Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	diacylglycerol binding	UNC13B UNC13C UNC13A	1.37e-06	16	28	3	GO:0019992
GeneOntologyMolecularFunction	phorbol ester receptor activity	UNC13B UNC13C	1.90e-06	2	28	2	GO:0001565
GeneOntologyMolecularFunction	non-kinase phorbol ester receptor activity	UNC13B UNC13C	1.90e-06	2	28	2	GO:0001566
GeneOntologyMolecularFunction	syntaxin-1 binding	UNC13B UNC13C UNC13A	4.90e-06	24	28	3	GO:0017075
GeneOntologyMolecularFunction	protein-cysteine S-palmitoyltransferase activity	ZDHHC2 ZDHHC7 ZDHHC16	6.28e-06	26	28	3	GO:0019706
GeneOntologyMolecularFunction	protein-cysteine S-acyltransferase activity	ZDHHC2 ZDHHC7 ZDHHC16	6.28e-06	26	28	3	GO:0019707
GeneOntologyMolecularFunction	S-acyltransferase activity	ZDHHC2 ZDHHC7 ZDHHC16	9.77e-06	30	28	3	GO:0016417
GeneOntologyMolecularFunction	palmitoyltransferase activity	ZDHHC2 ZDHHC7 ZDHHC16	1.86e-05	37	28	3	GO:0016409
GeneOntologyMolecularFunction	protein-cysteine S-myristoyltransferase activity	ZDHHC2 ZDHHC7	2.83e-05	6	28	2	GO:0019705
GeneOntologyMolecularFunction	protein-cysteine S-stearoyltransferase activity	ZDHHC2 ZDHHC7	3.96e-05	7	28	2	GO:0140439
GeneOntologyMolecularFunction	acyltransferase activity	ZDHHC2 ZDHHC7 RFFL RNF183 RNF2 ZZEF1 ZDHHC16	7.48e-05	775	28	7	GO:0016746
GeneOntologyMolecularFunction	myristoyltransferase activity	ZDHHC2 ZDHHC7	1.03e-04	11	28	2	GO:0019107
GeneOntologyMolecularFunction	syntaxin binding	UNC13B UNC13C UNC13A	2.42e-04	87	28	3	GO:0019905
GeneOntologyMolecularFunction	calmodulin binding	UNC13B UNC13C MYO9B UNC13A	2.83e-04	230	28	4	GO:0005516
GeneOntologyMolecularFunction	SNARE binding	UNC13B UNC13C UNC13A	8.94e-04	136	28	3	GO:0000149
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	EBF2 ZNF727 MECOM EBF1 EBF3	9.81e-04	560	28	5	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	EBF2 ZNF727 MECOM EBF1 EBF3	1.03e-03	566	28	5	GO:0001216
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	RFFL RNF183 RNF2 ZZEF1	2.18e-03	398	28	4	GO:0061659
GeneOntologyMolecularFunction	calcium ion binding	UNC13B HSPG2 UNC13C ZZEF1 UNC13A	3.51e-03	749	28	5	GO:0005509
GeneOntologyMolecularFunction	acyltransferase activity, transferring groups other than amino-acyl groups	ZDHHC2 ZDHHC7 ZDHHC16	4.40e-03	238	28	3	GO:0016747
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	RFFL RNF183 RNF2 ZZEF1	5.37e-03	512	28	4	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	RFFL RNF183 RNF2 ZZEF1	6.14e-03	532	28	4	GO:0016755
GeneOntologyBiologicalProcess	dense core granule priming	UNC13B UNC13C UNC13A	8.95e-09	4	28	3	GO:0061789
GeneOntologyBiologicalProcess	presynaptic dense core vesicle exocytosis	UNC13B UNC13C UNC13A	2.67e-07	10	28	3	GO:0099525
GeneOntologyBiologicalProcess	neuronal dense core vesicle exocytosis	UNC13B UNC13C UNC13A	4.89e-07	12	28	3	GO:0099011
GeneOntologyBiologicalProcess	dense core granule exocytosis	UNC13B UNC13C UNC13A	1.01e-06	15	28	3	GO:1990504
GeneOntologyBiologicalProcess	synaptic vesicle docking	UNC13B UNC13C UNC13A	1.50e-06	17	28	3	GO:0016081
GeneOntologyBiologicalProcess	dense core granule docking	UNC13B UNC13A	1.78e-06	2	28	2	GO:0061790
GeneOntologyBiologicalProcess	calcium ion-regulated exocytosis of neurotransmitter	UNC13B UNC13C UNC13A	5.05e-06	25	28	3	GO:0048791
GeneOntologyBiologicalProcess	dense core granule localization	UNC13B UNC13C UNC13A	7.17e-06	28	28	3	GO:0032253
GeneOntologyBiologicalProcess	synaptic vesicle priming	UNC13B UNC13C UNC13A	9.82e-06	31	28	3	GO:0016082
GeneOntologyBiologicalProcess	protein palmitoylation	ZDHHC2 ZDHHC7 ZDHHC16	1.19e-05	33	28	3	GO:0018345
GeneOntologyBiologicalProcess	secretory granule localization	UNC13B UNC13C UNC13A	1.30e-05	34	28	3	GO:0032252
GeneOntologyBiologicalProcess	synaptic vesicle exocytosis	UNC13B UNC13C UNC13A WNT7A	2.35e-05	125	28	4	GO:0016079
GeneOntologyBiologicalProcess	negative regulation of synaptic plasticity	UNC13B UNC13C	2.66e-05	6	28	2	GO:0031914
GeneOntologyBiologicalProcess	vesicle docking involved in exocytosis	UNC13B UNC13C UNC13A	2.86e-05	44	28	3	GO:0006904
GeneOntologyBiologicalProcess	synaptic transmission, glutamatergic	UNC13B UNC13C ZZEF1 UNC13A	2.91e-05	132	28	4	GO:0035249
GeneOntologyBiologicalProcess	regulation of synaptic plasticity	ZDHHC2 UNC13B UNC13C ZZEF1 UNC13A	4.20e-05	293	28	5	GO:0048167
GeneOntologyBiologicalProcess	vesicle docking	UNC13B UNC13C UNC13A	9.25e-05	65	28	3	GO:0048278
GeneOntologyBiologicalProcess	signal release from synapse	UNC13B UNC13C UNC13A WNT7A	1.33e-04	195	28	4	GO:0099643
GeneOntologyBiologicalProcess	neurotransmitter secretion	UNC13B UNC13C UNC13A WNT7A	1.33e-04	195	28	4	GO:0007269
GeneOntologyBiologicalProcess	regulation of synaptic vesicle priming	UNC13B UNC13A	1.60e-04	14	28	2	GO:0010807
GeneOntologyBiologicalProcess	calcium-ion regulated exocytosis	UNC13B UNC13C UNC13A	1.85e-04	82	28	3	GO:0017156
GeneOntologyBiologicalProcess	regulation of neuronal synaptic plasticity	ZDHHC2 UNC13B UNC13A	1.91e-04	83	28	3	GO:0048168
GeneOntologyBiologicalProcess	organelle localization by membrane tethering	UNC13B UNC13C UNC13A	2.05e-04	85	28	3	GO:0140056
GeneOntologyBiologicalProcess	modulation of chemical synaptic transmission	ZDHHC2 UNC13B UNC13C ZZEF1 UNC13A WNT7A	2.22e-04	663	28	6	GO:0050804
GeneOntologyBiologicalProcess	regulation of trans-synaptic signaling	ZDHHC2 UNC13B UNC13C ZZEF1 UNC13A WNT7A	2.24e-04	664	28	6	GO:0099177
GeneOntologyBiologicalProcess	membrane docking	UNC13B UNC13C UNC13A	2.51e-04	91	28	3	GO:0022406
GeneOntologyBiologicalProcess	protein lipidation	ZDHHC2 ZDHHC7 ZDHHC16	3.42e-04	101	28	3	GO:0006497
GeneOntologyBiologicalProcess	neurotransmitter transport	UNC13B UNC13C UNC13A WNT7A	3.92e-04	259	28	4	GO:0006836
GeneOntologyBiologicalProcess	lipoprotein biosynthetic process	ZDHHC2 ZDHHC7 ZDHHC16	3.94e-04	106	28	3	GO:0042158
GeneOntologyBiologicalProcess	regulation of short-term neuronal synaptic plasticity	UNC13B UNC13A	4.04e-04	22	28	2	GO:0048172
GeneOntologyBiologicalProcess	exocytic process	UNC13B UNC13C UNC13A	4.05e-04	107	28	3	GO:0140029
GeneOntologyBiologicalProcess	protein acylation	ZDHHC2 ZDHHC7 ZDHHC16	4.16e-04	108	28	3	GO:0043543
GeneOntologyBiologicalProcess	synaptic vesicle cycle	UNC13B UNC13C UNC13A WNT7A	4.22e-04	264	28	4	GO:0099504
GeneOntologyBiologicalProcess	peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine	ZDHHC2 ZDHHC7	4.81e-04	24	28	2	GO:0018231
GeneOntologyBiologicalProcess	peptidyl-L-cysteine S-palmitoylation	ZDHHC2 ZDHHC7	4.81e-04	24	28	2	GO:0018230
GeneOntologyBiologicalProcess	regulation of neurotransmitter secretion	UNC13B UNC13A WNT7A	5.39e-04	118	28	3	GO:0046928
GeneOntologyBiologicalProcess	regulated exocytosis	UNC13B UNC13C UNC13A WNT7A	6.08e-04	291	28	4	GO:0045055
GeneOntologyBiologicalProcess	vesicle-mediated transport in synapse	UNC13B UNC13C UNC13A WNT7A	8.78e-04	321	28	4	GO:0099003
GeneOntologyBiologicalProcess	regulation of neurotransmitter transport	UNC13B UNC13A WNT7A	9.04e-04	141	28	3	GO:0051588
GeneOntologyBiologicalProcess	innervation	UNC13B UNC13A	9.71e-04	34	28	2	GO:0060384
GeneOntologyBiologicalProcess	lipoprotein metabolic process	ZDHHC2 ZDHHC7 ZDHHC16	1.02e-03	147	28	3	GO:0042157
GeneOntologyBiologicalProcess	embryonic hindlimb morphogenesis	MECOM WNT7A	1.03e-03	35	28	2	GO:0035116
GeneOntologyBiologicalProcess	protein localization to cell junction	ZDHHC2 ZDHHC7 WNT7A	1.04e-03	148	28	3	GO:1902414
GeneOntologyBiologicalProcess	embryonic forelimb morphogenesis	MECOM WNT7A	1.15e-03	37	28	2	GO:0035115
GeneOntologyBiologicalProcess	anterograde trans-synaptic signaling	ZDHHC2 UNC13B UNC13C ZZEF1 UNC13A WNT7A	1.33e-03	931	28	6	GO:0098916
GeneOntologyBiologicalProcess	chemical synaptic transmission	ZDHHC2 UNC13B UNC13C ZZEF1 UNC13A WNT7A	1.33e-03	931	28	6	GO:0007268
GeneOntologyBiologicalProcess	trans-synaptic signaling	ZDHHC2 UNC13B UNC13C ZZEF1 UNC13A WNT7A	1.39e-03	939	28	6	GO:0099537
GeneOntologyBiologicalProcess	synaptic signaling	ZDHHC2 UNC13B UNC13C ZZEF1 UNC13A WNT7A	1.70e-03	976	28	6	GO:0099536
GeneOntologyBiologicalProcess	forelimb morphogenesis	MECOM WNT7A	1.93e-03	48	28	2	GO:0035136
GeneOntologyBiologicalProcess	appendage morphogenesis	PCSK5 MECOM WNT7A	1.97e-03	185	28	3	GO:0035107
GeneOntologyBiologicalProcess	limb morphogenesis	PCSK5 MECOM WNT7A	1.97e-03	185	28	3	GO:0035108
GeneOntologyBiologicalProcess	hindlimb morphogenesis	MECOM WNT7A	2.01e-03	49	28	2	GO:0035137
GeneOntologyBiologicalProcess	cell fate determination	EBF2 WNT7A	2.09e-03	50	28	2	GO:0001709
GeneOntologyBiologicalProcess	peptidyl-cysteine modification	ZDHHC2 ZDHHC7	2.09e-03	50	28	2	GO:0018198
GeneOntologyBiologicalProcess	exocytosis	UNC13B UNC13C UNC13A WNT7A	2.65e-03	434	28	4	GO:0006887
GeneOntologyBiologicalProcess	regulation of synaptic vesicle exocytosis	UNC13B WNT7A	3.20e-03	62	28	2	GO:2000300
GeneOntologyBiologicalProcess	establishment of vesicle localization	UNC13B UNC13C UNC13A	3.39e-03	224	28	3	GO:0051650
GeneOntologyBiologicalProcess	limb development	PCSK5 MECOM WNT7A	3.39e-03	224	28	3	GO:0060173
GeneOntologyBiologicalProcess	appendage development	PCSK5 MECOM WNT7A	3.39e-03	224	28	3	GO:0048736
GeneOntologyBiologicalProcess	brown fat cell differentiation	EBF2 MECOM	3.72e-03	67	28	2	GO:0050873
GeneOntologyBiologicalProcess	neuromuscular junction development	UNC13B UNC13A	3.83e-03	68	28	2	GO:0007528
GeneOntologyCellularComponent	presynaptic active zone cytoplasmic component	UNC13B UNC13C UNC13A	3.74e-06	23	28	3	GO:0098831
GeneOntologyCellularComponent	calyx of Held	UNC13B UNC13C UNC13A	1.49e-05	36	28	3	GO:0044305
GeneOntologyCellularComponent	cell cortex region	UNC13B UNC13C UNC13A	2.94e-05	45	28	3	GO:0099738
GeneOntologyCellularComponent	presynaptic active zone	UNC13B UNC13C ZZEF1 UNC13A	3.58e-05	141	28	4	GO:0048786
GeneOntologyCellularComponent	terminal bouton	UNC13B UNC13C UNC13A	2.83e-04	96	28	3	GO:0043195
GeneOntologyCellularComponent	Golgi lumen	PCSK5 HSPG2 WNT7A	4.11e-04	109	28	3	GO:0005796
GeneOntologyCellularComponent	neuromuscular junction	UNC13B UNC13C UNC13A	4.45e-04	112	28	3	GO:0031594
GeneOntologyCellularComponent	presynaptic membrane	UNC13B UNC13C ADAM11 UNC13A	4.81e-04	277	28	4	GO:0042734
GeneOntologyCellularComponent	presynapse	UNC13B UNC13C ADAM11 ZZEF1 UNC13A WNT7A	9.64e-04	886	28	6	GO:0098793
GeneOntologyCellularComponent	cytoplasmic region	UNC13B UNC13C SAXO1 UNC13A	1.28e-03	360	28	4	GO:0099568
GeneOntologyCellularComponent	cytoplasmic vesicle membrane	ZDHHC2 UNC13B UNC13C RFFL RBSN UNC13A WNT7A	1.36e-03	1307	28	7	GO:0030659
GeneOntologyCellularComponent	cell cortex	UNC13B UNC13C MYO9B UNC13A	1.43e-03	371	28	4	GO:0005938
GeneOntologyCellularComponent	vesicle membrane	ZDHHC2 UNC13B UNC13C RFFL RBSN UNC13A WNT7A	1.47e-03	1325	28	7	GO:0012506
GeneOntologyCellularComponent	exocytic vesicle membrane	UNC13B UNC13C UNC13A	1.73e-03	179	28	3	GO:0099501
GeneOntologyCellularComponent	synaptic vesicle membrane	UNC13B UNC13C UNC13A	1.73e-03	179	28	3	GO:0030672
GeneOntologyCellularComponent	axon terminus	UNC13B UNC13C UNC13A	2.72e-03	210	28	3	GO:0043679
GeneOntologyCellularComponent	neuron projection terminus	UNC13B UNC13C UNC13A	3.65e-03	233	28	3	GO:0044306
Domain	Unc-13	UNC13B UNC13C UNC13A	3.02e-09	3	28	3	IPR027080
Domain	Transcription_factor_COE	EBF2 EBF1 EBF3	1.21e-08	4	28	3	IPR003523
Domain	COE1_HLH	EBF2 EBF1 EBF3	1.21e-08	4	28	3	PF16423
Domain	COE1_DBD	EBF2 EBF1 EBF3	1.21e-08	4	28	3	PF16422
Domain	COE_HLH	EBF2 EBF1 EBF3	1.21e-08	4	28	3	IPR032201
Domain	COE_DBD	EBF2 EBF1 EBF3	1.21e-08	4	28	3	IPR032200
Domain	COE	EBF2 EBF1 EBF3	1.21e-08	4	28	3	PS01345
Domain	Transcription_factor_COE_CS	EBF2 EBF1 EBF3	1.21e-08	4	28	3	IPR018350
Domain	C1_1	UNC13B UNC13C CIT MYO9B UNC13A	2.06e-08	57	28	5	PF00130
Domain	Munc13_dom-2	UNC13B UNC13C UNC13A	3.01e-08	5	28	3	IPR014772
Domain	Membr_traf_MHD	UNC13B UNC13C UNC13A	3.01e-08	5	28	3	PF10540
Domain	DUF1041	UNC13B UNC13C UNC13A	3.01e-08	5	28	3	SM01145
Domain	MHD2	UNC13B UNC13C UNC13A	3.01e-08	5	28	3	PS51259
Domain	Munc13_subgr_dom-2	UNC13B UNC13C UNC13A	3.01e-08	5	28	3	IPR019558
Domain	ZF_DAG_PE_1	UNC13B UNC13C CIT MYO9B UNC13A	3.73e-08	64	28	5	PS00479
Domain	ZF_DAG_PE_2	UNC13B UNC13C CIT MYO9B UNC13A	3.73e-08	64	28	5	PS50081
Domain	C1	UNC13B UNC13C CIT MYO9B UNC13A	4.03e-08	65	28	5	SM00109
Domain	PE/DAG-bd	UNC13B UNC13C CIT MYO9B UNC13A	4.36e-08	66	28	5	IPR002219
Domain	DUF1041	UNC13B UNC13C UNC13A	1.05e-07	7	28	3	PF06292
Domain	Munc13_1	UNC13B UNC13C UNC13A	1.05e-07	7	28	3	IPR014770
Domain	CAPS_dom	UNC13B UNC13C UNC13A	1.05e-07	7	28	3	IPR010439
Domain	MHD1	UNC13B UNC13C UNC13A	1.05e-07	7	28	3	PS51258
Domain	zf-DHHC	ZDHHC2 ZDHHC7 ZDHHC16	5.24e-06	23	28	3	PF01529
Domain	DHHC	ZDHHC2 ZDHHC7 ZDHHC16	6.79e-06	25	28	3	PS50216
Domain	Znf_DHHC_palmitoyltrfase	ZDHHC2 ZDHHC7 ZDHHC16	6.79e-06	25	28	3	IPR001594
Domain	IPT	EBF2 EBF1 EBF3	8.62e-06	27	28	3	SM00429
Domain	TIG	EBF2 EBF1 EBF3	1.32e-05	31	28	3	PF01833
Domain	IPT	EBF2 EBF1 EBF3	1.45e-05	32	28	3	IPR002909
Domain	Furin_repeat	PCSK5 RSPO1	3.27e-04	18	28	2	IPR006212
Domain	FU	PCSK5 RSPO1	3.27e-04	18	28	2	SM00261
Domain	Ig_E-set	EBF2 EBF1 EBF3	4.97e-04	104	28	3	IPR014756
Domain	HLH	EBF2 EBF1 EBF3	6.83e-04	116	28	3	SM00353
Domain	C2	UNC13B UNC13C UNC13A	9.72e-04	131	28	3	PF00168
Domain	C2	UNC13B UNC13C UNC13A	1.11e-03	137	28	3	SM00239
Domain	C2	UNC13B UNC13C UNC13A	1.23e-03	142	28	3	PS50004
Domain	-	UNC13B UNC13C UNC13A	1.38e-03	148	28	3	2.60.40.150
Domain	Znf_FYVE	RFFL RBSN	1.47e-03	38	28	2	IPR000306
Domain	Growth_fac_rcpt_	PCSK5 HSPG2 RSPO1	1.61e-03	156	28	3	IPR009030
Domain	ZF_FYVE	RFFL RBSN	1.63e-03	40	28	2	PS50178
Domain	C2_dom	UNC13B UNC13C UNC13A	1.85e-03	164	28	3	IPR000008
Domain	-	RFFL RBSN RNF183 RNF2	4.27e-03	449	28	4	3.30.40.10
Domain	Znf_RING/FYVE/PHD	RFFL RBSN RNF183 RNF2	4.62e-03	459	28	4	IPR013083
Domain	EGF	PCSK5 HSPG2 ADAM11	5.11e-03	235	28	3	SM00181
Domain	-	PCSK5 ZZEF1	5.33e-03	73	28	2	2.60.120.260
Domain	EGF-like_dom	PCSK5 HSPG2 ADAM11	6.00e-03	249	28	3	IPR000742
Domain	Galactose-bd-like	PCSK5 ZZEF1	8.70e-03	94	28	2	IPR008979
Domain	ZF_RING_1	RFFL RNF183 RNF2	9.19e-03	291	28	3	PS00518
Domain	ZF_RING_2	RFFL RNF183 RNF2	9.81e-03	298	28	3	PS50089
Domain	RING	RFFL RNF183 RNF2	1.04e-02	305	28	3	SM00184
Domain	Znf_RING	RFFL RNF183 RNF2	1.25e-02	326	28	3	IPR001841
Domain	-	EBF2 HSPG2 EBF1 EBF3	1.64e-02	663	28	4	2.60.40.10
Pathway	WP_SYNAPTIC_VESICLE_PATHWAY	UNC13B UNC13C UNC13A	5.67e-05	51	21	3	M39457
Pathway	WP_16P112_PROXIMAL_DELETION_SYNDROME	UNC13B PPP4R1 UNC13A	1.87e-04	76	21	3	M40057
Pubmed	Heterogeneous Presynaptic Distribution of Munc13 Isoforms at Retinal Synapses and Identification of an Unconventional Bipolar Cell Type with Dual Expression of Munc13 Isoforms: A Study Using Munc13-EXFP Knock-in Mice.	UNC13B UNC13C UNC13A	4.67e-10	3	28	3	33105896
Pubmed	The characterization of the Olf-1/EBF-like HLH transcription factor family: implications in olfactory gene regulation and neuronal development.	EBF2 EBF1 EBF3	4.67e-10	3	28	3	9151732
Pubmed	Nonconserved Ca(2+)/calmodulin binding sites in Munc13s differentially control synaptic short-term plasticity.	UNC13B UNC13C UNC13A	4.67e-10	3	28	3	22966208
Pubmed	The Munc13 proteins differentially regulate readily releasable pool dynamics and calcium-dependent recovery at a central synapse.	UNC13B UNC13C UNC13A	4.67e-10	3	28	3	23658173
Pubmed	Aberrant morphology and residual transmitter release at the Munc13-deficient mouse neuromuscular synapse.	UNC13B UNC13C UNC13A	4.67e-10	3	28	3	15988013
Pubmed	Cloning of a novel Olf-1/EBF-like gene, O/E-4, by degenerate oligo-based direct selection.	EBF2 EBF1 EBF3	1.87e-09	4	28	3	12139918
Pubmed	Cloning and functional characterization of Roaz, a zinc finger protein that interacts with O/E-1 to regulate gene expression: implications for olfactory neuronal development.	EBF2 EBF1 EBF3	1.87e-09	4	28	3	9151733
Pubmed	An active vesicle priming machinery suppresses axon regeneration upon adult CNS injury.	UNC13B UNC13C UNC13A	4.67e-09	5	28	3	34706221
Pubmed	Identification of a Munc13-sensitive step in chromaffin cell large dense-core vesicle exocytosis.	UNC13B UNC13C UNC13A	4.67e-09	5	28	3	26575293
Pubmed	Expression patterns of the coe/ebf transcription factor genes during chicken and mouse limb development.	EBF2 EBF1 EBF3	4.67e-09	5	28	3	15261831
Pubmed	Formation of whisker-related principal sensory nucleus-based lemniscal pathway requires a paired homeodomain transcription factor, Drg11.	EBF2 EBF1 EBF3	4.67e-09	5	28	3	12917357
Pubmed	Family of Ebf/Olf-1-related genes potentially involved in neuronal differentiation and regional specification in the central nervous system.	EBF2 EBF1 EBF3	9.33e-09	6	28	3	9389446
Pubmed	Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1.	EBF2 EBF1 EBF3	1.63e-08	7	28	3	24786561
Pubmed	Munc13 supports fusogenicity of non-docked vesicles at synapses with disrupted active zones.	UNC13B UNC13C UNC13A	1.63e-08	7	28	3	36398873
Pubmed	Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.	UNC13B UNC13C UNC13A	2.61e-08	8	28	3	25609709
Pubmed	Genetic disruptions of O/E2 and O/E3 genes reveal involvement in olfactory receptor neuron projection.	EBF2 EBF1 EBF3	2.61e-08	8	28	3	14993187
Pubmed	Molecular and functional architecture of striatal dopamine release sites.	UNC13B UNC13C UNC13A	7.68e-08	11	28	3	34767769
Pubmed	Control of hindbrain motor neuron differentiation by the homeobox gene Phox2b.	EBF2 EBF1 EBF3	7.68e-08	11	28	3	10704382
Pubmed	An ancient role for collier/Olf/Ebf (COE)-type transcription factors in axial motor neuron development.	EBF2 EBF1 EBF3	1.02e-07	12	28	3	30658714
Pubmed	Transient and lineage-restricted requirement of Ebf3 for sternum ossification.	EBF2 EBF1 EBF3	1.02e-07	12	28	3	32398354
Pubmed	Control of the migratory pathway of facial branchiomotor neurones.	EBF2 EBF1 EBF3	1.33e-07	13	28	3	11076752
Pubmed	Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem.	EBF2 EBF1 EBF3	1.33e-07	13	28	3	22421355
Pubmed	Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse.	EBF2 EBF1 EBF3	2.11e-07	15	28	3	25762221
Pubmed	Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system.	ZDHHC2 ZDHHC7 ZDHHC16	2.60e-07	16	28	3	23034182
Pubmed	The Transcription Factors EBF1 and EBF2 Are Positive Regulators of Myelination in Schwann Cells.	EBF2 EBF1 EBF3	3.15e-07	17	28	3	27889898
Pubmed	A key role for the HLH transcription factor EBF2COE2,O/E-3 in Purkinje neuron migration and cerebellar cortical topography.	EBF2 EBF1 EBF3	5.28e-07	20	28	3	16774995
Pubmed	The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways.	EBF2 EBF1 EBF3	6.15e-07	21	28	3	27600842
Pubmed	Calcium-Independent Exo-endocytosis Coupling at Small Central Synapses.	UNC13B UNC13A	6.25e-07	2	28	2	31851910
Pubmed	Early B Cell Factor Activity Controls Developmental and Adaptive Thermogenic Gene Programming in Adipocytes.	EBF2 EBF1	6.25e-07	2	28	2	32130892
Pubmed	Formation and Maintenance of Functional Spines in the Absence of Presynaptic Glutamate Release.	UNC13B UNC13A	6.25e-07	2	28	2	28426965
Pubmed	Heterodimerization of Munc13 C2A domain with RIM regulates synaptic vesicle docking and priming.	UNC13B UNC13A	6.25e-07	2	28	2	28489077
Pubmed	A fluorescent nanosensor paint detects dopamine release at axonal varicosities with high spatiotemporal resolution.	UNC13B UNC13A	6.25e-07	2	28	2	35613050
Pubmed	Differential control of vesicle priming and short-term plasticity by Munc13 isoforms.	UNC13B UNC13A	6.25e-07	2	28	2	11832228
Pubmed	Dynamic control of synaptic vesicle replenishment and short-term plasticity by Ca(2+)-calmodulin-Munc13-1 signaling.	UNC13B UNC13A	6.25e-07	2	28	2	23770256
Pubmed	Munc13-1 is essential for fusion competence of glutamatergic synaptic vesicles.	UNC13B UNC13A	6.25e-07	2	28	2	10440375
Pubmed	Inhibition of exocytosis or endocytosis blocks activity-dependent redistribution of synapsin.	UNC13B UNC13A	6.25e-07	2	28	2	22066784
Pubmed	Membrane bridging by Munc13-1 is crucial for neurotransmitter release.	UNC13B UNC13A	6.25e-07	2	28	2	30816091
Pubmed	Munc13 controls the location and efficiency of dense-core vesicle release in neurons.	UNC13B UNC13A	6.25e-07	2	28	2	23229896
Pubmed	Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses.	UNC13B UNC13A	6.25e-07	2	28	2	32187536
Pubmed	Total arrest of spontaneous and evoked synaptic transmission but normal synaptogenesis in the absence of Munc13-mediated vesicle priming.	UNC13B UNC13A	6.25e-07	2	28	2	12070347
Pubmed	Beta phorbol ester- and diacylglycerol-induced augmentation of transmitter release is mediated by Munc13s and not by PKCs.	UNC13B UNC13A	6.25e-07	2	28	2	11792326
Pubmed	Critical role for Ebf1 and Ebf2 in the adipogenic transcriptional cascade.	EBF2 EBF1	6.25e-07	2	28	2	17060461
Pubmed	Munc13-independent vesicle priming at mouse photoreceptor ribbon synapses.	UNC13B UNC13C	6.25e-07	2	28	2	22674279
Pubmed	Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.	UNC13B UNC13A	6.25e-07	2	28	2	28772123
Pubmed	A common molecular basis for membrane docking and functional priming of synaptic vesicles.	UNC13B UNC13A	6.25e-07	2	28	2	19558619
Pubmed	Regulation of insulin exocytosis by Munc13-1.	UNC13B UNC13A	6.25e-07	2	28	2	12871971
Pubmed	Phorbol esters modulate spontaneous and Ca2+-evoked transmitter release via acting on both Munc13 and protein kinase C.	UNC13B UNC13A	6.25e-07	2	28	2	18701688
Pubmed	Munc13-1 C1 domain activation lowers the energy barrier for synaptic vesicle fusion.	UNC13B UNC13A	6.25e-07	2	28	2	17267576
Pubmed	Formation of perineuronal nets in organotypic mouse brain slice cultures is independent of neuronal glutamatergic activity.	UNC13B UNC13A	6.25e-07	2	28	2	17561838
Pubmed	Role of mammalian homologue of Caenorhabditis elegans unc-13-1 (Munc13-1) in the recruitment of newcomer insulin granules in both first and second phases of glucose-stimulated insulin secretion in mouse islets.	UNC13B UNC13A	6.25e-07	2	28	2	22814762
Pubmed	Munc13 genotype regulates secretory amyloid precursor protein processing via postsynaptic glutamate receptors.	UNC13B UNC13A	6.25e-07	2	28	2	23070049
Pubmed	Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors.	EBF2 EBF1 EBF3	9.35e-07	24	28	3	20826655
Pubmed	Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord.	EBF2 EBF1 EBF3	1.06e-06	25	28	3	15229182
Pubmed	Redundant functions of RIM1alpha and RIM2alpha in Ca(2+)-triggered neurotransmitter release.	UNC13B UNC13C UNC13A	1.20e-06	26	28	3	17124501
Pubmed	Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons.	EBF2 EBF1 EBF3	1.35e-06	27	28	3	33760820
Pubmed	EBF2 determines and maintains brown adipocyte identity.	EBF2 EBF1 EBF3	1.68e-06	29	28	3	23499423
Pubmed	Multimodal Hox5 activity generates motor neuron diversity.	EBF2 EBF1 EBF3	1.68e-06	29	28	3	39289460
Pubmed	Munc13- and SNAP25-dependent molecular bridges play a key role in synaptic vesicle priming.	UNC13B UNC13A	1.87e-06	3	28	2	37343100
Pubmed	Aph2, a protein with a zf-DHHC motif, interacts with c-Abl and has pro-apoptotic activity.	ZDHHC2 ZDHHC16	1.87e-06	3	28	2	12021275
Pubmed	Interaction between Munc13-1 and RIM is critical for glucagon-like peptide-1 mediated rescue of exocytotic defects in Munc13-1 deficient pancreatic beta-cells.	UNC13B UNC13A	1.87e-06	3	28	2	17639022
Pubmed	Age-Progressive and Gender-Dependent Bone Phenotype in Mice Lacking Both Ebf1 and Ebf2 in Prrx1-Expressing Mesenchymal Cells.	EBF2 EBF1	1.87e-06	3	28	2	35137272
Pubmed	The synaptic vesicle cycle.	UNC13B UNC13C UNC13A	2.07e-06	31	28	3	15217342
Pubmed	Transient, phorbol ester-induced DOC2-Munc13 interactions in vivo.	UNC13B UNC13A	3.75e-06	4	28	2	10488064
Pubmed	Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.	UNC13B UNC13A	3.75e-06	4	28	2	19996097
Pubmed	Munc13-1-mediated vesicle priming contributes to secretory amyloid precursor protein processing.	UNC13B UNC13A	3.75e-06	4	28	2	15123597
Pubmed	ELKS1 localizes the synaptic vesicle priming protein bMunc13-2 to a specific subset of active zones.	UNC13B UNC13A	3.75e-06	4	28	2	28264913
Pubmed	RIM, Munc13, and Rab3A interplay in acrosomal exocytosis.	UNC13B UNC13A	6.24e-06	5	28	2	22248876
Pubmed	Stem cell niche-specific Ebf3 maintains the bone marrow cavity.	EBF1 EBF3	6.24e-06	5	28	2	29563184
Pubmed	Molecular basis of fatty acid selectivity in the zDHHC family of S-acyltransferases revealed by click chemistry.	ZDHHC2 ZDHHC7	6.24e-06	5	28	2	28167757
Pubmed	A Trio of Active Zone Proteins Comprised of RIM-BPs, RIMs, and Munc13s Governs Neurotransmitter Release.	UNC13B UNC13A	6.24e-06	5	28	2	32755572
Pubmed	Disentangling the Roles of RIM and Munc13 in Synaptic Vesicle Localization and Neurotransmission.	UNC13B UNC13A	6.24e-06	5	28	2	33139401
Pubmed	The transcription factor, Lmx1b, is necessary for the development of the principal trigeminal nucleus-based lemniscal pathway.	EBF1 EBF3	9.36e-06	6	28	2	20621716
Pubmed	Munc13-1 and Munc18-1 together prevent NSF-dependent de-priming of synaptic vesicles.	UNC13B UNC13A	9.36e-06	6	28	2	28635948
Pubmed	SNAREs and traffic.	UNC13B UNC13A	1.31e-05	7	28	2	15893389
Pubmed	TWIST1 Homodimers and Heterodimers Orchestrate Lineage-Specific Differentiation.	EBF1 EBF3	1.74e-05	8	28	2	32179550
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	UNC13B PCSK5 ZDHHC7 HSPG2 ZZEF1 CIT MYO9B	2.11e-05	1105	28	7	35748872
Pubmed	SNARE protein recycling by αSNAP and βSNAP supports synaptic vesicle priming.	UNC13B UNC13A	2.80e-05	10	28	2	21040848
Pubmed	A POU domain transcription factor-dependent program regulates axon pathfinding in the vertebrate visual system.	EBF1 EBF3	2.80e-05	10	28	2	11163266
Pubmed	The morphological and molecular nature of synaptic vesicle priming at presynaptic active zones.	UNC13B UNC13A	3.42e-05	11	28	2	25374362
Pubmed	Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling.	EBF1 EBF3	7.45e-05	16	28	2	17444492
Pubmed	Control of neuronal morphology by the atypical cadherin Fat3.	EBF2 EBF3	7.45e-05	16	28	2	21903076
Pubmed	Identification of PSD-95 palmitoylating enzymes.	ZDHHC2 ZDHHC7	8.44e-05	17	28	2	15603741
Pubmed	The paired homeodomain protein DRG11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord.	EBF2 EBF1	1.06e-04	19	28	2	11498051
Pubmed	Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.	ZDHHC2 ZDHHC7	1.18e-04	20	28	2	16647879
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	EBF1 RNF2 CIT ZDHHC16	1.24e-04	322	28	4	26514267
Pubmed	Age of onset of amyotrophic lateral sclerosis is modulated by a locus on 1p34.1.	PCSK5 UNC13A	1.30e-04	21	28	2	22959728
Pubmed	Neonatal Wnt-dependent Lgr5 positive stem cells are essential for uterine gland development.	RSPO1 WNT7A	1.71e-04	24	28	2	31772170
Pubmed	Emx2 directs the development of diencephalon in cooperation with Otx2.	EBF1 EBF3	1.71e-04	24	28	2	11493561
Pubmed	Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons.	EBF1 EBF3	2.33e-04	28	28	2	30796806
Pubmed	Identification of Arx transcriptional targets in the developing basal forebrain.	EBF1 EBF3	2.33e-04	28	28	2	18799476
Pubmed	Wnt5a potentiates TGF-β signaling to promote colonic crypt regeneration after tissue injury.	RSPO1 WNT7A	2.50e-04	29	28	2	22956684
Pubmed	Defining the lineage of thermogenic perivascular adipose tissue.	EBF2 EBF1	2.50e-04	29	28	2	33846639
Pubmed	Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk.	MECOM EBF1	2.50e-04	29	28	2	21909115
Pubmed	Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.	EBF1 EBF3	2.68e-04	30	28	2	30127719
Pubmed	Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia.	RSPO1 WNT7A	2.68e-04	30	28	2	19282366
Pubmed	Atlas of Wnt and R-spondin gene expression in the developing male mouse lower urogenital tract.	RSPO1 WNT7A	2.68e-04	30	28	2	21936019
Pubmed	c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections.	EBF2 EBF1	3.05e-04	32	28	2	22514301
Pubmed	Single-cell transcriptomic analysis reveals diversity within mammalian spinal motor neurons.	EBF2 MECOM	3.05e-04	32	28	2	36596814
Pubmed	Single-cell transcriptomic analysis of mouse neocortical development.	EBF1 EBF3 RSPO1	3.44e-04	170	28	3	30635555
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	PCSK5 ZDHHC7 MECOM ADAM11 USP54 MYO9B	3.49e-04	1215	28	6	15146197
GeneFamily	UNC13 homologs	UNC13B UNC13C UNC13A	5.40e-09	4	21	3	836
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC2 ZDHHC7 ZDHHC16	2.69e-06	24	21	3	76
GeneFamily	Ring finger proteins	RFFL RNF183 RNF2	3.78e-03	275	21	3	58
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	ZDHHC2 UNC13B EBF2 MECOM RFFL CIT RSPO1 WNT7A	2.91e-05	989	28	8	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	dev gonad_e12.5_F_DevVasOvary_Flk_top-relative-expression-ranked_200	MECOM HSPG2 EBF1 EBF3	7.99e-05	176	28	4	gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_200
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#4_top-relative-expression-ranked_200	EBF2 EBF1 EBF3	9.72e-05	68	28	3	gudmap_developingKidney_e13.5_podocyte cells_200_k4
CoexpressionAtlas	dev gonad_e12.5_F_DevVasOvary_Flk_k-means-cluster#4_top-relative-expression-ranked_200	HSPG2 EBF1 EBF3	2.09e-04	88	28	3	gudmap_dev gonad_e12.5_F_gudmap_devVasOvary_Flk_k4_200
CoexpressionAtlas	dev gonad_e11.5_M_ReproVasc_Flk_k-means-cluster#3_top-relative-expression-ranked_500	MECOM HSPG2 EBF1 EBF3	2.09e-04	226	28	4	gudmap_dev gonad_e11.5_M_ReproVasc_Flk_k3_500
CoexpressionAtlas	dev gonad_e11.5_F_ReproVasc_Flk_k-means-cluster#4_top-relative-expression-ranked_500	MECOM HSPG2 EBF1 EBF3	2.20e-04	229	28	4	gudmap_dev gonad_e11.5_F_ReproVasc_Flk_k4_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#4	ZDHHC2 EBF2 RFFL WNT7A	2.28e-04	231	28	4	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K4
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_100	EBF2 MECOM EBF3	2.79e-04	97	28	3	Facebase_RNAseq_e9.5_Maxillary Arch_100
CoexpressionAtlas	DevelopingKidney_e11.5_metaneph mesench_emap-3843_k-means-cluster#3_top-relative-expression-ranked_200	EBF2 EBF3	3.14e-04	20	28	2	gudmap_developingKidney_e11.5_metaneph mesench_200_k3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500_k-means-cluster#1	EBF2 MECOM EBF3	3.42e-04	104	28	3	Facebase_RNAseq_e10.5_Olfactory Pit_500_K1
CoexpressionAtlas	dev gonad_e13.5_F_DevVascOvary_Flk_k-means-cluster#2_top-relative-expression-ranked_200	MECOM EBF1 EBF3	4.03e-04	110	28	3	gudmap_dev gonad_e13.5_F_gudmap_devVascOvary_Flk_k2_200
CoexpressionAtlas	FacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_500	ZDHHC2 UNC13B EBF2 MECOM EBF3	4.25e-04	495	28	5	Facebase_RNAseq_e10.5_Olfactory Pit_500
CoexpressionAtlas	dev gonad_e11.5_F_ReproVasc_Flk_k-means-cluster#3_top-relative-expression-ranked_200	MECOM EBF1 EBF3	4.71e-04	116	28	3	gudmap_dev gonad_e11.5_F_ReproVasc_Flk_k3_200
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#5	EBF2 EBF1 EBF3	4.71e-04	116	28	3	ratio_EB_vs_SC_500_K5
CoexpressionAtlas	dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#4_top-relative-expression-ranked_500	MECOM HSPG2 EBF1 EBF3	4.85e-04	282	28	4	gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k4_500
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000	PCSK5 EBF1 FAM174A EBF3	5.25e-04	288	28	4	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5
CoexpressionAtlas	dev gonad_e13.5_M_DevVasTestis_Flk_k-means-cluster#2_top-relative-expression-ranked_200	MECOM EBF1 EBF3	5.59e-04	123	28	3	gudmap_dev gonad_e13.5_M_gudmap_devVasTestis_Flk_k2_200
CoexpressionAtlas	dev gonad_e12.5_M_DevVasTestis_Flk_k-means-cluster#2_top-relative-expression-ranked_500	MECOM HSPG2 EBF1 EBF3	5.97e-04	298	28	4	gudmap_dev gonad_e12.5_M_gudmap_devVasTestis_Flk_k2_500
CoexpressionAtlas	kidney_P0_JuxtaGlom_Ren1_k-means-cluster#3_top-relative-expression-ranked_100	MECOM EBF1	6.21e-04	28	28	2	gudmap_kidney_P0_JuxtaGlom_Ren1_k3_100
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_100	EBF1 EBF3	6.21e-04	28	28	2	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_100_k3
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	ZDHHC2 RFFL RBSN CIT RSPO1 WNT7A	6.35e-04	831	28	6	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#1_top-relative-expression-ranked_100	EBF2 EBF3	7.61e-04	31	28	2	gudmap_developingKidney_e13.5_podocyte cells_100_k1
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_500_k-means-cluster#1	EBF2 MECOM EBF3	7.65e-04	137	28	3	Facebase_RNAseq_e10.5_Mandibular Arch_500_K1
CoexpressionAtlas	DevelopingKidney_e13.5_podocyte cells_emap-27773_k-means-cluster#1_top-relative-expression-ranked_500	EBF2 EBF1 EBF3	8.49e-04	142	28	3	gudmap_developingKidney_e13.5_podocyte cells_500_k1
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#1	EBF2 MECOM EBF1 EBF3	9.34e-04	336	28	4	ratio_EB_vs_SC_1000_K1
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#4_top-relative-expression-ranked_1000	EBF2 EBF1 EBF3	1.01e-03	151	28	3	gudmap_developingLowerUrinaryTract_P1_ureter_1000_k4
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCSK5 MECOM HSPG2 EBF1 EBF3	7.47e-08	174	28	5	18ab52d8bbca0507fee220e0c4fc765fc47dda34
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EBF2 MECOM HSPG2 EBF1 EBF3	9.34e-08	182	28	5	fbd5e332df73bf7141c822fa67b76367dc962017
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Adult / Lineage, Cell type, age group and donor	UNC13B MECOM UNC13C USP54 CIT	1.01e-07	185	28	5	673f0c688ae6984bc8027df2da335787924f4137
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	UNC13B MECOM USP54 CIT	3.75e-06	170	28	4	a2c738e441ced90eeeb1fcc6ca3269b918aaa298
ToppCell	wk_15-18-Epithelial-Distal_epithelial-type_I_pneumocyte\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	UNC13B MECOM HSPG2 WNT7A	4.12e-06	174	28	4	2cd6638b361ca05ab83d09ce657194aed97873b7
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122\|Adult / Lineage, Cell type, age group and donor	MECOM UNC13C USP54 CIT	4.31e-06	176	28	4	3fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	UNC13B MECOM USP54 CIT	4.60e-06	179	28	4	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	UNC13B MECOM USP54 CIT	4.81e-06	181	28	4	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	COVID-19-Heart-EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EBF2 MECOM EBF1 EBF3	4.92e-06	182	28	4	e67f3234165199085c793915ebb1f9bbd845e933
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MECOM UNC13C USP54 CIT	5.13e-06	184	28	4	102105ae1a5ef6d42a43f6d9b00f12ed0690ddb7
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	UNC13B MECOM USP54 CIT	5.24e-06	185	28	4	98b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	UNC13B MECOM USP54 CIT	5.36e-06	186	28	4	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	UNC13B HSPG2 USP54 WNT7A	5.47e-06	187	28	4	4ae7465174e0295d2c3b614b321a3b2f514dd22a
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	UNC13B MECOM USP54 CIT	5.47e-06	187	28	4	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 EBF1 EBF3 RSPO1	5.59e-06	188	28	4	ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	UNC13B PPP4R1 MECOM USP54	5.59e-06	188	28	4	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PCSK5 HSPG2 EBF1 EBF3	5.71e-06	189	28	4	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	COVID-19-Heart-EC_(POSTN)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MECOM HSPG2 UNC13C EBF1	5.71e-06	189	28	4	7346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCell	COVID-19-Heart-EC_1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MECOM HSPG2 EBF1 EBF3	5.71e-06	189	28	4	fe49852ba15f948b384d6b4c258927c70b741357
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 EBF1 EBF3 RSPO1	5.83e-06	190	28	4	efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCSK5 MECOM HSPG2 EBF3	5.95e-06	191	28	4	04c7aa2e39fdd08ca24c10d43b29a5e41a73b9e0
ToppCell	3'-Broncho-tracheal-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCSK5 MECOM HSPG2 EBF3	5.95e-06	191	28	4	db8dd6bbba803585bdd6a55d5c403d383f2e9acf
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	EBF2 PCSK5 MECOM EBF1	6.07e-06	192	28	4	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	EBF2 MECOM EBF1 EBF3	6.07e-06	192	28	4	d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	UNC13B MECOM USP54 CIT	6.33e-06	194	28	4	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	EBF2 PCSK5 MECOM EBF1	6.33e-06	194	28	4	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	EBF2 PCSK5 MECOM EBF1	6.33e-06	194	28	4	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EBF2 PCSK5 EBF1 EBF3	7.00e-06	199	28	4	1fd7bbb8727607e6507848602a19bc86882ef2d5
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Neuron\|5w / Sample Type, Dataset, Time_group, and Cell type.	EBF2 EBF1 ZZEF1 EBF3	7.14e-06	200	28	4	6f3fe94107fa2a2ded4888780b36700cce48adb7
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Necab1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PCSK5 UNC13C WNT7A	6.67e-05	126	28	3	a4fc7ac4931d2fc8aa8196a62d809b698937aa9c
ToppCell	TCGA-Bone_and_Soft_Tissue\|World / Sample_Type by Project: Shred V9	EBF2 EBF1 EBF3	8.01e-05	134	28	3	9940a710a5d6670244cce5e19f88b4195a59875b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 EBF1 EBF3	8.93e-05	139	28	3	b07929348ec9ad95d7bce33a7deac0938227b19f
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CIT RSPO1 WNT7A	1.01e-04	145	28	3	78f5f4b96420c7f391e4d32a9ed151ed95fad90b
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|367C / Donor, Lineage, Cell class and subclass (all cells)	ZDHHC2 RFFL ZZEF1	1.10e-04	149	28	3	41f28138bde45d0b814e116837e5a32b5e80d54a
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EBF1 EBF3 UNC13A	1.12e-04	150	28	3	1270f33f9d7e46e55adf1a96e8beee858b95589d
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-NP\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	UNC13B PCSK5 UNC13C	1.12e-04	150	28	3	2ba55e51877e2e749cccdae7df5d885dc55b2587
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EBF1 EBF3 UNC13A	1.12e-04	150	28	3	156118ce1d69522624196410cba18b8354cd0bb4
ToppCell	LPS-IL1RA-Myeloid_granulocytic-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	UNC13C RFFL RBSN	1.21e-04	154	28	3	43735f7c58cac51855ded486ee8d8729a1b9909e
ToppCell	LPS-IL1RA-Myeloid_granulocytic\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	UNC13C RFFL RBSN	1.21e-04	154	28	3	d55fb73461885e1e02061a344ff89624ef4de487
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Rspo4_Rxfp1_Chat\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CIT RSPO1 WNT7A	1.23e-04	155	28	3	3b8def9e8f66511736ea37f259511f7c8b7743af
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122\|Adult / Lineage, Cell type, age group and donor	UNC13B MECOM CIT	1.28e-04	157	28	3	31d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B PCSK5 UNC13C	1.31e-04	158	28	3	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B PCSK5 UNC13C	1.31e-04	158	28	3	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	UNC13B MECOM CIT	1.33e-04	159	28	3	e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 EBF1 EBF3	1.38e-04	161	28	3	a006491c991e6a134be20ad75092a91f3b7c3c91
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 EBF1 EBF3	1.38e-04	161	28	3	4f25eeabb841b0b9204cdd4e71d5e131e7868184
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	UNC13B MECOM CIT	1.41e-04	162	28	3	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	PPP4R1 EBF1 MYO9B	1.43e-04	163	28	3	6bed27d2f67a430a847da5eb47878d14b4949c45
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 UNC13C EBF1	1.48e-04	165	28	3	369d77a80d6401e85ea3121ab5a252f67d5f157e
ToppCell	Control\|World / group, cell type (main and fine annotations)	UNC13B MECOM USP54	1.56e-04	168	28	3	a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	UNC13B MECOM USP54	1.62e-04	170	28	3	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CIT RSPO1 WNT7A	1.62e-04	170	28	3	14aa86a4f526ed6986afcb28c49225522055550c
ToppCell	Pericytes-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	EBF2 RSPO1 UNC13A	1.65e-04	171	28	3	bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EBF2 EBF1 EBF3	1.68e-04	172	28	3	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	3'-Airway_Nasal-Endothelial-Blood_vessel_EC\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 EBF1 EBF3	1.71e-04	173	28	3	b7d8702409b86fbc8741a472b84d509ba261a852
ToppCell	3'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 EBF1 EBF3	1.71e-04	173	28	3	b83c9e274999c9325908616cee4a89d425c8c4ed
ToppCell	3'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 EBF1 EBF3	1.71e-04	173	28	3	0068c059ef118b5ef85c5b01ad8680ce11493aa5
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PCSK5 MECOM HSPG2	1.71e-04	173	28	3	3a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCell	3'-Airway_Nasal-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 EBF1 EBF3	1.71e-04	173	28	3	3c96e269ca7b7029f533268f68ca4466edd20edd
ToppCell	3'-Airway_Nasal-Endothelial\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	HSPG2 EBF1 EBF3	1.71e-04	173	28	3	383edcd3bb14d3934506260dbbac7167282546af
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZDHHC2 EBF2 CIT	1.73e-04	174	28	3	1c073177c1753e3b91ef8fd9e95230a1d13c82f3
ToppCell	facs-Lung-nan-3m-Lymphocytic-CD8+_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZDHHC2 EBF2 CIT	1.73e-04	174	28	3	5491ad5c144baf2ef9b1c58eb720c872d14feb15
ToppCell	3'_v3-blood-Mast-Mast_cell_granulo-myelo\|blood / Manually curated celltypes from each tissue	MECOM HSPG2 UNC13C	1.79e-04	176	28	3	d421b6b8e13894dbcf29548c0a6516c3dee8f9b1
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-AEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PCSK5 MECOM HSPG2	1.79e-04	176	28	3	77516048aefbe1f48e825052756df0c310c1c486
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	CIT RSPO1 WNT7A	1.79e-04	176	28	3	05ec715439f2eb1696f5d8855da0dd1dd70effd0
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MECOM USP54 CIT	1.85e-04	178	28	3	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PCSK5 MECOM HSPG2	1.89e-04	179	28	3	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	UNC13B MECOM USP54	1.89e-04	179	28	3	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	UNC13B MECOM USP54	1.89e-04	179	28	3	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	droplet-Lung-nan-21m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZDHHC2 ADAM11 CIT	1.89e-04	179	28	3	d78eacf47847a50888dd16c35bed9b7afc80010f
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	EBF2 MECOM EBF1	1.89e-04	179	28	3	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 MECOM EBF3	1.92e-04	180	28	3	67c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 EBF3 RSPO1	1.92e-04	180	28	3	c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EBF2 HSPG2 EBF1	1.92e-04	180	28	3	39ae8586efd91536e9ac6408d26de7e6d6237c41
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 EBF3 RSPO1	1.92e-04	180	28	3	32c6a3886428d82fb4355d987c6d2645f333447b
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MECOM HSPG2 EBF1	1.92e-04	180	28	3	97e0dcb7cfbba60a782824c5e23995058609fcd4
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 PCSK5 RSPO1	1.95e-04	181	28	3	269b39ac65790061d54eab47a8eeb024403f0348
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 PCSK5 RSPO1	1.95e-04	181	28	3	cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCell	5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PCSK5 MECOM HSPG2	1.95e-04	181	28	3	0ba91575fe8851788cebc4cf5a6d76680bf586c5
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 PCSK5 RSPO1	1.95e-04	181	28	3	c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZDHHC2 HSPG2 ADAM11	1.98e-04	182	28	3	a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	UNC13B PCSK5 MECOM	2.01e-04	183	28	3	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|tumor_Lung / Location, Cell class and cell subclass	EBF2 ZNF727 EBF1	2.01e-04	183	28	3	a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MECOM EBF1 EBF3	2.01e-04	183	28	3	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PCSK5 MECOM HSPG2	2.01e-04	183	28	3	351d575339038bd4a66f408da518c567444208e8
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	UNC13B PPP4R1 MECOM	2.04e-04	184	28	3	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MECOM HSPG2 EBF1	2.04e-04	184	28	3	9001d35cdde061d06f8545b3cee942d1299129db
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 EBF1 EBF3	2.04e-04	184	28	3	4d4d8f3f44c67d74c57e7af7b7c158f0157b2f49
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	UNC13B PPP4R1 MECOM	2.04e-04	184	28	3	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Endo-Endothelial-Endo_L2-5_CLDN5\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MECOM HSPG2 EBF1	2.04e-04	184	28	3	73eaac74a88bf5fd23d88035fac398ac43b268c5
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Endo\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MECOM HSPG2 EBF1	2.04e-04	184	28	3	65f651d4b93ed0b52f526d3f517d92b6c62aaec3
ToppCell	metastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	EBF2 HSPG2 EBF3	2.08e-04	185	28	3	506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	EBF2 EBF1 EBF3	2.08e-04	185	28	3	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	UNC13B MECOM USP54	2.08e-04	185	28	3	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ZDHHC2 RFFL ZZEF1	2.11e-04	186	28	3	74c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCell	5'-GW_trimst-2-LymphNode-Mesenchymal-Pericytes\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 EBF1 EBF3	2.11e-04	186	28	3	1e3ab663e4756975db6d802b2c6c054a94a79393
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 UNC13C EBF1	2.11e-04	186	28	3	0b2ce9b8a4382d583240647217ad5e2d3fa555c1
ToppCell	IPF-Epithelial-ATII\|World / Disease state, Lineage and Cell class	UNC13B MECOM USP54	2.11e-04	186	28	3	6a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	UNC13B MECOM HSPG2	2.11e-04	186	28	3	ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCell	COPD-Epithelial-Club\|World / Disease state, Lineage and Cell class	UNC13B MECOM USP54	2.11e-04	186	28	3	3006f4ab1eaf1eb34c10ca9f7c869603d2d25744
Disease	Anus, Imperforate	EBF2 PCSK5	8.06e-07	2	27	2	C0003466
Disease	Antihypertensive use measurement	EBF2 MECOM HSPG2 EBF1 MYO9B	3.86e-06	265	27	5	EFO_0009927
Disease	epilepsy (implicated_via_orthology)	UNC13B UNC13C CIT UNC13A	1.43e-05	163	27	4	DOID:1826 (implicated_via_orthology)
Disease	gastric ulcer	MECOM MYO9B	1.68e-04	21	27	2	EFO_0009454
Disease	Agents acting on the renin-angiotensin system use measurement	EBF2 MECOM EBF1 MYO9B	2.33e-04	335	27	4	EFO_0009931
Disease	clopidogrel metabolite measurement	RFFL RNF2	4.18e-04	33	27	2	EFO_0007966
Disease	waist-hip ratio	EBF2 PCSK5 MECOM EBF1 ZZEF1 MYO9B	7.10e-04	1226	27	6	EFO_0004343
Disease	alcohol use disorder (implicated_via_orthology)	UNC13B UNC13C UNC13A	7.40e-04	195	27	3	DOID:1574 (implicated_via_orthology)
Disease	vital capacity	PCSK5 MECOM HSPG2 EBF1 ZZEF1 WNT7A	7.41e-04	1236	27	6	EFO_0004312
Disease	cardiovascular disease	EBF2 MECOM EBF1 MYO9B	7.51e-04	457	27	4	EFO_0000319
Disease	body weight	UNC13B EBF2 PCSK5 MECOM EBF1 ZZEF1	8.22e-04	1261	27	6	EFO_0004338
Disease	testosterone measurement	EBF2 FHAD1 MECOM EBF1 SAXO1 MYO9B	8.71e-04	1275	27	6	EFO_0004908
Disease	mean arterial pressure	EBF2 MECOM EBF1 MYO9B	1.04e-03	499	27	4	EFO_0006340
Disease	PROSTATE CANCER, HEREDITARY, 1	MECOM MYO9B	1.38e-03	60	27	2	C4722327
Disease	migraine disorder, type 2 diabetes mellitus	EBF1 CIT	1.38e-03	60	27	2	MONDO_0005148, MONDO_0005277
Disease	Prostate cancer, familial	MECOM MYO9B	1.82e-03	69	27	2	C2931456
Disease	mitochondrial heteroplasmy measurement	UNC13C CIT	1.82e-03	69	27	2	EFO_0600008
Disease	mean arterial pressure, alcohol drinking	MECOM EBF1	3.63e-03	98	27	2	EFO_0004329, EFO_0006340
Disease	Dupuytren Contracture	EBF2 EBF1	4.39e-03	108	27	2	EFO_0004229
Disease	immature platelet fraction	PPP4R1 MYO9B	4.88e-03	114	27	2	EFO_0009187
Disease	diastolic blood pressure, alcohol drinking	MECOM EBF1	5.21e-03	118	27	2	EFO_0004329, EFO_0006336
Disease	immature platelet measurement	PPP4R1 MYO9B	5.30e-03	119	27	2	EFO_0803541

Protein segments in the cluster

Peptide	Gene	Start	Entry
GMRCTECGVKCHEKC	UNC13A	581	Q9UPW8
GNCCKKCTLTHDAMC	ADAM11	471	O75078
HDAMCSDGLCCRRCK	ADAM11	481	O75078
HEVMCSRCCEKKSCG	EBF2	156	Q9HAK2
KCLECQVMCHPKCST	CIT	1391	O14578
CLKCFCMGVSRHCTS	HSPG2	921	P98160
RHHCRLCGSIMCKKC	RBSN	176	Q9H1K0
RMHADCRTQIKCKDC	MECOM	396	Q03112
CPEMCQDCIHEKTCK	PCSK5	1326	Q92824
KECRDCHKSCLTCSS	PCSK5	1416	Q92824
LDSCQACMKISCCSH	FHAD1	566	B1AJZ9
ACMKISCCSHDLKKE	FHAD1	571	B1AJZ9
THEIMCSRCCDKKSC	EBF1	156	Q9UH73
THEIMCSRCCDKKSC	EBF3	156	Q9H4W6
TMTTKECLHRFCADC	RNF2	61	Q99496
MKASQCCCCLSHLLA	FAM174A	1	Q8TBP5
CCDCRMFHVRKVCAA	PPP4R1	221	Q8TF05
TPKMLDCCHSFCVEC	RNF183	26	Q96D59
MKTKCICELCSCGRH	SAXO1	1	Q8IYX7
CVLLECGHMVTCTKC	RFFL	326	Q8WZ73
MNKCIKCKIEHCEAC	RSPO1	91	Q2MKA7
CKECHKAFRCCSDLT	ZNF727	286	A8MUV8
MKCLECGVKCHEKCQ	UNC13C	1126	Q8NB66
MRCSECGVKCHEKCQ	UNC13B	506	O14795
CSICNRCVLKMDHHC	ZDHHC16	171	Q969W1
CCYVKCNTCSERTEM	WNT7A	331	O00755
RCLQCSDMDLCKTCF	ZZEF1	1796	O43149
CSICKRCIRKMDHHC	ZDHHC7	146	Q9NXF8
KPDRCHHCSVCDKCI	ZDHHC2	136	Q9UIJ5
THKCMGDSCIFCALK	USP54	66	Q70EL1
LCSVCKMTCHKKCVH	MYO9B	1661	Q13459