Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

FBN1 FN1 AEBP1 LAMA1 CRELD2 FBN3

1.14e-05188546GO:0005201
GeneOntologyMolecularFunctionpre-mRNA 3'-splice site binding

U2AF1 U2AF1L4

1.49e-047542GO:0030628
GeneOntologyCellularComponentextracellular matrix

WNT5B CELA3A FBN1 FCGBP FN1 AEBP1 LAMA1 LAMC3 FBN3

4.89e-05656559GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

WNT5B CELA3A FBN1 FCGBP FN1 AEBP1 LAMA1 LAMC3 FBN3

5.00e-05658559GO:0030312
GeneOntologyCellularComponentU2AF complex

U2AF1 U2AF1L4

1.42e-047552GO:0089701
GeneOntologyCellularComponentbasement membrane

FBN1 FN1 LAMA1 LAMC3

2.99e-04122554GO:0005604
GeneOntologyCellularComponentcollagen-containing extracellular matrix

WNT5B CELA3A FBN1 FN1 AEBP1 LAMA1 LAMC3

4.58e-04530557GO:0062023
GeneOntologyCellularComponentmicrofibril

FBN1 FBN3

5.20e-0413552GO:0001527
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN8A

9.01e-0417552GO:0001518
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN8A

1.25e-0320552GO:0033268
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN8A

2.64e-0329552GO:0043194
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN8A

2.64e-0329552GO:0034706
HumanPhenoSudden unexpected death in epilepsy

WWOX SCN1A SCN8A

7.12e-0610213HP:0033258
HumanPhenoFocal automatism seizure

SCN1A SCN8A LAMC3

1.30e-0512213HP:0032898
DomainEGF

FBN1 FCGBP EGF LAMA1 CRELD2 LAMC3 MEGF11 FBN3 NOTCH2 ADGRL4 STAB1

7.28e-112355511SM00181
DomainEGF-like_dom

FBN1 FCGBP EGF LAMA1 CRELD2 LAMC3 MEGF11 FBN3 NOTCH2 ADGRL4 STAB1

1.35e-102495511IPR000742
DomainEGF-like_CS

FBN1 EGF FN1 LAMA1 CRELD2 LAMC3 MEGF11 FBN3 NOTCH2 ADGRL4 STAB1

2.23e-102615511IPR013032
DomainEGF_1

FBN1 EGF FN1 LAMA1 CRELD2 LAMC3 MEGF11 FBN3 NOTCH2 STAB1

3.22e-092555510PS00022
DomainEGF_2

FBN1 EGF LAMA1 CRELD2 LAMC3 MEGF11 FBN3 NOTCH2 ADGRL4 STAB1

4.66e-092655510PS01186
DomainGrowth_fac_rcpt_

FBN1 EGF LAMA1 CRELD2 LAMC3 FBN3 NOTCH2 STAB1

1.73e-08156558IPR009030
DomainEGF_CA

FBN1 EGF CRELD2 FBN3 NOTCH2 ADGRL4 STAB1

6.68e-08122557SM00179
DomainEGF-like_Ca-bd_dom

FBN1 EGF CRELD2 FBN3 NOTCH2 ADGRL4 STAB1

7.47e-08124557IPR001881
DomainLaminin_EGF

LAMA1 CRELD2 LAMC3 MEGF11 STAB1

8.57e-0838555IPR002049
DomainEGF_CA

FBN1 EGF CRELD2 FBN3 NOTCH2 ADGRL4

1.93e-0786556PF07645
DomainEGF_Ca-bd_CS

FBN1 EGF CRELD2 FBN3 NOTCH2 ADGRL4

3.96e-0797556IPR018097
DomainEGF_3

FBN1 EGF CRELD2 MEGF11 FBN3 NOTCH2 ADGRL4 STAB1

4.08e-07235558PS50026
DomainEGF_CA

FBN1 EGF CRELD2 FBN3 NOTCH2 ADGRL4

4.47e-0799556PS01187
DomainASX_HYDROXYL

FBN1 EGF CRELD2 FBN3 NOTCH2 ADGRL4

4.75e-07100556PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

FBN1 EGF CRELD2 FBN3 NOTCH2 ADGRL4

6.70e-07106556IPR000152
DomainLaminin_EGF

LAMA1 LAMC3 MEGF11 STAB1

3.29e-0635554PF00053
DomainEGF_Lam

LAMA1 LAMC3 MEGF11 STAB1

3.29e-0635554SM00180
Domain-

EGF ADGRL4 STAB1

3.92e-06115532.40.155.10
DomainGFP-like

EGF ADGRL4 STAB1

3.92e-0611553IPR023413
DomainFBN

FBN1 FBN3

2.55e-053552IPR011398
DomainhEGF

MEGF11 FBN3 NOTCH2

7.51e-0528553PF12661
DomainU2AF_small

U2AF1 U2AF1L4

8.47e-055552IPR009145
DomainEGF_LAM_2

LAMA1 LAMC3 STAB1

9.27e-0530553PS50027
DomainEGF_LAM_1

LAMA1 LAMC3 STAB1

9.27e-0530553PS01248
DomainNa_trans_cytopl

SCN1A SCN8A

1.27e-046552PF11933
DomainNa_trans_cytopl

SCN1A SCN8A

1.27e-046552IPR024583
DomainGalactose-bd-like

PTPRK AEBP1 LAMA1 LAMC3

1.69e-0494554IPR008979
DomainZnf_A20

ZFAND6 ZFAND5

1.77e-047552IPR002653
DomainTB

FBN1 FBN3

1.77e-047552PF00683
DomainZF_A20

ZFAND6 ZFAND5

1.77e-047552PS51036
Domainzf-A20

ZFAND6 ZFAND5

1.77e-047552PF01754
DomainZnF_A20

ZFAND6 ZFAND5

1.77e-047552SM00259
Domain-

ZFAND6 ZFAND5

2.36e-0485524.10.1110.10
Domainzf-AN1

ZFAND6 ZFAND5

2.36e-048552PF01428
DomainZF_AN1

ZFAND6 ZFAND5

2.36e-048552PS51039
DomainLAMININ_IVA

LAMA1 LAMC3

2.36e-048552PS51115
DomainLaminin_B

LAMA1 LAMC3

2.36e-048552PF00052
Domain-

FBN1 FBN3

2.36e-0485523.90.290.10
DomainLamB

LAMA1 LAMC3

2.36e-048552SM00281
DomainZnf_AN1

ZFAND6 ZFAND5

2.36e-048552IPR000058
DomainZnF_AN1

ZFAND6 ZFAND5

2.36e-048552SM00154
DomainLaminin_IV

LAMA1 LAMC3

2.36e-048552IPR000034
DomainTB

FBN1 FBN3

3.02e-049552PS51364
DomainTB_dom

FBN1 FBN3

3.02e-049552IPR017878
DomainNa_channel_asu

SCN1A SCN8A

3.77e-0410552IPR001696
DomainNa_trans_assoc

SCN1A SCN8A

3.77e-0410552IPR010526
DomainNa_trans_assoc

SCN1A SCN8A

3.77e-0410552PF06512
DomainEGF

EGF FBN3 NOTCH2 STAB1

5.16e-04126554PF00008
DomainLaminin_N

LAMA1 LAMC3

9.95e-0416552IPR008211
DomainLAMININ_NTER

LAMA1 LAMC3

9.95e-0416552PS51117
DomainLaminin_N

LAMA1 LAMC3

9.95e-0416552PF00055
DomainLamNT

LAMA1 LAMC3

9.95e-0416552SM00136
DomaincEGF

FBN1 FBN3

2.64e-0326552IPR026823
DomaincEGF

FBN1 FBN3

2.64e-0326552PF12662
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

FN1 LAMA1 LAMC3

8.78e-0530413M27772
PathwayREACTOME_MOLECULES_ASSOCIATED_WITH_ELASTIC_FIBRES

FBN1 FN1 FBN3

1.66e-0437413M27134
PathwayWP_FOCAL_ADHESION

EGF FN1 LAMA1 LAMC3 ITGAX

1.98e-04187415MM15913
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

FBN1 FN1 LAMA1 LAMC3 ITGAX FBN3

2.12e-04300416M610
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

FN1 LAMA1 LAMC3

2.25e-0441413M27778
PathwayREACTOME_ELASTIC_FIBRE_FORMATION

FBN1 FN1 FBN3

2.78e-0444413M26969
PathwayPID_A6B1_A6B4_INTEGRIN_PATHWAY

EGF LAMA1 LAMC3

3.18e-0446413M239
PathwayKEGG_PATHWAYS_IN_CANCER

WNT5B MSH6 EGF FN1 LAMA1 LAMC3

3.26e-04325416M12868
PathwayWP_CANCER_PATHWAYS

WNT5B MSH6 EGF FN1 LAMA1 LAMC3 NOTCH2

5.80e-04507417M48302
PathwayWP_MAMMARY_GLAND_DEVELOPMENT_PUBERTY_STAGE_2_OF_4

EGF FN1

6.31e-0413412M39582
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

FN1 LAMA1 LAMC3

6.63e-0459413M27218
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

FBN1 EGF ZNF423

6.63e-0459413M39886
PathwayPID_INTEGRIN1_PATHWAY

FBN1 FN1 LAMA1

9.20e-0466413M18
Pubmed

Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.

FBN1 FN1 FBN3

1.50e-08455325034023
Pubmed

Distribution of fibronectin, type I collagen, type IV collagen, and laminin in the cardiac jelly of the mouse embryonic heart with retinoic acid-induced complete transposition of the great arteries.

FBN1 FN1 LAMA1

4.46e-07105539415455
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

2.46e-06255237901435
Pubmed

Fibrillin assembly requires fibronectin.

FBN1 FN1

2.46e-06255219037100
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

2.46e-06255226410685
Pubmed

Further delineation of familial polycystic ovary syndrome (PCOS) via whole-exome sequencing: PCOS-related rare FBN3 and FN1 gene variants are identified.

FN1 FBN3

2.46e-06255235141985
Pubmed

FN1-EGF gene fusions are recurrent in calcifying aponeurotic fibroma.

EGF FN1

2.46e-06255226691015
Pubmed

Stabilin-1 mediates beneficial monocyte recruitment and tolerogenic macrophage programming during CVB3-induced viral myocarditis.

FN1 STAB1

2.46e-06255234968453
Pubmed

Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients.

FBN1 FBN3

2.46e-06255215221638
Pubmed

Selective integrin subunit reduction disrupts fibronectin extracellular matrix deposition and fibrillin 1 gene expression.

FBN1 FN1

2.46e-06255222782528
Pubmed

Mycobacterium tuberculosis malate synthase is a laminin-binding adhesin.

FN1 LAMA1

2.46e-06255216677310
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

2.46e-06255233411788
Pubmed

Fibrillin-1 microfibril deposition is dependent on fibronectin assembly.

FBN1 FN1

2.46e-06255218653538
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

2.46e-06255231943325
Pubmed

The zinc finger domains in U2AF26 and U2AF35 have diverse functionalities including a role in controlling translation.

U2AF1 U2AF1L4

2.46e-06255232116123
Pubmed

Complex contributions of fibronectin to initiation and maturation of microfibrils.

FBN1 FN1

2.46e-06255224070235
Pubmed

Remodeling of extracellular matrix by normal and tumor-associated fibroblasts promotes cervical cancer progression.

FN1 LAMA1

2.46e-06255225885552
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

2.46e-06255237665666
Pubmed

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

SCN1A SCN8A

2.46e-06255217881658
Pubmed

Protein interactome reveals converging molecular pathways among autism disorders.

FBN1 FN1 ZNF423 CRELD2 MEGF11 NOTCH2 OPLAH STAB1

2.69e-0656055821653829
Pubmed

Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.

FN1 LAMA1 LAMC3

3.00e-061855311311202
Pubmed

ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells.

FBN1 FN1 LAMA1

3.00e-061855339040056
Pubmed

Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation.

SLC12A1 LAMA1 NOTCH2

3.00e-061855329113990
Pubmed

Mapping of the mouse fibronectin gene (Fn-1) to chromosome 1: conservation of the Idh-1-Cryg-Fn-1 synteny group in mammals.

FN1 AOX1

7.36e-0635522895729
Pubmed

EGF-mediated migration signaling activated by N-acetylglucosaminyltransferase-V via receptor protein tyrosine phosphatase kappa.

EGF PTPRK

7.36e-06355219236842
Pubmed

IGFBP-3 can either inhibit or enhance EGF-mediated growth of breast epithelial cells dependent upon the presence of fibronectin.

EGF FN1

7.36e-06355220851879
Pubmed

The extracellular matrix is a novel attribute of endothelial progenitors and of hypoxic mature endothelial cells.

FN1 LAMA1

7.36e-06355222919069
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN8A

7.36e-06355232845893
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN8A

7.36e-06355228518218
Pubmed

Identification of EGF-NF-κB-FOXC1 signaling axis in basal-like breast cancer.

EGF FOXC1

7.36e-06355228629477
Pubmed

Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.

SCN1A SCN8A

7.36e-06355224704313
Pubmed

Characterization of U2AF(6), a splicing factor related to U2AF(35).

U2AF1 U2AF1L4

7.36e-06355211739736
Pubmed

The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels.

SCN1A SCN8A

7.36e-06355228117367
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN8A

7.36e-06355217928448
Pubmed

Molecular structure and interaction of recombinant human type XVI collagen.

FBN1 FN1

7.36e-06355215165854
Pubmed

Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.

SCN1A SCN8A

7.36e-06355226182346
Pubmed

De novo SCN1A, SCN8A, and CLCN2 mutations in childhood absence epilepsy.

SCN1A SCN8A

7.36e-06355231054517
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

CELA3A FBN1 FN1 LAMA1 CRELD2

8.64e-0617555528071719
Pubmed

Adamts18 modulates the development of the aortic arch and common carotid artery.

FBN1 FN1 LAMA1

9.48e-062655334189436
Pubmed

Endothelial Loss of ETS1 Impairs Coronary Vascular Development and Leads to Ventricular Non-Compaction.

FBN1 FN1 LAMA1

1.07e-052755335894043
Pubmed

Comprehensive proteomic characterization of stem cell-derived extracellular matrices.

WNT5B FBN1 FN1 AEBP1

1.08e-058655428327460
Pubmed

Serum amyloid p component does not circulate in complex with C4-binding protein, fibronectin or any other major protein ligand.

FN1 ITGAX

1.47e-05455212100475
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN8A

1.47e-05455217537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN8A

1.47e-05455235031483
Pubmed

Expression of CD 73 (ecto-5'-nucleotidase) in 165 glioblastomas by immunohistochemistry and electronmicroscopic histochemistry.

FN1 LAMA1

1.47e-05455210470109
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN8A

1.47e-05455229578003
Pubmed

Immunolocalization of microfibril and microfibril-associated proteins in the subendothelial matrix of the developing mouse aorta.

FBN1 FN1

1.47e-0545528006086
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN8A

1.47e-05455221156207
Pubmed

The extracellular matrix proteins laminin and fibronectin contain binding domains for human plasminogen and tissue plasminogen activator.

FN1 LAMA1

1.47e-0545528360181
Pubmed

Models for discovery of targeted therapy in genetic epileptic encephalopathies.

SCN1A SCN8A

1.47e-05455228742937
Pubmed

Epidermal growth factor and tumor necrosis factor α cooperatively promote the motility of hepatocellular carcinoma cell lines via synergistic induction of fibronectin by NF-κB/p65.

EGF FN1

1.47e-05455228844984
Pubmed

The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes.

FN1 LAMA1

2.45e-05555228092265
Pubmed

Genetic mapping of the absence of third molars in EL mice to chromosome 3.

EGF NOTCH2

2.45e-05555214514757
Pubmed

Immunohistochemical localization of Pax2 and associated proteins in the developing kidney of mice with renal hypoplasia.

FN1 LAMA1

2.45e-05555211511678
Pubmed

Interactions of the amino-terminal noncollagenous (NC1) domain of type VII collagen with extracellular matrix components. A potential role in epidermal-dermal adherence in human skin.

FN1 LAMA1

2.45e-0555529169408
Pubmed

Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice.

FBN1 FN1 LAMA1

2.80e-053755334323105
Pubmed

Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.

FN1 LAMA1

3.67e-05655228348210
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN8A

3.67e-05655223652591
Pubmed

Insights into the structure and dynamics of lysyl oxidase propeptide, a flexible protein with numerous partners.

EGF FN1

3.67e-05655230082873
Pubmed

Biochemical dissection of Anosmin-1 interaction with FGFR1 and components of the extracellular matrix.

FN1 LAMA1

3.67e-05655220874775
Pubmed

A role for PDGF-C/PDGFRα signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex.

FN1 LAMA1

5.13e-05755226988758
Pubmed

Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells.

FBN1 FN1

5.13e-05755221778429
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN8A

5.13e-05755225818041
Pubmed

Mapping of mouse gamma crystallin genes on chromosome 1.

FN1 AOX1

5.13e-0575523242494
Pubmed

Tyrosine-phosphorylated and nonphosphorylated sodium channel beta1 subunits are differentially localized in cardiac myocytes.

SCN1A SCN8A

5.13e-05755215272007
Pubmed

Putative functions of extracellular matrix glycoproteins in secondary palate morphogenesis.

FBN1 FN1

6.83e-05855223055981
Pubmed

A cytokine network involving IL-36γ, IL-23, and IL-22 promotes antimicrobial defense and recovery from intestinal barrier damage.

IL36G NOTCH2

6.83e-05855229760082
Pubmed

Beta1 integrins are required for the invasion of the caecum and proximal hindgut by enteric neural crest cells.

FN1 LAMA1

6.83e-05855219633172
Pubmed

Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment.

FN1 LAMA1

6.83e-05855219651211
Pubmed

Comparative proteomic analysis of supportive and unsupportive extracellular matrix substrates for human embryonic stem cell maintenance.

FBN1 FN1 LAMA1

6.96e-055055323658023
Pubmed

Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins.

FN1 LAMA1

8.78e-0595529827803
Pubmed

Expression of laminin alpha1, alpha2, alpha4, and alpha5 chains, fibronectin, and tenascin-C in skeletal muscle of dystrophic 129ReJ dy/dy mice.

FN1 LAMA1

8.78e-0595529882526
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN8A

8.78e-05955216382098
Pubmed

Detection of gelatinolytic activity in developing basement membranes of the mouse embryo head by combining sensitive in situ zymography with immunolabeling.

FN1 LAMA1

8.78e-05955222688677
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN8A

8.78e-05955215746173
Pubmed

Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.

FBN1 FN1

8.78e-05955238844137
Pubmed

Sodium channel Scn1b null mice exhibit prolonged QT and RR intervals.

SCN1A SCN8A

8.78e-05955217884088
Pubmed

Limb- and tendon-specific Adamtsl2 deletion identifies a role for ADAMTSL2 in tendon growth in a mouse model for geleophysic dysplasia.

FBN1 FN1

1.10e-041055230738849
Pubmed

Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.

LAMA1 LAMC3

1.10e-041055211784026
Pubmed

SOX17 links gut endoderm morphogenesis and germ layer segregation.

FN1 LAMA1

1.10e-041055225419850
Pubmed

Primary cellular meningeal defects cause neocortical dysplasia and dyslamination.

LAMA1 FOXC1

1.10e-041055220976766
Pubmed

Regional differences in the expression of laminin isoforms during mouse neural tube development.

LAMA1 LAMC3

1.34e-041155221524702
Pubmed

Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.

LAMA1 LAMC3

1.34e-041155223472759
Pubmed

Notch signaling promotes nephrogenesis by downregulating Six2.

SLC12A1 NOTCH2

1.60e-041255227633993
Pubmed

Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation.

FN1 FOXC1

1.60e-041255215342473
Pubmed

Matrilin-2 interacts with itself and with other extracellular matrix proteins.

FN1 LAMA1

1.60e-041255212180907
Pubmed

Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart.

FOXC1 STAB1

1.60e-041255218296617
Pubmed

Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation.

FBN1 FN1

1.60e-041255226405179
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN8A

1.60e-041255230175250
Pubmed

Basal lamina molecules are concentrated in myogenic regions of the mouse limb bud.

FN1 LAMA1

1.89e-04135529833687
Pubmed

Mapping anti-müllerian hormone (Amh) and related sequences in the mouse: identification of a new region of homology between MMU10 and HSA19p.

FN1 AOX1

1.89e-04135521685136
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN8A

1.89e-041355215123669
Pubmed

Searching QTL by gene expression: analysis of diabesity.

CELA3A FN1 AOX1

1.98e-047155315760467
Pubmed

Loss of Gli3 and Shh function disrupts olfactory axon trajectories.

FN1 LAMA1

2.21e-041455215065125
Pubmed

The first draft of the endostatin interaction network.

FN1 LAMA1

2.21e-041455219542224
Pubmed

Defining brain wiring patterns and mechanisms through gene trapping in mice.

PTPRK LAMA1

2.21e-041455211242070
Pubmed

Molecular determinants of epithelial mesenchymal transition in mouse placenta and trophoblast stem cell.

WNT5B FN1

2.21e-041455237414855
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

WWOX DHCR7 EIF5 NOTCH2

2.42e-0419155431177093
Pubmed

Basement membrane composition in the early mouse embryo day 7.

LAMA1 LAMC3

2.54e-041555215895400
Pubmed

α5 and αv integrins cooperate to regulate vascular smooth muscle and neural crest functions in vivo.

FBN1 FN1

2.54e-041555225670798
Cytoband7p13

AEBP1 NPC1L1

1.01e-03395527p13
CytobandEnsembl 112 genes in cytogenetic band chr7p13

AEBP1 NPC1L1

1.87e-0353552chr7p13
Cytoband1p36.21

PLEKHM2 SLC25A34

2.63e-03635521p36.21
GeneFamilyZinc fingers AN1-type|UPF1 like RNA helicases

ZFAND6 ZFAND5

1.07e-04836263
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN8A

1.38e-0493621203
GeneFamilyLaminin subunits

LAMA1 LAMC3

2.51e-0412362626
GeneFamilyKelch like|BTB domain containing

KLHL23 KLHL26

3.16e-0342362617
GeneFamilySolute carriers

SLC12A1 SLC25A34 MTCH2 SLC27A5

7.61e-03395364752
CoexpressionNABA_ECM_GLYCOPROTEINS

FBN1 FN1 AEBP1 LAMA1 CRELD2 LAMC3 FBN3

1.76e-07196557M3008
CoexpressionNABA_MATRISOME

WNT5B CELA3A FBN1 EGF FN1 AEBP1 LAMA1 CRELD2 LAMC3 IL36G MEGF11 FBN3

1.12e-0610265512M5889
CoexpressionNABA_CORE_MATRISOME

FBN1 FN1 AEBP1 LAMA1 CRELD2 LAMC3 FBN3

1.71e-06275557M5884
CoexpressionNABA_ECM_GLYCOPROTEINS

FBN1 FN1 AEBP1 LAMA1 CRELD2 LAMC3

2.98e-06191556MM17059
CoexpressionNABA_MATRISOME

WNT5B CELA3A FBN1 EGF FN1 AEBP1 LAMA1 CRELD2 LAMC3 IL36G MEGF11

6.53e-0610085511MM17056
CoexpressionHU_FETAL_RETINA_FIBROBLAST

FBN1 FN1 AEBP1 LAMA1 LAMC3 NOTCH2 FOXC1

1.55e-05385557M39264
CoexpressionNABA_CORE_MATRISOME

FBN1 FN1 AEBP1 LAMA1 CRELD2 LAMC3

2.15e-05270556MM17057
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FBN1 FN1 AEBP1 ZNF423 AOX1 PKDCC

1.73e-072005562022df85df94ab8cbb4e80e3fe9894c01051c5e0
ToppCellBronchus_Control_(B.)-Stromal-TX|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

FBN1 FN1 AEBP1 ZNF423 AOX1 PKDCC

1.73e-0720055669b41f5fb370aa8840a9ad7919d03ef1e57d1b5b
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AEBP1 LAMA1 LAMC3 NOTCH2 FOXC1

2.05e-061685559930bd63b60c03f0152838a79eef77da1c2dd8e5
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AEBP1 LAMA1 LAMC3 NOTCH2 FOXC1

2.23e-061715552e43fb129ee9bdc3b31febc43c10f959bf0f4a7d
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AEBP1 LAMA1 LAMC3 NOTCH2 FOXC1

2.23e-06171555e219a1aa59a96e4bc3e2eacf985679174a51de41
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 WWOX EGF LAMA1 HIBADH

2.30e-061725551565f38266891c3acf49778838de134c5dee5460
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 FN1 AEBP1 PKDCC LAMC3

2.95e-06181555c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 FN1 AEBP1 PKDCC LAMC3

2.95e-06181555c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellfacs-Skin-nan-24m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FN1 AEBP1 PKDCC LAMC3

3.28e-061855558433a337625ff8398520e223ef92bf9bb0beb14c
ToppCellfacs-Skin-nan-24m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FN1 AEBP1 PKDCC LAMC3

3.28e-06185555049d793d043d5d434f143025de49dd210d18756c
ToppCellfacs-Skin-nan-24m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FN1 AEBP1 PKDCC LAMC3

3.28e-0618555563200c42565eea596f9b00728e70e544b8d50a7f
ToppCelldroplet-Heart-HEART-1m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MSH6 FN1 SCN1A MEGF11 FOXC1

4.03e-06193555d0a5f212f8e8a13dbbe3e41df92548ef82eef70b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WNT5B FBN1 FN1 ZNF423 ADGRL4

4.03e-061935550b328f725f6feba263783eaca60c142e80df90f3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 FN1 AEBP1 PKDCC LAMC3

4.13e-0619455502b8102be9414d6964cd71019613edff6d88b893
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 FN1 AEBP1 PKDCC LAMC3

4.13e-0619455529f83cdd63314fff41258937d70b881a5503bfcc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 FN1 AEBP1 PKDCC LAMC3

4.13e-06194555d3db241ea316bbcde6d16618193b474591ad5ce4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WNT5B FBN1 FN1 ZNF423 ADGRL4

4.13e-06194555b0c15e7e4bcf30856fb628dedd7ba82df33489f5
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FBN1 FN1 FOXC1 ADGRL4 STAB1

4.24e-06195555752a100297c26732e12bbbf3ab27a2bd4f5ea06d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WNT5B FBN1 FN1 ZNF423 ADGRL4

4.24e-0619555577e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuroepithelial|GW26 / Sample Type, Dataset, Time_group, and Cell type.

FBN1 FN1 AEBP1 LAMC3 FOXC1

4.79e-062005558b80811a0ec28d1d763c10b095d1969bccbe82d4
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuroepithelial-Proteoglycan-expressing_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

FBN1 FN1 AEBP1 LAMC3 FOXC1

4.79e-0620055552ec80f3922ae6ee3565d5993c2fc56bb3a3199a
ToppCellTracheal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FBN1 FN1 AEBP1 AOX1 ZFAND5

4.79e-06200555c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Hs3st6|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRIM25 AEBP1 LAMA1 FOXC1

9.39e-061075544a18261492371d19b8dbd403e197fdf64ef69392
ToppCellfrontal_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Spp1_Hs3st6|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRIM25 AEBP1 NOTCH2 FOXC1

1.63e-0512355464a2d7e40d9c948a9ccaf61c465fb2207e0b7ab8
ToppCell10x5'-Lung-Myeloid_Mac-Intestinal_macrophages|Lung / Manually curated celltypes from each tissue

FCGBP RPS6KL1 MEGF11 STAB1

2.78e-051415547671d300b1722711fd2d8034b96a3aa7e3ccb560
ToppCellSerous|World / shred by cell class for turbinate

FCGBP EGF PKDCC FOXC1

3.55e-051505546a326662d58b0f17d6efa8cc28571f4cbbf57c2d
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 EGF LAMA1 OPLAH

3.83e-051535540307f10e772021ae68a42690634df458672a6df9
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

AEBP1 AOX1 LAMA1 LAMC3

3.93e-0515455465dbb60f636562eeba3dafadae9c0c7db2b27476
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Hippocampus / BrainAtlas - Mouse McCarroll V32

AOX1 LAMA1 LAMC3 FOXC1

4.45e-0515955492049a8d8fc9997d8d0d76500c72596a9b2394e0
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRIM25 FN1 FOXC1 ADGRL4

4.67e-05161554a60ef3f390f56bb05b687b17986fe6382f69f260
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell-Endo|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRIM25 FN1 FOXC1 ADGRL4

4.79e-051625540bdb1e5ba33e162bec1acb28256c1405a7658ee5
ToppCellprimary_visual_cortex-Non-neuronal-endothelial_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRIM25 FN1 FOXC1 ADGRL4

4.79e-051625545799a602ef8d83925907e8e34532428be7330228
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRIM25 FN1 FOXC1 ADGRL4

5.02e-051645546a41a159134e605b80d5e731f9ed5bc803bb531b
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRIM25 FN1 FOXC1 ADGRL4

5.02e-05164554ec68954fc09b6850273b5e59caa6b09d02151097
ToppCellfrontal_cortex-Non-neuronal-endothelial_cell-Endo-Endo_Ctla2a|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

TRIM25 FN1 FOXC1 ADGRL4

5.26e-0516655427af6c906cff1d40d134f0386db7708869691121
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 AEBP1 FEZF1 SLC25A34

5.39e-05167554805129f887078340b260aa136b0ba19f2bd6ea03
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 AEBP1 FEZF1 SLC25A34

5.39e-0516755431cf8bf2eb523f6e7e319620648ff37fc09e2601
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FN1 AEBP1 FEZF1 SLC25A34

5.39e-051675543acb18428d1d33ad430c2fd031b1a91baee3c01d
ToppCellHippocampus-Endothelial-ENDOTHELIAL_TIP|Hippocampus / BrainAtlas - Mouse McCarroll V32

AEBP1 LAMA1 LAMC3 FOXC1

5.51e-0516855426aa96b2b547d11941cb803995ea3d302ee0518c
ToppCellPND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AEBP1 SCN1A RPS6KL1 STAB1

5.64e-05169554f077e39e41fffe7672541f5b72b80faaf56c597c
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

FBN1 AEBP1 AOX1 LAMC3

5.64e-0516955447fd4adfe54777e69a0fabf8bd34f26223f63275
ToppCell367C-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

FBN1 AEBP1 AOX1 LAMC3

5.64e-05169554e09259d62cd3e42f0919f231ed1164db59b0b6c3
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBN1 AEBP1 AOX1 PKDCC

6.04e-05172554e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellCD8+_Memory_T_cell-FLU-3|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

MSH6 PTPRK ITGAX OPLAH

6.04e-0517255445ac433dbb3796f69e886c04457b2971403050ee
ToppCellFLU-Healthy-3|FLU / Virus stimulation, Condition and Cluster

MSH6 PTPRK ITGAX OPLAH

6.18e-0517355432b8e5b400885dbeba57a7cb2c18d882664dc285
ToppCellFLU-Healthy-3|Healthy / Virus stimulation, Condition and Cluster

MSH6 PTPRK ITGAX OPLAH

6.18e-0517355426e89ac86922f1cd0100cf4d1cce37e74dd31c88
ToppCelldroplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP EFCAB6 AEBP1 LAMA1

6.32e-05174554a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AEBP1 LAMA1 LAMC3 FOXC1

6.32e-051745542891ab2fd05eb4bbd239d1a2865f21ef7f2df39e
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AEBP1 LAMA1 LAMC3 FOXC1

6.32e-05174554eade55f86ef1f7a5355ad65cec3aa6bfc5d3c62d
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

WNT5B FCGBP PKDCC STAB1

6.46e-05175554bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCellNS-moderate-d_07-13-Lymphoid-NK|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FBN1 FN1 AEBP1 LAMC3

6.46e-05175554f6cd24d22f62469319f9d244e3e5de527d3d4d94
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 FN1 AEBP1 LAMC3

6.60e-051765549bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

FBN1 FN1 AEBP1 AOX1

6.60e-051765542e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FBN1 FN1 AEBP1 LAMC3

6.60e-051765543f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

FBN1 FN1 AEBP1 AOX1

6.60e-05176554f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCellprimary_visual_cortex-Non-neuronal-leptomeningeal_cell-VLMC-VLMC_Osr1_Mc5r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

AEBP1 LAMA1 LAMC3 FOXC1

6.75e-05177554599cf7f5b774e197a1b43c98e4b9a8c1a618f38a
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

FBN1 FN1 LY6G6D AEBP1

6.90e-05178554edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 EGF LAMA1 HIBADH

6.90e-05178554dfed0fbf7a73b8a9e00178ec58dc4592b271c344
ToppCell356C-Fibroblasts-Fibroblast-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

WNT5B FBN1 ZNF423 AOX1

6.90e-05178554a493a277d175e5e153410a745b26ebe2e0839ea0
ToppCell356C-Fibroblasts-Fibroblast-E|356C / Donor, Lineage, Cell class and subclass (all cells)

WNT5B FBN1 ZNF423 AOX1

6.90e-05178554371218babddfd3d8a7bb82a46ce65327ee3fcf12
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 EGF LAMA1 HIBADH

7.05e-05179554d0fa700648db8ce76a8aa689879a25048299fa40
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 EGF LAMA1 HIBADH

7.05e-051795542e49b215b71438400aebb483f2c2c08d5e956961
ToppCellmild_COVID-19-NK_CD56bright|mild_COVID-19 / disease group, cell group and cell class (v2)

KLHL23 ITGAX IL36G FOXC1

7.21e-05180554d8b418edd807a51c0b5f4018b8b478dcc65892a7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 WWOX EGF LAMA1

7.21e-051805549e09b3dfe344b5d50520711513d389865d73a861
ToppCellE15.5-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FBN1 FN1 KLHL23 FOXC1

7.21e-0518055438035cf2c6fbc443ea10ca7e942572715ed572da
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FN1 AEBP1 ZNF423 NPC1L1

7.21e-0518055412537d8a569faa69f474284d2c201475722b8ca1
ToppCellRA-01._Fibroblast_I|World / Chamber and Cluster_Paper

FBN1 FN1 AOX1 PKDCC

7.36e-051815542b6ddeb53a79a658e2ba78527ff48c155b20daa6
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBN1 FN1 AEBP1 AOX1

7.36e-05181554b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AEBP1 ZNF423 LAMA1 NOTCH2

7.36e-051815540c3f469bed108994ed696230e3c30343f7a301d3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FN1 PTPRK LAMC3 FOXC1

7.52e-05182554fc4a5bf784705efe7965ce43ac23c2a8e602e90a
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP SLC12A1 EGF LY6G6D

7.52e-05182554b8be66a867ea1bbae0820b26dbd55b68611f5ad5
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 EGF LAMA1 HIBADH

7.52e-05182554041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP SLC12A1 EGF LY6G6D

7.52e-05182554cb488f9a9b200e2557335ccf22535cd247512cdc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 EGF LAMA1 HIBADH

7.68e-0518355431ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellmild_COVID-19-NK_CD56bright|World / disease group, cell group and cell class (v2)

KLHL23 ITGAX IL36G FOXC1

7.68e-051835549a4899afac0f91203209392c5f67b3d0aa356b86
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

AEBP1 AOX1 LAMA1 NOTCH2

7.85e-05184554235890e8b424f4386b6ea52d173d20a00898df73
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 HOXC10 FN1 AEBP1

7.85e-05184554fea4fe648e9749177d0783443dc26a7df5807883
ToppCell(2)_5-FU-(4)_COL2.3+_osteoblasts|World / Stress and Cell class

WNT5B FN1 AEBP1 U2AF1L4

7.85e-05184554684d05340a3dfb8aa08b881516a37f9627a10448
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 HOXC10 FN1 AEBP1

7.85e-0518455496a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 HOXC10 FN1 AEBP1

7.85e-05184554780eb72da43527f0c72effac3423ec7384f05f20
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 WWOX EGF LAMA1

8.01e-0518555403f64a7132b13a01ba47187e0e15c13ac88f7cb2
ToppCell3'-Broncho-tracheal_SMG-Epithelial-Epithelial_transtional-secretory-SMG_acinar_cell-SMG_duct-SMG_duct_L.0.6.2.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGBP EGF PKDCC FOXC1

8.01e-05185554c4ca213a59ffab183a7719c2b4bc3f658a95002d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 EGF LAMA1 HIBADH

8.01e-05185554898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FBN1 FN1 AEBP1 AOX1

8.18e-051865545473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 WWOX EGF LAMA1

8.18e-051865541850583d23903d08226aeb0edb3e07b0994330e4
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 WWOX EGF LAMA1

8.18e-051865544dafc215c42e7949f932a3627359c107943b5d6b
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 EGF LAMA1 HIBADH

8.35e-05187554b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCelldroplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT5B RPS6KL1 FOXC1 STAB1

8.35e-051875549c9ae8725905ba0cfe407878006ed06c2480fb72
ToppCelldroplet-Lung-LUNG-1m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WNT5B RPS6KL1 FOXC1 STAB1

8.35e-051875549e9460e57cdc9cd0a0de2866b140e06d0bc19a8f
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

WNT5B TRIM25 AEBP1 ADAT2

8.52e-051885548231e635706a296db6b6da1029a33bbc1b52478e
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WNT5B RPS6KL1 FOXC1 STAB1

8.52e-05188554dc52dd2957be3f40001f0a56f3d9ac9d66ea466e
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WNT5B RPS6KL1 FOXC1 STAB1

8.52e-051885542ef08313087e91985bcffc46c3798470cdeec49c
ToppCelldroplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WNT5B RPS6KL1 FOXC1 STAB1

8.52e-051885541f1604b6dc0a8ad0be3d9aac0bef448459c22465
ToppCellfacs-Thymus-Epithelium-3m-Mesenchymal|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FN1 AEBP1 OPLAH

8.70e-051895541db5dd1ef2a65251af2d5696622d1dd9c4ae2b55
ToppCellfacs-Thymus-Epithelium-3m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FN1 AEBP1 OPLAH

8.70e-05189554bfb1c183a8a2752a2368b74150e66181c6a9da48
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

WNT5B FBN1 FN1 ADGRL4

8.70e-0518955412b6f1c3bf526b90e112374bf937701f645c5780
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 WWOX EGF LAMA1

8.70e-05189554830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellfacs-Diaphragm-Limb_Muscle-18m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FN1 AEBP1 CRELD2

8.70e-05189554dde037322c8caec0c04c5be1c1b59a167824ad9f
ToppCellfacs-Thymus-Epithelium-3m-Mesenchymal-fibroblast|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBN1 FN1 AEBP1 OPLAH

8.70e-0518955414833feea8f80744a06ece73f813eaeff8c4dd61
ToppCellAdult|World / Lineage, Cell type, age group and donor

TRIM25 EGF SCN1A ITGAX

8.70e-051895545cd285bfad973125d46d704fec18b21266a63379
Diseaseconnective tissue disease (implicated_via_orthology)

FBN1 FBN3

8.78e-063512DOID:65 (implicated_via_orthology)
DiseaseHodgkins lymphoma

FCGBP PTPRK MEGF11 STAB1

1.25e-0582514EFO_0000183
Diseasecortical thickness

FBN1 WWOX ZNF423 LAMA1 PKDCC LAMC3 ATP13A2 MTCH2 STAB1

1.09e-041113519EFO_0004840
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN8A

1.31e-0410512DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN8A

1.31e-0410512DOID:0080422 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

SLC12A1 WWOX SCN1A SCN8A

1.83e-04163514DOID:1826 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN8A

1.91e-0412512DOID:0060170 (implicated_via_orthology)
Diseasepeak expiratory flow

WWOX PTPRK CRELD2 ATP13A2 MTCH2 FBN3

2.12e-04498516EFO_0009718
DiseaseGlioblastoma

EGF FN1 NOTCH2

3.51e-0479513C0017636
DiseaseGiant Cell Glioblastoma

EGF FN1 NOTCH2

4.20e-0484513C0334588
Diseasecortical surface area measurement

FBN1 WWOX ZNF423 PKDCC LAMC3 ATP13A2 MTCH2 RPS6KL1 FBN3

4.46e-041345519EFO_0010736
Diseaseanxiety

EFCAB6 MTCH2 RPS6KL1 STAB1

6.01e-04223514EFO_0005230
DiseaseProstatic Neoplasms

U2AF1 EGF PTPRK AOX1 ZFAND5 FOXC1

6.55e-04616516C0033578
DiseaseMalignant neoplasm of prostate

U2AF1 EGF PTPRK AOX1 ZFAND5 FOXC1

6.55e-04616516C0376358
DiseaseGlioblastoma Multiforme

EGF FN1 NOTCH2

9.46e-04111513C1621958
Diseasemyeloid white cell count

CELA3A EGF FN1 ZNF423 POLI NOTCH2 ADGRL4

1.09e-03937517EFO_0007988
Diseasevital capacity

WWOX FN1 PKDCC ATP13A2 HIBADH MTCH2 FBN3 ADGRL4

1.19e-031236518EFO_0004312
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Positive

WWOX EGF STAB1

1.52e-03131513C4704862
DiseasePolyarthritis, Juvenile, Rheumatoid Factor Negative

WWOX EGF STAB1

1.52e-03131513C4552091
DiseaseJuvenile arthritis

WWOX EGF STAB1

1.52e-03131513C3495559
DiseaseJuvenile psoriatic arthritis

WWOX EGF STAB1

1.52e-03131513C3714758
DiseaseSpinocerebellar Ataxia Type 2

WWOX FOXC1

1.59e-0334512C0752121
DiseaseSpinocerebellar Ataxia Type 1

WWOX FOXC1

1.59e-0334512C0752120
DiseaseSpinocerebellar Ataxia Type 5

WWOX FOXC1

1.59e-0334512C0752123
DiseaseSpinocerebellar Ataxia Type 7

WWOX FOXC1

1.59e-0334512C0752125
DiseaseSpinocerebellar Ataxia Type 6 (disorder)

WWOX FOXC1

1.59e-0334512C0752124
DiseaseAtaxia, Spinocerebellar

WWOX FOXC1

1.59e-0334512C0087012
DiseaseJuvenile-Onset Still Disease

WWOX EGF STAB1

1.66e-03135513C0087031
DiseaseSpinocerebellar Ataxia Type 4

WWOX FOXC1

1.68e-0335512C0752122

Protein segments in the cluster

PeptideGeneStartEntry
RNGIEACYCNMGFSG

ADGRL4

36

Q9HBW9
LVVYGCQNERFGGCG

ADAT2

121

Q7Z6V5
ECREACGGHGYLAMN

ACOX3

421

O15254
RGGCQAQDYTGGMGI

AEBP1

831

Q8IUX7
CGQGYSLMPDGRACA

FBN3

1181

Q75N90
NLPGMFRCICNGGYE

FBN3

1421

Q75N90
DLMGSLAYCLACGGG

DHCR7

411

Q9UBM7
GGGCGACTVMISRYN

AOX1

46

Q06278
SNLMAVNNCGLAGGC

MTCH2

241

Q9Y6C9
CGRNMYLTGLCFLLG

ITGAX

116

P20702
LNGGQCMDRIGGYSC

NOTCH2

1236

Q04721
GTFGYGCQQLCECMN

MEGF11

786

A6BM72
CNGGLGNMGELPAYT

NKX2-4

111

Q9H2Z4
LCLANYSRGGDGPMC

MSH6

1061

P52701
GTMCGVYGSALCNAQ

NPC1L1

186

Q9UHC9
LQKLQYCVGMCGDGA

ATP13A2

866

Q9NQ11
QTIGNSCKACGYRGM

EIF5

116

P55010
GDADGGGRAVYQSMC

IL36G

6

Q9NZH8
CGAVIMNGCIYVTGG

KLHL23

501

Q8NBE8
LCGMVYATGGRNRAG

KLHL26

411

Q53HC5
YINGIKRGGGNEMNC

EFCAB6

141

Q5THR3
NTEGGYTCMCAGRLS

EGF

931

P01133
GMQCAAGQRCQVVGG

FCGBP

446

Q9Y6R7
MCGLCGNYNGDPKDD

FCGBP

1386

Q9Y6R7
SYHGAVCGLCGNMDR

FCGBP

1806

Q9Y6R7
LMCGLCGNYNGDPKD

FCGBP

2586

Q9Y6R7
QLMCGLCGNYNGDPK

FCGBP

3786

Q9Y6R7
GGYMLECVCLGNGKG

FN1

161

P02751
GICMNGRCVNTDGSY

FBN1

621

P35555
LNAPGGYRCECDMGF

FBN1

1421

P35555
GAGGAGTYHCNLQAM

FOXC1

386

Q12948
TMVCAGGYIRSGCNG

CELA3A

201

P09093
GSDFNCGVMRGCGLA

HOXC10

36

Q9NYD6
QGDGSCRCHMGYQGP

CRELD2

161

Q6UXH1
AMYNQLGLTGCAGVA

POLI

211

Q9UNA4
CLNGGGRSGMFCAIG

PTPRK

1376

Q15262
LLSVNMGGEQCGGCR

PLEKHM2

816

Q8IWE5
MGGEQCGGCRRANTT

PLEKHM2

821

Q8IWE5
AALGNRMRCYNCGGS

LY6G6D

16

O95868
GCAALRNVSGAQYMG

PKDCC

131

Q504Y2
TAGRGQLYGGLTDCM

SLC25A34

241

Q6PIV7
LGAFGACAASQGCMN

OPLAH

1091

O14841
AMGALCYLNRGDGPC

FEZF1

156

A0PJY2
RGGGVCINCLQNTMG

LAMA1

356

P25391
SGMNCNGSAACGLGY

SLC12A1

451

Q13621
MGAGSGAYLRGCQRC

TMEM151A

366

Q8N4L1
CGNSSDAGQCPEGYM

SCN1A

336

P35498
QELLGCMGSNVVYCG

HIBADH

186

P31937
CMGSNVVYCGAVGTG

HIBADH

191

P31937
TGCGFYGNPRTNGMC

ZFAND5

16

O76080
EGNMGLVNYVGRCGA

SLC27A5

436

Q9Y2P5
NNFCGVGICYGSMNR

TRIM25

521

Q14258
TGCGFYGNPRTNGMC

ZFAND6

16

Q6FIF0
MDGCELMCCGRGYNQ

WNT5B

311

Q9H1J7
PELEGLGGMYFNNCC

WWOX

366

Q9NZC7
GQCPEGYQCMKAGRN

SCN8A

331

Q9UQD0
APGQRTCTCQDGYMG

STAB1

1476

Q9NY15
LGGCGRGMDQSCLSA

RPS6KL1

356

Q9Y6S9
RQYEMGECTRGGFCN

U2AF1

156

Q01081
RQYEMGECTRGGFCN

U2AF1L4

156

Q8WU68
CDGCKNHIGMGVRYN

YJU2B

56

P13994
LCAGCMARSANGQVG

ZNF423

1091

Q2M1K9
GMGACYDGAGRPQRC

LAMC3

21

Q9Y6N6