Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

MISP CCDC8 AKAP9 CEP250 CGN NUMA1 DNAH2 CEP131 CEP152 PCNT

1.06e-057205210GO:0000226
GeneOntologyBiologicalProcessmicrotubule-based process

MISP CCDC8 AKAP9 CEP250 CGN NUMA1 DNAH2 CEP131 CEP152 KIF7 PCNT

5.34e-0510585211GO:0007017
GeneOntologyBiologicalProcesscentrosome localization

MISP AKAP9 SYNE1

9.34e-0535523GO:0051642
GeneOntologyBiologicalProcessmicrotubule organizing center localization

MISP AKAP9 SYNE1

1.02e-0436523GO:0061842
GeneOntologyBiologicalProcessorganelle assembly

MISP DCDC2 SYNE1 CEP250 NUMA1 DNAH2 ABCB6 CEP131 CEP152 WNK3 PCNT

1.03e-0411385211GO:0070925
GeneOntologyBiologicalProcesscalcium ion import

CACNB2 SLC24A2 ACE WNK3

1.09e-0498524GO:0070509
GeneOntologyBiologicalProcessprotein localization to microtubule organizing center

CEP250 NUMA1 CEP131

1.30e-0439523GO:1905508
GeneOntologyBiologicalProcessregulation of heart rate by cardiac conduction

CACNB2 AKAP9 ACE

1.51e-0441523GO:0086091
GeneOntologyBiologicalProcessregulation of protein localization to cell cortex

MISP NUMA1

2.22e-049522GO:1904776
GeneOntologyCellularComponentmicrotubule organizing center

MISP DCDC2 CCDC8 AKAP9 CEP95 CEP250 NUMA1 CCDC18 CEP131 CEP152 KIF7 PCNT

1.58e-069195112GO:0005815
GeneOntologyCellularComponentcentrosome

MISP DCDC2 CCDC8 AKAP9 CEP95 CEP250 NUMA1 CCDC18 CEP131 CEP152 PCNT

1.95e-067705111GO:0005813
GeneOntologyCellularComponentspindle pole centrosome

MISP CEP250 NUMA1

1.29e-0519513GO:0031616
GeneOntologyCellularComponentpericentriolar material

AKAP9 CEP152 PCNT

4.29e-0528513GO:0000242
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

NES MISP DCDC2 NUMA1 DNAH2 BYSL BFSP2 PPL KIF7 PCNT

5.28e-058995110GO:0099513
GeneOntologyCellularComponent3M complex

CCDC8 ANKRA2

5.81e-055512GO:1990393
GeneOntologyCellularComponentsupramolecular fiber

NES MISP DCDC2 SYNE1 NUMA1 DNAH2 BYSL BFSP2 PPL KIF7 PCNT

1.04e-0411795111GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

NES MISP DCDC2 SYNE1 NUMA1 DNAH2 BYSL BFSP2 PPL KIF7 PCNT

1.10e-0411875111GO:0099081
GeneOntologyCellularComponentciliary basal body

AKAP9 CEP250 CEP131 KIF7 PCNT

1.11e-04195515GO:0036064
GeneOntologyCellularComponentmitotic spindle astral microtubule

MISP NUMA1

1.62e-048512GO:0061673
GeneOntologyCellularComponentcentriolar satellite

DCDC2 CCDC18 CEP131 PCNT

2.68e-04128514GO:0034451
GeneOntologyCellularComponentmicrotubule

MISP DCDC2 NUMA1 DNAH2 BYSL KIF7 PCNT

2.95e-04533517GO:0005874
GeneOntologyCellularComponentastral microtubule

MISP NUMA1

3.16e-0411512GO:0000235
GeneOntologyCellularComponentaster

MISP NUMA1

3.79e-0412512GO:0005818
GeneOntologyCellularComponentlow-density lipoprotein particle

PLA2G7 APOBR

6.85e-0416512GO:0034362
GeneOntologyCellularComponentcentriole

CEP250 CEP131 CEP152 PCNT

8.18e-04172514GO:0005814
GeneOntologyCellularComponentcilium

DCDC2 AKAP9 CEP250 DNAH2 CEP131 ACE KIF7 PCNT

1.39e-03898518GO:0005929
GeneOntologyCellularComponentspindle pole

MISP CEP95 CEP250 NUMA1

1.57e-03205514GO:0000922
DomainPACT_domain

AKAP9 PCNT

7.60e-062522IPR019528
DomainPACT_coil_coil

AKAP9 PCNT

7.60e-062522PF10495
DomainG-protein_beta_WD-40_rep

TBL3 FBXW7 WDR48

1.71e-0385523IPR020472
DomainSpectrin_repeat

SYNE1 PPL

2.94e-0329522IPR002017
DomainSpectrin/alpha-actinin

SYNE1 PPL

3.57e-0332522IPR018159
DomainSPEC

SYNE1 PPL

3.57e-0332522SM00150
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

AKAP9 CEP250 NUMA1 CEP131 CEP152 PCNT

2.18e-0795396M6729
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

AKAP9 CEP250 CEP131 CEP152 PCNT

1.52e-0672395M27749
PathwayREACTOME_RECRUITMENT_OF_MITOTIC_CENTROSOME_PROTEINS_AND_COMPLEXES

AKAP9 CEP250 CEP131 CEP152 PCNT

2.73e-0681395M748
PathwayREACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION

AKAP9 CEP250 CEP131 CEP152 PCNT

3.89e-0687395M27194
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

AKAP9 CEP250 NUMA1 CEP131 CEP152

4.60e-0690395MM14979
PathwayREACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

AKAP9 CEP250 CEP131 CEP152 PCNT

6.65e-0697395M27478
PathwayREACTOME_MITOTIC_PROMETAPHASE

AKAP9 CEP250 NUMA1 CEP131 CEP152 PCNT

1.87e-05204396M4217
PathwayREACTOME_AURKA_ACTIVATION_BY_TPX2

AKAP9 CEP250 CEP131 CEP152

4.25e-0571394MM15495
PathwayREACTOME_REGULATION_OF_PLK1_ACTIVITY_AT_G2_M_TRANSITION

AKAP9 CEP250 CEP131 CEP152

8.62e-0585394MM14906
PathwayREACTOME_ANCHORING_OF_THE_BASAL_BODY_TO_THE_PLASMA_MEMBRANE

AKAP9 CEP250 CEP131 CEP152

1.38e-0496394MM15207
PathwayREACTOME_MITOTIC_G2_G2_M_PHASES

AKAP9 CEP250 CEP131 CEP152 PCNT

2.13e-04200395M864
PathwayREACTOME_CILIUM_ASSEMBLY

AKAP9 CEP250 CEP131 CEP152 PCNT

2.18e-04201395M27472
PathwayREACTOME_MITOTIC_PROMETAPHASE

AKAP9 CEP250 NUMA1 CEP131 CEP152

2.23e-04202395MM15362
PathwayBIOCARTA_AKAPCENTROSOME_PATHWAY

AKAP9 PCNT

4.84e-0412392MM1460
PathwayREACTOME_CELL_CYCLE

AKAP9 SYNE1 CEP250 POLR2D NUMA1 CEP131 CEP152 PCNT

5.24e-04694398M543
PathwayBIOCARTA_AKAPCENTROSOME_PATHWAY

AKAP9 PCNT

6.65e-0414392M15347
PathwayREACTOME_PHASE_2_PLATEAU_PHASE

CACNB2 AKAP9

6.65e-0414392MM15198
PathwayREACTOME_PHASE_2_PLATEAU_PHASE

CACNB2 AKAP9

7.65e-0415392M27456
PathwayREACTOME_M_PHASE

AKAP9 CEP250 NUMA1 CEP131 CEP152 PCNT

9.21e-04417396M27662
PathwayREACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE

AKAP9 CEP250 CEP131 CEP152 PCNT

1.28e-03297395M27050
PathwayREACTOME_MITOTIC_G2_G2_M_PHASES

AKAP9 CEP250 CEP131 CEP152

1.62e-03184394MM15145
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

AKAP9 CEP95 CEP250 CEP131 CEP152 PCNT

1.08e-0714654621399614
Pubmed

Proximity interactions among centrosome components identify regulators of centriole duplication.

CEP250 CEP131 CEP152 KIF7 PCNT

5.28e-0710154524613305
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NES CCDC8 AKAP9 CEP95 CGN CCDC18 CEP131 CEP152 ZNF598 WNK3

7.33e-07861541036931259
Pubmed

The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion.

AKAP9 CEP250 CEP131 PCNT

1.80e-065654411076968
Pubmed

The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation.

AKAP9 CEP250 CEP131 PCNT

1.93e-065754416462731
Pubmed

Polo-like kinase 1 regulates Nlp, a centrosome protein involved in microtubule nucleation.

AKAP9 CEP250 CEP131 PCNT

2.07e-065854412852856
Pubmed

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function.

AKAP9 CEP250 CEP131 PCNT

2.54e-06615447790358
Pubmed

Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3.

PLA2G7 DCDC2 BFSP2

3.37e-061954331847788
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

NES CCDC8 SYNE1 CGN NUMA1 CEP131 SRCAP TBL3 KIF7 PCNT

3.46e-061024541024711643
Pubmed

Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.

AKAP9 CEP250 CEP131 PCNT

3.48e-066654412221128
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

CCDC8 AKAP9 POLR2D CGN CCDC18 CEP131 KIF7 PCNT FBXW7 WDR48

4.28e-061049541027880917
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

GRIPAP1 CEP95 CEP250 CGN CEP152 ZNF598 ACE KIF7 PCNT

6.09e-0685354928718761
Pubmed

Killer-cell immunoglobulin-like receptors and falciparum malaria in southwest Nigeria.

KIR2DS3 KIR2DS5

7.09e-06354224929143
Pubmed

Activated ezrin controls MISP levels to ensure correct NuMA polarization and spindle orientation.

MISP NUMA1

7.09e-06354229669740
Pubmed

Apolipoprotein E, angiotensin-converting enzyme and alpha-1-antichymotrypsin genotypes are not associated with post-stroke dementia.

SERPINA3 ACE

7.09e-06354212736093
Pubmed

A novel surface molecule homologous to the p58/p50 family of receptors is selectively expressed on a subset of human natural killer cells and induces both triggering of cell functions and proliferation.

KIR2DS3 KIR2DS5

7.09e-0635428765026
Pubmed

Activating killer immunoglobulin-like receptor incompatibilities enhance graft-versus-host disease and affect survival after allogeneic hematopoietic stem cell transplantation.

KIR2DS3 KIR2DS5

7.09e-06354219500138
Pubmed

Hook3 interacts with PCM1 to regulate pericentriolar material assembly and the timing of neurogenesis.

NES PCNT

1.42e-05454220152126
Pubmed

Analysis of candidate genes and hypertension in African American adults.

SERPINA3 ACE

1.42e-05454219341158
Pubmed

Nesprin-1α-Dependent Microtubule Nucleation from the Nuclear Envelope via Akap450 Is Necessary for Nuclear Positioning in Muscle Cells.

AKAP9 SYNE1

1.42e-05454228966089
Pubmed

Neuroepithelial stem cell proliferation requires LIS1 for precise spindle orientation and symmetric division.

NES PCNT

1.42e-05454218267077
Pubmed

A role for KIR gene variants other than KIR2DS1 in conferring susceptibility to psoriasis.

KIR2DS3 KIR2DS5

1.42e-05454216829306
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

NES CACNB2 AKAP9 SYNE1 NUMA1 CEP131 WNK3 KIF7 PCNT

1.60e-0596354928671696
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

NES GRIPAP1 CGN NUMA1 PPL PCNT

2.00e-0536054633111431
Pubmed

In contrast to other stimulatory natural killer cell immunoglobulin-like receptor loci, several KIR2DS5 alleles predominate in African Americans.

KIR2DS3 KIR2DS5

2.36e-05554219410616
Pubmed

MDM1 is a microtubule-binding protein that negatively regulates centriole duplication.

CEP250 CEP152

2.36e-05554226337392
Pubmed

Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex.

NES PCNT

2.36e-05554220471352
Pubmed

The centriolar satellite protein Cep131 is important for genome stability.

CEP131 PCNT

2.36e-05554222797915
Pubmed

CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly.

AKAP9 NUMA1

2.36e-05554225657325
Pubmed

Periplakin interactions with lens intermediate and beaded filaments.

BFSP2 PPL

2.36e-05554219029034
Pubmed

Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly.

CEP131 CEP152 KIF7

2.87e-053854336674791
Pubmed

Conserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complex.

AKAP9 PCNT

3.54e-05654220466722
Pubmed

Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability.

CEP131 PCNT

3.54e-05654224816561
Pubmed

Cdk1/Erk2- and Plk1-dependent phosphorylation of a centrosome protein, Cep55, is required for its recruitment to midbody and cytokinesis.

AKAP9 PCNT

3.54e-05654216198290
Pubmed

The Plk1 target Kizuna stabilizes mitotic centrosomes to ensure spindle bipolarity.

AKAP9 PCNT

3.54e-05654216980960
Pubmed

Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.

GRIPAP1 CCDC18 CEP131 CEP152 KIF7

4.46e-0525154529778605
Pubmed

Human transcription factor protein interaction networks.

CCDC8 NUMA1 CEP131 CEP152 SRCAP TAF1L ZMYM4 KIF7 FBXW7 WDR48

6.10e-051429541035140242
Pubmed

The centrosomal protein pericentrin identified at the basal body complex of the connecting cilium in mouse photoreceptors.

AKAP9 PCNT

6.59e-05854222031837
Pubmed

CP110 cooperates with two calcium-binding proteins to regulate cytokinesis and genome stability.

AKAP9 PCNT

6.59e-05854216760425
Pubmed

NullHap--a versatile application to estimate haplotype frequencies from unphased genotypes in the presence of null alleles.

KIR2DS3 KIR2DS5

6.59e-05854218681957
Pubmed

Molecular clones of the p58 NK cell receptor reveal immunoglobulin-related molecules with diversity in both the extra- and intracellular domains.

KIR2DS3 KIR2DS5

8.46e-0595427749980
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR2DS3 KIR2DS5

8.46e-0595428662091
Pubmed

A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice.

NES AKAP9 PCNT

9.25e-055654320096683
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

CCDC8 FAT2 AKAP9 SYNE1

9.36e-0515254434299191
Pubmed

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.

KIR2DS3 KIR2DS5

1.06e-041054221206914
Pubmed

Assessment of killer cell immunoglobulinlike receptor expression and corresponding HLA class I phenotypes demonstrates heterogenous KIR expression independent of anticipated HLA class I ligands.

KIR2DS3 KIR2DS5

1.06e-041054212559621
Pubmed

Cell polarity and spindle orientation in the distal epithelium of embryonic lung.

NUMA1 PCNT

1.06e-041054221246661
Pubmed

Natural killer cells and immune surveillance.

KIR2DS3 KIR2DS5

1.29e-041154218830515
Pubmed

The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex.

NES PCNT

1.29e-041154219146812
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR2DS3 KIR2DS5

1.29e-041154219664392
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR2DS3 KIR2DS5

1.55e-041254220371502
Pubmed

The genetics of primary haemorrhagic stroke, subarachnoid haemorrhage and ruptured intracranial aneurysms in adults.

SERPINA3 ACE

1.55e-041254219008959
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR2DS3 KIR2DS5

1.55e-041254219181658
Pubmed

Novel embryonic neuronal migration and proliferation defects in Dcx mutant mice are exacerbated by Lis1 reduction.

NES PCNT

1.55e-041254220181597
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR2DS3 KIR2DS5

1.55e-041254220137308
Pubmed

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.

KIR2DS3 KIR2DS5

1.55e-041254219936734
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

GRIPAP1 AKAP9 CEP250 CEP131 ZNF598 TBL3 PCNT

1.60e-0475454733060197
Pubmed

CHIP as a membrane-shuttling proteostasis sensor.

SERPINA3 AKAP9 SRCAP

1.65e-046854329091030
Pubmed

Centriolar satellites assemble centrosomal microcephaly proteins to recruit CDK2 and promote centriole duplication.

CEP131 CEP152

1.83e-041354226297806
Pubmed

[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].

KIR2DS3 KIR2DS5

1.83e-041354218687225
Pubmed

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

KIR2DS3 KIR2DS5

1.83e-041354219934297
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR2DS3 KIR2DS5

1.83e-041354219120281
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

CEP250 BYSL CEP152 TBL3 PCNT

1.85e-0434054529478914
Pubmed

Mouse B-type lamins are required for proper organogenesis but not by embryonic stem cells.

NES PCNT

2.13e-041454222116031
Pubmed

Frequencies of killer immunoglobulin-like receptor genotypes influence susceptibility to spontaneous abortion.

KIR2DS3 KIR2DS5

2.13e-041454219875891
Pubmed

Multiple sclerosis associates with LILRA3 deletion in Spanish patients.

KIR2DS3 KIR2DS5

2.13e-041454219421224
Pubmed

Distribution of killer cell immunoglobulin-like receptor genes in the Chinese Han population.

KIR2DS3 KIR2DS5

2.13e-041454215896204
Pubmed

SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.

NES SYNE1

2.13e-041454219874786
Pubmed

CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion.

CEP152 PCNT

2.13e-041454232060285
Pubmed

Killer cell immunoglobulin-like receptor gene diversity in a Caucasian population of southern Brazil.

KIR2DS3 KIR2DS5

2.45e-041554220082646
Pubmed

Disparate distribution of activating and inhibitory killer cell immunoglobulin-like receptor genes in patients with systemic lupus erythematosus.

KIR2DS3 KIR2DS5

2.45e-041554219926642
Pubmed

Killer cell immunoglobulin-like receptors in HLA-B27-associated acute anterior uveitis, with and without axial spondyloarthropathy.

KIR2DS3 KIR2DS5

2.45e-041554219850842
Pubmed

Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma.

KIR2DS3 KIR2DS5

2.45e-041554220207982
Pubmed

Killer immunoglobulin-like receptors (KIR2DL2 and/or KIR2DS2) in presence of their ligand (HLA-C1 group) protect against chronic myeloid leukaemia.

KIR2DS3 KIR2DS5

2.45e-041554219493232
Pubmed

[Killer cell immunoglobin-like receptor and its ligand gene polymorphisms in Hunan Han patients with type 1 diabetes].

KIR2DS3 KIR2DS5

2.45e-041554220356536
Pubmed

N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis.

MYLK BFSP2

2.45e-041554228552735
Pubmed

Inhibitory KIR and specific HLA-C gene combinations confer susceptibility to or protection against chronic hepatitis B.

KIR2DS3 KIR2DS5

2.45e-041554220643584
Pubmed

KIR genes polymorphism in Argentinean Caucasoid and Amerindian populations.

KIR2DS3 KIR2DS5

2.45e-041554217498266
Pubmed

Killer cell immunoglobulin-like receptor genotype and killer cell immunoglobulin-like receptor-human leukocyte antigen C ligand compatibility affect the severity of hepatitis C virus recurrence after liver transplantation.

KIR2DS3 KIR2DS5

2.45e-041554219326408
Pubmed

The COPD genetic association compendium: a comprehensive online database of COPD genetic associations.

SERPINA3 ACE

2.80e-041654219933216
Pubmed

Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals.

KIR2DS3 KIR2DS5

2.80e-041654219897003
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Java, Kalimantan, Timor and Irian Jaya.

KIR2DS3 KIR2DS5

2.80e-041654219000141
Pubmed

Diversity of killer cell immunoglobulin-like receptor genes in Indonesian populations of Sumatra, Sulawesi and Moluccas Islands.

KIR2DS3 KIR2DS5

2.80e-041654220670355
Pubmed

Activating killer cell immunoglobulin-like receptor genes' association with recurrent miscarriage.

KIR2DS3 KIR2DS5

2.80e-041654219527230
Pubmed

Polymorphisms of KIR gene and HLA-C alleles: possible association with susceptibility to HLA-B27-positive patients with ankylosing spondylitis.

KIR2DS3 KIR2DS5

2.80e-041654220652381
Pubmed

Asian population frequencies and haplotype distribution of killer cell immunoglobulin-like receptor (KIR) genes among Chinese, Malay, and Indian in Singapore.

KIR2DS3 KIR2DS5

2.80e-041654218668235
Pubmed

Strabismus regulates asymmetric cell divisions and cell fate determination in the mouse brain.

NES NUMA1

2.80e-041654219332887
Pubmed

Influence of activating and inhibitory killer immunoglobulin-like receptors on predisposition to recurrent miscarriages.

KIR2DS3 KIR2DS5

2.80e-041654219279038
Pubmed

No association of KIR genes with Behcet's disease.

KIR2DS3 KIR2DS5

2.80e-041654217868255
Pubmed

A study of the killer cell immunoglobulin-like receptor gene KIR2DS1 in a Caucasoid Brazilian population with psoriasis vulgaris.

KIR2DS3 KIR2DS5

2.80e-041654218643961
Pubmed

Distribution of killer cell immunoglobulin-like receptor (KIR) genotypes in patients with familial Mediterranean fever.

KIR2DS3 KIR2DS5

2.80e-041654219309280
Pubmed

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice.

NES PCNT

2.80e-041654215037549
Pubmed

Report from the killer immunoglobulin-like receptor (KIR) anthropology component of the 15th International Histocompatibility Workshop: worldwide variation in the KIR loci and further evidence for the co-evolution of KIR and HLA.

KIR2DS3 KIR2DS5

2.80e-041654220331834
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].

KIR2DS3 KIR2DS5

2.80e-041654216403292
Pubmed

HLA-DQA1*0505 sharing and killer immunoglobulin-like receptors in sub fertile couples: report from the 15th International Histocompatibility Workshop.

KIR2DS3 KIR2DS5

2.80e-041654220210919
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

BDP1 GRIPAP1 CEP131 SRCAP ZMYM4 PCNT

2.95e-0458854638580884
Pubmed

Natural killer cell receptor repertoire and their ligands, and the risk of CMV infection after kidney transplantation.

KIR2DS3 KIR2DS5

3.17e-041754219032228
Pubmed

The beneficial impact of missing KIR ligands and absence of donor KIR2DS3 gene on outcome following unrelated hematopoietic SCT for myeloid leukemia in the Chinese population.

KIR2DS3 KIR2DS5

3.17e-041754220173784
Pubmed

The role of killer immunoglobulin-like receptor haplotypes on the outcome of unrelated donor haematopoietic SCT for thalassaemia.

KIR2DS3 KIR2DS5

3.17e-041754220173792
Pubmed

Role of killer cell immunoglobulin-like receptor gene content and human leukocyte antigen-C group in susceptibility to human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis in Peru.

KIR2DS3 KIR2DS5

3.17e-041754220483367
InteractionCEP135 interactions

AKAP9 CEP95 CEP250 CGN CCDC18 CEP131 CEP152 ZMYM4 KIF7 PCNT

2.41e-092725410int:CEP135
InteractionSASS6 interactions

CEP250 CGN CCDC18 CEP131 CEP152 KIF7 PCNT FBXW7

9.62e-09159548int:SASS6
InteractionKRT8 interactions

NES GRIPAP1 AKAP9 USP32 CCDC18 BYSL CEP131 CEP152 PPL KIF7 PCNT

2.00e-084415411int:KRT8
InteractionWHAMMP3 interactions

AKAP9 CEP95 SYNE1 CEP250 CEP131 CEP152 PCNT

2.95e-08119547int:WHAMMP3
InteractionCEP63 interactions

SYNE1 CCDC18 CEP131 CEP152 BFSP2 KIF7 PCNT

4.83e-07179547int:CEP63
InteractionSTIL interactions

AKAP9 CGN CCDC18 CEP131 CEP152 KIF7 PCNT

7.22e-07190547int:STIL
InteractionNDC80 interactions

AKAP9 CEP95 CEP250 CCDC18 CEP131 CEP152 KIF7 PCNT

1.69e-06312548int:NDC80
InteractionAMOT interactions

CCDC8 CEP250 CGN CCDC18 CEP131 CEP152 KIF7 PCNT

1.69e-06312548int:AMOT
InteractionPCM1 interactions

CCDC8 AKAP9 CEP95 CEP250 CCDC18 CEP131 CEP152 KIF7 PCNT

2.07e-06434549int:PCM1
InteractionTPTE2 interactions

AKAP9 CCDC18 CEP131 KIF7 PCNT

3.00e-0684545int:TPTE2
InteractionPLK4 interactions

CEP250 CGN CEP131 CEP152 ACE PCNT

3.45e-06154546int:PLK4
InteractionPCNT interactions

CCDC8 AKAP9 SYNE1 CCDC18 CEP131 CEP152 PCNT

3.52e-06241547int:PCNT
InteractionOBSL1 interactions

NES MISP CCDC8 ANKRA2 SYNE1 ECM2 CGN NUMA1 BYSL SRCAP TBL3 PCNT

3.62e-069025412int:OBSL1
InteractionTMOD1 interactions

CCDC18 LSP1 CEP131 CEP152 PCNT FBXW7

4.45e-06161546int:TMOD1
InteractionCCDC183 interactions

GRIPAP1 CEP131 BFSP2 PCNT

5.77e-0644544int:CCDC183
InteractionFAM167A interactions

NES CEP250 CCDC18 PPL FBXW7

5.81e-0696545int:FAM167A
InteractionKRT19 interactions

AKAP9 USP32 CCDC18 CEP131 CEP152 KIF7 PCNT

9.84e-06282547int:KRT19
InteractionBFSP1 interactions

CCDC18 BYSL BFSP2 PPL

1.13e-0552544int:BFSP1
InteractionKRT18 interactions

NES CCDC8 USP32 CCDC18 CEP131 CEP152 KIF7 PCNT

1.47e-05419548int:KRT18
InteractionDVL2 interactions

CCDC8 FAT2 AKAP9 SYNE1 USP32 NUMA1 BYSL ZNF598 WDR48

1.55e-05557549int:DVL2
InteractionUSO1 interactions

GRIPAP1 AKAP9 DNAH2 BYSL ZNF488 PCNT

2.32e-05215546int:USO1
InteractionCCDC14 interactions

CCDC18 CEP131 CEP152 KIF7 PCNT

2.45e-05129545int:CCDC14
InteractionNINL interactions

CEP95 CEP250 CEP131 CEP152 ZNF598 ACE KIF7 PCNT

2.78e-05458548int:NINL
InteractionCCDC18 interactions

CEP250 CCDC18 KIF7 PCNT

3.30e-0568544int:CCDC18
InteractionMAPRE3 interactions

DCDC2 AKAP9 CEP131 ZNF598 KIF7 PCNT

3.38e-05230546int:MAPRE3
InteractionFAM184A interactions

CCDC18 CEP131 KIF7 PCNT

4.14e-0572544int:FAM184A
InteractionSEPTIN10 interactions

AKAP9 CEP131 CEP152 KIF7 PCNT

4.15e-05144545int:SEPTIN10
InteractionSDR42E2 interactions

MYLK NUMA1

4.21e-054542int:SDR42E2
InteractionNIN interactions

CEP95 CEP250 CEP131 CEP152 ZNF598 KIF7 PCNT

4.63e-05359547int:NIN
InteractionPNMA2 interactions

MISP CCDC8 BYSL CEP131 KIF7 WDR48

5.51e-05251546int:PNMA2
InteractionAP2B1 interactions

AKAP9 CCDC18 CEP131 CEP152 WNK3 PCNT FBXW7

5.89e-05373547int:AP2B1
InteractionNDEL1 interactions

GRIPAP1 AKAP9 SYNE1 CCDC18 CEP152

7.69e-05164545int:NDEL1
InteractionKRT23 interactions

NES GRIPAP1 CEP250

7.75e-0531543int:KRT23
InteractionCEP290 interactions

CCDC8 CCDC18 CEP131 KIF7 PCNT

1.16e-04179545int:CEP290
InteractionSSX2IP interactions

CEP250 NUMA1 BYSL CEP131 KIF7 PCNT

1.17e-04288546int:SSX2IP
InteractionYWHAH interactions

NES CCDC8 AKAP9 CEP95 CGN CCDC18 CEP131 CEP152 WNK3 KIF7 PCNT

1.36e-0411025411int:YWHAH
InteractionDISC1 interactions

GRIPAP1 AKAP9 SYNE1 BFSP2 KIF7 PCNT FBXW7

1.41e-04429547int:DISC1
InteractionCDK5RAP2 interactions

AKAP9 CCDC18 CEP131 CEP152 PCNT

1.54e-04190545int:CDK5RAP2
InteractionSPICE1 interactions

CEP95 CEP250 CEP131 KIF7 PCNT

1.57e-04191545int:SPICE1
InteractionLATS1 interactions

AKAP9 CGN CCDC18 CEP131 CEP152 KIF7 PCNT

1.65e-04440547int:LATS1
InteractionRPAP1 interactions

CCDC8 POLR2D NUMA1 FBXW7

1.80e-04105544int:RPAP1
InteractionRALBP1 interactions

NES CEP250 WNK3 PPL KIF7

1.86e-04198545int:RALBP1
InteractionMED4 interactions

POLR2D CCDC18 CEP131 CEP152 KIF7 PCNT FBXW7

1.89e-04450547int:MED4
InteractionCEP131 interactions

CCDC8 CEP131 CEP152 KIF7 PCNT

1.95e-04200545int:CEP131
InteractionPXN interactions

AKAP9 CCDC18 CEP131 CEP152 KIF7 PCNT

2.62e-04334546int:PXN
InteractionFTL interactions

DCDC2 CEP95 CEP250 POLR2D SRCAP PCNT

3.26e-04348546int:FTL
InteractionCCDC8 interactions

CCDC8 ANKRA2 CEP250 CGN NUMA1 CEP131 KIF7 PCNT

3.35e-04656548int:CCDC8
InteractionDCTN2 interactions

AKAP9 POLR2D CEP131 CEP152 ZNF598 PCNT

3.68e-04356546int:DCTN2
InteractionSYCE1 interactions

AKAP9 CCDC18 CEP152 BFSP2

3.73e-04127544int:SYCE1
InteractionANAPC2 interactions

CCDC18 CEP131 CEP152 KIF7 PCNT

4.02e-04234545int:ANAPC2
InteractionDYNLL1 interactions

AKAP9 NUMA1 CCDC18 CEP131 CEP152 ZMYM4 PCNT

4.04e-04510547int:DYNLL1
InteractionYWHAE interactions

CCDC8 AKAP9 CEP95 CEP250 POLR2D CGN CCDC18 CEP131 ZNF598 FBXW7 WDR48

4.22e-0412565411int:YWHAE
InteractionMAPRE1 interactions

MISP AKAP9 CEP250 NUMA1 CEP131 ZNF598 PCNT

4.23e-04514547int:MAPRE1
InteractionEBF2 interactions

NES SERPINA3 PPL

5.32e-0459543int:EBF2
InteractionPHLDB2 interactions

CCDC8 CEP250 CGN KIF7

5.84e-04143544int:PHLDB2
InteractionDCPS interactions

CEP250 BYSL CEP152 TBL3 PCNT FBXW7

6.29e-04394546int:DCPS
InteractionKIF7 interactions

CCDC8 CCDC18 CEP131 KIF7

6.31e-04146544int:KIF7
InteractionDYRK1A interactions

BDP1 CCDC8 USP32 CEP131 PPL PCNT FBXW7

6.46e-04552547int:DYRK1A
InteractionCEP350 interactions

CCDC8 CEP250 CEP152 PCNT

6.81e-04149544int:CEP350
InteractionGIGYF2 interactions

CCDC8 CEP250 CGN ZNF598 FBXW7

6.84e-04263545int:GIGYF2
Cytoband17q23.3

CEP95 USP32 ACE

6.11e-063054317q23.3
CytobandEnsembl 112 genes in cytogenetic band chr17q23

CEP95 USP32 ACE

3.92e-04120543chr17q23
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR2DS3 KIR2DS5

5.46e-0418352620
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#1

BDP1 CACNB2 ZNF182 AKAP9 CEP95 CEP250 NUMA1 ZMYM4 KIF7 FBXW7

1.38e-057805110Facebase_RNAseq_e10.5_Lateral Nasal Eminence_2500_K1
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNB2 FAT2 MYLK FGF18 KIF7

9.73e-071535251524557514668f515ac1bbe847611f564b265b42
ToppCellE17.5-Mesenchymal-myocytic_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NES CACNB2 MYLK LSP1 FGF18

3.20e-0619552501a750d660993017af00736215cbcff2de5909c1
ToppCelldroplet-Kidney-nan-24m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 DNAH2 LSP1 ACE

4.31e-051675242ee1660be117e20f24557522345572d11cbee813
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium-7|TCGA-Endometrium / Sample_Type by Project: Shred V9

CACNB2 KLHDC1 MYLK ECM2

4.42e-05168524a97e8e07ba949b30805aeed5f60fa5e092b9d3d4
ToppCell390C-Lymphocytic-NK_cells-NK_cell_C|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NES FAT2 APOBR WNK3

4.62e-0517052481341bf4fe090af70b2091b6b2579ed08d76e22d
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue-Endometrium|TCGA-Endometrium / Sample_Type by Project: Shred V9

CACNB2 KLHDC1 MYLK ECM2

4.62e-05170524cdc19013da7c41d1ed8400a6a643e4c684ff9912
ToppCellTCGA-Endometrium-Solid_Tissue_Normal|TCGA-Endometrium / Sample_Type by Project: Shred V9

CACNB2 KLHDC1 MYLK ECM2

4.62e-051705240bde0a40440c7fdf7ba89cac8831d4014e7a4807
ToppCellTCGA-Endometrium-Solid_Tissue_Normal-Endometrium_normal_tissue|TCGA-Endometrium / Sample_Type by Project: Shred V9

CACNB2 KLHDC1 MYLK ECM2

4.62e-05170524516b38c4ecf6b0b04c5d4f80c510dcc00b328c6f
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MYLK ABCB6 LSP1 KIF7

5.06e-05174524c529f3674b784f872f4387ffdeb46aecb619976b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT2 SLC24A2 ZNF598 PPL

5.06e-05174524207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECM2 LSP1 ACE FGF18

6.16e-051835245cfcd589a480e67654d3d94e71916f122150db10
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECM2 LSP1 ACE FGF18

6.16e-05183524c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCellfacs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ECM2 LSP1 ACE FGF18

6.16e-0518352481003ddc24164959dd41bb12fcac72638789b8f2
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_arterial_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NES RBM44 SYNE1 FGF18

6.42e-05185524fa94c4a1660967f211ba095606cd0aa37d38e17a
ToppCellControl-T_cells-Cycling_NK/T_cells|Control / group, cell type (main and fine annotations)

CCDC18 CEP152 BFSP2 KIF7

6.42e-051855249766216b41ee62bbac4caa25cb98ec5627a24075
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 MYLK SYNE1 FGF18

6.42e-05185524e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCellE16.5-samps-Mesenchymal-Myofibroblast|E16.5-samps / Age Group, Lineage, Cell class and subclass

CACNB2 MYLK LSP1 FGF18

6.56e-05186524e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell3'-Adult-Appendix-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NES RBM44 SYNE1 FGF18

6.69e-0518752437d8ee5c8bd6324749e5a2adef1d0482c75da80c
ToppCell3'-Adult-Appendix-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NES RBM44 SYNE1 FGF18

6.69e-05187524ec98d5e480b08854dfd0ba6b1dc6610455f90640
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 MYLK SYNE1 FGF18

6.83e-051885243177b2c1723268d330d3e9f24f9e24492ace6286
ToppCellControl-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

NES MYLK SYNE1 ACE

6.83e-0518852488b3415e33db81726dd29c1f50c886e057af50a0
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

NES MYLK SYNE1 ACE

6.83e-051885241aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like_Prolif-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

AKAP9 LINC00471 CCDC18 CEP152

6.83e-051885240476d7ee3e0ce78c3c5b111e9ade01098f9ea7ec
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC8 SLC24A2 ECM2 PPL

6.98e-05189524a5306561026e4dfcc39beeb785e5108ac595d136
ToppCellfacs-Kidney-nan-3m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC8 SLC24A2 ECM2 PPL

6.98e-05189524381058f55908f84375b54601d617389ef43ab855
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 MYLK SYNE1 FGF18

6.98e-051895247ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellfacs-Kidney-nan-3m-Mesenchymal-mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC8 SLC24A2 ECM2 PPL

6.98e-05189524302b950a6ad578f8aeff7ea6fd15fe631225287d
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 MYLK SYNE1 FGF18

7.27e-051915247853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

BDP1 DCDC2 AKAP9 ANKRA2

7.41e-05192524916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell11.5-Airway-Epithelial-Bud_tip_adjacent|Airway / Age, Tissue, Lineage and Cell class

MISP DCDC2 CGN PPL

7.41e-05192524fbb34a959b9bd9cb72a5195a07f4653a957e4ca8
ToppCellPCW_13-14-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MISP DCDC2 CGN PPL

7.41e-05192524b73f24d1c55dfef1eb01c26da117dbf637ea080a
ToppCellE15.5-Mesenchymal-myocytic_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYLK SYNE1 LSP1 FGF18

7.56e-051935243316d6a39abb6a518d45b846254325fc7a8b2035
ToppCellE15.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYLK SYNE1 LSP1 FGF18

7.56e-05193524e787e618f6e8a1e22be366ce606bf78831b60a90
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

BDP1 DCDC2 AKAP9 ANKRA2

7.56e-05193524e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellIPF-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

NES MYLK SYNE1 ACE

7.72e-05194524777ce41c3f22c591e2d81120f189b834e53ffb4b
ToppCellPCW_13-14-Epithelial-Epithelial_airway|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MISP DCDC2 CGN PPL

7.72e-051945247b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CEP95 CCDC18 CEP152 PCNT

7.72e-05194524dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MYLK LSP1 FGF18

7.87e-05195524b0d408f8bc1701a87596ed55efcd90749fee33e6
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CACNB2 MYLK FGF18 NSMCE4A

7.87e-051955244dba732c8d8ecf0ed9ece1814dc4060402199ed9
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MISP DCDC2 CGN PPL

7.87e-05195524d67a2b489c29bfd575751c13d2a5b1efdec5240a
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MYLK LSP1 FGF18

7.87e-051955242514c1f23424b5fc664d326d31ffd22bafe74ef8
ToppCellE17.5-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CACNB2 MYLK LSP1 FGF18

7.87e-051955241daddd801bd4596fffbdb822fc326d5127c96004
ToppCellFibroblast-B_(Myofibroblast)|World / shred on cell class and cell subclass (v4)

NES MYLK LSP1 FGF18

7.87e-05195524a8d6416518f226e1ec2d6bdc9d4b90cef5cb1365
ToppCellE18.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MYLK LSP1 FGF18

7.87e-05195524a486a7acea0e91048cc48afa0dbd3926d30bc217
ToppCellCOPD-Stromal-Myofibroblast|COPD / Disease state, Lineage and Cell class

SERPINA3 CACNB2 MYLK ECM2

8.03e-05196524af206bb5bbb8b604a6212acd79878bcc3d326cec
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MYLK LSP1 FGF18

8.03e-05196524e4d04e1f82779e8afd4e32bbe38d1d3f6f64ab50
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MYLK LSP1 FGF18

8.03e-05196524f0fd7db22985d2bc84dc8bcbdb2d552e280121dd
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SERPINA3 CACNB2 MYLK ECM2

8.03e-0519652442e9828222a9663525d571633e8a454c30bfa7f8
ToppCellP07-Mesenchymal-myocytic_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NES MYLK LSP1 FGF18

8.19e-05197524378299fe2ec6ed2fc858febb78ff1ac0898e457d
ToppCellCOPD-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

SERPINA3 CACNB2 MYLK ECM2

8.19e-05197524d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MYLK LSP1 FGF18

8.19e-0519752426475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCellP03-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NES MYLK LSP1 FGF18

8.19e-051975242cec938caf6ffd031cea37277071487e59b2c71c
ToppCellP03-Mesenchymal-myocytic_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NES MYLK LSP1 FGF18

8.19e-05197524079db904a08743b3c555cb7b3f5fb5c978dde25a
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MYLK LSP1 FGF18

8.19e-051975249d7a1c7dc70ba5e35645f19f9e056e4fa2494aa0
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MYLK LSP1 FGF18

8.19e-05197524090a251194da3e2806989d9a522588f83f52da7f
ToppCellCOPD-Stromal|COPD / Disease state, Lineage and Cell class

SERPINA3 CACNB2 MYLK ECM2

8.19e-05197524d5390d86acaa8c39f1da893e8d2271f9ed2951d7
ToppCellP07-Mesenchymal-myocytic_cell-aortic_smooth_muscle_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NES MYLK LSP1 FGF18

8.19e-05197524b1135378d768fbbe62a75747d1e8653d35252187
ToppCellH1299-infected-SARSCoV2|infected / Cell line, Condition and Strain

BDP1 AKAP9 CCDC18 CEP152

8.19e-051975240fa3e4cf93e77d78b1f97b906c5b13ca741ae17e
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MYLK LSP1 FGF18

8.19e-0519752443b5f8e917506c1717f9311584901b506ffd2c79
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MYLK LSP1 FGF18

8.19e-05197524155e63b33302a87393ace699b2f6d73abe9c5763
ToppCelldistal-3-mesenchymal-Fibromyocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACNB2 MYLK ECM2 FGF18

8.35e-05198524dc93886439a378a0c71e99acb8081bfb6b6d467b
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CACNB2 MYLK FGF18 NSMCE4A

8.35e-051985242d0c14f8cabab99bc6d7c27685437c78841c7245
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NES MYLK LSP1 FGF18

8.35e-05198524a4005a49cf6709b543994ceb51ecd5dc46197fa9
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

SERPINA3 CACNB2 MYLK ECM2

8.35e-05198524300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCelldistal-mesenchymal-Fibromyocyte-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACNB2 MYLK ECM2 FGF18

8.35e-051985249d1d95e7703cfc70a8ad427e400c340dbd205db8
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNB2 MYLK SLC24A2 FGF18

8.35e-05198524e9f434bfd072e590fe44d518057ee5aa653038f3
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

MISP DCDC2 CGN PPL

8.35e-05198524c477405b093f4e5374e57bcacf1fb204a0f7eb3b
ToppCellPCW_10-12-Epithelial-Epithelial_airway|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MISP DCDC2 CGN PPL

8.35e-051985249a12e5e47236433e512c668005fe3f8be6fde95c
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNB2 MYLK SLC24A2 SYNE1

8.35e-0519852422e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCelldistal-mesenchymal-Fibromyocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CACNB2 MYLK ECM2 FGF18

8.35e-05198524fbfac1d10e4224990a094cc84b74bbc206881423
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

MISP DCDC2 CGN PPL

8.51e-05199524af664e0d41a889a75dbf6cf0d50acd26f5ab3a3a
ToppCell11.5-Airway-Mesenchymal-Airway_Smooth_Muscle|Airway / Age, Tissue, Lineage and Cell class

NES MYLK SLC24A2 FGF18

8.51e-051995241a8c77d241bd817a195e1532fd25f51358cb1ff1
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NES MYLK SYNE1 ACE

8.68e-052005243767abc75176779198505ebc6967d55ce322d9fe
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FAT2 AKAP9 CGN PPL

8.68e-0520052497f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FAT2 AKAP9 CGN PPL

8.68e-05200524ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Tmsb4x_(Tmsb4x)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCB6 ZNF488 BFSP2

1.39e-0486523db67c05c876a5649371c0dc6c941cc371bc2feb8
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P2-Tnr-Polydendrocyte.Tnr.Tmsb4x_(Tmsb4x)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ABCB6 ZNF488 BFSP2

1.39e-04865232778446e035c5585bce28ed0ef93b87b6ad90c6e
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PLA2G7 MYLK FGF18

2.37e-04103523780a94c27ac3eb138a9f284251ae094d3e97ce71
ToppCellMyeloid-C_(Cd16+_Monocyte)|World / shred on cell class and cell subclass (v4)

PLA2G7 LSP1 APOBR

4.19e-04125523c73a77340e79f73fd1f900724e82a94d82e6b1bf
ToppCellLPS-antiTNF-Unknown-Endothelial-Monocytes-Macrophages|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NES CCDC18 CEP152

6.07e-04142523b66f9602dba30d1d4fbcc49ceb112eb5bd916ba1
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LSP1 ACE APOBR

6.85e-0414852312fa2c4922f03803006c606b1b16e79441e3bb13
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLA2G7 SYNE1 APOBR

6.85e-0414852374f1f9d1a53dc1a09cb6a504cbbdc7496c5b6879
ToppCellPND01-03-samps-Myeloid-Granulocyte|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PLA2G7 LSP1 APOBR

6.98e-041495237bdb396de8a1ef27ab0c2aaf1452576f4b0b5561
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PLA2G7 ZNF182 FGF18

6.98e-04149523a6c24d8f3b5f08587f0a12cd63d166b68ea000c7
ToppCellPND01-03-samps-Myeloid-Granulocyte-neutrophil__Lgals3-negative|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PLA2G7 LSP1 APOBR

6.98e-0414952350f53018e525b3d252caa8bed9e075b1bb1086dd
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLA2G7 SYNE1 APOBR

6.98e-041495234de52569611e63a780cde9bd111d6d9c11a05a11
ToppCellPND01-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLA2G7 SYNE1 APOBR

6.98e-04149523c957ac23ad6343eacce7e6be4a6d3ac043af4f86
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____macrophage|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 ACE APOBR

7.12e-0415052334774b015adecc2be56a471fda8994e89a6ad93e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SERPINA3 DCDC2 FGF18

7.54e-0415352379c4f4ccdc8249c8461075c73491bc3b2d13344a
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT1_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

MISP RBM44 CGN

7.69e-041545238a643d91896af9b630a715fb284c1523d01ad1a3
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_3|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PLA2G7 FGF18 WNK3

7.98e-04156523fc8b8aef29d6d1c0f0c1d08280d8aaff8d30535e
ToppCell(6)_Endothelial_cells-(6)_Endothelial-C_(Capillary_Aerocyte_)|(6)_Endothelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

MYLK SYNE1 ACE

8.13e-0415752384f629b7f589ca8a1abc220fa740c4a6fdc1b579
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LSP1 APOBR KIF7

8.13e-04157523d12f343454202da86a06d0369f8ffe5662cd091b
ToppCellfacs-Brain_Myeloid-Striatum_-18m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 MISP SYNE1

8.13e-041575239d4308312301cb922f156a7b6aededc9e1c62807
ToppCellHealthy/Control-Treg|Healthy/Control / Disease group and Cell class

CGN BFSP2 PPL

8.43e-0415952316a322760c99f3e2c3b73cbb399f77868951d3cb
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLA2G7 LSP1 APOBR

8.58e-04160523741e3b3f4ec5c77752da54746451f332435226e3
ToppCellfacs-Lung-Endomucin_-18m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 USP32 APOBR

8.74e-04161523e227f7b711475624cf80e77f235b1783d88d57b4
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 SYNE1 ACE

8.74e-041615233f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCellHealthy/Control-Treg|World / Disease group and Cell class

CGN BFSP2 PPL

8.74e-04161523457297cda5c9cee3bcc069fdecbbe24def027e5f
ToppCellfacs-Pancreas-Exocrine-18m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLA2G7 LSP1 APOBR

8.74e-0416152316f77e7a5444d2f2b210362816cd7a07b9b42af6
DiseaseSeckel syndrome 1

CEP152 PCNT

8.10e-063492C4551474
Diseaseproteinuria (is_implicated_in)

PLA2G7 ACE

5.64e-057492DOID:576 (is_implicated_in)
DiseaseSeckel syndrome

CEP152 PCNT

6.11e-0422492C0265202
Diseasenephrosis (biomarker_via_orthology)

NES ACE

6.11e-0422492DOID:2527 (biomarker_via_orthology)
Diseasecoronary artery disease (is_implicated_in)

PLA2G7 MYLK ACE

6.21e-04100493DOID:3393 (is_implicated_in)
DiseaseCoronary heart disease

PLA2G7 ACE

7.28e-0424492C0010068
Diseasecongenital diaphragmatic hernia (biomarker_via_orthology)

ACE KIF7

7.28e-0424492DOID:3827 (biomarker_via_orthology)
DiseaseBrugada Syndrome (disorder)

CACNB2 AKAP9

7.28e-0424492C1142166
DiseaseColorectal Carcinoma

CACNB2 AKAP9 SYNE1 ABCB6 ZMYM4 FBXW7

1.04e-03702496C0009402
DiseaseIgA glomerulonephritis (is_implicated_in)

PLA2G7 ACE

1.14e-0330492DOID:2986 (is_implicated_in)
Diseaseleft ventricular mass index

CACNB2 LSP1

1.46e-0334492EFO_0009290

Protein segments in the cluster

PeptideGeneStartEntry
TERNENQEESSQEVH

BDP1

2186

A6H8Y1
EQAIDREHERDVFQQ

AKAP9

2071

Q99996
EEIHRIQEQNEQDYR

CEP152

966

O94986
HDTNITAENARRQEE

ACE

71

P12821
EENLTQENQDRGTHV

SERPINA3

31

P01011
LQVHEEDQDVERSQV

ABCB6

216

Q9NP58
ATRIEQENVINHTDE

ANKRA2

166

Q9H9E1
EIRAEAEQQQQERAH

BFSP2

376

Q13515
DRESHQENEDRNSEL

LINC00471

56

Q8N535
DVDREQDHNECNKQR

CACNB2

611

Q08289
ADAEQDNQRAHDVDV

RBM44

711

Q6ZP01
VQRDIVQETQREEDH

MISP

351

Q8IVT2
QHTEEAIRQQEVEQL

MYLK

881

Q15746
EQQDTHELAVEVRDN

FAT2

2031

Q9NYQ8
DHQRQDQLREKQEEE

PPL

1076

O60437
VAEENVDFRIHVENQ

FGF18

26

O76093
REEQHQQQIAFSELE

KIF7

1111

Q2M1P5
ENQSHETLERENQEC

NES

561

P48681
RTVNREDSDEQDHQE

KIR2DS3

286

Q14952
AEREHEREEFQQEIQ

PCNT

1486

O95613
QEEETHIRNEQVRQR

PLA2G7

211

Q13093
RTVNREDSDEQDHQE

KIR2DS5

286

Q14953
AEARHQQVQAQREIE

CCDC18

1151

Q5T9S5
AEQAQEHEVETRALQ

CEP250

1911

Q9BV73
RQQEEEHTARNGEVV

FBXW7

46

Q969H0
RSQEDDAHNVQAVID

CEP95

56

Q96GE4
AHQQQRQGREEEEDE

ECM2

261

O94769
CQHERDRQLQAQDEE

LSP1

36

P33241
AAANHREEQRVQKEE

KLHDC1

381

Q8N7A1
QDVRDQLEQAQEERD

GRIPAP1

566

Q4V328
SEVTDNQREEAVHDQ

CCDC8

401

Q9H0W5
EFEEDQREHRAAVQQ

DNAH2

776

Q9P225
VTEEEAERFIHQVNQ

CEP131

256

Q9UPN4
QARQQQEELEAEHGT

BYSL

61

Q13895
EQVEEILDHSEQQAR

DCDC2

386

Q9UHG0
TARQEQHEAQAQVAE

NUMA1

661

Q14980
LEHRKQQNESAEDEQ

POLR2D

41

O15514
REEITVQQVHEETAN

SYNE1

426

Q8NF91
VDENERQNGAANHVE

SLC24A2

396

Q9UI40
DINEVAEDESQRHQQ

TAF1L

111

Q8IZX4
EENEGFEHNTQVRNQ

NSMCE4A

336

Q9NXX6
EEQQEGNDAEAQRRE

SRCAP

306

Q6ZRS2
DRSGQAQERQESHEQ

APOBR

151

Q0VD83
AQERQESHEQEVNRE

APOBR

156

Q0VD83
EEVASRDQEVEHVRQ

CGN

506

Q9P2M7
RDQEVEHVRQQYQRD

CGN

511

Q9P2M7
AQREVEEQHEVNEQL

CGN

1131

Q9P2M7
RQVDAQAQEREHDDP

ZNF488

111

Q96MN9
VDEQIERQHQDDQDK

ZNF182

101

P17025
ENEVNHVNGEQENRV

WDR48

486

Q8TAF3
TEAEQAEEQARQEEQ

TBL3

636

Q12788
AEEEHRQQEAERQKS

ZC3H11B

411

A0A1B0GTU1
QQQEEARRSEDQEEG

ZNF598

356

Q86UK7
QNRQRRDRQTHEDEQ

RPTN

766

Q6XPR3
VDEHESVEQSRRAQA

USP32

1216

Q8NFA0
RVTQHESDNENEIQI

ZMYM4

116

Q5VZL5
AECEETEVDQHVRQQ

WNK3

536

Q9BYP7