Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncalcium ion binding

CAPN9 TRPM2 OTOL1 JAG2 HMCN2 PLA2G4A BAIAP3 FBLN7 FAT4 PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 SLIT1 DCHS1 SCUBE3 MCTP2 AGRN CDH16

2.38e-0574918620GO:0005509
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

FBLN7 SLIT1 CHRD AGRN

1.44e-04291864GO:0043395
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

HMCN2 NECTIN2 FAT4 PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 PTPN23 DCHS1 CDH16

1.28e-0618718911GO:0007156
GeneOntologyBiologicalProcesssynapse assembly

EPHB3 RELN NRXN3 PPP1R9B GNPAT PCDHB10 PCDHB9 PCDHB6 PCDHB2 SHANK2 ELFN1 SLIT1 AGRN

5.63e-0630818913GO:0007416
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

HMCN2 NECTIN2 FAT4 PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 PTPN23 SCARF1 ELFN1 DCHS1 CDH16

6.70e-0631318913GO:0098742
GeneOntologyBiologicalProcesscalcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules

PCDHB10 PCDHB9 PCDHB6 PCDHB2 DCHS1 CDH16

8.78e-06531896GO:0016339
GeneOntologyBiologicalProcesssynapse organization

EPHB3 RELN NRXN3 HMCN2 GLRB PPP1R9B GNPAT PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 GRIN2B OPA1 SHANK2 ELFN1 SLIT1 CHRD AGRN

1.85e-0568518919GO:0050808
GeneOntologyBiologicalProcessolfactory bulb interneuron differentiation

UNCX ARX DICER1 SLIT1

8.72e-05261894GO:0021889
GeneOntologyBiologicalProcesscell junction organization

EPHB3 RELN NRXN3 HMCN2 GLRB PPP1R9B GNPAT PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 PTPN23 GRIN2B SHROOM2 OPA1 SHANK2 ELFN1 SLIT1 CHRD TRPV4 AGRN

8.93e-0597418922GO:0034330
GeneOntologyCellularComponentperoxisome

PEX6 DAO MFF GNPAT NUDT17 EHHADH CD33 AKAP11

1.25e-041621918GO:0005777
GeneOntologyCellularComponentmicrobody

PEX6 DAO MFF GNPAT NUDT17 EHHADH CD33 AKAP11

1.25e-041621918GO:0042579
DomainCadherin_CS

FAT4 PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 DCHS1 CDH16

1.24e-051091848IPR020894
DomainCADHERIN_1

FAT4 PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 DCHS1 CDH16

1.62e-051131848PS00232
DomainCadherin

FAT4 PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 DCHS1 CDH16

1.62e-051131848PF00028
DomainCADHERIN_2

FAT4 PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 DCHS1 CDH16

1.72e-051141848PS50268
Domain-

FAT4 PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 DCHS1 CDH16

1.72e-0511418482.60.40.60
DomainCA

FAT4 PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 DCHS1 CDH16

1.84e-051151848SM00112
DomainCadherin-like

FAT4 PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 DCHS1 CDH16

1.96e-051161848IPR015919
DomainCadherin

FAT4 PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2 DCHS1 CDH16

2.21e-051181848IPR002126
DomainEGF-like_dom

RELN JAG2 NRXN3 FCGBP HMCN2 FBLN7 FAT4 SCARF1 SLIT1 SCUBE3 AGRN

3.78e-0524918411IPR000742
DomainCadherin_C

PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

5.56e-05421845IPR032455
DomainCadherin_C_2

PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

5.56e-05421845PF16492
DomainEGF-type_Asp/Asn_hydroxyl_site

JAG2 NRXN3 HMCN2 FBLN7 FAT4 SLIT1 SCUBE3

8.61e-051061847IPR000152
Domaincwf21

U2SURP SRRM2

9.65e-0521842PF08312
DomainmRNA_splic_Cwf21_dom

U2SURP SRRM2

9.65e-0521842IPR013170
DomainEGF

RELN JAG2 NRXN3 FCGBP FBLN7 FAT4 SCARF1 SLIT1 SCUBE3 AGRN

1.16e-0423518410SM00181
DomainEGF_3

RELN JAG2 NRXN3 HMCN2 FBLN7 FAT4 SCARF1 SLIT1 SCUBE3 AGRN

1.16e-0423518410PS50026
DomainFol_N

FCGBP SLIT1 AGRN

1.46e-04111843IPR003645
DomainEphrin_rec_like

EPHB3 TG SCUBE3

1.46e-04111843PF07699
DomainFOLN

FCGBP SLIT1 AGRN

1.46e-04111843SM00274
DomainGrowth_fac_rcpt_

EPHB3 JAG2 HMCN2 FAT4 HTRA3 SCARF1 SLIT1 SCUBE3

1.60e-041561848IPR009030
DomainEGF_CA

JAG2 HMCN2 FBLN7 FAT4 SLIT1 SCUBE3 AGRN

2.08e-041221847SM00179
DomainEGF_1

RELN JAG2 NRXN3 HMCN2 FBLN7 FAT4 SCARF1 SLIT1 SCUBE3 AGRN

2.26e-0425518410PS00022
DomainEGF-like_Ca-bd_dom

JAG2 HMCN2 FBLN7 FAT4 SLIT1 SCUBE3 AGRN

2.29e-041241847IPR001881
DomainEGF-like_CS

RELN JAG2 NRXN3 HMCN2 FBLN7 FAT4 SCARF1 SLIT1 SCUBE3 AGRN

2.72e-0426118410IPR013032
DomainSec16_C

SEC16A SEC31A

2.88e-0431842PF12931
DomainASD1

SHROOM2 SHROOM1

2.88e-0431842PF08688
DomainASD1_dom

SHROOM2 SHROOM1

2.88e-0431842IPR014800
DomainASD1

SHROOM2 SHROOM1

2.88e-0431842PS51306
DomainACE1_Sec16_Sec31

SEC16A SEC31A

2.88e-0431842IPR024298
DomainEGF_2

RELN JAG2 NRXN3 HMCN2 FBLN7 FAT4 SCARF1 SLIT1 SCUBE3 AGRN

3.07e-0426518410PS01186
DomainEGF_Ca-bd_CS

JAG2 HMCN2 FBLN7 FAT4 SLIT1 SCUBE3

3.96e-04971846IPR018097
DomainEGF_CA

JAG2 HMCN2 FBLN7 FAT4 SLIT1 SCUBE3

4.42e-04991846PS01187
DomainCadherin_2

PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

4.50e-04651845PF08266
DomainCadherin_N

PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

4.50e-04651845IPR013164
DomainASX_HYDROXYL

JAG2 NRXN3 HMCN2 FBLN7 FAT4 SCUBE3

4.67e-041001846PS00010
DomainLAM_G_DOMAIN

NRXN3 FAT4 SLIT1 AGRN

5.18e-04381844PS50025
DomainShroom_fam

SHROOM2 SHROOM1

5.72e-0441842IPR027685
DomainASD2_dom

SHROOM2 SHROOM1

5.72e-0441842IPR014799
DomainASD2

SHROOM2 SHROOM1

5.72e-0441842PF08687
DomainPeptidase_S1C

HTRA2 HTRA3

5.72e-0441842IPR001940
DomainASD2

SHROOM2 SHROOM1

5.72e-0441842PS51307
DomainPDZ_2

HTRA2 HTRA3

5.72e-0441842PF13180
DomainLamG

NRXN3 FAT4 SLIT1 AGRN

9.10e-04441844SM00282
DomainEGF

JAG2 NRXN3 FBLN7 SLIT1 SCUBE3 AGRN

1.56e-031261846PF00008
DomainEGF_CA

JAG2 HMCN2 FBLN7 FAT4 SCUBE3

1.61e-03861845PF07645
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SPEG PEX6 BCL9 STK11IP JAG2 TBC1D16 PNPLA6 FAM83F RRP12 SEC16A RIPOR1 BRAT1 DOCK6 HECTD1 KHNYN SOCS3 FBRSL1 LRRK1 PKMYT1 CPTP AATK SHANK2 CTDP1 HELZ2 NPRL3 AGRN CEP170B

1.20e-1011051932735748872
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SPEG BCL11A NCDN RRP12 SEC16A RIPOR1 CAMTA1 BAIAP3 FNIP2 KHNYN RALGAPB OPA1 SLIT1 SELENOI SRRM2 CEP170B SON

1.55e-104071931712693553
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

CHD3 BCL9 PNPLA6 RRP12 SEC16A PLA2G4A RIPOR1 DHX29 CLUH NELFE RALGAPB YTHDC2 RFFL NSMCE3 SMTN CTDP1 HELZ2 SMARCC1 SRRM2 TOP2A SON

2.63e-097741932115302935
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

SEC16A CAMTA1 BAIAP3 RALGAPB PTPN23 SIK3 DICER1 AATK SLIT1 HELZ2 AKAP11

6.02e-082251931112168954
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

KCNH8 TRPM2 ASH1L CHD3 MAP3K12 NCDN JAG2 PNPLA6 KCNQ5 NECTIN2 ACSF3 PPP1R9B RIPOR1 CAMTA1 DOCK6 HECTD1 BAIAP3 ST7 B3GALNT2 RALGAPB FBRSL1 SHROOM2 NAALADL2 SHANK2 MCTP2 CEP170B EPB41

6.64e-0814891932728611215
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PABIR1 AARS1 EXPH5 MAST4 KCNQ5 NECTIN2 SEC16A DOCK6 HECTD1 NELFE IRS4 HIPK4 RALGAPB SIK3 VPS13D IPO9 AKAP11 SRRM2 CEP170B EPB41

8.23e-088611932036931259
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

NCDN PIP5KL1 PPP1R9B AGAP2 GRIA2 GRIN2B SIK3 OPA1 SHANK2 AKAP11 CEP170B

5.58e-072811931128706196
Pubmed

Protocadherins.

PCDHB10 PCDHB9 PCDHB6 PCDHB2

6.32e-0713193412231349
Pubmed

Clustered gamma-protocadherins regulate cortical interneuron programmed cell death.

RELN PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

7.75e-0757193632633719
Pubmed

CTCF Governs the Identity and Migration of MGE-Derived Cortical Interneurons.

RELN PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

8.60e-0758193630377227
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

AARS1 PRPF6 RRP12 PWP2 SEC16A HECTD1 CLUH IRS4 U2SURP YTHDC2 DICER1 ZCCHC3 HELZ2 SMARCC1 SRRM2 SON

8.65e-076531931622586326
Pubmed

CTDP1 regulates breast cancer survival and DNA repair through BRCT-specific interactions with FANCI.

PTPN9 PNPLA6 ACAD9 SHROOM2 OPA1 CTDP1 YME1L1

1.96e-06104193731240132
Pubmed

The human and murine protocadherin-beta one-exon gene families show high evolutionary conservation, despite the difference in gene number.

PCDHB10 PCDHB9 PCDHB6 PCDHB2

4.15e-0620193411322959
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ASH1L PEX6 CHD3 BCL11A PNPLA6 HMCN2 SEC16A FBRSL1 YTHDC2 SIK3 DICER1 OPA1 SMARCC1 SRRM2 IRX2 YME1L1 TOP2A CEP170B CDH16 SON

4.55e-0611161932031753913
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

PEX6 STK11IP MFF NECTIN2 SEC16A STX7 DOCK6 FNIP2 ST7 PKMYT1 VPS13D AKAP11 YME1L1

5.48e-065041931334432599
Pubmed

The functional interactome landscape of the human histone deacetylase family.

CHD3 PRPF6 BCL11A RRP12 SEC16A MIER2 DICER1 SMARCC1 SRRM2 SON

5.51e-062891931023752268
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

APC2 BCL11A BCL9 NCDN PTPN9 SEC16A PPP1R9B AGAP2 GRIA2 SEC31A GRIN2B SIK3 OPA1 SHANK2 DCHS1 SMARCC1 AGRN CEP170B

7.94e-069631931828671696
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PEX6 MFF TOMM22 RRP12 PWP2 SEC16A ACSF3 CLUH IRS4 NDUFAF5 HTRA2 ST7 ACAD9 YTHDC2 OPA1 ZCCHC3 PKMYT1 VPS13D AKAP11 SRRM2 YME1L1 TOP2A SON

1.05e-0514961932332877691
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

PRPF6 NCDN PTPN9 PWP2 CLUH GNPAT IRS4 ACAD9 SEC31A OPA1 IPO9 SMARCC1 TOP2A

1.67e-055601931335241646
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

PABIR1 EXPH5 PPP1R12B TRPM2 RRP12 SEC16A PPP1R9B IRS4 ACAD9 PTPN23 OPA1 CNNM3 SRRM2

2.12e-055731931328330616
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

AARS1 HS6ST2 NCDN JAG2 PNPLA6 TOMM22 RRP12 NECTIN2 STX7 BRAT1 HECTD1 ACAD9 SEC31A OPA1 CNNM3 IPO9 YME1L1

2.24e-059421931731073040
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

MAST4 SEC16A HECTD1 YTHDC2 DICER1 VPS13D AKAP11 CEP170B

2.37e-05209193836779422
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

AARS1 EXPH5 SPEG PRPF6 RRP12 ACAD9 U2SURP PCDHB9 PCDHB6 YTHDC2 OPA1 VPS13D

2.42e-054971931236774506
Pubmed

Intrafamilial "DOA-plus" phenotype variability related to different OMI/HTRA2 expression.

HTRA2 OPA1

3.06e-052193231609081
Pubmed

A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor.

EPOR SOCS3

3.06e-052193212027890
Pubmed

Asymmetric Action of STAT Transcription Factors Drives Transcriptional Outputs and Cytokine Specificity.

STAT1 SOCS3

3.06e-052193225992861
Pubmed

CD33 responses are blocked by SOCS3 through accelerated proteasomal-mediated turnover.

SOCS3 CD33

3.06e-052193217008544
Pubmed

Identification of new OPA1 cleavage site reveals that short isoforms regulate mitochondrial fusion.

OPA1 YME1L1

3.06e-052193233237841
Pubmed

Correction of sickle cell disease in adult mice by interference with fetal hemoglobin silencing.

EPOR BCL11A

3.06e-052193221998251
Pubmed

Regulators of calcineurin 1 deficiency attenuates tubulointerstitial fibrosis through improving mitochondrial fitness.

RCAN1 CDH16

3.06e-052193232896034
Pubmed

Giant cadherins Fat and Dachsous self-bend to organize properly spaced intercellular junctions.

FAT4 DCHS1

3.06e-052193225355906
Pubmed

Mitochondrial Optic Atrophy (OPA) 1 Processing Is Altered in Response to Neonatal Hypoxic-Ischemic Brain Injury.

OPA1 YME1L1

3.06e-052193226393574
Pubmed

Modulation of mitochondrial function and morphology by interaction of Omi/HtrA2 with the mitochondrial fusion factor OPA1.

HTRA2 OPA1

3.06e-052193220064504
Pubmed

SON and SRRM2 are essential for nuclear speckle formation.

SRRM2 SON

3.06e-052193233095160
Pubmed

Structure of the planar cell polarity cadherins Fat4 and Dachsous1.

FAT4 DCHS1

3.06e-052193236797229
Pubmed

Deletion of Dicer in late erythroid cells results in impaired stress erythropoiesis in mice.

EPOR DICER1

3.06e-052193224971698
Pubmed

Association between the methylation of the STAT1 and SOCS3 in peripheral blood and gastric cancer.

STAT1 SOCS3

3.06e-052193232108380
Pubmed

Mammalian cadherins DCHS1-FAT4 affect functional cerebral architecture.

FAT4 DCHS1

3.06e-052193225930014
Pubmed

ADAP restraint of STAT1 signaling regulates macrophage phagocytosis in immune thrombocytopenia.

STAT1 FYB1

3.06e-052193235637282
Pubmed

FAM122A maintains DNA stability possibly through the regulation of topoisomerase IIα expression.

PABIR1 TOP2A

3.06e-052193232866497
Pubmed

Proteolytic cleavage of Opa1 stimulates mitochondrial inner membrane fusion and couples fusion to oxidative phosphorylation.

OPA1 YME1L1

3.06e-052193224703695
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

AARS1 ASH1L STAT1 CLUH ST7 B3GALNT2 TUT1 SEC31A SIK3 NSMCE3 ZCCHC3 IPO9 ZFYVE19 DNAH11

3.42e-056891931436543142
Pubmed

Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously.

RELN ARX SLIT1

3.57e-0512193316540508
Pubmed

VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.

NCDN STAT1 PTPN9 RRP12 SEC16A BRAT1 PTPN23 SMARCC1 SON

3.63e-05288193923383273
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

PRPF6 RRP12 PWP2 SEC16A HECTD1 DHX29 IRS4 YTHDC2 DICER1 SMARCC1 TOP2A

3.88e-054401931134244565
Pubmed

Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.

PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

3.92e-0568193511230163
Pubmed

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca2+/CaM) and CaM Kinase II (CaMKII) Binding Partner.

AARS1 PPP1R12B PPP1R9B STX7 AGAP2 OPA1 TG IPO9

5.13e-05233193829518331
Pubmed

Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.

AARS1 PEX6 RRP12 PWP2 SEC16A RALGAPB TUT1 OPA1 VPS13D CTDP1 TOP2A

5.15e-054541931133226137
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

5.17e-0572193510380929
Pubmed

Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.

PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

5.90e-0574193510817752
Pubmed

Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.

PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

7.14e-0577193510835267
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

AARS1 PEX6 CHD3 NCDN GNPAT RALGAPB FBRSL1 YTHDC2 SIK3 DICER1 SMARCC1 ZBED1 AGRN

7.68e-056501931338777146
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

CHD3 RRP12 DHX29 YTHDC2 HELZ2 SRRM2 TOP2A SON

8.38e-05250193833536335
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PABIR1 PPP1R12B PTPN9 RRP12 NECTIN2 SEC16A PPP1R9B IRS4 RCAN1 ST7 RALGAPB PTPN23 OPA1 CNNM3 IPO9 SRRM2 YME1L1

8.43e-0510491931727880917
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

8.57e-0580193510716726
Pubmed

Large-scale concatenation cDNA sequencing.

SPATA2L STX7 DHX29 BAIAP3 GNPAT RCAN1 PCDHB10 DICER1 VPS13D IPO9 SHANK2 CHRD

8.71e-05568193129110174
Pubmed

Early Correction of N-Methyl-D-Aspartate Receptor Function Improves Autistic-like Social Behaviors in Adult Shank2-/- Mice.

GRIA2 GRIN2B SHANK2

8.93e-0516193330466882
Pubmed

Murine Creld1 controls cardiac development through activation of calcineurin/NFATc1 signaling.

EPOR CA9 RCAN1

8.93e-0516193324697899
Pubmed

Fat4-Dchs1 signalling controls cell proliferation in developing vertebrae.

FAT4 UNCX DCHS1

8.93e-0516193327381226
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

HS6ST2 PPP1R12B STK11IP PIGX PWP2 BRAT1 DOCK6 HECTD1 ACAD9 RALGAPB YTHDC2 SIK3 DICER1 SELENOI

8.95e-057541931433060197
Pubmed

Neuroanatomical distribution of ARX in brain and its localisation in GABAergic neurons.

RELN ARX

9.16e-053193214992814
Pubmed

MicroRNA-223 is neuroprotective by targeting glutamate receptors.

GRIA2 GRIN2B

9.16e-053193223112146
Pubmed

Obsessive-compulsive disorder, which genes? Which functions? Which pathways? An integrated holistic view regarding OCD and its complex genetic etiology.

GRIA2 GRIN2B

9.16e-053193228608743
Pubmed

Upregulation of the Suppressors of Cytokine Signaling 1 and 3 Is Associated with Arrest of Phosphorylated-STAT1 Nuclear Importation and Reduced Innate Response in Denguevirus-Infected Macrophages.

STAT1 SOCS3

9.16e-053193226709547
Pubmed

miR-2909 regulates ISGylation system via STAT1 signalling through negative regulation of SOCS3 in prostate cancer.

STAT1 SOCS3

9.16e-053193228622443
Pubmed

Increased suppressor of cytokine signaling-3 expression predicts mucosal relapse in ulcerative colitis.

STAT1 SOCS3

9.16e-053193222535619
Pubmed

Differential association of postsynaptic signaling protein complexes in striatum and hippocampus.

PPP1R9B GRIN2B

9.16e-053193223173822
Pubmed

The role of hepatic expression of STAT1, SOCS3 and PIAS1 in the response of chronic hepatitis C patients to therapy.

STAT1 SOCS3

9.16e-053193223472246
Pubmed

PIKE-mediated PI3-kinase activity is required for AMPA receptor surface expression.

AGAP2 GRIA2

9.16e-053193221847098
Pubmed

HtrA proteins as targets in therapy of cancer and other diseases.

HTRA2 HTRA3

9.16e-053193220469960
Pubmed

Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice.

OPA1 YME1L1

9.16e-053193226785494
Pubmed

Neural-specific deletion of Htra2 causes cerebellar neurodegeneration and defective processing of mitochondrial OPA1.

HTRA2 OPA1

9.16e-053193225531304
Pubmed

SOCS-3 is downregulated in progressive CKD patients and regulates proliferation in human renal proximal tubule cells in a STAT1/3 independent manner.

STAT1 SOCS3

9.16e-053193223108375
Pubmed

In vitro and in vivo evidence for an inflammatory role of the calcium channel TRPV4 in lung epithelium: Potential involvement in cystic fibrosis.

PLA2G4A TRPV4

9.16e-053193227496898
Pubmed

Changes in expression of human serine protease HtrA1, HtrA2 and HtrA3 genes in benign and malignant thyroid tumors.

HTRA2 HTRA3

9.16e-053193222923201
Pubmed

Expression of HTRA Genes and Its Association with Microsatellite Instability and Survival of Patients with Colorectal Cancer.

HTRA2 HTRA3

9.16e-053193232486357
Pubmed

Intragenic enhancers act as alternative promoters.

TG NPRL3

9.16e-053193222264824
Pubmed

Developmental origin dictates interneuron AMPA and NMDA receptor subunit composition and plasticity.

GRIA2 GRIN2B

9.16e-053193223852113
Pubmed

CIS3/SOCS-3 suppresses erythropoietin (EPO) signaling by binding the EPO receptor and JAK2.

EPOR SOCS3

9.16e-053193210882725
Pubmed

The caveolin scaffolding domain modifies 2-amino-3-hydroxy-5-methyl-4-isoxazole propionate receptor binding properties by inhibiting phospholipase A2 activity.

PLA2G4A GRIA2

9.16e-053193214561756
Pubmed

Changes in mRNA and protein levels of human HtrA1, HtrA2 and HtrA3 in ovarian cancer.

HTRA2 HTRA3

9.16e-053193218241672
Pubmed

Elevated GRIA1 mRNA expression in Layer II/III and V pyramidal cells of the DLPFC in schizophrenia.

GRIA2 GRIN2B

9.16e-053193217942280
Pubmed

STAT1, STAT6 and adenosine 3',5'-cyclic monophosphate (cAMP) signaling drive SOCS3 expression in inactive ulcerative colitis.

STAT1 SOCS3

9.16e-053193223154639
Pubmed

Kremen2 drives the progression of non-small cell lung cancer by preventing SOCS3-mediated degradation of EGFR.

KREMEN2 SOCS3

9.16e-053193237270563
Pubmed

A "double adaptor" method for improved shotgun library construction.

SPATA2L STX7 DHX29 BAIAP3 GNPAT RCAN1 PCDHB10 DICER1 VPS13D IPO9 SHANK2 CHRD

9.61e-05574193128619474
Pubmed

The microRNA-processing enzyme Dicer is essential for thyroid function.

DICER1 TG CDH16

1.08e-0417193322132122
Pubmed

Prenatal expression of D-aspartate oxidase causes early cerebral D-aspartate depletion and influences brain morphology and cognitive functions at adulthood.

DAO GRIA2 GRIN2B

1.08e-0417193332185508
Pubmed

FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.

AARS1 PRPF6 MFF STAT1 PNPLA6 SEC16A ACAD9 RALGAPB IPO9 YME1L1 TOP2A CEP170B

1.47e-046011931233658012
Pubmed

Global Interactome Mapping of Mitochondrial Intermembrane Space Proteases Identifies a Novel Function for HTRA2.

MFF SEC16A HECTD1 CLUH NDUFAF5 HTRA2 ACAD9 YTHDC2 DICER1 OPA1 YME1L1

1.56e-045151931131617661
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

PABIR1 AARS1 VSIG10L SEC16A OXSM HECTD1 NELFE NDUFAF5 HTRA2 ACAD9 RALGAPB SEC31A DICER1 PKMYT1 CNNM3 IPO9 SMARCC1 CCDC120 SELENOI

1.62e-0413271931932694731
Pubmed

Molecular characterization and comparison of the components and multiprotein complexes in the postsynaptic proteome.

GRIA2 GRIN2B AGRN

1.79e-0420193316635246
Pubmed

The ULK1-FBXW5-SEC23B nexus controls autophagy.

SEC16A FBXW9 SEC31A

1.79e-0420193330596474
Pubmed

Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels.

RELN JAG2 SLIT1

1.79e-0420193329961574
Pubmed

WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.

PRPF6 STAT1 RRP12 PWP2 DHX29 NELFE U2SURP YTHDC2 CTDP1 SMARCC1 SRRM2 TOP2A

1.82e-046151931231048545
Pubmed

The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission.

OPA1 YME1L1

1.82e-044193224616225
Pubmed

Suppressor of cytokine signalling (SOCS) proteins as guardians of inflammatory responses critical for regulating insulin sensitivity.

SOCS6 SOCS3

1.82e-044193224966052
Pubmed

Ciliary neurotrophic factor protects mice against streptozotocin-induced type 1 diabetes through SOCS3: the role of STAT1/STAT3 ratio in β-cell death.

STAT1 SOCS3

1.82e-044193223038263
Pubmed

Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteins.

SHROOM2 SHROOM1

1.82e-044193216684770
Pubmed

Genetics of peroxisomal enzymes in the mouse: nonlinkage of D-amino acid oxidase locus (Dao) to catalase (Cs) and L-alpha-hydroxyacid oxidase (Hao-1) loci on chromosome 2.

DAO HAS1

1.82e-044193213782
Pubmed

Cutting edge: Suppressor of cytokine signaling 3 inhibits activation of NFATp.

RCAN1 SOCS3

1.82e-044193211970967
Cytoband5q31

PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

1.32e-0411519355q31
GeneFamilyClustered protocadherins

PCDHGC5 PCDHB10 PCDHB9 PCDHB6 PCDHB2

5.62e-0564116520
GeneFamilyPDZ domain containing

MAST4 PPP1R9B HTRA2 HTRA3 SHROOM2 SHANK2

4.44e-0415211661220
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

PPP1R12B PPP1R9B PKMYT1 AATK ELFN1 AKAP11

1.11e-031811166694
GeneFamilySH2 domain containing|Suppressors of cytokine signaling

SOCS6 SOCS3

1.11e-0381162764
GeneFamilyFibulins

HMCN2 FBLN7

1.11e-0381162556
ToppCellTracheal-10x5prime-Stromal-Schwann|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RELN GLDN APC2 NRXN3 GRIA2 KCNK12 GRIN2B AATK SORCS3

1.83e-071961919b6226163d9fc93ecfff2115bb74408303a000490
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6|TCGA-Stomach / Sample_Type by Project: Shred V9

RRP12 NECTIN2 SEC16A PLA2G4A ELF4 SRRM2 TOP2A CEP170B

4.47e-071591918655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

PPP1R12B DBNDD2 HMCN2 HIPK4 SMTN TCF23 SORCS3

1.10e-06124191757f3335f751868a768934c757b06a6378148dc9e
ToppCelldroplet-Lung-nan-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN NRXN3 NECTIN2 RIPOR1 DOCK6 PCDHB9 SMTN CCDC120

1.58e-061881918a6ed43fdd42d681c9fbb2fb368947ab7e41d8d7c
ToppCelldroplet-Lung-nan-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN NRXN3 NECTIN2 RIPOR1 DOCK6 PCDHB9 SMTN CCDC120

1.58e-06188191854550313db78b3b5b572fa1e67092c8f6f33aab5
ToppCellfacs-Trachea-3m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CAPN9 BCL11A CCKAR TCF23 SORCS3 FYB1 MCTP2

2.99e-0614419178bd042f12186f36bc5aabf6a0232270a448f4b58
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

THSD4 NEURL2 TRPM2 FCGBP FOXD4L1 TG FYB1

8.93e-0617019174232fe937909f93d3736988c707b8f95ce993398
ToppCellE18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN STK11IP FCGBP RIPOR1 KHNYN KLHDC9 DCHS1

1.16e-051771917767b2af5f224d100b22bed32f86cec1cd17e8711
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN GLDN KCNH8 KCNQ5 SHROOM2 SHROOM1 AATK

1.16e-05177191759cf56c385c324f0844f20003d2b5049a2791e45
ToppCellE18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN STK11IP FCGBP RIPOR1 KHNYN KLHDC9 DCHS1

1.16e-0517719175ef2527e9b41e62f1724cdabaad9d8979266bb7d
ToppCellE18.5-Endothelial-Endothelial_lymphatic|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN STK11IP FCGBP RIPOR1 KHNYN KLHDC9 DCHS1

1.16e-051771917ae1d2fdd4f67f50c906b27ea084de058c6908aa2
ToppCellE18.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RELN STK11IP FCGBP RIPOR1 KHNYN KLHDC9 DCHS1

1.16e-0517719178dfadd9852e0c256363471a7cfe6af120c8c51e0
ToppCellILEUM-inflamed-(9)_Neuro_cell|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RELN GLDN NRXN3 RCAN1 PCDHB2 DCHS1 SERPINA5

1.20e-051781917611504b0a9e6318b18fba83787b03f9245c82252
ToppCellILEUM-inflamed-(9)_Enteric_neurons|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RELN GLDN NRXN3 RCAN1 PCDHB2 DCHS1 SERPINA5

1.20e-051781917d9142151819afb0dc22bfb32a9c9dba5f553067d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN EXPH5 NRXN3 CA9 UNCX KCNK12 BARHL2

1.29e-0518019176ac62bf1251978c8c12e715f7b73144fca619794
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CHD3 STAT1 MAST4 SOCS3 NSMCE3 FYB1 FCMR

1.39e-0518219171aea96ee211f7b9caef7fd385233f51be6021a73
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL11A NRXN3 SLC29A4 OXR1 ARX GRIA2 MCTP2

1.39e-051821917eb4be1c02b8b033d025e57b8b4cdbfaec4698054
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CHD3 STAT1 MAST4 SOCS3 NSMCE3 FYB1 FCMR

1.39e-051821917b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHD3 STAT1 MAST4 SOCS3 NSMCE3 FYB1 FCMR

1.39e-051821917c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CHD3 STAT1 MAST4 SOCS3 NSMCE3 FYB1 FCMR

1.39e-0518219174cb182ef39be2044a6ad7266f332d4177591e550
ToppCellCOVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated|COVID-19_Mild / Disease group, lineage and cell class

CHD3 STAT1 MAST4 SOCS3 NSMCE3 FYB1 FCMR

1.44e-0518319177717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCelldroplet-Lung-nan-21m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR FCGBP NOXO1 NECTIN2 SHROOM2 CCDC120 IRX2

1.49e-0518419177cc3b9bba1f600b40b02fe2456b5d007dbf9fa37
ToppCelldroplet-Lung-nan-21m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR FCGBP NOXO1 NECTIN2 SHROOM2 CCDC120 IRX2

1.49e-05184191753b71c4ac86dc5e42763b8f64fbc917177531017
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN EXPH5 NRXN3 CAMTA1 UNCX KCNK12 BARHL2

1.60e-051861917d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN EXPH5 NRXN3 UNCX BARHL2 IRX2 DNAH11

1.66e-0518719171b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 NCDN NRXN3 PIP5KL1 AGAP2 HIPK4 GRIN2B

1.66e-051871917e04a84989d624378141042768383b9c846901f2d
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 NCDN NRXN3 PIP5KL1 AGAP2 HIPK4 GRIN2B

1.66e-05187191724cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 NCDN NRXN3 PIP5KL1 AGAP2 HIPK4 GRIN2B

1.66e-0518719172f153b203fe79f206319603cf94d3a03ab49a05d
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Interneuron|GW10 / Sample Type, Dataset, Time_group, and Cell type.

EPOR P4HA3 NRXN3 ARX YTHDC2 SCUBE3

1.75e-051261916ec445ec097c9c45cd47b8cfa8c140df5b298695e
ToppCellcellseq2-Endothelial-Endothelial_Vascular-Endothelial_large_blood_vessel-VEC|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MAP3K12 JAG2 RIPOR1 BRAT1 MIER2 LRRK1 DCHS1

1.77e-051891917bccb3481ffed597c845fe860da658505316105b5
ToppCellHippocampus-Neuronal-Excitatory|Hippocampus / BrainAtlas - Mouse McCarroll V32

NCDN SPATA2L AGAP2 GRIA2 KCNK12 SLIT1 CHRD

1.77e-0518919174b90d181eb0a42814eeb23bc82e52fd3a12392a7
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN NRXN3 NECTIN2 DOCK6 PCDHB9 SMTN CCDC120

1.83e-051901917e80d66ba0d5c263e94c1ab0b89d1dc7b837af3e1
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN NRXN3 NECTIN2 DOCK6 PCDHB9 SMTN CCDC120

1.83e-051901917f32d66c0e74e0a2a23ecb857c4daf0d8573a806c
ToppCelldroplet-Lung-18m-Endothelial-lymphatic_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN NRXN3 NECTIN2 DOCK6 PCDHB9 SMTN CCDC120

1.83e-051901917b79ffd05806244a9790cd04c66fb4f92c824e69f
ToppCellVE-CD4-CD4_Treg|VE / Condition, Cell_class and T cell subcluster

APC2 SLC29A4 OSGIN1 FBLN7 NDUFAF5 HELZ2

2.00e-051291916e89d414e1b23e1656747defa39f09b51944a2166
ToppCellPCW_07-8.5-Epithelial-Epithelial_neuroendo|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

KCNH8 BAIAP3 ERICH3 ARX SHANK2 IRX2 MCTP2

2.10e-051941917b30379f8dc41c86c746af9930541fbb4819d8fa0
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC16A BAIAP3 SEC31A DPP3 SRRM2 CEP170B SON

2.10e-0519419170b023de48ed8a550d169bbe954881eb04bf4f981
ToppCellTracheal-10x5prime-Stromal-Schwann-Schwann_nonmyelinating|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

RELN APC2 NRXN3 GRIA2 GRIN2B AATK SORCS3

2.31e-051971917e239caae24f40564a24ad909754f5436f767ccdb
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

CHD3 STAT1 SLC29A4 NPR2 HELZ2 SCUBE3 AKAP11

2.39e-051981917ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRXN3 KCNQ5 GLRB OXR1 GRIA2 GRIN2B SHANK2

2.39e-0519819174ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellFrontal_cortex-Neuronal|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

NCDN NRXN3 CAMTA1 GRIA2 GRIN2B AKAP11 CEP170B

2.47e-051991917f88039d862f3bfa01dc39d2de4f3f548dc5a0e61
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLDN SOCS6 FCGBP GAL3ST4 PKMYT1 CD33 TOP2A

2.55e-052001917a1503bcc774bed9563eda7cf90b8b5bf4405ad85
ToppCell10x_5'_v1-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLDN SOCS6 FCGBP GAL3ST4 PKMYT1 CD33 TOP2A

2.55e-05200191725247f8b6ba6cd899ba6bd47e28e090d697e4632
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLA2G4A BAIAP3 IRS4 ARX SHROOM2 HYI

4.84e-051511916090b067873740c282865e2d02cf47d5cb3dd7607
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD3 NCDN AGAP2 HIPK4 GRIN2B FYB1

5.59e-05155191672a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

GLDN DCBLD1 HMCN2 BAIAP3 PLLP SELENOI

5.80e-051561916fc8b8aef29d6d1c0f0c1d08280d8aaff8d30535e
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN PNPLA6 GLRB GRIA2 TCF23 CHRD

6.44e-0515919164000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN PNPLA6 GLRB GRIA2 TCF23 CHRD

6.44e-0515919167619d0d49738dd08daf01b42664691a5323aa793
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TRPM2 DAO NPR2 SOCS3 SCARF1 AATK

6.91e-05161191678cc5bc488bc47726195a649946d414e6bfabf94
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN BAIAP3 ARX PLLP ELFN1 DCHS1

6.91e-051611916dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DOCK6 SLC29A4 ERICH3 NUDT17 SLIT1

7.11e-051001915cb0deaf1c33d2789417e93cc01d94e34a611d20a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN KCNH8 NRXN3 GRIN2B AATK SORCS3

7.15e-051621916eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCellBrain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Cajal-Retzius|3_mon / Sample Type, Dataset, Time_group, and Cell type.

RELN DMRT3 MAST4 KLHDC9 ELFN1 BARHL2

7.15e-0516219161f589a763f3fd4e1e612809ef3903879d47dc1d8
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_5|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRPM2 DAO NPR2 SOCS3 SCARF1 AATK

7.15e-0516219160fa93efc9c005d1e649b3f7069ae8641d6e41ed8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN KCNH8 NRXN3 GRIN2B AATK SORCS3

7.15e-051621916e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN KCNH8 NRXN3 GRIN2B AATK SORCS3

7.15e-051621916d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RELN KCNH8 NRXN3 GRIN2B AATK SORCS3

7.15e-0516219165bbd7130d4dad9035e73a439dda568195c136f31
ToppCellfacs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TG SHANK2 ELFN1 CCDC120 TRPV4 CDH16

7.65e-051641916cdb8cd2d6b369189ea77e4946738e2816d502e03
ToppCellfacs-Trachea-18m-Epithelial-glandular_epithelial-lung_secretory_cell-mucous|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TG SHANK2 ELFN1 CCDC120 TRPV4 CDH16

7.65e-051641916f1423f4434af4af9c60c8a5b0b0abec4a7df9401
ToppCellfacs-Trachea-18m-Epithelial-glandular_epithelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TG SHANK2 ELFN1 CCDC120 TRPV4 CDH16

7.65e-0516419165dbfcdd450f652b16d97da53b528d4584b0eabcf
ToppCell5'-GW_trimst-2-LargeIntestine-Epithelial-neuro-epithelial-EECs|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCNH8 NOXO1 BAIAP3 SLC29A4 ERICH3 ARX

7.91e-0516519164b4e75ad0eb0a6b00c30a000ec6267e23ba2e496
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CHD3 STAT1 FOXD4L1 GRIA2 VPS13D ZBED1

8.18e-0516619169fd9de82f98b9acdaa59ac98fb9664161514aec0
ToppCell356C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

NEURL2 DCBLD1 YTHDC2 NSMCE3 TG AATK

8.45e-0516719167e61c5d2cdcfa6a2e3484b3994aec6b64ad75f07
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|390C / Donor, Lineage, Cell class and subclass (all cells)

NEURL2 FCGBP GAL3ST4 CD33 SLIT1 TRPV4

9.02e-0516919162c851b2703c7b8b656026f996f5fc027e4a79b36
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-6_VIP_PENK|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RELN HMCN2 NECTIN2 FAT4 ELFN1 DNAH11

9.02e-051691916eb3b8e473192c4b8688f2f8da400116dd6fe193d
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NEURL2 NRXN3 CLUH CA9 TG HYI

9.02e-051691916813472d429c0b12580b17b440e00a6d8beb7947f
ToppCelldroplet-Heart-4Chambers-18m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOXO1 TG PKMYT1 PROX2

9.73e-0556191464bb7d3632b14452b6b861f73880b1dab729a0cf
ToppCellCOVID-19_Mild-Neu_2|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

THSD4 TRPM2 PTPN9 ACSF3 OXR1 HTRA3

9.94e-051721916f5fd08b42c002d4693646b27e7b708eceb49524f
ToppCell356C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

NEURL2 DCBLD1 HTRA2 YTHDC2 TG AATK

9.94e-0517219169dca1542145d88559527db7e0f6ad150df59ca2d
ToppCellCOVID-19-Heart-Neuronal|Heart / Disease (COVID-19 only), tissue and cell type

RELN GLDN KCNH8 NRXN3 IRS4 SORCS3

1.03e-0417319166fb5f9e6536a5d57fd8e6657b494047a2d0bc9c7
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BCL11A AGAP2 CA9 FBRSL1 TG TOP2A

1.03e-0417319166c9ecf77d2fb0f89100fdd7e4e88f85598278bc7
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB|TCGA-Thymus / Sample_Type by Project: Shred V9

EPHB3 THSD4 HS6ST2 P4HA3 KCNQ5 IRX2

1.09e-04175191650f9b994bdd389158f92f891944ea81b2fb15eef
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-tracheal_fibroblast|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NEURL2 FBLN7 NUDT17 ELFN1 SORCS3 AKAP11

1.09e-041751916085cceb1fc2c4ae2f27e85cea5702defecc2cf44
ToppCelldroplet-Fat-Mat-18m-Hematologic-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DCBLD1 CHD3 KCNQ5 RFFL SELENOI TOP2A

1.13e-041761916867936a20f73f638055c19c8d88834aa2cc657cf
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

EPHB3 AARS1 FCGBP FAM83F PPP1R9B SMTN

1.16e-041771916e1e45956887371b1c18f1eb479dd930031497520
ToppCellPCW_13-14-Neuronal-Neuronal_SCP|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RELN KCNH8 NRXN3 GLRB GRIN2B AATK

1.16e-041771916621dd82f1393c961d4dd7a615aa52c9df9e36336
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

SPEG KCNQ5 FAT4 PCDHB6 PCDHB2 SMTN

1.16e-041771916b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 UNCX ARX GRIA2 IRX2 DNAH11

1.16e-0417719161dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CAPN9 EXPH5 ELFN1 SCUBE3 SERPINA5 CDH16

1.16e-041771916c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RELN BAIAP3 IRS4 ARX ELFN1

1.27e-041131915feb3c6a7723263d58e5ce020a0097fedfcf78ca8
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KREMEN2 LACTBL1 BAIAP3 TICRR IRS4 PKMYT1

1.27e-0418019168cef63866c205df3825df84ce51fa61aa04ae491
ToppCell3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAST4 RCAN1 SOCS3 PCDHB2 ELFN1 DCHS1

1.44e-04184191616ed515fb673a9d6973133afcda0a3fba4a8d9dc
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAG2 DOCK6 FAT4 HIPK4 TCF23 DCHS1

1.48e-041851916f98af3146ec2f44c30d31a662fb9c4fa3ca4f706
ToppCell343B-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EPOR SOCS6 BCL9 PLA2G4A MIER2 YTHDC2

1.48e-0418519161b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

JAG2 MAST4 HTRA3 PLLP SHROOM1 AATK

1.48e-041851916b57dae20c21f984edd2acee4344d86f033108ebf
ToppCell343B-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EPOR SOCS6 BCL9 PLA2G4A MIER2 YTHDC2

1.48e-04185191602cbf492bc40abebaa93a3a208888afae72fbe06
ToppCelldroplet-Skin|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KREMEN2 TMOD4 FCGBP FAM83F GAL3ST4 IRX2

1.48e-041851916657fd191ed160f8620d57b33820ec7222806f289
ToppCell367C-Endothelial_cells-Endothelial-B_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

JAG2 MAST4 HTRA3 PLLP SHROOM1 AATK

1.48e-041851916d3b054d203e575c1bb5455aa7a2e551a0957a760
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

AGAP2 ARX GRIN2B ELFN1 SCUBE3 MCTP2

1.52e-041861916bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

KCNH8 EXPH5 HS6ST2 FCGBP SHANK2 IRX2

1.52e-041861916bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

KCNH8 EXPH5 HS6ST2 SHANK2 IRX2 CDH16

1.57e-041871916db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

RRP12 SEC16A ACAD9 NUDT17 SMTN TOP2A

1.57e-0418719163c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

KCNH8 HS6ST2 BCL11A MAST4 SHANK2 TRPV4

1.57e-0418719168407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Striatum / BrainAtlas - Mouse McCarroll V32

HS6ST2 NCDN AGAP2 GRIA2 GRIN2B HAS1

1.61e-041881916e34ea7014c5a059a7db38f78bd903cf02616ddd3
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HS6ST2 FBLN7 UNCX SORCS3 CCDC120 IRX2

1.61e-041881916c300accbac71a3bc075fe985543d8a8ead82531b
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

HECTD1 FBLN7 SOCS3 NSMCE3 FYB1 YME1L1

1.61e-041881916939790f133eac9c12d08db6ddb5f08f5107844e3
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RELN GLDN NEURL2 NSMCE3 PLLP EHHADH

1.61e-041881916c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCellCTRL-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

BCL11A RIPOR1 STX7 LRRK1 AKAP11 FCMR

1.66e-04189191614f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCellControl-Myeloid-MoAM1|Control / Disease group,lineage and cell class （2021.01.30）

TRPM2 NECTIN2 FNIP2 SOCS3 GAL3ST4 FYB1

1.66e-04189191655d5c2fb9e6ab556d42c83a1e985ee66e4cf9dba
ToppCellBAL-Control-Myeloid-MoAM-MoAM1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TRPM2 NECTIN2 FNIP2 SOCS3 GAL3ST4 FYB1

1.66e-041891916ebb5e069fdca7cf8ffac16a57572e92d2593c86a
DrugAmyleine hydrochloride [532-59-2]; Up 200; 14.8uM; PC3; HT_HG-U133A

CAPN9 NRXN3 RRP12 AGAP2 OSGIN1 CA9 KCNK12 LRRK1 HAS1 CDH16

5.89e-06196189104089_UP
DrugTriflusal [322-79-2]; Up 200; 16.2uM; MCF7; HT_HG-U133A

CAPN9 EPOR EXPH5 MAST4 RIPOR1 RCAN1 SOCS3 YTHDC2 IPO9 CTDP1

6.44e-06198189107451_UP
Drugalpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A

EPOR SOCS6 MAP3K12 PNPLA6 MAST4 CA9 IRS4 ST7 CTDP1 FCMR

7.04e-06200189106970_UP
DiseaseVan Maldergem Wetzburger Verloes syndrome

FAT4 DCHS1

3.58e-0521772C1832390
DiseaseVan Maldergem syndrome

FAT4 DCHS1

3.58e-0521772cv:C1832390
DiseasePeriventricular gray matter heterotopia

FAT4 DCHS1

3.58e-0521772C1849173
DiseaseIntellectual Disability

APC2 ASH1L PEX6 CHD3 BCL11A KCNQ5 OXR1 PTPN23 GRIA2 GRIN2B SHANK2

8.76e-0544717711C3714756
DiseaseSchizophrenia

RELN DAO BCL11A BCL9 JAG2 NRXN3 PLA2G4A PPP1R9B GNPAT GRIA2 GRIN2B DICER1 OPA1 CCKAR PLLP MCTP2

9.00e-0588317716C0036341
Diseaseopioid dependence

EPHB3 DAO NRXN3 RIPOR1 FAT4 GRIN2B CTDP1 FYB1

9.78e-052371778EFO_0005611
DiseaseApraxia of Phonation

CHD3 BCL11A

1.07e-0431772C0264611
DiseaseHeterotopia, Periventricular, Autosomal Recessive

FAT4 DCHS1

1.07e-0431772C1842563
Diseaseschizophrenia (is_marker_for)

RELN PPP1R9B OPA1 PLLP

1.41e-04441774DOID:5419 (is_marker_for)
DiseaseMalignant neoplasm of salivary gland

BCL11A MIER2 TOP2A SON

1.54e-04451774C0220636
DiseaseSalivary Gland Neoplasms

BCL11A MIER2 TOP2A SON

1.83e-04471774C0036095
DiseaseMalformation of cortical development

RELN ARX

5.28e-0461772cv:C1955869
DiseaseLissencephaly

RELN ARX

5.28e-0461772cv:C0266463
DiseaseBipolar Disorder

RELN TRPM2 DAO BCL9 PLA2G4A GRIA2 GRIN2B CCKAR SHANK2 EHHADH

6.47e-0447717710C0005586
Diseasehemoglobin subunit zeta measurement

BCL11A NPRL3

7.37e-0471772EFO_0801670
DiseaseMalignant neoplasm of breast

EPOR PPP1R12B APC2 BCL11A STAT1 JAG2 FAM83F NECTIN2 PLA2G4A OXSM AGAP2 B3GALNT2 SIK3 NUDT17 SHROOM2 TOP2A

7.85e-04107417716C0006142
Diseasesickle cell anemia

BCL11A NPRL3

9.78e-0481772MONDO_0011382
Diseasecerebellar ataxia (implicated_via_orthology)

AARS1 PNPLA6

9.78e-0481772DOID:0050753 (implicated_via_orthology)
Diseasecortical surface area measurement

THSD4 RELN PPP1R12B STAT1 JAG2 TBC1D16 DMRT3 MAST4 PPP1R9B FNIP2 TICRR NPR2 KHNYN GAL3ST4 TG PKMYT1 MCTP2 DNAH11

1.26e-03134517718EFO_0010736
DiseaseCognitive impairment

NECTIN2 NAALADL2

1.90e-03111772HP_0100543
DiseaseBipolar I disorder

DAO NRXN3

1.90e-03111772C0853193
Diseaseobesity (implicated_via_orthology)

CAPN9 STAT1 SEC16A FAT4 CCKAR DCHS1

1.95e-032151776DOID:9970 (implicated_via_orthology)
Diseaseovarian reserve

GRIN2B NPRL3

2.27e-03121772EFO_0004770
Diseasecolorectal cancer (is_marker_for)

IRS4 HTRA2 DICER1 BARHL2 SMARCC1

2.63e-031571775DOID:9256 (is_marker_for)
Diseasesterol measurement

NECTIN2 SIK3

2.67e-03131772EFO_0010231
Diseasecerebrospinal fluid biomarker measurement

NRXN3 TUT1 SIK3 CD33

2.71e-03961774EFO_0006794
Diseaseage at last pregnancy measurement

BARHL2 SORCS3

3.11e-03141772EFO_0009440
DiseaseAdenoid Cystic Carcinoma

BCL11A MIER2 TOP2A SON

3.14e-031001774C0010606
Diseasestatus epilepticus (biomarker_via_orthology)

RELN HTRA2 SOCS3 GRIA2

3.14e-031001774DOID:1824 (biomarker_via_orthology)
Diseasebirth weight, pelvic organ prolapse

LINC02906 NAALADL2 SLIT1

3.19e-03491773EFO_0004344, EFO_0004710
Diseasemyeloid cell surface antigen CD33 measurement

VSIG10L CD33

3.57e-03151772EFO_0008238
DiseaseSchizoaffective disorder-bipolar type

NRXN3 PKMYT1

4.06e-03161772EFO_0009965
DiseaseBlood Platelet Disorders

PLA2G4A FYB1

4.06e-03161772C0005818
Diseasecentral nervous system disease (implicated_via_orthology)

GRIA2 SEC31A

4.06e-03161772DOID:331 (implicated_via_orthology)
DiseaseHuntington Disease

RELN RCAN1

4.59e-03171772C0020179
DiseaseCharcot-Marie-Tooth disease type 2

AARS1 TRPV4

4.59e-03171772cv:C0270914
DiseaseAlzheimer's disease (is_marker_for)

EPOR RELN PPP1R9B HTRA2 GRIN2B OPA1

4.69e-032571776DOID:10652 (is_marker_for)
DiseaseUnipolar Depression

RELN BCL9 GRIA2 CCKAR TG MCTP2

4.86e-032591776C0041696
DiseaseAutistic Disorder

RELN DAO NRXN3 PLA2G4A GRIN2B SHANK2

5.05e-032611776C0004352
Diseaseconcentration of chylomicrons and extremely large VLDL particles measurement

NECTIN2 SIK3 AGRN

5.39e-03591773EFO_0022260
DiseaseDiGeorge syndrome (implicated_via_orthology)

DICER1 CHRD

5.72e-03191772DOID:11198 (implicated_via_orthology)
Diseaseproliferative diabetic retinopathy

NRXN3 KCNQ5 NAALADL2

5.92e-03611773EFO_0009322
Diseaseage at first birth measurement

HS6ST2 FNIP2 SMARCC1 SORCS3

5.99e-031201774EFO_0009101

Protein segments in the cluster

PeptideGeneStartEntry
ERTLGAPASSERSAA

CTDP1

896

Q9Y5B0
ETRLSPFTGEAEASR

ERICH3

991

Q5RHP9
AAAVDSADRSPRPTS

EPB41

546

P11171
REAARDARAQSPSSG

FBRSL1

21

Q9HCM7
LREARGSPNTASAEA

BRAT1

736

Q6PJG6
SRSPRLVASGDDSVD

ASH1L

1701

Q9NR48
TLSPSEGVRDFSREL

CAMTA1

1286

Q9Y6Y1
SSSGSVRSPRAFRAE

ELFN1

641

P0C7U0
VRRGEFSSSDPNIRA

CXorf49;

421

A8MYA2
SNSERLSGSAEPRSF

CTAGE6

631

Q86UF2
SNSERLSGSAEPRSF

CTAGE15

631

A4D2H0
FRRRTEQDPGSASAD

BAIAP3

56

O94812
SFRIDPESGDLIATR

FAT4

1786

Q6V0I7
TEPASGSDAASIRSR

ACAD9

181

Q9H845
AAGATARATTASRLP

AGRN

1266

O00468
RDFREAPTLRLTSGA

DNAH11

11

Q96DT5
REDSGLFSPIRSSAF

AKAP11

441

Q9UKA4
RSSAASVGRADAPVA

AGAP2

1176

Q99490
RSFLAELSRAPRGAS

GLDN

66

Q6ZMI3
DRSAPVFTRALAFGD

ACSF3

41

Q4G176
DVFGESLRAGPTRAT

NPR2

256

P20594
ASAERRLSGTPISFI

CCKAR

341

P32238
SRASSATFRPVIRGD

CEP170B

601

Q9Y4F5
SDAGVGVRSLPADFR

DICER1

1076

Q9UPY3
ATAAAAAAGSREPRV

DHX29

46

Q7Z478
STAFARVDEALGRPG

CA9

256

Q16790
RRDLSSADPAVLGAT

ZFYVE19

61

Q96K21
AAEAAEARARPGVTL

RCAN1

16

P53805
ASVSALRPDLGFVRS

PLLP

21

Q9Y342
RRGAAAADLLSSSPE

PTPN23

1111

Q9H3S7
VRDPTGASIALFTAR

PTPN9

101

P43378
PERAAARGDTFSALT

P4HA3

21

Q7Z4N8
ADRFTPLTTTDVAAG

DAO

36

P14920
FRVGAADRGSPALSS

PCDHB2

531

Q9Y5E7
ADRGSPALSSEALVR

PCDHB2

536

Q9Y5E7
GTADTAPLERISAAR

LINC02906

66

E5RJ46
AGFSRARALSTNSDP

OXSM

246

Q9NWU1
EGSVAGDSAFSRAPR

FBLN7

181

Q53RD9
TRTLDRDQGPSSFDF

DCHS1

641

Q96JQ0
NESRRADVLAFPSSG

PNPLA6

1276

Q8IY17
RAASRVSAVSEPGLL

FBXW9

66

Q5XUX1
EDERGPGSSLIFRTA

PIP5KL1

291

Q5T9C9
SPAERRRVSSNGIFD

MCTP2

126

Q6DN12
DASSRATGIPDRFSG

IGKV3D-20

71

A0A0C4DH25
FLTARGDPDDAARRS

NCDN

136

Q9UBB6
FVSSSDRLRELGPDG

NELFE

136

P18615
SSDTSLGRVSRAAFP

MFF

6

Q9GZY8
SRRPESVSFARSVCG

NUDT17

11

P0C025
GGSVASRLTFPDREA

HIPK4

296

Q8NE63
RSGTEAASVLEFPAF

LRRK1

531

Q38SD2
IAAFIRTSGTTAAPR

ELF4

521

Q99607
SRSRQPDSGVLFFES

HMCN2

836

Q8NDA2
ASAVEVAVSFSPARD

JAG2

1021

Q9Y219
FREGAIISRDSPVAT

CD33

61

P20138
QPAREAAFASDSLRT

KCNQ5

891

Q9NR82
SVSREASGLAEGRFP

BCL11A

246

Q9H165
ADPASDRASLFVART

CCDC120

341

Q96HB5
ADIRGFSAPRTFGLT

EHHADH

61

Q08426
RSAEPSVFVRTTAEG

GRIA2

696

P42262
PATFRRGSALSEADS

KCNK12

191

Q9HB15
RISESAASGARFPLD

PCDHGC5

141

Q9Y5F6
FFDELDSLAPSRGRS

PEX6

801

Q13608
DDVPFTARVGGRSLS

NPRL3

426

Q12980
RFGTPASLTTRDPEA

FYB1

91

O15117
RRTPFTASGESEILD

NRXN3

561

Q9Y4C0
ASAAGLIRSFSERFP

DPP3

691

Q9NY33
APDESFSRLDAGRVN

EPHB3

161

P54753
RPAEFETTSERGSGA

EPHB3

536

P54753
AASRRSVFALSNEDP

EXPH5

1196

Q8NEV8
SESDLARGRLAPATD

KREMEN2

176

Q8NCW0
RSNDFSIVGSLPRDF

GLRB

416

P48167
DTSPVFQAEAPSARR

PABIR1

46

Q96E09
TAEGTAFRLERAQDP

PCDHB10

146

Q9UN67
SIVRDPAALARSAFS

GAL3ST4

156

Q96RP7
VDPSGTRATRVESFA

NEURL2

36

Q9BR09
PRSEELARSASGSAF

IRX2

31

Q9BZI1
DEDLAATRTQRPSGF

IRGC

171

Q6NXR0
FPAVSALVSRTADAD

MFSD14A

351

Q96MC6
ADPVRLEFSRDFGAT

RELN

2036

P78509
EFFRAVSAGRDSDPS

PROX2

551

Q3B8N5
GSPEETAFRATDRGS

OPA1

186

O60313
IRDAGNDSASTAPRS

OXR1

316

Q8N573
RLPSELDAGSVRFTV

APC2

1251

O95996
ASLADRFTRRGVDPA

HECTD1

211

Q9ULT8
PARVRAAGSSGFEAV

HYI

21

Q5T013
TAGISFAIPSDRLRE

HTRA2

326

O43464
AGISFAIPSDRITRF

HTRA3

326

P83110
TGFDLTPDVRARLAA

LACTBL1

216

A8MY62
DTPRSSGASSIFDLR

DOCK6

181

Q96HP0
APVEFFLEGTRSRSA

GNPAT

236

O15228
AETNRSVFPLGSEAR

LINC00322

211

Q6ZN03
EVPVAALAGAASDRR

DBNDD2

11

Q9BQY9
GSAFRVPDTLRFSAD

DMRT3

331

Q9NQL9
SLAFDGDSFVRLRVP

FCGBP

2186

Q9Y6R7
SETFADGVPREGLSR

CHD3

1471

Q12873
FRTEGDIPRNESSDS

FNIP2

881

Q9P278
SSGLPEDRVVSVSFR

B3GALNT2

136

Q8NCR0
RSISADSFDQRDPGT

BCL9

101

O00512
FLEGLRTSPEDARTS

CPTP

121

Q5TA50
VGATVAPSSRRDFTF

SERPINA5

36

P05154
GEARTADFRSQATPS

BARHL2

36

Q9NY43
RGPLDAATARSVALT

HAS1

86

Q92839
AAGSPESRASRVRAD

MAP3K12

61

Q12852
PETRAGVREASAASS

MAST4

2466

O15021
ALADPATAAADRRAS

ARX

516

Q96QS3
TASALGTESPRFLDR

FIMP

51

Q96LL3
GTEFRAPPRSAAASE

FOXD4L1

86

Q9NU39
LDPRTSEFTAAFVGR

IPO9

751

Q96P70
ARRTNSSTPLGELFD

SELENOI

111

Q9C0D9
SFVPLELRVTAASGA

EPOR

116

P19235
AREPSSDTVVFDPAR

KLHDC9

51

Q8NEP7
ARPASPDRFAVSAEA

KHNYN

6

O15037
AELAASRPGSVAASV

HS6ST2

36

Q96MM7
QLTDFSPSRATDGRV

C19orf54

311

Q5BKX5
SRSLSFEPDGQIRAS

DCBLD1

256

Q8N8Z6
ARGERFRVPSSTADF

HELZ2

221

Q9BYK8
TRSAAESEARTPFGL

CAPN9

236

O14815
SRARFLPESENGFTV

SCUBE3

431

Q8IX30
SDRDEPGTANSDLRF

CDH16

151

O75309
RFLADEDREPGSSAS

MIER2

166

Q8N344
ELARVPRSAFSAGLS

OTOL1

336

A6NHN0
ALEAATRVGAVTPAS

OSGIN1

271

Q9UJX0
EFRVGATDRGSPALS

PCDHB6

526

Q9Y5E3
TAEGTAFRLERAQDP

PCDHB9

146

Q9Y5E1
RGVDLIISFDFSARP

PLA2G4A

566

P47712
ARAAVSAFPTDSLER

IRS4

1096

O14654
SPRARDAATGFLLDG

STK11IP

306

Q8N1F8
ESSAAASPRRIRAEG

SPATA2L

326

Q8IUW3
VDGSSFDPQRRAREA

SRRM2

146

Q9UQ35
PGTFLLRFSESSREG

STAT1

596

P42224
FTDTSSDGLQARRPD

AATK

871

Q6ZMQ8
SIDSEDSFVPGRRAS

RFFL

226

Q8WZ73
DSFVPGRRASLSDLT

RFFL

231

Q8WZ73
CAETTRSGPFARSID

SORCS3

376

Q9UPU3
RSGPFARSIDISSLV

SORCS3

381

Q9UPU3
RVRASSRVSGSFPED

STX7

121

O15400
TGFTTRSDIGPARDA

PRPF6

26

O94906
TERFSPVRRFSDGAA

SIK3

616

Q9Y2K2
DAFRPASRSRSASGE

SHROOM1

296

Q2M3G4
VRRALARAASDSDPD

SHROOM1

726

Q2M3G4
AGTSDLPRRLGTFAE

SHROOM2

861

Q13796
VSDKFSPEAASRRGL

ST7

381

Q9NRC1
ARPAERGSATVSFGE

NDUFAF5

316

Q5TEU4
AERVARSPTITGFFA

NOXO1

111

Q8NFA2
FLASVVDPRVASAAA

SMARCC1

701

Q92922
EAARGEAAPARRFSS

FAM83F

426

Q8NEG4
SLARAKRPSVSFAEG

SCARF1

581

Q14162
FFSRPSGRSDLTVDA

RRP12

41

Q5JTH9
SPFAAAIAGAVRDRE

SHANK2

1076

Q9UPX8
RRNSPAFLSTDLGDE

SHANK2

1096

Q9UPX8
DAPSRRNRSSGVLDD

U2SURP

246

O15042
RPGFLSTAEEETLSR

ALKBH7

36

Q9BT30
DRPTRIRFSDSNGSV

CHRD

206

Q9H2X0
GGAARDTPDATFLLR

CNNM3

51

Q8NE01
AETIAADDGTDPRSR

CLUH

681

O75153
DSQGARSRPSRVSDF

TICRR

51

Q7Z2Z1
IPGSREFDVSFRSAE

ZCCHC3

206

Q9NUD5
PAAAFTAARSDAGIR

PIGX

26

Q8TBF5
GSLVAPDRLRFDFTA

AARS1

626

P49588
GPAAAASSLERETER

SEC16A

1606

O15027
RLELRDDGAFSTPTG

SPEG

146

Q15772
TDESEPATTPRGFRA

SARG

71

Q9BW04
RVSFRGEASETLQSP

PKMYT1

81

Q99640
ALTSDALAVTFRPDG

PWP2

541

Q15269
RSVFVSGFPRDVDSA

TUT1

56

Q9H6E5
RTLRASGFSSEADVP

TRPM2

1196

O94759
PISAALAESRGSVFL

TBC1D16

241

Q8TBP0
SRASSVAGDKPRTFL

FCMR

191

O60667
APDSIRGSFGLTDTR

NME6

111

O75414
RAARAPSATEGALTR

SCAND2P

206

Q9GZW5
SAEPAGTFLIRDSSD

SOCS3

61

O14543
NDRFSAERPEGSIST

TRBV7-6

81

A0A1B0GX31
VDAFLGISRPRSDSA

RALGAPB

346

Q86X10
VRSFSLVATRSGDPI

TMOD4

226

Q9NZQ9
ARVLRDGFAEEAPST

NSMCE3

36

Q96MG7
VRFRTTTGLDSAVDP

YME1L1

316

Q96TA2
PERVRSAAGATFDLS

TOMM22

56

Q9NS69
DFDSAVAPRAKSVRA

TOP2A

1501

P11388
RGESEFDSFRQSLPV

YTHDC2

181

Q9H6S0
APEAEALAAARERSS

TP53RK

16

Q96S44
RARGVPAFTDTTLDE

SLC29A4

46

Q7RTT9
ALGRSEASPENAARE

TCF23

71

Q7RTU1
VSSDRDAAPARFVTA

VSIG10L

406

Q86VR7
QPRFTDRETEAAAGT

nan

131

Q8N1Y9
VTATRVAPERLFGSA

ZBED1

611

O96006
RSRDETPALAGTDAS

THSD4

116

Q6ZMP0
PAVLSAASFDGRISV

SEC31A

316

O94979
ADFLRTNPIETSGAR

SLIT1

451

O75093
SPGSREARDSLAEAT

RIPOR1

171

Q6ZS17
QRRRFSPDDSAGASA

TG

1006

P01266
RPILFDIVSRGSTAD

TRPV4

151

Q9HBA0
VPDGSFLVRDSSDDR

SOCS6

401

O14544
IFDREDQASPRAGSL

SMTN

721

P53814
LLASDVGRDRSAASP

SON

1756

P18583
SDRFFAERPEGSVST

TRBV7-8

81

A0A1B0GX51
TRESRPGAVSFADVA

ZNF785

21

A8K8V0
DSAFARRSPDAVASP

UNCX

436

A6NJT0
LSFDIPTGSLRDSRA

VPS13D

1026

Q5THJ4
SQTFDFGSERIRSEP

KCNH8

826

Q96L42
GPSFLSEARFSTRAT

NAALADL2

601

Q58DX5
SPRVRFEDGAVFLAA

PPP1R12B

51

O60237
ETRKLFERSAPAAAG

PPP1R9B

146

Q96SB3
GSPQSALDFIRRESS

GRIN2B

916

Q13224
SRFTLVPSGRADGVT

NECTIN2

221

Q92692