Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmetalloendopeptidase activity

ADAMTS10 PAPPA2 OMA1 ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

1.88e-131206611GO:0004222
GeneOntologyMolecularFunctionmetallopeptidase activity

ADAMTS10 PAPPA2 OMA1 ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

5.13e-112006611GO:0008237
GeneOntologyMolecularFunctionendopeptidase activity

ADAMTS10 PAPPA2 OMA1 USP30 USP13 ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

1.30e-094306613GO:0004175
GeneOntologyMolecularFunctionpeptidase activity

ADAMTS10 PAPPA2 OMA1 USP30 USP13 ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7 USP21

2.28e-086546614GO:0008233
GeneOntologyMolecularFunctiontransition metal ion binding

PAPPA2 IFIH1 USP13 CRYZ ADAMTS3 ADAMTS2 CYP8B1 MMP23B CP ADAM30 ADAM33 DTX2 MMP7 DYRK2

2.73e-0511896614GO:0046914
GeneOntologyMolecularFunctionzinc ion binding

PAPPA2 IFIH1 USP13 CRYZ ADAMTS3 ADAMTS2 MMP23B ADAM30 ADAM33 DTX2 MMP7

1.49e-048916611GO:0008270
GeneOntologyBiologicalProcesscollagen catabolic process

ADAMTS3 ADAMTS2 MMP23B ADAMTS14 MMP7

7.33e-0753665GO:0030574
GeneOntologyBiologicalProcessprotein K6-linked deubiquitination

USP30 USP13

3.02e-053662GO:0044313
GeneOntologyBiologicalProcesscollagen fibril organization

ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

1.03e-0476664GO:0030199
GeneOntologyBiologicalProcesscollagen metabolic process

ADAMTS3 ADAMTS2 MMP23B ADAMTS14 MMP7

1.12e-04148665GO:0032963
GeneOntologyBiologicalProcessextracellular matrix organization

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAMTS14 MMP7

1.99e-04377667GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAMTS14 MMP7

2.02e-04378667GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAMTS14 MMP7

2.05e-04379667GO:0045229
GeneOntologyBiologicalProcessmitochondrial fusion

OMA1 USP30 PID1

2.25e-0437663GO:0008053
MousePhenoincreased spleen weight

PAPPA2 SPTA1 CIAO2B PFKM RYR2 USP21 MGRN1

3.09e-05254507MP:0004952
DomainZINC_PROTEASE

ADAMTS10 PAPPA2 OMA1 ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

2.76e-14986411PS00142
DomainMetalloPept_cat_dom

ADAMTS10 PAPPA2 ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

1.66e-13816410IPR024079
Domain-

ADAMTS10 PAPPA2 ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

1.66e-138164103.40.390.10
DomainPeptidase_M12B_N

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAM30 ADAM33 ADAMTS14

5.58e-1139647IPR002870
DomainPep_M12B_propep

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAM30 ADAM33 ADAMTS14

5.58e-1139647PF01562
DomainDISINTEGRIN_1

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAM30 ADAM33 ADAMTS14

6.75e-1140647PS00427
DomainReprolysin

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAM30 ADAM33 ADAMTS14

6.75e-1140647PF01421
DomainADAM_MEPRO

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAM30 ADAM33 ADAMTS14

6.75e-1140647PS50215
DomainDISINTEGRIN_2

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAM30 ADAM33 ADAMTS14

6.75e-1140647PS50214
DomainPeptidase_M12B

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAM30 ADAM33 ADAMTS14

6.75e-1140647IPR001590
DomainDisintegrin_dom

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAM30 ADAM33 ADAMTS14

8.12e-1141647IPR001762
DomainPLAC

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

4.51e-0919645PS50900
DomainPLAC

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

4.51e-0919645IPR010909
DomainPept_M10_metallopeptidase

ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

7.03e-0943646IPR001818
DomainADAM_spacer1

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

1.29e-0823645IPR010294
DomainADAM_spacer1

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

1.29e-0823645PF05986
DomainPeptidase_M12B_ADAM-TS

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

1.63e-0824645IPR013273
DomainCYSTEINE_SWITCH

ADAMTS7 ADAM30 ADAM33 ADAMTS14 MMP7

2.75e-0741645PS00546
DomainTSP_1

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

2.43e-0663645PF00090
DomainTSP1

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

2.84e-0665645SM00209
DomainTSP1_rpt

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

2.84e-0665645IPR000884
DomainTSP1

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

2.84e-0665645PS50092
DomainBromodomain_CS

BRPF1 ATAD2B TAF1L

9.43e-0526643IPR018359
DomainACR

ADAM30 ADAM33 ADAMTS14

1.06e-0427643SM00608
DomainADAM_Cys-rich

ADAM30 ADAM33 ADAMTS14

1.06e-0427643IPR006586
DomainBROMODOMAIN_1

BRPF1 ATAD2B TAF1L

2.74e-0437643PS00633
DomainBromodomain

BRPF1 ATAD2B TAF1L

2.97e-0438643PF00439
DomainBROMODOMAIN_2

BRPF1 ATAD2B TAF1L

3.73e-0441643PS50014
DomainBROMO

BRPF1 ATAD2B TAF1L

4.00e-0442643SM00297
DomainBromodomain

BRPF1 ATAD2B TAF1L

4.00e-0442643IPR001487
Domain-

BRPF1 ATAD2B TAF1L

4.00e-04426431.20.920.10
DomainDisintegrin_CS

ADAM30 ADAM33

1.34e-0316642IPR018358
DomainUSP_CS

USP30 USP13 USP21

1.51e-0366643IPR018200
DomainADAM_CR

ADAM30 ADAM33

1.71e-0318642PF08516
DomainUSP_1

USP30 USP13 USP21

1.78e-0370643PS00972
DomainUCH

USP30 USP13 USP21

1.86e-0371643PF00443
DomainUSP_2

USP30 USP13 USP21

1.86e-0371643PS00973
DomainUSP_3

USP30 USP13 USP21

1.93e-0372643PS50235
DomainUSP_dom

USP30 USP13 USP21

1.93e-0372643IPR028889
DomainPeptidase_C19_UCH

USP30 USP13 USP21

1.93e-0372643IPR001394
Domain-

ADAM30 ADAM33

2.11e-03206424.10.70.10
DomainDisintegrin

ADAM30 ADAM33

2.33e-0321642PF00200
DomainDISIN

ADAM30 ADAM33

2.33e-0321642SM00050
DomainM10A_MMP

MMP23B MMP7

2.79e-0323642IPR033739
DomainPept_M10A

MMP23B MMP7

2.79e-0323642IPR021190
DomainPeptidase_M10

MMP23B MMP7

3.04e-0324642PF00413
DomainZnMc

MMP23B MMP7

4.42e-0329642SM00235
DomainPeptidase_Metallo

MMP23B MMP7

4.42e-0329642IPR006026
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

2.66e-0739515M27417
PathwayREACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

2.66e-0739515MM15165
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

4.45e-0668515M27303
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

4.46e-05109515MM15164
PathwayREACTOME_O_LINKED_GLYCOSYLATION

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

4.87e-05111515M27416
PathwayREACTOME_COLLAGEN_FORMATION

ADAMTS3 ADAMTS2 ADAMTS14 MMP7

1.61e-0476514MM14573
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

1.62e-04143515M27275
PathwayREACTOME_COLLAGEN_FORMATION

ADAMTS3 ADAMTS2 ADAMTS14 MMP7

3.09e-0490514M631
Pubmed

ADAMTS: a novel family of extracellular matrix proteases.

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7

2.46e-091066411167130
Pubmed

The procollagen N-proteinases ADAMTS2, 3 and 14 in pathophysiology.

ADAMTS3 ADAMTS2 ADAMTS14

6.53e-09366325863161
Pubmed

Cloning and characterization of ADAMTS-14, a novel ADAMTS displaying high homology with ADAMTS-2 and ADAMTS-3.

ADAMTS3 ADAMTS2 ADAMTS14

6.53e-09366311741898
Pubmed

ADAMTS2 promotes radial migration by activating TGF-β signaling in the developing neocortex.

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS14

1.59e-081566438871984
Pubmed

Expression of ADAMTS-2, -3, -13, and -14 in culprit coronary lesions in patients with acute myocardial infarction or stable angina.

ADAMTS3 ADAMTS2 ADAMTS14

2.61e-08466322205175
Pubmed

Regulation of procollagen amino-propeptide processing during mouse embryogenesis by specialization of homologous ADAMTS proteases: insights on collagen biosynthesis and dermatosparaxis.

ADAMTS3 ADAMTS2 ADAMTS14

1.30e-07666316556917
Pubmed

O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

3.28e-077566520637190
Pubmed

Insights on ADAMTS proteases and ADAMTS-like proteins from mammalian genetics.

ADAMTS10 ADAMTS2 ADAMTS7

1.42e-061266325770910
Pubmed

Risk Association of TOX3 and MMP7 Gene Polymorphisms with Sporadic Breast Cancer in Mexican Women.

TOX3 MMP7

3.55e-06266235200585
Pubmed

Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function.

ADAMTS2 ADAMTS14

3.55e-06266237929635
Pubmed

Deltex2 represses MyoD expression and inhibits myogenic differentiation by acting as a negative regulator of Jmjd1c.

MYOD1 DTX2

3.55e-06266228351977
Pubmed

ADAMTS2 and ADAMTS14 can substitute for ADAMTS3 in adults for pro-VEGFC activation and lymphatic homeostasis.

ADAMTS2 ADAMTS14

3.55e-06266235316211
Pubmed

Spontaneous atopic dermatitis due to immune dysregulation in mice lacking Adamts2 and 14.

ADAMTS2 ADAMTS14

3.55e-06266229649548
Pubmed

ADAM-TS5, ADAM-TS6, and ADAM-TS7, novel members of a new family of zinc metalloproteases. General features and genomic distribution of the ADAM-TS family.

ADAMTS3 ADAMTS2 ADAMTS7

4.35e-061766310464288
Pubmed

Differential cleavage of lysyl oxidase by the metalloproteinases BMP1 and ADAMTS2/14 regulates collagen binding through a tyrosine sulfate domain.

ADAMTS2 ADAMTS14

1.06e-05366231152061
Pubmed

Induction of human ADAMTS-2 gene expression by IL-1α is mediated by a multiple crosstalk of MEK/JNK and PI3K pathways in osteoblast like cells.

ADAMTS3 ADAMTS2

1.06e-05366226232334
Pubmed

IL-6 upregulates a disintegrin and metalloproteinase with thrombospondin motifs 2 (ADAMTS-2) in human osteosarcoma cells mediated by JNK pathway.

ADAMTS3 ADAMTS2

1.06e-05366224752352
Pubmed

Activation of the beta myosin heavy chain promoter by MEF-2D, MyoD, p300, and the calcineurin/NFATc1 pathway.

MYOD1 MEF2D

2.12e-05466217111365
Pubmed

ADAMTS: a novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats.

ADAMTS3 ADAMTS2

2.12e-05466210094461
Pubmed

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components.

SLF2 ATAD2B

2.12e-05466224561620
Pubmed

Ubiquitin-specific peptidase 2a (USP2a) deubiquitinates and stabilizes β-catenin.

USP30 USP13 USP21

3.42e-053366330323974
Pubmed

Calcineurin initiates skeletal muscle differentiation by activating MEF2 and MyoD.

MYOD1 MEF2D

3.53e-05566212694204
Pubmed

USP21 negatively regulates antiviral response by acting as a RIG-I deubiquitinase.

IFIH1 USP21

3.53e-05566224493797
Pubmed

[ADAMTS family--new extracellular matrix degrading enzyme].

ADAMTS3 ADAMTS2

3.53e-05566211831030
Pubmed

A deregulated immune response to gliadin causes a decreased villus height in DQ8 transgenic mice.

ADAMTS2 MMP7

3.53e-05566219795413
Pubmed

Distinct protein arginine methyltransferases promote ATP-dependent chromatin remodeling function at different stages of skeletal muscle differentiation.

MYOD1 MEF2D

3.53e-05566219188441
Pubmed

Polymorphic variation within the ADAMTS2, ADAMTS14, ADAMTS5, ADAM12 and TIMP2 genes and the risk of Achilles tendon pathology: a genetic association study.

ADAMTS2 ADAMTS14

3.53e-05566223491141
Pubmed

Histone demethylase LSD1 is required to induce skeletal muscle differentiation by regulating myogenic factors.

MYOD1 MEF2D

3.53e-05566220833138
Pubmed

TRIM72, a novel negative feedback regulator of myogenesis, is transcriptionally activated by the synergism of MyoD (or myogenin) and MEF2.

MYOD1 MEF2D

5.29e-05666220399744
Pubmed

Histone recognition and large-scale structural analysis of the human bromodomain family.

ATAD2B TAF1L

7.40e-05766222464331
Pubmed

Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis.

MYOD1 MEF2D

7.40e-0576628026334
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

ADAMTS10 USP30 CRYZ ADAMTS2 PKD1L1 TONSL ADAMTS14 ZNF433 DYRK2 MGRN1

9.30e-051215661015146197
Pubmed

A genome-wide association study of early-onset breast cancer identifies PFKM as a novel breast cancer gene and supports a common genetic spectrum for breast cancer at any age.

TOX3 PFKM

9.86e-05866224493630
Pubmed

A disintegrin and metalloproteinase with thrombospondin motifs 2 cleaves and inactivates Reelin in the postnatal cerebral cortex and hippocampus, but not in the cerebellum.

ADAMTS3 ADAMTS2

1.27e-04966231491533
Pubmed

A genome wide association study (GWAS) providing evidence of an association between common genetic variants and late radiotherapy toxicity.

SEMA6D CNTNAP2

1.58e-041066224785509
Pubmed

Developmental deficits of MGE-derived interneurons in the Cntnap2 knockout mouse model of autism spectrum disorder.

ZIC4 CNTNAP2

1.58e-041066236819097
Pubmed

Transcription coactivator TRAP220 is required for PPAR gamma 2-stimulated adipogenesis.

MYOD1 THRAP3

1.93e-041166212037571
Pubmed

Skeletal muscle specification by myogenin and Mef2D via the SWI/SNF ATPase Brg1.

MYOD1 MEF2D

2.31e-041266216424906
Pubmed

Runx2-Twist1 interaction coordinates cranial neural crest guidance of soft palate myogenesis.

MYOD1 TFAP2B

4.18e-041666233482080
Pubmed

Matrix metalloproteinases in tumor invasion.

MMP23B MMP7

4.18e-041666210949577
Pubmed

Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.

ADAMTS10 SPTA1 CNTNAP2

5.57e-048466315203218
Pubmed

Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios.

TEP1 DYRK2

5.94e-041966214671302
Pubmed

Genome-wide association analyses identify 13 new susceptibility loci for generalized vitiligo.

IFIH1 SLC1A2

5.94e-041966222561518
Pubmed

Disruption of the mouse MRF4 gene identifies multiple waves of myogenesis in the myotome.

MYOD1 MEF2D

6.59e-04206627588068
Pubmed

Regulation of skeletal muscle sarcomere integrity and postnatal muscle function by Mef2c.

MYOD1 MEF2D

7.28e-042166217875930
Pubmed

Functional interactions between matrix metalloproteinases and glycosaminoglycans.

MMP23B MMP7

7.99e-042266223421805
Pubmed

Matrix metalloproteinases.

MMP23B MMP7

7.99e-042266210419448
Pubmed

Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes.

SYN2 ADAM30

7.99e-042266218372903
Pubmed

Genome-wide association study identifies five new breast cancer susceptibility loci.

TOX3 ANKRD16

7.99e-042266220453838
Pubmed

KLF13 is a genetic modifier of the Holt-Oram syndrome gene TBX5.

SEMA6D MEF2D

8.75e-042366228164238
Pubmed

Functional proteomics mapping of a human signaling pathway.

PAPPA2 USP13 MYOD1 PLCL2 PRDM4 RYR2

8.99e-0459166615231748
Pubmed

Myocardial Angiopoietin-1 Controls Atrial Chamber Morphogenesis by Spatiotemporal Degradation of Cardiac Jelly.

ADAMTS3 ADAMTS2

9.53e-042466229791855
Pubmed

Matrix metalloproteinases 2 and 9 are dispensable for pancreatic islet formation and function in vivo.

MMP23B MMP7

9.53e-042466215734845
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

RELCH SEMA6D DTX2

1.01e-0310366310819331
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

MYOD1 BRPF1 TOX3 TONSL ZBTB9 PRDM4 TFAP2B

1.35e-0387766720211142
Pubmed

The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.

TOX3 MMP7

1.39e-032966219094228
Pubmed

Ubiquitin Ser65 phosphorylation affects ubiquitin structure, chain assembly and hydrolysis.

USP30 USP21

1.59e-033166225527291
Pubmed

Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability.

USP30 BRPF1 BTAF1

1.64e-0312266331615875
Pubmed

OTUD6A Is an Aurora Kinase A-Specific Deubiquitinase.

USP13 USP21

1.70e-033266233669244
Pubmed

Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.

SLF2 ADNP2 ZBTB9

1.76e-0312566332891193
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

USP13 BTAF1 THRAP3 SBSN

1.80e-0327266431010829
GeneFamilyADAM metallopeptidases with thrombospondin type 1 motif

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS7 ADAMTS14

1.20e-091948550
GeneFamilyUbiquitin specific peptidases

USP30 USP13 USP21

4.41e-0456483366
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP23B MMP7

1.84e-0324482891
GeneFamilyADAM metallopeptidase domain containing|CD molecules

ADAM30 ADAM33

2.32e-032748247
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZIC4 ADNP2 ZBTB9 PRDM4 ZNF442 ZNF433

1.14e-0271848628
CoexpressionNABA_ECM_REGULATORS

ADAMTS10 PAPPA2 ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

4.26e-102386610M3468
CoexpressionNABA_ECM_REGULATORS

ADAMTS10 PAPPA2 ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

5.01e-102426610MM17062
CoexpressionNABA_MATRISOME_ASSOCIATED

ADAMTS10 PAPPA2 SEMA6D ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

2.15e-067386611MM17058
CoexpressionNABA_MATRISOME_ASSOCIATED

ADAMTS10 PAPPA2 SEMA6D ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

2.54e-067516611M5885
CoexpressionNABA_MATRISOME

ADAMTS10 PAPPA2 SEMA6D ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

3.99e-0510086611MM17056
CoexpressionNABA_MATRISOME

ADAMTS10 PAPPA2 SEMA6D ADAMTS3 ADAMTS2 ADAMTS7 MMP23B ADAM30 ADAM33 ADAMTS14 MMP7

4.68e-0510266611M5889
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 CNTNAP2 CP ADAMTS14 PID1

4.26e-0616266568c40d12689cc1b6c797e6e48173f0110f8144e4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 CNTNAP2 CP ADAMTS14 PID1

4.26e-06162665735fa3f77b31a4189e431d05c326403c18cbbffb
ToppCellAdult-Epithelial-lung_goblet_cell-D122|Adult / Lineage, Cell type, age group and donor

ADAMTS10 CYP8B1 TOX3 CP DTX2

4.94e-061676656efbb2ef6adc8da5dd67210969f825f5cc8ed022
ToppCelldroplet-Marrow-nan-3m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GVINP1 SPTA1 TOX3 ADAM33 TEP1

5.23e-061696655f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS2 SYN2 CP ADAM33 ADAMTS14

5.23e-06169665c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS3 ADAMTS2 MMP23B BICC1 RYR2

7.11e-0618066508ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS10 MMP23B ADAM33 BICC1 RYR2

7.70e-061836657eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 ADAMTS7 MMP23B CP BICC1

7.70e-061836657e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 ADAMTS7 MMP23B CP BICC1

7.70e-0618366563294d66e3ccf152ffe5d1237106764c14390b62
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 MMP23B CP PID1 BICC1

8.12e-06185665eaa54b76743628c89b4310be57b87fa92b75fd37
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 MMP23B CP PID1 BICC1

8.12e-06185665f7f4c921d248c637351e2e882589b99ba7f04b66
ToppCellfacs-Thymus-Epithelium-24m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 MMP23B CP PID1 BICC1

8.12e-06185665ff38a15af3dec36d9993f06623591872b5d1da9a
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D231|Adult / Lineage, Cell type, age group and donor

ADAMTS10 ADAMTS2 ADAM33 SLC1A2 BICC1

8.12e-06185665fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS10 ADAMTS2 MMP23B CP BICC1

8.34e-0618666535c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS10 ADAMTS2 MMP23B CP BICC1

8.34e-06186665d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 RELCH ATAD2B BICC1 RYR2

8.78e-061886656468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 RELCH ATAD2B BICC1 RYR2

8.78e-061886657a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

OMA1 RELCH ATAD2B BICC1 RYR2

8.78e-061886659cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellClub|World / shred by cell class for parenchyma

TOX3 CP DTX2 MMP7 TFAP2B

9.24e-061906651974d559d7fee6cb68065b18af8bd38b64910622
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS10 ADAMTS2 XIRP2 BICC1 RYR2

9.24e-0619066596a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 MLF1 PFKM RYR2

9.48e-06191665715f5b449b8e075959c05a5b38389df319663164
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 MLF1 PFKM RYR2

9.48e-06191665c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCelldroplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 MLF1 PFKM RYR2

9.72e-061926651a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCelldroplet-Heart-nan-24m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 MLF1 PFKM RYR2

9.72e-06192665f6a4e348406a852ace9fb21db8fbdff539217645
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS3 ADAMTS2 MMP23B BICC1 RYR2

9.72e-06192665deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS3 ADAM33 SLC1A2 PID1 BICC1

9.97e-06193665261cafc167c86ab277be4ea7f08b0173e2dde26e
ToppCellfacs-Lung-nan-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 MMP23B CP PID1 BICC1

9.97e-06193665d9c20a092b507c43fcf7ccb04073fecd27d1749c
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS2 ADAM33 SLC1A2 PID1 BICC1

1.05e-05195665ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCellfacs-Heart|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 MMP23B CP PID1 BICC1

1.10e-051976656a9571c0a3238b39214afdece93d7541bc8a0a70
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 PAPPA2 ADAMTS2 MMP23B ADAM33

1.10e-0519766526475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 PAPPA2 ADAMTS2 MMP23B ADAM33

1.10e-05197665155e63b33302a87393ace699b2f6d73abe9c5763
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADAMTS10 PAPPA2 ADAMTS2 MMP23B ADAM33

1.13e-051986650993d6895c0e4f360998ce35abea4ec3dd13e048
ToppCell15-Airway-Mesenchymal-Mesenchyme_SERPINF1-high|Airway / Age, Tissue, Lineage and Cell class

ADAMTS2 MMP23B ADAM33 PID1 BICC1

1.13e-051986653d76393e72eed59b4dd16130ef5dd1d331ba5711
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS10 TOX3 CP DTX2 MMP7

1.13e-05198665fab3135f03cf23a9f04f0eed543a9dc181f39f5f
ToppCellParenchymal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS10 TOX3 CP DTX2 MMP7

1.18e-05200665b992eeddee38e6fe3564e9b1850f6b20b89bf47d
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS2 MMP23B ADAM33 PID1 BICC1

1.18e-0520066574ad0ae592252060ee294d7483327d765a6ba1dd
ToppCellTracheal-10x5prime-Stromal-Fibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS2 MMP23B ADAM33 PID1 BICC1

1.18e-052006657ba292c30d915e66ebc8026fa76492cedf64700e
ToppCellCOVID-19-kidney-Epithelial_Doublet|kidney / Disease (COVID-19 only), tissue and cell type

ZIC4 SPTA1 CNTNAP2 RYR2

3.47e-05124664d6f59ddb9b9df02b5201f23fa5fb78f3fd891ee9
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ADAMTS10 CNTNAP2 ADAMTS14 PID1

6.05e-051436645a279da1cd8e63db32f7c85a73b493c2121d0a96
ToppCellTCGA-Brain-Recurrent_Tumor|TCGA-Brain / Sample_Type by Project: Shred V9

ADAMTS2 ADAMTS7 ADAMTS14 SBSN

6.05e-05143664eeb8ce6e051e18b82b74aaf2fc23f0cb87fc96d5
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ADAMTS10 CNTNAP2 ADAMTS14 PID1

6.39e-05145664997bd540c43725a85ca97e4b79ebe0d336860287
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS3 TOX3 PLCL2 SPAG16

6.74e-0514766464fa0753a3a79f492ef8acc6942bf90d379a983f
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-3|TCGA-Colorectal / Sample_Type by Project: Shred V9

ADAMTS7 FBXW5 MMP23B MGRN1

8.48e-05156664b464871ad7c8ce0d58013a27996639eac1e526d8
ToppCell390C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

USP13 CRYZ AACS SYN2

9.35e-051606648aaf6ac4f33ea291387fdbf9ff1a91d559391774
ToppCellfacs-Heart-RA-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 ADAM30 PFKM

9.81e-05162664593939be9d38690c89c31d4c58e351de26cbf9ab
ToppCellfacs-Heart-RA-3m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 ADAM30 PFKM

9.81e-051626643a61eda548afa2a41bdf6293d1050103dc210e52
ToppCellE16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_1|E16.5-samps / Age Group, Lineage, Cell class and subclass

ADAMTS2 CNTNAP2 CP PID1

1.00e-04163664f1ec2625b52664308968b01d8e0275e1e0751480
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEMA6D ADAMTS7 MMP23B ADAM33

1.08e-0416666449103b75c3e08656c5774f56fd00d7bd53eefcfb
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZIC4 CP TFAP2B BICC1

1.13e-041686649930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 ADAM33 SLC1A2 PID1

1.32e-04175664795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA2 ADAM33 TFAP2B SBSN

1.35e-041766648e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA2 ADAM33 TFAP2B SBSN

1.35e-04176664ed575330a08a6748ea4b28433292c8cfd157d444
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS10 XIRP2 THRAP3 RYR2

1.35e-04176664749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 MLF1 PFKM

1.38e-04177664692cd03bf0958ebeec34d41bfe87713a768e9a8e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM33 SLC1A2 PID1 RYR2

1.38e-041776649ec7f1e64312d26d434b3312b58386715dbad644
ToppCellfacs-Heart-RV-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 MLF1 PFKM

1.38e-04177664c08583ea68bbeb6b5de852a46b0c0f04792dae55
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZIC4 CP TFAP2B BICC1

1.38e-04177664599cf7f5b774e197a1b43c98e4b9a8c1a618f38a
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM33 SLC1A2 PID1 RYR2

1.38e-04177664016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

ADAMTS10 ADAMTS2 ADAMTS14 BICC1

1.41e-04178664142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 MLF1 PFKM

1.41e-0417866469f68eeab11b088fcb1f963c92eff0f1cd0e711a
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

TOX3 CP DTX2 TFAP2B

1.41e-0417866435a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)|390C / Donor, Lineage, Cell class and subclass (all cells)

TOX3 CP MMP7 TFAP2B

1.41e-04178664fce60ce6b662f1bdaa3b4da43800c6c22fe89533
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SYN2 ADAM33 BICC1 SBSN

1.41e-041786641e05bc26591fea16e29bcfc5f538dda1dc427f05
ToppCellMid-temporal_gyrus_(MTG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ADAMTS3 XIRP2 SYN2 PID1

1.41e-04178664ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCell390C-Epithelial_cells-Epithelial-G_(Club-Clara_cells)-|390C / Donor, Lineage, Cell class and subclass (all cells)

TOX3 CP MMP7 TFAP2B

1.41e-04178664b19c906e067b07eadfd68934d9330b447e24c708
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZIC4 ADAMTS2 MMP23B BICC1

1.47e-0418066439ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADAMTS3 ADAMTS2 MMP23B BICC1

1.47e-041806649b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellAT1-AT2_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MMP23B CNTNAP2 MMP7 BICC1

1.47e-041806643c7b2033821f9e34e2924bd8655f566edcbcc7d3
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS2 MMP23B PID1 BICC1

1.47e-041806649adebde5f4ca6dcb90e9113622862e14298465ac
ToppCellP28-Mesenchymal-mesenchymal_fibroblast|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS2 CP PID1 BICC1

1.50e-04181664091e7975badd1ffa463a8ec87908be20781ecfd6
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS2 MMP23B PID1 BICC1

1.54e-04182664e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCelldroplet-Limb_Muscle-nan-3m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 MLF1 PFKM

1.54e-04182664edfc598b7199ca1d8a399b264ab863c299b1eede
ToppCelldroplet-Kidney-nan-18m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 MLF1 CP MMP7

1.54e-04182664e3248d108b51c49ca2c978636e13017e23b53860
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PAPPA2 ADAM33 BICC1 SBSN

1.54e-041826649966f42c338cbd471efa8ffc765a6ce93693aa75
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS10 ADAMTS2 MMP23B BICC1

1.54e-04182664f4b74c2756989812abe4e7055ec8918f69d56025
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS3 TOX3 PLCL2 SPAG16

1.57e-04183664b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZIC4 CYP8B1 ADAM33 FAM9A

1.60e-041846649f524f0a1e7eb50e3b97a35c0ea7e183a4e99aa8
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS2 MMP23B PID1 BICC1

1.60e-0418466401257e5c12e38b849fd3d9496c43ded666249ba5
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 MMP23B ADAM33 BICC1

1.60e-04184664fea4fe648e9749177d0783443dc26a7df5807883
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PAPPA2 ADAM33 BICC1 SBSN

1.60e-04184664607b55022de21ddb6a2d75e085df76df7abf6624
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 MMP23B ADAM33 BICC1

1.60e-0418466496a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ZIC4 CYP8B1 ADAM33 FAM9A

1.60e-04184664779016341dbd6d54b5fdb8711692d31a9b2cec4b
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS2 MMP23B ADAM33 BICC1

1.60e-04184664780eb72da43527f0c72effac3423ec7384f05f20
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS2 ADAM33 SLC1A2 PID1

1.60e-04184664e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 USP13 SEMA6D TFAP2B

1.60e-04184664e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

USP30 SLC16A6 PKD1L1 TONSL

1.63e-04185664e06a784a297f357f3f8e761c24fa70722048ab42
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEMA6D ADAMTS14 RYR2 DYRK2

1.63e-04185664a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTS3 TOX3 PLCL2 SPAG16

1.63e-04185664d602a9b35e86e6f2a14a58e40fc4fb97f5fa3b08
ToppCelldroplet-Limb_Muscle-nan-24m-Mesenchymal-skeletal_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 MLF1 PFKM

1.63e-041856649245c322aae8bb9065d50dada198a5ee143a3444
ToppCellP03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

ADAMTS2 MMP23B PID1 BICC1

1.67e-04186664c0a036096c2cb23305605b8aaf18869d6e0fb512
ToppCell(0)_MSCs-(00)_Lepr-MSC|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ADAMTS2 MMP23B CP BICC1

1.67e-04186664f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell(0)_MSCs|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ADAMTS2 MMP23B CP BICC1

1.67e-04186664a832c1e0035bcd559722eccf262c145deb3494c7
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SEMA6D CNTNAP2 PID1 RYR2

1.67e-041866647def03dd856b765bd3f493288641981c4f7fd26e
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

ADAMTS2 MMP23B CP BICC1

1.67e-041866646ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCellfacs-Heart-Unknown-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 MLF1 RYR2

1.70e-041876640ffb988e0da2c7205c3515eca8e9851739bff5c5
ToppCellfacs-Heart-Unknown|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 MLF1 RYR2

1.70e-04187664362e56426a568423a81e8a30e3ecf99b76135843
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEMA6D ADAMTS14 RYR2 DYRK2

1.70e-04187664a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellfacs-Heart-Unknown-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP13 XIRP2 MLF1 RYR2

1.70e-04187664c004567767b89f3d89f5c7b28d952f3445957e1e
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

ADAMTS3 ADAM33 PID1 BICC1

1.74e-04188664706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

ADAMTS10 MMP23B ADAM33 MEF2D

1.74e-04188664c90669b51e1902fe7726555290c91c92a911df83
DiseaseCCL17 measurement, fetal genotype effect measurement, protein measurement

CYP8B1 PLCL2

1.34e-053632EFO_0004747, EFO_0007959, EFO_0009414
DiseaseCCL19 measurement, fetal genotype effect measurement, protein measurement

CYP8B1 PLCL2

1.34e-053632EFO_0004747, EFO_0007959, EFO_0009415
Diseasefetal genotype effect measurement, protein measurement, monokine induced by gamma interferon measurement

CYP8B1 PLCL2

1.34e-053632EFO_0004747, EFO_0007959, EFO_0008236
Diseasebody fat distribution

ADAMTS10 ADAMTS3 ADAMTS2 ADAMTS14 TFAP2B

7.29e-05202635EFO_0004341
DiseaseCCL17 measurement

CYP8B1 PLCL2

1.60e-049632EFO_0009414
DiseaseC-C motif chemokine 17 measurement

CYP8B1 PLCL2

2.92e-0412632EFO_0008045
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

OMA1 ZIC4 SEMA6D PLCL2 ZBTB9 BTAF1 TFAP2B RYR2

2.95e-04801638EFO_0003888, EFO_0007052, MONDO_0002491
Diseasekynurenic acid measurement

SEMA6D DYRK2

3.45e-0413632EFO_0010506
Diseaseglucose-dependent insulinotropic peptide measurement, glucose tolerance test

PAPPA2 ADAM30

4.02e-0414632EFO_0004307, EFO_0008464
Diseasebody surface area

ADAMTS10 PAPPA2 ADAMTS3 SLF2 ZBTB9 PRDM4 TFAP2B

4.34e-04643637EFO_0022196
Diseaseamygdala volume change measurement

LINC-PINT PKD1L1

5.28e-0416632EFO_0021490
Diseaseleptin measurement, type 2 diabetes mellitus

LINC-PINT SYN2

5.28e-0416632EFO_0005000, MONDO_0005148
Diseaselung carcinoma

SEMA6D ADAMTS7 SLF2 CYP8B1 LINC-PINT ZBTB9

5.70e-04482636EFO_0001071
Diseasemitochondrial DNA measurement

USP30 CNTNAP2 ZBTB9 MEF2D BICC1

6.83e-04328635EFO_0006312
DiseaseAntimigraine preparation use measurement

PID1 MEF2D

9.18e-0421632EFO_0009939
Diseasecarpal tunnel syndrome

ADAMTS10 ADAMTS14 PID1

9.24e-0489633EFO_0004143
Diseasesleep duration

OMA1 SEMA6D SPTA1 ZBTB9 ADAMTS14

1.06e-03362635EFO_0005271
Diseaseresponse to antineoplastic agent

TOX3 BRMS1L RYR2

1.26e-0399633GO_0097327
Diseaseinterleukin 5 measurement

CNTNAP2 SPAG16

1.64e-0328632EFO_0008185
Diseasecorneal topography

ADAMTS3 ADAMTS7 PKD1L1

1.66e-03109633EFO_0004345

Protein segments in the cluster

PeptideGeneStartEntry
HTKMSLHGASGGHER

BTBD10

46

Q9BSF8
HTAAMHGHLEAVKVL

ANKRD16

176

Q6P6B7
HLKEHLLHGNMTSSD

AACS

311

Q86V21
HHMGQSLSKEVAHVL

GVINP1

776

Q7Z2Y8
ATMAHEIGHSLGLSH

ADAM33

341

Q9BZ11
KMDVSHTEHSHVIGK

BICC1

136

Q9H694
AHEIGHTFGMNHDGV

ADAMTS10

391

Q9H324
IAHETGHVLGMEHDG

ADAMTS14

396

Q8WXS8
VAHETGHVLGMEHDG

ADAMTS2

406

O95450
MKGDAHPLHHDTAIL

ADAMTS7

326

Q9UKP4
HMEVAHKHSESKSGE

ADNP2

711

Q6IQ32
LHSAHHGLDAGMGDS

TFAP2B

151

Q92481
AHENIIHGSGATGKM

CRYZ

311

Q08257
GMGNEIDLHTVHFHG

CP

986

P00450
GEHGLDEHKLHMYLS

RELCH

736

Q9P260
AATHELGHSLGMGHS

MMP7

211

P09237
IHHKTEMDRNITGHG

DTX2

581

Q86UW9
SIGGLSHHIHALKEM

ATAD2B

401

Q9ULI0
HAHVLLAAFEKHMDG

MGRN1

216

O60291
DHVIDIHGHIIGMGL

FBXW5

396

Q969U6
HHLDHKGEATVHMDT

PID1

146

Q7Z2X4
VSHDGHDIMKQHCGE

LINC-PINT

61

A0A455ZAR2
MTHEEHHAAKTLGIG

PFKM

1

P08237
MHVGALLKPEEHSHF

MYOD1

51

P15172
EHTGIHTMKLEHIAA

FAM9A

111

Q8IZU1
GHTDTMIHEVGHVLG

PAPPA2

726

Q9BXP8
SAHELGHAVGMSHDE

ADAM30

336

Q9UKF2
VAHETGHVLGMEHDG

ADAMTS3

396

O15072
EKDGMHHTVTKHRGI

BTAF1

956

O14981
VRMHDSHLGSEEPKH

SLC1A2

16

P43004
SGEDIHVIEKMHHVN

IFIH1

916

Q9BYX4
MPVHSRGDKKETNHH

BRMS1L

1

Q5PSV4
GHTSVMTGSLLDDHH

CNTNAP2

261

Q9UHC6
NHGMDKVAHEINHGI

SBSN

91

Q6UWP8
AIMHHEGHMDDGISL

RYR2

391

Q92736
TIGGSKHTMNDHLHV

DYRK2

66

Q92630
HGADHSRTSLMGKSH

PKD1L1

2091

Q8TDX9
KMDVHITPGTHASEH

CIAO2B

116

Q9Y3D0
VQGDHEMIHSASTKH

CYP8B1

116

Q9UNU6
QAGKGLMHHLTEDHL

MEF2D

276

Q14814
TQKAHLESHMVIHTG

PRDM4

656

Q9UKN5
VILGMHSAEGHHKAF

OR6K6

251

Q8NGW6
MGLCQHHHSGETKVV

SLC16A6

476

O15403
GHAHSGMGKVKVENH

SYN2

271

Q92777
VHVAAHEIGHALGLM

MMP23B

206

O75900
FMLQHASGEHKDGHG

TAF1L

1811

Q8IZX4
AAMEFHEHLHSIGTK

PLCL2

1031

Q9UPR0
MKGVKEHHEDHGIHE

SLF2

116

Q8IX21
HAVLGHAAEKAGMVH

OMA1

331

Q96E52
GMHIPHSLAGDEATH

BRPF1

746

P55201
IDVHGTEMVSHLEKH

XIRP2

141

A4UGR9
HHVKEHHFGSSGMTL

THRAP3

636

Q9Y2W1
SDDKMAHHTLLLGSG

USP21

196

Q9UK80
MEKLHGHVSAHPDIL

TEP1

1

Q99973
VSLATTLGDMKDHHG

TONSL

356

Q96HA7
IHKLMGHENEAHTVV

SPAG16

596

Q8N0X2
DSDSGLEKMAIGHHI

MLF1

146

P58340
MGHSAHEETKAHIEE

SPTA1

121

P02549
DGVLHSSGLHMDQSH

TOX3

126

O15405
LTEHMKTHAGALHAC

ZBTB9

426

Q96C00
MHELVTHVTVEHVGG

ZIC4

151

Q8N9L1
FLRGHEKTHTGEKMH

ZNF442

586

Q9H7R0
VVVHHGDMHSGHFVT

USP30

441

Q70CQ3
QAMKSHSEKAHGHGA

SEMA6D

786

Q8NFY4
HLGMHTGEISHKCKI

ZNF433

356

Q8N7K0
DPHLAKHLAHFGIDM

USP13

281

Q92995