Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-10 ERVK-24

4.44e-1737248GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-10 ERVK-24

5.62e-1738248GO:0070001
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 NYNRIN ERVK-7 ERVK-10

5.27e-1011244GO:0004523
GeneOntologyMolecularFunctionendopeptidase activity

ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-10 ERVK-24

2.36e-08430248GO:0004175
GeneOntologyMolecularFunctionRNA endonuclease activity, producing 5'-phosphomonoesters

ERVK-6 NYNRIN ERVK-7 ERVK-10

1.03e-0737244GO:0016891
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

ERVK-6 NYNRIN ERVK-7 ERVK-10

2.53e-0746244GO:0016893
GeneOntologyMolecularFunctionRNA-directed DNA polymerase activity

ERVK-6 ERVK-7 ERVK-10

5.50e-0714243GO:0003964
GeneOntologyMolecularFunctionpeptidase activity

ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-10 ERVK-24

5.86e-07654248GO:0008233
GeneOntologyMolecularFunctionRNA stem-loop binding

ERVK-6 ERVK-7 ERVK-10

2.00e-0621243GO:0035613
GeneOntologyMolecularFunctionRNA endonuclease activity

ERVK-6 NYNRIN ERVK-7 ERVK-10

2.27e-0679244GO:0004521
GeneOntologyMolecularFunctiontransition metal ion binding

CYP4X1 ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 MGAT5 ERVK-10 ERVK-24

5.28e-061189249GO:0046914
GeneOntologyMolecularFunctionstructural molecule activity

ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-10 ERVK-24

5.92e-06891248GO:0005198
GeneOntologyMolecularFunctionDNA polymerase activity

ERVK-6 ERVK-7 ERVK-10

1.25e-0538243GO:0034061
GeneOntologyMolecularFunctionRNA nuclease activity

ERVK-6 NYNRIN ERVK-7 ERVK-10

1.97e-05136244GO:0004540
GeneOntologyMolecularFunctionendonuclease activity

ERVK-6 NYNRIN ERVK-7 ERVK-10

1.97e-05136244GO:0004519
GeneOntologyMolecularFunctionzinc ion binding

ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 ERVK-10 ERVK-24

6.11e-05891247GO:0008270
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

ERVK-6 NYNRIN ERVK-7 DDX43 ERVK-10

1.19e-04417245GO:0140098
GeneOntologyMolecularFunctionnuclease activity

ERVK-6 NYNRIN ERVK-7 ERVK-10

1.55e-04231244GO:0004518
GeneOntologyMolecularFunctionnucleotidyltransferase activity

ERVK-6 ERVK-7 ERVK-10

7.78e-04152243GO:0016779
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

ERVK-6 NYNRIN ERVK-7 DDX43 ERVK-10

8.83e-04645245GO:0140640
GeneOntologyMolecularFunctionhydrolase activity, acting on ester bonds

ERVK-6 NYNRIN ERVK-7 AOAH ERVK-10

2.39e-03807245GO:0016788
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ERVK-6 ERVK-7 ERVK-10

3.69e-03262243GO:0140097
GeneOntologyMolecularFunctionphosphatase regulator activity

SBF2 MGAT5

8.08e-03113242GO:0019208
GeneOntologyBiologicalProcessDNA integration

ERVK-6 NYNRIN ERVK-7 ERVK-10

8.34e-1013234GO:0015074
GeneOntologyBiologicalProcessviral process

ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9 MGAT5 ERVK-10 ERVK-24

2.25e-08464238GO:0016032
GeneOntologyBiologicalProcessDNA synthesis involved in DNA repair

ERVK-6 NYNRIN ERVK-7 ERVK-10

2.21e-0748234GO:0000731
GeneOntologyBiologicalProcesscell-cell fusion

ERVK-6 ERVK-19 ERVK-21 ERVK-9

2.24e-0685234GO:0140253
GeneOntologyBiologicalProcesssyncytium formation by plasma membrane fusion

ERVK-6 ERVK-19 ERVK-21 ERVK-9

2.24e-0685234GO:0000768
GeneOntologyBiologicalProcesssyncytium formation

ERVK-6 ERVK-19 ERVK-21 ERVK-9

2.69e-0689234GO:0006949
GeneOntologyBiologicalProcessDNA-templated DNA replication

ERVK-6 NYNRIN ERVK-7 ERVK-10

4.18e-05178234GO:0006261
GeneOntologyBiologicalProcessDNA biosynthetic process

ERVK-6 NYNRIN ERVK-7 ERVK-10

9.18e-05218234GO:0071897
GeneOntologyBiologicalProcessRNA-templated DNA biosynthetic process

ERVK-6 ERVK-7 ERVK-10

1.05e-0483233GO:0006278
GeneOntologyBiologicalProcessDNA replication

ERVK-6 NYNRIN ERVK-7 ERVK-10

3.62e-04312234GO:0006260
GeneOntologyCellularComponentsuper elongation complex

AFF4 AFF3

1.58e-056222GO:0032783
GeneOntologyCellularComponenttranscription elongation factor complex

AFF4 AFF3

1.57e-0356222GO:0008023
HumanPhenoCervical C2/C3 vertebral fusion

AFF4 ASH1L

3.60e-051342HP:0004602
HumanPhenoFibular hypoplasia

AFF4 AFF3

1.38e-042542HP:0003038
HumanPhenoDownturned corners of mouth

AFF4 AFF3 ASH1L

1.75e-0418243HP:0002714
HumanPhenoAplasia/Hypoplasia of the fibula

AFF4 AFF3

2.13e-043142HP:0006492
HumanPhenoSynophrys

AFF4 AFF3 ASH1L

2.15e-0419543HP:0000664
HumanPhenoFacial hypertrichosis

AFF4 AFF3 ASH1L

2.53e-0420643HP:0002219
HumanPhenoFused cervical vertebrae

AFF4 ASH1L

2.73e-043542HP:0002949
HumanPhenoMedial flaring of the eyebrow

AFF4 AFF3 ASH1L

3.42e-0422843HP:0010747
DomainTF_AF4/FMR2

AFF4 AFF3

4.12e-064162IPR007797
DomainAF-4

AFF4 AFF3

4.12e-064162PF05110
DomainIntegrase_cat-core

ERVK-6 NYNRIN

6.87e-065162IPR001584
DomainINTEGRASE

ERVK-6 NYNRIN

6.87e-065162PS50994
DomainRNaseH-like_dom

ERVK-6 NYNRIN

1.56e-0369162IPR012337
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-25 ERVK-9 ERVK-10 ERVK-24

1.49e-159424821542922
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7 ERVK-10 ERVK-24

1.74e-13424410469592
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-25 ERVK-9 ERVK-10 ERVK-24

8.54e-131824518664271
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-19 ERVK-7 ERVK-21

8.71e-13524412629516
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-19 ERVK-21 ERVK-9

8.60e-111224414557543
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-19 ERVK-10

1.15e-0942437983737
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-19 ERVK-9

5.77e-09624315063128
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-19 ERVK-21

3.45e-081024312970426
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

4.56e-0722429460924
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

4.56e-0722429060628
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-9

1.37e-0632429971820
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-19

1.37e-06324210516026
Pubmed

Functional characterization of the AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability.

AFF4 AFF3

1.37e-06324221330300
Pubmed

Impaired conditioned fear and enhanced long-term potentiation in Fmr2 knock-out mice.

AFF4 AFF3

2.74e-06424211923441
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7

4.56e-06524211401426
Pubmed

MLL-AF9 and MLL-ENL alter the dynamic association of transcriptional regulators with genes critical for leukemia.

AFF4 AFF3

4.13e-051424220854876
Pubmed

Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia.

AFF4 AFF3

1.05e-042224216024815
Pubmed

Characterization of the DOT1L network: implications of diverse roles for DOT1L.

AFF4 AFF3

3.68e-044124220431927
Cytoband1q22

ERVK-7 ASH1L

3.77e-04572321q22
Cytoband11p15.4

GVINP1 SBF2

4.50e-0320023211p15.4
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF4 AFF3

1.65e-0641021145
GeneFamilyAF4/FMR2 family|Super elongation complex

AFF4 AFF3

9.89e-0691021280
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4 AFF3

3.12e-05175163d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4 AFF3

3.12e-05175163454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4 AFF3

3.92e-051891632cfb4d12f75678d1619f4743838a0e954bd57761
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4 AFF3

3.92e-05189163127ad2ba3e794df8cce2eee3e4171bccb5aad51b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4 AFF3

4.11e-05192163b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4 AFF3

4.11e-05192163bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4 AFF3

4.24e-051941635c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4 AFF3

4.24e-05194163ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AOAH MGAT5 AFF3

4.24e-05194163c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AOAH MGAT5 AFF3

4.31e-051951637b6c69df943842b566a596e30bb50dbe80dccc83
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

AOAH MGAT5 AFF3

4.37e-05196163cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AOAH MGAT5 AFF3

4.44e-05197163c9b1f2ee7eb31a66af331c5aae29e1bbb5186f5a
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

SBF2 MGAT5 AFF3

4.57e-0519916394b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SBF2 CSPG4

6.58e-04107162c41bc8810df67158f0ae9f6015c965a8ebd96965
ToppCellGlobus_pallidus-Macroglia-POLYDENDROCYTE-P3-Tnr|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

SBF2 CSPG4

6.58e-0410716260b272f5c89bea8a2714f870e18b7ac89a4a4bf6
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)|Thalamus / BrainAtlas - Mouse McCarroll V32

DDX43 CSPG4

6.70e-0410816263d45cc3ee149a7baf255b70409f8ea54c56157b
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P3-Tnr|Thalamus / BrainAtlas - Mouse McCarroll V32

DDX43 CSPG4

6.70e-04108162d57eeda825b6e0e64bae185896ae7eea6a2a50e9
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P3|Thalamus / BrainAtlas - Mouse McCarroll V32

DDX43 CSPG4

6.70e-04108162db8472616886c6195f8c27c00f00133a9c10691d
ToppCellThalamus-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5_(Cspg5)-|Thalamus / BrainAtlas - Mouse McCarroll V32

DDX43 CSPG4

6.70e-04108162c2aa6bf8554bfb6b0f9c5f6658601c6cf7c8bdbc
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAT5 AFF3

6.95e-04110162bc1986e5a496a4d25da3445b6f252f81741619f4
ToppCellfacs-Thymus-Epithelium-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIART MGAT5

6.95e-041101623a641dced828ed97a8eea70d0a7b76f33630c9be
ToppCellfacs-Thymus-Epithelium-3m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIART MGAT5

8.96e-041251626bdbbd47b699d836900bd055f2144cf960b5e7b6
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Ccnb1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DDX43 CSPG4

9.53e-04129162ff74d159034a09f7b174da18bfb9a26936252b4c
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SBF2 CSPG4

1.03e-031341623b67c02b430b6d58467f36e606c478d3eea0063f
ToppCellSevere-B_naive-9|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MGAT5 AFF3

1.11e-03139162b9b049953958f15d773eb5cca6d5dc34f4829543
ToppCellprimary_visual_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DDX43 CSPG4

1.11e-03139162a957ea4e581646c76b16b6a7f89579b8c7ac35b6
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NYNRIN CSPG4

1.17e-0314316227e06327f96cb72bd111ea6ece6307e5ebb3a146
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-hematopoietic_progenitor|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NYNRIN CSPG4

1.17e-031431624edef95ae2a1ef4fc4b0d4fadf75bfc54b583932
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCTR CSPG4

1.19e-03144162121853910eeea1ea0642b3cc99f9200015480368
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c3-CST7|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DDX43 AOAH

1.19e-03144162b638398f559e7fd9d4294d1c830beeb20f905960
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

NYNRIN CSPG4

1.22e-0314616203a6a442f1f6d173a41aeebbfe41ee08853d9585
ToppCellHealthy-B_cell|World / disease group, cell group and cell class

CIART AFF3

1.22e-03146162588359d3df6ad7090b7fa6c7f8d29cc1717e7f4f
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-2|TCGA-Lung / Sample_Type by Project: Shred V9

SEPHS1 TTLL4

1.23e-03147162457bc1175810f241ed8966b76ed4fc4ef3fb144c
ToppCellMild/Remission-B_naive-4|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MGAT5 AFF3

1.25e-03148162dd5e1bc02824e743e1c030a303e32f27a359a8ca
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DDX43 AOAH

1.25e-031481623aa47398cb805c6c6e16b375cc3e9c7f04bb91f4
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SBF2 CSPG4

1.25e-03148162065177aaa63c0441d312260b43ecdac78c84ad03
ToppCellLymphoid-Lymphoid-NK_cells|Lymphoid / shred on cell class and cell subclass (v4)

GVINP1 AOAH

1.25e-03148162d51a4b654a88d58dcdf29c2bc362c0cc1c40723a
ToppCell3'_v3-bone_marrow-Lymphocytic_Invariant-Inducer-like-ILC3|bone_marrow / Manually curated celltypes from each tissue

NYNRIN AFF3

1.27e-03149162d7f1069f70f3cad6d3700ee2041ed1d4cb7c49ab
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DDX43 AOAH

1.32e-03152162ed6df77ba04b715e12c2e1591b4a1e894ca49d25
ToppCellHealthy-B_cell|Healthy / disease group, cell group and cell class

CIART AFF3

1.34e-031531627f82cd61b3f1ebaee3e4bbf68ba858a67c2065e7
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CIART SBF2

1.35e-03154162ba55a63cfa5e0fb9dfec794f80078a2f0d03d0ad
ToppCellnormal_Lung-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

AOAH AFF3

1.35e-03154162835ef49d314ecbcbfd8d1041ba202a5eedcda0bd
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

CYP4X1 NYNRIN

1.39e-031561629a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_C|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CIART AFF3

1.39e-031561626c8f442ed94ae31e6832b68137e98ae78091ac6c
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|356C / Donor, Lineage, Cell class and subclass (all cells)

SBF2 CSPG4

1.39e-031561627ccd20e3bbce6a070df45034b0bdc255f267efb1
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

CYP4X1 LRRIQ1

1.39e-0315616210d191e29b16cae8238e8df6c0ff38882253f34e
ToppCelldroplet-Liver-Npc-21m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL4 AFF3

1.41e-03157162264b22d0ffc43049161843bb55d2eccbf5fca575
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SBF2 CSPG4

1.41e-03157162f2bc60ec0305b056d79f1b7fd6b5e3730d606916
ToppCelldroplet-Liver-Npc-21m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL4 AFF3

1.41e-0315716267945d37027be62c880d3072afa7ca7e97c76c20
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL4 AOAH

1.42e-0315816212661763d1c309106801cb710c04cd2b62d16cba
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL4 AOAH

1.42e-031581620792c39e6fc0745095af7812de2d50949540d60f
ToppCellfacs-Thymus-Thymus_Flowthrough-18m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TTLL4 AOAH

1.42e-03158162e7db50d6dfaf7280a73a0d5b5aa4f43ea2762d72
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CIART CSPG4

1.44e-031591627cda111bb98f1241989e49d490bdf51a712ea589
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Lymphocytic-mature_NK_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX43 AOAH

1.44e-0315916232d4c9f7ba6a96ce8443396b80568b41cbfc4927
ToppCellfacs-SCAT-Fat-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX43 AOAH

1.44e-0315916251bdbacb79227fbee38bb8680c58cb99878df0c7
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AOAH MGAT5

1.50e-031621625731f9514434296132df4bc86f78ce87b07cdeca
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AOAH MGAT5

1.50e-031621620321fc954ae4ad67ca438cbbc84632562d222188
ToppCell10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3|Liver / Manually curated celltypes from each tissue

CSPG4 AFF3

1.51e-031631627f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CYP4X1 CSPG4

1.53e-0316416243630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CYP4X1 CSPG4

1.53e-03164162108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCellfacs-Skin-nan-24m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCTR CSPG4

1.53e-031641627a65c7a6dbe5fb9067f83efafbb7ec8206d79325
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CYP4X1 CSPG4

1.53e-0316416246208f18325976c89f572f6627aea0582142b92d
ToppCellMild-MAIT|World / Disease group and Cell class

NYNRIN AFF3

1.53e-0316416221dc02997dfae73cf70ce291661928526605dba1
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-mature_NK_T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX43 AOAH

1.53e-0316416222f37c39fdce2cf6dc72c6db619537d4b0234839
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4

1.55e-031651629de841c1c95967c562720feba930246debc626fd
ToppCelldroplet-Spleen-SPLEEN-30m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCTR AOAH

1.55e-03165162e24621c8d4dbafb407033d832fe9337f13feae34
ToppCellPBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MGAT5 AFF3

1.55e-03165162fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4

1.55e-03165162a612a7d3a5415ecacc3df8fbff0ce498f982aad0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MGAT5 AFF3

1.55e-031651627039bb5a7af4684fbd1192230864e5cd6936e83c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B-B_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MGAT5 AFF3

1.55e-03165162d2c79653710b139794170f3d72f11392fc548ac7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4

1.55e-03165162cdc94a640ec01c6892521bcd6f0ee0a66ff23866
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX43 AOAH

1.57e-03166162d80c2522cf314d56730d60f160b1247933443378
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX43 AOAH

1.57e-03166162f2593e2f1043a8cedaa677a73e6b28393991b910
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX43 AOAH

1.59e-03167162aef22535a76e93472bcedacbb2c6991f3c9c8cd5
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

MGAT5 AFF3

1.61e-03168162a7159a35fe37f8c241cf8d391debe271e0698105
ToppCellControl-Lymphoid-ILC_B|Lymphoid / Disease state, Lineage and Cell class

MGAT5 AFF3

1.61e-03168162d7118d39253ed9790908b850088ebfc5a86f4065
ToppCell390C-Myeloid-Dendritic-pDC|390C / Donor, Lineage, Cell class and subclass (all cells)

SEPHS1 AFF3

1.61e-031681625a2e7a52b7330dce30823695a7b9b26bc47a69ce
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

MGAT5 AFF3

1.63e-03169162c3a6179a64589a370108fea809b157839347759c
ToppCellIonocyte-iono-1|World / Class top

CIART CSPG4

1.63e-031691624b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCellmetastatic_Brain-B_lymphocytes-GrB-secreting_B_cells|metastatic_Brain / Location, Cell class and cell subclass

SEPHS1 AFF3

1.63e-0316916271f6761b9927f352e0ccc221ca373319915f4184
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4

1.64e-0317016299dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4

1.64e-031701623a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellCiliated_cells-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CYP4X1 LRRIQ1

1.64e-031701628b7ef1464ea589886b575ebad5447b085cbdcdba
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYP4X1 CSPG4

1.64e-03170162d9ed257d0938442d0bb280e4c4b0c9b657511b46
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4

1.64e-03170162cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

MGAT5 AFF3

1.66e-03171162c3e3ea09c73050372314a89b282e36ba5f339d73
ToppCellCOVID-19-kidney-Bcells|COVID-19 / Disease (COVID-19 only), tissue and cell type

MGAT5 AFF3

1.66e-031711628e8fb79968b1a5c34d1d9cad7f9155fabfdb7cc7
ToppCell390C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SEPHS1 AFF3

1.68e-031721623f894c74916d49a995b2d4651ca1c6733c14ce9c
ToppCellmetastatic_Brain-Fibroblasts-Undetermined|Fibroblasts / Location, Cell class and cell subclass

SCTR CIART

1.68e-03172162c3822ff7329c3ac38c68c5c38cd67c390682e2a6
ToppCelldroplet-Lung-3m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l5|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GVINP1 SCTR

1.68e-0317216209c03cc7717373f10e51281be76d53979fcb7ccd
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_naive-B_naive-4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MGAT5 AFF3

1.68e-0317216262ed3b70fa1f6c84ea80ff00f60d2562be292e9d
ToppCelldroplet-Marrow-nan-24m-Hematologic-erythroid_progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SBF2 AFF3

1.68e-03172162910ec7794ea4000db4ef1e2c34e08dbc0243df2c
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SBF2 ASH1L

1.68e-03172162da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR MGAT5

1.68e-031721621565f38266891c3acf49778838de134c5dee5460
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-7|TCGA-Breast / Sample_Type by Project: Shred V9

SEPHS1 TTLL4

1.68e-03172162a2c3b790be85f7fd23f2dc919dcc749656920e71
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CIART CSPG4

1.70e-031731622b448acd5e584f24567204c31b8d74715e92f32a
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4

1.70e-03173162901b8e6909c1f3849906fad9cee17b8f0bab050d
ToppCell3'_v3-bone_marrow-Lymphocytic_B-GC_B_(I)|bone_marrow / Manually curated celltypes from each tissue

SEPHS1 TTLL4

1.70e-0317316267f0f0bf88eab69987b71d96b864ed2b14975adb
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SCTR CSPG4

1.70e-03173162fc2602b2ce051cd4c33957d7e3d041ff8a529883
Diseasemammographic density measurement

GVINP1 AFF3

2.91e-0450152EFO_0005941
Diseaseurate measurement

SBF2 CSPG4 MGAT5 ASH1L

8.78e-04895154EFO_0004531
Diseasetype 2 diabetes mellitus (implicated_via_orthology)

AFF4 AFF3

1.28e-03105152DOID:9352 (implicated_via_orthology)
Diseasetotal blood protein measurement

NYNRIN SBF2 AFF3

1.39e-03449153EFO_0004536
DiseaseS-7-hydroxywarfarin measurement

SBF2 AFF3

1.40e-03110152EFO_0803329
Diseasecholesteryl ester measurement, low density lipoprotein cholesterol measurement

NYNRIN MGAT5

1.83e-03126152EFO_0004611, EFO_0010351
DiseaseFEV/FEC ratio

SBF2 CSPG4 MGAT5 AFF3

2.82e-031228154EFO_0004713
Diseaseserum urea measurement

CSPG4 ASH1L

4.31e-03195152EFO_0009795
Diseaseoptic disc size measurement

MGAT5 LRRIQ1

4.75e-03205152EFO_0004832
Diseaselobe attachment

TTLL4 MGAT5

4.84e-03207152EFO_0007667
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

NYNRIN MGAT5

5.21e-03215152EFO_0008317, EFO_0008591
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

NYNRIN MGAT5

5.45e-03220152EFO_0004529, EFO_0008317
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

NYNRIN MGAT5

5.69e-03225152EFO_0008317, EFO_0010351
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

NYNRIN MGAT5

5.89e-03229152EFO_0004639, EFO_0008317
Diseasecholesteryl ester measurement

NYNRIN SBF2

7.36e-03257152EFO_0010351
Diseasevery low density lipoprotein cholesterol measurement

NYNRIN MGAT5

7.53e-03260152EFO_0008317

Protein segments in the cluster

PeptideGeneStartEntry
WQLDKWLNKVNPHKP

AFF3

466

P51826
ILWQWKHNQLYKKPD

ASH1L

2056

Q9NR48
PQRPSHLWKNKGLWV

CSPG4

1701

Q6UVK1
KEKLLPLQGQLWHHW

GVINP1

1266

Q7Z2Y8
KWQLDNWLNKVNPHK

AFF4

471

Q9UHB7
DHFWKKVQLQWPQIL

AOAH

541

P28039
GHKTPWGKWNLNPQQ

MGAT5

396

Q09328
HKLNQAPEKWQQLWE

SBF2

1651

Q86WG5
SNQLHWPKIPGNLKW

LRRIQ1

1466

Q96JM4
WGLHHNPAVWKNPKV

CYP4X1

411

Q8N118
LKWQKTKWADLPPIK

DDX43

181

Q9NXZ2
GPLHSLLKQKPDWQW

NYNRIN

1116

Q9P2P1
VHQWLDIPEKWNKIK

SEPHS1

211

P49903
ALKPKQPWHLTQWPA

CIART

241

Q8N365
LNQWPKNWPKQKAVT

ERVK-9

36

P63127
LNQWPKNWPKQKAVT

ERVK-24

36

P63129
LNQWPKNWPKQKAVT

HERVK_113

36

P63121
KKWQQWHLREFPLHP

SCTR

401

P47872
LNQWPKNWPKQKAVT

ERVK-7

36

P63131
LNQWPKNWPKQKAVT

ERVK-6

36

Q9Y6I0
LNQWPKNWPKQKAVT

ERVK-25

36

P63125
LNQWPKNWPKQKAVT

ERVK-10

36

P10265
VWPQAHQQVKPIWKL

TTLL4

41

Q14679
LNQWPKNWPKQKAVT

ERVK-21

36

P63119
LNQWPKNWPKQKAVT

HERV-K104

36

P63124
LNQWPKNWPKQKAVT

ERVK-19

36

P63120