Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	FZD7 OR52I1 CELSR1 OR14A2 CELSR2 TMEM116 OR2G2 OR13H1 ADGRL1 GPR87 ADGRF4 ADGRF3 FZD2 CHRM3 OR1L3 ADGRL3	1.88e-06	884	90	16	GO:0004930
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	FZD7 OR52I1 CELSR1 CD3G OR14A2 CELSR2 TMEM116 OR2G2 OR13H1 ADGRL1 GPR87 ADGRF4 ADGRF3 GRIN2C FZD2 CHRM3 OR1L3 ADGRL3	2.85e-05	1353	90	18	GO:0004888
GeneOntologyMolecularFunction	histone H4K20 demethylase activity	KDM7A PHF8	1.20e-04	4	90	2	GO:0035575
GeneOntologyMolecularFunction	zinc ion binding	USP49 ADAMTS3 ZPR1 RNF144A SEC24B KDM7A PHF8 ZZEF1 TRIM49B ADAT2 TOP3A TRIM48 TRIM51G	1.74e-04	891	90	13	GO:0008270
GeneOntologyMolecularFunction	histone H4 demethylase activity	KDM7A PHF8	1.99e-04	5	90	2	GO:0141058
GeneOntologyMolecularFunction	histone H3K27me2/H3K27me3 demethylase activity	KDM7A PHF8	1.99e-04	5	90	2	GO:0071558
GeneOntologyMolecularFunction	histone H3K9me/H3K9me2 demethylase activity	KDM7A PHF8	1.99e-04	5	90	2	GO:0140683
GeneOntologyMolecularFunction	MAP kinase kinase kinase activity	BRAF RIPK1 MAP3K12	2.39e-04	27	90	3	GO:0004709
GeneOntologyMolecularFunction	pre-mRNA 3'-splice site binding	U2AF1 U2AF1L4	4.16e-04	7	90	2	GO:0030628
GeneOntologyMolecularFunction	Wnt-protein binding	FZD7 FZD2 RECK	4.79e-04	34	90	3	GO:0017147
GeneOntologyMolecularFunction	transition metal ion binding	USP49 ADAMTS3 ZPR1 RNF144A SEC24B KDM7A PHF8 ZZEF1 MUC2 TRIM49B ADAT2 TOP3A TRIM48 TRIM51G	8.43e-04	1189	90	14	GO:0046914
GeneOntologyMolecularFunction	histone H3K36 demethylase activity	KDM7A PHF8	1.08e-03	11	90	2	GO:0051864
GeneOntologyMolecularFunction	JUN kinase kinase kinase activity	RIPK1 MAP3K12	1.29e-03	12	90	2	GO:0004706
GeneOntologyMolecularFunction	histone H3K9 demethylase activity	KDM7A PHF8	1.76e-03	14	90	2	GO:0032454
GeneOntologyMolecularFunction	calcium ion binding	FBLN1 CELSR1 FBN1 CELSR2 BRAF TKT PCDHB12 MACF1 ZZEF1 ADGRL3	1.99e-03	749	90	10	GO:0005509
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RNF144A LONRF3 UHRF2 ZZEF1 TRIM49B TRIM48 TRIM51G	2.14e-03	398	90	7	GO:0061659
GeneOntologyBiologicalProcess	regulation of establishment of planar polarity involved in neural tube closure	CELSR1 SEC24B FZD2	3.64e-05	15	91	3	GO:0090178
GeneOntologyBiologicalProcess	establishment of planar polarity involved in neural tube closure	CELSR1 SEC24B FZD2	4.46e-05	16	91	3	GO:0090177
GeneOntologyBiologicalProcess	establishment of planar polarity of embryonic epithelium	CELSR1 SEC24B FZD2	6.46e-05	18	91	3	GO:0042249
GeneOntologyBiologicalProcess	regulation of establishment of planar polarity	CELSR1 SEC24B FZD2	7.65e-05	19	91	3	GO:0090175
GeneOntologyBiologicalProcess	Wnt signaling pathway, planar cell polarity pathway	FZD7 CELSR1 CELSR2 FZD2	1.02e-04	55	91	4	GO:0060071
Domain	GPCR_2_secretin-like	FZD7 CELSR1 CELSR2 ADGRL1 ADGRF4 ADGRF3 FZD2 ADGRL3	3.68e-10	60	88	8	IPR000832
Domain	GPCR_2-like	FZD7 CELSR1 CELSR2 ADGRL1 ADGRF4 ADGRF3 FZD2 ADGRL3	3.68e-10	60	88	8	IPR017981
Domain	G_PROTEIN_RECEP_F2_4	FZD7 CELSR1 CELSR2 ADGRL1 ADGRF4 ADGRF3 FZD2 ADGRL3	4.22e-10	61	88	8	PS50261
Domain	GPS	CELSR1 CELSR2 ADGRL1 ADGRF4 ADGRF3 ADGRL3	1.34e-08	35	88	6	PF01825
Domain	GPS	CELSR1 CELSR2 ADGRL1 ADGRF4 ADGRF3 ADGRL3	1.60e-08	36	88	6	PS50221
Domain	GPS	CELSR1 CELSR2 ADGRL1 ADGRF4 ADGRF3 ADGRL3	1.90e-08	37	88	6	IPR000203
Domain	G_PROTEIN_RECEP_F2_1	CELSR1 CELSR2 ADGRL1 ADGRF4 ADGRF3 ADGRL3	3.11e-08	40	88	6	PS00649
Domain	GPCR_2_extracellular_dom	CELSR1 CELSR2 ADGRL1 ADGRF4 ADGRF3 ADGRL3	3.11e-08	40	88	6	IPR001879
Domain	G_PROTEIN_RECEP_F2_3	CELSR1 CELSR2 ADGRL1 ADGRF4 ADGRF3 ADGRL3	3.11e-08	40	88	6	PS50227
Domain	G_PROTEIN_RECEP_F2_2	CELSR1 CELSR2 ADGRL1 ADGRF4 ADGRF3 ADGRL3	1.24e-07	50	88	6	PS00650
Domain	7tm_2	CELSR1 CELSR2 ADGRL1 ADGRF4 ADGRF3 ADGRL3	1.24e-07	50	88	6	PF00002
Domain	GAIN_dom_N	CELSR1 CELSR2 ADGRL1 ADGRL3	1.48e-07	11	88	4	IPR032471
Domain	GAIN	CELSR1 CELSR2 ADGRL1 ADGRL3	1.48e-07	11	88	4	PF16489
Domain	HRM	CELSR1 CELSR2 ADGRL1 ADGRF3 ADGRL3	1.87e-07	28	88	5	PF02793
Domain	GPS	CELSR1 CELSR2 ADGRL1 ADGRF3 ADGRL3	5.17e-07	34	88	5	SM00303
Domain	HormR	CELSR1 CELSR2 ADGRL1 ADGRL3	5.40e-06	25	88	4	SM00008
Domain	Latrophilin	ADGRL1 ADGRL3	6.56e-05	3	88	2	PF02354
Domain	GPCR_2_latrophilin_rcpt_C	ADGRL1 ADGRL3	6.56e-05	3	88	2	IPR003334
Domain	U2AF_small	U2AF1 U2AF1L4	2.17e-04	5	88	2	IPR009145
Domain	GPCR_2_latrophilin	ADGRL1 ADGRL3	2.17e-04	5	88	2	IPR003924
Domain	Lectin_gal-bd_dom	ADGRL1 ADGRL3	2.17e-04	5	88	2	IPR000922
Domain	Gal_Lectin	ADGRL1 ADGRL3	2.17e-04	5	88	2	PF02140
Domain	SUEL_LECTIN	ADGRL1 ADGRL3	2.17e-04	5	88	2	PS50228
Domain	-	USP49 PCGF2 ZNF521 KDM7A PHF8 LONRF3 UHRF2 TRIM49B TRIM48	2.64e-04	449	88	9	3.30.40.10
Domain	Znf_RING/FYVE/PHD	USP49 PCGF2 ZNF521 KDM7A PHF8 LONRF3 UHRF2 TRIM49B TRIM48	3.10e-04	459	88	9	IPR013083
Domain	GPCR_2_secretin-like_CS	ADGRL1 ADGRF3 ADGRL3	5.44e-04	34	88	3	IPR017983
Domain	Frizzled	FZD7 FZD2	1.17e-03	11	88	2	IPR000539
Domain	Frizzled	FZD7 FZD2	1.17e-03	11	88	2	PF01534
Domain	Frizzled	FZD7 FZD2	1.17e-03	11	88	2	SM01330
Domain	ASX_HYDROXYL	FBLN1 CELSR1 FBN1 CELSR2	1.28e-03	100	88	4	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBLN1 CELSR1 FBN1 CELSR2	1.59e-03	106	88	4	IPR000152
Domain	OLF	ADGRL1 ADGRL3	1.66e-03	13	88	2	PS51132
Domain	Olfac-like_dom	ADGRL1 ADGRL3	1.66e-03	13	88	2	IPR003112
Domain	OLF	ADGRL1 ADGRL3	1.66e-03	13	88	2	SM00284
Domain	OLF	ADGRL1 ADGRL3	1.66e-03	13	88	2	PF02191
Domain	Frizzled/SFRP	FZD7 FZD2	2.52e-03	16	88	2	IPR015526
Domain	ZF_RING_1	PCGF2 RNF144A LONRF3 UHRF2 TRIM49B TRIM48	2.53e-03	291	88	6	PS00518
Domain	EGF_CA	FBLN1 CELSR1 FBN1 CELSR2	2.65e-03	122	88	4	SM00179
Domain	EGF-like_Ca-bd_dom	FBLN1 CELSR1 FBN1 CELSR2	2.81e-03	124	88	4	IPR001881
Domain	ZF_RING_2	PCGF2 RNF144A LONRF3 UHRF2 TRIM49B TRIM48	2.85e-03	298	88	6	PS50089
Domain	RING	PCGF2 RNF144A LONRF3 UHRF2 TRIM49B TRIM48	3.19e-03	305	88	6	SM00184
Domain	Pkinase_Tyr	AATK BRAF RIPK1 MAP3K12	3.24e-03	129	88	4	PF07714
Domain	PUA-like_domain	LONRF3 UHRF2	3.56e-03	19	88	2	IPR015947
Domain	FRI	FZD7 FZD2	3.95e-03	20	88	2	SM00063
Domain	zf-C3HC4	PCGF2 RNF144A LONRF3 UHRF2 TRIM48	4.07e-03	223	88	5	PF00097
Domain	Ser-Thr/Tyr_kinase_cat_dom	AATK BRAF RIPK1 MAP3K12	4.12e-03	138	88	4	IPR001245
Domain	-	FZD7 FZD2	4.35e-03	21	88	2	1.10.2000.10
Domain	Znf_RING	PCGF2 RNF144A LONRF3 UHRF2 TRIM49B TRIM48	4.41e-03	326	88	6	IPR001841
Domain	PHD	KDM7A PHF8 UHRF2	5.34e-03	75	88	3	PF00628
Domain	Frizzled_dom	FZD7 FZD2	5.66e-03	24	88	2	IPR020067
Domain	JmjC	KDM7A PHF8	5.66e-03	24	88	2	PF02373
Domain	FZ	FZD7 FZD2	5.66e-03	24	88	2	PS50038
Domain	Fz	FZD7 FZD2	5.66e-03	24	88	2	PF01392
Domain	Znf_PHD-finger	KDM7A PHF8 UHRF2	6.18e-03	79	88	3	IPR019787
Pubmed	International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors.	CELSR1 CELSR2 ADGRL1 ADGRF4 ADGRF3 ADGRL3	3.04e-10	33	92	6	25713288
Pubmed	The adhesion GPCRs CELSR1-3 and LPHN3 engage G proteins via distinct activation mechanisms.	CELSR1 CELSR2 ADGRL3	7.15e-08	4	92	3	37224017
Pubmed	The human and mouse repertoire of the adhesion family of G-protein-coupled receptors.	ADGRL1 ADGRF4 ADGRF3 ADGRL3	1.04e-06	29	92	4	15203201
Pubmed	Role of chromatin remodeling gene Cecr2 in neurulation and inner ear development.	FZD7 CELSR2 FZD2	5.03e-06	13	92	3	21246654
Pubmed	Latrophilin receptors: novel bronchodilator targets in asthma.	ADGRL1 ADGRL3	6.92e-06	2	92	2	27325752
Pubmed	[Clinicopathological features and BRAF V600E and MYD88 L265P mutation status of nodal marginal zone lymphoma].	MYD88 BRAF	6.92e-06	2	92	2	35359040
Pubmed	Drosophila ATP6AP2/VhaPRR functions both as a novel planar cell polarity core protein and a regulator of endosomal trafficking.	CELSR1 CELSR2	6.92e-06	2	92	2	23292348
Pubmed	The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation.	U2AF1 U2AF1L4	6.92e-06	2	92	2	32116123
Pubmed	Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases.	KDM7A PHF8	6.92e-06	2	92	2	20023638
Pubmed	Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.	U2AF1 WDR7 VEZT POLE2 ADAT2 TOP3A	7.42e-06	175	92	6	37866880
Pubmed	Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis.	FZD7 CELSR1 CELSR2 FZD2	7.50e-06	47	92	4	33141892
Pubmed	Amerindian-specific regions under positive selection harbour new lipid variants in Latinos.	CELSR2 ZPR1 DNAH17	9.78e-06	16	92	3	24886709
Pubmed	A family of heptahelical receptors with adhesion-like domains: a marriage between two super families.	ADGRL1 ADGRL3	2.07e-05	3	92	2	10994649
Pubmed	Molecular cloning, differential expression, and chromosomal localization of human frizzled-1, frizzled-2, and frizzled-7.	FZD7 FZD2	2.07e-05	3	92	2	9813155
Pubmed	Reversion-inducing cysteine-rich protein with Kazal motifs and MT1-MMP promote the formation of robust fibrillin fibers.	FBN1 RECK	2.07e-05	3	92	2	32730638
Pubmed	Inhibition of KDM2/7 Promotes Notochordal Differentiation of hiPSCs.	KDM7A PHF8	2.07e-05	3	92	2	39273051
Pubmed	The flamingo-related mouse Celsr family (Celsr1-3) genes exhibit distinct patterns of expression during embryonic development.	CELSR1 CELSR2	2.07e-05	3	92	2	11677057
Pubmed	Characterization of U2AF(6), a splicing factor related to U2AF(35).	U2AF1 U2AF1L4	2.07e-05	3	92	2	11739736
Pubmed	The association of human fibulin-1 with elastic fibers: an immunohistological, ultrastructural, and RNA study.	FBLN1 FBN1	2.07e-05	3	92	2	7534784
Pubmed	The multiple actions of black widow spider toxins and their selective use in neurosecretion studies.	ADGRL1 ADGRL3	2.07e-05	3	92	2	15066411
Pubmed	Frizzled proteins are colonic epithelial receptors for C. difficile toxin B.	FZD7 FZD2	2.07e-05	3	92	2	27680706
Pubmed	alpha-Latrotoxin and its receptors: neurexins and CIRL/latrophilins.	ADGRL1 ADGRL3	2.07e-05	3	92	2	11520923
Pubmed	Wnt signaling in midbrain dopaminergic neuron development and regenerative medicine for Parkinson's disease.	FZD7 CELSR1 CELSR2 FZD2	2.58e-05	64	92	4	24431302
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	BCL11B GATAD2A RAE1 VEZT ASPM CTNNBL1 MACF1 PHF8 LONRF3 RFC3 ANKHD1 ZZEF1	3.84e-05	1116	92	12	31753913
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	IQSEC3 WDR7 CDS2 MACF1 ADGRL1 SEPTIN7 ADGRL3	3.92e-05	347	92	7	17114649
Pubmed	Disruption of Aspm causes microcephaly with abnormal neuronal differentiation.	BCL11B ASPM	4.14e-05	4	92	2	24220505
Pubmed	Frequency of MAP2K1, TP53, and U2AF1 Mutations in BRAF-mutated Langerhans Cell Histiocytosis: Further Characterizing the Genomic Landscape of LCH.	U2AF1 BRAF	4.14e-05	4	92	2	29649018
Pubmed	Ror2 modulates the canonical Wnt signaling in lung epithelial cells through cooperation with Fzd2.	FZD7 FZD2	4.14e-05	4	92	2	18215320
Pubmed	Exogenous IL-33 Restores Dendritic Cell Activation and Maturation in Established Cancer.	MYD88 BRAF	4.14e-05	4	92	2	28011934
Pubmed	Cohesin subunit SMC1 associates with mitotic microtubules at the spindle pole.	RAE1 SMC3	4.14e-05	4	92	2	18832153
Pubmed	Developmental expression profiles of Celsr (Flamingo) genes in the mouse.	CELSR1 CELSR2	4.14e-05	4	92	2	11850187
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	WASHC4 GATAD2A SMC3 PMPCB TKT SEC24B ASPM CTNNBL1 MACF1 PHF8 RFC3 ANKHD1 NMD3	5.67e-05	1353	92	13	29467282
Pubmed	The G protein-coupled receptor repertoires of human and mouse.	ADGRL1 ADGRF4 ADGRF3 ADGRL3	5.92e-05	79	92	4	12679517
Pubmed	Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development.	KDM7A PHF8	6.89e-05	5	92	2	20622853
Pubmed	RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis.	MYD88 RIPK1	6.89e-05	5	92	2	25186904
Pubmed	A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.	CELSR1 PIGT ZBTB7C RIPK1 VEZT CDS2 RFC3 MTERF4 DENND4C	8.68e-05	686	92	9	28380382
Pubmed	Intestinal epithelial cell-derived semaphorin 7A negatively regulates development of colitis via αvβ1 integrin.	MYD88 ITGA1	1.03e-04	6	92	2	22198947
Pubmed	Celsr1 and Celsr2 exhibit distinct adhesive interactions and contributions to planar cell polarity.	CELSR1 CELSR2	1.03e-04	6	92	2	36712970
Pubmed	Direct interaction between NHERF1 and Frizzled regulates β-catenin signaling.	FZD7 FZD2	1.03e-04	6	92	2	20802536
Pubmed	FZD2 regulates limb development by mediating β-catenin-dependent and -independent Wnt signaling pathways.	FZD7 FZD2	1.03e-04	6	92	2	36867021
Pubmed	Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies.	CELSR2 ZPR1	1.03e-04	6	92	2	22003152
Pubmed	Caspase-8 acts as a molecular rheostat to limit RIPK1- and MyD88-mediated dendritic cell activation.	MYD88 RIPK1	1.03e-04	6	92	2	24808358
Pubmed	A RIPK3-caspase 8 complex mediates atypical pro-IL-1β processing.	MYD88 RIPK1	1.03e-04	6	92	2	25567679
Pubmed	A family of MHC class I-like genes located in the vicinity of the mouse leukocyte receptor complex.	PPP5C MICA	1.03e-04	6	92	2	12370446
Pubmed	The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins.	ADGRL1 ADGRL3	1.03e-04	6	92	2	10964907
Pubmed	Early embryonic expression patterns of the mouse Flamingo and Prickle orthologues.	CELSR1 CELSR2	1.44e-04	7	92	2	17937400
Pubmed	NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery.	RAE1 MICA	1.44e-04	7	92	2	25583577
Pubmed	OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice.	MYD88 RIPK1	1.44e-04	7	92	2	34625557
Pubmed	Dectin-1-induced RIPK1 and RIPK3 activation protects host against Candida albicans infection.	MYD88 RIPK1	1.44e-04	7	92	2	30944411
Pubmed	RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis.	MYD88 RIPK1	1.44e-04	7	92	2	24813849
Pubmed	A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.	TIMM10B FBN1 WASHC4 RAE1 RIPK1 PMPCB	1.45e-04	298	92	6	32353859
Pubmed	Large-scale genome-wide association studies in East Asians identify new genetic loci influencing metabolic traits.	CELSR2 ZPR1 ABCB11	1.53e-04	39	92	3	21909109
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	IQSEC3 WASHC4 PHF8 ANKHD1	1.72e-04	104	92	4	10470851
Pubmed	Novel human G protein-coupled receptors with long N-terminals containing GPS domains and Ser/Thr-rich regions.	ADGRF4 ADGRF3	1.92e-04	8	92	2	12435584
Pubmed	EMILIN proteins are novel extracellular constituents of the dentin-pulp complex.	FBLN1 FBN1	1.92e-04	8	92	2	32948785
Pubmed	RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis.	MYD88 RIPK1	1.92e-04	8	92	2	25132550
Pubmed	Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin.	BCL11B ADAMTS3	1.92e-04	8	92	2	28213441
Pubmed	Usp22 deficiency impairs intestinal epithelial lineage specification in vivo.	BCL11B MUC2	1.92e-04	8	92	2	26431380
Pubmed	RIPK1 and RIPK3 Kinases Promote Cell-Death-Independent Inflammation by Toll-like Receptor 4.	MYD88 RIPK1	1.92e-04	8	92	2	27396959
Pubmed	Caspase-8 scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3.	MYD88 RIPK1	1.92e-04	8	92	2	26104484
Pubmed	Sequence requirement and subtype specificity in the high-affinity interaction between human frizzled and dishevelled proteins.	FZD7 FZD2	1.92e-04	8	92	2	19388021
Pubmed	OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis.	MYD88 RIPK1	1.92e-04	8	92	2	32075762
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	U2AF1 PIGT WASHC4 GATAD2A PPP5C SMC3 PMPCB TKT CTNNBL1 RFC3 ANKHD1 NMD3	2.08e-04	1335	92	12	29229926
Pubmed	Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1.	U2AF1 SEC24B U2AF1L4	2.35e-04	45	92	3	33596420
Pubmed	Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study.	CELSR2 ZPR1	2.46e-04	9	92	2	20442857
Pubmed	Redox DAPK1 destabilizes Pellino1 to govern inflammation-coupling tubular damage during septic AKI.	MYD88 RIPK1	2.46e-04	9	92	2	33052227
Pubmed	Microfibril-associated glycoprotein-2 interacts with fibrillin-1 and fibrillin-2 suggesting a role for MAGP-2 in elastic fiber assembly.	FBLN1 FBN1	2.46e-04	9	92	2	12122015
Pubmed	Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.	MYD88 RIPK1	2.46e-04	9	92	2	24799678
Pubmed	A disintegrin and metalloproteinase with thrombospondin motifs 2 cleaves and inactivates Reelin in the postnatal cerebral cortex and hippocampus, but not in the cerebellum.	BCL11B ADAMTS3	2.46e-04	9	92	2	31491533
Pubmed	Dendritic Cell RIPK1 Maintains Immune Homeostasis by Preventing Inflammation and Autoimmunity.	MYD88 RIPK1	2.46e-04	9	92	2	29212904
Pubmed	Direct interaction of Frizzled-1, -2, -4, and -7 with PDZ domains of PSD-95.	FZD7 FZD2	2.46e-04	9	92	2	12067714
Pubmed	Genome-wide association study identifies genes for biomarkers of cardiovascular disease: serum urate and dyslipidemia.	CELSR2 ZPR1	2.46e-04	9	92	2	18179892
Pubmed	Frizzled 2 and frizzled 7 function redundantly in convergent extension and closure of the ventricular septum and palate: evidence for a network of interacting genes.	FZD7 FZD2	2.46e-04	9	92	2	23095888
Pubmed	A novel frizzled gene identified in human esophageal carcinoma mediates APC/beta-catenin signals.	FZD7 FZD2	2.46e-04	9	92	2	9707618
Pubmed	Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice.	U2AF1 ZPR1 U2AF1L4	2.67e-04	47	92	3	29617656
Pubmed	N-methyl-D-aspartate receptors mediate the phosphorylation and desensitization of muscarinic receptors in cerebellar granule neurons.	GRIN2C CHRM3	3.07e-04	10	92	2	19332541
Pubmed	Constitutive interferon signaling maintains critical threshold of MLKL expression to license necroptosis.	MYD88 RIPK1	3.07e-04	10	92	2	29786074
Pubmed	FGF signaling regulates salivary gland branching morphogenesis by modulating cell adhesion.	BRAF ITGA1	3.07e-04	10	92	2	36861436
Pubmed	OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity.	MYD88 RIPK1	3.07e-04	10	92	2	34625556
Pubmed	Expression of Frizzled genes in developing and postnatal hair follicles.	FZD7 FZD2	3.07e-04	10	92	2	15245425
Pubmed	Essential roles of mesenchyme-derived beta-catenin in mouse Müllerian duct morphogenesis.	FZD7 FZD2	3.07e-04	10	92	2	17532316
Pubmed	Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.	ADGRL1 ADGRL3	3.07e-04	10	92	2	38713721
Pubmed	Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells.	FZD7 FZD2	3.75e-04	11	92	2	24860427
Pubmed	A dual role for planar cell polarity genes in ciliated cells.	CELSR1 CELSR2	3.75e-04	11	92	2	25024228
Pubmed	Molecular determinants of WNT9b responsiveness in nephron progenitor cells.	FZD7 FZD2	3.75e-04	11	92	2	30978219
Pubmed	Nervous-tissue-specific elimination of microtubule-actin crosslinking factor 1a results in multiple developmental defects in the mouse brain.	BCL11B MACF1	3.75e-04	11	92	2	20170731
Pubmed	Expression of Frizzled5, Frizzled7, and Frizzled10 during early mouse development and interactions with canonical Wnt signaling.	FZD7 FZD2	3.75e-04	11	92	2	17576136
Pubmed	A20 prevents inflammasome-dependent arthritis by inhibiting macrophage necroptosis through its ZnF7 ubiquitin-binding domain.	MYD88 RIPK1	3.75e-04	11	92	2	31086261
Pubmed	Distinct but redundant expression of the Frizzled Wnt receptor genes at signaling centers of the developing mouse brain.	FZD7 FZD2	3.75e-04	11	92	2	17582687
Pubmed	Lineage-specific biology revealed by a finished genome assembly of the mouse.	MACF1 TRIM49B TRIM48	4.25e-04	55	92	3	19468303
Pubmed	Genome-wide association study identifies three common variants associated with serologic response to vitamin E supplementation in men.	BRAF ZPR1	4.49e-04	12	92	2	22437554
Pubmed	Glucocorticoids cause rapid dissociation of a T-cell-receptor-associated protein complex containing LCK and FYN.	CD3G BRAF	4.49e-04	12	92	2	16888650
Pubmed	Brazilin selectively disrupts proximal IL-1 receptor signaling complex formation by targeting an IKK-upstream signaling components.	MYD88 RIPK1	4.49e-04	12	92	2	24735611
Pubmed	Differential expression of the seven-pass transmembrane cadherin genes Celsr1-3 and distribution of the Celsr2 protein during mouse development.	CELSR1 CELSR2	4.49e-04	12	92	2	11891983
Pubmed	Atypical cadherins Celsr1-3 differentially regulate migration of facial branchiomotor neurons in mice.	CELSR1 CELSR2	4.49e-04	12	92	2	20631168
Pubmed	DNA sequence and analysis of human chromosome 9.	ZER1 BRINP1 UHRF2 OR1L3 RECK DENND4C	4.60e-04	370	92	6	15164053
Pubmed	A mutation in the tuft mouse disrupts TET1 activity and alters the expression of genes that are crucial for neural tube closure.	CELSR1 CELSR2	5.30e-04	13	92	2	26989192
Pubmed	ZBP1 promotes LPS-induced cell death and IL-1β release via RHIM-mediated interactions with RIPK1.	MYD88 RIPK1	5.30e-04	13	92	2	33397971
Pubmed	Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis.	BCL11B ASPM	5.30e-04	13	92	2	38019816
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	MYD88 U2AF1 WASHC4 SMC3 PMPCB CTNNBL1 RFC3 ANKHD1	5.66e-04	704	92	8	29955894
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	4.81e-05	3	73	2	913
GeneFamily	Adhesion G protein-coupled receptors, subfamily C\|CELSR cadherins	CELSR1 CELSR2	4.81e-05	3	73	2	1189
GeneFamily	Adhesion G protein-coupled receptors, subfamily L	ADGRL1 ADGRL3	9.60e-05	4	73	2	918
GeneFamily	Adhesion G protein-coupled receptors, subfamily F	ADGRF4 ADGRF3	1.60e-04	5	73	2	916
GeneFamily	Ring finger proteins	PCGF2 RNF144A LONRF3 UHRF2 TRIM49B TRIM48	8.51e-04	275	73	6	58
GeneFamily	G protein-coupled receptors, Class F frizzled	FZD7 FZD2	8.64e-04	11	73	2	286
GeneFamily	Mitogen-activated protein kinase kinase kinases\|RAF family	BRAF MAP3K12	4.19e-03	24	73	2	654
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM7A PHF8	4.19e-03	24	73	2	485
GeneFamily	PHD finger proteins	KDM7A PHF8 UHRF2	5.77e-03	90	73	3	88
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM49B TRIM48 TRIM51G	6.70e-03	95	73	3	59
Coexpression	GSE7219_WT_VS_NIK_NFKB2_KO_DC_DN	GPD1L POLE2 RNF144A SIDT1 MACF1 ADGRL1 TTC13	1.81e-06	169	89	7	M379
Coexpression	GSE42021_CD24INT_VS_CD24LOW_TREG_THYMUS_DN	MYD88 LIMA1 BCL11B ZBTB7C CDS2 CTNNBL1 GPR87	4.82e-06	196	89	7	M9590
Coexpression	GSE3565_DUSP1_VS_WT_SPLENOCYTES_POST_LPS_INJECTION_UP	POLE2 RNF144A SIDT1 TTC13 ADGRL3 NMD3	2.14e-05	165	89	6	M6332
Coexpression	GSE13547_2H_VS_12_H_ANTI_IGM_STIM_BCELL_DN	PIGT PRELID1 PMPCB TKT POLE2 RFC3	3.95e-05	184	89	6	M2982
Coexpression	GSE36826_WT_VS_IL1R_KO_SKIN_UP	PIGT SIDT1 ZZEF1 FZD2 MAP3K12 TOP3A	5.78e-05	197	89	6	M9537
Coexpression	GSE22886_NAIVE_CD8_TCELL_VS_MONOCYTE_UP	CD3G BCL11B RNF144A SIDT1 MACF1 ADGRL1	6.11e-05	199	89	6	M4494
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_DN	FBN1 AATK RAE1 ASPM RFC3 FZD2	6.29e-05	200	89	6	M9657
Coexpression	GSE45739_NRAS_KO_VS_WT_UNSTIM_CD4_TCELL_UP	U2AF1 GATAD2A POLE2 RNF144A LONRF3 NMD3	6.29e-05	200	89	6	M9877
Coexpression	GSE3982_BASOPHIL_VS_TH2_UP	CELSR1 WASHC4 ZBTB7C CTNNBL1 MACF1 ZZEF1	6.29e-05	200	89	6	M5566
CoexpressionAtlas	gamma delta T cells, Tgd.vg2-.act.Sp, TCRd+ Vg2- CD44+, Spleen, avg-3	CELSR1 CD3G BCL11B RNF144A SIDT1 MACF1 ADGRL1 ITGA1	1.34e-04	377	85	8	GSM476681_500
CoexpressionAtlas	gamma delta T cells, Tgd.vg2+.act.Sp, TCRd+ Vg2+ CD44+, Spleen, avg-3	CELSR1 CD3G BCL11B RNF144A SIDT1 ADGRL1 ITGA1 DENND4C	1.84e-04	395	85	8	GSM476678_500
CoexpressionAtlas	kidney single cell_e11.5_MetanephMesench_StemCellamp_k-means-cluster#2_top-relative-expression-ranked_500	FZD7 ZNF521 RFC3 FZD2	2.00e-04	72	85	4	gudmap_kidney single cell_e11.5_MetanephMesench_Scamp_k2_500
CoexpressionAtlas	alpha beta T cells, T.4.LN.BDC, 4+ 8- BDC+, Lymph Node, avg-3	CD3G BCL11B SIDT1 ADGRL1	2.34e-04	75	85	4	GSM605753_100
CoexpressionAtlas	alpha beta T cells, T.4.PLN.BDC, 4+ 8- BDC+, Lymph Node, avg-3	CD3G BCL11B SIDT1 ADGRL1	2.34e-04	75	85	4	GSM605758_100
CoexpressionAtlas	alpha beta T cells, T.8Mem.Sp.OT1.d45.VSVOva, CD8+ CD45.1+, Spleen, avg-3	CD3G BCL11B SIDT1 ITGA1	2.46e-04	76	85	4	GSM538403_100
CoexpressionAtlas	alpha beta T cells, T.8Eff.Sp.OT1.d8.LisOva, CD8+ CD45.1+, Spleen, avg-3	CD3G BCL11B SIDT1 ITGA1	2.59e-04	77	85	4	GSM605901_100
CoexpressionAtlas	alpha beta T cells, T.8Mem.Sp.OT1.d106.VSVOva, CD8+ CD45.1+, Spleen, avg-2	CD3G BCL11B SIDT1 ITGA1	2.59e-04	77	85	4	GSM538401_100
CoexpressionAtlas	alpha beta T cells, T.8Eff.Sp.OT1.d15.LisOva, CD8+ CD45.1+, Spleen, avg-3	CD3G BCL11B SIDT1 ITGA1	2.59e-04	77	85	4	GSM605894_100
CoexpressionAtlas	alpha beta T cells, T.8Eff.Sp.OT1.d10.LisOva, CD8+ CD45.1+, Spleen, avg-3	CD3G BCL11B SIDT1 ITGA1	2.72e-04	78	85	4	GSM605891_100
CoexpressionAtlas	alpha beta T cells, T.8Mem.Sp.OT1.d45.LisOva, CD8+ CD45.1+, Spleen, avg-2	CD3G BCL11B SIDT1 ITGA1	2.72e-04	78	85	4	GSM605907_100
CoexpressionAtlas	alpha beta T cells, T.4.Pa.BDC, 4+ 8- BDC+, Pancreas, avg-2	CD3G BCL11B SIDT1 ADGRL1	2.72e-04	78	85	4	GSM605756_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#1_top-relative-expression-ranked_1000	BCL11B ADAMTS3 PCDHB12 ZNF521 FZD2 ADGRL3	3.17e-04	229	85	6	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000_k1
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM156 CD3G BCL11B FBN1 SEPTIN7 UHRF2	1.72e-06	175	92	6	06eace2e681980456299167b48bd49bcfea5e940
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM156 CD3G BCL11B MACF1 UHRF2 MTERF4	2.76e-06	190	92	6	91ba66d4b56c59523485b17738e93f14bb00afa4
ToppCell	saliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BCL11B U2AF1L4 ABCB11 TTC13 FZD2	1.99e-05	159	92	5	1dde4d19cc0fde7ebbccb4c31bb845a92206021b
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD3G BCL11B DNAH17 SIDT1 SLC38A11	2.17e-05	162	92	5	b877b232f0a879a9058d81ad4730e7846484b7c3
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD3G BCL11B DNAH17 SIDT1 SLC38A11	2.17e-05	162	92	5	7384a4dd38ed68ca02a72df6deff4d34c9694ce1
ToppCell	moderate-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ADAMTS3 ZNF521 ADGRL1 SLC38A11 GRIN2C	2.44e-05	166	92	5	c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM156 BCL11B BRAF SMC3 TMEM116	2.51e-05	167	92	5	ced6ed9b412739c6ced622523347c10295edbf53
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 CD3G BCL11B SIDT1 RECK	2.74e-05	170	92	5	8e9b5f7bfb61f8d84d0b17fb0c191da4dabad63d
ToppCell	10x3'2.3-week_12-13-Lymphocytic_NK-T_NK-NK_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CD3G BCL11B RIPK1 TMEM116 SEC24B	2.90e-05	172	92	5	a126dacd94939851de1403d30f0b63eaad48bfa1
ToppCell	droplet-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 CD3G BCL11B TMEM116 SIDT1	2.98e-05	173	92	5	da0f1461643294f92e20b5e456a50211a2780a91
ToppCell	facs-Spleen-nan-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CD3G BCL11B SIDT1 RECK	3.32e-05	177	92	5	0d894a14ddbb2734557743e9efdb89cee5c26769
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-mature_NK_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CD3G BCL11B SIDT1 RECK	3.32e-05	177	92	5	52402ff6299210c46fd9dee3cef203c0eda7a98a
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-mature_NK_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD3G BCL11B SIDT1 ITGA1 DENND4C	3.32e-05	177	92	5	6561794ae3b14b5279b249eb5e93b80ef15ed82c
ToppCell	-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	TMEM156 FBLN1 CD3G BCL11B FBN1	3.50e-05	179	92	5	e4224b2e9c4ae7da62cf670adf811f4112c7d060
ToppCell	human_hepatoblastoma-Tumor_cells-T6\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	GPD1L ZBTB7C ARMC3 ZNF521 KDM7A	3.50e-05	179	92	5	14fc8ccb6b215063d747643f47d780d2b237eb67
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AATK CELSR2 POLE2 RASGEF1C ADGRL3	3.60e-05	180	92	5	da723df348d7b8449bb1124f23fe6fa706412adb
ToppCell	droplet-Heart-nan-3m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AATK CELSR2 POLE2 RASGEF1C ADGRL3	3.60e-05	180	92	5	5b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCell	droplet-Heart-nan-3m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AATK CELSR2 POLE2 RASGEF1C ADGRL3	3.60e-05	180	92	5	50758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c13-HAVCR2\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM156 LIMA1 CD3G BCL11B ADAT2	3.79e-05	182	92	5	6c9a48037fa002bc528875538bdaaf15696d68b6
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CELSR2 RASGEF1C TTC13 ADGRL3	3.79e-05	182	92	5	c00e503f442d44fbae73c5e2dc85be69e294e67a
ToppCell	facs-Marrow-T-cells-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPD1L CD3G BCL11B SIDT1 MACF1	3.99e-05	184	92	5	b12fb85a064f715a4f0ada1df8e422c359b573cf
ToppCell	facs-Marrow-T-cells-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPD1L CD3G BCL11B SIDT1 MACF1	4.10e-05	185	92	5	e1fd0a807def8c2127194108b1a30c6de7024292
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN1 FBN1 ZBTB7C ADAMTS3 RNF144A	4.42e-05	188	92	5	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FBLN1 CELSR1 ASPM ADGRF3 RFC3	4.42e-05	188	92	5	0476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM156 CD3G BCL11B ITGA1 UHRF2	4.54e-05	189	92	5	d05e043d0874b8563b9f5514f6c884b35c603e3a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN1 FBN1 ZBTB7C ADAMTS3 RNF144A	4.65e-05	190	92	5	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	P03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADAMTS3 ITGA1 SEPTIN7 RECK ADGRL3	4.65e-05	190	92	5	979b1476fd2692fde977ce56257315fcfc8a01d5
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FBLN1 FBN1 ZBTB7C ADAMTS3 ABCB11	4.77e-05	191	92	5	2c51850f5c559d665b8a27a12b75af9ed58dffe1
ToppCell	Control-Myeloid-Macrophage_Alveolar\|Myeloid / Disease state, Lineage and Cell class	IQSEC3 LIMA1 ZBTB7C CHRM3 DENND4C	4.77e-05	191	92	5	a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCell	NS-moderate-d_07-13-Lymphoid\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM156 CD3G BCL11B ITGA1 SEPTIN7	4.89e-05	192	92	5	bd4059bfc2159f5ed8bbb2a5408b56117ca6f8e1
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM156 CD3G BCL11B ITGA1 UHRF2	5.26e-05	195	92	5	4b9663509cc5e3f409f6d0d37640cb301a827d98
ToppCell	facs-Tongue\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 KLK10 BCL11B CELSR2 GPR87	5.26e-05	195	92	5	77128895db9221a64a171082d468ebcd6380c936
ToppCell	Basal_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	FBLN1 LIMA1 KLK10 CELSR2 GPR87	5.39e-05	196	92	5	3b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM156 BCL11B TTC13 ITGA1 UHRF2	5.39e-05	196	92	5	c9fb81a0578db6d278b8582d7b3add6c407e6dcf
ToppCell	severe_influenza-CD8+_Tem\|World / disease group, cell group and cell class (v2)	LIMA1 CD3G BCL11B MACF1 SEPTIN7	5.39e-05	196	92	5	40fb254abcab2e65affc5d6037e71893a031d264
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	FBLN1 LIMA1 KLK10 CELSR2 GPR87	5.52e-05	197	92	5	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM156 LIMA1 CD3G UHRF2 MTERF4	5.52e-05	197	92	5	7c9df6025b9d168bd6d041c6cff1e87e08b11847
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_TRM/EMRA\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CD3G BCL11B ASPM ITGA1 TRIM49B	5.79e-05	199	92	5	868ff080f72b6274a84e3ae0ddee4a32ed96472a
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	FBLN1 FBN1 ADAMTS3 MACF1 RECK	5.79e-05	199	92	5	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	Sepsis-Int-URO-Lymphocyte-T/NK-CD8+_Tcm\|Int-URO / Disease, condition lineage and cell class	CD3G TMEM116 POLE2 ITGA1 GRIN2C	5.93e-05	200	92	5	9535fd16a962d57e80319bc26093617e04c8b2a8
ToppCell	PND07-28-samps-Lymphocyte-T_cells-T_cells_1\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CD3G BCL11B DNAH17 SIDT1	1.05e-04	118	92	4	461a971f3e8047c727b7c6e00d2d64e97d50c6de
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3\|Hippocampus / BrainAtlas - Mouse McCarroll V32	KLK10 ADGRF4 KDM7A MUC2	1.40e-04	127	92	4	9bc55cb9f4bddb274930784d12a83b9dceb35cb7
ToppCell	Bronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_systemic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FZD7 ARMC3 SLC38A11 ADGRL3	1.72e-04	134	92	4	bffd6ce8998368d4f486b64c220eab3a44ba147b
ToppCell	LPS-IL1RA-Hematopoietic_Mast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IQSEC3 BCL11B SLC38A11 CHRM3	2.14e-04	142	92	4	f7d0d5ca9fc3dd929d4fdd59b71bfa623007e992
ToppCell	LPS-IL1RA-Hematopoietic_Mast-Mast_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	IQSEC3 BCL11B SLC38A11 CHRM3	2.14e-04	142	92	4	2a9a070e7c53ac593d46c6c5f6983f07d4413501
ToppCell	343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|343B / Donor, Lineage, Cell class and subclass (all cells)	U2AF1 CD3G BCL11B TTC13	2.57e-04	149	92	4	2a7f71da51c85e04de2123164914122480e60d66
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LIMA1 CD3G BCL11B ADGRF4	2.64e-04	150	92	4	c922dbb4c9c12ccf08bd5f6168b20606c605d052
ToppCell	368C-Fibroblasts-Fibroblast-F\|368C / Donor, Lineage, Cell class and subclass (all cells)	FBN1 RIPK1 ZNF521 RFC3	3.14e-04	157	92	4	74038192f016f95f80e0189035ee8ccc22ceb1b8
ToppCell	368C-Fibroblasts-Fibroblast-F-\|368C / Donor, Lineage, Cell class and subclass (all cells)	FBN1 RIPK1 ZNF521 RFC3	3.14e-04	157	92	4	982e6ea78c7dabdb7c07c4a5fb2425d5e45b5b94
ToppCell	Control-Epithelial_airway\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CELSR1 ARMC3 GPR87 ADGRF4	3.22e-04	158	92	4	35aee1c3b92169e73569331022833cb44ab7e7e8
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-BM_CD8_+_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD3G BCL11B TMEM116 ITGA1	3.29e-04	159	92	4	e967b557fe6ae4879d36f62c0297cbf6a2ad1ce9
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-mature_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD3G BCL11B TMEM116 ITGA1	3.29e-04	159	92	4	9db971130509c62d439e0cab16588a4d994d7aa0
ToppCell	NS-critical-LOC-Myeloid-Basophil\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FZD7 IQSEC3 ADAMTS3 RNF144A	3.37e-04	160	92	4	8a4746463ca1976f7d6de803496c851249ced797
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	ZBTB7C SLC38A11 ITGA1 ADGRL3	3.37e-04	160	92	4	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	RV-13._Vascular_Smooth_Muscle\|RV / Chamber and Cluster_Paper	ZBTB7C SLC38A11 ITGA1 ADGRL3	3.45e-04	161	92	4	47b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCell	facs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FZD7 LIMA1 GPR87 GRIN2C	3.54e-04	162	92	4	3dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCell	facs-Thymus-Epithelium-3m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FZD7 LIMA1 GPR87 GRIN2C	3.54e-04	162	92	4	0a7138266054ea5954649c8b61ef93905d56b068
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TMEM156 CD3G BCL11B ASPM	3.54e-04	162	92	4	af9999e5fcd28ff1f401d52fd220315752c40027
ToppCell	facs-Thymus-Epithelium-3m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FZD7 LIMA1 GPR87 GRIN2C	3.54e-04	162	92	4	25323785dd33337bcefd05958a4a1a208a9ceb04
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CD3G BCL11B SIDT1	3.62e-04	163	92	4	4af92b211d12c5b88b65bb746242cd702b545bd0
ToppCell	facs-Lung-ENDOMUCIN-18m-Lymphocytic-CD4+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CD3G BCL11B SIDT1	3.62e-04	163	92	4	d24774e0aa612322c22fdb3b314aef275fa01d68
ToppCell	Healthy_Control-Lymphoid-T-innate_T\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	TMEM156 CD3G BCL11B ITGA1	3.79e-04	165	92	4	1ade67229b50fe20eb392262a3e1ee4306b73290
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD3G BCL11B SIDT1 SLC38A11	3.79e-04	165	92	4	475905d608fac628960188ae4a18010b8097417e
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM156 CD3G BCL11B SIDT1	3.79e-04	165	92	4	8dbd03795fff060cd2e4d5d97348f5b63515e030
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM156 CD3G BCL11B SIDT1	3.79e-04	165	92	4	5fc5e34cc805df44c020256729256ef761790152
ToppCell	LV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	ZBTB7C SLC38A11 ITGA1 CHRM3	3.79e-04	165	92	4	f37fd95adc95d7753cf6e55ae819976513c7ec77
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TMEM156 CD3G BCL11B SIDT1	3.79e-04	165	92	4	64c7c45383afde1d050934938705e47aa615755f
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-LTi-like_NCR-_ILC3\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM156 CD3G BCL11B LONRF3	3.88e-04	166	92	4	9fae71b0a42a9b2222453c03e0a1e83f30117ae9
ToppCell	facs-GAT-Fat-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CD3G BCL11B SIDT1	3.88e-04	166	92	4	3695407e4638f3c18fbff63daba52baa9256c429
ToppCell	PND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CELSR1 CD3G BCL11B ASPM	3.97e-04	167	92	4	754e6412d3b9cc0b126e59593df2f5956b4712ef
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD3G BCL11B WDR7 DNAH17	3.97e-04	167	92	4	484de3ca4a905067c18d06995601479eef8fc15e
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 CD3G BCL11B SIDT1	4.06e-04	168	92	4	6c758eb120faf06ff72d157b495e399191c79ec9
ToppCell	PND07-Epithelial-Epithelial_Airway-Basal-Basal-Basal_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KLK10 BCL11B ZBTB7C GPR87	4.06e-04	168	92	4	f150beee37e0252951a88adcd9e3f0a22e5cfdd9
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l9\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 CD3G BCL11B SIDT1	4.06e-04	168	92	4	273168eefe0dae5494ac6ff5306bb307f06dc9c5
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN1 CD3G BCL11B SLC38A11	4.15e-04	169	92	4	3ad534303b4b60a77d171e605a1ba2ef20b5e2a3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FBLN1 CD3G BCL11B SLC38A11	4.15e-04	169	92	4	29dca061864c86218ab73a86cf6e3c522472da47
ToppCell	droplet-Lung-nan-3m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD3G POLE2 SIDT1 ASPM	4.15e-04	169	92	4	df2c9c706bfc9db2bc5726602a49f5f5a94e9481
ToppCell	droplet-Lung-nan-3m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD3G POLE2 SIDT1 ASPM	4.15e-04	169	92	4	f6a6d2f614d60395ad9b867ff1cf59eba72b04ce
ToppCell	facs-SCAT-Fat-18m-Lymphocytic-T_cell\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CD3G BCL11B SIDT1	4.15e-04	169	92	4	700a3a36c379872585204caa6a6cc269b036ae22
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD3G BCL11B POLE2 SIDT1	4.15e-04	169	92	4	1de3ae36d3b60e961bfd9f7bdc37867b82a0417f
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LIMA1 FBN1 MACF1 BRINP1	4.24e-04	170	92	4	7fa022471e14ac8a3bc147c793368a4d56a8e591
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_G2M\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM156 CD3G BCL11B ASPM	4.24e-04	170	92	4	2d5e56eee0c3ce75a9641cc14dee0e0807141c32
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4/8-lo\|Lung / Manually curated celltypes from each tissue	CD3G BCL11B ASPM ITGA1	4.34e-04	171	92	4	dfd4a15ab68ef5a9a1954b1b1540ae04017885a6
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD3G BCL11B SIDT1 CHRM3	4.34e-04	171	92	4	f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	ZBTB7C SLC38A11 ITGA1 CHRM3	4.34e-04	171	92	4	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	facs-GAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CD3G BCL11B SIDT1	4.43e-04	172	92	4	a9f0ccaca0d83bfec79e3251e346a165c34c242b
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADAMTS3 ITGA1 SEPTIN7 RFC3	4.43e-04	172	92	4	03a0aff6b7971093a4347b5ed12546d78374c56f
ToppCell	PND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CD3G U2AF1L4 ADAT2 TOP3A	4.43e-04	172	92	4	dd9ba79e1542fe9fa2c319077d83dd3fc0158f46
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CD3G BCL11B SIDT1 GRIN2C	4.43e-04	172	92	4	33c201aaa98acbf1901b6fa6ce0d3ff8012a4d94
ToppCell	droplet-Lung-1m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD3G BCL11B DNAH17 SIDT1	4.43e-04	172	92	4	5b1f6d4e09e6465acb80b58846ad387e38b155ab
ToppCell	LV-17._Lymphocyte\|World / Chamber and Cluster_Paper	TMEM156 BCL11B SIDT1 SLC38A11	4.53e-04	173	92	4	212f013ff761cbab24a537071739867c08c402a4
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|356C / Donor, Lineage, Cell class and subclass (all cells)	TMEM156 CD3G POLE2 ANKHD1	4.53e-04	173	92	4	e3cb7c8c09f937da6b8d673e9adfec5d94a15548
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ZBTB7C ADAMTS3 ZNF521 SLC38A11	4.53e-04	173	92	4	9a2d42f8d9cb834856522661d524abb91c4637c5
ToppCell	Healthy_Control-Lymphoid-NK-CD8_T\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CD3G BCL11B SIDT1 ITGA1	4.63e-04	174	92	4	5dddb822fa51b4020e4d9318acacd19c726091d6
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CD3G BCL11B TTC13	4.63e-04	174	92	4	1c073177c1753e3b91ef8fd9e95230a1d13c82f3
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CELSR1 CD3G BCL11B SIDT1	4.63e-04	174	92	4	7c8cc5c2872fc7bcca7ebddaf5a6f20e617a2674
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CD3G BCL11B TTC13	4.63e-04	174	92	4	5491ad5c144baf2ef9b1c58eb720c872d14feb15
ToppCell	moderate-Myeloid-Mast_cell\|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ZNF521 ADGRL1 SLC38A11 GRIN2C	4.73e-04	175	92	4	bbd2971bc6d69e507f90a637834d0936c205c590
ToppCell	facs-Skin-nan-24m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 KLK10 BCL11B PRELID1	4.73e-04	175	92	4	21542be95059983d2c8bdf01ec711fdbf1ec1f62
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CD3G BCL11B SIDT1 RECK	4.73e-04	175	92	4	f949613ee45f5d950578c512d197716855118d18
Drug	Forskolin, from Coleus forskohlii; Down 200; 0.5uM; PC3; HT_HG-U133A	FBLN1 PCGF2 PPP5C ADAMTS3 ADGRL1 ZER1 KDM7A	1.08e-05	193	89	7	7059_DN
Drug	Pyrithyldione [77-04-3]; Up 200; 24uM; MCF7; HT_HG-U133A	FBN1 AATK PPP5C CELSR2 DNAH17 ADGRL1 ZER1	1.23e-05	197	89	7	6801_UP
Drug	Methapyrilene hydrochloride [135-23-9]; Up 200; 13.4uM; HL60; HG-U133A	FBLN1 RIPK1 RNF144A MACF1 MTERF4 FZD2 RECK	1.28e-05	198	89	7	1588_UP
Drug	Metoprolol-(+,-) (+)-tartrate salt [56392-17-7]; Up 200; 5.8uM; HL60; HT_HG-U133A	FBLN1 KLK10 ZER1 BRINP1 GRIN2C PHF8 ADGRL3	1.32e-05	199	89	7	2543_UP
Disease	acute respiratory distress syndrome	SMC3 CHRM3	5.26e-05	4	88	2	EFO_1000637
Disease	attention deficit hyperactivity disorder (implicated_via_orthology)	ADGRL1 BRINP1 ADGRL3	7.96e-05	28	88	3	DOID:1094 (implicated_via_orthology)
Disease	Lymphoma	MYD88 BCL11B BRAF	2.34e-04	40	88	3	C0024299
Disease	syndromic X-linked intellectual disability (implicated_via_orthology)	KDM7A PHF8	2.43e-04	8	88	2	DOID:0060309 (implicated_via_orthology)
Disease	response to vitamin	BRAF ZPR1	2.43e-04	8	88	2	GO_0033273
Disease	level of Triacylglycerol (49:2) in blood serum	GATAD2A ZPR1	2.43e-04	8	88	2	OBA_2045162
Disease	cholesterol to total lipids in large VLDL percentage	CELSR2 TMEM116 ZPR1	3.32e-04	45	88	3	EFO_0022236
Disease	level of Triacylglycerol (51:3) in blood serum	GATAD2A ZPR1	3.90e-04	10	88	2	OBA_2045163
Disease	phospholipids in medium LDL measurement	CELSR2 ZPR1 ITGA1	4.28e-04	49	88	3	EFO_0022183
Disease	cholesteryl esters to total lipids in small VLDL percentage	CELSR2 TMEM116 ZPR1	4.28e-04	49	88	3	EFO_0022256
Disease	triglycerides to total lipids in medium LDL percentage	CELSR2 ZPR1 MICA	4.54e-04	50	88	3	EFO_0022334
Disease	cholesteryl esters to total lipids in IDL percentage	ZPR1 MACF1 MICA	4.54e-04	50	88	3	EFO_0022247
Disease	triglycerides to total lipids in large LDL percentage	CELSR2 ZPR1 MICA	4.81e-04	51	88	3	EFO_0022331
Disease	total lipids in medium LDL	CELSR2 ZPR1 ITGA1	5.10e-04	52	88	3	EFO_0022180
Disease	serum metabolite measurement	BCL11B GATAD2A CELSR2 RAE1 RIPK1 TKT ZPR1 DNAH17 TRIM49B TRIM48	5.11e-04	945	88	10	EFO_0005653
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	CELSR2 TMEM116 ZPR1 MACF1 ITGA1	5.44e-04	222	88	5	EFO_0008317, EFO_0020943
Disease	cholesterol to total lipids in large LDL percentage	CELSR2 ZPR1 MICA	6.34e-04	56	88	3	EFO_0022235
Disease	cholesteryl esters to total lipids in large VLDL percentage	CELSR2 TMEM116 ZPR1	6.34e-04	56	88	3	EFO_0022250
Disease	ceramide measurement	ZBTB7C GATAD2A CELSR2 RFC3 NMD3	7.03e-04	235	88	5	EFO_0010222
Disease	cholesterol to total lipids in IDL percentage	ZPR1 MACF1 MICA	7.76e-04	60	88	3	EFO_0022233
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	CELSR2 ADAMTS3	7.82e-04	14	88	2	EFO_0004611, EFO_0008589
Disease	triglycerides to total lipids in IDL percentage	CELSR2 ZPR1 MICA	8.94e-04	63	88	3	EFO_0022329
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	GATAD2A CELSR2 ZPR1 MACF1	9.23e-04	144	88	4	EFO_0004611, EFO_0020943
Disease	total lipids in very large HDL measurement	PIGT CELSR2 ZPR1	1.02e-03	66	88	3	EFO_0022312
Disease	level of triacylglycerol (56:6) in blood serum	GATAD2A ZPR1	1.03e-03	16	88	2	OBA_2020007
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	CELSR2 ZPR1 MACF1 MICA	1.07e-03	150	88	4	EFO_0004611, EFO_0020947
Disease	partial epilepsy	FZD7 ADGRL3	1.16e-03	17	88	2	EFO_0004263
Disease	cholesterol in very large HDL measurement	PIGT CELSR2 ZPR1	1.16e-03	69	88	3	EFO_0022229
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	CELSR2 TMEM116 ZPR1 MACF1 ITGA1	1.18e-03	264	88	5	EFO_0008317, EFO_0020944
Disease	very low density lipoprotein cholesterol measurement, esterified cholesterol measurement	CELSR2 ZPR1	1.30e-03	18	88	2	EFO_0008317, EFO_0008589
Disease	non-high density lipoprotein cholesterol measurement	FBLN1 PPP5C CELSR2 ADAMTS3 ZPR1 ABCB11 ITGA1 DENND4C	1.31e-03	713	88	8	EFO_0005689
Disease	free cholesterol to total lipids in large LDL percentage	CELSR2 ZPR1 MACF1	1.43e-03	74	88	3	EFO_0022280
Disease	sodium-coupled monocarboxylate transporter 1 measurement	CELSR2 ZPR1	1.45e-03	19	88	2	EFO_0802076
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	GATAD2A CELSR2 ZPR1 MACF1 MICA	1.81e-03	291	88	5	EFO_0008317, EFO_0020946
Disease	progranulin measurement	CELSR2 ADGRL1	1.95e-03	22	88	2	EFO_0004625
Disease	colorectal cancer	LIMA1 BCL11B FBN1 MACF1 MICA RFC3 CHRM3	2.21e-03	604	88	7	MONDO_0005575
Disease	large artery stroke, coronary artery disease	CELSR2 ZPR1	2.52e-03	25	88	2	EFO_0001645, EFO_0005524
Disease	urate measurement, bone density	TMEM156 FBLN1 BCL11B WDR7 PMPCB GRIN2C CHRM3	2.53e-03	619	88	7	EFO_0003923, EFO_0004531
Disease	revision of total knee arthroplasty	RIPK1 ADGRL3	2.73e-03	26	88	2	EFO_0020972
Disease	cholesteryl ester 14:0 measurement	ZPR1 SLC38A11	2.94e-03	27	88	2	EFO_0010340

Protein segments in the cluster

Peptide	Gene	Start	Entry
RCSTEVPLMCVNYDQ	BRAF	271	P15056
LAVQRCPMADTTYAC	ADGRF3	391	Q8IZF5
PLQVYYRMCQNCIEL	CD3G	96	P09693
YVTVEPCIMCAAALR	ADAT2	101	Q7Z6V5
ICYIMAEICNANVPQ	CTNNBL1	496	Q8WYA6
CNCPITDIQIMEYTL	BRINP1	276	O60477
CDADPFQMENVQCYL	ADGRL1	71	O94910
PYNIMVLVNTFCDSC	CHRM3	506	P20309
RKNCPFDYACITDMV	ADGRF4	136	Q8IZF3
CDSDPAQMENIRCYL	ADGRL3	66	Q9HAR2
IVPISCVICNDIMAY	CDS2	226	O95674
QLIQRFYDPCEGMVT	ABCB11	466	O95342
NPCRIQYCTQEITVF	POLE2	401	P56282
MECIYNLVQDFQCRA	ARMC3	171	Q5W041
PCENYMKCVSVLRFD	CELSR1	1311	Q9NYQ6
PCENYMRCVSVLRFD	CELSR2	1236	Q9HCU4
CNRSIPCMEVIRYAV	ASPM	3306	Q8IZT6
ERCYCADVIYPMAVV	RAE1	171	P78406
CEYNPVEVSMLTCLA	RECK	326	O95980
RICQGEEQRFTCYME	MICA	271	Q29983
AATVLSREPYMCAQC	GATAD2A	406	Q86YP4
TPICEDIGRQMLCYN	PMPCB	416	O75439
VLPAVMSCDRYVAVC	OR2G2	116	Q8NGZ5
VCRQPYDVNRFMIEC	KDM7A	41	Q6ZMT4
ARETCVECQKTVYPM	LIMA1	386	Q9UHB6
CCVASLVQVMLDPYF	MTMR10	411	Q9NXD2
CYESRPVQEMLSCLQ	GPD1L	331	Q8N335
YELERCLLMPQCNAF	KIAA2026	326	Q5HYC2
IPMAFCLNYEINVQC	MUC2	1861	Q02817
FLCSMYAPVCTVLEQ	FZD2	91	Q14332
CYCPSDIQFVQEMIR	MYD88	166	Q99836
RYSVVMNGPVCVCLV	OR13H1	131	Q8NG92
FEYQMSLEPIKQTCC	ITGA1	536	P56199
EAFSQRYCMCNPEVV	IQSEC3	756	Q9UPP2
NVCLDPIIYFFMCRS	GPR87	306	Q9BY21
PVQCESDVIMYIQEC	MACF1	466	Q9UPN3
CGSNEPCVLYFQVLM	PCDHB12	96	Q9Y5F1
EYPVEQMTTIAQCQC	RNF144A	26	P50876
YLETNKYCPMCDVQV	PCGF2	46	P35227
MCVDVNECQRYPGRL	FBLN1	396	P23142
FLCSMYAPVCTVLDQ	FZD7	101	O75084
IFCQMEVLARYCSIP	ADAMTS3	1026	O15072
KEVYRCDICQMPFSV	BCL11B	851	Q9C0K0
PYVVVAFQECERMNI	DNAH17	4226	Q9UFH2
EGYCFTEVLQNMCQI	FBN1	2336	P35555
DPLDEVCYRVVMQLC	DENND4C	816	Q5VZ89
TQAPCYCILMEFCAQ	MAP3K12	181	Q12852
DKYCQMPSFEEICVF	MS4A14	136	Q96JA4
CDLCYTPMIVAADFV	DUS4L	51	O95620
CNLCYRVNDVPEEFM	SEC24B	626	O95487
YPMECFVTREVIANV	SLC38A11	256	Q08AI6
ALLMCEACRVQQYPF	RFC3	226	P40938
ICNPFHYVTVMNRRC	OR1L3	126	Q8NH93
YVAICCPLNYEVIMN	OR14A2	121	Q96R54
EPMYCFLCVLAAVDI	OR52I1	61	Q8NGK6
YNRMTELCFQRCVPS	TIMM10B	21	Q9Y5J6
QRELTCPICMNYFID	TRIM48	26	Q8IWZ4
CPICMNYFIDPVTID	TRIM48	31	Q8IWZ4
VMNNFECEPAFYTCV	SMC3	536	Q9UQE7
QCAEVTPYLLVMEFC	AATK	191	Q6ZMQ8
YCCPEIFTMRQQDIN	MTERF4	181	Q7Z6M4
RCVTVFSAPNYCDQM	PPP5C	441	P53041
MVVEERCVYCVNSDN	PRELID1	106	Q9Y255
EPYENAICEQQLIMC	RIPK1	226	Q13546
VNQFPSDIECMRYIA	ANKHD1	1381	Q8IWZ3
MYNLIILVCRACFPD	CNGA4	46	Q8IV77
INYTCRIMEYPNDCI	TMEM156	181	Q8N614
FMCVCCQELVYQPVT	UHRF2	731	Q96PU4
EQQPTEIESLCMNCY	ZPR1	41	O75312
RCLQLEPYNEVCQYM	TTC13	376	Q8NBP0
MESYQEVTVQRNCCL	ZER1	446	Q7Z7L7
PDRFIECYIAEQNMV	TKT	356	P29401
DFSMPYNVICLTCTV	PIGT	521	Q969N2
RQMPDNRVQCCLYFI	SEPTIN7	151	Q16181
NRLCYLVATEICMPA	RASGEF1C	256	Q8N431
RRAAMVFYTDCIQQC	SIDT1	661	Q9NXL6
AMPAIVYQCNFCSEV	ZNF521	471	Q96K83
VVFDQVLTMEPYCCR	USP49	571	Q70CQ1
SPLVIDYTCRVCQMA	TMEM116	11	Q8NCL8
PVTDFREACCRQYEM	U2AF1	146	Q01081
PVTDFRESCCRQYEM	U2AF1L4	146	Q8WU68
CLVLYQLCVEDPMAT	TOP3A	296	Q13472
PICMNYFIDPVTIDC	TRIM51G	16	A0A3B3IT33
PYMCTICEVRFTRQD	ZBTB7C	391	A1YPR0
ELSCFVTRCYEVVMN	WASHC4	146	Q2M389
FPQVLCVGTRCVYMD	ZZEF1	2251	O43149
CRLPYDVTRFMIECD	PHF8	46	Q9UPP1
PICMNYFIDPVTIDC	TRIM49B	16	A6NDI0
VFPQGAEERMCYQCE	VEZT	681	Q9HBM0
LQECFPAICRFYMVS	WDR7	1346	Q9Y4E6
CEVFYPGVVTNNMIC	KLK10	201	O43240
ECALCMRLFYEPVTT	LONRF3	466	Q496Y0
QKMVEFLQCTVPCRY	NMD3	206	Q96D46
QSMCLPIYREACQEG	GRIN2C	1121	Q14957