Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentnuclear pore nuclear basket

RANBP2 CETN2 NUP153

8.47e-05181013GO:0044615
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

RANBP2 USP24 NAP1L1 NARS1 ABCF2 PARVB IDH2 RFC1 NSUN2 USP16 HNRNPAB MRPS25 AHNAK IMP4 CCAR1 DDX41 RPL3 CPSF3 MRPL1 NUP153

1.67e-0913181032030463901
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

RANBP2 CETN2 NAP1L1 RFC1 NSUN2 HNRNPAB RIF1 AHNAK IMP4 SUGP1 CCAR1 KIF18B DDX41 RPL3 CPSF3 NUP153 VCP

5.26e-099891031736424410
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

RANBP2 NAP1L1 NARS1 ABCF2 IDH2 RFC1 NSUN2 HNRNPAB EHD4 ITPR2 UBE4A TOMM70 MRPS25 AHNAK TRAPPC10 DDX41 MRPL1 HEATR3 VCP AHNAK2

7.47e-0914401032030833792
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RANBP2 NAP1L1 NARS1 ABCF2 RFC1 NSUN2 USP16 HNRNPAB EHD4 RIF1 AHNAK CCAR1 AKAP10 KIF18B DDX41 RPL3 CPSF3 VCP AHNAK2

1.57e-0813531031929467282
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

RANBP2 CETN2 NAP1L1 RFC1 HNRNPAB RIF1 ACTR6 AHNAK KIF18B DDX41 NUP153

2.70e-083941031127248496
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RANBP2 USP24 NAP1L1 NARS1 RFC1 NSUN2 RIF1 AHNAK CCAR1 RPL3 CPSF3 NUP153 VCP

7.30e-086531031322586326
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RANBP2 NAP1L1 RFC1 NSUN2 USP16 HNRNPAB RIF1 ALMS1 AHNAK SUGP1 RPL3 CPSF3 NUP153 VCP AHNAK2

1.10e-079341031533916271
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RANBP2 TRIO NAP1L1 ABCF2 IDH2 RFC1 NSUN2 HNRNPAB EHD4 MAPRE1 UBE4A TOMM70 RIF1 CCAR1 DDX41 RPL3 CPSF3 NUP153

1.92e-0714251031830948266
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

RANBP2 CETN2 NAP1L1 NARS1 RFC1 NSUN2 MAPRE1 RIF1 AHNAK CCAR1 MYO15A DDX41 CPSF3 NUP153 VCP

3.15e-0710141031532416067
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

PEX6 IDH2 ZDHHC17 HNRNPAB EHD4 ITPR2 UBE4A TOMM70 ALMS1 MRPS25 IMP4 TTC13 RERE DDX41 RPL3 MRPL1 VCP AHNAK2

3.90e-0714961031832877691
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

RANBP2 RFC1 HNRNPAB HDGFL3 RIF1 AHNAK SUGP1 ANKRD11 CCAR1 KIF18B DDX41 L3MBTL3 MRPL1 NUP153

8.89e-079541031436373674
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

RANBP2 CETN2 ABCF2 RFC1 HNRNPAB RIF1 ACTR6 AHNAK ANKRD11 CCAR1 KIF18B DDX41 L3MBTL3 RPL3 CPSF3 NUP153

1.31e-0612941031630804502
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RANBP2 CETN2 NAP1L1 ABCF2 RFC1 HNRNPAB RIF1 IMP4 CCAR1 RPL3 CPSF3 NUP153 VCP

1.38e-068471031335850772
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

RANBP2 NAP1L1 L1TD1 PARD3B RFC1 USP16 ALMS1 AHNAK CCAR1 L3MBTL3

1.39e-064691031027634302
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

RANBP2 CETN2 NAP1L1 NARS1 IDH2 RFC1 NSUN2 HNRNPAB MAPRE1 MRPS25 AHNAK DDX41 RPL3 NUP153 VCP

1.50e-0611491031535446349
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RANBP2 GRK6 NAP1L1 ABCF2 NSUN2 HNRNPAB EHD4 ITPR2 RIF1 AHNAK DDX41 RPL3 NUP153 VCP

2.03e-0610241031424711643
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

RANBP2 USP24 NAP1L1 HNRNPAB RIF1 CCAR1 DDX41 RPL3 CPSF3 NUP153 VCP

3.15e-066381031133239621
Pubmed

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

RANBP2 NAP1L1 ABCF2 RFC1 NSUN2 MRPS25 RERE DDX41 RPL3 SMYD3 NUP153

4.05e-066551031135819319
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CYLD GAD2 TRIO NAP1L1 RAP1GAP2 NARS1 PARVB SHROOM2 NSUN2 USP16 UBE4A RCBTB1 CCAR1 SMYD3 VCP

5.84e-0612851031535914814
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

RANBP2 NAP1L1 NARS1 NSUN2 EHD4 RIF1 AHNAK AHNAK2

6.86e-06332103832786267
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

MICAL1 RANBP2 NAP1L1 NARS1 ABCF2 HNRNPAB ITPR2 SUGP1 CCAR1 CPSF3 VCP

7.67e-067011031130196744
Pubmed

Kif18B interacts with EB1 and controls astral microtubule length during mitosis.

MAPRE1 KIF18B

8.69e-062103221737685
Pubmed

Serum response factor controls CYLD expression via MAPK signaling pathway.

CYLD SRF

8.69e-062103221573132
Pubmed

Isocitrate dehydrogenase 2 inhibits gastric cancer cell invasion via matrix metalloproteinase 7.

IDH2 MMP7

8.69e-062103226553362
Pubmed

The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

AHNAK AHNAK2

8.69e-062103215007166
Pubmed

AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness.

AHNAK AHNAK2

8.69e-062103220833135
Pubmed

Knockdown screens to knockout HIV-1.

RANBP2 NUP153

8.69e-062103218984154
Pubmed

Frequencies of Six (Five Novel) STR Markers Linked to TUSC3 (MRT7) or NSUN2 (MRT5) Genes Used for Homozygosity Mapping of Recessive Intellectual Disability.

TUSC3 NSUN2

8.69e-062103226427135
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

RANBP2 USP24 PARVB HNRNPAB EHD4 RIF1 AHNAK DDX41 CPSF3 NUP153

9.33e-065821031020467437
Pubmed

SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.

SCRT2 RANBP2 RFC1 RIF1 CCAR1 DDX41 NUP153

1.00e-05250103733536335
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

RANBP2 NAP1L1 ABCF2 AHNAK SUGP1 RPL3 AHNAK2

1.17e-05256103733397691
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

RANBP2 USP24 NAP1L1 NARS1 ABCF2 RFC1 NSUN2 HNRNPAB RIF1 MRPS25 AHNAK DDX41 RPL3 VCP AHNAK2

1.82e-0514151031528515276
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

RANBP2 USP24 RFC1 NSUN2 USP16 RIF1 CCAR1 TRAPPC10 RERE DDX41 NUP153

1.92e-057741031115302935
Pubmed

The tumour suppressor PTEN mediates a negative regulation of the E3 ubiquitin-protein ligase Nedd4.

NAP1L1 NARS1 AHNAK RPL3 VCP

1.98e-05110103518307411
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

NAP1L1 NARS1 ABCF2 RFC1 NSUN2 USP16 HNRNPAB ITPR2 MRPS25 AHNAK IMP4 DDX41 RPL3 NUP153

2.07e-0512571031436526897
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

RANBP2 NAP1L1 NARS1 RFC1 NSUN2 KHDC4 HNRNPAB SUGP1 CCAR1 DDX41 L3MBTL3 HEATR3 NUP153

2.34e-0511031031334189442
Pubmed

The functional interactome landscape of the human histone deacetylase family.

NARS1 IDH2 RIF1 ANKRD11 RERE DDX41 NUP153

2.55e-05289103723752268
Pubmed

Heterogeneous susceptibility of circulating SIV isolate capsids to HIV-interacting factors.

RANBP2 NUP153

2.60e-053103223883001
Pubmed

Self-regulated alternative splicing at the AHNAK locus.

AHNAK AHNAK2

2.60e-053103221940993
Pubmed

DNA polymerase POLD1 promotes proliferation and metastasis of bladder cancer by stabilizing MYC.

RANBP2 ABCF2 AHNAK NUP153 VCP

2.77e-05118103537105989
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

TRIO ABCF2 NSUN2 AHNAK SUGP1 RPL3 AHNAK2

3.10e-05298103730737378
Pubmed

PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.

NAP1L1 RFC1 HNRNPAB MRPS25 IMP4 TRAPPC10 DDX41 RPL3 MRPL1 VCP

3.44e-056781031030209976
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

NAP1L1 NARS1 ABCF2 NSUN2 USP16 TOMM70 MRPS25 AHNAK RPL3

3.73e-05547103937267103
Pubmed

mTORC2 interactome and localization determine aggressiveness of high-grade glioma cells through association with gelsolin.

ABCF2 IDH2 NSUN2 AHNAK RPL3 VCP AHNAK2

4.15e-05312103737120454
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

RANBP2 ABCF2 NSUN2 ITPR2 ACTR6 IMP4 RPL3 NUP153

5.13e-05440103834244565
Pubmed

Mammalian Scratch: a neural-specific Snail family transcriptional repressor.

SCRT2 SCRT1

5.19e-054103211274425
Pubmed

HIV-1 capsid-cyclophilin interactions determine nuclear import pathway, integration targeting and replication efficiency.

RANBP2 NUP153

5.19e-054103222174692
Pubmed

AHNAK, a novel component of the dysferlin protein complex, redistributes to the cytoplasm with dysferlin during skeletal muscle regeneration.

AHNAK AHNAK2

5.19e-054103217185750
Pubmed

Tpr is localized within the nuclear basket of the pore complex and has a role in nuclear protein export.

RANBP2 NUP153

5.19e-054103211839768
Pubmed

Molecular mechanisms of retroviral integration site selection.

RANBP2 NUP153

5.19e-054103225147212
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

NAP1L1 RFC1 NSUN2 HNRNPAB MRPS25 CCAR1 DDX41 RPL3 CPSF3 MRPL1

5.24e-057131031029802200
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

CYLD RANBP2 CETN2 ABCF2 USP16 MAPRE1 AHNAK CCAR1 KIF18B AHNAK2

5.95e-057241031036232890
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

SHROOM2 CDC42EP3 RIF1 ALMS1 DNAH11 PGBD2

7.05e-05233103637704626
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

ATE1 TOMM70 RCBTB1 MRPS25 IMP4 CCAR1 CEBPZOS CPSF3 HEATR3 NUP153

8.32e-057541031033060197
Pubmed

Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.

GAD2 TPH1

8.64e-055103223500099
Pubmed

A giant nucleopore protein that binds Ran/TC4.

RANBP2 NUP153

8.64e-05510327603572
Pubmed

A complex of Kif18b and MCAK promotes microtubule depolymerization and is negatively regulated by Aurora kinases.

MAPRE1 KIF18B

8.64e-055103221820309
Pubmed

RanGTP mediates nuclear pore complex assembly.

RANBP2 NUP153

8.64e-055103212894213
Pubmed

The N-terminal domain of the mammalian nucleoporin p62 interacts with other nucleoporins of the FXFG family during interphase.

RANBP2 NUP153

8.64e-055103216730000
Pubmed

A model for cofactor use during HIV-1 reverse transcription and nuclear entry.

RANBP2 NUP153

8.64e-055103224525292
Pubmed

Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains.

RANBP2 NUP153

8.64e-055103212138183
Pubmed

The expression of Scratch genes in the developing and adult brain.

SCRT2 SCRT1

8.64e-055103216773660
Pubmed

HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry.

RANBP2 NUP153

8.64e-055103226109731
Pubmed

SHLD2/FAM35A co-operates with REV7 to coordinate DNA double-strand break repair pathway choice.

CETN2 RFC1 NSUN2 ITPR2 KIF18B

8.70e-05150103530154076
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

USP24 NAP1L1 NARS1 ABCF2 ATE1 NSUN2 HNRNPAB EHD4 MAPRE1 AHNAK AKAP10 RPL3 VCP AHNAK2

1.00e-0414551031422863883
Pubmed

Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.

RANBP2 ABCF2 RFC1 EHD4 ITPR2 MRPS25 AHNAK RPL3 VCP

1.05e-04626103933644029
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

RANBP2 USP24 NAP1L1 ABCF2 ZDHHC17 NSUN2 TOMM70 TTC13 HEATR3 NUP153 VCP

1.12e-049421031131073040
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

RANBP2 TRIO NAP1L1 MYOZ2 ABCF2 TOMM70 ALMS1 VCP

1.19e-04497103823414517
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

TRIO TUSC3 USP24 RFC1 HNRNPAB PNPO MAPRE1 AHNAK CCAR1 TTC13 RPL3 CPSF3 VCP

1.21e-0412971031333545068
Pubmed

Huntingtin-interacting protein HIP14 is a palmitoyl transferase involved in palmitoylation and trafficking of multiple neuronal proteins.

GAD2 ZDHHC17

1.29e-046103215603740
Pubmed

Gradient of increasing affinity of importin beta for nucleoporins along the pathway of nuclear import.

RANBP2 NUP153

1.29e-046103211266456
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

CYLD RFC1 ALMS1 ACTR6 AHNAK CCAR1 KIF18B L3MBTL3 CPSF3

1.31e-04645103925281560
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

NAP1L1 NSUN2 HNRNPAB MAPRE1 SUGP1 CCAR1 DDX41 RPL3 MRPL1 VCP

1.45e-048071031022681889
Pubmed

Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.

NAP1L1 RFC1 NSUN2 HNRNPAB MAPRE1 AHNAK CCAR1 RPL3 NUP153 VCP

1.48e-048091031032129710
Pubmed

UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.

RANBP2 ABCF2 AHNAK SUGP1 RPL3 VCP

1.48e-04267103633417871
Pubmed

Insights into the ubiquitin-proteasome system of human embryonic stem cells.

L1TD1 NSUN2 EHD4 AHNAK ANKRD11 DDX41

1.55e-04269103629511261
Pubmed

Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.

RANBP2 RFC1 HNRNPAB AHNAK RPL3 NUP153

1.61e-04271103632433965
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

NSUN2 HNRNPAB CCAR1 DDX41 CPSF3 VCP

1.71e-04274103634244482
Pubmed

Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN.

CYLD VCP

1.81e-047103224461064
Pubmed

Centrin 2 localizes to the vertebrate nuclear pore and plays a role in mRNA and protein export.

CETN2 NUP153

1.81e-047103218172010
Pubmed

SMARCA3, a chromatin-remodeling factor, is required for p11-dependent antidepressant action.

AHNAK AHNAK2

1.81e-047103223415230
Pubmed

Enzymes of the SUMO modification pathway localize to filaments of the nuclear pore complex.

RANBP2 NUP153

1.81e-047103212192048
Pubmed

Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.

TRIO MAPRE1

1.81e-047103225065758
Pubmed

New insights in the role of nucleoporins: a bridge leading to concerted steps from HIV-1 nuclear entry until integration.

RANBP2 NUP153

1.81e-047103224051001
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

RANBP2 NAP1L1 NARS1 HNRNPAB EHD4 TOMM70 AHNAK IMP4 RPL3 VCP

2.08e-048441031025963833
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

CYLD RANBP2 TRIO KIAA0232 NAP1L1 PARD3B ATE1 MAPRE1 ALMS1 DDX41

2.26e-048531031028718761
Pubmed

Roles of HIV-1 capsid in viral replication and immune evasion.

RANBP2 NUP153

2.40e-048103225036886
Pubmed

CYLD deubiquitinates plakoglobin to promote Cx43 membrane targeting and gap junction assembly in the heart.

CYLD MAPRE1

2.40e-048103236577382
Pubmed

Genome-wide association study of inattention and hyperactivity-impulsivity measured as quantitative traits.

PARD3B MAPRE1

2.40e-048103223527680
Pubmed

CYLD coordinates with EB1 to regulate microtubule dynamics and cell migration.

CYLD MAPRE1

2.40e-048103224552808
Pubmed

Imaging within single NPCs reveals NXF1's role in mRNA export on the cytoplasmic side of the pore.

RANBP2 NUP153

2.40e-048103231375530
Pubmed

Targeting UBE4A Revives Viperin Protein in Epithelium to Enhance Host Antiviral Defense.

RANBP2 UBE4A

2.40e-048103231812350
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CYLD UAP1 TRIO KIAA0232 PARD3B ALMS1 AHNAK ANKRD11 DDX41 AHNAK2

2.43e-048611031036931259
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

RANBP2 USP24 NARS1 ABCF2 ATE1 AHNAK RPL3 NUP153 VCP

2.61e-04708103939231216
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

RANBP2 NARS1 IDH2 NSUN2 HNRNPAB MAPRE1 TOMM70 RPL3 VCP

2.70e-04711103933022573
Pubmed

USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.

ABCF2 IDH2 RFC1 NSUN2 EHD4 KIF18B CPSF3 VCP

2.84e-04565103833567341
Pubmed

Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.

CDC42EP3 CLVS1 DNAH11

2.86e-0443103321116278
Pubmed

Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.

NAP1L1 PARD3B NSUN2 MAPRE1 SUGP1 KIF18B RPL3 MRPL1 VCP

3.05e-04723103934133714
Pubmed

Cloning and characterization of human karyopherin beta3.

RANBP2 NUP153

3.08e-04910329114010
Pubmed

Human transcription factor protein interaction networks.

CYLD ETV7 RFC1 NSUN2 RIF1 ALMS1 ACTR6 MRPS25 SUGP1 CCAR1 RERE L3MBTL3 MRPL1

3.11e-0414291031335140242
InteractionH2BC3 interactions

CYLD RANBP2 CETN2 NAP1L1 RFC1 USP16 HNRNPAB RIF1 ACTR6 AHNAK KIF18B NUP153

1.00e-0640610212int:H2BC3
GeneFamilyZinc fingers C2H2-type|SNAG transcriptional repressors

SCRT2 SCRT1

6.15e-04106821259
GeneFamilyAAA ATPases

PEX6 RFC1 VCP

1.04e-0353683413
GeneFamilyUbiquitin specific peptidases

CYLD USP24 USP16

1.22e-0356683366
GeneFamilyPDZ domain containing

PARD3B SHROOM2 AHNAK AHNAK2

2.58e-031526841220
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

RANBP2 NUP153

2.79e-032168289
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_large-bowel / Manually curated celltypes from each tissue

CYP2J2 L1TD1 RAP1GAP2 B3GALT5 HDGFL3 HEATR3

2.45e-06166103613bef304ea3df8e8d2bc376a3287c78220a1b0c6
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLSCR4 GAD2 PARVB TTLL7 EHD4 MAPK12

5.33e-061901036cb8798839c27f307955fcc94a1ee40bca95b8e99
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLSCR4 GAD2 PARVB TTLL7 EHD4 MAPK12

5.33e-0619010365bf3d0beee69879c95265d07fba023626a7cc808
DrugMorantel tartrate [26155-31-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A

TRIO GRK6 TUSC3 ZDHHC17 HDGFL3 ALMS1 RCBTB1 SUGP1

3.33e-0619810387010_DN
Diseasewhole-brain volume

CLVS1 DNAH11

1.13e-0451002EFO_0005089
Diseaseurate measurement, bone density

PLSCR4 NXPH1 RAP1GAP2 CLVS1 ITPR2 MRPS25 ANKRD11 NUP153 DNAH11

2.59e-046191009EFO_0003923, EFO_0004531
Diseaseliver fat measurement

PARVB ADH1B SUGP1

4.22e-04431003EFO_0010821
Diseaserenal hypertension (biomarker_via_orthology)

CYP2J2 MMP7

5.03e-04101002DOID:1073 (biomarker_via_orthology)
Diseasetrimethylamine-N-oxide measurement

ITPR2 TTC13

1.01e-03141002EFO_0010541
Diseasealcohol use disorder (is_implicated_in)

ADH1B TPH1

1.32e-03161002DOID:1574 (is_implicated_in)
Diseaselymphocyte count

PLSCR4 GAD2 KIAA0232 RAP1GAP2 CLHC1 HDGFL3 ITPR2 ALMS1 AHNAK ANKRD11 RERE L3MBTL3 PGBD2

1.34e-03146410013EFO_0004587
Diseaseaspartate aminotransferase to alanine aminotransferase ratio

SCRT1 NARS1 PEX6 USP16 AHNAK

1.35e-032391005EFO_0010934

Protein segments in the cluster

PeptideGeneStartEntry
FSTIKKGFCKPREEM

ACTR6

241

Q9GZN1
KGFCKPREEMVLSGK

ACTR6

246

Q9GZN1
ALFPIGGKKAVMKFR

ERICH3

196

Q5RHP9
GFTPAMQRKKLKDFS

ABCF2

216

Q9UG63
GAVKEVMKFKQKPRF

CFAP54

1321

Q96N23
MARTLEPLAKKIFKG

CEBPZOS

1

A8MTT3
KKEPVTRKAGLLFGM

ANKRD11

86

Q6UB99
EKLAKVMGFLADKKP

CPSF3

461

Q9UKF6
QFKKREAFMPFSIGK

CYP2J2

431

P51589
PARLVKFLVGMKGKD

CCAR1

481

Q8IX12
PAMSFFRRKVKGKEQ

AKAP10

21

O43572
KEGIPKLVADFMAKK

ADH1B

326

P00325
EFKISKGLRMPFDEK

ALMS1

2661

Q8TCU4
KMLFTGYPEDRKLKK

ALMS1

3936

Q8TCU4
MVEAAKKNLGKAFLP

C4orf47

86

A7E2U8
KEMKAVKFPSQGTIF

DNAH11

2436

Q96DT5
GKERMVKGKQLKTFF

B3GALT5

81

Q9Y2C3
GKVKGSKFKMPFLSI

AHNAK

3396

Q09666
FFKELPKKVMKGVAD

ADCY10

441

Q96PN6
KELKVAMRALGFEPK

CETN2

51

P41208
MEYEVKKGKKGFVSP

CCM2L

1

Q9NUG4
KGKKFKLRDILSPDM

CDC42EP3

16

Q9UKI2
MDGPLLKEFIAKASK

RCBTB1

511

Q8NDN9
KAPKSGFEGMFTKKE

RANBP2

1711

P49792
RLKMFAKELKLVFPG

IMP4

96

Q96G21
LKDIKVKFSDAGQPM

NAP1L1

196

P55209
ILKAPFKEKAGEGSM

ITPR2

521

Q14571
FRVGMKLEAVDKKNP

L3MBTL3

371

Q96JM7
PSKKMKLFGFKEDPF

NSUN2

506

Q08J23
EDPERKIKKKGFGAM

PARD3B

861

Q8TEW8
FKMFPEVKEKGMAAL

GAD2

256

Q05329
VCFFKGADKELLPKM

DTD2

46

Q96FN9
EAKLKEMQKFFGLPI

MMP7

56

P09237
LPDMMIKGLFGKKEF

LIPM

231

Q5VYY2
LFMGFRDRTPKISKK

MYO15A

36

Q9UKN7
KSIRKAKFLPRGMEE

BMP15

241

O95972
FPLDLDVKMKAMIFG

PLSCR4

296

Q9NRQ2
ESGKFLPRLKKSGME

KIAA0232

1171

Q92628
GALKKMLTVEPAFQK

OR2T4

331

Q8NH00
MFFKVKKTVGEAPDG

PEX6

381

Q13608
FKTAVEAPLGMKLDK

EVC2

91

Q86UK5
KFVPEGFKVREMRGK

MICAL1

221

Q8TDZ2
MPSVFGKENKKRELI

EHD4

321

Q9H223
KPSARMLLLKGFGKD

PNPO

91

Q9NVS9
KSFKEMKFPAAILRG

DDX41

181

Q9UJV9
PREYKAGDLVFAKMK

HDGFL3

6

Q9Y3E1
PKKKGKDLTFVFDRV

KIF18B

61

Q86Y91
FAFELMLDGGLKKPK

PARVB

321

Q9HBI1
KEFQPVFKMKIRKEG

HEATR3

631

Q7Z4Q2
TFKMVFTPKDGSGVK

IDH2

191

P48735
LFRFLKTPGKMVQDK

ETV7

301

Q9Y603
LIKKGKDFSGRPQMA

CYP17A1

86

P05093
GFKRMGVDKIIPVDK

MAPRE1

81

Q15691
KMLKFLAKGEVPKGS

ATE1

96

O95260
PAKKMKTTEKGFGLV

KHDC4

551

Q7Z7F0
MPRFGKDFKLFKKIF

CYLD

756

Q9NQC7
PLFKKLNFKRLGAGM

GRK6

446

P43250
TVMEKRSFKVPLGKG

HMCES

101

Q96FZ2
KLFKEEFSPMKDGVK

DRP2

276

Q13474
PKEMRGKYKAALKAD

MRPS25

156

P82663
KGEAKKEKGMTFLPT

HHLA1

31

C9JL84
AMKKDPVKKIFVGGL

HNRNPAB

146

Q99729
EKPFMKLKENGRAIS

RAP1GAP2

621

Q684P5
MPRSFLVKKVKLDAF

SCRT1

1

Q9BWW7
MPRSFLVKKIKGDGF

SCRT2

1

Q9NQ03
FKTGLKALMTVGKEP

NARS1

26

O43776
RRPIVKTGKFKKMFG

NXPH1

106

P58417
KAFMGPLKKDRIAKE

RPL3

386

P39023
MDIRKFFGVIPSGKK

RFC1

1

P35251
KKDIKMGPFDVARKV

RFC1

841

P35251
MIKTDFLPKAKQREG

RIF1

1256

Q5UIP0
KKIDKISRIGFPMAF

GLRA1

421

P23415
KKFKMKLGTVPLREG

PYDC1

21

Q8WXC3
PMIGKLKFFIDEKYK

RNASEL

356

Q05823
VKGVCKPSEFDKFRM

SHROOM2

1476

Q13796
FMPLAGSKLAKKREE

RERE

1151

Q9P2R6
RVKKTMPFFLEGKPK

TDRD7

106

Q8NHU6
PKLLKRFFKTTMGSD

TEX45

361

Q8NA69
MEPLKVEKFATAKRG

SMYD3

1

Q9H7B4
PGKKTRGRVKIKMEF

SRF

136

P11831
PKFKMLSFGVSALGK

AHNAK2

2321

Q8IVF2
SRFKIPKFKMPSFGV

AHNAK2

2481

Q8IVF2
MNTFKAVGKIRGKPL

CLHC1

331

Q8NHS4
DMFKNFKADDPGIKR

CLVS1

106

Q8IUQ0
DPKELKKMKRGSFDY

PGBD2

386

Q6P3X8
KFMETFKALKEGREP

SUGP1

536

Q8IWZ8
FLMGPVKQLKKMFEA

SFT2D1

81

Q8WV19
MREFTKTIKRPFGVK

TPH1

386

P17752
TLDMALGKKKNVEPF

MRPL1

126

Q9BYD6
KIPKGKLVDFEAMTA

TTC13

791

Q8NBP0
FRMNGDKFRKFIKAP

TUSC3

66

Q13454
EKKKSMPSFVDRIFG

USP16

346

Q9Y5T5
KFKFPPAEGVSMRTK

TMPRSS11B

116

Q86T26
DKFLKFGMTPSKGVL

VCP

501

P55072
FKRSKKIMPAGLVAG

TMEM14A

71

Q9Y6G1
AMKGFEEVIKKFPRC

TOMM70

461

O94826
MSEGFKFSKPIGDFK

NUP153

946

P49790
DKPNGIKMEKFVFDI

UAP1

371

Q16222
EMKLKGKPDGSFLVR

SOCS7

411

O14512
KADKEFRQKVMLGTP

ZDHHC17

296

Q8IUH5
KGEKKGLFVEKMPAR

USP24

2101

Q9UPU5
PKMGALKVKDFSEFD

UBE4A

891

Q14139
VGKDLAEFYMRKKAP

TRAPPC10

481

P48553
FVLKDMKIRFPGKSD

TTLL7

686

Q6ZT98
IFSEPLDKKKGFSMP

TRIO

2196

O75962
LDKKKGFSMPGFLFK

TRIO

2201

O75962
APRFSGFRKEKAKMD

ZNF541

751

Q9H0D2
YMKGLPELEKKDFAS

MAPK12

261

P53778
PAKMAFDFRGKTKVF

L1TD1

826

Q5T7N2
PFGGFEKASRMVKFK

MYOZ2

191

Q9NPC6