Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	monoatomic cation transmembrane transporter activity	SLC6A6 SLC9A5 SLC39A2 SLC9B2 CACNA1I SLC46A1 KCNK7 SLC39A5 SLC4A9 CHRNE CHRNG TMEM63A	3.37e-05	664	88	12	GO:0008324
GeneOntologyMolecularFunction	monoatomic ion transmembrane transporter activity	SLC6A6 SLC9A5 SLC39A2 SLC9B2 CACNA1I SLC46A1 KCNK7 SLC39A5 SLC4A9 CHRNE CHRNG TMEM63A	1.82e-04	793	88	12	GO:0015075
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC6A6 SLC9A5 SLCO2B1 SLC9B2 SLC46A1 SLC39A5 SLC4A9	3.34e-04	296	88	7	GO:0015291
GeneOntologyMolecularFunction	inorganic cation transmembrane transporter activity	SLC6A6 SLC9A5 SLC39A2 SLC9B2 CACNA1I SLC46A1 KCNK7 SLC39A5 SLC4A9 TMEM63A	4.33e-04	627	88	10	GO:0022890
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC6A6 SLC9A5 SLC39A2 SLCO2B1 SLC9B2 CACNA1I SLC46A1 KCNK7 SLC39A5 SLC4A9 CHRNE CHRNG TMEM63A SLC52A3	6.21e-04	1180	88	14	GO:0022857
GeneOntologyMolecularFunction	receptor ligand activity	CER1 CARTPT IL13 ADIPOQ WNT3 AGRP CHGB CTSG GDF11	6.81e-04	547	88	9	GO:0048018
GeneOntologyMolecularFunction	signaling receptor activator activity	CER1 CARTPT IL13 ADIPOQ WNT3 AGRP CHGB CTSG GDF11	7.45e-04	554	88	9	GO:0030546
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	VLDLR OR8D1 ADGRG3 CD4 NRXN3 OR5I1 UNC5C GPR152 OR1E2 TAAR5 FGFR4 TREML1 CHRNE CHRNG TMEM63A	7.88e-04	1353	88	15	GO:0004888
GeneOntologyMolecularFunction	metal cation:monoatomic cation antiporter activity	SLC9A5 SLC9B2 SLC4A9	8.99e-04	43	88	3	GO:0140828
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC6A6 SLC9A5 SLC9B2 CACNA1I SLC4A9	9.59e-04	171	88	5	GO:0015081
GeneOntologyMolecularFunction	metal ion transmembrane transporter activity	SLC6A6 SLC9A5 SLC39A2 SLC9B2 CACNA1I KCNK7 SLC39A5 SLC4A9	1.03e-03	465	88	8	GO:0046873
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC39A5 SLC4A9	1.45e-03	13	88	2	GO:0140410
GeneOntologyMolecularFunction	transporter activity	SLC6A6 SLC9A5 SLC39A2 SLCO2B1 SLC9B2 CACNA1I SLC46A1 KCNK7 SLC39A5 SLC4A9 CHRNE CHRNG TMEM63A SLC52A3	1.46e-03	1289	88	14	GO:0005215
GeneOntologyMolecularFunction	serine-type endopeptidase activity	RHBDL2 CTSC TPSG1 OVCH1 CTSG	1.53e-03	190	88	5	GO:0004252
GeneOntologyMolecularFunction	signaling receptor regulator activity	CER1 CARTPT IL13 ADIPOQ WNT3 AGRP CHGB CTSG GDF11	1.56e-03	616	88	9	GO:0030545
GeneOntologyMolecularFunction	inorganic molecular entity transmembrane transporter activity	SLC6A6 SLC9A5 SLC39A2 SLC9B2 CACNA1I SLC46A1 KCNK7 SLC39A5 SLC4A9 TMEM63A	1.83e-03	758	88	10	GO:0015318
GeneOntologyMolecularFunction	organic anion transmembrane transporter activity	SLC6A6 SLCO2B1 SLC46A1 SLC39A5 SLC4A9 SLC52A3	1.88e-03	293	88	6	GO:0008514
GeneOntologyMolecularFunction	solute:monoatomic cation symporter activity	SLC6A6 SLC46A1 SLC39A5 SLC4A9	1.90e-03	119	88	4	GO:0015294
GeneOntologyMolecularFunction	active monoatomic ion transmembrane transporter activity	SLC6A6 SLC9A5 SLC9B2 SLC46A1 SLC39A5 SLC4A9	2.15e-03	301	88	6	GO:0022853
GeneOntologyMolecularFunction	sodium:proton antiporter activity	SLC9A5 SLC9B2	2.21e-03	16	88	2	GO:0015385
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	VLDLR LRP10	2.21e-03	16	88	2	GO:0005041
GeneOntologyMolecularFunction	serine-type peptidase activity	RHBDL2 CTSC TPSG1 OVCH1 CTSG	2.23e-03	207	88	5	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	RHBDL2 CTSC TPSG1 OVCH1 CTSG	2.47e-03	212	88	5	GO:0017171
GeneOntologyMolecularFunction	acetylcholine-gated monoatomic cation-selective channel activity	CHRNE CHRNG	2.50e-03	17	88	2	GO:0022848
GeneOntologyMolecularFunction	endopeptidase activity	RHBDL2 GPAA1 CTSC TPSG1 BACE2 OVCH1 CTSG	2.90e-03	430	88	7	GO:0004175
GeneOntologyMolecularFunction	hormone activity	CARTPT ADIPOQ AGRP CHGB	3.01e-03	135	88	4	GO:0005179
GeneOntologyMolecularFunction	insulin-like growth factor binding	IGFALS IGFBP4	3.13e-03	19	88	2	GO:0005520
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	VLDLR LRP10	3.82e-03	21	88	2	GO:0030228
GeneOntologyMolecularFunction	symporter activity	SLC6A6 SLC46A1 SLC39A5 SLC4A9	4.38e-03	150	88	4	GO:0015293
GeneOntologyMolecularFunction	acetylcholine receptor activity	CHRNE CHRNG	4.57e-03	23	88	2	GO:0015464
GeneOntologyMolecularFunction	zinc ion transmembrane transporter activity	SLC39A2 SLC39A5	4.98e-03	24	88	2	GO:0005385
GeneOntologyMolecularFunction	cytokine activity	CER1 IL13 ADIPOQ WNT3 GDF11	4.98e-03	250	88	5	GO:0005125
GeneOntologyMolecularFunction	growth factor binding	IGFALS IGFBP4 LRRC32 FGFR4	5.03e-03	156	88	4	GO:0019838
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC6A6 SLC9A5 SLCO2B1 SLC9B2 SLC46A1 SLC39A5 SLC4A9	5.11e-03	477	88	7	GO:0022804
GeneOntologyMolecularFunction	opsonin binding	CALR VSIG4	5.39e-03	25	88	2	GO:0001846
GeneOntologyMolecularFunction	metal cation:proton antiporter activity	SLC9A5 SLC9B2	6.27e-03	27	88	2	GO:0051139
GeneOntologyMolecularFunction	cargo receptor activity	VLDLR LRP10 SURF4	6.30e-03	85	88	3	GO:0038024
GeneOntologyBiologicalProcess	monoatomic ion transmembrane transport	SLC6A6 IL13 PLLP CD4 SLC9A5 SLC39A2 SLC9B2 CACNA1I SLC46A1 TLR9 KCNK7 SLC39A5 SLC4A9 CHRNE CHRNG TMEM63A	2.02e-05	1115	89	16	GO:0034220
GeneOntologyBiologicalProcess	monoatomic cation transmembrane transport	SLC6A6 IL13 CD4 SLC9A5 SLC39A2 SLC9B2 CACNA1I SLC46A1 TLR9 KCNK7 SLC39A5 SLC4A9 CHRNE TMEM63A	4.88e-05	942	89	14	GO:0098655
GeneOntologyBiologicalProcess	monoatomic ion transport	SLC6A6 IL13 PLLP CD4 SLC9A5 SLC39A2 SLCO2B1 SLC9B2 CACNA1I SLC46A1 TLR9 KCNK7 SLC39A5 SLC4A9 CHRNE CHRNG TMEM63A	7.03e-05	1374	89	17	GO:0006811
GeneOntologyCellularComponent	basolateral plasma membrane	SLC6A6 SLCO2B1 SLC9B2 SLC46A1 TLR9 SLC39A5 SLC4A9 CDH16	6.66e-05	320	89	8	GO:0016323
GeneOntologyCellularComponent	endoplasmic reticulum lumen	CD4 ARSA IGFBP4 CALR WNT3 CTSC TOR1A CHGB	8.60e-05	332	89	8	GO:0005788
GeneOntologyCellularComponent	secretory granule	CARTPT ADGRG3 ARSA TMEM190 DSG1 CALR CTSC SURF4 TOR1A CHGB BACE2 CTSG TREML1 TMEM63A	9.31e-05	1014	89	14	GO:0030141
GeneOntologyCellularComponent	basal plasma membrane	SLC6A6 SLCO2B1 SLC9B2 SLC46A1 TLR9 SLC39A5 SLC4A9 CDH16	1.34e-04	354	89	8	GO:0009925
GeneOntologyCellularComponent	basal part of cell	SLC6A6 SLCO2B1 SLC9B2 SLC46A1 TLR9 SLC39A5 SLC4A9 CDH16	2.09e-04	378	89	8	GO:0045178
GeneOntologyCellularComponent	apical part of cell	SLC6A6 VLDLR DSG1 SLCO2B1 SLC9B2 SLC46A1 C1QTNF5 TLR9 SLC4A9 SLC52A3	2.10e-04	592	89	10	GO:0045177
GeneOntologyCellularComponent	secretory vesicle	CARTPT ADGRG3 ARSA TMEM190 DSG1 CALR CTSC SURF4 SLC9B2 TOR1A CHGB BACE2 CTSG TREML1 TMEM63A	2.32e-04	1246	89	15	GO:0099503
GeneOntologyCellularComponent	lysosome	VLDLR ARSA CALR CTSC SURF4 SLC9B2 GNLY TLR9 CTSG PLA2G15 TMEM63A	6.49e-04	811	89	11	GO:0005764
GeneOntologyCellularComponent	lytic vacuole	VLDLR ARSA CALR CTSC SURF4 SLC9B2 GNLY TLR9 CTSG PLA2G15 TMEM63A	6.49e-04	811	89	11	GO:0000323
GeneOntologyCellularComponent	apical plasma membrane	SLC6A6 DSG1 SLCO2B1 SLC9B2 SLC46A1 C1QTNF5 TLR9 SLC52A3	1.11e-03	487	89	8	GO:0016324
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	ADGRG3 CD4 SLC9A5 TMEM190 DSG1 CALR WNT3 SURF4 SLC9B2 TOR1A SLC46A1 TLR9 BACE2 TMEM63A	1.21e-03	1307	89	14	GO:0030659
GeneOntologyCellularComponent	Golgi lumen	WNT3 AGRP MUC5B HS3ST1	1.22e-03	109	89	4	GO:0005796
GeneOntologyCellularComponent	vesicle membrane	ADGRG3 CD4 SLC9A5 TMEM190 DSG1 CALR WNT3 SURF4 SLC9B2 TOR1A SLC46A1 TLR9 BACE2 TMEM63A	1.37e-03	1325	89	14	GO:0012506
GeneOntologyCellularComponent	cytolytic granule	CALR GNLY	1.58e-03	14	89	2	GO:0044194
GeneOntologyCellularComponent	vacuole	VLDLR ARSA CALR CTSC SURF4 SLC9B2 GNLY TLR9 CTSG PLA2G15 TMEM63A	1.69e-03	913	89	11	GO:0005773
GeneOntologyCellularComponent	extracellular matrix	ADIPOQ IGFALS CALR WNT3 CTSC LRRC32 LAMC3 MUC5B CTSG	1.90e-03	656	89	9	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADIPOQ IGFALS CALR WNT3 CTSC LRRC32 LAMC3 MUC5B CTSG	1.94e-03	658	89	9	GO:0030312
GeneOntologyCellularComponent	acetylcholine-gated channel complex	CHRNE CHRNG	2.62e-03	18	89	2	GO:0005892
GeneOntologyCellularComponent	endoplasmic reticulum-Golgi intermediate compartment	LMAN2L CALR CTSC SURF4	3.11e-03	141	89	4	GO:0005793
GeneOntologyCellularComponent	azurophil granule	ARSA CTSC SURF4 CTSG	4.87e-03	160	89	4	GO:0042582
GeneOntologyCellularComponent	primary lysosome	ARSA CTSC SURF4 CTSG	4.87e-03	160	89	4	GO:0005766
GeneOntologyCellularComponent	endoplasmic reticulum-Golgi intermediate compartment membrane	CALR CTSC SURF4	5.01e-03	81	89	3	GO:0033116
GeneOntologyCellularComponent	endocytic vesicle lumen	CALR GNLY	5.05e-03	25	89	2	GO:0071682
Domain	Ldl_recept_a	VLDLR LRP10 C1QTNF5 MAMDC4	5.41e-05	45	86	4	PF00057
Domain	LDLRA_1	VLDLR LRP10 C1QTNF5 MAMDC4	6.99e-05	48	86	4	PS01209
Domain	LDLRA_2	VLDLR LRP10 C1QTNF5 MAMDC4	7.58e-05	49	86	4	PS50068
Domain	LDrepeatLR_classA_rpt	VLDLR LRP10 C1QTNF5 MAMDC4	7.58e-05	49	86	4	IPR002172
Domain	LDLa	VLDLR LRP10 C1QTNF5 MAMDC4	7.58e-05	49	86	4	SM00192
Domain	C1Q	C1QL2 ADIPOQ C1QTNF5	4.25e-04	32	86	3	SM00110
Domain	C1q	C1QL2 ADIPOQ C1QTNF5	4.25e-04	32	86	3	PF00386
Domain	C1q_dom	C1QL2 ADIPOQ C1QTNF5	5.09e-04	34	86	3	IPR001073
Domain	C1Q	C1QL2 ADIPOQ C1QTNF5	5.09e-04	34	86	3	PS50871
Domain	LDLR_class-A_CS	VLDLR LRP10 MAMDC4	8.23e-04	40	86	3	IPR023415
Domain	-	VLDLR LRP10 MAMDC4	1.24e-03	46	86	3	4.10.400.10
Domain	CUB	LRP10 C1QTNF5 OVCH1	1.49e-03	49	86	3	PF00431
Domain	-	C1QL2 ADIPOQ C1QTNF5	1.58e-03	50	86	3	2.60.120.40
Domain	CUB	LRP10 C1QTNF5 OVCH1	1.58e-03	50	86	3	SM00042
Domain	Na_H_Exchanger	SLC9A5 SLC9B2	1.84e-03	14	86	2	PF00999
Domain	Zip	SLC39A2 SLC39A5	1.84e-03	14	86	2	PF02535
Domain	Cation/H_exchanger	SLC9A5 SLC9B2	1.84e-03	14	86	2	IPR006153
Domain	ZIP	SLC39A2 SLC39A5	1.84e-03	14	86	2	IPR003689
Domain	CUB	LRP10 C1QTNF5 OVCH1	1.87e-03	53	86	3	PS01180
Domain	CUB_dom	LRP10 C1QTNF5 OVCH1	2.31e-03	57	86	3	IPR000859
Domain	Nicotinic_acetylcholine_rcpt	CHRNE CHRNG	2.41e-03	16	86	2	IPR002394
Domain	Tumour_necrosis_fac-like_dom	C1QL2 ADIPOQ C1QTNF5	2.42e-03	58	86	3	IPR008983
Domain	CTCK_1	CER1 MUC5B	3.06e-03	18	86	2	PS01185
Domain	CT	CER1 MUC5B	4.56e-03	22	86	2	SM00041
Domain	-	CHRNE CHRNG	4.98e-03	23	86	2	1.20.120.370
Domain	Acetylcholine_rcpt_TM	CHRNE CHRNG	4.98e-03	23	86	2	IPR027361
Domain	Frizzled_dom	FRZB C1QTNF5	5.42e-03	24	86	2	IPR020067
Domain	FZ	FRZB C1QTNF5	5.42e-03	24	86	2	PS50038
Domain	Fz	FRZB C1QTNF5	5.42e-03	24	86	2	PF01392
Domain	Cys_knot_C	CER1 MUC5B	5.87e-03	25	86	2	IPR006207
Domain	CTCK_2	CER1 MUC5B	5.87e-03	25	86	2	PS01225
Domain	Collagen	C1QL2 ADIPOQ C1QTNF5	7.10e-03	85	86	3	IPR008160
Domain	Collagen	C1QL2 ADIPOQ C1QTNF5	7.10e-03	85	86	3	PF01391
Pubmed	Signal peptide prediction based on analysis of experimentally verified cleavage sites.	CER1 CARTPT ADGRG3 CD4 ADIPOQ FRZB VSIG4 C1QTNF5 FGFR4 PLA2G15	1.61e-09	264	89	10	15340161
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	SLC6A6 THEM6 ARSA LMAN2L GPAA1 IGFBP4 LRP10 RPN1 CALR CTSC SURF4 TOR1A LAMC3 FGFR4 BACE2 PLA2G15 GPR107	9.17e-09	1201	89	17	35696571
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	FICD LMAN2L LRP10 FAM24B ZG16B VSIG4 C1QTNF5 TLR9 BACE2 MFSD13A TREML1 MAMDC4 PLA2G15 CDH16	2.07e-07	985	89	14	12975309
Pubmed	Molecular, biochemical and functional characterizations of C1q/TNF family members: adipose-tissue-selective expression patterns, regulation by PPAR-gamma agonist, cysteine-mediated oligomerizations, combinatorial associations and metabolic functions.	C1QL2 ADIPOQ C1QTNF5	3.50e-06	12	89	3	18783346
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	DSG1 LRP10 RPN1 CTSC MUC5B PLA2G15	4.22e-06	164	89	6	32409323
Pubmed	The crystal structure of a complement-1q family protein suggests an evolutionary link to tumor necrosis factor.	ADIPOQ C1QTNF5	6.48e-06	2	89	2	9512423
Pubmed	Adiponectin exerts cardioprotection against ischemia/reperfusion injury partially via calreticulin mediated anti-apoptotic and anti-oxidative actions.	ADIPOQ CALR	6.48e-06	2	89	2	27757734
Pubmed	Adiponectin Mediates Dietary Omega-3 Long-Chain Polyunsaturated Fatty Acid Protection Against Choroidal Neovascularization in Mice.	VLDLR ADIPOQ	6.48e-06	2	89	2	28763559
Pubmed	Escobar syndrome is a prenatal myasthenia caused by disruption of the acetylcholine receptor fetal gamma subunit.	CHRNE CHRNG	6.48e-06	2	89	2	16826520
Pubmed	Primary structure of the human muscle acetylcholine receptor. cDNA cloning of the gamma and epsilon subunits.	CHRNE CHRNG	6.48e-06	2	89	2	7688301
Pubmed	Asymmetric transmitter binding sites of fetal muscle acetylcholine receptors shape their synaptic response.	CHRNE CHRNG	6.48e-06	2	89	2	23898191
Pubmed	Functional ablation of the mouse Ldb1 gene results in severe patterning defects during gastrulation.	CER1 WNT3 FRZB	1.52e-05	19	89	3	12490556
Pubmed	Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.	SLC6A6 LMAN2L GPAA1 IGFBP4 LRP10 SURF4 ALG5 UPK3B TOR1A SLC46A1 HIBADH CDH16	1.67e-05	1061	89	12	33845483
Pubmed	The Role of IL-13, IL-15 and Granulysin in the Pathogenesis of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis.	IL13 GNLY	1.94e-05	3	89	2	33560872
Pubmed	A universal oligonucleotide probe for acetylcholine receptor genes. Selection and sequencing of cDNA clones for the mouse muscle beta subunit.	CHRNE CHRNG	1.94e-05	3	89	2	3782129
Pubmed	Investigation of melanocortin system gene variants in antipsychotic-induced weight gain.	CARTPT AGRP	1.94e-05	3	89	2	24564533
Pubmed	Dipeptidyl peptidase I-dependent neutrophil recruitment modulates the inflammatory response to Sendai virus infection.	CTSC CTSG	1.94e-05	3	89	2	18292580
Pubmed	The acetylcholine receptor gamma-to-epsilon switch occurs in individual endplates.	CHRNE CHRNG	1.94e-05	3	89	2	15883046
Pubmed	SCART scavenger receptors identify a novel subset of adult gammadelta T cells.	CD4 SCART1	1.94e-05	3	89	2	18641307
Pubmed	Changes in mRNA expression of nicotinic acetylcholine receptor subunits during embryonic development of mouse masseter muscle.	CHRNE CHRNG	1.94e-05	3	89	2	12012784
Pubmed	Differential effects of dendritic cell transfer on airway hyperresponsiveness and inflammation.	IL13 CD4	1.94e-05	3	89	2	19151321
Pubmed	Adiponectin modulates inflammatory reactions via calreticulin receptor-dependent clearance of early apoptotic bodies.	ADIPOQ CALR	1.94e-05	3	89	2	17256056
Pubmed	S-540956, a CpG Oligonucleotide Annealed to a Complementary Strand With an Amphiphilic Chain Unit, Acts as a Potent Cancer Vaccine Adjuvant by Targeting Draining Lymph Nodes.	CD4 TLR9	1.94e-05	3	89	2	35003132
Pubmed	Adiponectin inhibits Toll-like receptor family-induced signaling.	ADIPOQ TLR9	3.87e-05	4	89	2	16325814
Pubmed	Characterization of hematopoietic progenitor mobilization in protease-deficient mice.	CTSC CTSG	3.87e-05	4	89	2	15010367
Pubmed	Mutations that stabilize the open state of the Erwinia chrisanthemi ligand-gated ion channel fail to change the conformation of the pore domain in crystals.	CHRNE CHRNG	3.87e-05	4	89	2	22474383
Pubmed	Ancestral Circuits for the Coordinated Modulation of Brain State.	CARTPT AGRP	3.87e-05	4	89	2	29103613
Pubmed	Toll-like receptor ligands directly promote activated CD4+ T cell survival.	CD4 TLR9	3.87e-05	4	89	2	15128790
Pubmed	Developmental changes in the nicotinic acetylcholine receptor in mouse tongue striated muscle.	CHRNE CHRNG	3.87e-05	4	89	2	11926244
Pubmed	ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.	IL13 MUC5B	3.87e-05	4	89	2	31582416
Pubmed	Neutrophil serine proteases promote IL-1β generation and injury in necrotizing crescentic glomerulonephritis.	CTSC CTSG	3.87e-05	4	89	2	22241891
Pubmed	TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.	IL13 MUC5B	3.87e-05	4	89	2	23249391
Pubmed	Neutrophils and neutrophil serine proteases are increased in the spleens of estrogen-treated C57BL/6 mice and several strains of spontaneous lupus-prone mice.	CTSC CTSG	3.87e-05	4	89	2	28192517
Pubmed	Serum adiponectin, TNF-α, IL-12p70, and IL-13 levels in multiple sclerosis and the effects of different therapy regimens.	IL13 ADIPOQ	3.87e-05	4	89	2	20714168
Pubmed	Analysis of 30 genes (355 SNPS) related to energy homeostasis for association with adiposity in European-American and Yup'ik Eskimo populations.	CARTPT ADIPOQ AGRP	6.26e-05	30	89	3	19077438
Pubmed	Conditional knockdown of Fgfr2 in mice using Cre-LoxP induced RNA interference.	HHAT FGFR4	6.44e-05	5	89	2	15987787
Pubmed	Pim2 cooperates with PML-RARalpha to induce acute myeloid leukemia in a bone marrow transplantation model.	ADIPOQ CTSG	6.44e-05	5	89	2	20215640
Pubmed	Transsynaptic Modulation of Kainate Receptor Functions by C1q-like Proteins.	C1QL2 NRXN3	6.44e-05	5	89	2	27133466
Pubmed	Properties of embryonic and adult muscle acetylcholine receptors transiently expressed in COS cells.	CHRNE CHRNG	6.44e-05	5	89	2	2383398
Pubmed	Relative tissue expression of homologous torsinB correlates with the neuronal specific importance of DYT1 dystonia-associated torsinA.	CALR TOR1A	6.44e-05	5	89	2	20015956
Pubmed	A large-scale candidate gene association study of age at menarche and age at natural menopause.	ADIPOQ IGFALS IGFBP4 GDF11 CHRNE CHRNG	7.76e-05	275	89	6	20734064
Pubmed	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	ADIPOQ SURF4 FGFR4	8.36e-05	33	89	3	22703881
Pubmed	Inflammation-related neutrophil proteases, cathepsin G and elastase, function as insulin-like growth factor binding protein proteases.	IGFALS CTSG	9.65e-05	6	89	2	10512690
Pubmed	Evolution of nicotinic acetylcholine receptor subunits.	CHRNE CHRNG	9.65e-05	6	89	2	9580980
Pubmed	Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense.	CTSC CTSG	9.65e-05	6	89	2	22163282
Pubmed	Getting your head around Hex and Hesx1: forebrain formation in mouse.	CER1 WNT3	9.65e-05	6	89	2	11291863
Pubmed	Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries.	THEM6 LMAN2L VSIG4 TOR1A LAMC3 PLA2G15 SLC52A3	1.21e-04	430	89	7	16303743
Pubmed	Sterile Inflammation Enhances ECM Degradation in Integrin β1 KO Embryonic Skin.	IL13 CD4 LAMC3	1.28e-04	38	89	3	27653694
Pubmed	Melanocortin-4 receptor gene and physical activity in the Québec Family Study.	CARTPT AGRP	1.35e-04	7	89	2	15597110
Pubmed	A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.	IL13 LRRC32	1.35e-04	7	89	2	23886662
Pubmed	Neuromuscular junction immaturity and muscle atrophy are hallmarks of the ColQ-deficient mouse, a model of congenital myasthenic syndrome with acetylcholinesterase deficiency.	CHRNE CHRNG	1.79e-04	8	89	2	26993635
Pubmed	Rac1-dependent collective cell migration is required for specification of the anterior-posterior body axis of the mouse.	CER1 WNT3	1.79e-04	8	89	2	20689803
Pubmed	Essential roles of the acetylcholine receptor gamma-subunit in neuromuscular synaptic patterning.	CHRNE CHRNG	1.79e-04	8	89	2	18434415
Pubmed	Aberrant development of motor axons and neuromuscular synapses in MyoD-null mice.	CHRNE CHRNG	1.79e-04	8	89	2	12832540
Pubmed	A signaling principle for the specification of the germ cell lineage in mice.	CER1 WNT3	2.30e-04	9	89	2	19410550
Pubmed	A family of Acrp30/adiponectin structural and functional paralogs.	ADIPOQ C1QTNF5	2.30e-04	9	89	2	15231994
Pubmed	Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos.	CER1 WNT3	2.88e-04	10	89	2	21554866
Pubmed	Microbiota-modulated CART+ enteric neurons autonomously regulate blood glucose.	CARTPT AGRP	2.88e-04	10	89	2	32855216
Pubmed	Concordance of two multiple analytical approaches demonstrate that interaction between BMI and ADIPOQ haplotypes is a determinant of LDL cholesterol in a general French population.	CARTPT ADIPOQ	2.88e-04	10	89	2	20186155
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	THEM6 MAGEB2 LMAN2L RPN1 CALR ALG5 UPK3B	3.15e-04	503	89	7	36217030
Pubmed	Expression of Wnt signalling pathway genes during tooth development.	WNT3 FRZB	3.51e-04	11	89	2	10415363
Pubmed	NLRP3 inflammasome plays a redundant role with caspase 8 to promote IL-1β-mediated osteomyelitis.	CTSC CTSG	3.51e-04	11	89	2	27071119
Pubmed	Evolutionarily conserved regulators of tau identify targets for new therapies.	THEM6 DSG1 RPN1 CALR SURF4 ALG5 FGFR4	3.67e-04	516	89	7	36610398
Pubmed	Cell Surface Proteomic Map of HIV Infection Reveals Antagonism of Amino Acid Metabolism by Vpu and Nef.	SLC6A6 VLDLR CD4 NRXN3	3.77e-04	132	89	4	26439863
Pubmed	Pten regulates collective cell migration during specification of the anterior-posterior axis of the mouse embryo.	CER1 WNT3	4.20e-04	12	89	2	22342906
Pubmed	HIV-1 Nef plays an essential role in two independent processes in CD4 down-regulation: dissociation of the CD4-p56(lck) complex and targeting of CD4 to lysosomes.	CD4 PIK3C2B	4.20e-04	12	89	2	10208934
Pubmed	Temperature dependence of the control of energy homeostasis requires CART signaling.	CARTPT AGRP	4.20e-04	12	89	2	27080622
Pubmed	Comparative Transcriptomic Analyses of Developing Melanocortin Neurons Reveal New Regulators for the Anorexigenic Neuron Identity.	CARTPT AGRP	4.20e-04	12	89	2	32213554
Pubmed	TLR9-independent CD8+ T cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling.	CD4 TLR9	4.20e-04	12	89	2	38053332
Pubmed	Epithelial Wnt/β-catenin signaling regulates palatal shelf fusion through regulation of Tgfβ3 expression.	WNT3 FRZB	4.20e-04	12	89	2	21185284
Pubmed	Defects of the body plan of mutant embryos lacking Lim1, Otx2 or Hnf3beta activity.	CER1 WNT3	4.20e-04	12	89	2	11291865
Pubmed	Wnt3 signaling in the epiblast is required for proper orientation of the anteroposterior axis.	CER1 WNT3	4.20e-04	12	89	2	18028899
Pubmed	Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin.	CARTPT CHGB	4.20e-04	12	89	2	33833454
Pubmed	Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.	ARSA IGFBP4 FRZB C1QTNF5 PLA2G15	4.51e-04	248	89	5	24006456
Pubmed	High-density association study of 383 candidate genes for volumetric BMD at the femoral neck and lumbar spine among older men.	CER1 ADIPOQ IGFALS IGFBP4 CYP21A2 FRZB	4.62e-04	383	89	6	19453261
Pubmed	Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling.	FRZB UNC5C LAMC3	4.75e-04	59	89	3	31351040
Pubmed	CD25+CD4+ cells contribute to Th2 polarization during helminth infection by suppressing Th1 response development.	IL13 CD4	4.96e-04	13	89	2	15240714
Pubmed	Borcs6 is required for endo-lysosomal degradation during early development.	CER1 WNT3	4.96e-04	13	89	2	35726782
Pubmed	HIV-1 Nef in macrophage-mediated disease pathogenesis.	CD4 PIK3C2B	4.96e-04	13	89	2	23215766
Pubmed	Lymphotoxin-β receptor signaling through NF-κB2-RelB pathway reprograms adipocyte precursors as lymph node stromal cells.	CD4 ADIPOQ	4.96e-04	13	89	2	22940098
Pubmed	Reciprocal regulation of Wnt and Gpr177/mouse Wntless is required for embryonic axis formation.	CER1 WNT3	4.96e-04	13	89	2	19841259
Pubmed	Evolution of odorant receptors expressed in mammalian testes.	OR8D1 OR1E2	4.96e-04	13	89	2	11014824
Pubmed	A multi-centre study of candidate genes for wheeze and allergy: the International Study of Asthma and Allergies in Childhood Phase 2.	IL13 TLR9	5.78e-04	14	89	2	20085599
Pubmed	Design and expression of human alpha7 nicotinic acetylcholine receptor extracellular domain mutants with enhanced solubility and ligand-binding properties.	CHRNE CHRNG	5.78e-04	14	89	2	19059502
Pubmed	Nuclear receptor NR5A2 is required for proper primitive streak morphogenesis.	CER1 WNT3	5.78e-04	14	89	2	17075876
Pubmed	FGF8 is essential for formation of the ductal system in the male reproductive tract.	HHAT FGFR4	6.65e-04	15	89	2	22110055
Pubmed	Analysis of nicotinic acetylcholine receptor subunits in the cochlea of the mouse.	CHRNE CHRNG	6.65e-04	15	89	2	8838678
Pubmed	LC-MS/MS Based Quantitation of ABC and SLC Transporter Proteins in Plasma Membranes of Cultured Primary Human Retinal Pigment Epithelium Cells and Immortalized ARPE19 Cell Line.	SLC6A6 SLC46A1	6.65e-04	15	89	2	28112518
Pubmed	Disrupting hedgehog and WNT signaling interactions promotes cleft lip pathogenesis.	HHAT FRZB	6.65e-04	15	89	2	24590292
Pubmed	A phenotype-sensitizing Apoe-deficient genetic background reveals novel atherosclerosis predisposition loci in the mouse.	VLDLR CTSG	6.65e-04	15	89	2	11973313
Pubmed	Quantitative trait loci for steady-state platelet count in mice.	OR1E2 SLC46A1	6.65e-04	15	89	2	15520881
Pubmed	Requirement for Wnt3 in vertebrate axis formation.	CER1 WNT3	6.65e-04	15	89	2	10431240
Pubmed	Strain-specific modifier genes of Cecr2-associated exencephaly in mice: genetic analysis and identification of differentially expressed candidate genes.	VLDLR MFSD13A	6.65e-04	15	89	2	22045912
Pubmed	Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo.	CER1 WNT3	6.65e-04	15	89	2	11171400
Pubmed	Bmpr1a is required for proper migration of the AVE through regulation of Dkk1 expression in the pre-streak mouse embryo.	CER1 WNT3	7.59e-04	16	89	2	20211162
Pubmed	Multiple distinct risk loci for nicotine dependence identified by dense coverage of the complete family of nicotinic receptor subunit (CHRN) genes.	CHRNE CHRNG	7.59e-04	16	89	2	19259974
Pubmed	Human colostrum: identification of minor proteins in the aqueous phase by proteomics.	CALR CTSC ZG16B MUC5B	8.14e-04	162	89	4	16502470
Pubmed	Mesd encodes an LRP5/6 chaperone essential for specification of mouse embryonic polarity.	CER1 WNT3	8.59e-04	17	89	2	12581525
Pubmed	Axis specification and morphogenesis in the mouse embryo require Nap1, a regulator of WAVE-mediated actin branching.	CER1 WNT3	8.59e-04	17	89	2	16831833
Pubmed	GATA-3 regulates the development and function of invariant NKT cells.	IL13 CD4	8.59e-04	17	89	2	17082577
Interaction	TMEM106B interactions	THEM6 LMAN2L GPAA1 RPN1 CALR CTSC SURF4 TOR1A LAMC3	5.07e-06	309	83	9	int:TMEM106B
Cytoband	Ensembl 112 genes in cytogenetic band chr9q34	SURF4 TOR1A LAMC3 MAMDC4 GPR107	4.40e-04	325	89	5	chr9q34
Cytoband	Ensembl 112 genes in cytogenetic band chr16q22	SLC9A5 AGRP PLA2G15 CDH16	4.58e-04	183	89	4	chr16q22
Cytoband	16q22.1	SLC9A5 PLA2G15 CDH16	1.31e-03	110	89	3	16q22.1
GeneFamily	Solute carriers	SLC6A6 SLC9A5 SLC39A2 SLCO2B1 SLC9B2 SLC46A1 SLC39A5 SLC4A9 SLC52A3	4.95e-06	395	59	9	752
GeneFamily	Endogenous ligands\|C1q and TNF related	C1QL2 ADIPOQ C1QTNF5	2.60e-05	18	59	3	1372
GeneFamily	Low density lipoprotein receptors	VLDLR LRP10	7.98e-04	13	59	2	634
GeneFamily	Cathepsins	CTSC CTSG	1.07e-03	15	59	2	470
GeneFamily	Cholinergic receptors nicotinic subunits	CHRNE CHRNG	1.22e-03	16	59	2	173
GeneFamily	Endogenous ligands	ADIPOQ WNT3 AGRP CTSG	7.46e-03	237	59	4	542
CoexpressionAtlas	gudmap_RNAseq_e15.5_Endothelial_2500_K1	ADGRG3 RHBDL2 ARSA IGFBP4 ST8SIA6 TMEM190 LRP10 PIK3C2B RPN1 ALG5 UNC5C CCDC3 BACE2 HS3ST1 MFSD13A TMEM63A SLC52A3	2.72e-05	1377	85	17	gudmap_RNAseq_e15.5_Endothelial_2500_K1
CoexpressionAtlas	DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#4_top-relative-expression-ranked_500	VLDLR ST8SIA6 FGFR4 SLC39A5 SLC52A3	3.99e-05	95	85	5	gudmap_developingKidney_e15.5_Proximal Tubules_500_k4
ToppCell	droplet-Marrow-nan-18m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 IGFBP4 RPN1 CALR SURF4 MFSD13A CTSG	1.10e-07	190	89	7	240923769fef18eaf73d2efa3d5f745f5533b0ce
ToppCell	356C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	IGFBP4 CALR SLCO2B1 CTSC VSIG4 SLC46A1 HS3ST1	1.10e-07	190	89	7	d541e076137cf7334bdb0ed69db2f9a27c668c65
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 IGFBP4 RPN1 CALR SURF4 MFSD13A CTSG	1.10e-07	190	89	7	9df9b9e91c97e504c189d6055a6aabc54ad17cec
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IGFBP4 ST8SIA6 FRZB LRRC32 CCDC3 LAMC3 TMEM35B	1.36e-07	196	89	7	12d9028f90c057c6e5cff00301793fa550e86c5a
ToppCell	facs-Trachea-3m-Hematologic-myeloid-granulocyte-granulocyte_l26\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL13 TPSG1 HS3ST1 CTSG SLC39A5 SLC52A3	1.00e-06	165	89	6	23955e3373660f827518e723ac62fba99753f375
ToppCell	moderate-Myeloid-Mast_cell\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	ST8SIA6 PIK3C2B WNT3 BACE2 CTSG GDF11	1.04e-06	166	89	6	c3835b424c63bf11a4e2c47635dc3787fc4a637a
ToppCell	droplet-Lung-nan-18m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL13 ADGRG3 AGRP MUC5B CTSG TREML1	1.15e-06	169	89	6	f2e20049a17eee533d49bd5f24a51962d123d132
ToppCell	droplet-Lung-nan-18m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL13 ADGRG3 AGRP MUC5B CTSG TREML1	1.15e-06	169	89	6	4c6892551e9dec94fc62b3beab1e6d424639a1e9
ToppCell	NS-critical-d_0-4-Epithelial-Secretory\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	VLDLR RHBDL2 NRXN3 ZG16B MUC5B BACE2	1.15e-06	169	89	6	aec97583b23112060437b619cb429dc32f29285f
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac\|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass	SLCO2B1 CTSC AGRP VSIG4 OVCH1 PLA2G15	1.32e-06	173	89	6	4efa0878ed1ede8fa5d6c191a76d4f70558ba761
ToppCell	10x3'2.3-week_17-19-Hematopoietic-HSC/MPP_and_pro-eo/baso/mast_precursor\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	IL13 MAGEB2 ST8SIA6 CACNA1I TPSG1 BACE2	1.37e-06	174	89	6	64d13a7a9757e85f4f4af876c687dd18a7efa01a
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN3 PIK3C2B BACE2 HS3ST1 MFSD13A SLC52A3	1.56e-06	178	89	6	5cc182e6faa7ba5b88378d2c953be29bbbb95a7e
ToppCell	10x5'-GI_large-bowel-Mast\|GI_large-bowel / Manually curated celltypes from each tissue	ST8SIA6 SLCO2B1 TPSG1 BACE2 HS3ST1 CTSG	1.56e-06	178	89	6	d10ed2543c96e1a2373f847e0b82144771e26d07
ToppCell	3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD4 SLCO2B1 CTSC VSIG4 OVCH1 PLA2G15	1.56e-06	178	89	6	0b398656f26c4061b11ccf98908d0e2e1367585a
ToppCell	facs-Lung-Endomucin-3m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NRXN3 PIK3C2B BACE2 HS3ST1 MFSD13A SLC52A3	1.56e-06	178	89	6	f9a16bc3f09c35c7d30e3809da024bc2dcf746ed
ToppCell	10x5'-GI_large-bowel-Mast-Mast_cells\|GI_large-bowel / Manually curated celltypes from each tissue	ST8SIA6 SLCO2B1 TPSG1 BACE2 HS3ST1 CTSG	1.56e-06	178	89	6	8fc5f735afa25ae43c2acb1c710ade6e9e093e3c
ToppCell	3'_v3-lymph-node_spleen-Mast-Mast_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	IL13 MAGEB2 TPSG1 BACE2 HS3ST1 CTSG	1.89e-06	184	89	6	ed266bd2d12f86e8786473e64fbcd58319cd4c2a
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RHBDL2 FRZB LRRC32 CCDC3 LAMC3 C1QTNF5	2.01e-06	186	89	6	6568358812f0ca4e0161a1a1b29682fbced35c79
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_CCL3+-Alveolar_macrophage_CCL3+_L.1.0.2.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CD4 SLCO2B1 CTSC AGRP VSIG4 PLA2G15	2.21e-06	189	89	6	a59025e82fabd9d60e2438dee85b2644478cc7c8
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.4\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CALR SLCO2B1 CTSC VSIG4 GNLY PLA2G15	2.21e-06	189	89	6	6cdd743bc46e34dc48288dda343309131b6c2d5f
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_2\|343B / Donor, Lineage, Cell class and subclass (all cells)	CD4 SLCO2B1 AGRP VSIG4 OVCH1 PLA2G15	2.28e-06	190	89	6	6514f00d222eef08c282face7f177259bca62f0e
ToppCell	10x3'2.3-week_17-19-Myeloid_macrophage-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CD4 SLCO2B1 CTSC SLC9B2 VSIG4 SLC46A1	2.49e-06	193	89	6	cc77889acbadf1acb278daa0ed0db0253acf041d
ToppCell	10x3'2.3-week_17-19-Myeloid_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CD4 SLCO2B1 CTSC SLC9B2 VSIG4 SLC46A1	2.49e-06	193	89	6	855b605efa4c9ab7948e8aa231865fa0467c06d9
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CD4 SLCO2B1 CTSC VSIG4 SLC46A1 PLA2G15	2.64e-06	195	89	6	c16479a10f5ca2e89aea1742dbc5cc4dc9f3ea88
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CD4 SLCO2B1 WNT3 CTSC SLC9B2 VSIG4	2.72e-06	196	89	6	e0447ad2efb021b63c7fef000d39b6b21fbe6113
ToppCell	10x3'2.3-week_14-16-Myeloid_macrophage-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CD4 SLCO2B1 WNT3 CTSC SLC9B2 VSIG4	2.72e-06	196	89	6	bd2c2de103e28b65ea537c22f71225cb0deef1e0
ToppCell	10x5'v1-week_14-16-Myeloid_macrophage-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CD4 SLCO2B1 WNT3 CTSC SLC9B2 VSIG4	2.72e-06	196	89	6	3bca88eede3dd7368715ced02e3bacd1e3e82cab
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PLLP FAM24B CHGB SLC4A9 CDH16 SLC52A3	2.72e-06	196	89	6	6ee8dcc5cd643747e20d23b9556c17f7c102b19c
ToppCell	10x3'2.3-week_14-16-Myeloid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CD4 SLCO2B1 WNT3 CTSC SLC9B2 VSIG4	2.72e-06	196	89	6	072a4150ae521c6589b0f7cd60e975fb33715bf4
ToppCell	B_cells-Plasma_cells_and_plasmablasts\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	FICD ARSA RPN1 CALR SURF4 ALG5	2.81e-06	197	89	6	3b1c574b3d119b63967bb1306f0353ecc4c522f3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC9A5 FRZB LRRC32 UNC5C CCDC3 LAMC3	2.81e-06	197	89	6	2872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma-stromal_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CD4 IGFBP4 SLCO2B1 CTSC VSIG4 SLC46A1	2.97e-06	199	89	6	2649afa3ccda78e9d1df26127b66cbfa0c6cd01d
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CD4 SLCO2B1 WNT3 CTSC SLC9B2 VSIG4	2.97e-06	199	89	6	980b10b81ee9dc952e3be25bd294201ce5a4ca8b
ToppCell	10x5'v1-week_17-19-Myeloid_macrophage-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	CD4 SLCO2B1 WNT3 CTSC SLC9B2 VSIG4	2.97e-06	199	89	6	cbd423c31d75f6d2f5ae85d2241641fcbe630b81
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD4 SLCO2B1 CTSC AGRP VSIG4 OVCH1	3.06e-06	200	89	6	efdbd1273b07d9fe957380e347b5b6b45db0a271
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CD4 SLCO2B1 CTSC AGRP VSIG4 OVCH1	3.06e-06	200	89	6	9ca86928fceaa1fefd0f9ffcfa5cc0a210ee5792
ToppCell	TCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-2\|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9	SLC6A6 CACNA1I C1QTNF5 BACE2 SLC52A3	1.08e-05	145	89	5	f9aa7f2401e26f1e8cec1112a71c16e1c2784893
ToppCell	facs-Trachea-24m-Hematologic-myeloid-granulocyte-granulocyte_l26\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL13 ADGRG3 TPSG1 HS3ST1 CTSG	1.54e-05	156	89	5	da5cfa8fa9595613f04ce9511f8b42bad34d995a
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	CD4 CTSC GNLY FGFR4 KCNK7	1.85e-05	162	89	5	f0a92c92c3a6cf9fa11fb279a584e7f328cb7d43
ToppCell	URO-Lymphocyte-T_NK-MAIT\|URO / Disease, Lineage and Cell Type	VLDLR IGFBP4 HHAT SLC9B2 TMEM35B	1.96e-05	164	89	5	cb42a70433b3968caca67f7aa98ea536cd90a0bc
ToppCell	10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD56bright_CD16-\|GI_small-bowel / Manually curated celltypes from each tissue	ADGRG3 IGFBP4 ST8SIA6 GNLY RNF217	1.96e-05	164	89	5	36e64e4f717dd59b352c20ff9742ca1e232342bb
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CTSC ZG16B MUC5B BACE2 HS3ST1	2.14e-05	167	89	5	31633899aae852873a4887e72c621474b0a51a33
ToppCell	Club_cells-IPF_03\|World / lung cells shred on cell class, cell subclass, sample id	RHBDL2 ZG16B MUC5B BACE2 HS3ST1	2.14e-05	167	89	5	dbdaaeb3bd9139cb008d9fe24ec031fc5628f136
ToppCell	10x5'-lymph-node_spleen-Mast-Mast_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	ST8SIA6 TPSG1 BACE2 HS3ST1 CTSG	2.20e-05	168	89	5	650ad3ea52577887885d82457dbc04202ce3eb34
ToppCell	10x5'-lymph-node_spleen-Mast\|lymph-node_spleen / Manually curated celltypes from each tissue	ST8SIA6 TPSG1 BACE2 HS3ST1 CTSG	2.20e-05	168	89	5	e58ffbb57c81967766755c3f6f347b158a39cb0d
ToppCell	droplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL13 ADGRG3 AGRP MUC5B CTSG	2.20e-05	168	89	5	0e99ecd94ab8e5372e30433d7d0aa76b4d54257a
ToppCell	droplet-Lung-18m-Hematologic-myeloid-Basophil/Mast_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL13 ADGRG3 AGRP MUC5B CTSG	2.20e-05	168	89	5	34722e14f28313f2e4644b3c1861ef12958cee9f
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NRXN3 CYP21A2 ZG16B MUC5B BACE2	2.27e-05	169	89	5	db73dae011ff3749b3706e50ab46d03b775dd6bb
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NRXN3 CYP21A2 ZG16B MUC5B BACE2	2.27e-05	169	89	5	97b7047b87ce0052d8580565c9b44fd2aa6f0d5c
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NRXN3 CYP21A2 ZG16B MUC5B BACE2	2.27e-05	169	89	5	1a684471dbda42e1470e5a889648666e14f25982
ToppCell	390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)\|390C / Donor, Lineage, Cell class and subclass (all cells)	CD4 SLCO2B1 VSIG4 HS3ST1 PLA2G15	2.27e-05	169	89	5	2c851b2703c7b8b656026f996f5fc027e4a79b36
ToppCell	Club_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	ZG16B MUC5B BACE2 HS3ST1 SLC52A3	2.27e-05	169	89	5	03b303af8a26c6ff196507fe24f5bd3d75d7b1af
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VLDLR FICD IGFBP4 LAMC3 BACE2	2.27e-05	169	89	5	031465190cd3623a25ef2b868daab8d932c8ff08
ToppCell	Control-Myeloid-Mast\|Control / Disease state, Lineage and Cell class	IL13 ST8SIA6 TPSG1 BACE2 CTSG	2.33e-05	170	89	5	9a14deb7f7cd4a49c217eba4023f7bf1dec6c902
ToppCell	facs-Trachea-18m-Hematologic-myeloid-granulocyte-granulocyte_l26\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL13 ADGRG3 TPSG1 CTSG SLC52A3	2.33e-05	170	89	5	4b1c84b35b7242a297ffdb9c23a6d982acf1bed5
ToppCell	Control-Myeloid-Mast\|World / Disease state, Lineage and Cell class	IL13 ST8SIA6 TPSG1 BACE2 CTSG	2.40e-05	171	89	5	ed8e61d524f4cddc6084b261175df54d2a64a60f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ST8SIA6 SLCO2B1 TPSG1 BACE2 CTSG	2.47e-05	172	89	5	3a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCell	ILEUM-inflamed-(4)_Mast\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	IL13 ST8SIA6 TPSG1 HS3ST1 CTSG	2.47e-05	172	89	5	be82f749f4b1049ae8832facc052082cf5463c11
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_artery-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THEM6 IGFBP4 ST8SIA6 PIK3C2B LRRC32	2.47e-05	172	89	5	de9b11ab109d04937186c09772cec9105a935f95
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ST8SIA6 SLCO2B1 TPSG1 BACE2 CTSG	2.47e-05	172	89	5	cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCell	ILEUM-inflamed-(4)_Mast_cells\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	IL13 ST8SIA6 TPSG1 HS3ST1 CTSG	2.47e-05	172	89	5	7185b28282412f3a464b2a8ad5605475a1a31358
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	PLLP ST8SIA6 PIK3C2B LRRC32 SLC52A3	2.54e-05	173	89	5	ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CTSC ZG16B MUC5B BACE2 HS3ST1	2.54e-05	173	89	5	3aa1d28d4814798a772808ed29e1dbbdf92abd03
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)\|368C / Donor, Lineage, Cell class and subclass (all cells)	PLLP ST8SIA6 PIK3C2B LRRC32 SLC52A3	2.54e-05	173	89	5	22200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL13 ADGRG3 RHBDL2 ST8SIA6 HS3ST1	2.54e-05	173	89	5	53e97835d7a518c278e7b90a0734eb0095d6aa33
ToppCell	droplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL13 ADGRG3 RHBDL2 ST8SIA6 CTSG	2.54e-05	173	89	5	117163c5cd2b7aaa1c0682c8ac44b4249df4d2f8
ToppCell	droplet-Lung-LUNG-1m-Myeloid-basophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IL13 ADGRG3 RHBDL2 ST8SIA6 HS3ST1	2.54e-05	173	89	5	889a880de5fc19d26b82cfef3067869a28ef17ca
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CTSC ZG16B MUC5B BACE2 HS3ST1	2.54e-05	173	89	5	e8afef5ae68983eb8d6515b43952636a47e9d3d4
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PLLP IGFBP4 ST8SIA6 PIK3C2B LRRC32	2.54e-05	173	89	5	3a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell	droplet-Lung-1m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IL13 ADGRG3 RHBDL2 ST8SIA6 CTSG	2.54e-05	173	89	5	01df9baeedf30e3a4891738554cdd300394dbb96
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-Myeloid-CLC+_Mast_cell\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL13 ST8SIA6 BACE2 HS3ST1 CTSG	2.61e-05	174	89	5	36080fa12497faa752ff07ae52cd3864053eafef
ToppCell	NS-moderate-d_07-13-Lymphoid-NK\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FRZB LRRC32 CCDC3 SLC9B2 LAMC3	2.68e-05	175	89	5	f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCell	Control-Myeloid-Mast\|Myeloid / Disease state, Lineage and Cell class	IL13 ST8SIA6 TPSG1 BACE2 CTSG	2.75e-05	176	89	5	0c5916d63e1ada09105e46d2429b75129b7329ec
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC6A6 ST8SIA6 BACE2 HS3ST1 CTSG	2.75e-05	176	89	5	183ba1aa5cf594b88ec08e0e41241668b51256a9
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NRXN3 ZG16B MUC5B BACE2 HS3ST1	2.83e-05	177	89	5	779ba86f53650772755b52460be03f18bb204e55
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.6.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLCO2B1 CTSC AGRP VSIG4 PLA2G15	2.83e-05	177	89	5	929cd8f530ce001623735da53b7278d02522e2b5
ToppCell	nucseq-Epithelial-Epithelial_Airway-Secretory/RAS-Secretory\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NRXN3 ZG16B MUC5B BACE2 HS3ST1	2.83e-05	177	89	5	0f210cfb61b873c5fd77dc17eadf4d017306500e
ToppCell	3'-Parenchyma_lung-Immune_Myeloid_mast-Myeloid_Mast/Baso-mast_cell-Mast_cells-Mast_cells_L.1.4.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	IL13 MAGEB2 TPSG1 BACE2 CTSG	2.99e-05	179	89	5	9dd8d19050223cdebec2579014892b759e5e9de8
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IGFBP4 FRZB LRRC32 CCDC3 LAMC3	3.07e-05	180	89	5	64956a85c404a2ea7e4eaf6f95ebcc52c198b7cc
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 NRXN3 BACE2 HS3ST1 SLC52A3	3.15e-05	181	89	5	cef034030e6b029a49ae56be37ea1fac1a5c350e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IGFBP4 FRZB LRRC32 CCDC3 LAMC3	3.23e-05	182	89	5	fc4a5bf784705efe7965ce43ac23c2a8e602e90a
ToppCell	hematopoetic_progenitors-CD34+_MEP_2\|World / Lineage and Cell class	ST8SIA6 CALR TPSG1 BACE2 CTSG	3.23e-05	182	89	5	a7e7aa10f14111a6c7ba22e0f1668dcaa124714d
ToppCell	Control-Epithelial-Goblet\|Epithelial / Disease state, Lineage and Cell class	CTSC ZG16B MUC5B BACE2 HS3ST1	3.32e-05	183	89	5	bdd461349a1ef43a015843937d26e8d3571ecc22
ToppCell	3'_v3-lymph-node_spleen-Mast\|lymph-node_spleen / Manually curated celltypes from each tissue	IL13 TPSG1 BACE2 HS3ST1 CTSG	3.40e-05	184	89	5	83675c7a083c52fb74dc8b9d35df0ef69715f707
ToppCell	IPF-Myeloid-Mast\|IPF / Disease state, Lineage and Cell class	IL13 ST8SIA6 TPSG1 BACE2 CTSG	3.40e-05	184	89	5	c3baf21f10b45cf91ac99997a59f353bcf3de8b7
ToppCell	Control-Myeloid-Macrophage_Alveolar\|World / Disease state, Lineage and Cell class	SLCO2B1 CTSC AGRP VSIG4 PLA2G15	3.49e-05	185	89	5	85cb81759589a26d83676cffbf2bc37399683c10
ToppCell	(4)_Mast_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	IL13 TPSG1 BACE2 HS3ST1 CTSG	3.49e-05	185	89	5	c91e1081e630a61c18f6af6d198bfcf296746852
ToppCell	(4)_Mast_cells\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	IL13 TPSG1 BACE2 HS3ST1 CTSG	3.49e-05	185	89	5	3dd5d2237ab50b13a41c12f85e1b79cd72ea567b
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP21A2 ZG16B MUC5B BACE2 HS3ST1	3.59e-05	186	89	5	55fe25f4d0f2bc0fd4802a0a375169f2c41472fc
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	PLLP IGFBP4 ST8SIA6 PIK3C2B LRRC32	3.68e-05	187	89	5	a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 RPN1 CALR MFSD13A CTSG	3.77e-05	188	89	5	7e27e49ec1eb02fb74c86ec2ccb84751bc778b21
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PLLP IGFBP4 ST8SIA6 PIK3C2B LRRC32	3.77e-05	188	89	5	366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCell	PCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	PLLP ST8SIA6 PIK3C2B SLCO2B1 LRRC32	3.77e-05	188	89	5	b66f1f08827dd6c48583d871f9f33ea41e48bfb2
ToppCell	droplet-Marrow-nan-21m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADGRG3 RPN1 CALR MFSD13A CTSG	3.77e-05	188	89	5	4b14c3ad80507245564d5be96d33fd9361f67dd0
ToppCell	myeloid-macrophage\|myeloid / Lineage and Cell class	IGFBP4 SLCO2B1 VSIG4 BACE2 PLA2G15	3.87e-05	189	89	5	7c7dc5361250d6848c4050f8ef995561a0984a44
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADIPOQ IGFBP4 LRRC32 LAMC3 CHGB	3.87e-05	189	89	5	9e1a51997ef9b6999d9b40cf0a55e561e3b4a84c
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-Mast_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IL13 MAGEB2 BACE2 HS3ST1 CTSG	3.87e-05	189	89	5	7bc6e152fb4fe5cd6db9407929c15843a5d8f8c4
ToppCell	tumor_Lung-MAST_cells-MAST\|tumor_Lung / Location, Cell class and cell subclass	IL13 TPSG1 BACE2 HS3ST1 CTSG	3.87e-05	189	89	5	cd977962e01756b663728dae32ab9aba15bf7e22
ToppCell	Macrophages-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	CD4 SLCO2B1 CTSC OVCH1 PLA2G15	3.87e-05	189	89	5	c05b4b565c0ce56dbb45fc9503654a2ec1a7e1e9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CARTPT ST8SIA6 PIK3C2B CCDC3 OVCH1	3.87e-05	189	89	5	12b6f1c3bf526b90e112374bf937701f645c5780
Drug	A80a	CTSC TPSG1 BACE2 CTSG	9.19e-07	20	87	4	CID005487000
Drug	NH4Cl	CD4 SLC9A5 ARSA CTSC CHGB CTSG SLC4A9	6.81e-06	184	87	7	CID000025517
Disease	non-alcoholic fatty liver disease (is_marker_for)	IL13 ADIPOQ TLR9	6.20e-05	27	84	3	DOID:0080208 (is_marker_for)
Disease	Inherited obesity	CARTPT AGRP	3.55e-04	10	84	2	cv:C4054476
Disease	Obesity	CARTPT AGRP	3.55e-04	10	84	2	cv:C0028754
Disease	OBESITY	CARTPT AGRP	3.55e-04	10	84	2	601665
Disease	allergic conjunctivitis (is_marker_for)	IL13 TLR9	3.55e-04	10	84	2	DOID:11204 (is_marker_for)
Disease	ovarian carcinoma, COVID-19	WNT3 SURF4	4.33e-04	11	84	2	EFO_0001075, MONDO_0100096
Disease	Papillary Renal Cell Carcinoma	IL13 ADIPOQ LMAN2L UNC5C	4.98e-04	128	84	4	C1306837
Disease	Renal Cell Carcinoma	IL13 ADIPOQ LMAN2L UNC5C	4.98e-04	128	84	4	C0007134
Disease	Sarcomatoid Renal Cell Carcinoma	IL13 ADIPOQ LMAN2L UNC5C	4.98e-04	128	84	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	IL13 ADIPOQ LMAN2L UNC5C	4.98e-04	128	84	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	IL13 ADIPOQ LMAN2L UNC5C	4.98e-04	128	84	4	C1266044
Disease	rosacea severity measurement	IL13 NRXN3 RNF217 KCNK7	8.38e-04	147	84	4	EFO_0009180
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	IL13 ADIPOQ LMAN2L UNC5C	8.59e-04	148	84	4	C0279702
Disease	Dermatitis	IL13 DSG1	9.36e-04	16	84	2	C0011603
Disease	Keratoderma, Palmoplantar	DSG1 CTSC	9.36e-04	16	84	2	C4551675
Disease	congenital myasthenic syndrome (implicated_via_orthology)	CHRNE CHRNG	9.36e-04	16	84	2	DOID:3635 (implicated_via_orthology)
Disease	sinusitis (is_marker_for)	MUC5B TLR9	1.19e-03	18	84	2	DOID:0050127 (is_marker_for)
Disease	cardiovascular system disease (is_implicated_in)	ADIPOQ TLR9	1.62e-03	21	84	2	DOID:1287 (is_implicated_in)
Disease	Myocardial Ischemia	SLC6A6 ADIPOQ CALR CTSC	1.63e-03	176	84	4	C0151744
Disease	Dystonia	ARSA TOR1A SLC46A1	1.92e-03	86	84	3	C0013421
Disease	generalized anxiety disorder	LAMC3 HS3ST1	1.95e-03	23	84	2	EFO_1001892
Disease	corpus collosum mid-posterior volume measurement	VLDLR TMEM190	2.30e-03	25	84	2	EFO_0010300
Disease	atopic asthma	IL13 IGFBP4 LRRC32 PLA2G15	2.54e-03	199	84	4	EFO_0010638
Disease	Obesity	CARTPT VLDLR ADIPOQ AGRP	2.83e-03	205	84	4	C0028754

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLLALPATRGAQMGL	AGRP	11	O00253
VGSALLLLMLLVLLG	MAMDC4	1156	Q6UXC1
MGALARALLLPLLAQ	BACE2	1	Q9Y5Z0
FPLMLLGLVGVRKAL	SLC4A9	911	Q96Q91
MLLLGAVLLLLALPG	ADIPOQ	1	Q15848
MHGGQGPLLLLLLLA	CHRNG	1	P07510
MAPLLLQLAVLGAAL	ALG5	1	Q9Y673
MRLLLALLGVLLSVP	FGFR4	1	P22455
MALRKGGLALALLLL	IGFALS	1	P35858
MATPRGLGALLLLLL	ADGRG3	1	Q86Y34
MHLLLFQLLVLLPLG	CER1	1	O95813
MARAPLGVLLLLGLL	CHRNE	1	Q04844
GLGLQLLVQLVPLMQ	MUC5B	531	Q9HC84
GLLPDGLLFLLLLLM	PLA2G15	11	Q8NCC3
GLLFLLLLLMLLADP	PLA2G15	16	Q8NCC3
LLLLMLLADPALPAG	PLA2G15	21	Q8NCC3
RLGALMLLQLVLGLL	PLLP	36	Q9Y342
LRLLPMLGLLQLLAE	GPR107	21	Q5VW38
MLGLLQLLAEPGLGR	GPR107	26	Q5VW38
GNLGMILLIAVSPLL	OR8D1	41	Q8WZ84
LIGNIGLMLLIRIDP	OR5I1	41	Q13606
LLLLLLLLGSMAGYG	LRCOL1	11	A6NCL2
GLLLIPAVLIGMLEK	SLC46A1	431	Q96NT5
MLLATLLLLLLGGAL	LRP10	1	Q7Z4F1
RKLLMPLLGVIFLNG	MAGEB2	201	O15479
DGPLQGLQTLLLMVL	GPAA1	281	O43292
SMVLGSLLALLLPLG	FICD	31	Q9BVA6
LALLGYLLLGLLAML	KCNK7	236	Q9Y2U2
MLLLGLLLLPLLAGA	CYP21A2	1	P08686
LLLLAAMLLGNPGLV	GNLY	6	P22749
LLGLCLGLEFMGLPN	NRXN3	21	Q9Y4C0
NPLLLALGLMALLLT	IL13	6	P35225
LVALLLLGLPANGLM	GPR152	36	Q8TDT2
MLLLLLLLGSGQGPQ	LMAN2L	26	Q9H0V9
MGAPRSLLLALAAGL	ARSA	1	P15289
IGNGMELLRLPGLIL	TMEM63A	566	O94886
IGLLIMGFLVLGLVP	DSG1	551	Q02413
LNLLGLMLSCGIPEL	PIK3C2B	1276	O00750
MPVIAGGILAALLLL	FAM24B	1	Q8N5W8
LVLFGVPALLMRLDG	HHAT	301	Q5VTY9
MRPQILLLLALLTLG	LRRC32	1	Q14392
LLGLPSALAGMQDLR	RBBP8NL	336	Q8NC74
MRPLLVLLLLGLAAG	C1QTNF5	1	Q9BXJ0
MALGLLIAVPLLLQA	C1QL2	1	Q7Z5L3
MLRQLLLAALCLAGP	CCDC3	1	Q9BQI4
RILVNLLLDTLPMLG	CACNA1I	196	Q9P0X4
LLLDTLPMLGNVLLL	CACNA1I	201	Q9P0X4
MVLAAPLLLGFLLLA	GDF11	1	O95390
QDALLLLLMGLGPLL	C20orf141	131	Q9NUB4
MGAGPSLLLAALLLL	CTSC	1	P53634
MLLSVPLLLGLLGLA	CALR	1	P27797
PMALIVLGGVAGLLL	CD4	396	P01730
VRLLPLLGAALLLML	CARTPT	6	Q16568
LLGAALLLMLPLLGT	CARTPT	11	Q16568
MQPLLLLLAFLLPTG	CTSG	1	P08311
AMIAGLALLRNPELL	METTL13	476	Q8N6R0
MQPTLLLSLLGAVGL	CHGB	1	P05060
LKLGLSLLMLLAGPD	MFSD13A	341	Q14CX5
PLRAGQNILLLVLAM	CDH16	406	O75309
MGGLILVIPFLLILG	OR1E2	211	P47887
MAALLLGAVLLVAQP	HS3ST1	1	O14792
LALADMFLGLLVLPL	TAAR5	76	O14804
MALGACGLLLLLAVP	TPSG1	1	Q9NRR2
MLLVLLVRGLTLPGA	SLC6A6	256	P31641
VQLGSLLGALLMFPL	SLC52A3	436	Q9NQ40
ILGNLCMQLVLGIPL	RHBDL2	136	Q9NX52
MLGLLVALLALGLAV	THEM6	1	Q8WUY1
MGLLASAGLLLLLVI	OVCH1	1	Q7RTY7
APLLGGRLLLMDIVD	RNF215	86	Q9Y6U7
LLGMLLAGFLIRNIP	SLC9B2	146	Q86UD5
MEAPAAGLFLLLLLG	RPN1	1	P04843
MRPGGALLALLASLL	ST8SIA6	1	P61647
MLRAALSLLALPLAG	SLC9A5	1	Q14940
FLMRNLALGGGLLLL	SURF4	116	O15260
APLIMVLGLALGAIA	RNF217	501	Q8TC41
MLPLCLVAALLLAAG	IGFBP4	1	P22692
LLLGGGLMLAITLLE	SLC39A5	516	Q6ZMH5
LALMSPLGLAVGLAV	SLC39A2	231	Q9NP94
AMNLGIRLGLDPKLL	HIBADH	226	P31937
AMLLLLTLALLGGPT	ZG16B	36	Q96DA0
GFLELLAGLLLVMGP	TMEM35B	66	Q8NCS4
MKLGRAVLGLLLLAP	TOR1A	1	O14656
MLGCGIPALGLLLLL	TMEM190	1	Q8WZ59
LSLLAVALGLGVPML	TLR9	821	Q9NR96
GAILVALAGLLMTLP	SLCO2B1	121	O94956
PGGMLLLRAGLLALA	FRZB	6	Q92765
MEPHLLGLLLGLLLG	WNT3	1	P56703
SLLGLLLLGLMAFLI	SCART1	911	Q4G0T1
MGILLGLLLLGHLTV	VSIG4	1	Q9Y279
MGLTLLLLLLLGLEG	TREML1	1	Q86YW5
GQPHLGLQMLLLALN	UPK3B	6	Q9BT76
LGYLLQMLVLPALAL	UNC5C	16	O95185
AILPLLLLVMAAVGG	VLDLR	801	P98155
MAAAALLLGLALLAP	LAMC3	1	Q9Y6N6