Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of skin epidermis

KRT1 KRT2 KRT10

2.62e-0643133GO:0030280
GeneOntologyBiologicalProcesskeratinocyte differentiation

KRT1 KRT2 KRT10 HRNR SRSF6

7.43e-08189135GO:0030216
GeneOntologyBiologicalProcessepidermis development

KRT1 KRT2 KRT10 HRNR COL17A1 SRSF6

1.81e-07461136GO:0008544
GeneOntologyBiologicalProcessepidermal cell differentiation

KRT1 KRT2 KRT10 HRNR SRSF6

5.62e-07284135GO:0009913
GeneOntologyBiologicalProcesspeptide cross-linking

KRT1 KRT2 KRT10

5.67e-0727133GO:0018149
GeneOntologyBiologicalProcessskin development

KRT1 KRT2 KRT10 HRNR SRSF6

2.15e-06373135GO:0043588
GeneOntologyBiologicalProcessregulation of epidermis development

KRT2 KRT10 SRSF6

1.09e-0571133GO:0045682
GeneOntologyBiologicalProcessintermediate filament organization

KRT1 KRT2 KRT10

1.29e-0575133GO:0045109
GeneOntologyBiologicalProcesskeratinization

KRT1 KRT2 HRNR

2.01e-0587133GO:0031424
GeneOntologyBiologicalProcessintermediate filament cytoskeleton organization

KRT1 KRT2 KRT10

2.96e-0599133GO:0045104
GeneOntologyBiologicalProcessintermediate filament-based process

KRT1 KRT2 KRT10

3.05e-05100133GO:0045103
GeneOntologyBiologicalProcessprotein heterotetramerization

KRT1 KRT10

4.38e-0516132GO:0051290
GeneOntologyBiologicalProcesskeratinocyte development

KRT2 KRT10

4.96e-0517132GO:0003334
GeneOntologyBiologicalProcessepithelial cell differentiation

KRT1 KRT2 KRT10 HRNR SRSF6

1.28e-04870135GO:0030855
GeneOntologyBiologicalProcessprotein heterooligomerization

KRT1 KRT10

1.69e-0431132GO:0051291
GeneOntologyBiologicalProcesspositive regulation of epidermis development

KRT2 KRT10

1.91e-0433132GO:0045684
GeneOntologyBiologicalProcessestablishment of skin barrier

KRT1 HRNR

2.97e-0441132GO:0061436
GeneOntologyBiologicalProcesskeratinocyte proliferation

KRT2 SRSF6

8.64e-0470132GO:0043616
GeneOntologyBiologicalProcessepithelium development

KRT1 KRT2 KRT10 HRNR SRSF6

1.44e-031469135GO:0060429
GeneOntologyBiologicalProcessregulation of translational initiation

EIF4H DDX3X

1.45e-0391132GO:0006446
GeneOntologyBiologicalProcessprotein tetramerization

KRT1 KRT10

2.23e-03113132GO:0051262
GeneOntologyBiologicalProcesspositive regulation of canonical Wnt signaling pathway

CSNK1G2 DDX3X

2.55e-03121132GO:0090263
GeneOntologyBiologicalProcessregulation of mRNA splicing, via spliceosome

RBMXL3 SRSF6

2.89e-03129132GO:0048024
GeneOntologyBiologicalProcesstranslational initiation

EIF4H DDX3X

3.03e-03132132GO:0006413
GeneOntologyCellularComponentcornified envelope

KRT1 KRT2 KRT10 HRNR

7.60e-0869134GO:0001533
GeneOntologyCellularComponentkeratin filament

KRT1 KRT2 KRT10

2.68e-0597133GO:0045095
GeneOntologyCellularComponentintermediate filament

KRT1 KRT2 KRT10

3.33e-04227133GO:0005882
GeneOntologyCellularComponentintermediate filament cytoskeleton

KRT1 KRT2 KRT10

5.13e-04263133GO:0045111
GeneOntologyCellularComponentficolin-1-rich granule lumen

KRT1 DDX3X

2.61e-03124132GO:1904813
GeneOntologyCellularComponentcollagen-containing extracellular matrix

KRT1 HRNR COL17A1

3.83e-03530133GO:0062023
GeneOntologyCellularComponentficolin-1-rich granule

KRT1 DDX3X

5.70e-03185132GO:0101002
GeneOntologyCellularComponentextracellular matrix

KRT1 HRNR COL17A1

6.95e-03656133GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

KRT1 HRNR COL17A1

7.01e-03658133GO:0030312
HumanPhenoCongenital bullous ichthyosiform erythroderma

KRT1 KRT2 KRT10

6.35e-09473HP:0007475
HumanPhenoPalmoplantar keratoderma

KRT1 KRT2 KRT10 COL17A1

7.91e-0611474HP:0000982
HumanPhenoAbnormal blistering of the skin

KRT1 KRT2 KRT10 COL17A1

8.19e-0611574HP:0008066
HumanPhenoCongenital ichthyosiform erythroderma

KRT1 KRT2 KRT10

8.52e-063373HP:0007431
HumanPhenoPalmoplantar hyperkeratosis

KRT1 KRT2 KRT10 COL17A1

1.30e-0512974HP:0000972
HumanPhenoPalmar hyperkeratosis

KRT1 KRT2 KRT10 COL17A1

1.38e-0513174HP:0010765
HumanPhenoPlantar hyperkeratosis

KRT1 KRT2 KRT10 COL17A1

1.42e-0513274HP:0007556
HumanPhenoAbnormality of the plantar skin of foot

KRT1 KRT2 KRT10 COL17A1

3.97e-0517174HP:0100872
HumanPhenoConjunctival nodule

KRT1 KRT10

8.85e-051172HP:0009903
HumanPhenoConjunctival hamartoma

KRT1 KRT10

8.85e-051172HP:0100780
HumanPhenoHyperkeratosis

KRT1 KRT2 KRT10 COL17A1

1.34e-0423374HP:0000962
HumanPhenoAbnormality of keratinization

KRT1 KRT2 KRT10 COL17A1

1.60e-0424474HP:0001035
HumanPhenoAbnormal epidermal morphology

KRT1 KRT2 KRT10

2.02e-049473HP:0011124
HumanPhenoRegional abnormality of skin

EIF4H KRT1 KRT2 KRT10 COL17A1

2.32e-0454175HP:0011356
HumanPhenoOrthokeratosis

KRT1 KRT10

3.04e-042072HP:0040162
HumanPhenoHypergranulosis

KRT1 KRT10

3.69e-042272HP:0025114
HumanPhenoBlistering by anatomical location

KRT1 COL17A1

5.18e-042672HP:0033800
HumanPhenoErythema

KRT1 KRT2 KRT10

5.64e-0413373HP:0010783
HumanPhenoSkin erosion

KRT1 KRT10

6.02e-042872HP:0200041
HumanPhenoHamartoma of the orbital region

KRT1 KRT10

6.91e-043072HP:0030670
HumanPhenoHamartoma of the eye

KRT1 KRT10

6.91e-043072HP:0010568
HumanPhenoIchthyosis

KRT1 KRT2 KRT10

7.12e-0414473HP:0008064
HumanPhenoEpidermal thickening

KRT1 KRT2 KRT10 COL17A1

8.81e-0437974HP:0011368
HumanPhenoFragile skin

KRT1 COL17A1

1.05e-033772HP:0001030
HumanPhenoAbnormal skin morphology of the palm

KRT1 KRT2 KRT10 COL17A1

1.22e-0341374HP:0040211
HumanPhenoAbnormal conjunctiva morphology

KRT1 KRT10 COL17A1

1.28e-0317673HP:0000502
HumanPhenoThickened skin

KRT1 KRT2 KRT10 COL17A1

1.44e-0343174HP:0001072
MousePhenohyperkeratosis

KRT1 KRT2 KRT10 COL17A1

1.10e-0690134MP:0001242
MousePhenoblistering

KRT1 KRT10 COL17A1

1.26e-0624133MP:0001208
MousePhenoabnormal epidermis stratum corneum morphology

KRT1 KRT2 KRT10 COL17A1

5.08e-06132134MP:0001240
MousePhenoacanthosis

KRT1 KRT2 KRT10

7.59e-0643133MP:0001874
MousePhenoepidermis stratum spinosum hyperplasia

KRT1 KRT2 KRT10

8.72e-0645133MP:0009611
MousePhenoscaly skin

KRT1 KRT2 KRT10

1.60e-0555133MP:0001192
MousePhenoabnormal epidermis stratum spinosum morphology

KRT1 KRT2 KRT10

2.65e-0565133MP:0001236
MousePhenohypergranulosis

KRT2 KRT10

2.86e-059132MP:0009600
MousePhenoabnormal skin appearance

KRT1 KRT2 KRT10 PLVAP COL17A1

4.46e-05473135MP:0009931
MousePhenothick epidermis stratum granulosum

KRT2 KRT10

5.24e-0512132MP:0009599
MousePhenoabnormal epidermis suprabasal layer morphology

KRT2 KRT10

8.33e-0515132MP:0001233
MousePhenoabnormal epidermal layer morphology

KRT1 KRT2 KRT10 COL17A1

8.60e-05271134MP:0001216
MousePhenoabnormal skin physiology

KRT1 KRT2 KRT10 COL17A1

1.09e-04288134MP:0005501
MousePhenoabnormal corneocyte morphology

KRT1 KRT2

1.21e-0418132MP:0030605
MousePhenoabnormal foot pad morphology

KRT2 KRT10

2.56e-0426132MP:0000574
MousePhenohyperpigmentation

KRT1 KRT2

2.98e-0428132MP:0001188
MousePhenoabnormal skin tensile strength

KRT10 COL17A1

3.90e-0432132MP:0005275
MousePhenosmall testis

KRT1 KRT2 CSNK1G2 DDX3X RBMXL3

6.04e-04823135MP:0001147
MousePhenoincreased vascular permeability

KRT1 PLVAP

8.07e-0446132MP:0003070
MousePhenosmall gonad

KRT1 KRT2 CSNK1G2 DDX3X RBMXL3

8.43e-04885135MP:0001116
MousePhenoabnormal primary sex determination

KRT1 KRT2 CSNK1G2 DDX3X RBMXL3

9.15e-04901135MP:0002211
MousePhenoabnormal testis size

KRT1 KRT2 CSNK1G2 DDX3X RBMXL3

9.82e-04915135MP:0004849
MousePhenoabnormal heart ventricle wall thickness

EIF4H KRT1 PLVAP

1.07e-03227133MP:0020135
MousePhenoabnormal sex determination

KRT1 KRT2 CSNK1G2 DDX3X RBMXL3

1.14e-03945135MP:0002210
MousePhenodecreased circulating serum albumin level

PLVAP HRNR COL17A1

1.23e-03238133MP:0005419
MousePhenoimpaired skin barrier function

KRT1 KRT2

1.56e-0364132MP:0002796
MousePhenoepidermal hyperplasia

KRT2 KRT10

1.71e-0367132MP:0001222
MousePhenoabnormal vascular permeability

KRT1 PLVAP

1.76e-0368132MP:0001619
MousePhenoabnormal epidermis stratum granulosum morphology

KRT2 KRT10

1.86e-0370132MP:0001239
MousePhenoabnormal testis morphology

KRT1 KRT2 CSNK1G2 DDX3X RBMXL3

2.08e-031081135MP:0001146
MousePhenoabnormal heart ventricle wall morphology

EIF4H KRT1 PLVAP

2.30e-03296133MP:0031532
MousePhenothick epidermis

KRT2 COL17A1

2.42e-0380132MP:0001219
MousePhenoabnormal skin pigmentation

KRT1 KRT2

2.86e-0387132MP:0002095
MousePhenoabnormal circulating serum albumin level

PLVAP HRNR COL17A1

3.29e-03336133MP:0000199
DomainIntermediate_filament_CS

KRT1 KRT2 KRT10

1.02e-0563133IPR018039
DomainFilament

KRT1 KRT2 KRT10

1.47e-0571133SM01391
DomainIF

KRT1 KRT2 KRT10

1.53e-0572133PS00226
DomainFilament

KRT1 KRT2 KRT10

1.59e-0573133PF00038
DomainIF

KRT1 KRT2 KRT10

1.80e-0576133IPR001664
DomainKeratin_2_head

KRT1 KRT2

1.22e-0424132PF16208
DomainKeratin_2_head

KRT1 KRT2

1.22e-0424132IPR032444
DomainKeratin_II

KRT1 KRT2

1.44e-0426132IPR003054
DomainRRM_1

EIF4H RBMXL3 SRSF6

3.59e-04208133PF00076
DomainRRM

EIF4H RBMXL3 SRSF6

4.06e-04217133SM00360
DomainKeratin_I

KRT1 KRT10

4.16e-0444132IPR002957
DomainRRM_dom

EIF4H RBMXL3 SRSF6

4.63e-04227133IPR000504
DomainRRM

EIF4H RBMXL3 SRSF6

4.81e-04230133PS50102
Domain-

EIF4H RBMXL3 SRSF6

5.72e-042441333.30.70.330
DomainNucleotide-bd_a/b_plait

EIF4H RBMXL3 SRSF6

6.73e-04258133IPR012677
DomainPrefoldin

KRT1 KRT10

1.11e-0372132IPR009053
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT1 KRT2 KRT10

3.61e-0587113MM15351
PathwayREACTOME_FORMATION_OF_THE_CORNIFIED_ENVELOPE

KRT1 KRT2 KRT10

1.17e-04129113M27649
PathwayREACTOME_KERATINIZATION

KRT1 KRT2 KRT10

1.94e-04153113MM15343
PathwayWP_MRNA_PROCESSING

EIF4H DDX3X RBMXL3 SRSF6

2.85e-04451114MM15946
PathwayREACTOME_DIFFERENTIATION_OF_KERATINOCYTES_IN_INTERFOLLICULAR_EPIDERMIS_IN_MAMMALIAN_SKIN

KRT1 KRT10

4.25e-0440112M48231
PathwayREACTOME_KERATINIZATION

KRT1 KRT2 KRT10

5.42e-04217113M27640
PathwayREACTOME_NEUTROPHIL_DEGRANULATION

KRT1 DDX3X HRNR

5.22e-03478113M27620
PathwayREACTOME_DEVELOPMENTAL_BIOLOGY

KRT1 KRT2 KRT10

5.98e-03502113MM14537
PathwayREACTOME_NEUTROPHIL_DEGRANULATION

KRT1 DDX3X HRNR

6.29e-03511113MM15330
Pubmed

Expanding the Clinical and Genetic Spectrum of KRT1, KRT2 and KRT10 Mutations in Keratinopathic Ichthyosis.

KRT1 KRT2 KRT10

4.08e-11313326581228
Pubmed

Diverse Ras-related GTPase DIRAS2, downregulated by PSMD2 in a proteasome-mediated way, inhibits colorectal cancer proliferation by blocking NF-κB signaling.

KRT1 KRT2 KRT10 HRNR

4.53e-111913435173535
Pubmed

EEF1D Promotes Glioma Proliferation, Migration, and Invasion through EMT and PI3K/Akt Pathway.

KRT1 KRT2 KRT10 DDX3X

7.00e-112113433029523
Pubmed

Interaction of Tumor Necrosis Factor Receptor-associated Factor 6 (TRAF6) and Vav3 in the Receptor Activator of Nuclear Factor κB (RANK) Signaling Complex Enhances Osteoclastogenesis.

KRT1 KRT2 KRT10 DDX3X

1.24e-102413427507811
Pubmed

TRIM25 and DEAD-Box RNA Helicase DDX3X Cooperate to Regulate RIG-I-Mediated Antiviral Immunity.

KRT1 KRT2 KRT10 DDX3X HRNR

1.39e-109113534445801
Pubmed

Serum lipids, retinoic acid and phenol red differentially regulate expression of keratins K1, K10 and K2 in cultured keratinocytes.

KRT1 KRT2 KRT10

1.63e-10413332179842
Pubmed

A Noncanonical Role of Fructose-1, 6-Bisphosphatase 1 Is Essential for Inhibition of Notch1 in Breast Cancer.

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

4.80e-1028613632041737
Pubmed

E3 Ligase Trim21 Ubiquitylates and Stabilizes Keratin 17 to Induce STAT3 Activation in Psoriasis.

KRT1 KRT2 KRT10 HRNR SRSF6

1.03e-0913513529859926
Pubmed

The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

1.13e-0933013632529326
Pubmed

SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

1.69e-0935313627545878
Pubmed

A Mass Spectrometry-Based Profiling of Interactomes of Viral DDB1- and Cullin Ubiquitin Ligase-Binding Proteins Reveals NF-κB Inhibitory Activity of the HIV-2-Encoded Vpx.

KRT1 KRT2 KRT10 DDX3X

1.73e-094513430619335
Pubmed

The proteins elafin, filaggrin, keratin intermediate filaments, loricrin, and small proline-rich proteins 1 and 2 are isodipeptide cross-linked components of the human epidermal cornified cell envelope.

KRT1 KRT2 KRT10

2.28e-0981337543090
Pubmed

The cellular EJC interactome reveals higher-order mRNP structure and an EJC-SR protein nexus.

KRT1 KRT2 KRT10 DDX3X SRSF6

3.18e-0916913523084401
Pubmed

EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma.

KRT1 KRT2 KRT10 HRNR

3.67e-095413435474131
Pubmed

Ephrin-As, Eph receptors and integrin α3 interact and colocalise at membrane protrusions of U251MG glioblastoma cells.

KRT1 KRT2 KRT10 DDX3X HRNR

6.87e-0919713523686814
Pubmed

Direct evidence that involucrin is a major early isopeptide cross-linked component of the keratinocyte cornified cell envelope.

KRT1 KRT2 KRT10

1.16e-08131338999895
Pubmed

Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F.

KRT1 KRT2 KRT10 DDX3X

1.40e-087513431527668
Pubmed

Reactive-site-centric chemoproteomics identifies a distinct class of deubiquitinase enzymes.

KRT1 KRT2 KRT10 HRNR

2.23e-088413429563501
Pubmed

SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

2.59e-0855813627591049
Pubmed

The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation.

KRT1 KRT2 CSNK1G2 KRT10 DDX3X SRSF6

4.14e-0860413637616343
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

4.18e-0860513628977666
Pubmed

Ring finger protein 12 activates AKT signalling to promote the progression of liver cancer by interacting with EGFR.

KRT1 KRT2 KRT10 DDX3X HRNR

4.66e-0828913537132043
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

EIF4H KRT1 KRT10 DDX3X HRNR SRSF6

5.12e-0862613633644029
Pubmed

HDM2-binding partners: interaction with translation elongation factor EF1alpha.

KRT1 KRT2 KRT10

5.40e-082113317373842
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

KRT1 KRT2 KRT10 DDX3X HRNR

5.43e-0829813530737378
Pubmed

The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.

KRT1 KRT2 KRT10 DDX3X HRNR RBMXL3 SRSF6

6.23e-08115313729845934
Pubmed

Prothymosin-α enhances phosphatase and tensin homolog expression and binds with tripartite motif-containing protein 21 to regulate Kelch-like ECH-associated protein 1/nuclear factor erythroid 2-related factor 2 signaling in human bladder cancer.

KRT1 KRT2 KRT10

8.22e-082413330719818
Pubmed

Mutual regulation between OGT and XIAP to control colon cancer cell growth and invasion.

KRT1 KRT2 CSNK1G2 KRT10 DDX3X SRSF6

1.02e-0770413632994395
Pubmed

Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium.

KRT1 KRT2 KRT10

1.06e-072613315454262
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

KRT1 KRT2 KRT10 DDX3X HRNR COL17A1 SRSF6

1.12e-07125713736526897
Pubmed

hnRNPA1 couples nuclear export and translation of specific mRNAs downstream of FGF-2/S6K2 signalling.

KRT1 KRT2 KRT10 DDX3X HRNR

1.14e-0734613525324306
Pubmed

Out of balance: consequences of a partial keratin 10 knockout.

KRT2 KRT10

1.29e-0721329378767
Pubmed

Relationship between the expression of differentiation-specific keratins 1 and 10 and cell proliferation in epidermal tumors.

KRT1 KRT10

1.29e-0721321380247
Pubmed

Keratins K2 and K10 are essential for the epidermal integrity of plantar skin.

KRT2 KRT10

1.29e-07213226603179
Pubmed

New mutations in keratin 1 that cause bullous congenital ichthyosiform erythroderma and keratin 2e that cause ichthyosis bullosa of Siemens.

KRT1 KRT2

1.29e-07213211531804
Pubmed

Human keratin 1/10-1B tetramer structures reveal a knob-pocket mechanism in intermediate filament assembly.

KRT1 KRT10

1.29e-07213231036554
Pubmed

Epidemiology and clinical characteristics of bullous congenital ichthyosiform erythroderma (keratinolytic ichthyosis) in Japan: results from a nationwide survey.

KRT1 KRT10

1.29e-07213223182068
Pubmed

Post Zygotic, Somatic, Deletion in KERATIN 1 V1 Domain Generates Structural Alteration of the K1/K10 Dimer, Producing a Monolateral Palmar Epidermolytic Nevus.

KRT1 KRT10

1.29e-07213234199056
Pubmed

Expanding the keratin mutation database: novel and recurrent mutations and genotype-phenotype correlations in 28 patients with epidermolytic ichthyosis.

KRT1 KRT10

1.29e-07213221271994
Pubmed

In silico predicted structural and functional insights of all missense mutations on 2B domain of K1/K10 causing genodermatoses.

KRT1 KRT10

1.29e-07213227421141
Pubmed

Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation.

KRT2 KRT10

1.29e-07213224751727
Pubmed

Extensive Post-zygotic Mosaicism of KRT1 or KRT10 Mutation Mimicking Classical Epider-molytic Ichthyosis.

KRT1 KRT10

1.29e-07213227722766
Pubmed

Chromosomal mapping of human keratin genes: evidence of non-linkage.

KRT1 KRT10

1.29e-0721322461420
Pubmed

Deletion of K1/K10 does not impair epidermal stratification but affects desmosomal structure and nuclear integrity.

KRT1 KRT10

1.29e-07213222375063
Pubmed

Effect of mutations on the hydrophobic interactions of the hierarchical molecular structure and mechanical properties of epithelial keratin 1/10.

KRT1 KRT10

1.29e-07213235623459
Pubmed

The X-Ray Crystal Structure of the Keratin 1-Keratin 10 Helix 2B Heterodimer Reveals Molecular Surface Properties and Biochemical Insights into Human Skin Disease.

KRT1 KRT10

1.29e-07213227595935
Pubmed

Analysis of KRT1, KRT10, KRT19, TP53 and MMP9 expression in pediatric and adult cholesteatoma.

KRT1 KRT10

1.29e-07213230021014
Pubmed

Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis.

KRT1 KRT10

1.29e-0721321380725
Pubmed

Transgenic mice expressing a mutant keratin 10 gene reveal the likely genetic basis for epidermolytic hyperkeratosis.

KRT1 KRT10

1.29e-0721321379726
Pubmed

Mutations in the rod 1A domain of keratins 1 and 10 in bullous congenital ichthyosiform erythroderma (BCIE).

KRT1 KRT10

1.29e-0721327507152
Pubmed

Genetic mutations in the K1 and K10 genes of patients with epidermolytic hyperkeratosis. Correlation between location and disease severity.

KRT1 KRT10

1.29e-0721327512983
Pubmed

Upregulation of RIN3 induces endosomal dysfunction in Alzheimer's disease.

EIF4H KRT1 KRT2 KRT10 DDX3X

2.91e-0741813532552912
Pubmed

A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.

KRT1 KRT2 KRT10 PLVAP HRNR

2.98e-0742013528065597
Pubmed

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.

KRT1 KRT2 KRT10 DDX3X SRSF6

3.02e-0742113534650049
Pubmed

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.

KRT1 KRT2 KRT10 DDX3X HRNR

3.35e-0743013538172120
Pubmed

Gene targeting at the mouse cytokeratin 10 locus: severe skin fragility and changes of cytokeratin expression in the epidermis.

KRT1 KRT10

3.87e-0731328603923
Pubmed

Effects of extracellular calcium on the growth-differentiation switch in immortalized keratinocyte HaCaT cells compared with normal human keratinocytes.

KRT1 KRT10

3.87e-07313218637039
Pubmed

Ornithine decarboxylase expression in cutaneous papillomas in SENCAR mice is associated with altered expression of keratins 1 and 10.

KRT1 KRT10

3.87e-0731327509717
Pubmed

Transcriptional regulation of Oct4 by a long non-coding RNA antisense to Oct4-pseudogene 5.

KRT1 KRT2 KRT10

4.00e-074013321151833
Pubmed

ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.

KRT1 KRT2 KRT10 DDX3X HRNR

4.24e-0745113536168627
Pubmed

Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.

KRT1 KRT2 KRT10

4.31e-074113334638806
Pubmed

Revealing A-Raf functions through its interactome.

KRT1 KRT2 KRT10 HRNR

5.57e-0718713429777862
Pubmed

PHGDH Inhibits Ferroptosis and Promotes Malignant Progression by Upregulating SLC7A11 in Bladder Cancer.

KRT1 KRT2 KRT10

6.14e-074613336147463
Pubmed

Mouse differentiation-specific keratins 1 and 10 require a preexisting keratin scaffold to form a filament network.

KRT1 KRT10

7.74e-0741327679677
Pubmed

Transcription Factors Runx1 and Runx3 Suppress Keratin Expression in Undifferentiated Keratinocytes.

KRT1 KRT10

7.74e-07413236077435
Pubmed

Complete Structure of an Epithelial Keratin Dimer: Implications for Intermediate Filament Assembly.

KRT1 KRT10

7.74e-07413226181054
Pubmed

A mitochondrial SCF-FBXL4 ubiquitin E3 ligase complex degrades BNIP3 and NIX to restrain mitophagy and prevent mitochondrial disease.

KRT1 KRT2 KRT10

8.41e-075113336896912
Pubmed

A functional reference map of the RNF8 interactome in cancer.

KRT1 KRT2 KRT10 HRNR

1.03e-0621813435831895
Pubmed

FAF1 phosphorylation by AKT accumulates TGF-β type II receptor and drives breast cancer metastasis.

KRT1 KRT2 KRT10 HRNR

1.14e-0622413428443643
Pubmed

RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers.

KRT1 KRT2 KRT10

1.18e-065713331862882
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

1.27e-06108213638697112
Pubmed

Use of monospecific antisera and cRNA probes to localize the major changes in keratin expression during normal and abnormal epidermal differentiation.

KRT1 KRT10

1.29e-0651322458356
Pubmed

The LINC complex transmits integrin-dependent tension to the nuclear lamina and represses epidermal differentiation.

KRT1 KRT10

1.29e-06513233779546
Pubmed

Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma.

KRT1 KRT2 KRT10

1.38e-066013331220272
Pubmed

DDX24 promotes metastasis by regulating RPL5 in non-small cell lung cancer.

KRT1 KRT2 KRT10 HRNR

1.46e-0623813435864588
Pubmed

LukS-PV inhibits hepatocellular carcinoma cells migration by downregulating HDAC6 expression.

KRT1 KRT2 KRT10 DDX3X HRNR

1.46e-0658013535676659
Pubmed

A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity.

KRT1 KRT10 HRNR

1.52e-066213326644517
Pubmed

New consensus nomenclature for mammalian keratins.

KRT1 KRT2 KRT10

1.60e-066313316831889
Pubmed

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.

KRT2 KRT10 DDX3X HRNR

1.63e-0624513435652658
Pubmed

FAM188B enhances cell survival via interaction with USP7.

KRT1 KRT2 KRT10

1.76e-066513329795372
Pubmed

Programming gene expression in developing epidermis.

KRT1 KRT10

1.93e-0661327525178
Pubmed

Development, structure, and keratin expression in C57BL/6J mouse eccrine glands.

KRT1 KRT10

1.93e-06613222135020
Pubmed

Loss of proteolytically processed filaggrin caused by epidermal deletion of Matriptase/MT-SP1.

KRT1 KRT10

1.93e-06613214638864
Pubmed

Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.

KRT1 DDX3X HRNR SRSF6

1.95e-0625613432698014
Pubmed

Charting the molecular network of the drug target Bcr-Abl.

KRT1 KRT2 KRT10 DDX3X

2.27e-0626613419380743
Pubmed

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy.

KRT1 KRT2 KRT10 DDX3X HRNR

2.38e-0664113536057605
Pubmed

DDX39B drives colorectal cancer progression by promoting the stability and nuclear translocation of PKM2.

KRT1 KRT2 KRT10

2.50e-067313335973989
Pubmed

Mouse homologue of skin-specific retroviral-like aspartic protease involved in wrinkle formation.

KRT1 KRT10

2.71e-06713216837463
Pubmed

Regulation of epidermal differentiation by a Distal-less homeodomain gene.

KRT1 KRT10

2.71e-0671328991098
Pubmed

Association between mouse nude gene expression and the initiation of epithelial terminal differentiation.

KRT1 KRT10

2.71e-06713210191051
Pubmed

KAP1 Recruitment of the 7SK snRNP Complex to Promoters Enables Transcription Elongation by RNA Polymerase II.

KRT1 KRT2 HRNR SRSF6

2.82e-0628113426725010
Pubmed

MBD5 and MBD6 stabilize the BAP1 complex and promote BAP1-dependent cancer.

KRT1 KRT2 KRT10 DDX3X

3.06e-0628713436180891
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

KRT1 KRT2 KRT10 DDX3X SRSF6

3.14e-0667813530209976
Pubmed

Comparative analysis of the expression of cytokeratins (1, 10, 14, 16, 4), involucrin, filaggrin and e-cadherin in plane warts and epidermodysplasia verruciformis plane wart-type lesions.

KRT1 KRT10

3.61e-06813219515043
Pubmed

Calmodulin 4 is dispensable for epidermal barrier formation and wound healing in mice.

KRT1 KRT10

3.61e-06813225316000
Pubmed

Induced multipotency in adult keratinocytes through down-regulation of ΔNp63 or DGCR8.

KRT1 KRT10

3.61e-06813224449888
Pubmed

Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.

EIF4H KRT1 KRT2 KRT10 DDX3X

3.85e-0670713519738201
Pubmed

14-3-3sigma controls mitotic translation to facilitate cytokinesis.

KRT1 KRT2 KRT10

4.10e-068613317361185
Pubmed

Prohibitin 1 regulates tumor cell apoptosis via the interaction with X-linked inhibitor of apoptosis protein.

KRT1 KRT2 KRT10 DDX3X SRSF6

4.35e-0672513527025967
Pubmed

Aurora kinase-A deficiency during skin development impairs cell division and stratification.

KRT1 KRT10

4.64e-06913222832491
InteractionEFNA1 interactions

KRT1 KRT2 KRT10 DDX3X HRNR

3.94e-09103135int:EFNA1
InteractionKRT17 interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

5.74e-09252136int:KRT17
InteractionDIRAS2 interactions

KRT1 KRT2 KRT10 HRNR

2.77e-0852134int:DIRAS2
InteractionFBP1 interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

3.93e-08348136int:FBP1
InteractionNDN interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

1.87e-07453136int:NDN
InteractionKRT77 interactions

KRT1 KRT2 KRT10 DDX3X

3.34e-0796134int:KRT77
InteractionMAGOH interactions

KRT1 KRT2 KRT10 DDX3X SRSF6

4.39e-07264135int:MAGOH
InteractionEFNA3 interactions

KRT1 KRT2 KRT10 HRNR

5.37e-07108134int:EFNA3
InteractionMETTL3 interactions

KRT1 KRT2 KRT10 DDX3X HRNR

6.63e-07287135int:METTL3
InteractionCUL2 interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

8.93e-07591136int:CUL2
InteractionPIGR interactions

KRT1 KRT2 KRT10 DDX3X

1.24e-06133134int:PIGR
InteractionMIDN interactions

KRT1 KRT2 CSNK1G2 KRT10 DDX3X SRSF6

1.25e-06626136int:MIDN
InteractionTNF interactions

KRT1 KRT2 KRT10 DDX3X SRSF6

1.53e-06340135int:TNF
InteractionARL4D interactions

KRT1 KRT2 KRT10 HRNR

1.80e-06146134int:ARL4D
InteractionLARP7 interactions

KRT1 KRT2 KRT10 DDX3X HRNR RBMXL3 SRSF6

1.97e-061113137int:LARP7
InteractionNPHP3 interactions

KRT1 KRT2 KRT10

2.37e-0642133int:NPHP3
InteractionRLIM interactions

KRT1 KRT2 KRT10 DDX3X HRNR

3.07e-06392135int:RLIM
InteractionRNF31 interactions

KRT1 KRT2 KRT10 DDX3X HRNR

3.52e-06403135int:RNF31
InteractionZUP1 interactions

KRT1 KRT2 KRT10 HRNR

3.61e-06174134int:ZUP1
InteractionCHD3 interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

3.77e-06757136int:CHD3
InteractionKRT10 interactions

KRT1 KRT2 KRT10 DDX3X

4.81e-06187134int:KRT10
InteractionBTF3 interactions

EIF4H KRT1 KRT10 DDX3X HRNR SRSF6

5.15e-06799136int:BTF3
InteractionKRT5 interactions

KRT1 KRT2 KRT10 DDX3X

5.45e-06193134int:KRT5
InteractionWTAP interactions

KRT1 KRT2 KRT10 HRNR

5.56e-06194134int:WTAP
InteractionSMAD3 interactions

KRT2 CSNK1G2 KRT10 DDX3X DNAJB5

5.83e-06447135int:SMAD3
InteractionKRT16 interactions

KRT1 KRT2 KRT10 DDX3X

5.91e-06197134int:KRT16
InteractionTRIM31 interactions

KRT1 KRT2 KRT10 DDX3X SRSF6

6.29e-06454135int:TRIM31
InteractionPRPH interactions

EIF4H KRT1 KRT2 KRT10

6.79e-06204134int:PRPH
InteractionRIN3 interactions

EIF4H KRT1 KRT2 KRT10 DDX3X

6.92e-06463135int:RIN3
InteractionMEPCE interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

7.82e-06859136int:MEPCE
InteractionINPPL1 interactions

KRT1 KRT2 KRT10 DDX3X

8.20e-06214134int:INPPL1
InteractionCYLD interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

8.30e-06868136int:CYLD
InteractionARHGAP24 interactions

KRT1 KRT2 KRT10 DDX3X HRNR

8.76e-06486135int:ARHGAP24
InteractionEIF4A3 interactions

KRT1 KRT2 KRT10 DDX3X SRSF6

9.96e-06499135int:EIF4A3
InteractionPIK3R2 interactions

KRT1 KRT2 KRT10 DDX3X

1.09e-05230134int:PIK3R2
InteractionARF5 interactions

KRT1 KRT2 KRT10 HRNR

1.11e-05231134int:ARF5
InteractionHEXIM1 interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

1.11e-05913136int:HEXIM1
InteractionKRT2 interactions

KRT1 KRT2 KRT10 DDX3X

1.21e-05236134int:KRT2
InteractionKRT1 interactions

KRT1 KRT2 KRT10 DDX3X

1.25e-05238134int:KRT1
InteractionMINDY4 interactions

KRT1 KRT2 KRT10

1.27e-0573133int:MINDY4
InteractionPRSS1 interactions

KRT1 KRT2 KRT10

1.27e-0573133int:PRSS1
InteractionCHD4 interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

1.30e-05938136int:CHD4
InteractionHNRNPA1 interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

1.35e-05945136int:HNRNPA1
InteractionRNF208 interactions

KRT1 KRT2 KRT10

1.38e-0575133int:RNF208
InteractionOGT interactions

KRT1 KRT2 CSNK1G2 KRT10 DDX3X SRSF6

1.39e-05950136int:OGT
InteractionPAGE4 interactions

KRT1 DDX3X HRNR SRSF6

1.59e-05253134int:PAGE4
InteractionKRT7 interactions

KRT1 KRT2 KRT10

1.67e-0580133int:KRT7
InteractionMETTL14 interactions

KRT1 KRT2 KRT10 HRNR SRSF6

1.71e-05558135int:METTL14
InteractionRPS6KB2 interactions

KRT1 KRT2 KRT10 DDX3X

1.79e-05261134int:RPS6KB2
InteractionAHI1 interactions

KRT1 KRT2 KRT10

1.87e-0583133int:AHI1
InteractionARL16 interactions

KRT1 KRT2 KRT10

1.87e-0583133int:ARL16
InteractionDCUN1D1 interactions

KRT1 KRT2 KRT10 DDX3X

2.20e-05275134int:DCUN1D1
InteractionDDX24 interactions

KRT1 KRT2 KRT10 HRNR SRSF6

2.35e-05596135int:DDX24
InteractionEIF3F interactions

KRT1 KRT2 KRT10 DDX3X

2.94e-05296134int:EIF3F
InteractionINVS interactions

KRT1 KRT2 KRT10

3.17e-0599133int:INVS
InteractionCOPS5 interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

3.25e-051102136int:COPS5
InteractionACE2 interactions

EIF4H KRT1 KRT2 KRT10 DDX3X HRNR

3.31e-051106136int:ACE2
InteractionCFAP57 interactions

KRT1 KRT10

3.48e-0514132int:CFAP57
InteractionDDX3X interactions

KRT1 KRT2 KRT10 DDX3X HRNR

3.59e-05651135int:DDX3X
InteractionARIH2 interactions

KRT1 KRT2 KRT10 DDX3X

3.70e-05314134int:ARIH2
InteractionFBXL4 interactions

KRT1 KRT2 KRT10

3.89e-05106133int:FBXL4
InteractionEVPL interactions

KRT1 KRT2 KRT10

3.89e-05106133int:EVPL
InteractionRC3H2 interactions

KRT1 KRT2 KRT10 DDX3X SRSF6

4.04e-05667135int:RC3H2
InteractionRC3H1 interactions

KRT1 KRT2 KRT10 DDX3X SRSF6

4.33e-05677135int:RC3H1
InteractionEEF1D interactions

KRT1 KRT2 KRT10 DDX3X

4.65e-05333134int:EEF1D
InteractionFAF1 interactions

KRT1 KRT2 KRT10 HRNR

4.71e-05334134int:FAF1
InteractionKRT13 interactions

KRT1 KRT2 DDX3X

5.10e-05116133int:KRT13
InteractionCUL4B interactions

KRT1 KRT2 KRT10 DDX3X RBMXL3

6.13e-05728135int:CUL4B
InteractionIQCB1 interactions

KRT1 KRT2 KRT10 HRNR

7.01e-05370134int:IQCB1
InteractionCRK interactions

KRT1 KRT2 KRT10 DDX3X

7.01e-05370134int:CRK
InteractionNPHP1 interactions

KRT1 KRT2 KRT10

7.15e-05130133int:NPHP1
InteractionARAF interactions

KRT1 KRT2 KRT10 HRNR

7.46e-05376134int:ARAF
InteractionMECP2 interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

7.79e-051287136int:MECP2
InteractionMKS1 interactions

KRT1 KRT2 KRT10

8.73e-05139133int:MKS1
InteractionNEDD8 interactions

KRT1 KRT2 KRT10 DDX3X

8.86e-05393134int:NEDD8
InteractionPAN2 interactions

KRT1 KRT2 KRT10 SRSF6

9.21e-05397134int:PAN2
InteractionCOPS6 interactions

KRT1 KRT2 KRT10 DDX3X

1.02e-04408134int:COPS6
InteractionMYCN interactions

KRT1 KRT2 KRT10 DDX3X HRNR SRSF6

1.12e-041373136int:MYCN
InteractionKRT18 interactions

KRT1 KRT2 KRT10 COL17A1

1.13e-04419134int:KRT18
InteractionRNF8 interactions

KRT1 KRT2 KRT10 HRNR

1.16e-04421134int:RNF8
InteractionDSP interactions

KRT1 DDX3X HRNR COL17A1

1.18e-04423134int:DSP
InteractionUBASH3B interactions

KRT1 KRT2 KRT10

1.25e-04157133int:UBASH3B
InteractionAP2M1 interactions

KRT1 KRT2 KRT10 DDX3X

1.25e-04430134int:AP2M1
InteractionFN1 interactions

EIF4H KRT1 KRT2 KRT10 DDX3X

1.26e-04848135int:FN1
InteractionDES interactions

KRT1 KRT2 KRT10

1.28e-04158133int:DES
InteractionKRT6A interactions

KRT2 KRT10 DDX3X

1.32e-04160133int:KRT6A
InteractionHDAC2 interactions

KRT1 KRT2 KRT10 DDX3X HRNR

1.39e-04865135int:HDAC2
InteractionASXL3 interactions

KRT1 KRT2 KRT10

1.45e-04165133int:ASXL3
InteractionCUL1 interactions

KRT1 KRT2 KRT10 DDX3X SRSF6

1.47e-04876135int:CUL1
InteractionCAND1 interactions

KRT1 KRT2 KRT10 DDX3X SRSF6

1.62e-04894135int:CAND1
InteractionKRT28 interactions

KRT1 KRT2

1.65e-0430132int:KRT28
InteractionTRAF6 interactions

KRT1 KRT2 KRT10 DDX3X

1.70e-04465134int:TRAF6
InteractionEWSR1 interactions

EIF4H KRT2 DDX3X HRNR SRSF6

1.73e-04906135int:EWSR1
InteractionVCAM1 interactions

KRT1 KRT2 KRT10 DDX3X

1.84e-04475134int:VCAM1
InteractionKRT75 interactions

KRT1 KRT2 KRT10

1.91e-04181133int:KRT75
InteractionHDAC6 interactions

KRT1 KRT2 KRT10 DDX3X HRNR

1.94e-04929135int:HDAC6
InteractionTHRB interactions

KRT1 KRT2 KRT10

2.07e-04186133int:THRB
InteractionARL10 interactions

KRT1 KRT10 HRNR

2.17e-04189133int:ARL10
InteractionTNIP2 interactions

EIF4H KRT1 KRT10 DDX3X SRSF6

2.18e-04952135int:TNIP2
InteractionKRT25 interactions

KRT1 KRT2

2.26e-0435132int:KRT25
Cytoband12q13.13

KRT1 KRT2

1.62e-046713212q13.13
CytobandEnsembl 112 genes in cytogenetic band chr12q13

KRT1 KRT2

6.18e-03423132chr12q13
GeneFamilyKeratins, type II

KRT1 KRT2

1.17e-0427112609
GeneFamilyRNA binding motif containing

EIF4H RBMXL3 SRSF6

2.48e-04213113725
CoexpressionMURAKAMI_UV_RESPONSE_1HR_UP

KRT1 KRT10

2.38e-0515132M13308
CoexpressionMURAKAMI_UV_RESPONSE_24HR

KRT1 KRT10

4.29e-0520132M17175
CoexpressionAZARE_STAT3_TARGETS

DDX3X SRSF6

6.23e-0524132M2312
CoexpressionHOLLERN_SQUAMOUS_BREAST_TUMOR

KRT1 KRT10 HRNR

7.70e-05173133M650
CoexpressionGSE40666_WT_VS_STAT4_KO_CD8_TCELL_UP

KRT2 PLVAP COL17A1

9.54e-05186133M9228
CoexpressionGSE17186_MEMORY_VS_CD21LOW_TRANSITIONAL_BCELL_DN

PITPNM2 CSNK1G2 KRT10

1.17e-04199133M7183
CoexpressionGSE19401_NAIVE_VS_IMMUNIZED_MOUSE_PLN_FOLLICULAR_DC_UP

EIF4H KRT10 DNAJB5

1.17e-04199133M7656
CoexpressionGSE27670_CTRL_VS_BLIMP1_TRANSDUCED_GC_BCELL_UP

KRT1 KRT10 COL17A1

1.18e-04200133M8212
CoexpressionGSE8685_IL2_STARVED_VS_IL21_ACT_IL2_STARVED_CD4_TCELL_UP

EIF4H DDX3X SRSF6

1.18e-04200133M328
CoexpressionHOLLERN_SQUAMOUS_BREAST_TUMOR

KRT1 KRT10 HRNR

1.25e-04204133MM966
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

KRT2 DDX3X PLVAP

1.98e-04238133M2020
CoexpressionJAEGER_METASTASIS_DN

KRT1 KRT10 COL17A1

2.56e-04260133M10702
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3_UNMETHYLATED

KRT2 DDX3X PLVAP

2.59e-04261133MM1277
CoexpressionJARDIM_PERASSI_TRIPLE_NEGATIVE_BREAST_CANCER_MOUSE_XENOGRAFT_MELATONIN_UP

KRT1 HRNR

2.64e-0449132MM452
CoexpressionBRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D

KRT2 DDX3X PLVAP

3.15e-04279133M2246
CoexpressionBRUINS_UVC_RESPONSE_VIA_TP53_GROUP_D

KRT2 DDX3X PLVAP

3.64e-04293133MM895
CoexpressionPUJANA_ATM_PCC_NETWORK

EIF4H KRT2 CSNK1G2 DDX3X SRSF6

3.80e-041394135M9585
CoexpressionGOTTWEIN_TARGETS_OF_KSHV_MIR_K12_11

PITPNM2 CSNK1G2

4.36e-0463132M18201
CoexpressionAtlasMyeloid Cells, DC.LC.Sk, MHCII+ CD11b+ CD45+, Skin, avg-2

KRT1 KRT2 KRT10 COL17A1

8.68e-05451124GSM538280_500
CoexpressionAtlasDevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#3_top-relative-expression-ranked_500

KRT1 KRT10

8.72e-0525122gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_500_k3
CoexpressionAtlasskin

KRT1 KRT2 KRT10 COL17A1

9.06e-05456124skin
ToppCellSkin|World / Skin and Kidney Cells in Lupus Nephritis Patients.

KRT1 KRT2 KRT10 COL17A1

2.57e-071991346be1340413ee868c610b6e3f58c65b493eb22bb5
ToppCellKidney-Keratinocytes|Kidney / Skin and Kidney Cells in Lupus Nephritis Patients.

KRT1 KRT2 KRT10 COL17A1

2.63e-0720013441d83faa9f45ee7ea2ab19be8ecc6d2c5ac7fe5d
ToppCellSkin-Keratinocytes|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

KRT1 KRT2 KRT10 DDX3X

2.63e-0720013459d72395199bc30df0e811fbc99149694e208860
ToppCelldroplet-Skin|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10 COL17A1

1.90e-05185133657fd191ed160f8620d57b33820ec7222806f289
ToppCellTCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6|TCGA-Skin / Sample_Type by Project: Shred V9

KRT1 KRT10 COL17A1

1.96e-051871332ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCellTCGA-Skin-Primary_Tumor|TCGA-Skin / Sample_Type by Project: Shred V9

KRT1 KRT10 COL17A1

2.06e-05190133e2b26a03c6ab24d9b0f4150c47597be37767d86e
ToppCellTCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

KRT1 KRT10 COL17A1

2.06e-051901333188c7bd225cbcf46a21e2fb784336cdd9665995
ToppCellTCGA-Skin-Primary_Tumor-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

KRT1 KRT10 COL17A1

2.06e-0519013301fb45add4661bc86cd0a34fac35177907152dbb
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr-Excitatory_Neuron.Slc17a7.Nptxr-Fos_(Deep_layer_pyramidal_cells_(IEG))|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

KRT2 COL17A1

1.69e-0467132b17d498034ab8280be4991cca1527373d7e43f38
ToppCellPosterior_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Ctps_(Ctps)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

HRNR COL17A1

3.04e-04901324d75217fd6b376bfda3300962cbe4875b31ffdaf
ToppCellPND07-28-samps-Myeloid-Macrophage-macrophage-A|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PITPNM2 KRT1

4.71e-04112132d21cfcb04a27cc9fb74e0c2afa8a8cdfb886ae21
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KRT1 KRT2

5.49e-041211327f2057367777c6c92f596054cbc5fe567d079fbc
ToppCelldroplet-Skin-nan-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

6.33e-041301324c8b931987432e8bcd39029d4fa124dc383ea355
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KRT1 KRT2

6.33e-0413013260e28d452d0e2af768459ba8dbe998117c94a251
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Krt73|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

KRT1 KRT2

6.43e-041311329ca209a8652aae603c4a867ea06b06ac51e7d189
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-Mast-Mast-D|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KRT1 HRNR

6.92e-0413613294eb78a4b8da307c07c2c4f05b8a14424f887579
ToppCellfacs-Skin-Anagen-24m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

7.23e-04139132da8874d441b8e69c94bad771635f378ddafb49fe
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid-late_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

KRT1 PLVAP

7.75e-04144132ca365380ccf5e60d2e3f6272059ff0531759612d
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

8.30e-04149132d259e9137109eeb2662022f0915ca463f5bebdfe
ToppCellPSB-critical-LOC-Lymphoid-NKT|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

PITPNM2 PLVAP

8.74e-041531324d45aa5e3710d5badc13940f14095c1894dbab9d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP COL17A1

9.32e-041581320c3907e3395ed01b3fd7b75fdca6feadc890ea85
ToppCell5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-ILC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KRT1 KRT2

9.67e-04161132a3318e738836eb1c5babe1a5d2dd7fa34d732662
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PLVAP DNAJB5

1.03e-031661329d4b44eb56ad38c26aed73444edf389abca6bdf6
ToppCell10x3'2.3-week_14-16-Hematopoietic-erythroid-late_erythroid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

KRT1 HRNR

1.03e-03166132b4e5466a33578103d197cf67f37e7ec88e09281f
ToppCellfacs-Skin-Anagen-24m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.04e-0316713202c89069dcd0e87f7502e32b14e7cbd3cab81a09
ToppCellCOVID-19-Myeloid-MoAM5,_CCL3L1|Myeloid / Condition, Lineage and Cell class

PLVAP DNAJB5

1.05e-03168132ea465152ea31391b63c02425beafa9a4f51f6703
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.06e-031691327be742160e3e7e6c8f86b037be4e425f4d4cf663
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_PP_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.06e-031691324ccf5cfa4fe72d3af056d658460a9ccaa07b01be
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8|TCGA-Liver / Sample_Type by Project: Shred V9

PITPNM2 PLVAP

1.09e-03171132c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCellfacs-Skin-nan-24m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.10e-031721325ca89af7406e7e1a055dd60d6f89615f69e62324
ToppCellTCGA-Head_and_Esophagus|World / Sample_Type by Project: Shred V9

KRT1 COL17A1

1.10e-03172132eb18aa179db1818f408c38e442ecfed8582d7dbc
ToppCellwk_15-18-Hematologic-Myeloid-Mast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KRT1 KRT2

1.10e-03172132a7146c255031207e64682ef767884b11c96e0d59
ToppCellwk_20-22-Hematologic-Meg-ery-Definitive_erythrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

KRT1 PLVAP

1.10e-03172132f0b658baa4b41329c95a09387cc55ea046e2333f
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.12e-031731320f9c1d3298e59e6d22bb3306f0f445f490be8bbd
ToppCellnormal-na-Hematopoietic-Progen-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

KRT2 COL17A1

1.12e-03173132e666364eb110c1c976e5b09a632dd1454513f131
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

PITPNM2 PLVAP

1.13e-03174132b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PITPNM2 KRT2

1.14e-0317513226bd957498e41a3f1ffa60d3effa27ca8c4ba631
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DDX3X PLVAP

1.14e-03175132282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF4H PLVAP

1.14e-03175132b4ff5a74ad22addbdd848dde9ba93d63a0611543
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EIF4H PLVAP

1.14e-0317513227a8c6e398638ccdee90c44e2ca6f59acc206cbc
ToppCelldroplet-Liver-LIVER-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP COL17A1

1.15e-031761324880fa20b50eb10358e08567e08559ef2954f237
ToppCelldroplet-Liver-LIVER-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP COL17A1

1.15e-03176132fcdddd949ca05b3ecde240db9e38296a6eab2d6a
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP DNAJB5

1.15e-0317613288ca2f83d8301633232735f39b0683efe49d0b86
ToppCellfacs-Marrow-KLS-18m-Lymphocytic-early_pro_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP DNAJB5

1.15e-031761327292e014b8f697f0c2e9f47c48333de95cb44a69
ToppCellHippocampus|World / BrainAtlas - Mouse McCarroll V32

EIF4H KRT2

1.15e-03176132f120a703f6d2f2d5f55eae1aea2e6382a485828f
ToppCellwk_15-18-Hematologic-Meg-ery-Definitive_erythrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

KRT1 PLVAP

1.15e-031761329af82b976e6a14a3ef7aa50f1f7af2463e5aa5d2
ToppCelldroplet-Liver-LIVER-30m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP COL17A1

1.15e-031761324d2fb51e71bed0d72f3d7f89d395744860885a5f
ToppCell356C-Endothelial_cells-Endothelial-D|356C / Donor, Lineage, Cell class and subclass (all cells)

PLVAP COL17A1

1.17e-03177132a0b172f40e0df97a288a5549ae7066697ad469b3
ToppCell356C-Endothelial_cells-Endothelial-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

PLVAP COL17A1

1.17e-03177132ab8f09e118e4df696b0b4d33f013da020bdbd351
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PITPNM2 PLVAP

1.18e-03178132375156ba1c7b8592bf733c75f24968161f7cfa09
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PITPNM2 PLVAP

1.18e-031781326bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCellMultiple_Sclerosis-Other-RBC|Multiple_Sclerosis / Disease, Lineage and Cell Type

KRT1 PLVAP

1.19e-0317913215763dc59ee6186416e203ffbb450ae4608eba59
ToppCellfacs-Skin-Anagen-3m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.19e-031791324a072526c3a524a7aed99bdb32a07a1ce1f48972
ToppCelldroplet-Limb_Muscle-Pre-Sort|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX3X PLVAP

1.21e-03180132af2bafcd1b2082629de3ea336711add01565c4c4
ToppCellCOVID-19-kidney-PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNM2 PLVAP

1.21e-03180132493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DDX3X PLVAP

1.21e-03180132f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.22e-031811320756d7d315b8cdd07a3cf6cdfc8a0679786b8e6a
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.22e-031811323f0d88e9506d66d4e71b88c50d5187302065930f
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.22e-03181132b09947d2d7b21f96d98b87ceb6f467ea329c4092
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PITPNM2 KRT1

1.23e-03182132f5f42e23832d0210560009ce6fd8eee89751e252
ToppCellfacs-Skin-Telogen-3m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.25e-03183132ed1e0b07475f9951728682ed70b85367cf2a744d
ToppCellfacs-Skin-Telogen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.25e-0318313226b18d1cc5d98f185176e100bafb9bc9081c66f7
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PITPNM2 PLVAP

1.26e-0318413297e97de52daaff8840f4ee76a94ba5e3f79de7ce
ToppCellfacs-Skin-nan-18m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.26e-03184132dc7f6ee4062856a02423fff8b1cce62d46a9355c
ToppCellILEUM-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

DDX3X SRSF6

1.26e-03184132cef3ee2a4a0af961aa3b4c92150d423e841ae8c1
ToppCellLPS-IL1RA|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITPNM2 DDX3X

1.26e-03184132c066c2ec4f0f1d6eb183fca5c7bb0cd45c9950dc
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PLVAP HRNR

1.27e-031851320ab1be455f2cd883c9d1522ca78112c37833352e
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNM2 PLVAP

1.27e-03185132673308ca0514a4d3629d61fe91e9d8fb31b72166
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP COL17A1

1.29e-031861322cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCellIIF-Other-RBC|IIF / Disease, Lineage and Cell Type

KRT1 PLVAP

1.29e-03186132db3c3fc2045c657b300b640bf228640c30782509
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.29e-031861320cc7504297fd0c97ea50e4b3ff58fcedc4c1cfaa
ToppCellPCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.29e-031861322cbf1aaff87cd9fba01f814a119fe86e5af82290
ToppCellfacs-Skin-Anagen-3m-Epithelial-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.29e-031861329a7932d0a208f3997216bd21a72913cc82b59fc9
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP COL17A1

1.29e-0318613290d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-erythrocytic|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KRT1 PLVAP

1.30e-0318713213023661c26aaf9e42262a4ff91f2fb26e8a3eaf
ToppCellSmart-seq2-blood_(Smart-seq2)-hematologic-erythrocytic-erythrocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KRT1 PLVAP

1.30e-03187132c4ba9dfedbcf0357a8627af03f4fe1770e985a03
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KRT1 PLVAP

1.31e-03188132da211e7fb62fff176aa9c39061aef9ab0af6079e
ToppCellPCW_13-14-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.31e-03188132986aaf31161ec3d1e6c76ee2dd17f44848a21f7e
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.31e-03188132b294d6658e79328bd6fa33223e8c70117ba9789b
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic-erythrocytic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KRT1 PLVAP

1.31e-031881323467149de45b47a5015486ef94bec070e9c3ffc2
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.31e-03188132b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCell10x_3'_v3-blood_(10x_3'_v3)-hematologic|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KRT1 PLVAP

1.31e-031881323c6c0eaadc474ebb218ae349b787c410f66177ab
ToppCelldroplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLVAP COL17A1

1.33e-03189132ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCellPCW_10-12-Endothelial-Endothelial_mature-endo_bronchial_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.33e-03189132033a2be8bbb7bfb437e6f1657b6ca02070c74aa8
ToppCellPCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.34e-031901329a2244c3973aee7270646bf00db7727edb9decc5
ToppCellCOVID-19-Endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

PITPNM2 PLVAP

1.34e-031901329fbd92cd6d4683b2490504d29c43cf42020433d4
ToppCellCOVID-19-Endothelial_cells-Endothelial_cells_(general)|COVID-19 / group, cell type (main and fine annotations)

PITPNM2 PLVAP

1.34e-03190132812e11314c76c0179fbe5a9bea29b41ce5cbc93d
ToppCelldroplet-Skin-nan-21m-Epithelial-epidermal_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 KRT10

1.36e-03191132c5ef34d138cd797029dfefaf4c52d16ba6a76c38
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNM2 PLVAP

1.36e-031911322f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCellfacs-Skin|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT10 COL17A1

1.36e-03191132ae524103331fa53fa82888dbb567fc36abcee7e0
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating2_(14)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.37e-03192132ac3d87aa301d30515c369bd7fc16f33b82173a85
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

PITPNM2 PLVAP

1.37e-0319213227ff3621e177e7932dd44dd6baa81551ea75a874
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature2_(1)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.37e-03192132f68e6cbde87678122da1b5c0061904cfb7d04bf5
ToppCellfacs-Spleen-nan-18m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KRT1 COL17A1

1.37e-031921321f81b356520b5506051383d37fae204d59795336
ToppCellPCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.38e-03193132643f992dbce639e7d147924d8b8f455fcebf215a
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.38e-0319313272d20ee257149b238016b44d183ce3fc24b8f621
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.38e-031931322661ad9107ed9231e4afea4442a79051139a31df
ToppCellPCW_05-06-Endothelial-Endothelial_cycling-endo_proliferating3_(3)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.38e-03193132f7e4a390921780587b9bd084e495e646fa1ec74f
ToppCellPCW_07-8.5-Endothelial-Endothelial_cycling-endo_proliferating3_(3)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

PITPNM2 PLVAP

1.38e-0319313272128ece598070f8e752a0691e024e26ab364989
ToppCellCOVID-19-Endothelial_cells-Inflamed_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

PITPNM2 PLVAP

1.38e-03193132979ebefa527f86bebeea5d94e626ee6c1cc7d53b
ComputationalNeighborhood of DDX5

CSNK1G2 DDX3X SRSF6

1.57e-056393GNF2_DDX5
ComputationalKeratin.

KRT1 KRT2

2.00e-042692MODULE_298
ComputationalGenes in the cancer module 68.

KRT1 KRT2

2.00e-042692MODULE_68
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

KRT1 KRT10

7.48e-045092GAVISH_3CA_METAPROGRAM_EPITHELIAL_EPISEN
ComputationalGenes in the cancer module 322.

KRT1 KRT2

1.04e-035992MODULE_322
ComputationalIntermediate filaments.

KRT1 COL17A1

1.68e-037592MODULE_154
ComputationalGenes in the cancer module 297.

KRT1 COL17A1

1.90e-038092MODULE_297
ComputationalIntermediate filaments and keratins.

KRT1 COL17A1

1.90e-038092MODULE_357
Drugbeta-damascenone

KRT1 KRT10 HRNR

2.92e-0724133ctd:C075388
DrugCH2Cl

KRT1 KRT10 COL17A1

4.72e-0728133CID005378701
DrugAC1L9MJT

KRT1 KRT2 KRT10 COL17A1

3.30e-06192134CID000448959
DrugCarbinoxamine maleate salt [3505-38-2]; Up 200; 9.8uM; HL60; HT_HG-U133A

KRT1 DDX3X COL17A1 DNAJB5

3.73e-061981342725_UP
DrugChromates

KRT1 KRT10

1.08e-059132ctd:D002840
DrugAC1O517G

KRT1 KRT10

3.60e-0516132CID006450188
DrugK-11

KRT1 KRT10

4.07e-0517132CID000469667
Drugteleocidin B

KRT1 KRT2 KRT10

4.23e-05123133CID000072425
Drugdithranol

KRT2 KRT10

4.58e-0518132CID000002202
Drugbromovanin

KRT2 KRT10 DDX3X

4.65e-05127133ctd:C515564
Drugsulfur mustard

KRT1 KRT2 KRT10

4.99e-05130133CID000010461
Drughomocysteine thiolactone

KRT1 KRT2 KRT10

5.10e-05131133CID000107712
Drugdichloromethyl

KRT1 KRT10

5.68e-0520132CID000123193
Drugdisoxaril

KRT1 PLVAP

7.56e-0523132CID000055717
Drugal-Badry

KRT1 KRT2 KRT10

1.01e-04165133CID000004545
DrugBi-E

KRT1 KRT10

1.05e-0427132CID006914595
Drug[(2R,3R,4R,5S,6R)-2-[[[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-hydroxyphosphoryl]oxy-5-hydroxy-6-(hydroxymethyl)-3-[(2-tritioacetyl)amino]oxan-4-yl] (3R)-3-hydroxydecanoate

KRT1 KRT10

1.13e-0428132CID011650719
DrugAC1NQZM2

KRT1 KRT10

1.21e-0429132CID005282177
DrugK-13

KRT1 KRT10

1.39e-0431132CID000469669
DrugGW0742

KRT1 KRT10

1.39e-0431132ctd:C479979
Drugmucidin

KRT10 PLVAP

1.48e-0432132CID006437379
DrugAC1NBTRA

KRT1 PLVAP

1.48e-0432132CID004473609
Drugradicicol; Up 200; 0.1uM; PC3; HG-U133A

KRT1 KRT10 DNAJB5

1.66e-04195133449_UP
DrugMetampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; PC3; HT_HG-U133A

DDX3X PLVAP DNAJB5

1.66e-041951335115_UP
Drugalpha-estradiol; Up 200; 0.01uM; HL60; HT_HG-U133A

DDX3X PLVAP DNAJB5

1.69e-041961332670_UP
Drugrofecoxib; Down 200; 10uM; HL60; HG-U133A

KRT1 PLVAP DNAJB5

1.71e-04197133371_DN
DrugEucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; PC3; HT_HG-U133A

KRT2 COL17A1 DNAJB5

1.74e-041981334316_UP
Drugtazarotene

KRT2 KRT10

2.32e-0440132CID000005381
DrugN-(N-(3,5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester

KRT1 KRT10

2.81e-0444132ctd:C419410
DrugD-glucamine

KRT10 COL17A1

2.94e-0445132CID000027282
Drugd-indobufen

KRT1 COL17A1

3.63e-0450132CID000044562
DrugCKI-7

CSNK1G2 KRT10

4.08e-0453132CID000129236
Drugcignolin

KRT2 KRT10

4.55e-0456132CID000010187
DrugAC1L9INI

KRT10 COL17A1

5.06e-0459132CID000445839
Drug1-2q

KRT1 KRT2 KRT10

5.27e-04289133CID000011820
DrugTG-2

KRT10 COL17A1

5.76e-0463132CID000574319
Drugalitretinoin

KRT1 KRT10 COL17A1

5.93e-04301133ctd:C103303
Drug9-cis-acitretin

KRT2 KRT10

7.31e-0471132CID000041317
Drug5-Acetamido-5,6-Dihydro-4-Hydroxy-6-Isobutoxy-4h-Pyran-2-Carboxylic Acid

KRT2 COL17A1

7.73e-0473132CID011963505
Drug4-oxoretinoic acid

KRT1 KRT10

8.60e-0477132CID006437063
Drug1pxm

KRT1 KRT10

8.82e-0478132CID000447959
Drugfullerene C60

CSNK1G2 DDX3X PLVAP DNAJB5 SRSF6

1.01e-031498135ctd:C069837
DrugVelcade (bortezomib

KRT1 KRT2 KRT10

1.11e-03374133CID000093860
Drug4-hydroxyproline

PLVAP COL17A1

1.20e-0391132CID000000825
DrugAC1MHEDK

PITPNM2 KRT1

1.28e-0394132CID003002889
DrugAC1L1GT5

KRT1 KRT10

1.30e-0395132CID000003829
Drugmicrocystin RR

KRT2 KRT10

1.33e-0396132ctd:C063855
Drugadenosine 3',5'-cyclic phosphate

KRT1 KRT2 CSNK1G2 KRT10

1.34e-03907134CID000000274
DiseaseCongenital reticular ichthyosiform erythroderma

KRT1 KRT10

1.52e-072122C3665704
DiseaseIchthyosis, Cyclic, with Epidermolytic Hyperkeratosis

KRT1 KRT10

1.52e-072122C1843463
DiseaseEpidermolytic ichthyosis

KRT1 KRT10

1.52e-072122cv:C0079153
DiseaseErythrokeratoderma, Reticular

KRT1 KRT10

1.52e-072122C1836681
DiseaseAnnular epidermolytic ichthyosis

KRT1 KRT10

1.52e-072122cv:C1843463
Diseaseepidermolytic hyperkeratosis (is_implicated_in)

KRT1 KRT10

1.52e-072122DOID:4603 (is_implicated_in)
Diseasecinnamaldehyde measurement

KRT1 KRT2

1.52e-072122EFO_0021839
Diseaseepidermolytic hyperkeratosis (implicated_via_orthology)

KRT1 KRT10

4.55e-073122DOID:4603 (implicated_via_orthology)
DiseaseHyperkeratosis, Epidermolytic

KRT1 KRT10

1.52e-065122C0079153
DiseaseKeratoderma, Palmoplantar

KRT1 KRT10

1.81e-0516122C4551675
DiseaseMalignant neoplasm of skin

KRT1 KRT10

2.56e-0459122C0007114
DiseaseSkin Neoplasms

KRT1 KRT10

2.56e-0459122C0037286
DiseaseContact hypersensitivity

KRT2 KRT10

3.71e-0471122C0162351
DiseaseContact Dermatitis

KRT2 KRT10

3.71e-0471122C0011616
DiseaseSquamous cell carcinoma

KRT1 KRT10

1.12e-03124122C0007137
Diseasesphingomyelin measurement

KRT1 KRT2

5.48e-03278122EFO_0010118
Diseasechildhood onset asthma

PITPNM2 HRNR

7.82e-03334122MONDO_0005405

Protein segments in the cluster

PeptideGeneStartEntry
TADIHSYGSSGGGGS

COL17A1

421

Q9UMD9
GGTSGGSSGSFHYTF

DNAJB5

76

O75953
SRASSSRSGGGGHGS

DDX3X

616

O00571
AYSSFGGGRGSRGSA

EIF4H

11

Q15056
SSSKHYSSSRSGGGG

KRT10

6

P13645
GYGGGSSSGGHKSSS

KRT10

556

P13645
SSSYGSGGRQSGSRG

KRT2

536

P35908
AGGGRSSHGIRSSGT

CSNK1G2

21

P78368
EHGGSYARAGGSSRG

PLVAP

6

Q9BX97
SSRSGYRSGGGFSSG

KRT1

6

P04264
AGSSSSYGQHGSGSR

HRNR

511

Q86YZ3
GRSSSRGPYESGSGH

HRNR

566

Q86YZ3
RGSGSGQSPSYGRHG

HRNR

896

Q86YZ3
GQSPSYGRHGSGSGR

HRNR

901

Q86YZ3
YGRHGSGSGRSSSSG

HRNR

906

Q86YZ3
SGSGRSSSSGRHGSG

HRNR

911

Q86YZ3
RGRHGSGSGQSSSYG

HRNR

1011

Q86YZ3
YGRHGSGSGRSSSSG

HRNR

1141

Q86YZ3
HGSGSGRSSSRGPYE

HRNR

1261

Q86YZ3
YGHRGSGSSQSSGYG

HRNR

1336

Q86YZ3
SGSSQSSGYGRHGAG

HRNR

1341

Q86YZ3
SRGRHGSGSGHSSSY

HRNR

1361

Q86YZ3
RGRHGSGSGQSSSYS

HRNR

1481

Q86YZ3
YGRHGSGSGRSSSSG

HRNR

1611

Q86YZ3
HGSGSGRSSSRGPYE

HRNR

1731

Q86YZ3
SRGRHGSGSGHSSSY

HRNR

1831

Q86YZ3
RGRHGSGSGQSSSYG

HRNR

1951

Q86YZ3
YGRHGSGSGRSSSSG

HRNR

2081

Q86YZ3
GERHGSSSGSSSRYG

HRNR

2146

Q86YZ3
HGSGSGRSSSRGPYE

HRNR

2201

Q86YZ3
SRGRHGSGSGHSSSY

HRNR

2301

Q86YZ3
RGRHGSGSGQSSSYS

HRNR

2421

Q86YZ3
YGRHGSGSGRSSSSG

HRNR

2551

Q86YZ3
HGSGSGRSSSRGPYE

HRNR

2671

Q86YZ3
YGHRGSGSSQSSGYG

HRNR

2746

Q86YZ3
SGSSQSSGYGRHGAG

HRNR

2751

Q86YZ3
GGGSSGGSSLESSRH

PITPNM2

626

Q9BZ72
SGGGGYSSRRTSGRD

SRSF6

86

Q13247
SGGRSPDAYSGGHDS

RBMXL3

681

Q8N7X1