Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

HSPG2 PCLO NOTCH2NLA DLL1 NOTCH2NLC SVEP1 TGM2 THBS1 SCUBE1 FBN2 NOTCH2NLB SPOCK3 SCUBE3 HABP2 LTBP3 LTBP4 FBN3 NOTCH1 NOTCH2 NOTCH4 CRB2

2.01e-117499221GO:0005509
GeneOntologyMolecularFunctionextracellular matrix structural constituent

HSPG2 VWF LAMA1 LAMA2 LAMB2 SSPOP THBS1 FBN2 MEGF9 LTBP4 FBN3

1.06e-091889211GO:0005201
GeneOntologyMolecularFunctionNotch binding

NOTCH2NLA DLL1 NOTCH2NLB NOTCH1 MEGF10 NOTCH4

2.22e-0927926GO:0005112
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

9.40e-075923GO:0030156
GeneOntologyMolecularFunctioncollagen V binding

HSPG2 THBS1

2.08e-045922GO:0070052
GeneOntologyMolecularFunctiontransforming growth factor beta binding

THBS1 LTBP3 LTBP4

2.28e-0426923GO:0050431
GeneOntologyMolecularFunctiongrowth factor binding

ERBB3 THBS1 IGF2R LTBP3 LTBP4

7.77e-04156925GO:0019838
GeneOntologyMolecularFunctionstructural molecule activity

HSPG2 VWF PCLO LAMA1 LAMA2 LAMB2 SSPOP THBS1 FBN2 MEGF9 LTBP4 FBN3

7.86e-048919212GO:0005198
GeneOntologyMolecularFunctioncytokine binding

TNFRSF14 THBS1 SCUBE3 LTBP3 LTBP4

8.00e-04157925GO:0019955
GeneOntologyMolecularFunctionintegrin binding

VWF LAMB2 SVEP1 THBS1 LTBP4

1.30e-03175925GO:0005178
GeneOntologyMolecularFunctionglycosaminoglycan binding

THBS1 SPOCK3 TENM1 HABP2 LTBP4 RSPO1

1.50e-03268926GO:0005539
GeneOntologyBiologicalProcessregulation of muscle cell differentiation

LAMA1 LAMA2 LAMB2 DLL1 NOTCH1 MEGF10 NOTCH2 NOTCH4

2.57e-06199908GO:0051147
GeneOntologyBiologicalProcesspositive regulation of Notch signaling pathway

NOTCH2NLA DLL1 NOTCH2NLC NOTCH2NLB NOTCH1

3.44e-0653905GO:0045747
GeneOntologyBiologicalProcessmuscle structure development

ERBB3 TCF7L2 LAMA1 LAMA2 LAMB2 DLL1 GSC HIVEP3 KMT5B DYRK1B PLG NOTCH1 MEGF10 NOTCH2 NOTCH4

4.25e-068589015GO:0061061
GeneOntologyBiologicalProcesspositive regulation of muscle cell differentiation

LAMA1 LAMA2 LAMB2 NOTCH1 NOTCH2 NOTCH4

7.01e-06106906GO:0051149
GeneOntologyBiologicalProcessnegative regulation of cell-cell adhesion mediated by cadherin

PLG NOTCH1 NOTCH4

9.43e-0610903GO:2000048
GeneOntologyBiologicalProcessregulation of Notch signaling pathway

NOTCH2NLA DLL1 NOTCH2NLC NOTCH2NLB NOTCH1 NOTCH4

1.07e-05114906GO:0008593
GeneOntologyBiologicalProcessregulation of cell adhesion

HSPG2 ERBB3 DUSP3 TNFRSF14 LAMA1 LAMA2 LAMB2 DLL1 TGM2 THBS1 PKD1 PLG NOTCH1 MEGF10 NOTCH4

1.07e-059279015GO:0030155
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

TCF7L2 HTRA3 DLL1 THBS1 FBN2 SCUBE3 LTBP4 NOTCH1 NOTCH2 CRB2

1.25e-054129010GO:0090287
GeneOntologyBiologicalProcessregulation of basement membrane organization

LAMA1 LAMA2 LAMB2

1.29e-0511903GO:0110011
GeneOntologyBiologicalProcessneuromuscular synaptic transmission

CACNA1A RIMBP3 RIMBP3C RIMBP3B

1.79e-0536904GO:0007274
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

TCF7L2 HTRA3 THBS1 FBN2 SCUBE3 LTBP4 NOTCH1 NOTCH2 CRB2

2.08e-05347909GO:0090092
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

TCF7L2 HTRA3 SCUBE3 NOTCH1 NOTCH2 CRB2

2.35e-05131906GO:0030510
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

TCF7L2 HTRA3 THBS1 FBN2 SCUBE3 LTBP3 LTBP4 NOTCH1 NOTCH2 CRB2

2.42e-054459010GO:0141091
GeneOntologyBiologicalProcesspositive regulation of integrin-mediated signaling pathway

LAMA1 LAMA2 LAMB2

2.82e-0514903GO:2001046
GeneOntologyBiologicalProcessleft/right axis specification

DLL1 NOTCH1 NOTCH2

2.82e-0514903GO:0070986
GeneOntologyBiologicalProcessanimal organ morphogenesis

HSPG2 TCF7L2 LAMA1 LAMA2 LAMB2 DLL1 GSC TGM2 THBS1 FBN2 MEGF9 GLI1 PKD1 LTBP3 NOTCH1 NOTCH2 CRB2

3.01e-0512699017GO:0009887
GeneOntologyBiologicalProcessgland development

TCF7L2 VWF LAMA1 TGM2 IGF2R PYGO2 GLI1 PKD1 NOTCH1 NOTCH2 NOTCH4

3.10e-055589011GO:0048732
GeneOntologyBiologicalProcesspositive regulation of BMP signaling pathway

SCUBE3 NOTCH1 NOTCH2 CRB2

3.34e-0542904GO:0030513
GeneOntologyBiologicalProcessaxon guidance

HSPG2 LAMA1 LAMA2 LAMB2 MEGF9 SEMA4A NOTCH1 NOTCH2

3.50e-05285908GO:0007411
GeneOntologyBiologicalProcessmesenchyme development

ERBB3 TCF7L2 GSC THBS1 USF3 SEMA4A NOTCH1 NOTCH4 CRB2

3.58e-05372909GO:0060485
GeneOntologyBiologicalProcessneuron projection guidance

HSPG2 LAMA1 LAMA2 LAMB2 MEGF9 SEMA4A NOTCH1 NOTCH2

3.59e-05286908GO:0097485
GeneOntologyBiologicalProcessNotch signaling pathway

NOTCH2NLA DLL1 NOTCH2NLC NOTCH2NLB NOTCH1 NOTCH2 NOTCH4

3.75e-05210907GO:0007219
GeneOntologyBiologicalProcesscirculatory system development

HSPG2 ERBB3 TCF7L2 LAMA1 ADGRB2 DLL1 SVEP1 TGM2 THBS1 SCUBE1 GLI1 PKD1 SEMA4A PLG NOTCH1 NOTCH2 NOTCH4 CRB2

4.31e-0514429018GO:0072359
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

TCF7L2 HTRA3 THBS1 FBN2 SCUBE3 LTBP3 LTBP4 NOTCH1 NOTCH2 CRB2

4.76e-054829010GO:0007178
GeneOntologyBiologicalProcesscellular response to tumor cell

NOTCH1 NOTCH2

5.63e-053902GO:0071228
GeneOntologyBiologicalProcesscerebellar molecular layer development

CACNA1A DLL1

5.63e-053902GO:0021679
GeneOntologyBiologicalProcessregulation of embryonic development

LAMA1 LAMA2 DLL1 NOTCH1 CRB2

7.32e-0599905GO:0045995
GeneOntologyBiologicalProcessvasculature development

HSPG2 TCF7L2 LAMA1 ADGRB2 DLL1 SVEP1 TGM2 THBS1 PKD1 SEMA4A PLG NOTCH1 NOTCH2 NOTCH4

7.50e-059699014GO:0001944
GeneOntologyBiologicalProcessbrain development

B4GALT2 CACNA1A HSPG2 TCF7L2 NOTCH2NLA DLL1 NOTCH2NLC GSC PYGO2 NOTCH2NLB GLI1 SOX14 NOTCH1

8.75e-058599013GO:0007420
GeneOntologyBiologicalProcessregulation of cell-cell adhesion mediated by cadherin

PLG NOTCH1 NOTCH4

1.01e-0421903GO:2000047
GeneOntologyBiologicalProcessregulation of muscle tissue development

ERBB3 TCF7L2 DLL1 MEGF10

1.12e-0457904GO:1901861
GeneOntologyBiologicalProcesspositive regulation of aorta morphogenesis

NOTCH1 NOTCH4

1.12e-044902GO:1903849
GeneOntologyBiologicalProcessmuscle organ development

ERBB3 TCF7L2 LAMA2 DLL1 GSC HIVEP3 KMT5B NOTCH1 MEGF10

1.21e-04436909GO:0007517
GeneOntologyBiologicalProcessregulation of integrin-mediated signaling pathway

LAMA1 LAMA2 LAMB2

1.34e-0423903GO:2001044
GeneOntologyBiologicalProcesspositive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

THBS1 SCUBE3 NOTCH1 NOTCH2 CRB2

1.49e-04115905GO:0090100
GeneOntologyBiologicalProcessembryonic organ morphogenesis

HSPG2 TCF7L2 DLL1 GSC GLI1 NOTCH1 NOTCH2 CRB2

1.50e-04351908GO:0048562
GeneOntologyBiologicalProcessembryonic organ development

HSPG2 TCF7L2 DLL1 GSC GLI1 PKD1 PLG NOTCH1 NOTCH2 CRB2

1.66e-045619010GO:0048568
GeneOntologyBiologicalProcesshead development

B4GALT2 CACNA1A HSPG2 TCF7L2 NOTCH2NLA DLL1 NOTCH2NLC GSC PYGO2 NOTCH2NLB GLI1 SOX14 NOTCH1

1.71e-049199013GO:0060322
GeneOntologyBiologicalProcessenzyme-linked receptor protein signaling pathway

ERBB3 TCF7L2 DUSP3 HTRA3 DLL1 SVEP1 THBS1 FBN2 IGF2R SCUBE3 LTBP3 LTBP4 NOTCH1 NOTCH2 CRB2

1.78e-0411869015GO:0007167
GeneOntologyBiologicalProcessnegative regulation of inner ear receptor cell differentiation

DLL1 NOTCH1

1.87e-045902GO:2000981
GeneOntologyBiologicalProcesscompartment pattern specification

DLL1 NOTCH1

1.87e-045902GO:0007386
GeneOntologyBiologicalProcessnegative regulation of inner ear auditory receptor cell differentiation

DLL1 NOTCH1

1.87e-045902GO:0045608
GeneOntologyBiologicalProcessnegative regulation of mechanoreceptor differentiation

DLL1 NOTCH1

1.87e-045902GO:0045632
GeneOntologyBiologicalProcessblood vessel development

HSPG2 TCF7L2 LAMA1 ADGRB2 DLL1 TGM2 THBS1 PKD1 SEMA4A PLG NOTCH1 NOTCH2 NOTCH4

1.90e-049299013GO:0001568
GeneOntologyBiologicalProcesscentral nervous system development

B4GALT2 CACNA1A HSPG2 TCF7L2 NOTCH2NLA LAMB2 DLL1 NOTCH2NLC GSC PYGO2 NOTCH2NLB GLI1 BRINP2 SOX14 NOTCH1

1.97e-0411979015GO:0007417
GeneOntologyBiologicalProcessBMP signaling pathway

TCF7L2 HTRA3 SCUBE3 NOTCH1 NOTCH2 CRB2

2.25e-04197906GO:0030509
GeneOntologyBiologicalProcessnegative regulation of cell adhesion

HSPG2 ERBB3 DUSP3 TNFRSF14 THBS1 PLG NOTCH1 NOTCH4

2.35e-04375908GO:0007162
GeneOntologyBiologicalProcesspositive regulation of smooth muscle cell differentiation

NOTCH1 NOTCH2 NOTCH4

2.43e-0428903GO:0051152
GeneOntologyBiologicalProcessliver development

VWF IGF2R GLI1 PKD1 NOTCH1 NOTCH2

2.58e-04202906GO:0001889
GeneOntologyBiologicalProcesscerebellar cortex development

B4GALT2 CACNA1A DLL1 GLI1

2.63e-0471904GO:0021695
GeneOntologyBiologicalProcessepithelial to mesenchymal transition

TCF7L2 GSC USF3 NOTCH1 NOTCH4 CRB2

2.64e-04203906GO:0001837
GeneOntologyBiologicalProcesshepaticobiliary system development

VWF IGF2R GLI1 PKD1 NOTCH1 NOTCH2

2.79e-04205906GO:0061008
GeneOntologyBiologicalProcessinner ear receptor cell fate commitment

DLL1 NOTCH1

2.79e-046902GO:0060120
GeneOntologyBiologicalProcessregulation of aorta morphogenesis

NOTCH1 NOTCH4

2.79e-046902GO:1903847
GeneOntologyBiologicalProcessauditory receptor cell fate commitment

DLL1 NOTCH1

2.79e-046902GO:0009912
GeneOntologyBiologicalProcessinhibition of neuroepithelial cell differentiation

DLL1 NOTCH1

2.79e-046902GO:0002085
GeneOntologyBiologicalProcessarterial endothelial cell differentiation

DLL1 NOTCH1

2.79e-046902GO:0060842
GeneOntologyBiologicalProcessmesenchymal cell differentiation

TCF7L2 GSC USF3 SEMA4A NOTCH1 NOTCH4 CRB2

3.16e-04296907GO:0048762
GeneOntologyBiologicalProcesscellular response to growth factor stimulus

TCF7L2 DUSP3 HTRA3 DLL1 THBS1 FBN2 SCUBE3 LTBP3 LTBP4 NOTCH1 NOTCH2 CRB2

3.17e-048509012GO:0071363
GeneOntologyBiologicalProcessmyoblast differentiation

TCF7L2 DLL1 PLG NOTCH1 MEGF10

3.25e-04136905GO:0045445
GeneOntologyBiologicalProcesspositive regulation of hemostasis

VWF THBS1 PLG

3.31e-0431903GO:1900048
GeneOntologyBiologicalProcesspositive regulation of blood coagulation

VWF THBS1 PLG

3.31e-0431903GO:0030194
GeneOntologyBiologicalProcesstube development

HSPG2 TCF7L2 LAMA1 ADGRB2 DLL1 GSC TGM2 THBS1 GLI1 PKD1 LTBP3 SEMA4A PLG NOTCH1 NOTCH2 NOTCH4

3.40e-0414029016GO:0035295
GeneOntologyBiologicalProcesstube morphogenesis

HSPG2 TCF7L2 LAMA1 ADGRB2 DLL1 TGM2 THBS1 GLI1 PKD1 SEMA4A PLG NOTCH1 NOTCH2 NOTCH4

3.54e-0411259014GO:0035239
GeneOntologyBiologicalProcessresponse to BMP

TCF7L2 HTRA3 SCUBE3 NOTCH1 NOTCH2 CRB2

3.60e-04215906GO:0071772
GeneOntologyBiologicalProcesscellular response to BMP stimulus

TCF7L2 HTRA3 SCUBE3 NOTCH1 NOTCH2 CRB2

3.60e-04215906GO:0071773
GeneOntologyBiologicalProcessnegative regulation of endothelial cell chemotaxis

THBS1 NOTCH1

3.90e-047902GO:2001027
GeneOntologyBiologicalProcesspositive regulation of transcription of Notch receptor target

NOTCH1 NOTCH4

3.90e-047902GO:0007221
GeneOntologyBiologicalProcessregulation of somitogenesis

DLL1 NOTCH1

3.90e-047902GO:0014807
GeneOntologyBiologicalProcessanimal organ regeneration

HSPG2 IGF2R GLI1 NOTCH1

3.97e-0479904GO:0031100
GeneOntologyBiologicalProcessregulation of skeletal muscle tissue development

TCF7L2 DLL1 MEGF10

3.99e-0433903GO:0048641
GeneOntologyBiologicalProcessnegative regulation of stem cell differentiation

TRIM6 BBS12 NOTCH1

3.99e-0433903GO:2000737
GeneOntologyBiologicalProcesspositive regulation of cell differentiation

PDE3A TCF7L2 LAMA1 LAMA2 LAMB2 TGM2 FBN2 BRINP2 SCUBE3 LTBP3 NOTCH1 NOTCH2 NOTCH4 CRB2

4.08e-0411419014GO:0045597
GeneOntologyBiologicalProcesscell-substrate adhesion

VWF DUSP3 LAMB2 SVEP1 THBS1 PKD1 PLG NOTCH1

4.26e-04410908GO:0031589
GeneOntologyBiologicalProcesspositive regulation of coagulation

VWF THBS1 PLG

4.36e-0434903GO:0050820
GeneOntologyBiologicalProcessresponse to growth factor

TCF7L2 DUSP3 HTRA3 DLL1 THBS1 FBN2 SCUBE3 LTBP3 LTBP4 NOTCH1 NOTCH2 CRB2

4.46e-048839012GO:0070848
GeneOntologyBiologicalProcessregulation of angiogenesis

HSPG2 ADGRB2 DLL1 TGM2 THBS1 SEMA4A PLG NOTCH4

5.00e-04420908GO:0045765
GeneOntologyBiologicalProcessregulation of extracellular matrix organization

LAMA1 LAMA2 LAMB2 NOTCH1

5.01e-0484904GO:1903053
GeneOntologyBiologicalProcessglial cell differentiation

ERBB3 TCF7L2 LAMA2 LAMB2 DLL1 NOTCH1 NOTCH2

5.13e-04321907GO:0010001
GeneOntologyBiologicalProcessmuscle cell differentiation

LAMA1 LAMA2 LAMB2 DLL1 DYRK1B NOTCH1 MEGF10 NOTCH2 NOTCH4

5.16e-04531909GO:0042692
GeneOntologyBiologicalProcessregulation of vasculature development

HSPG2 ADGRB2 DLL1 TGM2 THBS1 SEMA4A PLG NOTCH4

5.83e-04430908GO:1901342
GeneOntologyBiologicalProcessresponse to wounding

ERBB3 VWF LAMB2 SVEP1 THBS1 SCUBE1 GLI1 PLG NOTCH2 NOTCH4

5.94e-046599010GO:0009611
GeneOntologyBiologicalProcessanatomical structure formation involved in morphogenesis

CACNA1A HSPG2 ADGRB2 DLL1 GSC TGM2 THBS1 FBN2 DYRK1B PKD1 SEMA4A PLG NOTCH1 NOTCH2 NOTCH4 CRB2

6.31e-0414839016GO:0048646
GeneOntologyBiologicalProcesscerebellar Purkinje cell layer development

B4GALT2 CACNA1A DLL1

6.55e-0439903GO:0021680
GeneOntologyBiologicalProcessatrioventricular node development

NOTCH1 NOTCH2

6.64e-049902GO:0003162
GeneOntologyBiologicalProcesspositive regulation of artery morphogenesis

NOTCH1 NOTCH4

6.64e-049902GO:1905653
GeneOntologyBiologicalProcessmuscle tissue development

HSPG2 ERBB3 TCF7L2 DLL1 HIVEP3 GLI1 NOTCH1 MEGF10 NOTCH2

7.35e-04558909GO:0060537
GeneOntologyBiologicalProcessaxonogenesis

CACNA1A HSPG2 LAMA1 LAMA2 LAMB2 MEGF9 SEMA4A NOTCH1 NOTCH2

8.13e-04566909GO:0007409
GeneOntologyBiologicalProcessmarginal zone B cell differentiation

DLL1 NOTCH2

8.28e-0410902GO:0002315
GeneOntologyBiologicalProcessglomerular epithelial cell development

LAMB2 NOTCH2

8.28e-0410902GO:0072310
GeneOntologyBiologicalProcesspodocyte development

LAMB2 NOTCH2

8.28e-0410902GO:0072015
GeneOntologyBiologicalProcessproximal tubule development

DLL1 NOTCH2

8.28e-0410902GO:0072014
GeneOntologyBiologicalProcessregeneration

HSPG2 LAMB2 IGF2R GLI1 PLG NOTCH1

8.29e-04252906GO:0031099
GeneOntologyBiologicalProcessblood vessel morphogenesis

HSPG2 LAMA1 ADGRB2 DLL1 TGM2 THBS1 SEMA4A PLG NOTCH1 NOTCH2 NOTCH4

8.46e-048179011GO:0048514
GeneOntologyBiologicalProcessbasement membrane organization

LAMA1 LAMA2 LAMB2

8.74e-0443903GO:0071711
GeneOntologyBiologicalProcessperipheral nervous system development

ERBB3 ADGRB2 LAMA2 LAMB2

8.96e-0498904GO:0007422
GeneOntologyBiologicalProcessregulation of stem cell differentiation

TRIM6 LTBP3 BBS12 NOTCH1

9.30e-0499904GO:2000736
GeneOntologyBiologicalProcessplacenta blood vessel development

PKD1 PLG NOTCH2

9.35e-0444903GO:0060674
GeneOntologyBiologicalProcesspositive regulation of smoothened signaling pathway

SCUBE1 GLI1 SCUBE3

9.98e-0445903GO:0045880
GeneOntologyBiologicalProcessnegative regulation of angiogenesis

HSPG2 ADGRB2 THBS1 SEMA4A PLG

1.02e-03175905GO:0016525
GeneOntologyCellularComponentextracellular matrix

HSPG2 LAMB4 VWF ZAN LAMA1 LAMA2 LAMB2 SSPOP SVEP1 TGM2 THBS1 FBN2 MEGF9 SPOCK3 LTBP3 PLG LTBP4 FBN3

4.65e-106569218GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

HSPG2 LAMB4 VWF ZAN LAMA1 LAMA2 LAMB2 SSPOP SVEP1 TGM2 THBS1 FBN2 MEGF9 SPOCK3 LTBP3 PLG LTBP4 FBN3

4.89e-106589218GO:0030312
GeneOntologyCellularComponentcollagen-containing extracellular matrix

HSPG2 LAMB4 VWF LAMA1 LAMA2 LAMB2 SSPOP TGM2 THBS1 FBN2 MEGF9 LTBP3 PLG LTBP4

7.86e-085309214GO:0062023
GeneOntologyCellularComponentbasement membrane

HSPG2 LAMB4 LAMA1 LAMA2 LAMB2 MEGF9

1.65e-05122926GO:0005604
GeneOntologyCellularComponentmicrofibril

FBN2 LTBP4 FBN3

2.29e-0513923GO:0001527
GeneOntologyCellularComponentprotein complex involved in cell-matrix adhesion

LAMA1 LAMA2 LAMB2

5.36e-0517923GO:0098637
GeneOntologyCellularComponentlaminin-3 complex

LAMA1 LAMB2

5.73e-053922GO:0005608
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C RIMBP3B

2.50e-0428923GO:0002177
GeneOntologyCellularComponentlaminin complex

LAMA1 LAMB2

8.43e-0410922GO:0043256
GeneOntologyCellularComponentbeta-catenin-TCF complex

TCF7L2 PYGO2

1.45e-0313922GO:1990907
GeneOntologyCellularComponentprotein complex involved in cell adhesion

LAMA1 LAMA2 LAMB2

2.24e-0359923GO:0098636
MousePhenoabnormal pectoral girdle bone morphology

HSPG2 GSC SSPOP RNF113B FBN2 IGF2R TULP4 SCUBE3 DIP2C LTBP4

3.46e-063017310MP:0004508
MousePhenoabnormal sphenoid bone morphology

HSPG2 TCF7L2 GSC SCUBE1 PKD1 LTBP3

9.91e-0695736MP:0000104
MousePhenoabnormal axial skeleton morphology

HSPG2 TCF7L2 LAMA2 DLL1 GSC SSPOP THBS1 RNF113B SCUBE1 FBN2 IGF2R PYGO2 TULP4 KMT5B PKD1 SCUBE3 DIP2C LTBP3 LTBP4 NOTCH1 NOTCH2

1.09e-0514587321MP:0002114
MousePhenoabnormal heart valve morphology

HSPG2 ERBB3 TCF7L2 IGF2R TULP4 PKD1 NOTCH1

2.20e-05163737MP:0000285
MousePhenoabnormal neuron number

B4GALT2 CACNA1A ERBB3 WDR81 LAMA2 LAMB2 DLL1 SPOCK3 SEMA4A NOTCH1 HR

2.26e-054567311MP:0008946
MousePhenoabnormal thoracic cage morphology

HSPG2 GSC SSPOP RNF113B FBN2 IGF2R TULP4 SCUBE3 DIP2C LTBP3 LTBP4

2.60e-054637311MP:0004624
MousePhenoabnormal vertebral column morphology

HSPG2 TCF7L2 LAMA2 DLL1 GSC SSPOP THBS1 FBN2 KMT5B PKD1 SCUBE3 LTBP3 NOTCH1 NOTCH2

4.75e-057877314MP:0004703
MousePhenoabnormal sternum morphology

HSPG2 GSC SSPOP RNF113B IGF2R TULP4 DIP2C LTBP4

5.30e-05255738MP:0000157
MousePhenoabnormal neurocranium morphology

HSPG2 TCF7L2 LAMA2 GSC SCUBE1 PKD1 SCUBE3 LTBP3

7.72e-05269738MP:0000074
MousePhenoabnormal femur head morphology

HSPG2 GSC

8.04e-053732MP:0030788
MousePhenoabnormal retina neuronal layer morphology

LAMA1 WDR81 LAMB2 ZFPL1 DYRK1B SEMA4A BBS12 RSPO1 CRB2 HR

9.25e-054417310MP:0006069
MousePhenoabnormal vertebrae morphology

HSPG2 TCF7L2 DLL1 GSC FBN2 KMT5B PKD1 SCUBE3 LTBP3 NOTCH1 NOTCH2

1.15e-045467311MP:0000137
MousePhenoectopic manchette

RIMBP3 RIMBP3C RIMBP3B

1.25e-0419733MP:0009377
MousePhenoproctitis

PLG LTBP4

1.60e-044732MP:0003305
MousePhenodetached sperm flagellum

RIMBP3 RIMBP3C RIMBP3B

1.70e-0421733MP:0008893
MousePhenoabnormal appendicular skeleton morphology

HSPG2 DUSP3 GSC SSPOP RNF113B FBN2 IGF2R TULP4 PKD1 SCUBE3 DIP2C LTBP3 LTBP4 NOTCH2

1.89e-048967314MP:0009250
MousePhenodecreased susceptibility to induced morbidity/mortality

TNFRSF14 TGM2 SCUBE1 HABP2 PLG

2.27e-04106735MP:0009764
MousePhenoabnormal atrioventricular valve development

ERBB3 IGF2R

2.66e-045732MP:0031550
MousePhenoabnormal retina layer morphology

LAMA1 WDR81 LAMB2 ZFPL1 DYRK1B SEMA4A BBS12 RSPO1 CRB2 HR

2.74e-045047310MP:0003727
MousePhenopremature bone ossification

IGF2R PKD1 LTBP3

3.26e-0426733MP:0003416
MousePhenoabnormal miniature endplate potential

CACNA1A HSPG2 LAMB2

3.26e-0426733MP:0004835
MousePhenoabnormal inflammatory response

HSPG2 TCF7L2 VWF TNFRSF14 LAMA2 LAMB2 TGM2 THBS1 PKD1 HABP2 LTBP3 SEMA4A PLG LTBP4 BBS12 NOTCH1 HR

3.31e-0413107317MP:0001845
MousePhenoabnormal bone marrow cavity morphology

HSPG2 HIVEP3 PKD1

3.65e-0427733MP:0000065
MousePhenoabnormal forelimb morphology

HSPG2 TCF7L2 DUSP3 GSC FBN2 PKD1

3.71e-04182736MP:0000550
MousePhenoabnormal basicranium morphology

TCF7L2 LAMA2 GSC PKD1 LTBP3

4.53e-04123735MP:0010029
MousePhenoabnormal muscle morphology

HSPG2 ERBB3 TCF7L2 LAMA2 DLL1 GSC TGM2 THBS1 FBN2 IGF2R TULP4 PKD1 LTBP4 NOTCH1 NOTCH2

5.01e-0411067315MP:0002108
DomainEGF_1

HSPG2 LAMB4 ZAN LAMA1 NOTCH2NLA LAMA2 LAMB2 DLL1 NOTCH2NLC SSPOP SVEP1 THBS1 SCUBE1 FBN2 MEGF9 TENM1 SCUBE3 HABP2 LTBP3 LTBP4 FBN3 NOTCH1 MEGF10 NOTCH2 NOTCH4 CRB2

4.32e-272559426PS00022
DomainEGF_2

HSPG2 LAMB4 ZAN LAMA1 NOTCH2NLA LAMA2 LAMB2 DLL1 NOTCH2NLC SSPOP SVEP1 THBS1 SCUBE1 FBN2 MEGF9 TENM1 SCUBE3 HABP2 LTBP3 LTBP4 FBN3 NOTCH1 MEGF10 NOTCH2 NOTCH4 CRB2

1.19e-262659426PS01186
DomainEGF

HSPG2 ZAN LAMA1 NOTCH2NLA LAMA2 LAMB2 DLL1 NOTCH2NLC SVEP1 THBS1 SCUBE1 FBN2 MEGF9 TENM1 BRINP2 SCUBE3 HABP2 LTBP3 LTBP4 FBN3 NOTCH1 MEGF10 NOTCH2 NOTCH4 CRB2

1.63e-262359425SM00181
DomainEGF-like_CS

HSPG2 LAMB4 ZAN LAMA1 NOTCH2NLA LAMA2 LAMB2 DLL1 NOTCH2NLC SVEP1 THBS1 SCUBE1 FBN2 MEGF9 TENM1 SCUBE3 HABP2 LTBP3 LTBP4 FBN3 NOTCH1 MEGF10 NOTCH2 NOTCH4 CRB2

2.34e-252619425IPR013032
DomainEGF-like_dom

HSPG2 ZAN LAMA1 NOTCH2NLA LAMA2 LAMB2 DLL1 NOTCH2NLC SVEP1 THBS1 SCUBE1 FBN2 MEGF9 TENM1 SCUBE3 HABP2 LTBP3 LTBP4 FBN3 NOTCH1 MEGF10 NOTCH2 NOTCH4 CRB2

2.08e-242499424IPR000742
DomainEGF_3

HSPG2 ZAN NOTCH2NLA DLL1 NOTCH2NLC SSPOP SVEP1 THBS1 SCUBE1 FBN2 TENM1 SCUBE3 HABP2 LTBP3 LTBP4 FBN3 NOTCH1 MEGF10 NOTCH2 NOTCH4 CRB2

1.07e-202359421PS50026
DomainEGF_CA

HSPG2 NOTCH2NLA DLL1 NOTCH2NLC SVEP1 THBS1 SCUBE1 FBN2 SCUBE3 HABP2 LTBP3 LTBP4 FBN3 NOTCH1 NOTCH2 NOTCH4 CRB2

3.14e-201229417SM00179
DomainEGF-like_Ca-bd_dom

HSPG2 NOTCH2NLA DLL1 NOTCH2NLC SVEP1 THBS1 SCUBE1 FBN2 SCUBE3 HABP2 LTBP3 LTBP4 FBN3 NOTCH1 NOTCH2 NOTCH4 CRB2

4.19e-201249417IPR001881
DomainGrowth_fac_rcpt_

HSPG2 ERBB3 LAMA1 LAMB2 HTRA3 DLL1 SVEP1 SCUBE1 FBN2 SCUBE3 LTBP3 LTBP4 RSPO1 FBN3 NOTCH1 NOTCH2 NOTCH4

2.34e-181569417IPR009030
DomainEGF_Ca-bd_CS

NOTCH2NLA DLL1 NOTCH2NLC SVEP1 SCUBE1 FBN2 SCUBE3 LTBP3 LTBP4 FBN3 NOTCH1 NOTCH2 NOTCH4 CRB2

4.87e-17979414IPR018097
DomainEGF_CA

NOTCH2NLA DLL1 NOTCH2NLC SVEP1 SCUBE1 FBN2 SCUBE3 LTBP3 LTBP4 FBN3 NOTCH1 NOTCH2 NOTCH4 CRB2

6.56e-17999414PS01187
DomainASX_HYDROXYL

NOTCH2NLA DLL1 NOTCH2NLC SVEP1 SCUBE1 FBN2 SCUBE3 LTBP3 LTBP4 FBN3 NOTCH1 NOTCH2 NOTCH4 CRB2

7.60e-171009414PS00010
DomainhEGF

DLL1 SVEP1 FBN2 LTBP3 FBN3 NOTCH1 MEGF10 NOTCH2 NOTCH4 CRB2

7.76e-17289410PF12661
DomainEGF-type_Asp/Asn_hydroxyl_site

NOTCH2NLA DLL1 NOTCH2NLC SVEP1 SCUBE1 FBN2 SCUBE3 LTBP3 LTBP4 FBN3 NOTCH1 NOTCH2 NOTCH4 CRB2

1.77e-161069414IPR000152
DomainEGF_CA

NOTCH2NLA NOTCH2NLC SVEP1 THBS1 SCUBE1 FBN2 SCUBE3 LTBP3 LTBP4 FBN3 NOTCH1 NOTCH2 NOTCH4

3.63e-16869413PF07645
DomainEGF

HSPG2 ZAN NOTCH2NLA DLL1 NOTCH2NLC SVEP1 SCUBE3 HABP2 FBN3 NOTCH1 NOTCH2 NOTCH4 CRB2

6.05e-141269413PF00008
DomainLaminin_EGF

HSPG2 LAMB4 LAMA1 LAMA2 LAMB2 MEGF9 MEGF10

3.91e-1035947PF00053
DomainEGF_Lam

HSPG2 LAMB4 LAMA1 LAMA2 LAMB2 MEGF9 MEGF10

3.91e-1035947SM00180
DomainLaminin_EGF

HSPG2 LAMB4 LAMA1 LAMA2 LAMB2 MEGF9 MEGF10

7.24e-1038947IPR002049
DomainEGF_LAM_2

HSPG2 LAMB4 LAMA1 LAMA2 LAMB2 MEGF9

7.45e-0930946PS50027
DomainEGF_LAM_1

HSPG2 LAMB4 LAMA1 LAMA2 LAMB2 MEGF9

7.45e-0930946PS01248
DomainTB

FBN2 LTBP3 LTBP4 FBN3

2.08e-087944PF00683
Domain-

FBN2 LTBP3 LTBP4 FBN3

4.15e-0889443.90.290.10
DomainTB

FBN2 LTBP3 LTBP4 FBN3

7.44e-089944PS51364
DomainTB_dom

FBN2 LTBP3 LTBP4 FBN3

7.44e-089944IPR017878
DomaincEGF

SCUBE1 FBN2 SCUBE3 LTBP3 FBN3

1.75e-0726945IPR026823
DomaincEGF

SCUBE1 FBN2 SCUBE3 LTBP3 FBN3

1.75e-0726945PF12662
DomainNotch

NOTCH1 NOTCH2 NOTCH4

4.92e-074943IPR008297
DomainNODP

NOTCH1 NOTCH2 NOTCH4

4.92e-074943PF07684
DomainNotch_NODP_dom

NOTCH1 NOTCH2 NOTCH4

4.92e-074943IPR011656
DomainNotch_NOD_dom

NOTCH1 NOTCH2 NOTCH4

4.92e-074943IPR010660
DomainNOD

NOTCH1 NOTCH2 NOTCH4

4.92e-074943PF06816
DomainNOD

NOTCH1 NOTCH2 NOTCH4

4.92e-074943SM01338
DomainNODP

NOTCH1 NOTCH2 NOTCH4

4.92e-074943SM01339
DomainLaminin_N

LAMB4 LAMA1 LAMA2 LAMB2

1.05e-0616944IPR008211
DomainLAMININ_NTER

LAMB4 LAMA1 LAMA2 LAMB2

1.05e-0616944PS51117
DomainLaminin_N

LAMB4 LAMA1 LAMA2 LAMB2

1.05e-0616944PF00055
DomainLamNT

LAMB4 LAMA1 LAMA2 LAMB2

1.05e-0616944SM00136
DomainLNR

NOTCH1 NOTCH2 NOTCH4

1.23e-065943PS50258
DomainNotch_dom

NOTCH1 NOTCH2 NOTCH4

4.26e-067943IPR000800
DomainNotch

NOTCH1 NOTCH2 NOTCH4

4.26e-067943PF00066
DomainNL

NOTCH1 NOTCH2 NOTCH4

4.26e-067943SM00004
DomainLAMININ_IVA

HSPG2 LAMA1 LAMA2

6.79e-068943PS51115
DomainLaminin_B

HSPG2 LAMA1 LAMA2

6.79e-068943PF00052
DomainLamB

HSPG2 LAMA1 LAMA2

6.79e-068943SM00281
DomainLaminin_IV

HSPG2 LAMA1 LAMA2

6.79e-068943IPR000034
Domain-

HSPG2 LAMA1 LAMA2 SVEP1 THBS1 CRB2

8.38e-06959462.60.120.200
DomainLaminin_G

HSPG2 LAMA1 LAMA2 THBS1 CRB2

1.08e-0558945IPR001791
DomainConA-like_dom

HSPG2 ZAN LAMA1 LAMA2 TRIM6 SVEP1 THBS1 CRB2

1.47e-05219948IPR013320
DomainEphrin_rec_like

SVEP1 SCUBE1 SCUBE3

1.98e-0511943PF07699
DomainLaminin_G_1

HSPG2 LAMA1 LAMA2

1.98e-0511943PF00054
DomainTIL

VWF ZAN SSPOP

2.63e-0512943PF01826
DomainC8

VWF ZAN SSPOP

2.63e-0512943PF08742
DomainVWFC_1

VWF ZAN SSPOP THBS1

3.13e-0536944PS01208
DomainUnchr_dom_Cys-rich

VWF ZAN SSPOP

3.40e-0513943IPR014853
DomainC8

VWF ZAN SSPOP

3.40e-0513943SM00832
DomainVWC

VWF ZAN SSPOP THBS1

3.90e-0538944SM00214
DomainVWFC_2

VWF ZAN SSPOP THBS1

3.90e-0538944PS50184
DomainLAM_G_DOMAIN

HSPG2 LAMA1 LAMA2 CRB2

3.90e-0538944PS50025
DomainTIL_dom

VWF ZAN SSPOP

4.32e-0514943IPR002919
DomainLaminin_G_2

HSPG2 LAMA1 LAMA2 CRB2

4.79e-0540944PF02210
DomainVWF_dom

VWF ZAN SSPOP THBS1

5.82e-0542944IPR001007
DomainVWD

VWF ZAN SSPOP

6.59e-0516943SM00216
DomainVWF_type-D

VWF ZAN SSPOP

6.59e-0516943IPR001846
DomainVWFD

VWF ZAN SSPOP

6.59e-0516943PS51233
DomainVWD

VWF ZAN SSPOP

6.59e-0516943PF00094
DomainLamG

HSPG2 LAMA1 LAMA2 CRB2

7.00e-0544944SM00282
DomainDUF3454

NOTCH1 NOTCH2

7.49e-053942PF11936
DomainDUF3454_notch

NOTCH1 NOTCH2

7.49e-053942IPR024600
DomainLAMININ_IVB

LAMB4 LAMB2

7.49e-053942PS51116
DomainLaminin_IV_B

LAMB4 LAMB2

7.49e-053942IPR013015
DomainDUF3454

NOTCH1 NOTCH2

7.49e-053942SM01334
DomainFBN

FBN2 FBN3

7.49e-053942IPR011398
DomainVWC_out

VWF ZAN SSPOP

1.13e-0419943SM00215
DomainEGF_extracell

SVEP1 TENM1 NOTCH1 MEGF10

2.36e-0460944IPR013111
DomainEGF_2

SVEP1 TENM1 NOTCH1 MEGF10

2.36e-0460944PF07974
DomainLaminin_aI

LAMA1 LAMA2

2.48e-045942IPR009254
DomainLaminin_I

LAMA1 LAMA2

2.48e-045942PF06008
DomainLaminin_II

LAMA1 LAMA2

2.48e-045942PF06009
DomainLaminin_domII

LAMA1 LAMA2

2.48e-045942IPR010307
DomainEphrin_rec_like

SVEP1 SCUBE1 SCUBE3

2.62e-0425943SM01411
DomainTyr-kin_ephrin_A/B_rcpt-like

SVEP1 SCUBE1 SCUBE3

2.62e-0425943IPR011641
DomainTSP_1

ADGRB2 SSPOP THBS1 RSPO1

2.86e-0463944PF00090
DomainTNFR

TNFRSF14 TNFRSF6B MEGF9

2.95e-0426943SM00208
DomainTSP1

ADGRB2 SSPOP THBS1 RSPO1

3.22e-0465944SM00209
DomainTSP1_rpt

ADGRB2 SSPOP THBS1 RSPO1

3.22e-0465944IPR000884
DomainTSP1

ADGRB2 SSPOP THBS1 RSPO1

3.22e-0465944PS50092
DomainKringle-like

IGF2R HABP2 PLG

5.51e-0432943IPR013806
DomainTNFR/NGFR_Cys_rich_reg

TNFRSF14 TNFRSF6B MEGF9

6.04e-0433943IPR001368
DomainGalactose-bd-like

LAMA1 LAMA2 LAMB2 SSPOP

1.30e-0394944IPR008979
DomainEGF_3

SCUBE1 SCUBE3

1.60e-0312942PF12947
DomainEGF_dom

SCUBE1 SCUBE3

1.60e-0312942IPR024731
DomainDUF4599

SPATA31E1 SPATA31D1

1.60e-0312942PF15371
DomainDUF4599

SPATA31E1 SPATA31D1

1.60e-0312942IPR027970
DomainZnF_C3H1

MKRN4P MKRN1 RNF113B

1.81e-0348943SM00356
DomainLDLRA_1

HSPG2 SSPOP PKD1

1.81e-0348943PS01209
Domainzf-CCCH

MKRN4P MKRN1 RNF113B

1.92e-0349943PF00642
DomainCUB

CSMD2 SCUBE1 SCUBE3

1.92e-0349943PF00431
DomainLDLRA_2

HSPG2 SSPOP PKD1

1.92e-0349943PS50068
DomainCUB

CSMD2 SCUBE1 SCUBE3

2.04e-0350943SM00042
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

HSPG2 VWF LAMA1 LAMA2 LAMB2 THBS1 SCUBE1 FBN2 SPOCK3 SCUBE3 LTBP3 PLG LTBP4 FBN3

4.23e-113006314M610
PathwayKEGG_ECM_RECEPTOR_INTERACTION

HSPG2 LAMB4 VWF LAMA1 LAMA2 LAMB2 THBS1

8.74e-0884637M7098
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_SIGNALING_PATHWAY

DLL1 NOTCH1 NOTCH2 NOTCH4

2.51e-0713634M47423
PathwayREACTOME_DEFECTIVE_LFNG_CAUSES_SCDO3

NOTCH1 NOTCH2 NOTCH4

8.45e-075633M27411
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_THE_ENDOPLASMIC_RETICULUM

NOTCH1 NOTCH2 NOTCH4

1.69e-066633M27068
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

VWF THBS1 SCUBE1 FBN2 SPOCK3 SCUBE3 LTBP3 PLG LTBP4

2.00e-06258639MM14572
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

HSPG2 SCUBE1 FBN2 SPOCK3 SCUBE3 PLG FBN3

2.85e-06140637M587
PathwayKEGG_MEDICUS_REFERENCE_PLASMIN_MEDIATED_ACTIVATION_OF_LATENT_TGF_BETA

LTBP3 PLG LTBP4

4.69e-068633M47850
PathwayWP_CANONICAL_AND_NONCANONICAL_NOTCH_SIGNALING

DLL1 NOTCH1 NOTCH2 NOTCH4

5.88e-0627634M39545
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

HSPG2 LAMA1 LAMA2 LAMB2 THBS1

6.31e-0659635M27218
PathwayPID_NOTCH_PATHWAY

DLL1 SSPOP NOTCH1 NOTCH2 NOTCH4

6.31e-0659635M17
PathwayREACTOME_LAMININ_INTERACTIONS

HSPG2 LAMA1 LAMA2 LAMB2

9.10e-0630634M27216
PathwayPID_INTEGRIN1_PATHWAY

LAMA1 LAMA2 LAMB2 TGM2 THBS1

1.10e-0566635M18
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

SSPOP THBS1 NOTCH1 NOTCH2 NOTCH4

1.27e-0568635M27303
PathwayPID_INTEGRIN4_PATHWAY

LAMA1 LAMA2 LAMB2

1.37e-0511633M158
PathwayKEGG_MEDICUS_REFERENCE_NOTCH_PROTEOLYTIC_ACTIVATION

NOTCH1 NOTCH2 NOTCH4

1.37e-0511633M47865
PathwayBIOCARTA_HES_PATHWAY

DLL1 NOTCH1 NOTCH2

1.82e-0512633MM1562
PathwayBIOCARTA_HES_PATHWAY

DLL1 NOTCH1 NOTCH2

1.82e-0512633M22042
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00380

NOTCH1 NOTCH2 NOTCH4

1.82e-0512633M47532
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00381

NOTCH1 NOTCH2 NOTCH4

1.82e-0512633M47533
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN2 LTBP3 LTBP4 FBN3

2.14e-0537634M27134
PathwayKEGG_MEDICUS_PATHOGEN_HPV_E6_TO_NOTCH_SIGNALING_PATHWAY_N00382

NOTCH1 NOTCH2 NOTCH4

2.36e-0513633M47534
PathwayWP_DELTANOTCH_SIGNALING_PATHWAY

DLL1 HIVEP3 NOTCH1 NOTCH2 NOTCH4

3.18e-0582635MM15922
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

HSPG2 SSPOP THBS1 NOTCH1 NOTCH2 NOTCH4

4.14e-05143636M27275
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN2 LTBP3 LTBP4 FBN3

4.30e-0544634M26969
PathwayKEGG_MEDICUS_VARIANT_NOTCH_OVEREXPRESSION_TO_NOTCH_SIGNALING_PATHWAY

DLL1 NOTCH1 NOTCH4

4.57e-0516633M47424
PathwayWP_NOTCH_SIGNALING_WP268

DLL1 NOTCH1 NOTCH2 NOTCH4

4.70e-0545634M39571
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

ERBB3 LAMA1 LAMA2 LAMB2

5.13e-0546634M239
PathwayWP_NOTCH_SIGNALING_PATHWAY

DLL1 NOTCH1 NOTCH2 NOTCH4

5.13e-0546634MM15971
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

DLL1 NOTCH1 NOTCH2 NOTCH4

5.59e-0547634M7946
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH2 NOTCH4

6.62e-0518633M614
PathwayWP_CANCER_PATHWAYS

LAMB4 TCF7L2 LAMA1 LAMA2 LAMB2 DLL1 GLI1 NOTCH1 NOTCH2 NOTCH4

7.63e-055076310M48302
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

NOTCH1 NOTCH2 NOTCH4

9.19e-0520633M27881
PathwayREACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX

SCUBE1 FBN2 SPOCK3 SCUBE3 PLG

1.53e-04114635MM14571
PathwayWP_NOTCH_SIGNALING_WP61

DLL1 NOTCH1 NOTCH2 NOTCH4

1.56e-0461634M39540
PathwayKEGG_DORSO_VENTRAL_AXIS_FORMATION

NOTCH1 NOTCH2 NOTCH4

1.61e-0424633M11190
PathwayREACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI

NOTCH1 NOTCH4

1.95e-045632MM14733
PathwayKEGG_FOCAL_ADHESION

LAMB4 VWF LAMA1 LAMA2 LAMB2 THBS1

2.55e-04199636M7253
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH2 NOTCH4

2.57e-0428633M6177
PathwayBIOCARTA_NOTCH_PATHWAY

DLL1 NOTCH1

2.91e-046632MM1584
PathwayBIOCARTA_NOTCH_PATHWAY

DLL1 NOTCH1

2.91e-046632M22074
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMA1 LAMA2 LAMB2

3.17e-0430633M27772
PathwayREACTOME_ECM_PROTEOGLYCANS

HSPG2 LAMA1 LAMA2 LAMB2

3.65e-0476634M27219
PathwayPID_SYNDECAN_4_PATHWAY

LAMA1 THBS1 PLG

3.85e-0432633M165
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN2 LTBP3 LTBP4

3.85e-0432633MM14854
PathwayREACTOME_SIGNALING_BY_NOTCH1_T_7_9_NOTCH1_M1580_K2555_TRANSLOCATION_MUTANT

DLL1 NOTCH1

4.07e-047632M27199
PathwayREACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING

NOTCH1 NOTCH4

4.07e-047632MM14734
PathwayWP_ALPHA_6_BETA_4_SIGNALING

LAMA1 LAMA2 LAMB2

4.22e-0433633M39503
PathwayWP_OSX_AND_MIRNAS_IN_TOOTH_DEVELOPMENT

NOTCH1 NOTCH2 NOTCH4

4.61e-0434633M39390
PathwayKEGG_SMALL_CELL_LUNG_CANCER

LAMB4 LAMA1 LAMA2 LAMB2

5.35e-0484634M3228
PathwayWP_BREAST_CANCER_PATHWAY

TCF7L2 DLL1 NOTCH1 NOTCH2 NOTCH4

6.15e-04154635M39739
PathwayREACTOME_SIGNALING_BY_NOTCH

DLL1 NOTCH1 NOTCH4

6.93e-0439633MM14604
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN2 LTBP3 LTBP4

6.93e-0439633MM14601
PathwayWP_SOMITOGENESIS_IN_THE_CONTEXT_OF_SPONDYLOCOSTAL_DYSOSTOSIS

DLL1 NOTCH1

6.93e-049632M39869
PathwayWP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER

DLL1 PKD1 NOTCH1 NOTCH2 NOTCH4

7.52e-04161635M39770
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMA1 LAMA2 LAMB2

8.03e-0441633M27778
PathwayREACTOME_DISEASES_OF_METABOLISM

HSPG2 SSPOP THBS1 NOTCH1 NOTCH2 NOTCH4

8.55e-04250636M27554
PathwayWP_GENE_REGULATORY_NETWORK_MODELLING_SOMITOGENESIS

DLL1 NOTCH1

8.64e-0410632MM15839
PathwayWP_SMALL_CELL_LUNG_CANCER

LAMB4 LAMA1 LAMA2 LAMB2

8.85e-0496634M39834
PathwayWP_NEURAL_CREST_DIFFERENTIATION

DLL1 NOTCH1 NOTCH2 NOTCH4

9.20e-0497634MM15926
PathwayWP_GENE_REGULATORY_NETWORK_MODELING_SOMITOGENESIS

DLL1 NOTCH1

1.05e-0311632M39647
PathwayWP_NEURAL_CREST_DIFFERENTIATION

DLL1 NOTCH1 NOTCH2 NOTCH4

1.07e-03101634M39448
PathwayPID_PS1_PATHWAY

DLL1 SSPOP NOTCH1

1.13e-0346633M70
PathwayREACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL

MKRN4P MKRN1

1.26e-0312632MM14777
PathwayWP_FOCAL_ADHESION

VWF LAMA1 LAMA2 LAMB2 THBS1

1.47e-03187635MM15913
PathwayBIOCARTA_PS1_PATHWAY

DLL1 NOTCH1

1.73e-0314632MM1459
PathwayBIOCARTA_PS1_PATHWAY

DLL1 NOTCH1

1.73e-0314632M16173
PathwayWP_OSTEOBLAST_DIFFERENTIATION_AND_RELATED_DISEASES

DLL1 NOTCH1 NOTCH2 NOTCH4

1.90e-03118634M39852
PathwayWP_FOCAL_ADHESION

VWF LAMA1 LAMA2 LAMB2 THBS1

1.93e-03199635M39402
PathwayREACTOME_SIGNALING_BY_NOTCH1_HD_DOMAIN_MUTANTS_IN_CANCER

DLL1 NOTCH1

1.99e-0315632M27202
PathwayBIOCARTA_SHH_PATHWAY

GLI1 DYRK1B

1.99e-0315632MM1498
PathwayWP_NEUROGENESIS_REGULATION_IN_THE_OLFACTORY_EPITHELIUM

DLL1 SEMA4A NOTCH1

2.10e-0357633M48326
PathwayBIOCARTA_SHH_PATHWAY

GLI1 DYRK1B

2.27e-0316632M11792
PathwayWP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS

TCF7L2 NOTCH1

2.56e-0317632M39443
PathwayREACTOME_FORMATION_OF_DEFINITIVE_ENDODERM

TCF7L2 GSC

2.56e-0317632M48030
PathwayWP_NOTCH1_REGULATION_OF_ENDOTHELIAL_CELL_CALCIFICATION

DLL1 NOTCH1

2.56e-0317632M39389
PathwayREACTOME_GASTRULATION

TCF7L2 DLL1 GSC NOTCH1

2.63e-03129634M46433
PathwayWP_DYRK1A_INVOLVEMENT_REGARDING_CELL_PROLIFERATION_IN_BRAIN_DEVELOPMENT

DLL1 GLI1 NOTCH1

2.67e-0362633M45532
PathwayWP_NEPHROGENESIS

RSPO1 NOTCH2

2.87e-0318632M40045
PathwayWP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY

LAMA1 LAMA2 LAMB2

3.19e-0366633MM15925
PathwayKEGG_PATHWAYS_IN_CANCER

LAMB4 TCF7L2 LAMA1 LAMA2 LAMB2 GLI1

3.23e-03325636M12868
PathwayWP_PI3KAKT_SIGNALING

LAMB4 VWF LAMA1 LAMA2 LAMB2 THBS1

3.97e-03339636M39736
PathwayWP_BLOOD_CLOTTING_CASCADE

VWF PLG

4.29e-0322632M39480
PathwayREACTOME_NOTCH2_ACTIVATION_AND_TRANSMISSION_OF_SIGNAL_TO_THE_NUCLEUS

DLL1 NOTCH2

4.29e-0322632M27210
PathwayREACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY

NOTCH1 NOTCH4

4.68e-0323632MM14954
PathwayWP_BLOOD_CLOTTING_CASCADE

VWF PLG

4.68e-0323632MM15936
PathwayREACTOME_SIGNALING_BY_MET

LAMA1 LAMA2 LAMB2

5.28e-0379633M27643
PathwayWP_HYPOTHESIZED_PATHWAYS_IN_PATHOGENESIS_OF_CARDIOVASCULAR_DISEASE

FBN2 FBN3

5.52e-0325632M39713
PathwayREACTOME_SIGNALING_BY_NOTCH4

NOTCH1 NOTCH2 NOTCH4

5.86e-0382633M594
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TCF7L2 PYGO2

5.96e-0326632MM14793
PathwayREACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS

HSPG2 VWF THBS1

6.48e-0385633M16441
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

HSPG2 VWF LAMA1 LAMA2 LAMB2 SSPOP TGM2 THBS1 FBN2 PLG LTBP4

2.61e-12175971128071719
Pubmed

Evolution of Human Brain Size-Associated NOTCH2NL Genes Proceeds toward Reduced Protein Levels.

NOTCH2NLA NOTCH2NLC NOTCH2NLB NOTCH2

5.68e-11497432330268
Pubmed

Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis.

NOTCH2NLA NOTCH2NLC NOTCH2NLB NOTCH2

2.84e-10597429856954
Pubmed

Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation.

NOTCH2NLA DLL1 NOTCH2NLC NOTCH2NLB

2.84e-10597429856955
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

HSPG2 VWF LAMA1 LAMA2 LAMB2 TGM2 THBS1 PLG LTBP4

1.09e-0916797922159717
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ZXDC HSPG2 ADGRB2 LAMB2 DLL1 HIVEP3 VOPP1 IGF2R TULP4 GLI1 PKD1 DIP2C WDR90 LTBP3 LTBP4 NOTCH1 NOTCH2 HR

1.49e-091105971835748872
Pubmed

Human ligands of the Notch receptor.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.98e-09797410079256
Pubmed

The distribution of Notch receptors and their ligands during articular cartilage development.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.98e-09797412846471
Pubmed

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear.

DLL1 NOTCH1 NOTCH2 NOTCH4

3.95e-0989749858718
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

HSPG2 VWF LAMA2 LAMB2 TGM2 FBN2 PLG LTBP4

4.52e-0913597828675934
Pubmed

Dynamic expression patterns of the pudgy/spondylocostal dysostosis gene Dll3 in the developing nervous system.

DLL1 NOTCH1 NOTCH2 NOTCH4

7.09e-09997411118901
Pubmed

Notch1 signals through Jagged2 to regulate apoptosis in the apical ectodermal ridge of the developing limb bud.

DLL1 NOTCH1 NOTCH2 NOTCH4

7.09e-09997416245338
Pubmed

Spatiotemporal expression of Notch receptors and ligands in developing mouse placenta.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.18e-081097423665443
Pubmed

A family of mammalian Fringe genes implicated in boundary determination and the Notch pathway.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.85e-08119749187150
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.85e-081197415499562
Pubmed

Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.85e-081197410878608
Pubmed

Notch-associated gene expression in embryonic and adult taste papillae and taste buds suggests a role in taste cell lineage decisions.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.85e-081197412866128
Pubmed

Differential expression of Notch genes in human osteoblastic cells.

NOTCH1 NOTCH2 NOTCH4

2.10e-08397311836628
Pubmed

Integrity of intracellular domain of Notch ligand is indispensable for cleavage required for release of the Notch2 intracellular domain.

DLL1 NOTCH2 NOTCH4

2.10e-08397311823422
Pubmed

Notch signaling: cell fate control and signal integration in development.

NOTCH1 NOTCH2 NOTCH4

2.10e-08397310221902
Pubmed

Notch signaling confers antigen-presenting cell functions on mast cells.

DLL1 NOTCH1 NOTCH2

2.10e-08397319130928
Pubmed

Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells.

DLL1 NOTCH1 NOTCH2

2.10e-08397315976178
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

HSPG2 LAMA1 LAMA2 LAMB2 SSPOP THBS1

2.65e-086497622261194
Pubmed

Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.

DLL1 NOTCH1 NOTCH2 NOTCH4

2.77e-081297415465494
Pubmed

Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium.

DLL1 NOTCH1 NOTCH2 NOTCH4

2.77e-081297410952889
Pubmed

Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.

DLL1 NOTCH1 NOTCH2 NOTCH4

3.99e-081397411578869
Pubmed

Inhibition of notch1-dependent cardiomyogenesis leads to a dilated myopathy in the neonatal heart.

VWF NOTCH1 NOTCH2 NOTCH4

3.99e-081397420558824
Pubmed

Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.

CACNA1A HSPG2 VWF LAMB2 LTBP3 LTBP4 NOTCH1

4.32e-0811897721078624
Pubmed

Cell-fate transition and determination analysis of mouse male germ cells throughout development.

ZXDC NOTCH1 NOTCH2 NOTCH4

5.57e-081497434824237
Pubmed

Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.

DLL1 NOTCH1 NOTCH2 NOTCH4

5.57e-081497414757642
Pubmed

Expression of Notch pathway genes in the embryonic mouse metanephros suggests a role in proximal tubule development.

DLL1 NOTCH1 NOTCH2 NOTCH4

7.58e-081597412971992
Pubmed

Basement membrane composition in the early mouse embryo day 7.

HSPG2 LAMA1 LAMA2 LAMB2

7.58e-081597415895400
Pubmed

The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497324145721
Pubmed

A switch in Notch gene expression parallels stem cell to endothelial transition in infantile hemangioma.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497320069356
Pubmed

Expression and clinical significance of Notch receptors in human renal cell carcinoma.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497319404845
Pubmed

Notch signaling pathway regulates the growth and the expression of inflammatory cytokines in mouse basophils.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497328669409
Pubmed

Differential regulation of osteoclastogenesis by Notch2/Delta-like 1 and Notch1/Jagged1 axes.

DLL1 NOTCH1 NOTCH2

8.40e-08497322390640
Pubmed

Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex.

NOTCH2NLA NOTCH2NLC NOTCH2NLB

8.40e-08497329561261
Pubmed

Characterization and developmental expression of the amphioxus homolog of Notch (AmphiNotch): evolutionary conservation of multiple expression domains in amphioxus and vertebrates.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497311401408
Pubmed

Functional conservation of mouse Notch receptor family members.

NOTCH1 NOTCH2 NOTCH4

8.40e-0849738898100
Pubmed

Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane.

DLL1 NOTCH1 NOTCH2

8.40e-0849739244302
Pubmed

Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.

LAMA1 LAMA2 LAMB2

8.40e-0849732099832
Pubmed

Notch pathway activity identifies cells with cancer stem cell-like properties and correlates with worse survival in lung adenocarcinoma.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497323444212
Pubmed

Deregulated expression of Notch receptors in human hepatocellular carcinoma.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497317920003
Pubmed

Prognostic roles of mRNA expression of notch receptors in non-small cell lung cancer.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497328061457
Pubmed

Canonical Notch ligands and Fringes have distinct effects on NOTCH1 and NOTCH2.

DLL1 NOTCH1 NOTCH2

8.40e-08497332820046
Pubmed

Evolutionary analysis of vertebrate Notch genes.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497311466531
Pubmed

Abnormal expression pattern of Notch receptors, ligands, and downstream effectors in the dorsolateral prefrontal cortex and amygdala of suicidal victims.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497324151014
Pubmed

Notch as a mediator of cell fate determination in hematopoiesis: evidence and speculation.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497310194420
Pubmed

Notch controls the survival of memory CD4+ T cells by regulating glucose uptake.

DLL1 NOTCH1 NOTCH2

8.40e-08497325501905
Pubmed

Conservation of the biochemical mechanisms of signal transduction among mammalian Notch family members.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497311459941
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

8.40e-08497319091768
Pubmed

Mutational analysis of NOTCH1, 2, 3 and 4 genes in common solid cancers and acute leukemias.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497318184405
Pubmed

Notch signaling in the mammalian central nervous system: insights from mouse mutants.

NOTCH1 NOTCH2 NOTCH4

8.40e-08497315917835
Pubmed

Transcriptome-based systematic identification of extracellular matrix proteins.

HSPG2 LAMA1 LAMA2 LAMB2 THBS1 SPOCK3

9.49e-087997618757743
Pubmed

Expression of Notch pathway components in fetal and adult mouse small intestine.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.01e-071697412617809
Pubmed

An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.01e-071697417273555
Pubmed

Requirement of Math1 for secretory cell lineage commitment in the mouse intestine.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.01e-071697411739954
Pubmed

Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.

HSPG2 LAMA1 LAMA2 LAMB2

1.01e-071697417948866
Pubmed

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.

LAMA1 DLL1 NOTCH1 NOTCH2

1.01e-071697417229764
Pubmed

Notch gene expression during pancreatic organogenesis.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.01e-071697410842072
Pubmed

Gamma-secretase activation of notch signaling regulates the balance of proximal and distal fates in progenitor cells of the developing lung.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.32e-071797418694942
Pubmed

Segmental expression of Notch and Hairy genes in nephrogenesis.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.32e-071797415821257
Pubmed

Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.32e-071797439315665
Pubmed

Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.

LAMA1 LAMB2 THBS1 SPOCK3 PKD1 LTBP3 RSPO1 NOTCH1

1.41e-0721097816537572
Pubmed

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.69e-071897418093989
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

LAMB4 LAMA1 LAMA2 LAMB2

1.69e-071897411311202
Pubmed

RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.

DLL1 NOTCH1 NOTCH2 NOTCH4

1.69e-071897415689374
Pubmed

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.

HSPG2 VWF LAMA2 LAMB2 THBS1 LTBP3 LTBP4

1.86e-0714697727068509
Pubmed

Immunohistochemical expression of Notch signaling in the lining epithelium of periapical cysts.

DLL1 NOTCH1 NOTCH2

2.09e-07597321238798
Pubmed

MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.

NOTCH1 NOTCH2 NOTCH4

2.09e-07597311101851
Pubmed

The notch receptor and its ligands are selectively expressed during hematopoietic development in the mouse.

DLL1 NOTCH1 NOTCH2

2.09e-07597311713346
Pubmed

Squamous odontogenic tumor of the mandible: a case report demonstrating immunoexpression of Notch1, 3, 4, Jagged1 and Delta1.

DLL1 NOTCH1 NOTCH4

2.09e-07597320554499
Pubmed

Expression patterns of Notch receptors and their ligands Jagged and Delta in human placenta.

DLL1 NOTCH2 NOTCH4

2.09e-07597321726900
Pubmed

Notch and MAML-1 complexation do not detectably alter the DNA binding specificity of the transcription factor CSL.

NOTCH1 NOTCH2 NOTCH4

2.09e-07597321124806
Pubmed

Intraovarian regulation of gonadotropin-dependent folliculogenesis depends on notch receptor signaling pathways not involving Delta-like ligand 4 (Dll4).

NOTCH1 NOTCH2 NOTCH4

2.09e-07597323675950
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

2.09e-07597317855024
Pubmed

Functional redundancy of the Notch gene family during mouse embryogenesis: analysis of Notch gene expression in Notch3-deficient mice.

NOTCH1 NOTCH2 NOTCH4

2.09e-07597315882997
Pubmed

Notch signaling mediated by Delta-like ligands 1 and 4 controls the pathogenesis of chronic GVHD in mice.

DLL1 NOTCH1 NOTCH2

2.09e-07597330181175
Pubmed

Association of Notch pathway down-regulation with Triple Negative/Basal-like breast carcinomas and high tumor-infiltrating FOXP3+ Tregs.

NOTCH1 NOTCH2 NOTCH4

2.09e-07597327118257
Pubmed

Notch 2 and Notch 1/3 segregate to neuronal and glial lineages of the developing olfactory epithelium.

DLL1 NOTCH1 NOTCH2 NOTCH4

2.13e-071997416518823
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

HSPG2 VWF LAMA2 LAMB2 TGM2 PLG LTBP4

2.56e-0715397725037231
Pubmed

Neurovascular EGFL7 regulates adult neurogenesis in the subventricular zone and thereby affects olfactory perception.

DLL1 NOTCH1 NOTCH2 NOTCH4

3.28e-072197428656980
Pubmed

RBP-L, a transcription factor related to RBP-Jkappa.

NOTCH1 NOTCH2 NOTCH4

4.18e-0769739111338
Pubmed

Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilization.

LAMA1 LAMA2 LAMB2

4.18e-0769731678389
Pubmed

Binding of Delta1, Jagged1, and Jagged2 to Notch2 rapidly induces cleavage, nuclear translocation, and hyperphosphorylation of Notch2.

DLL1 NOTCH1 NOTCH2

4.18e-07697310958687
Pubmed

Characterization of Notch receptor expression in the developing mammalian heart and liver.

NOTCH1 NOTCH2 NOTCH4

4.18e-07697312244553
Pubmed

Interaction with factor inhibiting HIF-1 defines an additional mode of cross-coupling between the Notch and hypoxia signaling pathways.

NOTCH1 NOTCH2 NOTCH4

4.18e-07697318299578
Pubmed

Impaired primary mouse myotube formation on crosslinked type I collagen films is enhanced by laminin and entactin.

LAMA1 LAMA2 LAMB2

4.18e-07697326555376
Pubmed

Effect of basement membrane entactin on epidermal cell attachment and growth.

LAMA1 LAMA2 LAMB2

4.18e-0769733794389
Pubmed

Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation.

DLL1 NOTCH1 NOTCH2

4.18e-0769739882480
Pubmed

Cloning and functional characterization of the murine mastermind-like 1 (Maml1) gene.

NOTCH1 NOTCH2 NOTCH4

4.18e-07697315019995
Pubmed

Notch controls the magnitude of T helper cell responses by promoting cellular longevity.

NOTCH1 NOTCH2 NOTCH4

4.18e-07697322615412
Pubmed

Laminin-nidogen complex. Extraction with chelating agents and structural characterization.

LAMA1 LAMA2 LAMB2

4.18e-0769733109910
Pubmed

Structural elucidation of full-length nidogen and the laminin-nidogen complex in solution.

LAMA1 LAMA2 LAMB2

4.18e-07697323948589
Pubmed

Notch signaling is a critical regulator of allogeneic CD4+ T-cell responses mediating graft-versus-host disease.

NOTCH1 NOTCH2 NOTCH4

4.18e-07697320870902
Pubmed

Entactin: structure and function.

LAMA1 LAMA2 LAMB2

4.18e-0769732119632
Pubmed

GAS1 is required for NOTCH-dependent facilitation of SHH signaling in the ventral forebrain neuroepithelium.

DLL1 GLI1 NOTCH1

4.18e-07697334698766
Pubmed

Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding site.

NOTCH1 NOTCH2 NOTCH4

4.18e-07697318239137
Pubmed

Notch4 Negatively Regulates the Inflammatory Response to Mycobacterium tuberculosis Infection by Inhibiting TAK1 Activation.

NOTCH1 NOTCH2 NOTCH4

4.18e-07697329228365
InteractionNTN5 interactions

FBN2 LTBP4 NOTCH1 NOTCH2

4.21e-0624934int:NTN5
InteractionZNF408 interactions

HSPG2 LAMA1 NOTCH2NLA FBN2 ZNF764 LTBP4 NOTCH2

4.88e-06145937int:ZNF408
InteractionPRG2 interactions

HSPG2 TNFRSF6B LAMB2 THBS1 FBN2 LTBP3 LTBP4 NOTCH1 NOTCH2

6.79e-06285939int:PRG2
InteractionCACNA1A interactions

CACNA1A HSPG2 VWF LTBP3 LTBP4 NOTCH1

2.26e-05123936int:CACNA1A
InteractionIGFL3 interactions

LAMA1 LAMB2 FBN2 NOTCH1 NOTCH2

2.51e-0575935int:IGFL3
InteractionCFC1 interactions

TNFRSF6B LAMB2 THBS1 LTBP4 NOTCH1 NOTCH2

2.59e-05126936int:CFC1
InteractionFBLN1 interactions

CACNA1A HSPG2 TCF7L2 ZNF764 LTBP4 NOTCH2

2.96e-05129936int:FBLN1
InteractionTOP3B interactions

ZXDC HSPG2 ADGRB2 LAMB2 DLL1 HIVEP3 VOPP1 IGF2R TULP4 GLI1 PKD1 SNRNP40 DIP2C WDR90 LTBP3 LTBP4 NOTCH1 NOTCH2 HR

3.50e-0514709319int:TOP3B
InteractionMAML2 interactions

NOTCH1 NOTCH2 NOTCH4

6.17e-0517933int:MAML2
InteractionLTBP1 interactions

CACNA1A LAMA2 TGM2 FBN2 NOTCH2

6.73e-0592935int:LTBP1
InteractionFOXD4L6 interactions

FBN2 LTBP4 NOTCH1 NOTCH2

7.68e-0549934int:FOXD4L6
InteractionMFAP5 interactions

VWF DLL1 FBN2 LTBP4

9.71e-0552934int:MFAP5
InteractionMAML3 interactions

NOTCH1 NOTCH2 NOTCH4

1.02e-0420933int:MAML3
InteractionEDN3 interactions

HSPG2 TNFRSF6B LAMB2 NOTCH1 NOTCH2

1.44e-04108935int:EDN3
InteractionNOTCH2 interactions

ZXDC LAMB2 DLL1 ZFPL1 FBN2 LTBP4 NOTCH1 NOTCH2 NOTCH4

1.47e-04423939int:NOTCH2
InteractionJAG2 interactions

CACNA1A ZFPL1 PLPPR2 NOTCH1 NOTCH2

1.57e-04110935int:JAG2
InteractionHRG interactions

THBS1 FBN2 PLG LTBP4

2.06e-0463934int:HRG
InteractionSCUBE1 interactions

SCUBE1 SCUBE3

2.09e-045932int:SCUBE1
InteractionVWCE interactions

LAMB2 FBN2 ZNF764 LTBP4

2.18e-0464934int:VWCE
InteractionSPARC interactions

HSPG2 TGM2 THBS1 PLG

2.32e-0465934int:SPARC
InteractionFBN2 interactions

SVEP1 THBS1 FBN2 NOTCH2

2.32e-0465934int:FBN2
InteractionHOXA1 interactions

VWF NOTCH2NLA LAMB2 SLC15A3 LTBP3 LTBP4 NOTCH1 HR

2.42e-04356938int:HOXA1
InteractionRBL1 interactions

TCF7L2 LAMB2 KMT5B DYRK1B SNRNP40

2.45e-04121935int:RBL1
InteractionLAMA1 interactions

HSPG2 LAMA1 TGM2 PLG

2.46e-0466934int:LAMA1
InteractionMFNG interactions

DLL1 NOTCH1 NOTCH2

2.57e-0427933int:MFNG
InteractionLTBP4 interactions

CACNA1A ZNF764 LTBP4 NOTCH2

2.61e-0467934int:LTBP4
CytobandEnsembl 112 genes in cytogenetic band chr1p35

ADGRB2 TMEM39B CSMD2 SNRNP40

2.12e-04137974chr1p35
Cytoband6q26

IGF2R PLG

6.61e-04189726q26
Cytoband19p13

CACNA1A FBN3

1.50e-032797219p13
CytobandEnsembl 112 genes in cytogenetic band chr1q21

NOTCH2NLA LCE6A NOTCH2NLC PYGO2 NOTCH2NLB

1.71e-03404975chr1q21
Cytoband22q11.21

RIMBP3 RIMBP3C RIMBP3B

1.72e-0311197322q11.21
Cytoband10q25.3

TCF7L2 HABP2

1.73e-032997210q25.3
CytobandXp21.1

MKRN4P FAM47B

2.37e-0334972Xp21.1
GeneFamilyLaminin subunits

LAMB4 LAMA1 LAMA2 LAMB2

5.32e-0812604626
GeneFamilyLatent transforming growth factor beta binding proteins

LTBP3 LTBP4

6.47e-054602628
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CFHR5 CSMD2 SVEP1

8.95e-04576031179
CoexpressionNABA_MATRISOME

HSPG2 LAMB4 VWF LAMA1 LAMA2 LAMB2 HTRA3 SSPOP SVEP1 TGM2 THBS1 SCUBE1 FBN2 MEGF9 SPOCK3 BRINP2 SCUBE3 HABP2 LTBP3 SEMA4A PLG LTBP4 RSPO1 FBN3 MEGF10

2.00e-1410269525M5889
CoexpressionNABA_CORE_MATRISOME

HSPG2 LAMB4 VWF LAMA1 LAMA2 LAMB2 SSPOP SVEP1 THBS1 FBN2 SPOCK3 LTBP3 LTBP4 RSPO1 FBN3

7.31e-142759515M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

LAMB4 VWF LAMA1 LAMA2 LAMB2 SSPOP SVEP1 THBS1 FBN2 LTBP3 LTBP4 RSPO1 FBN3

3.12e-131969513M3008
CoexpressionNABA_MATRISOME

HSPG2 VWF LAMA1 LAMA2 LAMB2 HTRA3 SSPOP SVEP1 TGM2 THBS1 SCUBE1 FBN2 MEGF9 SPOCK3 BRINP2 SCUBE3 HABP2 LTBP3 SEMA4A PLG LTBP4 RSPO1 MEGF10

1.04e-1210089523MM17056
CoexpressionNABA_CORE_MATRISOME

HSPG2 VWF LAMA1 LAMA2 LAMB2 SSPOP SVEP1 THBS1 FBN2 SPOCK3 LTBP3 LTBP4 RSPO1

1.81e-112709513MM17057
CoexpressionNABA_ECM_GLYCOPROTEINS

VWF LAMA1 LAMA2 LAMB2 SSPOP SVEP1 THBS1 FBN2 LTBP3 LTBP4 RSPO1

1.06e-101919511MM17059
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

DLL1 NOTCH1 NOTCH2 NOTCH4

2.85e-0716954MM1296
CoexpressionFUKUSHIMA_TNFSF11_TARGETS

DLL1 NOTCH1 NOTCH2 NOTCH4

2.85e-0716954M2207
CoexpressionNABA_BASEMENT_MEMBRANES

HSPG2 LAMB4 LAMA1 LAMA2 LAMB2

3.35e-0740955M5887
CoexpressionFAN_EMBRYONIC_CTX_EX_4_EXCITATORY_NEURON

CACNA1A PCLO CSMD2 PKD1 LTBP4 TARBP1 FBN3

2.49e-06166957M39026
CoexpressionHALLMARK_NOTCH_SIGNALING

TCF7L2 DLL1 NOTCH1 NOTCH2

5.39e-0632954M5903
CoexpressionBENPORATH_ES_WITH_H3K27ME3

CACNA1A ADGRB2 HTRA3 CSMD2 GSC RIMBP3 FBN2 SPOCK3 BRINP2 SCUBE3 RIMBP3C SOX14 RIMBP3B RSPO1 HR

1.12e-0511159515M10371
CoexpressionBENPORATH_SUZ12_TARGETS

CACNA1A GPR50 NOTCH2NLA ADGRB2 GSC RIMBP3 FBN2 SPOCK3 BRINP2 RIMBP3C SOX14 RIMBP3B RSPO1 NOTCH2

2.13e-0510359514M9898
CoexpressionVERRECCHIA_RESPONSE_TO_TGFB1_C1

HSPG2 TCF7L2 NOTCH2

4.29e-0519953M16026
CoexpressionVERRECCHIA_EARLY_RESPONSE_TO_TGFB1

HSPG2 TCF7L2 IGF2R NOTCH2

4.46e-0554954M4737
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBGABA

CACNA1A PCLO TNFRSF6B CSMD2 VOPP1 TULP4 SPOCK3 TENM1 BRINP2 SOX14 TARBP1

4.83e-057039511M39070
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS

HSPG2 LAMA1 LAMB2

7.75e-0523953M48001
CoexpressionHALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION

LAMA1 LAMA2 TGM2 THBS1 FBN2 NOTCH2

9.05e-05200956M5930
CoexpressionGSE24492_LYVE_NEG_VS_POS_MACROPHAGE_DN

HSPG2 MKRN1 USF3 SPOCK3 BRINP2 PLG

9.05e-05200956M7873
CoexpressionGSE2405_HEAT_KILLED_LYSATE_VS_LIVE_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_24H_DN

DUSP3 HTRA3 ZNF764 RIMBP3C WDR90 SEMA4A

9.05e-05200956M6201
CoexpressionPEDRIOLI_MIR31_TARGETS_DN

VWF PCLO NOTCH2NLA TNFRSF6B LAMA2 HTRA3 UHMK1 DIP2C

1.31e-04413958M2494
CoexpressionVART_KSHV_INFECTION_ANGIOGENIC_MARKERS_DN

DLL1 THBS1 PLG NOTCH1 NOTCH2

1.34e-04135955M5825
CoexpressionPILON_KLF1_TARGETS_UP

MKRN4P VWF MKRN1 DLL1 DENND2B VOPP1 FBN2 KMT5B PLG

1.55e-04541959MM1061
CoexpressionHEBERT_MATRISOME_TNBC_LUNG_METASTASIS_TUMOR_CELL_DERIVED

LAMA1 LAMB2

1.93e-046952M48000
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

HSPG2 PDE3A LAMA2 LAMB2 HTRA3 SLC15A3 DENND2B SVEP1 TGM2 THBS1 LTBP3 LTBP4

9.04e-074669312GSM777050_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

PDE3A LAMA1 LAMA2 TTK DENND2B SVEP1 TGM2 THBS1 SCUBE1 FBN2 IGF2R GLI1 LTBP4 NOTCH2

6.98e-067779314gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#1

CACNA1A PCLO DLL1 THBS1 TULP4 SEMA4A LTBP4 PLPPR2

1.64e-05255938Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000_K1
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2

HSPG2 ADGRB2 WDR81 LAMB2 HTRA3 SVEP1 TGM2 THBS1 SCUBE1 FBN2 IGF2R GLI1 PKD1 LTBP3 LTBP4 RSPO1 PLPPR2

2.14e-0512289317facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2
CoexpressionAtlasStromal Cells, BEC.MLN, gp38- CD31+, Lymph Node, avg-5

HSPG2 VWF DUSP3 LAMB2 DLL1 BCL6B TGM2 THBS1 LTBP4 NOTCH4

3.11e-054569310GSM777032_500
CoexpressionAtlasStromal Cells, BEC.SLN, gp38- CD31+, Lymph Node, avg-4

HSPG2 VWF DUSP3 LAMB2 DLL1 BCL6B TGM2 THBS1 LTBP4 NOTCH4

3.29e-054599310GSM777037_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500

LAMA1 LAMA2 SVEP1 TGM2 GLI1 LTBP4

6.43e-05156936gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#5

CACNA1A TCF7L2 GPR50 PCLO LAMB2 DLL1 SCUBE1 TULP4 MEGF9 SEMA4A LTBP4 PLPPR2

8.32e-057329312Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K5
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

PDE3A LAMA1 LAMA2 SVEP1 TGM2 IGF2R GLI1 LTBP4

1.15e-04336938gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000

PDE3A LAMA1 LAMA2 DENND2B SVEP1 TGM2 SCUBE1 FBN2 IGF2R GLI1 LTBP4 NOTCH2

1.39e-047739312gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

HSPG2 LAMA2 LAMB2 HTRA3 DENND2B SVEP1 TGM2 THBS1 LTBP4

1.46e-04445939GSM777043_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_2500_k-means-cluster#3

ZXDC GPR50 LAMB2 DLL1 SCUBE1 TULP4 UHMK1 SEMA4A PLPPR2

1.51e-04447939Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_2500_K3
CoexpressionAtlasStromal Cells, St.31-38-44-.SLN, CD45- gp38- CD31- CD44-, Lymph Node, avg-2

HSPG2 PDE3A LAMA2 LAMB2 DENND2B SVEP1 TGM2 THBS1 LTBP4

1.67e-04453939GSM777067_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500

LAMA1 LAMA2 SVEP1 SCUBE1 FBN2 GLI1 LTBP4 NOTCH2

1.70e-04356938gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlasStromal Cells, FRC.SLN, gp38+ CD31- CD140a+, Lymph Node, avg-4

HSPG2 PDE3A LAMB2 SLC15A3 DENND2B SVEP1 TGM2 THBS1 LTBP4

1.72e-04455939GSM777055_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

GPR50 WDR81 DLL1 SCUBE1 SNRNP40 NOTCH1

2.24e-04196936Facebase_RNAseq_e10.5_Neural Epithelium Overlying Medial Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_500_k-means-cluster#4

CACNA1A PCLO DLL1 TULP4 PLPPR2

2.59e-04129935Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_500_K4
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000

CACNA1A PDE3A PCLO ADGRB2 LAMA2 DLL1 HIVEP3 THBS1 TULP4 LTBP3 SEMA4A LTBP4 PLPPR2

3.14e-049739313Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_top-relative-expression-ranked_500

LAMA1 DLL1 FBN2 SCUBE3 HABP2 RSPO1 NOTCH1 NOTCH2

3.61e-04398938gudmap_kidney_P4_CapMesRenVes_Crym_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

CACNA1A TCF7L2 GPR50 PCLO LAMA1 SLC15A3 DLL1 SCUBE1 USF3 UHMK1 SCUBE3 ZNHIT2 RSPO1

3.67e-049899313Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5

CACNA1A GPR50 PCLO LAMB2 THBS1 TULP4 MEGF9 SEMA4A LTBP4 RSPO1 PLPPR2

4.01e-047439311Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlasJC_hmvEC_top-relative-expression-ranked_500_k-means-cluster#1

HSPG2 VWF BCL6B TGM2 THBS1 NOTCH4

4.06e-04219936JC_hmvEC_500_K1
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#2

CACNA1A GPR50 PCLO LAMB2 DLL1 THBS1 TULP4 MEGF9 SEMA4A LTBP4 PLPPR2

4.20e-047479311Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K2
CoexpressionAtlaskidney_P2_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_500

THBS1 MEGF9 RSPO1

4.41e-0434933gudmap_kidney_P2_CapMes_Crym_k2_500
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4

VWF ADGRB2 LAMA2 HTRA3 SLC15A3 SVEP1 THBS1 FBN2 GLI1 LTBP3 LTBP4 RSPO1 PLPPR2 HR

4.57e-0411489314facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#3

CACNA1A TCF7L2 PCLO WDR81 LAMB2 DLL1 SCUBE1 TULP4 SEMA4A LTBP4 RSPO1 PLPPR2

5.16e-048939312Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K3
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5

CACNA1A GPR50 PCLO LAMB2 THBS1 TULP4 MEGF9 SEMA4A LTBP4 PLPPR2

6.10e-046589310Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K5
CoexpressionAtlasFacebaseRNAseq_e9.5_Mandibular Arch_top-relative-expression-ranked_1000_k-means-cluster#5

GPR50 WDR81 UHMK1 SNRNP40

6.89e-0491934Facebase_RNAseq_e9.5_Mandibular Arch_1000_K5
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

LAMA1 LAMA2 TTK DENND2B SVEP1 TGM2 THBS1 SCUBE1 GLI1 LTBP4 NOTCH2

6.90e-047939311gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

PDE3A LAMA1 SVEP1 VOPP1 SCUBE1 FBN2 IGF2R

7.02e-04337937gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_k-means-cluster#4_top-relative-expression-ranked_500

GPR50 FBN2 MEGF9 SPOCK3 TENM1 MEGF10

7.64e-04247936gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_500_k4
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#2

TCF7L2 GPR50 DLL1 SCUBE1 SEMA4A LTBP4

7.80e-04248936Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle F_emap-6706_k-means-cluster#3_top-relative-expression-ranked_500

GPR50 FBN2 MEGF9 SPOCK3 TENM1 MEGF10

7.97e-04249936gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle F_500_k3
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#2

CACNA1A GPR50 SEMA4A LTBP4 RSPO1 PLPPR2

7.97e-04249936Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K2
CoexpressionAtlaskidney_P4_CapMesRenVes_Crym_k-means-cluster#3_top-relative-expression-ranked_500

LAMA1 DLL1 FBN2 SCUBE3 NOTCH1

7.99e-04165935gudmap_kidney_P4_CapMesRenVes_Crym_k3_500
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#4_top-relative-expression-ranked_200

LAMA1 DLL1 SCUBE3

8.25e-0442933gudmap_developingKidney_e15.5_S-shaped body_200_k4
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#5

CACNA1A GPR50 PCLO LAMB2 THBS1 TULP4 MEGF9 SEMA4A LTBP4 PLPPR2

8.58e-046889310Facebase_RNAseq_e10.5_Mandibular Arch_2500_K5
CoexpressionAtlasStromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3

HSPG2 LAMA2 THBS1 LTBP4

8.75e-0497934GSM777043_100
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

HSPG2 PDE3A VWF LYPD2 TGM2 FBN2 LTBP3 LTBP4

5.02e-0917697852af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HSPG2 PDE3A VWF LYPD2 TGM2 FBN2 LTBP3

1.33e-071799778c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 HTRA3 SVEP1 FBN2 GLI1 LTBP4 MEGF10

1.67e-07185977785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 HTRA3 SVEP1 FBN2 GLI1 LTBP4 MEGF10

1.67e-0718597797a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 HTRA3 SVEP1 FBN2 GLI1 LTBP4 RSPO1

1.79e-071879774e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 HTRA3 SVEP1 FBN2 GLI1 LTBP4 RSPO1

1.79e-07187977d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 HTRA3 SVEP1 FBN2 GLI1 LTBP4 RSPO1

1.79e-07187977827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HSPG2 VWF LYPD2 BCL6B TGM2 NOTCH1 NOTCH4

1.86e-07188977366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

WDR81 LAMA2 DLL1 BCL6B GLI1 LTBP3 NOTCH4

1.86e-07188977c90669b51e1902fe7726555290c91c92a911df83
ToppCellE18.5-samps-Mesenchymal|E18.5-samps / Age Group, Lineage, Cell class and subclass

TCF7L2 LAMA2 SVEP1 THBS1 IGF2R LTBP4 NOTCH2

1.93e-071899770c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 HTRA3 SVEP1 GLI1 LTBP3 LTBP4

2.15e-07192977a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 HTRA3 SVEP1 THBS1 FBN2 LTBP4

2.15e-071929778937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 HTRA3 SVEP1 GLI1 LTBP3 LTBP4

2.15e-07192977eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 HTRA3 SVEP1 THBS1 FBN2 LTBP4

2.15e-07192977e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCellfacs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 HTRA3 SVEP1 THBS1 FBN2 LTBP4

2.15e-07192977ac1477433704573f95111eee6263b93668d2845e
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 LAMB2 HTRA3 GLI1 LTBP3 LTBP4

2.22e-07193977858a186804b36d45957238d3d3eed2768b961641
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 LAMB2 HTRA3 GLI1 LTBP3 LTBP4

2.22e-071939777865e7ec0a288249540d4cba94ae01c93e1b617c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 PDE3A VWF BCL6B TGM2 LTBP4 NOTCH4

2.22e-071939770b328f725f6feba263783eaca60c142e80df90f3
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 LAMB2 HTRA3 SVEP1 THBS1 LTBP3

2.22e-0719397745b5cab4dfeb0ed3b13631db5963740a792b810f
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_progenitor|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 LAMB2 HTRA3 SVEP1 LTBP3 LTBP4

2.38e-0719597769a29d03e664b72f32d41876510c62345c3aed31
ToppCellfacs-GAT-Fat-3m-Mesenchymal|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 LAMB2 HTRA3 SVEP1 LTBP3 LTBP4

2.38e-071959771cffae2b08dbfa1c633ce24023e89b66d28b5431
ToppCellfacs-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 LAMA2 LAMB2 THBS1 LTBP3 LTBP4 NOTCH2

2.38e-07195977c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCellfacs-GAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 LAMB2 HTRA3 SVEP1 LTBP3 LTBP4

2.38e-071959779cef6f18664518060af7c192310dddce6d70345a
ToppCellfacs-Lung-nan|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 LAMB2 HTRA3 THBS1 LTBP3 LTBP4

2.47e-07196977b05f77f3990b662682ffeaf0e4c2fb190e0a6e65
ToppCellfacs-Lung-nan-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 LAMB2 HTRA3 THBS1 LTBP3 LTBP4

2.47e-07196977787c6cd92035e0b1108c2c086c42a229016e476b
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG|World / Primary Cells by Cluster

LAMA1 LAMB2 DENND2B NOTCH1 MEGF10 NOTCH2 CRB2

2.55e-0719797761749ccafeb938c310cff1de5ff924a1c794325a
ToppCellNon-neuronal-Non-dividing-Radial_Glia-tRG-25|World / Primary Cells by Cluster

LAMA1 LAMB2 DENND2B NOTCH1 MEGF10 NOTCH2 CRB2

2.55e-071979779d4ffa3680f92c91d0a081f9a8ec5ebfec6bdcf6
ToppCelldroplet-Pancreas-Exocrine-18m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LCE6A LAMB2 TGM2 HABP2 NOTCH2

1.91e-0616997653690d6f9712b54aa99a0408aae930d64ae478e5
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SVEP1 HIVEP3 THBS1 FBN2 WDR90 MEGF10

1.98e-06170976ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCellfacs-Lung-nan-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A VWF LAMB2 DLL1 HABP2 LTBP4

1.98e-061709768e1f757ed62218c0fb6525f49d142dd2cd29acf9
ToppCellfacs-Lung-nan-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE3A VWF LAMB2 DLL1 HABP2 LTBP4

1.98e-0617097667d7e1da3ebd2d14cb2e67799e94d655027ed5c4
ToppCellChildren_(3_yrs)-Endothelial-endothelial_cell_of_artery-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

HSPG2 PDE3A VWF BCL6B BRINP2 NOTCH4

2.05e-061719761597459c971d6befa991d59dc66b41b6a522f797
ToppCelldroplet-Pancreas-Exocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LCE6A LAMB2 TGM2 HABP2 NOTCH2

2.05e-0617197692ac4cc3d54da2ea8e202aa59c78e8875356649e
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HSPG2 VWF LYPD2 BCL6B TGM2 NOTCH4

2.12e-06172976de9b11ab109d04937186c09772cec9105a935f95
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

HSPG2 VWF LYPD2 BCL6B TGM2 NOTCH4

2.19e-061739763a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 ERBB3 LAMA2 SLC15A3 MEGF9 MEGF10

2.76e-06180976b294f9db1e2ff51c94cde64fae4c2b057c0030a1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN PCLO LAMA1 SSPOP FBN2 TENM1

3.13e-061849762cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN PCLO LAMA1 SSPOP FBN2 TENM1

3.13e-06184976ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZAN PCLO LAMA1 SSPOP FBN2 TENM1

3.13e-061849762b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 HTRA3 SVEP1 GLI1 LTBP4 RSPO1

3.13e-061849763bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCelldroplet-Kidney-nan-21m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 HTRA3 SVEP1 GLI1 LTBP4 RSPO1

3.23e-0618597633cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMA2 CSMD2 SVEP1 THBS1 GLI1 TENM1

3.23e-061859769faa35ceb89ccd2979072286f063687c9f846ce3
ToppCelldroplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 HTRA3 SVEP1 GLI1 LTBP4 RSPO1

3.23e-061859769954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 HTRA3 SVEP1 FBN2 GLI1 LTBP4

3.33e-0618697694d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_venous_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HSPG2 VWF LYPD2 DLL1 BCL6B TGM2

3.43e-0618797603de3c2df31bca0dc4e3718bada708d8fe8b69b9
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 LCE6A LAMB2 TGM2 HABP2 NOTCH2

3.54e-06188976842982de2197770f999a70083ed9fca40ac22d79
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERBB3 LCE6A LAMB2 TGM2 HABP2 NOTCH2

3.54e-06188976a0815eaf68eedd6e5ec4af520df80a6ab4eb0864
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

B4GALT2 HSPG2 LAMA2 HTRA3 LTBP3 MEGF10

3.54e-06188976bba6b273bd47dd0e27fde914e9e6fc9d76fd5176
ToppCelldroplet-Lung-immune-endo-depleted|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 HTRA3 SVEP1 LTBP3 LTBP4

3.65e-06189976c3fb363bb0156ffb3367c200f548faebda64ab4a
ToppCelldroplet-Lung-immune-endo-depleted-3m|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 HTRA3 SVEP1 LTBP3 LTBP4

3.65e-061899762a2953f6b1b7d070d739dcaf7285fce6e097d9e4
ToppCelldroplet-Lung-3m|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 LAMA2 HTRA3 SVEP1 LTBP3 LTBP4

3.65e-061899765a636e952da9b1fd26aa17f7b129054f2da322b5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 PDE3A VWF TGM2 LTBP4 NOTCH4

3.76e-06190976bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 DENND2B SVEP1 THBS1 SEMA4A NOTCH2

3.76e-061909761121eb607a984c59fbffe7220837fc178745aa55
ToppCellfacs-Diaphragm-Limb_Muscle-24m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TCF7L2 LAMB2 HTRA3 SVEP1 THBS1 LTBP4

3.76e-06190976d13fd234caa3fc69d8a59bc0060cdacdf716ee55
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 DENND2B SVEP1 THBS1 SEMA4A NOTCH2

3.76e-06190976048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 VWF TNFRSF6B BCL6B TGM2 NOTCH4

3.76e-0619097606bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 HTRA3 SVEP1 LTBP3 LTBP4

3.76e-061909769cd147a174017ebda23cc47b6d4552d898acd092
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal|E16.5-samps / Age Group, Lineage, Cell class and subclass

HTRA3 SVEP1 HIVEP3 IGF2R LTBP4 NOTCH2

3.88e-061919763379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCellP07-Endothelial-large_vessel_endothelial_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PDE3A VWF DLL1 TGM2 LTBP4 NOTCH1

3.88e-06191976d162917816dd2e4767c97447c1cddae9397713ab
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 LAMA2 HTRA3 SVEP1 GLI1 LTBP4

4.00e-06192976c3707243c5590d852c9f28429c96f50a1fa6b0dc
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 LAMA2 LAMB2 HTRA3 GLI1 LTBP4

4.00e-061929760e7e55505bd5454d7cf952a63fdcb46ec76f1973
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 LAMA2 HTRA3 SVEP1 GLI1 LTBP4

4.00e-061929767b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 LAMA2 HTRA3 SVEP1 LTBP3 LTBP4

4.00e-0619297632acd89617934016cd135d2cc797e8e79ae1b37f
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 LAMA2 HTRA3 SVEP1 GLI1 LTBP4

4.00e-06192976f9fb24457999dc9e751a099d7f995543b9330ad4
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 HTRA3 SVEP1 LTBP3 LTBP4 RSPO1

4.12e-06193976ebd090d7801480b3cee45caac3d30cc991836769
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 HTRA3 SVEP1 LTBP3 LTBP4 RSPO1

4.12e-0619397622c58032e58730715224d7934968ce92d150b0e8
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 LAMA2 HTRA3 SVEP1 GLI1 LTBP4

4.12e-061939769d0b966d13cbce97beb43de6dc77f006c363a181
ToppCelldroplet-Limb_Muscle-nan-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 HTRA3 SVEP1 THBS1 LTBP3

4.12e-0619397649600db68ed65cafc67bd45a285b364e4f5f88af
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSPG2 LAMA2 HTRA3 SVEP1 LTBP3 LTBP4

4.12e-06193976d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 LAMA2 LAMB2 HTRA3 GLI1 LTBP4

4.12e-06193976025836c5c5a711e477c326559e618e47cae42d11
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA2 HTRA3 SVEP1 LTBP3 LTBP4 RSPO1

4.12e-06193976573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

LAMA2 HTRA3 SVEP1 THBS1 LTBP4 NOTCH2

4.24e-06194976d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellfacs-Heart-LA-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VWF DUSP3 BCL6B TGM2 NOTCH1 NOTCH4

4.24e-0619497633cc4f1d716cb71d54cdedbe9bbdc0d7b17c4777
ToppCellPCW_05-06-Endothelial-Endothelial_mature|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HSPG2 VWF LYPD2 BCL6B TGM2 NOTCH4

4.37e-0619597654fde2cfa51ab3a2d48d2426494ca6f0ce77f725
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A LAMA2 DENND2B SVEP1 THBS1 LTBP4

4.37e-06195976cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A LAMA2 DENND2B SVEP1 THBS1 LTBP4

4.37e-06195976783bfa8110161cbd6def50ce849cae676c39c458
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PDE3A TCF7L2 LAMA2 SVEP1 LTBP4 NOTCH2

4.50e-06196976dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 HTRA3 SVEP1 GLI1 LTBP4 RSPO1

4.50e-06196976e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 HTRA3 SVEP1 GLI1 LTBP4 RSPO1

4.50e-0619697682fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 VWF BCL6B LTBP4 NOTCH1 NOTCH4

4.50e-06196976a20a56d8997d6db2a10046c8801c619a379de83c
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMA2 HTRA3 SVEP1 GLI1 LTBP4 RSPO1

4.50e-0619697685e5046f774537684e1443c0fc147d562b7068d0
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 VWF TNFRSF6B BCL6B TGM2 NOTCH4

4.50e-06196976ed818de15f84f7f28bd06fd69d7876710da232a0
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 VWF TNFRSF6B BCL6B TGM2 NOTCH4

4.63e-0619797662c0a90869431e582bb7bb329e0b0cc59123d3d1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A LAMA2 DENND2B SVEP1 THBS1 LTBP4

4.63e-0619797609946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCellTracheal-10x5prime-Stromal-Peri/Epineurial_|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA2 SCUBE1 FBN2 GLI1 SCUBE3 LTBP4

4.63e-061979762cb1f557ce1400398975de94638126b4522567f3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PDE3A LAMA2 DENND2B SVEP1 THBS1 SEMA4A

4.63e-061979769b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_immature-Tip-like|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 VWF TNFRSF6B BCL6B TGM2 NOTCH4

4.63e-0619797616f0eb047df9d702518f82ee99c6e7dc1350b2fb
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

PDE3A LAMA2 CSMD2 SVEP1 THBS1 DIP2C

4.63e-06197976fb847f2277609c31fffcdf49517243ce0684facf
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMA2 HTRA3 SVEP1 SCUBE1 GLI1 RSPO1

4.77e-06198976300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 DENND2B SVEP1 THBS1 SEMA4A NOTCH2

4.77e-06198976a860246bcea847249a78fd2e86ed8e04371060db
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

HSPG2 PDE3A VWF TGM2 BRINP2 NOTCH4

4.77e-0619897688b4662be9cc933a402c52673fa5e00fa979c0db
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-Venous_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

HSPG2 VWF LYPD2 DLL1 TGM2 SCUBE3

4.91e-0619997670e05d7c0c68c28754ce0e72434b205aed6287ae
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 VWF BCL6B TGM2 LTBP4 NOTCH4

4.91e-06199976f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCelldistal-Endothelial-Artery|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSPG2 VWF LYPD2 TGM2 LTBP4 NOTCH4

4.91e-06199976b6e9aaac047d4b64b9d97f5e174e89a424d8b36d
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 VWF TNFRSF6B BCL6B TGM2 NOTCH4

4.91e-06199976236b1417ed0875e98c6ec1ec714003bfce438d65
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 VWF BCL6B TGM2 LTBP4 NOTCH4

4.91e-0619997633f1669eeb701986b4dec409efdb6c06c3c41c2b
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 VWF TNFRSF6B BCL6B TGM2 NOTCH4

4.91e-061999760602e2b2aa56d106da63bd342a38bef437b4d496
ToppCelldistal-Endothelial-Artery-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

HSPG2 VWF LYPD2 TGM2 LTBP4 NOTCH4

4.91e-061999763788f3218356aaaa10684e48d63757037f8a3a3c
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

HSPG2 VWF LYPD2 BCL6B TGM2 NOTCH4

4.91e-06199976243b7c72f83c12a34d8ea300fca63b04216268a4
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HSPG2 VWF TNFRSF6B BCL6B TGM2 NOTCH4

5.05e-0620097686ec951234015ced7126b016199e5869a0f22478
DrugAC1L1G72

LAMB4 LAMA1 LAMA2 LAMB2

8.42e-0811934CID000003553
DrugLMWH

HSPG2 LAMB4 ERBB3 VWF LAMA1 WDR81 LAMA2 LAMB2 CFHR5 THBS1 SPOCK3 HABP2 PLG RSPO1

4.89e-076639314CID000000772
DrugRgd Peptide

LAMB4 VWF ADGRB2 LAMB2 THBS1 FBN2 PLG RSPO1 FBN3

5.95e-07239939CID000104802
Drugpyrachlostrobin

HSPG2 LAMB2 DENND2B SVEP1 TGM2 THBS1 SCUBE1 SPOCK3 LTBP3 SEMA4A KLHDC7A NOTCH1 MEGF10 NOTCH2 CRB2

9.74e-078119315ctd:C513428
Drug2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine

LAMB4 LAMA1 LAMA2 LAMB2 TGM2 THBS1

1.16e-0683936CID011968896
Drugkalinin

HSPG2 LAMB4 LAMA1 LAMA2 LAMB2

3.02e-0655935CID000032518
DrugLG 5

LAMB4 ERBB3 LAMA1 LAMA2 LAMB2

4.67e-0660935CID011840957
DrugAC1L1B58

LAMB4 LAMA1 LAMA2 LAMB2

5.73e-0629934CID000001288
Drugdysprosium

LAMB4 LAMA1 LAMA2 LAMB2 PLG

1.32e-0574935CID000023912
DrugLinuron

CACNA1A ERBB3 DLL1 IGF2R NOTCH2 NOTCH4

1.43e-05128936ctd:D008044
Drugenzacamene

CACNA1A ERBB3 IGF2R NOTCH2 NOTCH4 HR

1.50e-05129936ctd:C038939
Drug2-amino-5-methylpyridine

LAMB4 ERBB3 LAMA1 LAMA2 LAMB2

1.60e-0577935CID000015348
DrugCalcort

LAMB4 LAMA1 LAMA2 LAMB2

1.73e-0538934CID000026709
DrugNimodipine [66085-59-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A

TNFRSF6B ZFPL1 TGM2 SEMA4A LTBP4 NOTCH2 HR

1.76e-051999375421_DN
Drugoctylmethoxycinnamate

CACNA1A ERBB3 IGF2R NOTCH2 NOTCH4 HR

2.29e-05139936ctd:C118580
DrugRgdf peptide

VWF WDR81 PLG

2.32e-0514933CID003080994
DrugNSC 714187

LAMB4 ERBB3 LAMA1 LAMA2 LAMB2

2.59e-0585935CID005288693
Drugbutylparaben

CACNA1A ERBB3 IGF2R NOTCH2 NOTCH4 HR

4.54e-05157936ctd:C038091
DrugAC1MHG1S

VWF PLG

4.94e-053932CID003025825
Drugsulfate

HSPG2 LAMB4 ERBB3 VWF TNFRSF14 LAMA1 LAMA2 LAMB2 DLL1 TGM2 THBS1 IGF2R SPOCK3 HABP2 PLG RSPO1

6.38e-0512929316CID000001117
DiseaseMalignant neoplasm of breast

ERBB3 VWF LAMA2 CFHR5 DLL1 TGM2 THBS1 GLI1 TENM1 DIP2C KLHDC7A ZNHIT2 NOTCH1 NOTCH2 NOTCH4

6.25e-0710748815C0006142
Diseaseintestinal cancer (implicated_via_orthology)

ERBB3 SOX14 NOTCH1 NOTCH2

2.49e-0632884DOID:10155 (implicated_via_orthology)
DiseaseNeoplasm of uncertain or unknown behavior of bladder

ERBB3 NOTCH1 NOTCH2

1.14e-0515883C0496930
DiseaseBenign neoplasm of bladder

ERBB3 NOTCH1 NOTCH2

1.14e-0515883C0154017
DiseaseCarcinoma in situ of bladder

ERBB3 NOTCH1 NOTCH2

1.14e-0515883C0154091
DiseaseSchizophrenia

ERBB3 TCF7L2 GPR50 LAMA1 LAMA2 CSMD2 TGM2 THBS1 UHMK1 PLG MEGF10 NOTCH4

1.22e-058838812C0036341
DiseaseCarcinoma of bladder

ERBB3 NOTCH1 NOTCH2

2.02e-0518883C0699885
Diseaseconnective tissue disease (implicated_via_orthology)

FBN2 FBN3

2.63e-053882DOID:65 (implicated_via_orthology)
DiseaseMalignant neoplasm of skin

ERBB3 NOTCH1 NOTCH2 NOTCH4

2.97e-0559884C0007114
DiseaseSkin Neoplasms

ERBB3 NOTCH1 NOTCH2 NOTCH4

2.97e-0559884C0037286
Diseaseosteonecrosis (is_marker_for)

VWF PLG

5.26e-054882DOID:10159 (is_marker_for)
DiseaseBladder Neoplasm

ERBB3 LAMA2 GLI1 NOTCH1 NOTCH2

6.39e-05140885C0005695
DiseaseMalignant neoplasm of urinary bladder

ERBB3 LAMA2 GLI1 NOTCH1 NOTCH2

6.61e-05141885C0005684
DiseaseGlioblastoma

TGM2 LTBP4 NOTCH1 NOTCH2

9.35e-0579884C0017636
DiseaseGiant Cell Glioblastoma

TGM2 LTBP4 NOTCH1 NOTCH2

1.19e-0484884C0334588
Diseaseretinal vasculature measurement

HSPG2 PDE3A TCF7L2 LAMA2 HTRA3 DENND2B LTBP3 CRB2

1.59e-04517888EFO_0010554
DiseaseMammary Carcinoma, Human

ERBB3 DLL1 TGM2 THBS1 KLHDC7A NOTCH1 NOTCH2 NOTCH4

1.76e-04525888C4704874
DiseaseMammary Neoplasms, Human

ERBB3 DLL1 TGM2 THBS1 KLHDC7A NOTCH1 NOTCH2 NOTCH4

1.76e-04525888C1257931
DiseaseMammary Neoplasms

ERBB3 DLL1 TGM2 THBS1 KLHDC7A NOTCH1 NOTCH2 NOTCH4

1.81e-04527888C1458155
Diseaseadenocarcinoma (implicated_via_orthology)

NOTCH1 NOTCH2

1.83e-047882DOID:299 (implicated_via_orthology)
Diseasecentral nervous system cancer (implicated_via_orthology)

NOTCH1 NOTCH2

1.83e-047882DOID:3620 (implicated_via_orthology)
DiseaseBreast Carcinoma

ERBB3 DLL1 TGM2 THBS1 KLHDC7A NOTCH1 NOTCH2 NOTCH4

2.08e-04538888C0678222
DiseaseScoliosis, unspecified

DLL1 NOTCH1

2.43e-048882C0036439
DiseaseColorectal Carcinoma

TCF7L2 LAMA1 HIVEP3 TGM2 FBN2 TENM1 DIP2C PLPPR2 HR

2.49e-04702889C0009402
Diseaseclinical treatment

TCF7L2 PLG NOTCH4

2.52e-0441883EFO_0007056
Diseasehemangiopericytoma (is_marker_for)

NOTCH1 NOTCH4

3.12e-049882DOID:264 (is_marker_for)
DiseaseGlioblastoma Multiforme

TGM2 LTBP4 NOTCH1 NOTCH2

3.47e-04111884C1621958
Diseasepulmonary fibrosis (biomarker_via_orthology)

VWF HABP2 NOTCH1

4.54e-0450883DOID:3770 (biomarker_via_orthology)
Diseasecortical thickness

HSPG2 ERBB3 TCF7L2 LAMA1 LAMA2 THBS1 SCUBE1 FBN2 MEGF9 PKD1 CRB2

4.71e-0411138811EFO_0004840
Diseasevelopharyngeal dysfunction

LAMA1 SCUBE1 SPOCK3 PLG

4.96e-04122884EFO_0009336
DiseaseFamilial thoracic aortic aneurysm and aortic dissection

FBN2 PKD1 NOTCH1

5.39e-0453883C4707243
DiseaseBipolar Disorder

CACNA1A ERBB3 TCF7L2 GPR50 PCLO TGM2 NOTCH4

5.68e-04477887C0005586
Diseasecortical surface area measurement

CACNA1A ERBB3 PDE3A TCF7L2 ZAN LAMA2 SVEP1 THBS1 SCUBE1 FBN2 PKD1 FBN3

6.39e-0413458812EFO_0010736
DiseaseConnective Tissue Diseases

PKD1 NOTCH1

6.71e-0413882C0009782
DiseasePR interval

HSPG2 PDE3A LAMB2 HIVEP3 TGM2 THBS1 FBN2

7.06e-04495887EFO_0004462
Diseaseintraocular pressure measurement

TCF7L2 PCLO ADGRB2 HIVEP3 FBN2 LTBP3 RSPO1

8.31e-04509887EFO_0004695
Diseasebreast carcinoma

TCF7L2 LAMB2 HIVEP3 FBN2 KMT5B HABP2 SEMA4A KLHDC7A PLG NOTCH2

9.11e-0410198810EFO_0000305
DiseaseFEV/FEC ratio

HSPG2 ERBB3 PDE3A MYRFL DENND2B HIVEP3 SCUBE3 LTBP3 LTBP4 PLPPR2 CRB2

1.06e-0312288811EFO_0004713
DiseaseCraniofacial Abnormalities

HSPG2 GSC LTBP3 NOTCH1

1.24e-03156884C0376634
Diseasecarotid artery disease (is_marker_for)

HSPG2 VWF

1.45e-0319882DOID:3407 (is_marker_for)
Diseaseeosinophil count

ERBB3 DUSP3 MKRN1 TNFRSF14 SVEP1 HIVEP3 HABP2 LTBP3 LTBP4 NOTCH1 NOTCH2 NOTCH4

1.53e-0314888812EFO_0004842
Diseasecoagulation factor measurement

VWF CFHR5

1.61e-0320882EFO_0004634
Diseaseage of onset of asthma

ERBB3 SCUBE3 LTBP3

1.72e-0379883OBA_2001001
Diseasegestational diabetes

TCF7L2 LTBP4

2.14e-0323882EFO_0004593
DiseaseCarcinoma, Pancreatic Ductal

NOTCH1 NOTCH4

2.33e-0324882C0887833
DiseaseCerebral Astrocytoma

NOTCH1 NOTCH2

2.52e-0325882C0750935
DiseaseIntracranial Astrocytoma

NOTCH1 NOTCH2

2.52e-0325882C0750936
DiseaseAstrocytoma

NOTCH1 NOTCH2

2.52e-0325882C0004114
DiseaseGrade I Astrocytoma

NOTCH1 NOTCH2

2.52e-0325882C1704230
DiseaseSubependymal Giant Cell Astrocytoma

NOTCH1 NOTCH2

2.52e-0325882C0205768
DiseaseMixed oligoastrocytoma

NOTCH1 NOTCH2

2.52e-0325882C0547065
DiseasePilocytic Astrocytoma

NOTCH1 NOTCH2

2.52e-0325882C0334583
DiseaseJuvenile Pilocytic Astrocytoma

NOTCH1 NOTCH2

2.52e-0325882C0280783
DiseaseDiffuse Astrocytoma

NOTCH1 NOTCH2

2.52e-0325882C0280785
DiseaseChildhood Cerebral Astrocytoma

NOTCH1 NOTCH2

2.52e-0325882C0338070
Diseaserefractive error, age at onset, Myopia

PDE3A TCF7L2 LAMA2 HIVEP3

2.70e-03193884EFO_0004847, HP_0000545, MONDO_0004892
Diseasebrain cancer (implicated_via_orthology)

NOTCH1 NOTCH2

2.73e-0326882DOID:1319 (implicated_via_orthology)
DiseaseGemistocytic astrocytoma

NOTCH1 NOTCH2

2.73e-0326882C0334581
DiseaseProtoplasmic astrocytoma

NOTCH1 NOTCH2

2.73e-0326882C0334580
DiseaseFibrillary Astrocytoma

NOTCH1 NOTCH2

2.73e-0326882C0334582
DiseaseNeurodevelopmental Disorders

TCF7L2 HIVEP3 KMT5B

2.74e-0393883C1535926
Diseasealcohol use disorder (implicated_via_orthology)

ERBB3 NOTCH1 NOTCH2 HR

2.80e-03195884DOID:1574 (implicated_via_orthology)
DiseaseAnaplastic astrocytoma

NOTCH1 NOTCH2

2.94e-0327882C0334579

Protein segments in the cluster

PeptideGeneStartEntry
CVSSPYGTLCSGPLR

ADGRB2

336

O60241
EPARTCPNGTKCQPY

CACNA1A

276

O00555
DSGACVPRCPQPLVY

ERBB3

251

P21860
GGRYTPPDCTPAQTV

B4GALT2

131

O60909
PRPVCTAPCGGQYVG

CSMD2

1611

Q7Z408
ACSYLGPRPQRTPCS

ASB16-AS1

101

Q495Z4
RCSPRGDCLNVPGSY

FBN3

1331

Q75N90
GRRGPCSYSCANTPG

FBN3

2616

Q75N90
PGRGLPQLPSSCYSV

DENND2B

296

P78524
PGLPETSSCVCPGYI

BBS12

321

Q6ZW61
SNRYCGGPGPPITDC

DYRK1B

486

Q9Y463
QPYCGRTVPSCTEAP

MKRN4P

211

Q13434
SLYVPCAPSPCVNGG

NOTCH2NLA

181

Q7Z3S9
LEVEQCSCPPGYRGP

HSPG2

1121

P98160
CGDPSTYRVTFPVCP

RIMBP3B

1201

A6NNM3
CGDPSTYRVTFPVCP

RIMBP3C

1201

A6NJZ7
TPCPLGTYGINCSSR

MEGF10

441

Q96KG7
LYVPCAPSPCVNGGT

NOTCH2NLB

221

P0DPK3
LYVPCAPSPCVNGGT

NOTCH2

221

Q04721
TGPNCERPYVPCSPS

NOTCH1

211

P46531
ERPYVPCSPSPCQNG

NOTCH1

216

P46531
YTCGPMEPRGCATQP

CRB2

61

Q5IJ48
LCVPQGPDPTGFRCY

CRB2

81

Q5IJ48
PCTVLYEGPVRGLCP

ASPDH

171

A6ND91
VPVSYTDCAPSPVGC

KMT5B

661

Q4FZB7
AVPTPYGCIGCKLPQ

GPR50

6

Q13585
SPEPPVTQRGCCSSY

HR

316

O43593
PPGPQYCVGSVLRSS

PCLO

3071

Q9Y6V0
PPVICSSCGRPYSQG

PDE3A

581

Q14432
PTESGKYPCGESCPR

FAM47B

176

Q8NA70
SCSPPQVKGACYPTL

MYRFL

61

Q96LU7
IGCSYPQQPLCHSPG

MYRFL

141

Q96LU7
SSPPPEYVCNCSVVG

MEGF9

196

Q9H1U4
APDVPGCSRGSCYPA

LAMB2

36

P55268
TPPPISSYGEPCCLR

GLI1

6

P08151
SSYGEPCCLRPLPSQ

GLI1

11

P08151
CERCAPGYTGSPGNP

LAMA2

1506

P24043
SLYVPCAPSPCVNGG

NOTCH2NLC

181

P0DPK4
PALRCYVCPEPTGVS

LYPD2

21

Q6UXB3
VCRPNYTALGCLPPS

PLPPR2

161

Q96GM1
QPPPGLVYPCGACRS

PYGO2

321

Q9BRQ0
PYTGPSCSQVVPVCR

HABP2

141

Q14520
VSRCPSPRCPGGYVP

HTRA3

31

P83110
HTGEKPYPCPTCGTR

BCL6B

406

Q8N143
PGYTGRNCSAPVSRC

DLL1

471

O00548
GCLYAGCVPITVRPP

DIP2C

1046

Q9Y2E4
RCVESTAYCGPPPSI

CFHR5

441

Q9BXR6
LNNPGSYRCVCPPGH

LTBP3

371

Q9NS15
SYRCVCPPGHSLGPS

LTBP3

376

Q9NS15
PGSYRCTPACDPGYQ

LTBP4

1026

Q8N2S1
GCYSLPSQPCNEVTP

DUSP3

21

P51452
APQGCSCENPRGPYV

KLHDC7A

91

Q5VTJ3
LGAQQCSCVPTPPGY

GSC

106

P56915
FYGNPRISGAPCQPC

LAMB4

956

A4D0S4
QRSNPCLAPYSTPCG

LCE6A

21

A0A183
CRNTPGSYSCTCPPG

FBN2

826

P35556
GTYQPEPGRTGCFPC

SCUBE1

706

Q8IWY4
CQPCPRGTYQPEAGR

SCUBE3

706

Q8IX30
AGCPRSSPSPYCAPV

SLC15A3

146

Q8IY34
DRCTPIPGGPTISYT

PKD1

1586

P98161
QPYCGRTAPSCTEAP

MKRN1

176

Q9UHC7
PLNPVPGCNRYASAC

IGF2R

816

P11717
PGGQLYSDCVSLCPP

SSPOP

471

A2VEC9
NRTGLPCPEYTCPNG

SSPOP

1651

A2VEC9
SPCSVPCGGGYRNRT

SSPOP

3051

A2VEC9
LYPPGSTVVRPCENC

SSPOP

3151

A2VEC9
YTCPKGAPAQSCRPA

SAXO1

311

Q8IYX7
ATPRCYICDQPTGGI

RNF113B

286

Q8IZP6
CGDPSTYRVTFPVCP

RIMBP3

1201

Q9UFD9
YGNPTVPGESCVPCD

LAMA1

836

P25391
TYRGPETNPRPGSCS

SEMA4A

366

Q9H3S1
SCYPARRGPQLVCTG

SNRNP40

156

Q96DI7
QVGVCLPSCPPGYFD

RSPO1

71

Q2MKA7
SNCYISPLCQGSPDP

TENM1

826

Q9UKZ4
CSSPPQIRGCGASYP

SPATA31E1

536

Q6ZUB1
RCTTPPPSSGPTYQC

PLG

261

P00747
SQPYPVCEPLSCGSP

SVEP1

3111

Q4LDE5
PLTGSTLCLCQPGYS

NOTCH4

411

Q99466
PGSFNCLCPPGYTGS

NOTCH4

456

Q99466
ISAPCAHGGTCYPQP

NOTCH4

696

Q99466
PPSPCLYNGSCSETT

NOTCH4

1136

Q99466
PYDQSSCQGPIPCAL

BRINP2

446

Q9C0B6
CCYPQSRPTASAAGP

C10orf95

76

Q9H7T3
PQEKSEGTYCCGPVP

TGM2

361

P21980
PPALYTCSQCSGTGP

TULP4

1031

Q9NRJ4
QGSVACPPPPAYCNT

VOPP1

146

Q96AW1
TDPGYNCLPCPPRFT

THBS1

611

P07996
PPLLYCGTSSGQVCV

WDR90

1311

Q96KV7
STPGYRCPEPQCALA

ZXDC

171

Q2QGD7
TECPCVHSGKRYPPG

VWF

346

P04275
AEPVQGCPCNYRAPS

SPATA31D1

1451

Q6ZQQ2
CVRYIQGEGSCLSPP

TCF7L2

486

Q9NQB0
IRSHTGERPYPCGPC

HIVEP3

211

Q5T1R4
SAPSLPCPNGTTRCY

TEX101

151

Q9BY14
TQCGPSSAIEYNCPP

USF3

1846

Q68DE3
QCPVVYPSPVCGSDG

SPOCK3

141

Q9BQ16
PAGEVQPARYTCPRC

ZNHIT2

11

Q9UHR6
TVCVTGPAPCPTQTY

XP32

41

Q5T750
PPACQLSTPYGQPAC

TTK

476

P33981
TGTVCEPCPPGTYIA

TNFRSF14

71

Q92956
LYSRSPGQPIGSCSP

TARBP1

431

Q13395
THCPTGPPSKAYCRG

nan

131

Q96M66
SVYRVRCCGNPGSPP

UHMK1

36

Q8TAS1
PSPTNPGYVVPCNCT

SOX14

191

O95416
TQCPSYAREGPCPPR

WDR81

196

Q562E7
LPRNTAPAGYQCPSC

ZFPL1

86

O95159
CPVCQTSYQPGNLRP

TRIM6

56

Q9C030
GPNRTSYCRNPLCEP

TMEM39B

6

Q9GZU3
THSGEKPYPCPQCGR

ZNF764

336

Q96H86
SPTTCGPCPPRHYTQ

TNFRSF6B

66

O95407
TFCPMRCPPGSSYSP

ZAN

1806

Q9Y493