Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDUF2075

SLFN11 SLFN13

1.55e-053432IPR018647
DomainDUF2075

SLFN11 SLFN13

1.55e-053432PF09848
DomainAlbA_2

SLFN11 SLFN13

1.08e-047432PF04326
DomainSchlafen

SLFN11 SLFN13

1.08e-047432IPR029684
DomainSchlafen_AAA_dom

SLFN11 SLFN13

1.08e-047432IPR007421
DomainP-loop_NTPase

NDST1 SLFN11 MYO1A RAB37 DNAH5 SLFN13 HNRNPU DDX54

6.16e-04848438IPR027417
Domain-

NDST1 SLFN11 RAB37 DNAH5 SLFN13 HNRNPU DDX54

1.45e-037464373.40.50.300
DomainIntegrin_dom

ITGA4 ITGB8

1.50e-0325432IPR032695
DomainProtein_kinase_ATP_BS

MOK PLK2 BUB1 EPHA5

1.10e-02379434IPR017441
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

MYO1A DTHD1 SUGCT ADCY6 FER1L6 HNRNPU VDAC3 EML6 SHB HNRNPM VPS13A

1.30e-061442441135575683
Pubmed

Mouse Slfn8 and Slfn9 genes complement human cells lacking SLFN11 during the replication stress response.

SLFN11 SLFN13

1.56e-06244237833372
Pubmed

Interaction of Human OATP1B1 with PDZK1 Is Required for Its Trafficking to the Hepatocyte Plasma Membrane.

SLCO1B1 PDZK1

1.56e-06244237442606
Pubmed

Structure of Schlafen13 reveals a new class of tRNA/rRNA- targeting RNase engaged in translational control.

SLFN11 SLFN13

1.56e-06244229563550
Pubmed

Schlafen 11 triggers innate immune responses through its ribonuclease activity upon detection of single-stranded DNA.

SLFN11 SLFN13

4.69e-06344238875319
Pubmed

Interactomic analysis of REST/NRSF and implications of its functional links with the transcription suppressor TRIM28 during neuronal differentiation.

MOK RPL37A HNRNPU HNRNPM DDX54

6.10e-0620544527976729
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

NSD1 DNAH5 FER1L6 HNRNPM DDX54

1.16e-0523444536243803
Pubmed

Schlafen-8 is essential for lymphatic endothelial cell activation in experimental autoimmune encephalomyelitis.

SLFN11 SLFN13

1.56e-05544229528433
Pubmed

Subcellular localization of the Schlafen protein family.

SLFN11 SLFN13

1.56e-05544218355440
Pubmed

Expression and regulatory effects of murine Schlafen (Slfn) genes in malignant melanoma and renal cell carcinoma.

SLFN11 SLFN13

1.56e-05544224089532
Pubmed

Schlafen, a new family of growth regulatory genes that affect thymocyte development.

SLFN11 SLFN13

2.34e-0564429846487
Pubmed

The LIFEdb database in 2006.

NCOA7 SLFN11 SLFN13 PDZK1 SENP7 VDAC3 EPHA5

3.12e-0572044716381901
Pubmed

From ORFeome to biology: a functional genomics pipeline.

NCOA7 SLFN11 SLFN13 PDZK1 SENP7 VDAC3 EPHA5

3.17e-0572244715489336
Pubmed

Modulation of T cell development and activation by novel members of the Schlafen (slfn) gene family harbouring an RNA helicase-like motif.

SLFN11 SLFN13

3.27e-05744215351786
Pubmed

Evolution of the Schlafen genes, a gene family associated with embryonic lethality, meiotic drive, immune processes and orthopoxvirus virulence.

SLFN11 SLFN13

4.36e-05844219619625
Pubmed

DNA cloning using in vitro site-specific recombination.

NCOA7 SLFN11 SLFN13 PDZK1 SENP7 VDAC3 EPHA5

5.78e-0579444711076863
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

DNAJC9 SLFN11 TOP3A HNRNPU HNRNPM

6.89e-0534044524332808
Pubmed

Analysis of cDNA sequences from mouse testis.

SERINC3 BUB1

6.99e-05104428000140
Pubmed

Zbtb7b engages the long noncoding RNA Blnc1 to drive brown and beige fat development and thermogenesis.

HNRNPU HNRNPM

1.63e-041544228784777
Pubmed

FIP200 controls the TBK1 activation threshold at SQSTM1/p62-positive condensates.

SLFN11 RPL37A HNRNPU HNRNPM

1.83e-0422344434226595
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

NSD1 SLFN11 HNRNPM DDX54

2.82e-0425044433536335
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

PHLDB1 RPL37A HNRNPU SENP7 HNRNPM DDX54

3.02e-0473144629298432
Pubmed

USP10 regulates B cell response to SARS-CoV-2 or HIV-1 nanoparticle vaccines through deubiquitinating AID.

HNRNPU HNRNPM

4.24e-042444234983926
Pubmed

KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.

DNAJC9 RPL37A HNRNPU DDX54

4.39e-0428144426725010
Pubmed

Arginine methylation of SARS-Cov-2 nucleocapsid protein regulates RNA binding, its ability to suppress stress granule formation, and viral replication.

RPL37A HNRNPU DDX54

4.90e-0412144334029587
Pubmed

Shwachman-Bodian Diamond syndrome is a multi-functional protein implicated in cellular stress responses.

HNRNPU HNRNPM

5.38e-042744219602484
Pubmed

Perlecan regulates pericyte dynamics in the maintenance and repair of the blood-brain barrier.

ITGA4 ITGB8

5.38e-042744231541017
Pubmed

Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.

HNRNPU HNRNPM

5.79e-042844219596686
Pubmed

Upregulation of TIPE1 in tubular epithelial cell aggravates diabetic nephropathy by disrupting PHB2 mediated mitophagy.

HNRNPU HNRNPM

6.65e-043044235152003
Pubmed

Autophagy negatively regulates cancer cell proliferation via selectively targeting VPRBP.

HNRNPU HNRNPM

6.65e-043044222963397
Pubmed

A genetic approach to Mammalian glycan function.

NDST1 MGAT3

6.65e-043044212676797
Pubmed

Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer.

HNRNPU HNRNPM

6.65e-043044221575865
Pubmed

STING-Mediated IFI16 Degradation Negatively Controls Type I Interferon Production.

DTHD1 HNRNPU HNRNPM DDX54

6.82e-0431644431665637
Pubmed

Immunosuppressive lncRNA LINC00624 promotes tumor progression and therapy resistance through ADAR1 stabilization.

HNRNPU HNRNPM

7.57e-043244236252997
Pubmed

NFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cells.

HNRNPU HNRNPM

7.57e-043244217267499
Pubmed

The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.

RPL37A HNRNPU VDAC3 HNRNPM

8.01e-0433044432529326
Pubmed

Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2.

DNAJC9 HNRNPU VDAC3 DDX54

8.28e-0433344436779763
Pubmed

Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.

DNAJC9 HNRNPU VDAC3 HNRNPM

8.38e-0433444430425250
Pubmed

RBP2 is an MRG15 complex component and down-regulates intragenic histone H3 lysine 4 methylation.

HNRNPU HNRNPM

9.59e-043644217573780
Pubmed

Endogenous human MDM2-C is highly expressed in human cancers and functions as a p53-independent growth activator.

HNRNPU HNRNPM

9.59e-043644224147044
Pubmed

NLRP7 deubiquitination by USP10 promotes tumor progression and tumor-associated macrophage polarization in colorectal cancer.

RPL37A HNRNPU HNRNPM

1.01e-0315544333838681
Pubmed

Analysis of Ku70 S155 Phospho-Specific BioID2 Interactome Identifies Ku Association with TRIP12 in Response to DNA Damage.

NSD1 VDAC3 HNRNPM

1.02e-0315644337108203
Pubmed

Multiple myeloma-associated chromosomal translocation activates orphan snoRNA ACA11 to suppress oxidative stress.

HNRNPU HNRNPM DDX54

1.08e-0315944322751105
Pubmed

ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.

HNRNPU VDAC3 RPL37AP8 HNRNPM DDX54

1.11e-0362444533729478
Pubmed

Cellular RNA binding proteins NS1-BP and hnRNP K regulate influenza A virus RNA splicing.

HNRNPU HNRNPM

1.18e-034044223825951
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

CDK5RAP2 PHLDB1 SLFN11 FER1L6 VPS13A

1.23e-0363844531182584
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

RPL37A HNRNPU BUB1 HNRNPM DDX54

1.24e-0363944523443559
Pubmed

Characterization of the DOT1L network: implications of diverse roles for DOT1L.

HNRNPU HNRNPM

1.24e-034144220431927
GeneFamilySchlafen family

SLFN11 SLFN13

6.75e-0573321110
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAJC9 PRSS42P CDK5RAP2 BUB1

2.48e-05172444c06ca5d075937747952ed915c9db39a9f62072f9
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

SUGCT ITGB8 PDZK1 VPS13A

3.23e-0518444451ed1ebfdef45149541917c66cbacad87072e51f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOK DTHD1 DNAH5 KLKB1

3.30e-0518544405bc89a566b0db90ae06506e067190a4739a0974
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MOK DTHD1 DNAH5 SLFN13

3.30e-05185444f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCelldroplet-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD1 RPL37A ITGA4 HNRNPU

3.37e-0518644426f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCellCOVID-19-kidney-tDL|kidney / Disease (COVID-19 only), tissue and cell type

SUGCT ITGB8 PDZK1 VPS13A

3.44e-05187444d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCellpdx-Tumor_cells-T8|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NDST1 SUGCT FER1L6 PDZK1

3.67e-05190444b05db0de9b6ae01dd30074453f7de44f7397631e
ToppCellASK452-Epithelial-Ciliated|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

MOK DTHD1 DNAH5 SLFN13

3.90e-05193444c0d10075862ac878aa05fc49c8b73e470783bf16
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MOK DTHD1 DNAH5 SLFN13

3.98e-051944444a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK DTHD1 DNAH5 SLFN13

4.06e-051954443486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ITGA4 DTHD1 RAB37 SLFN13

4.14e-051964449bb87d20c25df0dc8e48bcb32b57f81a3dc1c0cd
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MOK DTHD1 DNAH5 SLFN13

4.30e-05198444ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DTHD1 SLFN13 HNRNPU VPS13A

4.39e-05199444f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Intermediate|6m / Sample Type, Dataset, Time_group, and Cell type.

KLHL41 RPL37A HNRNPU HNRNPM

4.48e-052004447c261e39ac30b318511373ab7302aa53b8b81b9c
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-like|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KLKB1 FER1L6 EPHA5

3.13e-0413444364979e1a056b7406e1be39c5ebe2f8d731ac3c17
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B0|356C / Donor, Lineage, Cell class and subclass (all cells)

DTHD1 KLKB1 SLFN13

3.34e-04137443fec21e7a25241289b18aea6a46dc2b981438ebe6
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-cortical_neurons_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

RPL37A EML6 SHB

3.71e-04142443435f39976841438690fcbf85bfa8e7f5b9e43916
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

PHLDB1 KLKB1 HNRNPU

3.86e-041444433ba7f8bd6d1c551048403c94693d63e60f7cbbb7
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PHLDB1 KLKB1 HNRNPU

3.86e-0414444338ff324366ad5be626e3657c1e33277fc36ddd4c
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

NDST1 PLK2 MYO1A

4.44e-04151443cba0939a6dd3519f6890695f5b237266ca1a7941
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

NDST1 PLK2 MYO1A

4.44e-04151443a937e3e5a63bfeb37d2cabb3177760ec583dbf11
ToppCell10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-B|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DTHD1 RAB37 SLFN13

4.61e-04153443d8773ee16c7d3e0834b9f64054d42336d6f9833b
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DTHD1 DNAH5 EML6

4.70e-0415444358072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DTHD1 DNAH5 EML6

4.70e-041544439ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellfacs-Brain_Myeloid-Cerebellum|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A ITGA4 RAB37

4.88e-0415644328c4fb4d2c6c47696c3a6722998f9da5a8923323
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA4 RAB37 SLFN13

4.97e-04157443d12f343454202da86a06d0369f8ffe5662cd091b
ToppCelldroplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLK2 RAB37 TOP3A

5.06e-041584431d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A ITGA4 RAB37

5.06e-04158443f41ee21e5888359d817be1e3a902c132cb68e350
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A ITGA4 RAB37

5.06e-04158443d689feb7f612aef170da76fcf14abf2dd589082b
ToppCellfacs-Brain_Myeloid-Cerebellum-24m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A ITGA4 RAB37

5.06e-04158443829ff3df46f173f2ff1c435e9bce35425e603b42
ToppCellTCGA-Mesothelium-Primary_Tumor-Mesothelioma-Biphasic-6|TCGA-Mesothelium / Sample_Type by Project: Shred V9

NDST1 TOP3A BUB1

5.16e-0415944385501c636cd04f15ba1be24df1ba7ac909633ce8
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAJC9 ITGA4 BUB1

5.25e-041604438e2b51d7b42e0b6e62641efdbbc73d31561d6a3e
ToppCell343B-Myeloid-Dendritic-cDC1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

NCOA7 RPL37A ZNF197

5.35e-04161443537a1d86de99a493b0345ca0f760994260e97049
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KLKB1 BUB1 EPHA5

5.45e-04162443bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMK+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ITGA4 KLKB1 ADAM20

5.45e-0416244319395bdb282b4a2d88cd33191af12c24a88c3d16
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

HOXA3 ITGB8 BUB1

5.64e-04164443fb18b863152fb3109e2224c791c84c6371680a4e
ToppCellfacs-Lung-EPCAM-3m-Endothelial-vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA7 NDST1 EML6

5.64e-041644431d0d88132baaa3154c3e6e4ef0aff795afab08a2
ToppCellfacs-Lung-EPCAM-3m-Endothelial-Vein_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA7 NDST1 EML6

5.64e-04164443bd2e10b015d5e6a338675500ec5d81dc39583b3e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SUGCT SLCO1B1 ITGB8

5.64e-04164443382e42701779d12a7948690b3be72d06dd75c8b4
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-Activated_T|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DTHD1 SLFN13 ADAM20

5.85e-04166443fb2cfbf1d0a0f1950dd24c08ba00ebd64b06ceb4
ToppCellfacs-Lung-Endomucin-24m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJC9 CDK5RAP2 RPL37A

5.95e-041674434520ee71e2b119c1dfa0e342fe57eda5f3598650
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAJC9 RAB37 BUB1

5.95e-04167443859dfe0764cb69de27e79e1c1aa65f9d538f79ea
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)|368C / Donor, Lineage, Cell class and subclass (all cells)

ITGB8 ZNF197 BUB1

6.05e-041684431bc6a1915d48f547385ed4f44e118bcc8a4a7b6c
ToppCell368C-Fibroblasts-Fibroblast-C_(Myofibroblast)-|368C / Donor, Lineage, Cell class and subclass (all cells)

ITGB8 ZNF197 BUB1

6.05e-0416844369f534de0f9a293047bea03cb1b78551087a8df5
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

HOXA3 ITGB8 PDZK1

6.05e-04168443a086c306be430adf0632ba53e98cd8014d2de330
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MOK DTHD1 DNAH5

6.16e-0416944314aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellcontrol-Epithelial-Ciliated-diff|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MYO1A DTHD1 DNAH5

6.26e-04170443334c4103eb6e021766f5638a4ab14b59ad085ac7
ToppCellfacs-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCOA7 ADCY6 ITGB8

6.26e-04170443df1a34a69ae404c56f00751a01f52359535f5469
ToppCellcontrol-Myeloid-Eosinophils|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAT3 ITGB8 SHB

6.37e-0417144382f736c33ed96c0865618e8f8eb82a5487126bdc
ToppCellmild-Myeloid-Eosinophils|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MGAT3 SLFN13 ITGB8

6.37e-041714435c8198182495bda7a826e9d80aa467f4eb1094ec
ToppCellNS-critical-LOC-Lymphoid-NK|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ITGA4 SLFN13 VPS13A

6.37e-04171443adda76991d9b150bb8ccf3989b7cbbf41843cf0b
ToppCell3'_v3-blood-Mast|blood / Manually curated celltypes from each tissue

HOXA3 RAB37 ITGB8

6.48e-04172443e7a46bbeff749ca59b9f1357409ce1ad59dd22dd
ToppCellP15-Mesenchymal-developing_mesenchymal_cell-mesenchymal_proliferating_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DNAJC9 TOP3A BUB1

6.48e-041724437c238a7375341d4647ba7274d93fddfb6fae7ce4
ToppCellChildren_(3_yrs)-Epithelial-lung_goblet_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

KLHL41 DNAH5 FER1L6

6.59e-04173443464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SUGCT BUB1 EML6

6.59e-04173443b7e0193fd4983cb38d1bee441f608f73ee8743b9
ToppCell10x5'-blood-Mast-Mast_cells|blood / Manually curated celltypes from each tissue

MGAT3 RAB37 ITGB8

6.70e-04174443a5838821bba2be790d32331ff529d466e9974268
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA4 DTHD1 RAB37

6.70e-0417444347e308a777c927ae69ed344cb3dd8561bf2c48a5
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CDK5RAP2 BUB1 EML6

6.70e-041744436c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCell10x5'-blood-Mast|blood / Manually curated celltypes from each tissue

MGAT3 RAB37 ITGB8

6.70e-041744433a8a253213b207e3ff56f94a74996b8d9ad47aa1
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-D_cells_(SST+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAB37 CNGA3 PDZK1

6.70e-04174443019eae059bd9eb107dee8f0d0f574ca36c2c26e1
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGA4 DTHD1 RAB37

6.70e-04174443a92c745d20633909db0f08effa13fc738fda79a6
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-regulatory_T_cell-regulatory_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DTHD1 RAB37 ITGB8

6.81e-041754433bdccb4037053795d62ab5b6fcc09cdd406f9b50
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ITGB8 PDZK1 EML6

6.81e-04175443284fdc7a9d303636a637041846850d19d114861a
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAJC9 PRSS42P BUB1

6.81e-04175443a154b28b0b2180652d51d4c7d804b3b81b35899e
ToppCelldroplet-Lung-30m-Hematologic-lymphocytic-regulatory_T_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DTHD1 RAB37 ITGB8

6.81e-04175443770546ddaa49ee482c4c7577ab76efbc6c304a29
ToppCellfacs-GAT-Fat-3m-Lymphocytic|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A ITGA4 RAB37

6.93e-041764432e3f25a338842384517656d05776a52cbfc62b52
ToppCell3'_v3-blood-Mast-Mast_cells|blood / Manually curated celltypes from each tissue

HOXA3 RAB37 ITGB8

6.93e-04176443b9da3deaf62622d47eb30b6be7548253eee95597
ToppCellfacs-GAT-Fat-3m-Lymphocytic-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A ITGA4 RAB37

6.93e-041764430823088bc6b19c7ad784d83c2ccdfae80611afab
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DNAJC9 ITGA4 BUB1

6.93e-041764436b1cf1e98b4509e87f9eea827fa7090ce1e504f1
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DNAJC9 ITGA4 BUB1

6.93e-041764439e719e6323597ecfc758c957256872cd4ae24d4d
ToppCellfacs-Lung-EPCAM-3m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA7 ADCY6 ITGB8

7.04e-04177443d445167dae956e641386f84ab3ae9f47c089e09a
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOK DNAH5 KLKB1

7.16e-04178443f02076ece0fa899e620971c887ad4da7f48684ed
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCOA7 ADCY6 ITGB8

7.16e-041784430b456ac768e026c3ecd5a9a4f43d6f126e7685a1
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOK DNAH5 KLKB1

7.16e-041784436178706db4a855d72abc156537604d575624df56
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK5RAP2 RAB37 ITGB8

7.27e-04179443b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ITGA4 RAB37 ITGB8

7.27e-04179443810972561d1ae5a68389b54ceeac7a49890513a4
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAT3 RAB37 ITGB8

7.27e-04179443e880c507f11ce75d104593a4ca29f0295f8125e8
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-T_cells-NK_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ITGA4 DTHD1 SLFN13

7.39e-04180443512c005567ad9c78cc5cc83862fc1219bcf49f60
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MOK ITGB8 EML6

7.39e-041804431e819c5c87704ec6535dfeaae56561895e239d07
ToppCellCOVID-19-kidney-tDL|COVID-19 / Disease (COVID-19 only), tissue and cell type

SUGCT ITGB8 PDZK1

7.39e-04180443864c895b5eaedefae86f5829fa344f7b686fb59f
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SUGCT ITGB8 PDZK1

7.39e-04180443358923e4228035a3e90e2957392089219e90dcd7
ToppCelldroplet-Heart-nan-24m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MGAT3 RAB37 ADCY6

7.39e-0418044378fdcfb3fdbf36469cae78407cda5bd0996930d8
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDK5RAP2 KLHL41 BUB1

7.39e-0418044343fd5c498a87bb078d101298b472656f3294686a
ToppCellfacs-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERINC3 RPL37A HNRNPU

7.39e-0418044387fb1fdbc49c808bb5f6fe9fb747057b45fa78d0
ToppCellCOVID-19-kidney-NK|COVID-19 / Disease (COVID-19 only), tissue and cell type

ITGA4 DTHD1 SLFN13

7.51e-041814438906ee8a7a1616dfe8c3b5c73988416641213629
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNGA3 ITGB8 EPHA5

7.51e-04181443cb17c904ab86d56dd30cac9b61acbb3b76f84ded
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SUGCT ITGB8 PDZK1

7.51e-041814436956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MOK DTHD1 DNAH5

7.51e-04181443dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-NK_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DTHD1 RAB37 SLFN13

7.63e-04182443feda21c92d30848de70c8b404eaabbca3f5e894d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SUGCT ITGB8 PDZK1

7.63e-041824435e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCelldroplet-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL37A ITGA4 HNRNPU

7.63e-04182443eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD1 PLK2 ITGA4

7.63e-04182443f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCellCOVID-19-kidney-Distal_Epi_Doublet_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

SUGCT ITGB8 PDZK1

7.63e-041824439d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCelldroplet-Lung-LUNG-30m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOK MGAT3 DNAH5

7.75e-041834433991830726d05cf19606d540de04093985b7bdeb
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-Ependyma|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTHD1 DNAH5 KLKB1

7.75e-0418344318040d0653286071df959513c63d94b555a5d00a
ToppCellCOVID-19-kidney-PCT-S1|COVID-19 / Disease (COVID-19 only), tissue and cell type

SUGCT ITGB8 PDZK1

7.75e-041834436878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMK+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

NCOA7 ITGA4 DTHD1

7.75e-0418344379defd22b3194dad16db55b9bdd220c09c1e6b90
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CDK5RAP2 KLHL41 BUB1

7.75e-04183443e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCelldroplet-Lung-LUNG-30m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MOK MGAT3 DNAH5

7.75e-04183443cc844f54c7564bf432b179ca63bc7c4b9b8cfdd9
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Mesenchymal-ependymal_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DTHD1 DNAH5 KLKB1

7.75e-041834436ca7c2d7c56e0f1b9038ba677b4c1c3dfd63bfce
ComputationalNeighborhood of RRM1

DNAJC9 HNRNPU BUB1 HNRNPM

1.51e-04102294MORF_RRM1
ComputationalNeighborhood of DNMT1

DNAJC9 HNRNPU VDAC3 HNRNPM

2.65e-04118294MORF_DNMT1
ComputationalNeighborhood of RFC4

DNAJC9 HNRNPU BUB1 VDAC3

6.76e-04151294MORF_RFC4
ComputationalNeighborhood of BUB3

DNAJC9 HNRNPU BUB1 VDAC3 HNRNPM

7.84e-04277295MORF_BUB3
ComputationalNeighborhood of HDAC2

DNAJC9 HNRNPU BUB1 VDAC3 HNRNPM

8.23e-04280295MORF_HDAC2
ComputationalNeighborhood of PPP1CC

DNAJC9 HNRNPU BUB1 VDAC3

9.64e-04166294MORF_PPP1CC
ComputationalNeighborhood of HAT1

DNAJC9 HNRNPU BUB1 HNRNPM

1.17e-03175294MORF_HAT1
DrugFenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; MCF7; HT_HG-U133A

NDST1 PHLDB1 ITGA4 ADAM20 ITGB8 BUB1

2.15e-061984466001_UP
Diseasemicrocephaly (is_implicated_in)

NSD1 CDK5RAP2

6.05e-058442DOID:10907 (is_implicated_in)
DiseaseDiGeorge syndrome (implicated_via_orthology)

HOXA3 NDST1

3.66e-0419442DOID:11198 (implicated_via_orthology)
Diseasereticulocyte count

NCOA7 PLK2 MGAT3 ITGA4 SLCO1B1 EML6 VPS13A

8.35e-041045447EFO_0007986
Diseasemean arterial pressure

HOXA3 PRSS42P PLK2 TOP3A EML6

8.55e-04499445EFO_0006340
DiseaseInflammatory Bowel Diseases

ITGA4 ITGB8

1.25e-0335442C0021390
DiseaseX-12063 measurement

SUGCT SLCO1B1 DNAH5

2.70e-03186443EFO_0021283

Protein segments in the cluster

PeptideGeneStartEntry
GAIMAGLIQKYKTGK

SUGCT

221

Q9HAC7
GYGFGMVKIDLKTKS

VDAC3

21

Q9Y277
GTYMKVKNEGGECKP

BUB1

1001

O43683
KDTQGMKLGVAYVKG

ADAM20

301

O43506
RGVVKVKGKGEMTTY

ADCY6

1146

O43306
IGKCMCKAGYEEKNG

EPHA5

286

P54756
LVKLCSGMVEAGKAY

ACAP3

36

Q96P50
MKDLSKGGCKNGYLR

CDK5RAP2

736

Q96SN8
SSKDKMGKGVDGTYK

NSD1

1821

Q96L73
MGKGVDGTYKKALQE

NSD1

1826

Q96L73
KVMLLGDTGVGKTCF

RAB37

31

Q96AX2
GFSLKTVQGKKGVYM

PDZK1

146

Q5T2W1
YKKDQKGKGMLTSSG

HOXA3

246

O43365
TKAGGVCFKPGTKML

MGAT3

111

Q09327
SKLVMSYVAAVCGKG

MYO1A

111

Q9UBC5
YADIKMENGKSKGCG

HNRNPM

681

P52272
KKKKSGGFQSMGLSY

DDX54

91

Q8TDD1
SYGVSKGKVCFEMKV

HNRNPU

326

Q00839
TKCLGKSKGRKYPEM

NDST1

826

P52848
KGMIYCLGGKTDDKK

KLHL41

446

O60662
MKNYKAIGKIGEGTF

MOK

1

Q9UQ07
MAKRTKKVGIVGKYG

RPL37A

1

P61513
MKKCDVTGGKNYAII

ITGB8

436

P26012
MKGGYKGTCASVKVY

DTHD1

276

Q6ZMT9
AQMEAKYCKSSKGGG

DNAJC9

236

Q8WXX5
EMKGKKLGSYFGASV

ITGA4

296

P13612
KITQRMVCAGYKEGG

KLKB1

556

P03952
LYKKGVIGSLGAAKM

EML6

1541

Q6ZMW3
MGGYTGKVCVRAKVL

SLFN13

501

Q68D06
KTETTKDMGRCLGKY

DNAH5

1986

Q8TE73
TKGYLKCDISVMGKG

FER1L6

196

Q2WGJ9
SVYIGKIKGASKGCV

SENP7

526

Q9BQF6
LKSKAGKGESAGYME

SHB

256

Q15464
TGGGMHKKDTLKECL

NCOA7

426

Q8NI08
MAKCTKKVGGIVSKY

RPL37AP8

1

A6NKH3
MGGYTGKVCVRAKVL

SLFN11

501

Q7Z7L1
EIVGKGCLKESGSYM

SLCO1B1

156

Q9Y6L6
GDYICKKGDIGKEMY

CNGA3

506

Q16281
LIGTEGKKFYKCDMC

ZNF197

361

O14709
TVGSHGAVKCKGLKM

VPS13A

2276

Q96RL7
GAVKCKGLKMDYQVG

VPS13A

2281

Q96RL7
VIIKGMVCGYKEQGK

PRSS42P

246

Q7Z5A4
SKVCRGYLVKMGGKI

PHLDB1

1256

Q86UU1
METYLKKIPGFCEGG

SERINC3

61

Q13530
VLKTKKNGGFYLSCM

TOP3A

666

Q13472
KVLGKGGFAKCYEMT

PLK2

86

Q9NYY3