733
GeneOntologyCellularComponent9+0 non-motile cilium

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

7.04e-04153554GO:0097731
HumanPhenoBlue cone monochromacy

OPN1LW OPN1MW

1.32e-052192HP:0007939
HumanPhenoCone monochromacy

OPN1LW OPN1MW

1.32e-052192HP:0011517
HumanPhenoReduced OCT-measured foveal thickness

OPN1LW OPN1MW

3.95e-053192HP:0030619
HumanPhenoAbnormal OCT-measured foveal thickness

OPN1LW OPN1MW

7.87e-054192HP:0030617
MousePhenoabnormal eye physiology

OPN1MW2 OPN1MW3 SLC4A7 FKRP LPA L1CAM OPN1LW ELP1 NXNL2

4.17e-05606409MP:0005253
MousePhenoabnormal b-wave shape

OPN1MW2 OPN1MW3 FKRP OPN1LW

9.85e-0585404MP:0012035
MousePhenoabnormal b-wave amplitude

OPN1MW2 OPN1MW3 FKRP OPN1LW

9.85e-0585404MP:0012031
MousePhenoabnormal vision

OPN1MW2 OPN1MW3 SLC4A7 OPN1LW

1.18e-0489404MP:0002090
DomainOpsin_red/grn

OPN1MW3 OPN1LW OPN1MW

2.28e-083543IPR000378
DomainUDPGT

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.60e-0721544PF00201
DomainUDPGT

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.60e-0721544PS00375
DomainUDP_glucos_trans

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.60e-0721544IPR002213
DomainOPSIN

OPN1MW3 OPN1LW OPN1MW

2.70e-0610543PS00238
DomainOpsin

OPN1MW3 OPN1LW OPN1MW

3.71e-0611543IPR001760
DomainGDA1_CD39_NTPase

ENTPD7 ENTPD4

2.27e-048542IPR000407
DomainGDA1_CD39

ENTPD7 ENTPD4

2.27e-048542PF01150
DomainGDA1_CD39_NTPASE

ENTPD7 ENTPD4

2.27e-048542PS01238
DomainSulfotransferase_dom

HS3ST6 CHST2

4.85e-0336542IPR000863
DomainSulfotransfer_1

HS3ST6 CHST2

4.85e-0336542PF00685
DomainGlutathione-S-Trfase_C-like

MTX2 GSTO2

5.68e-0339542IPR010987
Domain-

MTX2 GSTO2

5.68e-03395421.20.1050.10
PathwayREACTOME_GLUCURONIDATION

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.95e-0725444M17787
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.95e-0725444M605
PathwayWP_GLUCURONIDATION

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.17e-0626444M39404
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

UGT1A4 UGT1A3 UGT1A6 UGT1A5 HS3ST6 CHST2 GSTO2

1.41e-06183447M39588
PathwayREACTOME_THE_RETINOID_CYCLE_IN_CONES_DAYLIGHT_VISION

OPN1MW2 OPN1MW3 OPN1LW

1.57e-068443MM14880
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.60e-0628444M19580
PathwayKEGG_METABOLISM_OF_XENOBIOTICS_BY_CYTOCHROME_P450

UGT1A4 UGT1A3 UGT1A6 UGT1A5 GSTO2

2.44e-0670445M16794
PathwayKEGG_DRUG_METABOLISM_CYTOCHROME_P450

UGT1A4 UGT1A3 UGT1A6 UGT1A5 GSTO2

2.81e-0672445M9257
PathwayREACTOME_OPSINS

OPN1MW2 OPN1MW3 OPN1LW

3.35e-0610443MM15063
PathwayWP_METAPATHWAY_BIOTRANSFORMATION

UGT1A4 UGT1A3 UGT1A5 HS3ST6 CHST2 GSTO2

7.44e-06153446MM15844
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.68e-0641444M7399
PathwayREACTOME_ASPIRIN_ADME

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.02e-0544444M45014
PathwayBIOCARTA_CD40_PATHWAY

ELP1 TNFAIP3 CHUK

1.26e-0515443M16697
PathwayREACTOME_ATORVASTATIN_ADME

UGT1A4 UGT1A3 UGT1A5

1.26e-0515443MM15697
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.85e-0551444M17726
PathwayBIOCARTA_TNFR2_PATHWAY

ELP1 TNFAIP3 CHUK

1.87e-0517443M10082
PathwayBIOCARTA_TNFR2_PATHWAY

ELP1 TNFAIP3 CHUK

1.87e-0517443MM1517
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.00e-0552444M14171
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A4 UGT1A3 UGT1A6 UGT1A5 GSTO2

2.15e-05109445M18788
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.51e-0555444M14933
PathwayREACTOME_HEME_DEGRADATION

UGT1A4 UGT1A3 UGT1A5

3.12e-0520443MM14721
PathwayKEGG_RETINOL_METABOLISM

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.58e-0564444M9488
PathwayREACTOME_PREDNISONE_ADME

UGT1A4 UGT1A3 UGT1A5

4.81e-0523443MM16639
PathwayREACTOME_GLUCURONIDATION

UGT1A4 UGT1A3 UGT1A5

5.49e-0524443MM14599
PathwayWP_GLUCURONIDATION

UGT1A4 UGT1A3 UGT1A5

6.22e-0525443MM15820
PathwayWP_CONSTITUTIVE_ANDROSTANE_RECEPTOR_PATHWAY

UGT1A4 EHHADH UGT1A6

1.20e-0431443M39476
PathwayREACTOME_METABOLISM_OF_PORPHYRINS

UGT1A4 UGT1A3 UGT1A5

1.32e-0432443MM14719
PathwayREACTOME_THE_RETINOID_CYCLE_IN_CONES_DAYLIGHT_VISION

OPN1LW OPN1MW

1.98e-047442M27157
PathwayWP_CATABOLISM_OF_SKELETAL_MUSCLE_IN_CACHEXIA

RPTOR SMAD4 CHUK

2.59e-0440443M48337
PathwayREACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS

ENTPD7 ENTPD4

2.63e-048442M27737
PathwayREACTOME_PHOSPHATE_BOND_HYDROLYSIS_BY_NTPDASE_PROTEINS

ENTPD7 ENTPD4

2.63e-048442MM15486
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

UGT1A4 UGT1A3 UGT1A5 GSTO2

3.37e-04107444MM14595
PathwayREACTOME_OPSINS

OPN1LW OPN1MW

3.38e-049442M6285
PathwayREACTOME_DRUG_ADME

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.62e-04109444M45012
PathwayREACTOME_ASPIRIN_ADME

UGT1A4 UGT1A3 UGT1A5

3.67e-0445443MM15694
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

UGT1A4 UGT1A3 UGT1A6 UGT1A5 GSTO2

5.85e-04220445M10320
PathwayREACTOME_RETINOID_CYCLE_DISEASE_EVENTS

OPN1LW OPN1MW

7.27e-0413442M29612
PathwayBIOCARTA_CD40_PATHWAY

TNFAIP3 CHUK

8.46e-0414442MM1362
PathwayWP_ESTROGEN_METABOLISM_WP697

UGT1A3 UGT1A6

1.41e-0318442M39424
PathwayWP_IL18_SIGNALING

SLC4A7 RPTOR TBX21 TNFAIP3 CHUK

1.54e-03273445M39818
PathwayBIOCARTA_NFKB_PATHWAY

TNFAIP3 CHUK

1.93e-0321442MM1444
PathwayBIOCARTA_NFKB_PATHWAY

TNFAIP3 CHUK

1.93e-0321442M15285
PathwayWP_VITAMIN_D_IN_INFLAMMATORY_DISEASES

SMAD4 CHUK

2.11e-0322442M39773
PathwayBIOCARTA_NTHI_PATHWAY

SMAD4 CHUK

2.11e-0322442MM1443
PathwayWP_ESTROGEN_METABOLISM

UGT1A3 UGT1A5

2.11e-0322442MM15888
PathwayBIOCARTA_NTHI_PATHWAY

SMAD4 CHUK

2.31e-0323442M2821
PathwayPID_NFKAPPAB_CANONICAL_PATHWAY

TNFAIP3 CHUK

2.31e-0323442M37
Pubmed

Human L- and M-opsins restore M-cone function in a mouse model for human blue cone monochromacy.

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

6.03e-12456429386880
Pubmed

Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

3.01e-1155642937147
Pubmed

Genetic and physical mapping of a gene encoding a methyl CpG binding protein, Mecp2, to the mouse X chromosome.

OPN1MW2 OPN1MW3 L1CAM OPN1LW

2.10e-1075648001979
Pubmed

Mapping of the murine tbl1 gene reveals a new rearrangement between mouse and human X Chromosomes.

OPN1MW2 OPN1MW3 L1CAM OPN1LW

2.10e-1075649880679
Pubmed

A genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.55e-10956422511988
Pubmed

A novel complex locus UGT1 encodes human bilirubin, phenol, and other UDP-glucuronosyltransferase isozymes with identical carboxyl termini.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.55e-1095641339448
Pubmed

Association of SNPs in the UGT1A gene cluster with total bilirubin and mortality in the Diabetes Heart Study.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.26e-091056423642732
Pubmed

UDP-glucuronosyltransferases.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.26e-091056411465080
Pubmed

Linkage of a gene for neural cell adhesion molecule, L1 (CamL1) to the Rsvp region of the mouse X chromosome.

OPN1MW2 OPN1MW3 L1CAM OPN1LW

1.26e-09105641964443
Pubmed

A genome-wide association study for serum bilirubin levels and gene-environment interaction in a Chinese population.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.26e-091056423371916
Pubmed

A genome-wide association study of total bilirubin and cholelithiasis risk in sickle cell anemia.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.26e-091056422558097
Pubmed

Comparative mapping on the mouse and human X chromosomes of a human cDNA clone encoding the vasopressin renal-type receptor (AVP2R).

OPN1MW2 OPN1MW3 L1CAM OPN1LW

1.26e-09105648449515
Pubmed

Physical mapping of the loci Gabra3, DXPas8, CamL1, and Rsvp in a region of the mouse X chromosome homologous to human Xq28.

OPN1MW2 OPN1MW3 L1CAM OPN1LW

1.26e-09105641684949
Pubmed

Genetic and physical mapping of the biglycan gene on the mouse X chromosome.

OPN1MW2 OPN1MW3 L1CAM OPN1LW

2.95e-09125648093671
Pubmed

Common variants in the SLCO1B3 locus are associated with bilirubin levels and unconjugated hyperbilirubinemia.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.95e-091256419419973
Pubmed

Thirteen UDPglucuronosyltransferase genes are encoded at the human UGT1 gene complex locus.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.95e-091256411434514
Pubmed

Molecular determinants of human red/green color discrimination.

OPN1MW2 OPN1LW OPN1MW

3.95e-0935638185948
Pubmed

X-linked cone dystrophy caused by mutation of the red and green cone opsins.

OPN1MW2 OPN1LW OPN1MW

3.95e-09356320579627
Pubmed

Expression of red/green-cone opsin mutants K82E, P187S, M273K result in unique pathobiological perturbations to cone structure and function.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356338410159
Pubmed

Chloride-dependent spectral tuning mechanism of L-group cone visual pigments.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356323350963
Pubmed

Distinct contributions of rod, cone, and melanopsin photoreceptors to encoding irradiance.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356320471354
Pubmed

Multiple hypothalamic cell populations encoding distinct visual information.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356321224225
Pubmed

Circadian Regulation of the Rod Contribution to Mesopic Vision in Mice.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356336216501
Pubmed

Spectral tuning of a circadian photopigment in a subterranean 'blind' mammal (Spalax ehrenbergi).

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356310567724
Pubmed

Extensive cone-dependent spectral opponency within a discrete zone of the lateral geniculate nucleus supporting mouse color vision.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356334111401
Pubmed

Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356314500905
Pubmed

Gene-based Therapy in a Mouse Model of Blue Cone Monochromacy.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356328751656
Pubmed

Rescue of M-cone Function in Aged Opn1mw-/- Mice, a Model for Late-Stage Blue Cone Monochromacy.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356331469404
Pubmed

The molecular genetics and evolution of red and green color vision in vertebrates.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356311545071
Pubmed

Mechanisms of spectral tuning in the mouse green cone pigment.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-0935639238068
Pubmed

Emergence of novel color vision in mice engineered to express a human cone photopigment.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356317379811
Pubmed

Co-expression of murine opsins facilitates identifying the site of cone adaptation.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-09356312511072
Pubmed

The Pem homeobox gene is X-linked and exclusively expressed in extraembryonic tissues during early murine development.

OPN1MW2 OPN1MW3 OPN1LW

3.95e-0935637958444
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.26e-091356422085899
Pubmed

Genome-wide analysis of hepatic lipid content in extreme obesity.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.26e-091356425246029
Pubmed

Mayo Genome Consortia: a genotype-phenotype resource for genome-wide association studies with an application to the analysis of circulating bilirubin levels.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.96e-091456421646302
Pubmed

Human UDP-glucuronosyltransferases: metabolism, expression, and disease.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.96e-091456410836148
Pubmed

Multiple variable first exons: a mechanism for cell- and tissue-specific gene regulation.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.96e-091456414672974
Pubmed

Genetic mapping of the mouse X chromosome in the region homologous to human Xq27-Xq28.

OPN1MW2 OPN1MW3 L1CAM OPN1LW

5.96e-09145641674728
Pubmed

The UDP glycosyltransferase gene superfamily: recommended nomenclature update based on evolutionary divergence.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.96e-09145649295054
Pubmed

A 2.3-Mb yeast artificial chromosome contig spanning from Gabra3 to G6pd on the mouse X chromosome.

OPN1MW2 OPN1MW3 L1CAM OPN1LW

8.12e-09155648088815
Pubmed

Genome-wide association meta-analysis for total serum bilirubin levels.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.08e-081656419414484
Pubmed

Genome-wide association of serum bilirubin levels in Korean population.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.41e-081756420639394
Pubmed

Visual responses in the dorsal lateral geniculate nucleus at early stages of retinal degeneration in rd1 PDE6β mice.

OPN1MW2 OPN1MW3 OPN1LW

1.58e-08456331461375
Pubmed

Murine and bovine blue cone pigment genes: cloning and characterization of two new members of the S family of visual pigments.

OPN1MW2 OPN1MW3 OPN1LW

1.58e-0845638088841
Pubmed

Modulation of Fast Narrowband Oscillations in the Mouse Retina and dLGN According to Background Light Intensity.

OPN1MW2 OPN1MW3 OPN1LW

1.58e-08456328103478
Pubmed

Molecular biology of the visual pigments.

OPN1MW2 OPN1LW OPN1MW

1.58e-0845633303660
Pubmed

Cones Support Alignment to an Inconsistent World by Suppressing Mouse Circadian Responses to the Blue Colors Associated with Twilight.

OPN1MW2 OPN1MW3 OPN1LW

1.58e-08456331846668
Pubmed

Melanopsin-driven increases in maintained activity enhance thalamic visual response reliability across a simulated dawn.

OPN1MW2 OPN1MW3 OPN1LW

1.58e-08456326438865
Pubmed

Light/dark translocation of alphatransducin in mouse photoreceptor cells expressing G90D mutant opsin.

OPN1MW2 OPN1MW3 OPN1LW

1.58e-08456317249565
Pubmed

Structural and functional rescue of cones carrying the most common cone opsin C203R missense mutation.

OPN1MW2 OPN1MW3 OPN1LW

1.58e-08456338060327
Pubmed

Contribution of M-opsin-based color vision to refractive development in mice.

OPN1MW2 OPN1MW3 OPN1LW

1.58e-08456334126082
Pubmed

Physiological features of the S- and M-cone photoreceptors of wild-type mice from single-cell recordings.

OPN1MW2 OPN1MW3 OPN1LW

1.58e-08456316567464
Pubmed

S-opsin knockout mice with the endogenous M-opsin gene replaced by an L-opsin variant.

OPN1MW2 OPN1MW3 OPN1LW

1.58e-08456324801621
Pubmed

Melanopsin Contributions to the Representation of Images in the Early Visual System.

OPN1MW2 OPN1MW3 OPN1LW

1.58e-08456328528909
Pubmed

Melanopsin-driven light adaptation in mouse vision.

OPN1MW2 OPN1MW3 OPN1LW

1.58e-08456325308073
Pubmed

A genome-wide assessment of variability in human serum metabolism.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.29e-081956423281178
Pubmed

Noncoding Mutations in a Thyroid Hormone Receptor Gene That Impair Cone Photoreceptor Function.

OPN1MW2 OPN1MW3 OPN1LW

3.94e-08556336631163
Pubmed

Using Silent Substitution to Track the Mesopic Transition From Rod- to Cone-Based Vision in Mice.

OPN1MW2 OPN1MW3 OPN1LW

3.94e-08556326818794
Pubmed

A common integration locus in type B retrovirus-induced thymic lymphomas.

OPN1MW2 OPN1MW3 OPN1LW

3.94e-0855631333116
Pubmed

A distinct contribution of short-wavelength-sensitive cones to light-evoked activity in the mouse pretectal olivary nucleus.

OPN1MW2 OPN1MW3 OPN1LW

3.94e-08556322090509
Pubmed

Comparative sequence analysis of the MECP2-locus in human and mouse reveals new transcribed regions.

OPN1MW2 OPN1MW3 OPN1LW

3.94e-08556310723722
Pubmed

Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors.

OPN1MW2 OPN1MW3 OPN1LW

3.94e-08556327033727
Pubmed

Melanopsin-based brightness discrimination in mice and humans.

OPN1MW2 OPN1MW3 OPN1LW

3.94e-08556322633808
Pubmed

The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning.

OPN1MW2 OPN1MW3 OPN1LW

3.94e-08556311055434
Pubmed

Enhancer/promoter activities of the long/middle wavelength-sensitive opsins of vertebrates mediated by thyroid hormone receptor β2 and COUP-TFII.

OPN1MW2 OPN1MW3 OPN1LW

3.94e-08556324058409
Pubmed

Variations in photoreceptor throughput to mouse visual cortex and the unique effects on tuning.

OPN1MW2 OPN1MW3 OPN1LW

3.94e-08556334099749
Pubmed

Genetic determinants influencing human serum metabolome among African Americans.

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.25e-082456424625756
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

UGT1A4 UGT1A3 UGT1A6 UGT1A5 CHST2

7.47e-086656519898482
Pubmed

Functional comparison of rod and cone Gα(t) on the regulation of light sensitivity.

OPN1MW2 OPN1MW3 OPN1LW

7.88e-08656323288843
Pubmed

Analysis of inherited genetic variations at the UGT1 locus in the French-Canadian population.

UGT1A4 UGT1A3 UGT1A6

7.88e-08656319204906
Pubmed

Reduced levels of dystrophin associated proteins in the brains of mice deficient for Dp71.

OPN1MW2 OPN1MW3 OPN1LW

7.88e-0865638872469
Pubmed

A thyroid hormone receptor that is required for the development of green cone photoreceptors.

OPN1MW2 OPN1MW3 OPN1LW

7.88e-08656311138006
Pubmed

Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase.

OPN1MW2 OPN1MW3 OPN1LW

7.88e-08656310395695
Pubmed

Transient expression of thyroid hormone nuclear receptor TRbeta2 sets S opsin patterning during cone photoreceptor genesis.

OPN1MW2 OPN1MW3 OPN1LW

7.88e-08656317436273
Pubmed

Telomere-related markers for the pseudoautosomal region of the mouse genome.

OPN1MW2 OPN1MW3 OPN1LW

7.88e-0865631549575
Pubmed

Retarded developmental expression and patterning of retinal cone opsins in hypothyroid mice.

OPN1MW2 OPN1MW3 OPN1LW

1.38e-07756318974269
Pubmed

NeuroD1 regulates expression of thyroid hormone receptor 2 and cone opsins in the developing mouse retina.

OPN1MW2 OPN1MW3 OPN1LW

1.38e-07756318199774
Pubmed

Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.

OPN1MW2 OPN1MW3 OPN1LW

1.38e-0775638378320
Pubmed

Rod Photoreceptor Activation Alone Defines the Release of Dopamine in the Retina.

OPN1MW2 OPN1MW3 OPN1LW

1.38e-07756330799247
Pubmed

Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta.

OPN1MW2 OPN1MW3 OPN1LW

1.38e-07756316574740
Pubmed

Rods progressively escape saturation to drive visual responses in daylight conditions.

OPN1MW2 OPN1MW3 OPN1LW

1.38e-07756329180667
Pubmed

Cloning and distribution of myosin 3B in the mouse retina: differential distribution in cone outer segments.

OPN1MW2 OPN1MW3 OPN1LW

1.38e-07756319332056
Pubmed

Oligomerization of the UDP-glucuronosyltransferase 1A proteins: homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation.

UGT1A4 UGT1A3 UGT1A6

2.20e-07856317179145
Pubmed

Localization of the mdx mutation within the mouse dystrophin gene.

OPN1MW2 OPN1MW3 OPN1LW

2.20e-0785632903046
Pubmed

Alternatively spliced products of the UGT1A gene interact with the enzymatically active proteins to inhibit glucuronosyltransferase activity in vitro.

UGT1A4 UGT1A3 UGT1A6

2.20e-07856320610558
Pubmed

Genetic mapping on the mouse X chromosome of human cDNA clones for the fragile X and Hunter syndromes.

OPN1MW2 OPN1MW3 OPN1LW

2.20e-0785631572654
Pubmed

Two transcription factors can direct three photoreceptor outcomes from rod precursor cells in mouse retinal development.

OPN1MW2 OPN1MW3 OPN1LW

2.20e-07856321813673
Pubmed

Simultaneous evaluation of six human glucuronidation activities in liver microsomes using liquid chromatography-tandem mass spectrometry.

UGT1A4 UGT1A3 UGT1A6

2.20e-07856322579593
Pubmed

X-chromosome gene order in different Mus species crosses.

OPN1MW2 OPN1MW3 OPN1LW

2.20e-0785633416629
Pubmed

The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis.

OPN1MW2 OPN1MW3 OPN1LW

2.20e-07856312651948
Pubmed

Transcriptional profiling of murine retinas undergoing semi-synchronous cone photoreceptor differentiation.

OPN1MW2 OPN1MW3 OPN1LW

2.20e-07856331163126
Pubmed

Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors.

OPN1MW2 OPN1MW3 OPN1LW

2.20e-07856320203194
Pubmed

Tubby is required for trafficking G protein-coupled receptors to neuronal cilia.

OPN1MW2 OPN1MW3 OPN1LW

2.20e-07856323351594
Pubmed

A retinitis pigmentosa GTPase regulator (RPGR)-deficient mouse model for X-linked retinitis pigmentosa (RP3).

OPN1MW2 OPN1MW3 OPN1LW

2.20e-07856310725384
Pubmed

Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina.

OPN1MW2 OPN1MW3 OPN1LW

2.20e-07856316043864
Pubmed

Nr2e3 functional domain ablation by CRISPR-Cas9D10A identifies a new isoform and generates retinitis pigmentosa and enhanced S-cone syndrome models.

OPN1MW2 OPN1MW3 OPN1LW

2.20e-07856333007388
Pubmed

Linkage of amelogenin (Amel) to the distal portion of the mouse X chromosome.

OPN1MW2 OPN1MW3 OPN1LW

2.20e-0785631675194
Pubmed

Retinal dystrophy resulting from ablation of RXR alpha in the mouse retinal pigment epithelium.

OPN1MW2 OPN1MW3 OPN1LW

3.30e-07956314742273
Pubmed

Feedback induction of a photoreceptor-specific isoform of retinoid-related orphan nuclear receptor β by the rod transcription factor NRL.

OPN1MW2 OPN1MW3 OPN1LW

3.30e-07956325296752
Cytoband2q37

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.09e-08315642q37
CytobandEnsembl 112 genes in cytogenetic band chrXq28

OPN1MW2 OPN1MW3 L1CAM OPN1LW OPN1MW

6.46e-06213565chrXq28
CytobandXq28

OPN1MW2 L1CAM OPN1LW OPN1MW

6.56e-05176564Xq28
CytobandEnsembl 112 genes in cytogenetic band chr2q37

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.72e-04226564chr2q37
Cytoband15q15.1

EIF2AK4 BAHD1

1.53e-034756215q15.1
GeneFamilyOpsin receptors

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

5.42e-0911384215
GeneFamilyUDP glucuronosyltransferases

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.72e-0732384363
GeneFamilySulfotransferases, membrane bound

HS3ST6 CHST2

2.73e-0337382763
GeneFamilyCyclins|F-boxes other

FBXO38 FBXO46

3.03e-0339382560
DrugAC1MRQNQ

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.80e-099554CID003522271
DrugDHPASiU

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.80e-099554CID000197602
DrugChebi:32663

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.80e-099554CID005460873
Drug3-iodophenol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.80e-099554CID000012272
DrugAC1L4J7U

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.80e-099554CID000186631
DrugDiclofenac

ENTPD7 UGT1A4 UGT1A3 UGT1A6 POLG TBX21 CSTF3 EIF2AK4 TNFAIP3 ENTPD4 SMAD4 CHUK

8.89e-095705512ctd:D004008
Drug4-nitrophenyl)imidazole

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.93e-0911554CID000123155
DrugAC1O5XMV

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.93e-0911554CID006442661
DrugN-OH-DABZ

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.49e-0812554CID000051366
Drug1-O-beta-D-glucopyranosyl-D-mannitol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.49e-0812554CID000088735
Drug2,4,6-TCB

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.49e-0812554CID000037247
Drug7,7,7-triphenylheptanoic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.49e-0812554CID000276709
Drugnonanoyl-N-methylglucamide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.49e-0812554CID000160090
Drugtritanol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.14e-0813554CID000006457
Drug5-azido-UDP-glucuronic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.14e-0813554CID003081279
Drugcotinine-N-glucuronide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.14e-0813554CID000000411
Drugpropranolol glucuronide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.00e-0814554CID000119515
DrugPCB-61

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.00e-0814554CID000036401
Drug8-azaguanine

UGT1A4 UGT1A3 UGT1A6 UGT1A5 L1CAM TNFAIP3

3.37e-0878556CID000008646
Drug2,2',3,5,5'-pentachlorobiphenyl

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.08e-0815554CID000040469
Drugcoumarin-3-carboxylic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.08e-0815554CID000010752
Drugsulforaphane nitrile

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.08e-0815554CID000543743
Drugafloqualone

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.08e-0815554CID000002040
Drugnaphthyl sulphate

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.08e-0815554CID000114775
Drugquercetin-3,4'-diglucoside

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.43e-0816554CID005320835
Drug1'-hydroxyestragole

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.43e-0816554CID000040003
Drugbilirubin-phosphate

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.43e-0816554CID005497144
Drug3 beta,5 alpha,25R)- 3-hydroxyspirostan-12-one

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.08e-0817554CID000003573
Drug6-hydroxychrysene

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.08e-0817554CID000037766
Drugethyl-beta-D-6-glucosiduronic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.09e-0818554CID000152226
DrugBr 2

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.09e-0818554CID003060900
DrugSureCN12722713

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.09e-0818554CID005488034
Drug2,3,7-trichlorodibenzo-p-dioxin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.09e-0818554CID000036614
DrugApApG

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.09e-0818554CID003081975
DrugC1 11-32

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.09e-0818554CID000443077
DrugC11131

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.09e-0818554CID000443076
Drugalmokalant

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.15e-0719554CID003033962
Drug9-OH-risperidone

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.15e-0719554CID000475100
Drug5alpha-spirostan-3beta-ol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.15e-0719554CID000091433
Drugphenanthroline

UGT1A4 UGT1A3 UGT1A6 UGT1A5 GSTO2

1.33e-0750555CID000067473
Drugtectochrysin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.43e-0720554CID005281954
DrugAC1L1OBF

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.43e-0720554CID000032736
Drug4'-hydroxydiclofenac

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.43e-0720554CID000116545
Drug(+/-)-Abacavir

UGT1A4 UGT1A3 UGT1A6 UGT1A5 POLG

1.47e-0751555CID000001971
Drugestriol-16-glucuronide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.77e-0721554CID000122281
Drugdulcin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.77e-0721554CID000009013
DrugBenzamidoxime hydrochloride

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.77e-0721554CID000069186
DrugHCG 004

UGT1A4 UGT1A3 UGT1A6 UGT1A5 CHUK

1.97e-0754555CID000064928
Drugamonafide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.16e-0722554CID000050515
DrugN-methylpiperazine

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.16e-0722554CID000053167
Drugamidoxime

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.61e-0723554CID000465967
Drugestradiol-3-glucuronide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.61e-0723554CID000066651
Drugphenanthridine

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.61e-0723554CID000009189
Drugurochloralic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5 PAQR7

3.10e-0759555CID003036914
Drugacetaminophen glucuronide

UGT1A4 UGT1A3 GALT UGT1A6 UGT1A5

3.10e-0759555CID000083944
DrugAS-3201

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.12e-0724554CID000153948
Drug3-OH

UGT1A4 UGT1A3 RPTOR UGT1A6 UGT1A5

3.67e-0761555CID000068152
Drug5-MOP

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.71e-0725554CID000002355
DrugAzMC

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.71e-0725554CID000064986
DrugN-acetylbenzidine

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.71e-0725554CID000018787
Drug5,6-benzoquinoline

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.71e-0725554CID000006796
DrugN-phenylmaleimide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.71e-0725554CID000013662
DrugDiMeIQx

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.13e-0727554CID000104739
Drugdiflunisal

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.13e-0727554CID000003059
DrugN-hydroxy-4-aminobiphenyl

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.98e-0728554CID000081261
DrugCARMINE

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.98e-0728554CID000014749
Drugerucin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.98e-0728554CID000078160
DrugH-Ni

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.98e-0728554CID000445665
DrugAC1L1JAL

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.92e-0729554CID000004954
Drug7-hydroxy-4-trifluoromethylcoumarin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.92e-0729554CID005375667
Drugtrans-3'-hydroxycotinine

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.92e-0729554CID000000414
Drug7-hydroxycoumarin glucuronide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.92e-0729554CID000125641
Drugiberin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.92e-0729554CID000010455
Drugtolcapone

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.97e-0730554CID004659569
Drugparicalcitol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.97e-0730554CID005281104
DrugAC1L9E0Q

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.97e-0730554CID000443095
Drugdihydroartemisinin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

7.97e-0730554CID000107770
Drug4-ethylphenol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.13e-0731554CID000031242
DrugPCB 156

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.13e-0731554CID000038019
Drug4'-HPPH

UGT1A4 UGT1A3 UGT1A6 UGT1A5

9.13e-0731554CID000017732
Drugindole-2-carboxylic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.04e-0632554CID000072899
DrugNNAL

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.04e-0632554CID000104856
DrugMuracein C

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.04e-0632554CID003086323
Drug16-epiestriol

UGT1A4 UGT1A3 UGT1A6 UGT1A5 TNFAIP3

1.18e-0677555CID000003269
DrugAC1Q6OQG

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.18e-0633554CID000009686
DrugR(-)-Denopamine

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.18e-0633554CID000003818
Drug6-methylsalicylic acid

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.18e-0633554CID000011279
DrugBP-3,6-quinol

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.18e-0633554CID000119292
Drugnorbuprenorphine

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.18e-0633554CID000114976
Druggeniposide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.18e-0633554CID000107848
Drugestragole

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.34e-0634554CID000008815
DrugAC1NOWCJ

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.51e-0635554CID005120112
Drug3-[(3S,5R,10S,13R,14S,17R)-3-[(2S,4R,5R,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-14-hydroxy-10,13-dimethyl-1,2,3,4,5,6,7,8,9,11,12,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl]-2H-furan-5-one

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.51e-0635554CID010436171
Drugestrone-3-glucuronide

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.51e-0635554CID000115255
Drugacridine

UGT1A4 UGT1A3 UGT1A6 UGT1A5 POLG

1.52e-0681555CID000009215
DrugAC1L9DGV

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.69e-0636554CID000417381
Drugmuraglitazar

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.69e-0636554CID000206044
Druganisole

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.69e-0636554CID000007519
Drugglucoraphanin

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.69e-0636554CID000656556
Drugbevirimat

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.69e-0636554CID000457928
Diseaseblue cone monochromacy (implicated_via_orthology)

OPN1MW2 OPN1MW3 OPN1LW OPN1MW

9.27e-124534DOID:0050679 (implicated_via_orthology)
DiseaseX-11793--oxidized bilirubin measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.46e-108534EFO_0021260
DiseaseSuccinimide measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.46e-108534EFO_0022118
DiseaseX-11530 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.46e-108534EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.46e-108534EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.46e-108534EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.46e-108534EFO_0800696
DiseaseX-10458 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.46e-108534EFO_0800692
DiseaseX-24849 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.46e-108534EFO_0800909
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.46e-108534EFO_0802740
DiseaseX-16946 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.46e-108534EFO_0800766
DiseaseX-11442 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.16e-099534EFO_0021236
DiseaseX-11441 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.16e-099534EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.16e-099534EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.16e-099534EFO_0801037
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.16e-099534EFO_0802127
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.16e-099534EFO_0801036
DiseaseX-11880 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.16e-099534EFO_0800698
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.16e-099534EFO_0004570, GO_0009410
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.16e-099534EFO_0020691
DiseaseX-21448 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.93e-0910534EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.93e-0910534EFO_0802185
DiseaseX-23974 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.93e-0910534EFO_0800867
Diseasebilirubin measurement, response to tenofovir

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.93e-0910534EFO_0004570, EFO_0009279
DiseaseX-21796 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.03e-0911534EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.03e-0911534EFO_0004570, EFO_0004698
Diseasehistidine betaine (hercynine) measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.03e-0911534EFO_0800972
Diseasealdosterone measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.03e-0911534EFO_0010219
Diseasebiliverdin measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.54e-0912534EFO_0021033
Diseasep-cresol glucuronide measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.54e-0912534EFO_0800079
Diseaseretinol dehydrogenase 16 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

6.55e-0913534EFO_0802007
DiseaseX-21441 measurement

ENTPD7 UGT1A4 UGT1A6 UGT1A5

2.17e-0817534EFO_0800814
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.17e-0817534EFO_0004611, EFO_0007800
Diseaseangiopoietin-related protein 1 measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.79e-0818534EFO_0801382
Diseasetissue factor measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

5.43e-0821534EFO_0010623
Diseasexanthurenate measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.13e-0729534EFO_0010551
Diseaseresponse to dolutegravir

UGT1A4 UGT1A3 UGT1A6 UGT1A5

2.45e-0730534EFO_0600017
Diseasepregnenetriol sulfate measurement

UGT1A4 UGT1A6 UGT1A5

8.94e-0711533EFO_0800586
Diseaseplasma N-desmethylclozapine measurement

UGT1A4 UGT1A6 UGT1A5

8.94e-0711533EFO_0600039
Diseasepregnenetriol disulfate measurement

UGT1A4 UGT1A6 UGT1A5

1.55e-0613533EFO_0800587
DiseaseCone monochromatism

OPN1LW OPN1MW

3.17e-062532C0339537
DiseaseBLUE CONE MONOCHROMACY

OPN1LW OPN1MW

3.17e-062532303700
DiseaseCone monochromatism

OPN1LW OPN1MW

3.17e-062532cv:C0339537
Diseaseblue cone monochromacy (is_implicated_in)

OPN1LW OPN1MW

3.17e-062532DOID:0050679 (is_implicated_in)
DiseaseBORNHOLM EYE DISEASE

OPN1LW OPN1MW

3.17e-062532C3159311
DiseaseAchromatopsia incomplete, X-linked

OPN1LW OPN1MW

3.17e-062532C2931753
DiseaseRed-green dyschromatopsia

OPN1LW OPN1MW

3.17e-062532cv:C0155016
Diseaseurate measurement, spine bone mineral density

UGT1A4 UGT1A3 UGT1A6 UGT1A5

3.66e-0658534EFO_0004531, EFO_0007701
Diseasethyroxine measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.53e-0583534EFO_0005130
Diseasehormone measurement

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.61e-0584534EFO_0004730
Diseasecholelithiasis

UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.93e-0588534EFO_0004799
Diseasegallstones

UGT1A4 UGT1A3 UGT1A6 UGT1A5

4.33e-05108534EFO_0004210
Diseaseserum N-desmethylclozapine measurement

UGT1A6 UGT1A5

8.80e-058532EFO_0600043
Diseaseplasma clozapine measurement

UGT1A6 UGT1A5

8.80e-058532EFO_0600038
DiseaseIdiopathic pulmonary hypertension

EIF2AK4 SMAD4

1.13e-049532C0152171
DiseasePulmonary arterial hypertension

EIF2AK4 SMAD4

1.41e-0410532C2973725
Diseasecolon cancer (is_marker_for)

TNFAIP3 SMAD4 CHUK

1.66e-0459533DOID:219 (is_marker_for)
Disease2-oxo-hept-3-ene-1,7-dioate hydratase activity

EIF2AK4 SMAD4

2.84e-0414532C1150929
DiseaseIdiopathic pulmonary arterial hypertension

EIF2AK4 SMAD4

3.74e-0416532C3203102
DiseaseFamilial primary pulmonary hypertension

EIF2AK4 SMAD4

4.23e-0417532C0340543
Diseasebilirubin measurement

ENTPD7 UGT1A4 UGT1A3 UGT1A6 UGT1A5

1.17e-03442535EFO_0004570
Diseaseapolipoprotein B measurement

UGT1A4 UGT1A3 LPA UGT1A6 UGT1A5 TBX21

1.18e-03663536EFO_0004615
DiseaseCone-Rod Dystrophy 2

OPN1LW OPN1MW

1.25e-0329532C3489532
DiseaseMyopathy

EIF2AK4 SMAD4

1.33e-0330532C0026848
Diseasenon-high density lipoprotein cholesterol measurement

UGT1A4 UGT1A3 LPA UGT1A6 UGT1A5 GLTPD2

1.70e-03713536EFO_0005689

Protein segments in the cluster

PeptideGeneStartEntry
GAPHLRPAAHDLTWY

UGT1A3

471

P35503
LMYPPPLYDAHELWH

ANXA10

86

Q9UJ72
EYLEVYWRATHHPAP

CACNB3

351

P54284
YYNAWIERHERPAGP

EIF2AK4

651

Q9P2K8
LWDYHQHRYLQGVPE

IBA57

216

Q5T440
EGPNYHIAPRWVYHL

OPN1LW

41

P04000
EGPNYHIAPRWVYHL

OPN1MW3

41

P0DN78
YTLPVFLHGPHRVWG

NUDT8

166

Q8WV74
EGPNYHIAPRWVYHL

OPN1MW2

41

P0DN77
GPEGKYPLHYLVWHN

ANKRD13B

11

Q86YJ7
RPIYEPLHTHWPHNF

PAQR7

301

Q86WK9
DAYRAALGPHHPWLV

GLTPD2

216

A6NH11
RIFVYFWPRHNGNPH

ENTPD7

96

Q9NQZ7
AGYRPFLHHLQPFTW

CHUK

216

O15111
IDVVYLHGYGWPRHK

EHHADH

646

Q08426
RWHPKPYHHDLPYGR

FBXO46

546

Q6PJ61
HLYWHPKGGYIRLIQ

PDE12

456

Q6L8Q7
VLGHHPDIWYEAAQY

CSTF3

286

Q12996
EWYYTKHPFGHIPVL

GSTO2

61

Q9H4Y5
PLHYSERHGWGYLVP

POLG

611

P54098
AAPYWLHKPQSHLYG

L1CAM

331

P32004
PYRLHVLCQGWHYLA

ELP1

356

O95163
HPRPHYSWYRNDVPL

JAM3

166

Q9BX67
EGPNYHIAPRWVYHL

OPN1MW

41

P04001
AIYNCPHLHNPYNWI

FBXO38

406

Q6PIJ6
FVWYCYHVGREQPRP

ASPHD2

71

Q6ICH7
THPYNPLWAQLGDLY

FNIP1

496

Q8TF40
WQLHAHYYPPLLRSA

GALT

316

P07902
PEYYDHLPQHHSWVK

DEGS2

281

Q6QHC5
LWYYRPEHLQGGRSP

BAHD1

666

Q8TBE0
TPHWHRRIPLYYPNA

LPA

1416

P08519
HRFWYQVVIPGHPVP

DND1

286

Q8IYX4
NHLHVDLWPFYPRNG

FKRP

411

Q9H9S5
ELHRNHPHLPDGEYW

COL5A3

1546

P25940
GLYAQHLDHWLRYFP

HS3ST6

226

Q96QI5
THARYGSPYPWPLNH

MTX2

141

O75431
HHGPYIPDVLFWCVI

SLC4A7

816

Q9Y6M7
LIHQYCQGYWRHVPP

SEMA3F

741

Q13275
RVFVYCWPRHNGNPH

ENTPD4

101

Q9Y227
PHPGHYWPVHNELAF

SMAD4

296

Q13485
PHWPHLAVGSNDYYI

RPTOR

1311

Q8N122
QPPDWLQGHYLVVRY

CHST2

411

Q9Y4C5
ALAWYHRALGHYQPQ

TTC24

136

A2A3L6
YVARPVHWQPGHTAF

TRMT61B

451

Q9BVS5
LHGAWLALPFHDPYR

NXNL2

86

Q5VZ03
GIYLPLHWPAQECYR

TNFAIP3

231

P21580
GAPHLRPAAHDLTWY

UGT1A5

471

P35504
IPEGYVPEHWEYYKH

NDUFB5

101

O43674
EHFYNELQPWKHYIP

POGLUT2

396

Q6UW63
EHWLYYLDPFLHHVG

SFMBT1

206

Q9UHJ3
PHLRPAAHDLTWYQY

UGT1A6

471

P19224
VRQFHYQAWPDHGVP

PTPRH

976

Q9HD43
VPQAYWLGAPRDHSY

TBX21

381

Q9UL17
YHWYGANLALPRPVI

USP32

571

Q8NFA0
YLATSYRHVVRHWPP

TMEM249

196

Q2WGJ8
GAPHLRPAAHDLTWY

UGT1A4

471

P22310