Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DYNC2H1 DNAH1 DNAH8 DNAH9

1.35e-05181684GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DYNC2H1 DNAH1 DNAH8 DNAH9

8.45e-05281684GO:0051959
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC3 DYNC2H1 KIF16B PEX1 SRP54 CHD1 SMARCAD1 ABCE1 NAV1 DDX60L DNAH8 DNAH9 DDX4

9.53e-0544116813GO:0016887
GeneOntologyMolecularFunctiondynein intermediate chain binding

DYNC2H1 DNAH1 DNAH8 DNAH9

2.57e-04371684GO:0045505
GeneOntologyMolecularFunctionmicrotubule motor activity

DYNC2H1 KIF16B DNAH1 DNAH8 DNAH9

3.09e-04701685GO:0003777
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH1 DNAH8 DNAH9

5.10e-06141624IPR024317
DomainDynein_HC_stalk

DYNC2H1 DNAH1 DNAH8 DNAH9

5.10e-06141624IPR024743
DomainDynein_heavy_dom-2

DYNC2H1 DNAH1 DNAH8 DNAH9

5.10e-06141624IPR013602
DomainDHC_N2

DYNC2H1 DNAH1 DNAH8 DNAH9

5.10e-06141624PF08393
DomainATPase_dyneun-rel_AAA

DYNC2H1 DNAH1 DNAH8 DNAH9

5.10e-06141624IPR011704
DomainMT

DYNC2H1 DNAH1 DNAH8 DNAH9

5.10e-06141624PF12777
DomainAAA_8

DYNC2H1 DNAH1 DNAH8 DNAH9

5.10e-06141624PF12780
DomainAAA_5

DYNC2H1 DNAH1 DNAH8 DNAH9

5.10e-06141624PF07728
DomainDHC_fam

DYNC2H1 DNAH1 DNAH8 DNAH9

6.91e-06151624IPR026983
DomainDynein_heavy

DYNC2H1 DNAH1 DNAH8 DNAH9

6.91e-06151624PF03028
DomainDynein_heavy_dom

DYNC2H1 DNAH1 DNAH8 DNAH9

6.91e-06151624IPR004273
DomainVinculin/catenin

TLN1 CTNNA3 TLN2

2.19e-0571623IPR006077
DomainDHC_N1

DYNC2H1 DNAH8 DNAH9

3.47e-0581623PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DNAH8 DNAH9

3.47e-0581623IPR013594
DomainAAA

ABCC3 DYNC2H1 PEX1 SRP54 ABCE1 NAV1 DNAH8 DNAH9

3.74e-051441628SM00382
DomainAAA+_ATPase

ABCC3 DYNC2H1 PEX1 SRP54 ABCE1 NAV1 DNAH8 DNAH9

3.74e-051441628IPR003593
Domain-

TLN1 TLN2

7.48e-05216221.20.1420.10
DomainSMK-1

PPP4R3A PPP4R3B

7.48e-0521622PF04802
DomainVBS

TLN1 TLN2

7.48e-0521622PF08913
DomainVinculin-bd_dom

TLN1 TLN2

7.48e-0521622IPR015009
DomainTalin_cent

TLN1 TLN2

7.48e-0521622IPR015224
DomainTalin_middle

TLN1 TLN2

7.48e-0521622PF09141
DomainDUF625

PPP4R3A PPP4R3B

7.48e-0521622IPR006887
Domain-

ABCC3 DLG5 DYNC2H1 PEX1 SRP54 CHD1 SMARCAD1 DNAH1 CASK ARHGAP5 ABCE1 ERAL1 GNL2 NAV1 DDX60L DNAH8 DNAH9 DDX4

8.64e-05746162183.40.50.300
DomainP-loop_NTPase

ABCC3 DLG5 DYNC2H1 KIF16B PEX1 SRP54 CHD1 SMARCAD1 DNAH1 CASK ARHGAP5 ABCE1 ERAL1 GNL2 NAV1 DDX60L DNAH8 DNAH9 DDX4

1.44e-0484816219IPR027417
DomainCREPT

RPRD1B RPRD1A

2.23e-0431622IPR032337
DomainCREPT

RPRD1B RPRD1A

2.23e-0431622PF16566
DomainTalin-1

TLN1 TLN2

2.23e-0431622IPR015710
DomainILWEQ_dom

TLN1 TLN2

4.44e-0441622IPR002558
DomainPXA

SNX13 SNX25

4.44e-0441622SM00313
DomainILWEQ

TLN1 TLN2

4.44e-0441622SM00307
DomainFERM_f0

TLN1 TLN2

4.44e-0441622PF16511
DomainILWEQ

TLN1 TLN2

4.44e-0441622PD011820
DomainPXA

SNX13 SNX25

4.44e-0441622PS51207
DomainPXA

SNX13 SNX25

4.44e-0441622PF02194
Domain-

TLN1 TLN2

4.44e-04416221.20.1410.10
DomainI_LWEQ

TLN1 TLN2

4.44e-0441622PF01608
DomainI_LWEQ

TLN1 TLN2

4.44e-0441622PS50945
DomainSorting_nexin_C

SNX13 SNX25

4.44e-0441622IPR013937
DomainFERM_f0

TLN1 TLN2

4.44e-0441622IPR032425
DomainPhox_assoc

SNX13 SNX25

4.44e-0441622IPR003114
DomainNexin_C

SNX13 SNX25

4.44e-0441622PF08628
DomainCreatin/AminoP/Spt16_NTD

XPNPEP1 SUPT16H

7.35e-0451622IPR029149
Domain-

XPNPEP1 SUPT16H

7.35e-04516223.40.350.10
DomainTPR_2

TMTC2 TTC8 FKBP4 NAA16

9.21e-04501624PF07719
DomainTPR_2

TMTC2 TTC8 FKBP4 NAA16

9.21e-04501624IPR013105
DomainBromodomain_CS

BAZ2B BRDT EP300

1.44e-03261623IPR018359
DomainRNA_pol_II-bd

RPRD1B RPRD1A

1.53e-0371622IPR006903
DomainCTD_bind

RPRD1B RPRD1A

1.53e-0371622PF04818
DomainRPR

RPRD1B RPRD1A

2.02e-0381622SM00582
DomainCID_dom

RPRD1B RPRD1A

2.02e-0381622IPR006569
DomainCID

RPRD1B RPRD1A

2.02e-0381622PS51391
DomainPept_M24

XPNPEP1 SUPT16H

2.59e-0391622IPR000994
DomainPeptidase_M24

XPNPEP1 SUPT16H

2.59e-0391622PF00557
Domain-

XPNPEP1 SUPT16H

2.59e-03916223.90.230.10
Domainfn3

PRTG TNC PTPRD PTPRF PTPRS ROS1

2.92e-031621626PF00041
DomainRGS

SNX13 GRK1 SNX25

3.42e-03351623PF00615
DomainRGS

SNX13 GRK1 SNX25

3.42e-03351623SM00315
DomainRGS

SNX13 GRK1 SNX25

3.71e-03361623PS50132
DomainPTPc

PTPRD PTPRF PTPRS

3.71e-03361623SM00194
DomainTyr_Pase_AS

PTPRD PTPRF SSH1 PTPRS

3.73e-03731624IPR016130
Domain-

INTS14 CLCA2 ANTXR1 VWA3B

3.92e-037416243.40.50.410
DomainBROMODOMAIN_1

BAZ2B BRDT EP300

4.01e-03371623PS00633
DomainBromodomain

BAZ2B BRDT EP300

4.33e-03381623PF00439
DomainRGS

SNX13 GRK1 SNX25

4.66e-03391623IPR016137
DomainTYR_PHOSPHATASE_PTP

PTPRD PTPRF PTPRS

4.66e-03391623PS50055
DomainPTPase_domain

PTPRD PTPRF PTPRS

5.36e-03411623IPR000242
DomainY_phosphatase

PTPRD PTPRF PTPRS

5.36e-03411623PF00102
DomainBROMODOMAIN_2

BAZ2B BRDT EP300

5.36e-03411623PS50014
DomainWH1

PPP4R3A PPP4R3B

5.48e-03131622PS50229
DomainFN3

PRTG TNC PTPRD PTPRF PTPRS ROS1

5.57e-031851626SM00060
DomainVWFA

INTS14 CLCA2 ANTXR1 VWA3B

5.65e-03821624PS50234
DomainBromodomain

BAZ2B BRDT EP300

5.74e-03421623IPR001487
DomainBROMO

BAZ2B BRDT EP300

5.74e-03421623SM00297
Domain-

BAZ2B BRDT EP300

5.74e-034216231.20.920.10
DomainVWA

INTS14 CLCA2 ANTXR1 VWA3B

6.15e-03841624SM00327
DomainIg_I-set

PRTG ROR1 PTPRD PTPRF PTPRS ALPK2

6.33e-031901626IPR013098
DomainI-set

PRTG ROR1 PTPRD PTPRF PTPRS ALPK2

6.33e-031901626PF07679
DomainIRS

TLN1 TLN2

6.35e-03141622PF02174
DomainIRS_PTB

TLN1 TLN2

6.35e-03141622IPR002404
DomainPX

KIF16B SNX13 SNX25

6.54e-03441623SM00312
DomainTYR_PHOSPHATASE_1

PTPRD PTPRF SSH1 PTPRS

6.67e-03861624PS00383
DomainTYR_PHOSPHATASE_dom

PTPRD PTPRF SSH1 PTPRS

6.95e-03871624IPR000387
DomainTYR_PHOSPHATASE_2

PTPRD PTPRF SSH1 PTPRS

6.95e-03871624PS50056
DomainTPR_1

TMTC2 TTC8 FKBP4 NAA16

7.82e-03901624IPR001440
DomainTPR_1

TMTC2 TTC8 FKBP4 NAA16

7.82e-03901624PF00515
DomainFN3

PRTG TNC PTPRD PTPRF PTPRS ROS1

7.87e-031991626PS50853
Domain-

PTPRD PTPRF SSH1 PTPRS

8.44e-039216243.90.190.10
DomainIg-like_fold

PRTG TNC ROR1 CAMTA2 SEMA3A TRIM45 PTPRD PTPRF NFATC2 PTPRS CD274 ROS1 ALPK2

8.64e-0370616213IPR013783
Pubmed

Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.

SEMA3A PTPRD PTPRF PTPRS

3.80e-088170428637841
Pubmed

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.

PTPRD PTPRF PTPRS

1.15e-073170331985401
Pubmed

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

PTPRD PTPRF PTPRS

1.15e-073170320139422
Pubmed

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.

PTPRD PTPRF PTPRS

1.15e-073170333656439
Pubmed

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.

PTPRD PTPRF PTPRS

1.15e-07317039784606
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

RBM15 SET POLR2G THUMPD1 SRP54 CHD1 SMARCAD1 PPP4R3A RPRD1B PPP4R3B RBM27 ABCE1 ARIH2 SUPT16H MKI67 TOP1 CWF19L1 FKBP4 EP300 ZNF687

1.38e-0710141702032416067
Pubmed

Ubiquitin-Independent Disassembly by a p97 AAA-ATPase Complex Drives PP1 Holoenzyme Formation.

RPL28 RBM15 RAE1 AHCTF1 RPS11 RBM28 RPRD1B CASK KIAA1217 SUPT16H MKI67 NAV1

2.46e-073611701230344098
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

AHCTF1 KIF16B PEX1 THUMPD1 RANBP6 SRP54 RBM28 ARMCX4 CASK CLPTM1L IBTK ABCE1 ERAL1 AASS TMLHE KIAA1217 PANK4 SUPT16H GNL2 NAV1 SENP2 TOP1 FKBP4 DDX4

3.21e-0714961702432877691
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

RPL28 RBM15 FYTTD1 RAE1 BAZ2B AHCTF1 RPS11 SAP30L RBM28 MBIP TFE3 RPRD1B NGDN RMI1 INTS14 INTS2 RBM27 SUPT16H MKI67 TOP1 EP300 ZNF687

3.98e-0712941702230804502
Pubmed

The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

PTPRD PTPRF PTPRS

4.57e-07417038524829
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

BAZ2B AHCTF1 POLR2G RPS11 CHD1 RPRD1B NGDN SUV39H1 SUPT16H MKI67 TOP1

1.03e-063401701129478914
Pubmed

Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs.

PTPRD PTPRF PTPRS

1.14e-065170310777529
Pubmed

Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.

PTPRD PTPRF PTPRS

1.14e-065170322357843
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

RPL28 DLG5 RBM15 RAE1 DYNC2H1 SMARCAD1 NR3C1 PPP4R3A CDC7 PPP4R3B RMI1 BRCA2 KIAA1217 NAV1

1.33e-065881701438580884
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

FYTTD1 RAE1 DYNC2H1 POLR2G RPRD1B CASK SEMA3A RPRD1A SUPT16H MKI67 EP300

1.70e-063581701132460013
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

RAE1 POLR2G RBM28 PPP4R3A RPRD1B PPP4R3B RPRD1A RBM27 SUPT16H MKI67 GNL2 ZNF687

1.96e-064401701234244565
Pubmed

Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases.

PTPRD PTPRF PTPRS

2.27e-066170319273906
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

RPL28 SET RPS11 THUMPD1 RANBP6 FRYL SMARCAD1 XPNPEP1 NR3C1 PPP4R3A RPRD1B PPP4R3B RPRD1A APPL2 SETSIP ABCE1 TLN1 ARIH2 PANK4 SUPT16H FKBP4 DNPEP

2.73e-0614551702222863883
Pubmed

SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis.

TNC TLN1 MKI67 TLN2

3.09e-0621170432591430
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

VIL1 DLG5 RBM15 FYTTD1 RAE1 AHCTF1 PEG3 SRP54 RBM28 NGDN ESCO2 ARHGAP5 IBTK RBM27 ERAL1 TLN1 SUPT16H MKI67 GNL2 ROS1 TOP1

3.85e-0613711702136244648
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

RPL28 DLG5 DYNC2H1 AHCTF1 KIF16B SRP54 CHD1 SMARCAD1 RBM28 NR3C1 CASK CDC42EP1 CLPTM1L SACS ERAL1 TLN1 PANK4 SUPT16H GNL2 SENP2 PLCH1 FKBP4

3.87e-0614871702233957083
Pubmed

Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.

PTPRD PTPRF PTPRS

3.96e-067170312376545
Pubmed

Modulation of apoptotic response by LAR family phosphatases-cIAP1 signaling during urinary tract morphogenesis.

PTPRD PTPRF PTPRS

3.96e-067170329073098
Pubmed

Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development.

TLN1 MKI67 TLN2

3.96e-067170328993400
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RPL28 RBM15 SET RAE1 AHCTF1 RPS11 CHD1 RBM28 NGDN ARHGAP5 CLPTM1L RBM27 MKI67 GNL2 TOP1 ZNF687

4.58e-068471701635850772
Pubmed

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.

PTPRD PTPRF PTPRS

6.31e-068170337591863
Pubmed

Transcription factor protein interactomes reveal genetic determinants in heart disease.

RBM15 FYTTD1 RAE1 BAZ2B AHCTF1 RPS11 CHD1 ESCO2 INTS14 TOP1 EP300

6.33e-064111701135182466
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

SET FYTTD1 AHCTF1 PEG3 PEX1 SRP54 FRYL CAMTA2 RBM28 SPATA1 RPRD1B ESCO2 TBCCD1 ARHGAP5 INTS14 INTS2 ABCE1 ERAL1

6.73e-0610841701811544199
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RPL28 RBM15 SET DYNC2H1 RPS11 CHD1 SMARCAD1 RPRD1B CLPTM1L RPRD1A CLCA2 ABCE1 ERAL1 TLN1 SUPT16H MKI67 GNL2 TLN2 TOP1 FKBP4 DNPEP

6.95e-0614251702130948266
Pubmed

Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform.

ROR1 PTPRD PTPRF PTPRS

7.57e-0626170436178190
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

RBM15 SET RAE1 HEBP2 BAZ2B KCNAB2 SRP54 RBM28 PPP4R3A PPP4R3B RBM27 ABCE1 TLN1 MKI67 TOP1 FKBP4 EP300 ZNF687

8.51e-0611031701834189442
Pubmed

Smek promotes corticogenesis through regulating Mbd3's stability and Mbd3/NuRD complex recruitment to genes associated with neurogenesis.

PPP4R3A PPP4R3B MKI67

9.43e-069170328467410
Pubmed

Nine loci for ocular axial length identified through genome-wide association studies, including shared loci with refractive error.

CACNA1D COL8A1 SET GNL2 ARHGAP18

9.77e-0658170524144296
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

OR8H2 SET RAE1 AHCTF1 SAP30L PEX1 SMARCAD1 ZNF518A CDC42EP1 INTS14 BRDT SETSIP PANK4 SUPT16H GNL2 TOP1 EP300 ZNF687

9.97e-0611161701831753913
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

GRIK4 TFE3 SLC3A1 MSGN1 PTPRD NFATC2 KIAA1217 CA6

1.05e-05212170819521566
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

DNAH1 PPP4R3B IBTK SSH1 RBM27 SENP2 ZNF687

1.10e-05153170710718198
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

RBM15 BAZ2B CHD1 ZNF518A CDC7 BRCA2 SUPT16H ZNF687

1.47e-05222170837071664
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RPL28 AHCTF1 RPS11 SRP54 CHD1 NR3C1 PPP4R3A IBTK RBM27 ABCE1 KIAA1217 TLN1 MKI67 GNL2 TOP1 FKBP4

1.54e-059341701633916271
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ABCC3 DYNC2H1 TNC KIF16B NR3C1 TFE3 RPRD1B NGDN CLPTM1L ABCE1 AASS EP300 ZNF687

1.69e-056381701331182584
Pubmed

PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission.

PTPRD PTPRF PTPRS

1.84e-0511170325624497
Pubmed

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

PTPRD PTPRF PTPRS

1.84e-051117037832766
Pubmed

TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease.

RAE1 MYLK2 MEIOC SNX25 MKI67

1.99e-0567170534644545
Pubmed

Loss of SMEK, a novel, conserved protein, suppresses MEK1 null cell polarity, chemotaxis, and gene expression defects.

PPP4R3A PPP4R3B

2.38e-052170216107728
Pubmed

Ep300 sequestration to functionally distinct glucocorticoid receptor binding loci underlie rapid gene activation and repression.

NR3C1 EP300

2.38e-052170235713523
Pubmed

Clinical significance and interrelations of PD-L1 expression, Ki-67 index, and molecular alterations in sporadic medullary thyroid carcinoma from a Chinese population.

MKI67 CD274

2.38e-052170235920918
Pubmed

The mouse gene Ptprf encoding the leukocyte common antigen-related molecule LAR: cloning, characterization, and chromosomal localization.

PTPRD PTPRF

2.38e-05217027665159
Pubmed

Adaptor Protein APPL2 Affects Adult Antidepressant Behaviors and Hippocampal Neurogenesis via Regulating the Sensitivity of Glucocorticoid Receptor.

NR3C1 APPL2

2.38e-052170228965332
Pubmed

Targeted ablation reveals a novel role of FKBP52 in gene-specific regulation of glucocorticoid receptor transcriptional activity.

NR3C1 FKBP4

2.38e-052170219073255
Pubmed

Overexpression, characterization, and purification of a recombinant mouse immunophilin FKBP-52 and identification of an associated phosphoprotein.

NR3C1 FKBP4

2.38e-05217028341706
Pubmed

Both Talin-1 and Talin-2 correlate with malignancy potential of the human hepatocellular carcinoma MHCC-97 L cell.

TLN1 TLN2

2.38e-052170226822056
Pubmed

Extracellular rigidity sensing by talin isoform-specific mechanical linkages.

TLN1 TLN2

2.38e-052170226523364
Pubmed

Detection in situ of genomic regulatory elements in Drosophila.

SMARCAD1 KIAA1217

2.38e-05217022827169
Pubmed

TFE3-PD-L1 axis is pivotal for sunitinib resistance in clear cell renal cell carcinoma.

TFE3 CD274

2.38e-052170233145941
Pubmed

The Glucocorticoid Receptor Regulates the ANGPTL4 Gene in a CTCF-Mediated Chromatin Context in Human Hepatic Cells.

NR3C1 ANGPTL4

2.38e-052170228056052
Pubmed

Restricted heterochromatin formation links NFATc2 repressor activity with growth promotion in pancreatic cancer.

NFATC2 SUV39H1

2.38e-052170222079596
Pubmed

3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex.

NR3C1 FKBP4

2.38e-052170215159550
Pubmed

Evidence that the peptidylprolyl isomerase domain of the hsp90-binding immunophilin FKBP52 is involved in both dynein interaction and glucocorticoid receptor movement to the nucleus.

NR3C1 FKBP4

2.38e-052170211278753
Pubmed

Enhancer trap integrations in mouse embryonic stem cells give rise to staining patterns in chimaeric embryos with a high frequency and detect endogenous genes.

SMARCAD1 KIAA1217

2.38e-05217021283314
Pubmed

New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.

TLN1 TLN2

2.38e-052170222306379
Pubmed

The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma.

PTPRD PTPRS

2.38e-05217029566880
Pubmed

Aberrant O-glycosylation contributes to tumorigenesis in human colorectal cancer.

TNC MUC2

2.38e-052170229999571
Pubmed

Angiopoietin-like 4 (ANGPTL4, fasting-induced adipose factor) is a direct glucocorticoid receptor target and participates in glucocorticoid-regulated triglyceride metabolism.

NR3C1 ANGPTL4

2.38e-052170219628874
Pubmed

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PTPRD PTPRF PTPRS

2.44e-051217039624153
Pubmed

Smek1/2 is a nuclear chaperone and cofactor for cleaved Wnt receptor Ryk, regulating cortical neurogenesis.

PPP4R3A PPP4R3B MKI67

2.44e-0512170329180410
Pubmed

UIF, a New mRNA export adaptor that works together with REF/ALY, requires FACT for recruitment to mRNA.

SET FYTTD1 SUPT16H

3.17e-0513170319836239
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DYNC2H1 DNAH1 DNAH8

4.01e-051417039373155
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

RBM15 RAE1 AHCTF1 RBM28 NGDN SUPT16H MKI67 GNL2 DDX60L

4.06e-05332170925693804
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

TNC HEATR4 ROR1 LCA5L GRIK4 SLC3A1 SSH1 KIAA1217 ERRFI1 DNAH8

4.53e-054201701028065597
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

RAE1 CHD1 SMARCAD1 RBM28 SUPT16H MKI67 GNL2 TOP1 ZNF687

4.99e-05341170932971831
Pubmed

Talin 1 and 2 are required for myoblast fusion, sarcomere assembly and the maintenance of myotendinous junctions.

TNC TLN1 TLN2

5.00e-0515170319793892
Pubmed

The sperm-associated antigen 6 interactome and its role in spermatogenesis.

CDC7 TTC8 APPL2 MEIOC INTS2 SNX25 FAM209B

5.91e-05199170731146259
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RBM15 POLR2G PPP4R3A CASK CDC42EP1 PPP4R3B ARHGAP5 PTPRD PTPRF SSH1 PTPRS SUPT16H MKI67 GNL2 SENP2 FKBP4

6.16e-0510491701627880917
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

RPL28 RBM15 SET FYTTD1 RAE1 RPS11 RBM28 NGDN RBM27 SUPT16H GNL2 TLN2 TOP1

6.83e-057311701329298432
Pubmed

Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions.

TLN1 TLN2

7.10e-053170212422220
Pubmed

Immunohistochemical study of DNA topoisomerase I, p53, and Ki-67 in uterine carcinosarcomas.

MKI67 TOP1

7.10e-053170217490723
Pubmed

Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and the oncogenic regulator SET through interaction and acetylation on the DNA-binding domain.

SET EP300

7.10e-053170214612398
Pubmed

Disruption of eyelid and cornea development by targeted overexpression of the glucocorticoid receptor.

NR3C1 MKI67

7.10e-053170212653252
Pubmed

Analyzing Somatic Genome Rearrangements in Human Cancers by Using Whole-Exome Sequencing.

ROR1 ROS1

7.10e-053170227153396
Pubmed

Glucocorticoid receptor regulates PD-L1 and MHC-I in pancreatic cancer cells to promote immune evasion and immunotherapy resistance.

NR3C1 CD274

7.10e-053170234873175
Pubmed

PD-L1 expression in ROS1-rearranged non-small cell lung cancer: A study using simultaneous genotypic screening of EGFR, ALK, and ROS1.

CD274 ROS1

7.10e-053170230475455
Pubmed

Glucose deprivation inhibits multiple key gene expression events and effector functions in CD8+ T cells.

TLN1 TLN2

7.10e-053170218792400
Pubmed

Arginylation-dependent regulation of a proteolytic product of talin is essential for cell-cell adhesion.

TLN1 TLN2

7.10e-053170222665520
Pubmed

An essential role for talin during alpha(M)beta(2)-mediated phagocytosis.

TLN1 TLN2

7.10e-053170217202407
Pubmed

Mechanotransduction in talin through the interaction of the R8 domain with DLC1.

TLN1 TLN2

7.10e-053170230028837
Pubmed

Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway.

PTPRD PTPRF

7.10e-053170225703008
Pubmed

Vinculin and talin: focus on the myocardium.

TLN1 TLN2

7.10e-053170219952892
Pubmed

p300/CBP inhibition enhances the efficacy of programmed death-ligand 1 blockade treatment in prostate cancer.

CD274 EP300

7.10e-053170232203167
Pubmed

Activated glucocorticoid receptor interacts with the INHAT component Set/TAF-Ibeta and releases it from a glucocorticoid-responsive gene promoter, relieving repression: implications for the pathogenesis of glucocorticoid resistance in acute undifferentiated leukemia with Set-Can translocation.

SET NR3C1

7.10e-053170218096310
Pubmed

Prognostic value of programmed death ligand 1, p53, and Ki-67 in patients with advanced-stage colorectal cancer.

MKI67 CD274

7.10e-053170228782638
Pubmed

Talin depletion reveals independence of initial cell spreading from integrin activation and traction.

TLN1 TLN2

7.10e-053170219160486
Pubmed

Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.

PTPRD PTPRS

7.10e-053170225394468
Pubmed

Talin and vinculin are downregulated in atherosclerotic plaque; Tampere Vascular Study.

TLN1 TLN2

7.10e-053170227816808
Pubmed

Genome-wide association study of copy number variations (CNVs) with opioid dependence.

PTPRD CTNNA3

7.10e-053170225345593
Pubmed

Modulation of glucocorticoid receptor nuclear translocation in neurons by immunophilins FKBP51 and FKBP52: implications for major depressive disorder.

NR3C1 FKBP4

7.10e-053170219545546
Pubmed

Cytoskeletal proteins talin and vinculin in integrin-mediated adhesion.

TLN1 TLN2

7.10e-053170215494027
Pubmed

Role of Ki-67, MRE11, and PD-L1 as Predictive Biomarkers for Recurrence Pattern in Muscle-invasive Bladder Cancer.

MKI67 CD274

7.10e-053170234281845
Pubmed

FK506-binding proteins 51 and 52 differentially regulate dynein interaction and nuclear translocation of the glucocorticoid receptor in mammalian cells.

NR3C1 FKBP4

7.10e-053170215591061
Pubmed

Vinculin controls talin engagement with the actomyosin machinery.

TLN1 TLN2

7.10e-053170226634421
Pubmed

Nuclear factor of activated T cells (NFAT)-dependent transactivation regulated by the coactivators p300/CREB-binding protein (CBP).

NFATC2 EP300

7.10e-05317029625762
Pubmed

Loss of mouse cardiomyocyte talin-1 and talin-2 leads to β-1 integrin reduction, costameric instability, and dilated cardiomyopathy.

TLN1 TLN2

7.10e-053170228698364
InteractionCBX3 interactions

ZNF567 SET AHCTF1 RPS11 CHD1 SMARCAD1 TFE3 ZNF518A NFATC2 RBM27 ABCE1 SUV39H1 SUPT16H MKI67 TOP1 CWF19L1 FKBP4 EP300

4.34e-0664616118int:CBX3
InteractionNUP43 interactions

RBM15 RAE1 BAZ2B AHCTF1 CHD1 SMARCAD1 RBM28 MBIP ZNF518A BRCA2 SUPT16H MKI67 GNL2 SENP2 DNAH9 TOP1 ZNF687

1.11e-0562516117int:NUP43
InteractionNSUN2 interactions

ROR1 RPS11 RANBP6 RBM28 RPRD1B ABCE1 TLN1 ARIH2 PANK4 GNL2 CD274 ROS1

1.16e-0532316112int:NSUN2
InteractionPOLR3H interactions

RAE1 POLR2G MBIP RPRD1B RPRD1A APPL2 GNL2

1.47e-05991617int:POLR3H
InteractionPOLR1E interactions

BAZ2B POLR2G CHD1 SMARCAD1 RBM28 NR3C1 RPRD1B RPRD1A BRCA2 SUPT16H GNL2 ZNF687

2.56e-0535016112int:POLR1E
InteractionCCT8L2 interactions

DYNC2H1 KIF16B PEX1 SMARCAD1 NR3C1 MBIP BRCA2 NAV1

3.89e-051571618int:CCT8L2
InteractionABCE1 interactions

RPS11 RANBP6 ANKRD30B NR3C1 RPRD1B PTPRF ABCE1 KCTD10 SUPT16H GNL2 CD274 ROS1 EP300

4.45e-0543116113int:ABCE1
Cytoband20q13.31

RAE1 MYLK2 FAM209B

2.70e-0516170320q13.31
CytobandEnsembl 112 genes in cytogenetic band chr1p22

SPATA1 CDC7 CLCA2 BRDT SETSIP

1.65e-041371705chr1p22
GeneFamilyDyneins, axonemal

DNAH1 DNAH8 DNAH9

1.48e-04171123536
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRD PTPRF PTPRS

2.84e-04211123813
GeneFamilyOlfactory receptors, family 11

OR11H12 OR11H1 OR11H2

3.74e-04231123159
GeneFamilyFibronectin type III domain containing

PRTG TNC PTPRD PTPRF PTPRS ROS1

4.83e-041601126555
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

PRTG ROR1 PTPRD PTPRF PTPRS ALPK2

4.99e-041611126593
GeneFamilyOlfactory receptors, family 8

OR8H2 OR8J2 OR8D2

3.47e-03491123155
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP5 ARHGAP6 ARHGAP18

3.67e-03501123721
GeneFamilyIntegrator complex

INTS14 INTS2

3.79e-031511221366
CoexpressionGEORGES_CELL_CYCLE_MIR192_TARGETS

DLG5 TDG CDC7 RAD1 MKI67 TOP1

2.70e-06621666M11038
CoexpressionGSE32423_MEMORY_VS_NAIVE_CD8_TCELL_IL7_IL4_DN

FYTTD1 BAZ2B KIF16B SRP54 RPRD1A PTPRF SNX25 DEPDC5 FOXC2

5.52e-062001669M5081
CoexpressionNAKAYA_PBMC_FLUMIST_AGE_18_50YO_3DY_DN

ZNF567 RAE1 AHCTF1 CHD1 FRYL MBIP PPP4R3A SNX13 APPL2 RBM27 ARIH2 FAM209B SENP2 TOP1 CWF19L1 EP300

7.25e-0668016616M41089
CoexpressionGSE15330_HSC_VS_LYMPHOID_PRIMED_MULTIPOTENT_PROGENITOR_IKAROS_KO_DN

NUDT13 PPP4R3A PPP4R3B INTS14 ANGPTL4 CD274 CCL17 TOP1

4.01e-051981668M7035
CoexpressionGSE12845_IGD_POS_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_DN

BAZ2B RBM28 RPRD1A ERAL1 SUV39H1 MKI67 TOP1 NAA16

4.15e-051991668M3191
CoexpressionGSE40441_NRP1_POS_INDUCED_TREG_VS_NRP1_NEG_NATURAL_TREG_DN

BAZ2B PEX1 NUDT13 SPATA1 MYLK2 RPRD1A PLCH1 DNAH8

4.15e-051991668M9195
CoexpressionGSE2770_IL12_AND_TGFB_ACT_VS_ACT_CD4_TCELL_48H_DN

RAE1 THUMPD1 RANBP6 SMARCAD1 RBM28 CLPTM1L INTS14 SUV39H1

4.30e-052001668M6039
CoexpressionGSE40274_FOXP3_VS_FOXP3_AND_LEF1_TRANSDUCED_ACTIVATED_CD4_TCELL_DN

DYNC2H1 BAZ2B SMARCAD1 GSAP RPRD1A LUM ARHGAP18 DNAH8

4.30e-052001668M9188
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

CACNA1D COL8A1 TNC ROR1 TMTC2 GRIK4 PTPRD ANTXR1 LUM

6.72e-081971699f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL8A1 TNC CDC42EP1 SEMA3A PTPRD ERRFI1 ANTXR1 LUM FOXC2

7.02e-0819816999d61483b0decac2fe90045b3474843360b2c49b3
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

COL8A1 DYNC2H1 TNC CDC42EP1 PTPRD ERRFI1 ANTXR1 LUM FOXC2

7.02e-081981699bc9c9f2c87282b5ef8514773e065d2a6b5dde338
ToppCellControl-Epithelial_cells|Control / group, cell type (main and fine annotations)

COL8A1 ROR1 TMTC2 MBIP SNX25 ERRFI1 ROS1 PLCH1

6.29e-071881698707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ROR1 GSAP MBIP KIAA1217 ERRFI1 CTNNA3 ROS1 PLCH1

6.82e-0719016988aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC26A9 MBIP PTPRD SNX25 KIAA1217 ERRFI1 ROS1 PLCH1

7.38e-071921698fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

CACNA1D TNC GRIK4 ARHGAP6 PTPRD PTPRS ANTXR1 LUM

7.67e-071931698acad568621ed677031797b8c2e34dafea798d681
ToppCellFetal_29-31_weeks-Epithelial|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

GSAP MBIP PTPRF KIAA1217 ERRFI1 CTNNA3 ROS1 PLCH1

7.67e-071931698a0ca3231992f14abcf1a6129573bace320e89d2a
ToppCellnucseq-Epithelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

COL8A1 ROR1 TMTC2 MBIP PTPRF SNX25 ROS1 PLCH1

8.29e-0719516989406866f99555198a9be311fbd65751b70f35446
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1D GRIK4 ARHGAP6 PTPRS AASS ANTXR1 TLN2 LUM

8.62e-071961698bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CACNA1D COL8A1 TNC PTPRD PTPRS AASS ANGPTL4 LUM

1.00e-062001698aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CACNA1D COL8A1 TNC PTPRD PTPRS AASS ANGPTL4 LUM

1.00e-062001698a510deaada669e690329183e18df02870bd204b3
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CACNA1D COL8A1 TNC PTPRD PTPRS AASS ANGPTL4 LUM

1.00e-062001698dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D CES1 BAZ2B ROR1 MBIP KIAA1217 LUM

5.22e-061771697b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HTR2B ROR1 GRIK4 NAV1 PPP1R1C CCL17 ALPK2

5.83e-06180169732d871738a24071b70084a7e80148a516110c78b
ToppCellBAL-Mild-Myeloid-cDC-cDC-cDC_10|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HTR2B ROR1 GRIK4 NAV1 PPP1R1C CCL17 ALPK2

5.83e-061801697067ca8a15228c7f3b3bc7aecbc9b1611ca05e176
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D ABCC3 SLC3A1 ARHGAP6 PTPRD TLN2 ALPK2

7.22e-061861697b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TNC CDC42EP1 SEMA3A ANGPTL4 ERRFI1 LUM FOXC2

7.48e-061871697f1d0fc625e0e7881b3f290742fd7148d995eb71e
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TNC CDC42EP1 SEMA3A ANGPTL4 ERRFI1 LUM FOXC2

7.48e-06187169702e7246ef5ad41773d14426254e139b156d45c1d
ToppCell10x3'2.3-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

TNC CDC42EP1 SEMA3A ANGPTL4 ERRFI1 LUM FOXC2

7.48e-06187169708c73d125e0638c9e9878165bba2442c266c8a48
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1D CES1 DYNC2H1 GRIK4 ARHGAP6 PTPRD LUM

8.02e-061891697203c80030df08ae112f9ae4043709f455d87ce89
ToppCell(1)_Osterolineage_cells-(10)_OLC-1|World / Cell class and subclass of bone marrow stroma cells in homeostatis

COL8A1 PLB1 TNC TMTC2 PTPRD PTPRS LUM

8.02e-06189169746c5b975fb9d33017f2d9b7770d45a8bdf95baa2
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D TNC ARHGAP6 PTPRD PTPRS ANTXR1 LUM

8.02e-0618916972a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SET BAZ2B SMARCAD1 NR3C1 ZNF518A PPP4R3B ARHGAP5

8.59e-06191169760c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MBIP PTPRD KIAA1217 ERRFI1 CTNNA3 ROS1 PLCH1

8.59e-06191169734cc997e4e5c727495f321e6807a84aa124da486
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ROR1 GSAP MBIP KIAA1217 CTNNA3 ROS1 PLCH1

8.59e-061911697ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SET BAZ2B SMARCAD1 NR3C1 ZNF518A PPP4R3B ARHGAP5

8.59e-061911697973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellEpithelial|World / Lineage, Cell type, age group and donor

COL8A1 MBIP PTPRF SNX25 KIAA1217 ROS1 PLCH1

8.89e-061921697499e8893afea5e6d3371e0bd018f7e86a524d669
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

PRTG SLC26A9 MBIP SNX25 ERRFI1 ROS1 PLCH1

8.89e-061921697cc9911e182a289779a2612bc213daae5607689e7
ToppCellAdult-Epithelial|Adult / Lineage, Cell type, age group and donor

COL8A1 ROR1 TMTC2 PTPRF SNX25 KIAA1217 PLCH1

8.89e-061921697efb962a5fd3b9bdfd8cf8d13c435e29c8271713e
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D TNC ROR1 ARHGAP6 PTPRD ANTXR1 LUM

8.89e-061921697deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRTG SLC26A9 MBIP PTPRD SNX25 ROS1 PLCH1

9.19e-061931697fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIL1 ABCC3 FRYL DYRK4 PTPRF CLCA2 MUC2

9.19e-061931697402aad2f9e789ad1f2e1536cdc9ce61de7625427
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL8A1 TNC CDC42EP1 KIAA1217 ERRFI1 LUM FOXC2

9.19e-0619316975e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

CACNA1D GRIK4 ARHGAP6 PTPRS ANGPTL4 ANTXR1 LUM

9.19e-061931697ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-goblet-Goblet_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VIL1 ABCC3 FRYL DYRK4 PTPRF CLCA2 MUC2

9.19e-0619316977ee3b1ef5c455f321b4e154ae62c69543fe9b30e
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PRTG SLC26A9 MBIP PTPRD SNX25 ROS1 PLCH1

9.19e-061931697f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1D ROR1 GRIK4 ARHGAP6 PTPRD ANTXR1 LUM

9.51e-061941697b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D TNC ARHGAP6 PTPRD PTPRS ANTXR1 LUM

9.51e-06194169760622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D TNC ARHGAP6 PTPRD PTPRS ANTXR1 LUM

9.51e-0619416976e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell10x5'-blood-Hematopoietic_Erythro-Mega-Megakaryocyte_early|blood / Manually curated celltypes from each tissue

VIL1 ABCC3 FAXDC2 XPNPEP1 ARHGAP6 TLN1 ARHGAP18

9.51e-06194169763dea7d630962761a70aa88e720ee35c22cbc81a
ToppCell10x5'-blood-Hematopoietic_Erythro-Mega|blood / Manually curated celltypes from each tissue

VIL1 ABCC3 FAXDC2 XPNPEP1 ARHGAP6 TLN1 ARHGAP18

9.51e-061941697d0e7d35b5086834929c4bd39d4c6719b2d5fc71e
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.2.4|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SET SLC26A9 MBIP SNX25 ERRFI1 ROS1 TOP1

9.51e-06194169754975e663ed4414b99b3c9a1aa6335613946470f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1D ROR1 GRIK4 ARHGAP6 PTPRD ANTXR1 LUM

9.83e-0619516970e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellPCW_07-8.5-Mesenchymal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CACNA1D ROR1 SEMA3A ARHGAP6 PTPRD ANTXR1 LUM

1.02e-0519616978e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma-osteoblast_precursor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL8A1 TNC CDC42EP1 SEMA3A PTPRD LUM FOXC2

1.02e-05196169757df2a57b35be9851ac0b1e5731baa53052511f0
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1D ROR1 SEMA3A ARHGAP6 PTPRD ANTXR1 LUM

1.05e-05197169773a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1D ROR1 GRIK4 SEMA3A PTPRD ANTXR1 LUM

1.09e-05198169717dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCellParenchymal-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRTG SLC26A9 MBIP PTPRD SNX25 ROS1 PLCH1

1.09e-0519816972e2a4e1756bba6f4fbe529559a97d2993c890b4b
ToppCellFibroblasts-HLA-DRA_high_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

COL8A1 DYNC2H1 TNC C1RL CDC42EP1 ANTXR1 LUM

1.09e-051981697e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

CACNA1D GRIK4 ARHGAP6 PTPRD PTPRS ANTXR1 LUM

1.09e-051981697df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

COL8A1 ROR1 TMTC2 MBIP SNX25 ROS1 PLCH1

1.12e-051991697725610310e5c5fd7120c0be9acb55bf152026ddd
ToppCellPCW_10-12-Mesenchymal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1D ROR1 SEMA3A ARHGAP6 PTPRD ANTXR1 LUM

1.12e-051991697a09292de4c4447b8eee55d401808e43b817321cc
ToppCelltumor_Lung-Epithelial_cells-tS2|tumor_Lung / Location, Cell class and cell subclass

ABCC3 HEBP2 TNC CDC42EP1 CLPTM1L PTPRF ERRFI1

1.12e-05199169728ec59e01061287fb0892491790b316e2b93e232
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DLG5 CES1 TNC ARHGAP5 PTPRF CLCA2 KIAA1217

1.16e-05200169797f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellMS-Multiple_Sclerosis-Others-Platelet|Multiple_Sclerosis / Disease, condition lineage and cell class

VIL1 ABCC3 AHCTF1 FAXDC2 XPNPEP1 ARHGAP6 ARHGAP18

1.16e-052001697263d956136747c209951b4358f2e1672a21d8eef
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL8A1 TNC CDC42EP1 PTPRD ERRFI1 LUM FOXC2

1.16e-0520016973c898e81444b001835c3f1bbc68183078701b135
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

COL8A1 TNC CDC42EP1 PTPRD ERRFI1 LUM FOXC2

1.16e-0520016973eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCellmetastatic_Lymph_Node-Epithelial_cells-Malignant_cells|Epithelial_cells / Location, Cell class and cell subclass

ABCC3 TNC MBIP CDC42EP1 CLPTM1L ERRFI1 TOP1

1.16e-052001697b16da9c342f9ff5ed4983c65b7d3b59123a594cd
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1RL F9 PTPRD PTPRF ANGPTL4 ERRFI1

2.93e-051561696e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellASK452-Epithelial-Type_2|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

HEATR4 DLGAP4 RAD1 SENP2 ROS1 ZNF649

2.93e-051561696e2b8d65c38cedb8ec6c3c1b138957145af931c51
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

KCNH7 GRIK4 SEMA3A CTNNA3 DNAH8 DNAH9

3.26e-0515916965335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellCOVID-19-Heart-CM_+_Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

ABCC3 NRAP CTNNA3 PPP1R1C DDX60L ARHGAP18

4.74e-0517016964232fe937909f93d3736988c707b8f95ce993398
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

THUMPD1 DYRK4 CDC7 ARHGAP5 MKI67 DDX4

4.74e-051701696badbe200e9d5003d23d115955b10b4ea767f6c26
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_NK|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC26A9 CDC7 ESCO2 MKI67 PLCH1 ALPK2

4.90e-0517116961eebd7138c3b20ddc1104f21615f9df0e776bbe6
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THUMPD1 DYRK4 CDC7 NFATC2 CCL17 DDX4

5.22e-05173169615af4a0f7516dbf5c93ba66a19aca073ebe30d04
ToppCell367C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ESCO2 TRIM45 BRCA2 SUV39H1 MKI67 PPP1R1C

5.57e-0517516960b1aaa028ba844d4bcb4509fdab8bee648373935
ToppCellCOVID-19-Heart-CM_3|COVID-19 / Disease (COVID-19 only), tissue and cell type

NRAP ROR1 CTNNA3 PPP1R1C DDX60L ALPK2

5.75e-0517616969df7a124ebafb0087da0cda133a394275d7bed81
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 SRP54 NR3C1 ARHGAP5 IBTK SUPT16H

5.75e-051761696749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRTG TNC ROR1 ARHGAP6 KIAA1217 PLCH1

6.71e-051811696af92b8b7f455210dab502ef6964f3a0162180759
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D TNC PEG3 TTC8 PTPRD LUM

6.71e-0518116969e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDC7 ESCO2 SNX25 SUV39H1 MKI67 DNAH8

6.92e-051821696bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCell10x5'-bone_marrow-Hematopoietic_Erythro-Mega-Megakaryocyte_early|bone_marrow / Manually curated celltypes from each tissue

VIL1 ABCC3 FAXDC2 ARHGAP6 ARHGAP18 PLCH1

7.13e-0518316963cc9f3dc3bc4bde1d3408b0a6ba58e135a11036d
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D TNC ROR1 PEG3 PTPRS FOXC2

7.13e-0518316967eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Mesenchymal-skeletal_muscle_satellite_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1D RPL28 PEG3 RPS11 NFATC2 TLN2

7.13e-0518316967534587fa35837c0aaca93c542f2eee493eba637
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH1 PTPRD TLN2 ROS1 PLCH1 DNAH9

7.35e-0518416962cbed6462fea2622871bb7e49b0df3d984239281
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROR1 GSAP MBIP PTPRF KIAA1217 ERRFI1

7.35e-05184169642ce855b4f8475a8298192feec785bdc69bc5bb0
ToppCellCOVID-19-Epithelial_cells-AT2|COVID-19 / group, cell type (main and fine annotations)

PRTG SLC26A9 MBIP SNX25 ROS1 PLCH1

7.35e-051841696369b82f793deab672204558ae4e112cfa5aa9ccc
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH1 PTPRD TLN2 ROS1 PLCH1 DNAH9

7.35e-051841696ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH1 PTPRD TLN2 ROS1 PLCH1 DNAH9

7.35e-0518416962b19a8c5f823e00812908b23e66bb4e563278aff
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIL1 SLC3A1 PTPRD AASS ERRFI1 TLN2

7.57e-0518516963e3217c99719fd1d2fa94e16be7712a7e5077152
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIL1 SLC3A1 PTPRD AASS ERRFI1 TLN2

7.57e-0518516960ff4148b4701003d9d594e0da8261176fb13aa59
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.4.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL8A1 SLC26A9 MBIP CDC42EP1 SNX25 ROS1

7.57e-0518516967460387f48f33674330bd53b759681b264228f5a
ToppCellMesenchymal_cells-Osteo-CAR|World / Lineage and Cell class

COL8A1 PLB1 TNC CDC42EP1 PTPRD ANGPTL4

7.57e-05185169616f1588893d09c864e0cb4f837a1b972a1a57baa
ToppCellMegakaryocytic-erythropoietic-Megakaryo-cells-Platelet|World / Lineage, cell class and subclass

ABCC3 FAXDC2 XPNPEP1 ARHGAP6 TLN1 ARHGAP18

7.80e-05186169627807334e7241c8a9aeaf6403f0fd0b001fbc0d1
ToppCellEpithelial-C_(AT2)|World / shred on cell class and cell subclass (v4)

SLC26A9 GSAP MBIP PTPRF SNX25 ERRFI1

7.80e-051861696b7b1763fc52b4485d843a4a6727055e6c95ebad3
ToppCellMesenchymal_cells-Adipo-CAR|World / Lineage and Cell class

COL8A1 TNC PTPRD ANGPTL4 ERRFI1 ANTXR1

7.80e-0518616966ca8ce7ced91d6308b7c056032ffec1b37c974bf
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-23|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ROR1 PEG3 GSAP SACS ERRFI1 TLN2

8.03e-05187169669b47f00598d647e2a99427ebddf42c339428e47
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CACNA1D ROR1 GRIK4 SEMA3A ARHGAP6 PTPRD

8.03e-051871696a9316e2818217ec5feae9cf8816f7249803caee6
ToppCellCOPD-Epithelial-ATII|Epithelial / Disease state, Lineage and Cell class

TNC SLC26A9 MBIP SNX25 ROS1 TOP1

8.03e-051871696030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCelldroplet-Kidney-nan-18m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC3A1 ARHGAP5 PTPRD PTPRF AASS ERRFI1

8.03e-051871696236e9857729670e87eed30fad58f49e1f56e4a85
ToppCellMonocytes-M2-like_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

BAZ2B GSAP ARHGAP5 ARHGAP6 BRCA2 ARHGAP18

8.03e-05187169659e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

COL8A1 RMI1 PTPRD PTPRS ANTXR1 LUM

8.27e-0518816968231e635706a296db6b6da1029a33bbc1b52478e
ToppCell21-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

CFAP107 CES1 DYNC2H1 VWA3B DNAH9 LRRC23

8.27e-051881696803bf76a85b3033d2a04b08dd2c03ce9c15529ba
ToppCellCOVID-19-Epithelial_cells|COVID-19 / group, cell type (main and fine annotations)

MBIP PTPRF SNX25 KIAA1217 ROS1 PLCH1

8.27e-051881696c9cdee6f8d42ee69f5fb335f25084603c511bd29
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC26A9 GSAP MBIP PTPRF SNX25 ERRFI1

8.27e-0518816967499e353ea5853d06558b20cedee3c7910425d7d
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC26A9 GSAP MBIP PTPRF SNX25 ERRFI1

8.27e-051881696562f5984efdbbcb8f53ddcee033ccbf9eb678425
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D231|Adult / Lineage, Cell type, age group and donor

PRTG SLC26A9 MBIP SNX25 ROS1 PLCH1

8.52e-051891696dab54a52358f66a8a9460cd6089a06c5fa7e7a5d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1D TNC ARHGAP6 PTPRD ANTXR1 LUM

8.52e-051891696a153b83314cf52808f685296cff8c95af3f4983d
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC26A9 MBIP PTPRF AASS SNX25 ERRFI1

8.77e-0519016968ff8c586237cf15f930416710bcff45205fe6f70
DrugAC1MIXXG

BAZ2B SMARCAD1 ESCO2 BRDT SUPT16H EP300

8.69e-08311666CID003081982
DrugCisapride [81098-60-4]; Down 200; 8.6uM; PC3; HT_HG-U133A

ABCC3 ROR1 DLGAP4 KCNAB2 PEX1 C1RL NR3C1 PPP4R3A SEMA3A SENP2

1.76e-06195166106706_DN
Diseaseautosomal recessive spinocerebellar ataxia 20 (implicated_via_orthology)

SNX13 SNX25

2.92e-0521602DOID:0080066 (implicated_via_orthology)
Diseasephosphatidylcholine 38:6 measurement

ABCC3 AHCTF1 DEPDC5

8.32e-05161603EFO_0010388
DiseaseMalignant neoplasm of breast

DYNC2H1 ROR1 KIF16B SEMA3A CLPTM1L PTPRD RPRD1A CLCA2 BRCA2 SPATA21 ANGPTL4 MKI67 PACC1 DNAH9 TOP1 EP300

2.56e-04107416016C0006142
Diseasemucositis (biomarker_via_orthology)

MKI67 MUC2

2.89e-0451602DOID:0080178 (biomarker_via_orthology)
Diseaseazoospermia (implicated_via_orthology)

PTPRD PTPRF PTPRS

4.16e-04271603DOID:14227 (implicated_via_orthology)
Diseasestearoyl sphingomyelin (d18:1/18:0) measurement

CAMTA2 ANGPTL4

4.32e-0461602EFO_0800611
Diseasegeneralized anxiety disorder (implicated_via_orthology)

HTR2B NR3C1

8.01e-0481602DOID:14320 (implicated_via_orthology)
Diseasecataract (implicated_via_orthology)

NR3C1 BRCA2 PANK4

1.15e-03381603DOID:83 (implicated_via_orthology)
Diseaselung cancer (is_marker_for)

TNC ESCO2 MKI67

1.24e-03391603DOID:1324 (is_marker_for)
Diseaselong QT syndrome (implicated_via_orthology)

KCNH7 ARHGAP6

1.28e-03101602DOID:2843 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

HTR2B DLGAP4 CHD1 CASK NAA16

1.47e-031521605DOID:0060041 (implicated_via_orthology)
DiseaseBarrett's esophagus (is_marker_for)

MKI67 MUC2

1.56e-03111602DOID:9206 (is_marker_for)
DiseaseColorectal Carcinoma

ABCC3 PEG3 CHD1 PTPRD SACS PTPRS ABCE1 PANK4 MKI67 DNAH8 EP300

1.62e-0370216011C0009402
Diseaseoptic disc area measurement

COL8A1 CDC42EP1 CTNNA3

1.88e-03451603EFO_0006937
Diseaseresponse to antineoplastic agent

KIF16B SMARCAD1 SEMA3A PTPRD

2.10e-03991604GO_0097327
Diseaseurate measurement, bone density

PLB1 BAZ2B AHCTF1 DNAH1 PTPRD ARIH2 NAV1 VWA3B DNAH8 DNAH9

2.11e-0361916010EFO_0003923, EFO_0004531
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

CES1 SNX13 DNAH1 RMI1 KCTD10 ANGPTL4

2.17e-032431606EFO_0004612, EFO_0020944
DiseaseBenign tumor of pancreas

BRCA2 EP300

2.19e-03131602C0347284
DiseaseX-24588 measurement

ABCC3 HEATR4

2.19e-03131602EFO_0800898
Disease1-methylurate measurement

SEMA3A PTPRF

2.55e-03141602EFO_0021173
Diseaseunipolar depression, mood disorder, response to antidepressant

PTPRD ERRFI1

2.55e-03141602EFO_0003761, EFO_0004247, GO_0036276
Diseasepathological myopia

ZNF285 PTPRD ROS1 DNAH9

3.18e-031111604EFO_0004207
Disease5-oxoproline measurement

RMI1 DNAH8

3.34e-03161602EFO_0010988
Diseasecancer (implicated_via_orthology)

POLR2G RANBP6 PGK2 BRCA2 DEPDC5 TOP1

3.51e-032681606DOID:162 (implicated_via_orthology)
DiseaseDrug habituation

APPL2 CTNNA3 CD274 DNAH8

3.61e-031151604C0013170
DiseaseDrug abuse

APPL2 CTNNA3 CD274 DNAH8

3.61e-031151604C0013146
DiseasePrescription Drug Abuse

APPL2 CTNNA3 CD274 DNAH8

3.61e-031151604C4316881
DiseaseSubstance-Related Disorders

APPL2 CTNNA3 CD274 DNAH8

3.61e-031151604C0236969
DiseaseDrug Use Disorders

APPL2 CTNNA3 CD274 DNAH8

3.61e-031151604C0013222
DiseaseDrug Dependence

APPL2 CTNNA3 CD274 DNAH8

3.61e-031151604C1510472
DiseaseSubstance Dependence

APPL2 CTNNA3 CD274 DNAH8

3.61e-031151604C0038580
DiseaseSubstance Use Disorders

APPL2 CTNNA3 CD274 DNAH8

3.61e-031151604C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

APPL2 CTNNA3 CD274 DNAH8

3.61e-031151604C0029231
DiseaseSubstance abuse problem

APPL2 CTNNA3 CD274 DNAH8

3.72e-031161604C0740858
Diseasepre-malignant neoplasm (biomarker_via_orthology)

SUV39H1 MUC2

3.77e-03171602DOID:0060071 (biomarker_via_orthology)
DiseaseColorectal Neoplasms

ABCC3 CHD1 PTPRD ABCE1 MKI67 EP300

4.13e-032771606C0009404
Diseasepursuit maintenance gain measurement

CACNA1D GSAP PTPRD DDX60L

4.59e-031231604EFO_0008433
DiseasePancreatic carcinoma

BRCA2 EP300

4.70e-03191602C0235974
DiseaseDeaf Mutism

CACNA1D TMTC2

5.21e-03201602C4082305
DiseaseDeafness, Acquired

CACNA1D TMTC2

5.21e-03201602C0751068
DiseaseHearing Loss, Extreme

CACNA1D TMTC2

5.21e-03201602C0086395
DiseaseComplete Hearing Loss

CACNA1D TMTC2

5.21e-03201602C0581883
Diseaseresponse to COVID-19 vaccine, SARS-CoV-2 neutralizing antibody measurement

PTPRD FAM209B

5.21e-03201602EFO_0803359, EFO_0803362
DiseaseBilateral Deafness

CACNA1D TMTC2

5.21e-03201602C3665473
Diseaseblood aluminium measurement

BAZ2B TRIM45

5.21e-03201602EFO_0007575
DiseasePrelingual Deafness

CACNA1D TMTC2

5.21e-03201602C0011052

Protein segments in the cluster

PeptideGeneStartEntry
VQKLQKYQPRIAVFN

TDG

216

Q13569
SRRQQQKYLGKNSKP

USP26

621

Q9BXU7
YLQIGANTQAAQKLK

CES1

526

P23141
KQRAAKYANSNPQPI

EP300

2086

Q09472
SNKPAVKLLYNRSNN

KCTD10

156

Q9H3F6
AIKKPIQANQYNSRA

HTR2B

156

P41595
GQYFRSIPQQRQKLK

ANGPTL4

361

Q9BY76
AQRKSKSPKINLNYA

ANKRD30B

1236

Q9BXX2
CINFTRVKNNQPAKY

ANTXR1

481

Q9H6X2
NNIAKAGYTKLTPVQ

DDX4

301

Q9NQI0
QENLVKTGRYNPAKQ

CCDC169

176

A6NNP5
PVIKVNSKQRYASNA

DNPEP

381

Q9ULA0
NTKKNGRLTNQLQYL

BRDT

21

Q58F21
GLRSSQQNPKVQKYI

ALPK2

256

Q86TB3
REQYKQAFPSQLKKQ

BAZ2B

431

Q9UIF8
LNSQIKNLSKLLPQY

ADAM18

171

Q9Y3Q7
QIEQLGKKYNINPVS

AASS

516

Q9UDR5
KTRPQNGSIILYNRK

CAMTA2

66

O94983
NKFLARYVSLPNQNK

ABHD4

41

Q8TB40
PNNKRVKNAVKYLQS

CCL17

76

Q92583
SGPRKKLFEYQQAQL

ARIH2

436

O95376
NLQRTKVRYNPSLKG

CA6

51

P23280
KPQAKQLQTRADYLI

CHD1

1296

O14646
QAPKIAQIKRNLSYG

DLGAP4

751

Q9Y2H0
YPSVRQKALNALNNI

ARMCX4

2096

Q5H9R4
YANRAKNIINKPTIN

KIF16B

351

Q96L93
NNQRIKASIPSIKYC

PGK2

36

P07205
NPQKKNYIFLRNAAE

RAE1

346

P78406
RPLRNLVSYLKQKQA

RBM15

886

Q96T37
QNKPGFLRKNQYTNT

RBM27

586

Q9P2N5
NQLVEQYKQKLLGPS

RBM28

731

Q9NW13
ITVKVNAPYNKINQR

CD274

126

Q9NZQ7
NQTQVNRYKISLLKP

RAD1

216

O60671
LLESKINPNTAYQKQ

PPP4R3A

51

Q6IN85
FGKALNPKRYQQTLE

ABCC3

711

O15438
SQRGQPLTKIQTLKY

MSGN1

156

A6NI15
LQLPYSKRKFSGQQR

DEPDC5

1511

O75140
VNFYVINGKRKRSQP

NFATC2

656

Q13469
NPLIYSLRNKEVKNA

OR8H2

286

Q8N162
LYDKINTKSSPQIRN

CASK

386

O14936
NPLIYSLQNKEIKAA

OR11H2

301

Q8NH07
NPLIYSLRNKDVKNA

OR8D2

286

Q9GZM6
NSRGKIIKPLQYQST

GNL2

51

Q13823
PAYQRAKKANQLASQ

NRAP

176

Q86VF7
NVPRQIQAKYLKGRT

IBTK

271

Q9P2D0
SNLNKYSTINKIPQL

KCNH7

321

Q9NS40
TAGYNSPVKLLNRNN

HEBP2

176

Q9Y5Z4
GRKYIPAKFQNANLS

DDX60L

1476

Q5H9U9
KKAPIQTYVLGANNQ

CWF19L1

61

Q69YN2
QSPSKQRSLYLLNKK

IBA57-DT

91

B1ANH7
GINLPKLKNLYLAQN

LRRC23

196

Q53EV4
VNPIIYSFRNKEIKN

OR5A2

286

Q8NGI9
QVQVNRQAVALPYKK

MUC2

4561

Q02817
RRYNPNEKLKVNFGT

MYLK2

431

Q9H1R3
LKLYDNPLTNESKQQ

NAA16

566

Q6N069
LFYVKKNNSQPQSLL

CSNKA2IP

596

A0A1B0GTH6
RTPLKKNQNASLYKD

FAM209B

96

Q5JX69
LLSNRYNAPFKKNIQ

DNAH8

1461

Q96JB1
VKTLKQYLLTQAQPG

ERAL1

316

O75616
NANKILNRPKRYNSG

F9

36

P00740
NKYAANRKSTGQLNL

FRYL

1906

O94915
LQPSIKFVRQQKYTQ

INTS2

836

Q9H0H0
ENAQKIQRGQIPSKY

DLG5

1641

Q8TDM6
SEKAINRNYLKQPVV

LCA5L

76

O95447
IITNQIPKYSNGNIK

NR3C1

756

P04150
QNAPEKKITLNGIYQ

FOXC2

86

Q99958
RENGNVAKTPRNTYK

MKI67

836

P46013
LLESKINPNTAYQKQ

PPP4R3B

51

Q5MIZ7
ATALKRKGPYTQQQN

NUDT13

306

Q86X67
FIPGQSLKRRQKTYN

PEG3

666

Q9GZU2
SPKRQLQFYRNLGKS

KCNAB2

31

Q13303
NPIIYSFRNKDVKNA

OR5AS1

286

Q8N127
SNLEVNKPKNRYANV

PTPRS

1411

Q13332
NYIDQRPAAKKSAQL

PACC1

266

Q9H813
NKLQTLRQQPFAYGT

PANK4

486

Q9NVE7
LIINSYGPIIKNNSK

PRTG

1036

Q2VWP7
NPLIYSLRNKNVKDA

OR8J2

286

Q8NGG1
FVASLLPFGNKRQNK

ARHGAP6

311

O43182
YLAFKRQQDLKSPNQ

CTNNA3

186

Q9UI47
EPVLLKQTYKQQGNT

DNAH1

3291

Q9P2D7
QDSPQQLLQAFLKYK

DYNC2H1

411

Q8NCM8
NITNNRGKKRYPDSK

DYRK4

346

Q9NR20
VTRLLQNYKKQPRNS

GSAP

781

A4D1B5
KPNFISRYRIQVGKN

FAXDC2

106

Q96IV6
NNYRPRINKLNSIKD

ABCE1

571

P61221
QLAATKKTQYQQLPV

BRCA2

3026

P51587
LQKYLNFDPRTAQKI

CAPN7

501

Q9Y6W3
VKRPYTNAQIQIKQG

CDC7

256

O00311
LQPKNKRSYAQNVTV

INTS14

391

Q96SY0
GLYEQLKQRQLTPKA

CFAP107

141

Q8N1D5
NLNRYNKQLSKVFPE

HEATR4

376

Q86WZ0
IKNAISLPQLNQAAY

CDC42EP1

116

Q00587
YPKDSVSLRKNQSVN

C1RL

286

Q9NZP8
NLIQKAGYLNLRNKT

APPL2

276

Q8NEU8
APVKFNKLLYNGRQN

COL8A1

631

P27658
LSYNKLKNIPTVNEN

LUM

261

P51884
NSRNSKQNRVIYKPI

ESCO2

161

Q56NI9
KRRKVQPPQQNYSLA

MBIP

301

Q9NS73
RANYVPALKLNQTLK

AHCTF1

961

Q8WYP5
SEKSQYNLSQPLLKR

DNAH9

671

Q9NYC9
QLYPNNKAAKTQLAV

FKBP4

381

Q02790
NSKGQRSNYALKILQ

GRIK4

366

Q16099
KAQTILAQYLDPQAK

GRK1

106

Q15835
LNYLQSSGKQIAKVP

SACS

591

Q9NZJ4
LYESFQNPKRRKNQS

PEX1

1256

O43933
PVGSLSQRKRQQYAK

CACNA1D

76

Q01668
NLEVNKPKNRYANVI

PTPRF

1371

P10586
NPLIYSLQNKEIKAA

OR11H1

301

Q8NG94
NPLIYSLQNKEIKAA

OR11H12

301

B2RN74
NLEVNKPKNRYANVI

PTPRD

1376

P23468
NTLPKKGLRYQLQSQ

NAV1

941

Q8NEY1
TERAYQKQPTIFQNK

RPS11

6

P62280
KQYLRNSNLTPQQKI

MEIOC

206

A2RUB1
QKYKQKLQTTQAPSL

SNX13

951

Q9Y5W8
NLLVERNKKQGYPAL

SENP2

421

Q9HC62
KLNKVQYSTRPGVND

TRIM45

356

Q9H8W5
YLANDVIQNSKRKGP

RPRD1B

61

Q9NQG5
DQLKQNATKARIPFY

SRP54

146

P61011
LNQSLSLKPYQKVGL

SMARCAD1

491

Q9H4L7
SILSRLKQQNYAPNL

SPATA21

381

Q7Z572
NPKTYNRAQDIQGIK

SLC26A9

516

Q7LBE3
SQPAYSQIQKLRGKN

RMI1

96

Q9H9A7
EYKRQALNSIQNAPK

SNX25

456

Q9H3E2
LQNASPKQRKQSVYT

PPP1R1C

61

Q8WVI7
KSQAPKNYQVLLGNI

PRSS47P

126

A8MTI9
QKYNKLRQPFFQKRS

SETSIP

81

P0DME0
KQSKLQDPRQYRQAN

KIAA1217

1766

Q5T5P2
QKYNKLRQPFFQKRS

SET

71

Q01105
QKTQPRSALKLYQDL

SLC3A1

541

Q07837
NLQPYIKRAAASKLQ

ARHGAP5

111

Q13017
NYQNGKNNVPRLKLS

SEMA3A

21

Q14563
NSNYLTRLQKPQDKL

PLB1

346

Q6P1J6
NKQTYSTEPNNLKAR

RPL28

21

P46779
QIQKARKSNVSYKNP

SUPT16H

501

Q9Y5B9
KQEFYQLLKNLINPS

RANBP6

16

O60518
PKYVSSKALQRQNSE

ERRFI1

356

Q9UJM3
NPLIYSLRNKDVNKA

OR5L2

286

Q8NGL0
DPSLANYLVQKAKQR

SUV39H1

111

O43463
RPKNLANITDSKNYL

SPATA1

386

Q5VX52
NYVKQKRSITRPNAG

SSH1

421

Q8WYL5
QNASRSFEKAKPNIY

CCDC54

226

Q8NEL0
NVSVPKKTRNNGTLY

CLPTM1L

91

Q96KA5
KPFYINGQNQIKVTR

CLCA2

181

Q9UQC9
QLVAIKTLKDYNNPQ

ROR1

501

Q01973
KNNIPANFTRSGNKL

FYTTD1

166

Q96QD9
IYKGNITPQLNKNTL

UHRF1BP1L

671

A0JNW5
NPSVYNKKRRATNIE

ZNF567

236

Q8N184
KAPYANTKRLQEENL

VIL1

601

P09327
NAVQKYLKNDVGRSP

TTLL8

451

A6PVC2
NLSRLNLTKYSQKPK

TTC8

176

Q8TAM2
LVVPVKTKYNFNNRG

XPNPEP1

541

Q9NQW7
QVKSLTQKVQAGAYP

NGDN

31

Q8NEJ9
RQQVKQYLSTTLGPK

TFE3

196

P19532
RYFGPNLLNTVKQKL

POLR2G

16

P62487
YLANDVIQNSKRKGP

RPRD1A

61

Q96P16
PKKSTVLQQQYNRVG

TLN1

426

Q9Y490
KLAQIRQQQYKFLPS

TLN1

2521

Q9Y490
YKLQTRPGFNKAQLA

SAP30L

126

Q9HAJ7
QKAEANYLRALQLKP

TMTC2

796

Q8N394
YTAKIQALNGPLRSN

TNC

1951

P24821
KPQAKRIIYFNDTAQ

ROS1

461

P08922
ELLKPKLVQNSTYQN

ZNF518A

1116

Q6AHZ1
SQTLRKKNKQYQIPD

ARHGAP18

156

Q8N392
TSQLASPLKLKYNQG

PLCH1

1381

Q4KWH8
KLAQIRQQQYKFLPT

TLN2

2521

Q9Y4G6
FNKILNSKNLLPAYR

ZNF687

501

Q8N1G0
LPSVYQKALGQREQK

TBCCD1

486

Q9NVR7
TLINPQGAKLNIYKR

VWA3B

906

Q502W6
ANKPIQYLENKTVLN

VWA3B

951

Q502W6
NSYEGQKQKVIQPRI

TMLHE

136

Q9NVH6
NIPAKILSYNRANRA

TOP1

611

P11387
IKNNILNLQAKGLSY

ZNF285

51

Q96NJ3
PNKGTFQIVYKSRNN

THUMPD1

191

Q9NXG2
PLQNQKILKRTGQRY

ZNF649

91

Q9BS31