Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

IKZF3 ZNF573 ZSCAN31 PEG3 JDP2 ZBTB41 ZNF395 CREB1 ATF6B CREM RXRA RXRB HOXA13 ZSCAN32 SOHLH2 SMARCA4 CCAR1 ZNF808 MAFB ATF1 TAF1

3.86e-0614599521GO:0000977
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

IKZF3 ZNF573 ZSCAN31 JDP2 ZBTB41 ZNF395 CREB1 ATF6B CREM RXRA RXRB HOXA13 ZSCAN32 SOHLH2 SMARCA4 CCAR1 ZNF808 MAFB ATF1

5.23e-0612449519GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

IKZF3 ZNF573 ZSCAN31 JDP2 ZBTB41 ZNF395 CREB1 ATF6B CREM RXRA RXRB HOXA13 ZSCAN32 SOHLH2 SMARCA4 CCAR1 ZNF808 MAFB ATF1

7.12e-0612719519GO:0000987
GeneOntologyMolecularFunctionlysine-acetylated histone binding

BRD3 BRD4 SMARCA4 TAF1

1.20e-0530954GO:0070577
GeneOntologyMolecularFunctionacetylation-dependent protein binding

BRD3 BRD4 SMARCA4 TAF1

1.37e-0531954GO:0140033
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

ZNF438 IKZF3 ZNF573 ZSCAN31 PEG3 JDP2 ZBTB41 ZNF395 CREB1 ATF6B CREM RXRA RXRB HOXA13 ZSCAN32 SOHLH2 ZNF808 MAFB ATF1

3.12e-0514129519GO:0000981
GeneOntologyMolecularFunctionSNAP receptor activity

SEC22B STX1B STX18 STX7

3.48e-0539954GO:0005484
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

TRIM15 ANK3 ATG2B SEC22B BRD3 JMJD1C RXRB STX1B STX18 CARD9 BRD4 RNF20 SMARCA2 SMARCA4 CCAR1 STX7

1.09e-0411609516GO:0030674
GeneOntologyMolecularFunctionnuclear receptor binding

TACC2 JMJD1C RXRA RXRB SMARCA4 TAF1

2.71e-04187956GO:0016922
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

IKZF3 ZNF395 CREB1 ATF6B RXRB HOXA13 SOHLH2 ZNF808 MAFB ATF1

3.31e-045609510GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

IKZF3 ZNF395 CREB1 ATF6B RXRB HOXA13 SOHLH2 ZNF808 MAFB ATF1

3.60e-045669510GO:0001216
GeneOntologyMolecularFunctionretinoic acid-responsive element binding

RXRA RXRB

4.63e-047952GO:0044323
GeneOntologyMolecularFunctionp53 binding

BRD4 RNF20 SMARCA4 TAF1

4.99e-0477954GO:0002039
GeneOntologyMolecularFunctionnuclear thyroid hormone receptor binding

JMJD1C RXRA RXRB

5.61e-0434953GO:0046966
GeneOntologyMolecularFunctiontranscription coactivator activity

TRIM15 RXRB BRD4 RNF20 SMARCA2 SMARCA4 CCAR1

6.11e-04303957GO:0003713
GeneOntologyMolecularFunctionmolecular adaptor activity

TRIM15 ANK3 ATG2B SEC22B BRD3 JMJD1C RXRB STX1B STX18 CARD9 BRD4 RNF20 SMARCA2 SMARCA4 CCAR1 STX7

6.28e-0413569516GO:0060090
GeneOntologyMolecularFunctionchromatin binding

IKZF3 JDP2 BRD3 JMJD1C RXRA RXRB BRD4 RNF20 SMARCA2 SMARCA4 TAF1

7.66e-047399511GO:0003682
GeneOntologyMolecularFunctionmicrofilament motor activity

MYO9A MYO3A MYO3B

7.80e-0438953GO:0000146
GeneOntologyMolecularFunctionaspartic-type endopeptidase inhibitor activity

NLRP2 SORL1

7.89e-049952GO:0019828
GeneOntologyMolecularFunctioncAMP response element binding

JDP2 CREB1

1.43e-0312952GO:0035497
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXNA3 PLXNA1

1.43e-0312952GO:0017154
GeneOntologyMolecularFunctionhistone binding

BRD3 BRD4 RNF20 SMARCA2 SMARCA4 TAF1

1.67e-03265956GO:0042393
GeneOntologyMolecularFunctionmodification-dependent protein binding

ANK3 BRD3 BRD4 SMARCA4 TAF1

3.04e-03206955GO:0140030
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

TCEA1 IKZF3 PEG3 BRD3 ZNF395 CREB1 ATF6B CREM RXRA RXRB HOXA13 NAMPT SOHLH2 BRD4 RNF20 SMARCA2 SMARCA4 ZNF808 MAFB ATF1 TAF1

1.28e-0613909621GO:0045944
GeneOntologyBiologicalProcesscranial nerve formation

PLXNA3 MAFB PLXNA1

1.57e-0511963GO:0021603
GeneOntologyBiologicalProcessolfactory nerve formation

PLXNA3 PLXNA1

2.14e-052962GO:0021628
GeneOntologyBiologicalProcessolfactory nerve morphogenesis

PLXNA3 PLXNA1

6.41e-053962GO:0021627
GeneOntologyCellularComponentATF4-CREB1 transcription factor complex

CREB1 CREM ATF1

3.74e-074963GO:1990589
GeneOntologyCellularComponentRNA polymerase II transcription regulator complex

TCEA1 JDP2 CREB1 ATF6B CREM RXRA RXRB MAFB ATF1 TAF1

4.97e-072729610GO:0090575
GeneOntologyCellularComponentSNARE complex

SEC22B STX1B STX18 STX7

8.85e-0551964GO:0031201
GeneOntologyCellularComponentchromatin

JDP2 BRD3 CREB1 ATF6B JMJD1C CREM RXRA RXRB HOXA13 SOHLH2 BRD4 RNF20 SMARCA2 SMARCA4 MTBP MAFB ATF1 TAF1

1.22e-0414809618GO:0000785
GeneOntologyCellularComponenttranscription regulator complex

TCEA1 JDP2 CREB1 ATF6B CREM RXRA RXRB MAFB ATF1 TAF1

4.11e-045969610GO:0005667
GeneOntologyCellularComponentnuclear protein-containing complex

TCEA1 AFF3 JDP2 CREB1 ATF6B JMJD1C CREM RXRA RXRB BRD4 SMARCA2 SMARCA4 MAFB ATF1 TAF1 MX2

5.09e-0413779616GO:0140513
GeneOntologyCellularComponentbBAF complex

SMARCA2 SMARCA4

9.17e-0410962GO:0140092
GeneOntologyCellularComponentsemaphorin receptor complex

PLXNA3 PLXNA1

1.58e-0313962GO:0002116
GeneOntologyCellularComponentnuclear envelope lumen

CCAR1 SORL1

1.83e-0314962GO:0005641
GeneOntologyCellularComponentnpBAF complex

SMARCA2 SMARCA4

1.83e-0314962GO:0071564
GeneOntologyCellularComponentGBAF complex

SMARCA2 SMARCA4

1.83e-0314962GO:0140288
HumanPhenoAbnormal tarsal ossification

PTH1R HOXA13 EIF2AK3

1.36e-059293HP:0008369
HumanPhenoJoint dislocation

MYO9A CEP85L AFF3 JMJD1C TGFB2 BRD4 GPC4 SMARCA2 MAFB EIF2AK3

3.29e-053902910HP:0001373
HumanPhenoAbnormal hand bone ossification

PTH1R HOXA13 GPC4 MAFB EIF2AK3

3.90e-0570295HP:0010660
DomainKID

CREB1 CREM ATF1

1.32e-073963PS50953
DomainCoactivator_CBP_pKID

CREB1 CREM ATF1

1.32e-073963IPR003102
DomainpKID

CREB1 CREM ATF1

1.32e-073963PF02173
DomainBromodomain_CS

BRD3 BRD4 SMARCA2 SMARCA4 TAF1

1.95e-0726965IPR018359
DomainBRLZ

JDP2 CREB1 ATF6B CREM MAFB ATF1

2.65e-0752966SM00338
DomainBZIP

JDP2 CREB1 ATF6B CREM MAFB ATF1

2.97e-0753966PS50217
DomainBZIP_BASIC

JDP2 CREB1 ATF6B CREM MAFB ATF1

2.97e-0753966PS00036
DomainbZIP

JDP2 CREB1 ATF6B CREM MAFB ATF1

3.33e-0754966IPR004827
DomainLeuzip_CREB

CREB1 CREM ATF1

5.24e-074963IPR001630
DomainbZIP_1

JDP2 CREB1 ATF6B CREM ATF1

7.99e-0734965PF00170
DomainBROMODOMAIN_1

BRD3 BRD4 SMARCA2 SMARCA4 TAF1

1.24e-0637965PS00633
DomainTF_DNA-bd

CREB1 ATF6B CREM MAFB ATF1

1.24e-0637965IPR008917
DomainBromodomain

BRD3 BRD4 SMARCA2 SMARCA4 TAF1

1.42e-0638965PF00439
DomainBROMODOMAIN_2

BRD3 BRD4 SMARCA2 SMARCA4 TAF1

2.09e-0641965PS50014
DomainBROMO

BRD3 BRD4 SMARCA2 SMARCA4 TAF1

2.36e-0642965SM00297
DomainBromodomain

BRD3 BRD4 SMARCA2 SMARCA4 TAF1

2.36e-0642965IPR001487
Domain-

BRD3 BRD4 SMARCA2 SMARCA4 TAF1

2.36e-06429651.20.920.10
DomainSnAC

SMARCA2 SMARCA4

2.61e-052962SM01314
DomainGln-Leu-Gln_QLQ

SMARCA2 SMARCA4

2.61e-052962IPR014978
DomainSnAC

SMARCA2 SMARCA4

2.61e-052962IPR029295
DomainSnAC

SMARCA2 SMARCA4

2.61e-052962PF14619
DomainQLQ

SMARCA2 SMARCA4

2.61e-052962SM00951
DomainQLQ

SMARCA2 SMARCA4

2.61e-052962PS51666
DomainQLQ

SMARCA2 SMARCA4

2.61e-052962PF08880
DomainSyntaxin/epimorphin_CS

STX1B STX18 STX7

7.02e-0516963IPR006012
DomainSYNTAXIN

STX1B STX18 STX7

7.02e-0516963PS00914
DomainHSA

SMARCA2 SMARCA4

1.56e-044962SM00573
DomainBET

BRD3 BRD4

1.56e-044962PF17035
DomainNET_dom

BRD3 BRD4

1.56e-044962IPR027353
DomainHSA

SMARCA2 SMARCA4

1.56e-044962PS51204
DomainHSA_dom

SMARCA2 SMARCA4

1.56e-044962IPR014012
DomainHSA

SMARCA2 SMARCA4

1.56e-044962PF07529
DomainNET

BRD3 BRD4

1.56e-044962PS51525
DomainT_SNARE

STX1B STX18 STX7

3.14e-0426963PS50192
DomainBRK

SMARCA2 SMARCA4

3.87e-046962SM00592
DomainBRK_domain

SMARCA2 SMARCA4

3.87e-046962IPR006576
DomainBRK

SMARCA2 SMARCA4

3.87e-046962PF07533
DomainT_SNARE_dom

STX1B STX18 STX7

4.36e-0429963IPR000727
DomainPlexin_cytopl

PLXNA3 PLXNA1

9.19e-049962PF08337
DomainZU5

ANK3 UNC5D

9.19e-049962SM00218
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNA1

9.19e-049962IPR013548
DomainSynN

STX1B STX7

9.19e-049962SM00503
DomainPlexin

PLXNA3 PLXNA1

9.19e-049962IPR031148
DomainMyosin_head_motor_dom

MYO9A MYO3A MYO3B

9.74e-0438963IPR001609
DomainMYOSIN_MOTOR

MYO9A MYO3A MYO3B

9.74e-0438963PS51456
DomainMyosin_head

MYO9A MYO3A MYO3B

9.74e-0438963PF00063
DomainMYSc

MYO9A MYO3A MYO3B

9.74e-0438963SM00242
DomainRetinoid-X_rcpt/HNF4

RXRA RXRB

1.15e-0310962IPR000003
DomainZU5

ANK3 UNC5D

1.15e-0310962PS51145
Domain-

ANK3 NLRP2 CARD9 UNC5D

1.35e-03939641.10.533.10
DomainSyntaxin

STX1B STX7

1.40e-0311962PF00804
Domaint-SNARE

STX1B STX18 STX7

1.40e-0343963IPR010989
DomainZU5

ANK3 UNC5D

1.67e-0312962PF00791
DomainSyntaxin_N

STX1B STX7

1.67e-0312962IPR006011
DomainZU5_dom

ANK3 UNC5D

1.67e-0312962IPR000906
DomainDEATH-like_dom

ANK3 NLRP2 CARD9 UNC5D

1.70e-0399964IPR011029
DomainSCAN

ZSCAN31 PEG3 ZSCAN32

3.00e-0356963SM00431
DomainSCAN_BOX

ZSCAN31 PEG3 ZSCAN32

3.31e-0358963PS50804
DomainSCAN

ZSCAN31 PEG3 ZSCAN32

3.31e-0358963PF02023
DomainSCAN_dom

ZSCAN31 PEG3 ZSCAN32

3.31e-0358963IPR003309
DomainRetrov_capsid_C

ZSCAN31 PEG3 ZSCAN32

3.47e-0359963IPR008916
PathwayWP_VITAMIN_D_METABOLISM

GC RXRA RXRB

1.10e-0510653M39352
PathwayKEGG_SNARE_INTERACTIONS_IN_VESICULAR_TRANSPORT

SEC22B STX1B STX18 STX7

2.70e-0538654M17857
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PLXNA3 PAK3 PLXNA1

3.28e-0514653MM15029
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PLXNA3 PAK3 PLXNA1

5.02e-0516653M16498
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_LIMIT_CHOLESTEROL_UPTAKE

RXRA RXRB

2.07e-045652M29791
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_TRIGLYCERIDE_LIPOLYSIS_IN_ADIPOSE

RXRA RXRB

2.07e-045652M29792
PathwayKEGG_MEDICUS_VARIANT_PAX8_PPARG_FUSION_TO_PPARG_MEDIATED_TRANSCRIPTION

RXRA RXRB

2.07e-045652M49023
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_GLUCONEOGENESIS

RXRA RXRB

2.07e-045652M29812
PathwayREACTOME_CIRCADIAN_CLOCK

CREB1 CREM RXRA NAMPT

3.00e-0470654M938
PathwayWP_VITAMIN_A1_AND_A5X_PATHWAYS

RXRA RXRB

3.10e-046652M48097
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS

RXRA RXRB

3.10e-046652MM15663
PathwayWP_KLEEFSTRA_SYNDROME

RXRA SMARCA2 SMARCA4

3.14e-0429653M48076
PathwayREACTOME_CREB_PHOSPHORYLATION

CREB1 ATF1

4.33e-047652M27096
PathwayREACTOME_CREB_PHOSPHORYLATION

CREB1 ATF1

4.33e-047652MM14784
PathwayREACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION

PLXNA3 PLXNA1

7.38e-049652MM15030
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_LINKED_TO_LIPOGENESIS

RXRA RXRB

7.38e-049652M29789
PathwayKEGG_MEDICUS_REFERENCE_THYROID_HORMONE_SIGNALING_PATHWAY

RXRA RXRB

7.38e-049652M47629
PathwayREACTOME_NR1H2_NR1H3_REGULATE_GENE_EXPRESSION_TO_CONTROL_BILE_ACID_HOMEOSTASIS

RXRA RXRB

7.38e-049652M29809
PathwayREACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_PIGMENTATION

CREB1 SMARCA2 SMARCA4

9.45e-0442653M48237
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ZNF438 TCEA1 PLXNA3 PEG3 ZBTB41 BRD3 ATF6B CREM RXRA RXRB SOHLH2 BRD4 SMARCA2 CCAR1 ATF1 PLXNA1

8.56e-10808971620412781
Pubmed

Secalonic acid D alters the expression and phosphorylation of the transcription factors and their binding to cAMP response element in developing murine secondary palate.

CREB1 CREM ATF1

8.40e-08497311354513
Pubmed

EWSR1 Fusions With CREB Family Transcription Factors Define a Novel Myxoid Mesenchymal Tumor With Predilection for Intracranial Location.

CREB1 CREM ATF1

8.40e-08497328009602
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

TCEA1 PLXNA3 PEG3 BRD3 TACC2 CREM RXRA RXRB HOXA13 BRD4 SMARCA2 SMARCA4 PLXNA1

9.13e-08709971322988430
Pubmed

Disruption of CREB function in brain leads to neurodegeneration.

CREB1 CREM ATF1

2.09e-07597311967539
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TCEA1 RBBP6 BRD3 CCNY MYO3A NOL4L BRD4 RNF20 SMARCA2 SMARCA4 CCAR1 PLEC UNC5D

2.49e-07774971315302935
Pubmed

Activating transcription factor 1 and CREB are important for cell survival during early mouse development.

CREB1 CREM ATF1

4.18e-07697311865068
Pubmed

Activation of ATP-binding cassette transporter A1 transcription by chromatin remodeling complex.

RXRA SMARCA2 SMARCA4

4.18e-07697315774904
Pubmed

Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.

ADAMTSL1 RBBP6 JDP2 TACC2 LGSN ZNF804A CCDC27 MYO3A CARD9 MYO3B MAFB ADGRL2 PCDH18

4.39e-07814971323251661
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

CREB1 JMJD1C PRR12 BRD4 RNF20 SMARCA2 SMARCA4 TAF1

8.95e-0726897833640491
Pubmed

Specific ablation of the transcription factor CREB in sympathetic neurons surprisingly protects against developmentally regulated apoptosis.

CREB1 CREM ATF1

1.17e-06897317376811
Pubmed

Protein kinase A signalling via CREB controls myogenesis induced by Wnt proteins.

CREB1 CREM ATF1

1.75e-06997315568017
Pubmed

Apoptosis, axonal growth defects, and degeneration of peripheral neurons in mice lacking CREB.

CREB1 CREM ATF1

1.75e-06997311988169
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

BRD3 BRD4 SMARCA2 SMARCA4 TAF1

2.25e-067597525593309
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

TCEA1 RBBP6 CREB1 JMJD1C CREM HOXA13 SLC35F3 BRD4 SMARCA4 CCAR1 ZNF808 ATF1 TAF1

2.55e-06954971336373674
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ATXN7L2 RBBP6 JDP2 SEC22B BRD3 ZNF395 CREB1 JMJD1C CREM PRR12 BRD4 RNF20 SMARCA4 CCAR1 ATF1

2.96e-061294971530804502
Pubmed

Ikaros DNA-binding proteins direct formation of chromatin remodeling complexes in lymphocytes.

IKZF3 SMARCA2 SMARCA4

3.41e-061197310204490
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

TCEA1 RBBP6 BRD3 RXRA NAMPT BRD4 RNF20 SMARCA2 SMARCA4 CCAR1 ATF1 TAF1 PLEC

4.94e-061014971332416067
Pubmed

The transcription factor Mesp1 interacts with cAMP-responsive element binding protein 1 (Creb1) and coactivates Ets variant 2 (Etv2) gene expression.

CREB1 CREM ATF1

5.89e-061397325694434
Pubmed

Vitamin D-related genes, serum vitamin D concentrations and prostate cancer risk.

GC RXRA RXRB

5.89e-061397319255064
Pubmed

The expanding family of CREB/CREM transcription factors that are involved with spermatogenesis.

CREB1 CREM

7.70e-06297211988318
Pubmed

RXR alpha mutant mice establish a genetic basis for vitamin A signaling in heart morphogenesis.

RXRA RXRB

7.70e-0629727926783
Pubmed

Mouse class III myosins: kinase activity and phosphorylation sites.

MYO3A MYO3B

7.70e-06297221895655
Pubmed

The hbrm and BRG-1 proteins, components of the human SNF/SWI complex, are phosphorylated and excluded from the condensed chromosomes during mitosis.

SMARCA2 SMARCA4

7.70e-0629728670841
Pubmed

Neurogenic transdifferentiation of human adipose-derived stem cells? A critical protocol reevaluation with special emphasis on cell proliferation and cell cycle alterations.

CREB1 ATF1

7.70e-06297220945072
Pubmed

Lung cancer with loss of BRG1/BRM, shows epithelial mesenchymal transition phenotype and distinct histologic and genetic features.

SMARCA2 SMARCA4

7.70e-06297223163725
Pubmed

CREB function is required for normal thymic cellularity and post-irradiation recovery.

CREB1 ATF1

7.70e-06297215214044
Pubmed

Combined gene dosage requirement for SWI/SNF catalytic subunits during early mammalian development.

SMARCA2 SMARCA4

7.70e-06297223076393
Pubmed

Increased hippocampal neurogenesis and accelerated response to antidepressants in mice with specific deletion of CREB in the hippocampus: role of cAMP response-element modulator τ.

CREB1 CREM

7.70e-06297223966689
Pubmed

Reversible inhibition of CREB/ATF transcription factors in region CA1 of the dorsal hippocampus disrupts hippocampus-dependent spatial memory.

CREB1 ATF1

7.70e-06297211988175
Pubmed

Differential preimplantation regulation of two mouse homologues of the yeast SWI2 protein.

SMARCA2 SMARCA4

7.70e-0629729603422
Pubmed

The SWI/SNF chromatin remodeling protein Brg1 is required for vertebrate neurogenesis and mediates transactivation of Ngn and NeuroD.

SMARCA2 SMARCA4

7.70e-06297215576411
Pubmed

The role of cAMP response element-binding protein in estrogen negative feedback control of gonadotropin-releasing hormone neurons.

CREB1 CREM

7.70e-06297222895714
Pubmed

SWI/SNF gene variants and glioma risk and outcome.

SMARCA2 SMARCA4

7.70e-06297223276717
Pubmed

Differential Expression of SWI/SNF Chromatin Remodeler Subunits Brahma and Brahma-Related Gene During Drug-Induced Liver Injury and Regeneration in Mouse Model.

SMARCA2 SMARCA4

7.70e-06297227097303
Pubmed

Chromatin remodeling factors and BRM/BRG1 expression as prognostic indicators in non-small cell lung cancer.

SMARCA2 SMARCA4

7.70e-06297215240517
Pubmed

Concomitant loss of SMARCA2 and SMARCA4 expression in small cell carcinoma of the ovary, hypercalcemic type.

SMARCA2 SMARCA4

7.70e-06297226564006
Pubmed

SMARCA4/SMARCA2-deficient Carcinoma of the Esophagus and Gastroesophageal Junction.

SMARCA2 SMARCA4

7.70e-06297233027072
Pubmed

SMARCA4 and SMARCA2 deficiency in non-small cell lung cancer: immunohistochemical survey of 316 consecutive specimens.

SMARCA2 SMARCA4

7.70e-06297228038711
Pubmed

cAMP response element-binding protein regulates differentiation and survival of newborn neurons in the olfactory bulb.

CREB1 CREM

7.70e-06297216267218
Pubmed

A synthetic lethality-based strategy to treat cancers harboring a genetic deficiency in the chromatin remodeling factor BRG1.

SMARCA2 SMARCA4

7.70e-06297223872584
Pubmed

Proinflammatory stimuli engage Brahma related gene 1 and Brahma in endothelial injury.

SMARCA2 SMARCA4

7.70e-06297223963727
Pubmed

Retinoid-X-receptors (α/β) in melanocytes modulate innate immune responses and differentially regulate cell survival following UV irradiation.

RXRA RXRB

7.70e-06297224810760
Pubmed

Cyclic adenosine 5'-monophosphate response element binding protein plays a central role in mediating proliferation and differentiation downstream of the pre-TCR complex in developing thymocytes.

CREB1 CREM

7.70e-06297215265911
Pubmed

SW13 cells can transition between two distinct subtypes by switching expression of BRG1 and Brm genes at the post-transcriptional level.

SMARCA2 SMARCA4

7.70e-06297212493776
Pubmed

Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4.

SMARCA2 SMARCA4

7.70e-06297231375262
Pubmed

Alterations of the SWI/SNF chromatin remodelling subunit-BRG1 and BRM in hepatocellular carcinoma.

SMARCA2 SMARCA4

7.70e-06297223088494
Pubmed

Aberrant expression of SWI/SNF catalytic subunits BRG1/BRM is associated with tumor development and increased invasiveness in prostate cancers.

SMARCA2 SMARCA4

7.70e-06297217075831
Pubmed

Limited degradation of retinoid X receptor by calpain.

RXRA RXRB

7.70e-0629728780715
Pubmed

SWI/SNF chromatin remodeling enzyme ATPases promote cell proliferation in normal mammary epithelial cells.

SMARCA2 SMARCA4

7.70e-06297220333683
Pubmed

Cyclic AMP response element-binding protein is required for normal maternal nurturing behavior.

CREB1 CREM

7.70e-06297215893884
Pubmed

SWI/SNF Complex-deficient Undifferentiated Carcinoma of the Gastrointestinal Tract: Clinicopathologic Study of 30 Cases With an Emphasis on Variable Morphology, Immune Features, and the Prognostic Significance of Different SMARCA4 and SMARCA2 Subunit Deficiencies.

SMARCA2 SMARCA4

7.70e-06297234812766
Pubmed

Nuclear hormone retinoid X receptor (RXR) negatively regulates the glucose-stimulated insulin secretion of pancreatic ß-cells.

RXRA RXRB

7.70e-06297220798333
Pubmed

Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity.

RXRA RXRB

7.70e-06297222316320
Pubmed

Loss of SWI/SNF Chromatin Remodeling Alters NRF2 Signaling in Non-Small Cell Lung Carcinoma.

SMARCA2 SMARCA4

7.70e-06297232855269
Pubmed

Abnormal long-lasting synaptic plasticity and cognition in mice lacking the mental retardation gene Pak3.

CREB1 PAK3

7.70e-06297216014725
Pubmed

Targeting of BRM Sensitizes BRG1-Mutant Lung Cancer Cell Lines to Radiotherapy.

SMARCA2 SMARCA4

7.70e-06297230478150
Pubmed

Downregulation of SWI/SNF chromatin remodeling factor subunits modulates cisplatin cytotoxicity.

SMARCA2 SMARCA4

7.70e-06297222721696
Pubmed

Targeting of the CREB gene leads to up-regulation of a novel CREB mRNA isoform.

CREB1 CREM

7.70e-0629728605879
Pubmed

Genetic variant of RXR involved in the vitamin D metabolic pathway was linked to HCV infection outcomes among a high-risk Chinese population.

RXRA RXRB

7.70e-06297233246082
Pubmed

BRD3 and BRD4 BET Bromodomain Proteins Differentially Regulate Skeletal Myogenesis.

BRD3 BRD4

7.70e-06297228733670
Pubmed

Endogenous retinoid X receptor ligands in mouse hematopoietic cells.

RXRA RXRB

7.70e-06297229089448
Pubmed

Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter.

SMARCA2 SMARCA4

7.70e-06297218508913
Pubmed

Epistatic interaction of CREB1 and KCNJ6 on rumination and negative emotionality.

CREB1 KCNJ6

7.70e-06297220943350
Pubmed

Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.

SMARCA2 SMARCA4

7.70e-06297211719516
Pubmed

The SWI/SNF ATPases Are Required for Triple Negative Breast Cancer Cell Proliferation.

SMARCA2 SMARCA4

7.70e-06297225808524
Pubmed

Antagonistic roles for BRM and BRG1 SWI/SNF complexes in differentiation.

SMARCA2 SMARCA4

7.70e-06297219144648
Pubmed

DNA binding drives the association of BRG1/hBRM bromodomains with nucleosomes.

SMARCA2 SMARCA4

7.70e-06297228706277
Pubmed

Depletion of cAMP-response element-binding protein/ATF1 inhibits adipogenic conversion of 3T3-L1 cells ectopically expressing CCAAT/enhancer-binding protein (C/EBP) alpha, C/EBP beta, or PPAR gamma 2.

CREB1 ATF1

7.70e-06297217071615
Pubmed

Three retinoid X receptor gene polymorphisms in plaque psoriasis and psoriasis guttata.

RXRA RXRB

7.70e-06297217341859
Pubmed

Impact of the Motor and Tail Domains of Class III Myosins on Regulating the Formation and Elongation of Actin Protrusions.

MYO3A MYO3B

7.70e-06297227582493
Pubmed

[Expression of BRG1 and BRM proteins in prostatic cancer].

SMARCA2 SMARCA4

7.70e-06297221092585
Pubmed

CREB is activated by ER stress and modulates the unfolded protein response by regulating the expression of IRE1α and PERK.

CREB1 EIF2AK3

7.70e-06297226642955
Pubmed

High expression of SMARCA4 or SMARCA2 is frequently associated with an opposite prognosis in cancer.

SMARCA2 SMARCA4

7.70e-06297229391527
Pubmed

Association of increased genotypes risk for bipolar disorder with brain white matter integrity investigated with tract-based spatial statistics: Special Section on "Translational and Neuroscience Studies in Affective Disorders". Section Editor, Maria Nobile MD, PhD. This Section of JAD focuses on the relevance of translational and neuroscience studies in providing a better understanding of the neural basis of affective disorders. The main aim is to briefly summarise relevant research findings in clinical neuroscience with particular regards to specific innovative topics in mood and anxiety disorders.

ANK3 ZNF804A

7.70e-06297228648753
Pubmed

ANK3 rs10994336 and ZNF804A rs7597593 polymorphisms: genetic interaction for emotional and behavioral symptoms of alcohol withdrawal syndrome.

ANK3 ZNF804A

7.70e-06297238702695
Pubmed

Expression of SMARCA2 and SMARCA4 in gastric adenocarcinoma and construction of a nomogram prognostic model.

SMARCA2 SMARCA4

7.70e-06297237634210
Pubmed

SWI/SNF Complex-deficient Undifferentiated/Rhabdoid Carcinomas of the Gastrointestinal Tract: A Series of 13 Cases Highlighting Mutually Exclusive Loss of SMARCA4 and SMARCA2 and Frequent Co-inactivation of SMARCB1 and SMARCA2.

SMARCA2 SMARCA4

7.70e-06297226551623
Pubmed

Impaired expression of the inducible cAMP early repressor accounts for sustained adipose CREB activity in obesity.

CREB1 CREM

7.70e-06297221998402
Pubmed

Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin.

RXRA RXRB

7.70e-06297216199515
Pubmed

Cell-specific occupancy of an extended repertoire of CREM and CREB binding loci in male germ cells.

CREB1 CREM

7.70e-06297220920259
Pubmed

SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity.

SMARCA2 SMARCA4

7.70e-06297219458193
Pubmed

Transgenic mice lacking CREB and CREM in noradrenergic and serotonergic neurons respond differently to common antidepressants on tail suspension test.

CREB1 CREM

7.70e-06297229044198
Pubmed

Recruitment of Brd3 and Brd4 to acetylated chromatin is essential for proinflammatory cytokine-induced matrix-degrading enzyme expression.

BRD3 BRD4

7.70e-06297230786900
Pubmed

Two human homologues of Saccharomyces cerevisiae SWI2/SNF2 and Drosophila brahma are transcriptional coactivators cooperating with the estrogen receptor and the retinoic acid receptor.

SMARCA2 SMARCA4

7.70e-0629728208605
Pubmed

The Bromodomains of the mammalian SWI/SNF (mSWI/SNF) ATPases Brahma (BRM) and Brahma Related Gene 1 (BRG1) promote chromatin interaction and are critical for skeletal muscle differentiation.

SMARCA2 SMARCA4

7.70e-06297234289068
Pubmed

BRD3/4 inhibition and FLT3-ligand deprivation target pathways that are essential for the survival of human MLL-AF9+ leukemic cells.

BRD3 BRD4

7.70e-06297229240787
Pubmed

SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria.

SMARCA2 SMARCA4

7.70e-06297234518526
Pubmed

SMARCA family of genes.

SMARCA2 SMARCA4

7.70e-06297232312722
Pubmed

Dual loss of the SWI/SNF complex ATPases SMARCA4/BRG1 and SMARCA2/BRM is highly sensitive and specific for small cell carcinoma of the ovary, hypercalcaemic type.

SMARCA2 SMARCA4

7.70e-06297226356327
Pubmed

An isoform of transcription factor CREM expressed during spermatogenesis lacks the phosphorylation domain and represses cAMP-induced transcription.

CREB1 CREM

7.70e-0629727809053
Pubmed

A transcriptionally silent RXRalpha supports early embryonic morphogenesis and heart development.

RXRA RXRB

7.70e-06297219255444
Pubmed

Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis.

SMARCA2 SMARCA4

7.70e-06297212566296
Pubmed

A Brg1 null mutation in the mouse reveals functional differences among mammalian SWI/SNF complexes.

SMARCA2 SMARCA4

7.70e-06297211163203
Pubmed

Identification of human myometrial target genes of the cAMP pathway: the role of cAMP-response element binding (CREB) and modulator (CREMalpha and CREMtau2alpha) proteins.

CREB1 CREM

7.70e-06297215691874
Pubmed

Human CREM gene: evolutionary conservation, chromosomal localization, and inducibility of the transcript.

CREB1 CREM

7.70e-0629727916662
Pubmed

Transcriptional specificity of human SWI/SNF BRG1 and BRM chromatin remodeling complexes.

SMARCA2 SMARCA4

7.70e-06297212620226
Pubmed

Cyclic AMP response element binding protein CREB and modulator protein CREM are products of distinct genes.

CREB1 CREM

7.70e-0629721461747
Pubmed

SMARCA2-deficiency confers sensitivity to targeted inhibition of SMARCA4 in esophageal squamous cell carcinoma cell lines.

SMARCA2 SMARCA4

7.70e-06297231406271
Pubmed

BRG1 and BRM SWI/SNF ATPases redundantly maintain cardiomyocyte homeostasis by regulating cardiomyocyte mitophagy and mitochondrial dynamics in vivo.

SMARCA2 SMARCA4

7.70e-06297227039070
InteractionNR4A2 interactions

CREB1 RXRA RXRB SMARCA2 SMARCA4

1.64e-0727965int:NR4A2
InteractionTAF11 interactions

TCEA1 BRD3 RXRA RXRB TAF1

4.36e-0651965int:TAF11
Cytoband4p15.32

FAM200B FGFBP1

5.20e-04169724p15.32
Cytoband10p11.21

CREM CCNY

7.38e-041997210p11.21
CytobandEnsembl 112 genes in cytogenetic band chr10q21

ANK3 JMJD1C CCAR1

2.05e-03118973chr10q21
Cytoband10q21.3

JMJD1C CCAR1

2.37e-033497210q21.3
CytobandEnsembl 112 genes in cytogenetic band chr10p11

ZNF438 CREM CCNY

2.52e-03127973chr10p11
GeneFamilyBasic leucine zipper proteins

JDP2 CREB1 ATF6B CREM MAFB ATF1

2.11e-0849656506
GeneFamilyMyosins, class III|Deafness associated genes

MYO3A MYO3B

1.27e-0526521099
GeneFamilySyntaxins

STX1B STX18 STX7

2.40e-0516653818
GeneFamilyPlexins

PLXNA3 PLXNA1

4.51e-049652683
GeneFamilyNon-clustered protocadherins

PCDH17 PCDH18

8.21e-041265221
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF438 IKZF3 ZNF573 ZSCAN31 PEG3 ZBTB41 ZNF395 ZSCAN32 ZNF808

1.02e-0371865928
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_500

ADAMTSL1 RBBP6 PEG3 AFF3 TGFB2 ADGRL2 PCDH18

2.18e-05188957gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k3
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000

ADAMTSL1 RBBP6 PEG3 AFF3 TGFB2 SMARCA2 ADGRL2 PCDH18

4.55e-05288958gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4

IL13RA1 ADAMTSL1 BEND5 PEG3 AFF3 SLC22A15 JDP2 PTH1R STX1B TGFB2 SMARCA2 PAK3 PRR14L UPP2 PCDH18 SORL1

4.67e-0511489516facebase_RNAseq_e14.5_palate_poster_oral_Tgfbr2_WT_2500_K4
CoexpressionAtlasdev gonad_e11.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_100

PEG3 AFF3 PCDH18

7.98e-0519953gudmap_dev gonad_e11.5_F_SupCellPrec_Sry_k2_100
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

IKZF3 JMJD1C CREM NAMPT MX2 SORL1

2.85e-0618197671e55acd1d8e4307e56534c74a50e7be4d1dda0d
ToppCellPBMC-Severe-cDC_5|Severe / Compartment, Disease Groups and Clusters

JDP2 JMJD1C CREM CCNY NAMPT RASGEF1B

4.24e-06194976b903e23eb75733ca516770727097fe74a9f8c1d1
ToppCellControl-Classical_Monocyte-cMono_2|Control / Disease condition and Cell class

IL13RA1 JMJD1C RXRA CCNY NAMPT SORL1

4.37e-061959760fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JMJD1C CREM NAMPT RASGEF1B MAFB EIF2AK3

4.50e-0619697601cea0bb0b938d0986fd2ddae06597b8af1768ee
ToppCellPBMC-Mild-cDC_0|Mild / Compartment, Disease Groups and Clusters

SLC22A15 JDP2 ZNF395 RXRA MAFB SORL1

4.77e-06198976fb873b7636bb1c7b119dd5b23d7a20f518e6c6da
ToppCellsevere-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

JMJD1C RXRA NAMPT RASGEF1B MAFB SORL1

4.77e-06198976d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCellMild/Remission-B_intermediate-0|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

IKZF3 ANK3 AFF3 SLC22A15 ZNF395 ZNF804A

4.91e-06199976592111591f0f6816fc56620cb555eb48dabf0758
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

ANK3 AFF3 SLC35F3 PAK3 ADGRL2 UNC5D

5.05e-0620097648d801219bc771d6c7e151dc88ca4c179988de85
ToppCellInfluenza|World / Disease, condition lineage and cell class

JDP2 RXRA CCNY NAMPT MAFB PLEC

5.05e-06200976df996c35907a1c9194b9e2ca30e81f520ca067f0
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

IL13RA1 PCDH17 GPC4 NXPH2 MX2

1.39e-051409752c44e8cc5190226049be7ebc465d685393e701c4
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC146 ACSM4 TTLL6 ABCC12 ODAD3

2.00e-05151975e335dad89e0a44cdd302b9653154ba5d1ee5fe1a
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CCDC146 ACSM4 TTLL6 ABCC12 ODAD3

2.00e-05151975633ed52dd3b4cf1e87432cf0a1ca187d7b204e83
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ATXN7L2 WDR93 CARD9 MX2 SORL1

3.15e-05166975de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HTR2B JDP2 CREM RASGEF1B MAFB

3.74e-0517297553dbfe1ac658fd94370cf8e745048cb67fda1daf
ToppCellmild_COVID-19_(asymptomatic)-B_memory|World / disease group, cell group and cell class (v2)

ANK3 BEND5 AFF3 KCNJ6 GRAMD1C

4.28e-05177975057871e211c6508b2a679d391f3cf0ac7ccfc628
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JDP2 RXRA RASGEF1B MAFB MX2

4.64e-051809756f8fa9fa91cd25b92584972bb34d90c483222f52
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 PTH1R TGFB2 CARD9 GPC4

5.02e-051839750e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTSL1 PTH1R TGFB2 CARD9 GPC4

5.02e-05183975cbc3b00faa7e4e0dbbbc8ee105467c65241c7470
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JMJD1C CREM NAMPT RASGEF1B MAFB

5.15e-05184975b45b1fdba13c8ed2a04a4fb3b62d8ad92785c768
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTH1R TGFB2 CARD9 GPC4 PCDH18

5.28e-05185975a6cd90f8f30c7bdf66958cf403e73c193aa32f5e
ToppCellfacs-Lung-24m-Mesenchymal-myofibroblast-pericyte_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTH1R TGFB2 CARD9 GPC4 PCDH18

5.28e-051859755053f932e2adfcf4d6faaecff2999ac53d8d7aa5
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANK3 PEG3 TGFB2 GPC4 PAK3

5.28e-051859753b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

JMJD1C RXRA MAFB PLEC UNC5D

5.42e-0518697523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CEP85L AFF3 PCDH17 SMARCA2 ADGRL2

5.56e-05187975ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 GC GPC4 PAK3 MAFB

5.70e-05188975e99e3765b48392c987cf0c5ccbded0655637d7b7
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

IL13RA1 AFF3 RASGEF1B GRAMD1C EIF2AK3

5.99e-051909751e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellfacs-Thymus-Epithelium-24m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 GC WDR93 PAK3 MAFB

6.15e-05191975eec14997d2bfc7e6b5a601afc43a147f6b96d668
ToppCellfacs-Thymus-Epithelium-24m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 GC WDR93 PAK3 MAFB

6.15e-051919751730ec5dc1cfd2f0cba7e21555641c7bce97e09d
ToppCellfacs-Pancreas-Endocrine-3m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 GC GPC4 PAK3 MAFB

6.15e-05191975b3de0393d6510543533cd851e47a0f95739a0e4e
ToppCellfacs-Thymus-Epithelium-24m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PEG3 GC WDR93 PAK3 MAFB

6.15e-051919754b77abc68bd72c64e7062f9527fe9d9605289ceb
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

IL13RA1 JDP2 RXRA NAMPT MAFB

6.30e-05192975f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IL13RA1 JDP2 RXRA NAMPT MAFB

6.30e-051929750219093e7921a0db78053aee13ec480b520f5662
ToppCelldroplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADAMTSL1 PEG3 WNT9A GRAMD1C PCDH18

6.46e-0519397564edc1d6fb0fe117767d494cf4a5723bf8be2804
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CEP85L AFF3 PCDH17 SMARCA2 ADGRL2

6.46e-05193975aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

JDP2 RXRA NAMPT MAFB PLEC

6.46e-051939751db487e5f81849740d57cc3e2b5739e8f7581efb
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CEP85L AFF3 PCDH17 SMARCA2 ADGRL2

6.46e-05193975c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCell368C-Lymphocytic-B_cell-|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TCEA1 IL13RA1 AFF3 RASGEF1B STX7

6.61e-051949759a72b6a3217b100617f468aaad48566a04334f3c
ToppCell368C-Lymphocytic-B_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TCEA1 IL13RA1 AFF3 RASGEF1B STX7

6.61e-05194975f8c46c5855a684ed5cb5289da4c29cf3e6052b97
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

AFF3 JMJD1C RASGEF1B STX7 EIF2AK3

6.61e-05194975ff661419b697aef51a53fdeac8d37d870d65f491
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

JDP2 CREM NAMPT RASGEF1B MAFB

6.61e-05194975449ce4167d64c170d914e0250f739eabedcf915d
ToppCellfacs-Lung-18m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HTR2B AFF3 SMARCA2 ADGRL2 PLXNA1

6.78e-051959757e0ef92059ff34e368d2324815f49b50e3ca7332
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

AFF3 SLC35F3 PAK3 ADGRL2 UNC5D

6.94e-05196975676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellcontrol-Myeloid-Non-resident_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

JMJD1C RXRA NAMPT MAFB SORL1

7.11e-05197975df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCellP03-Mesenchymal-myocytic_cell|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

IL13RA1 WNT9A PTH1R TGFB2 GPC4

7.11e-05197975079db904a08743b3c555cb7b3f5fb5c978dde25a
ToppCellCOVID-19_Severe-Non-classical_Monocyte|World / disease group, cell group and cell class

JDP2 RXRA NAMPT RASGEF1B MAFB

7.11e-0519797560fee75b12451206bb2c07b61651a73c59ec6ade
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

JMJD1C CREM NAMPT MAFB MX2

7.11e-051979750c059476a8cdc6ac71a01d9c414295177f45f8de
ToppCellmild_COVID-19-Classical_Monocyte|World / disease group, cell group and cell class (v2)

IL13RA1 RXRA NAMPT RASGEF1B MAFB

7.11e-051979755d826f4d7b7a46847c67e6bef38eb860bc808a6c
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

JDP2 RXRA PCDH17 NAMPT MAFB

7.11e-051979757870c0651caefb0ed13d9f9dab43b5f24d6a9efc
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JDP2 RXRA NAMPT RASGEF1B MAFB

7.28e-0519897506201b34d3e38f22c93b759511f7b376504bac06
ToppCellbackground-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

ADAMTSL1 ANK3 GC PTH1R RASGEF1B

7.28e-0519897579f32f965aed6a10c5cb803173e3db7b32e07a91
ToppCellmild_COVID-19-Classical_Monocyte|mild_COVID-19 / disease group, cell group and cell class (v2)

IL13RA1 JDP2 RXRA NAMPT MAFB

7.28e-051989755b31b6e008e05d6528656114fbe0ccae8ffe13b1
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

JDP2 RXRA NAMPT RASGEF1B MAFB

7.28e-051989751ca91559fef231896e16180f5e050155c38f7cfa
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ANK3 PEG3 AFF3 PAK3 ADGRL2

7.28e-051989750ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RBBP6 RXRA NAMPT RASGEF1B MAFB

7.46e-051999755b6feacb0ca92c3fc6b327be978320426dcf6f68
ToppCellcontrol-CD163+_Monocytes_(Sample_ID1_d7)|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IL13RA1 RXRA NAMPT MAFB MX2

7.46e-05199975933201d32eda12a89660bdbae9114a95cc428a38
ToppCellControl_saline|World / Treatment groups by lineage, cell group, cell type

ZSCAN31 PCDH17 TGFB2 PLEC ADGRL2

7.46e-0519997511c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell3'_v3-blood-Myeloid_Monocytic|blood / Manually curated celltypes from each tissue

IL13RA1 JDP2 RXRA NAMPT MAFB

7.46e-05199975bf3a5085a5ae50f2ef745dce0a4ca8833b9438fd
ToppCellcontrol-HLA-DR+_CD83+_Monocyte|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IL13RA1 RXRA NAMPT RASGEF1B MAFB

7.46e-05199975f1b370d2869ad29c9d8ff41fdcc486fffa781ee2
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ANK3 PTH1R TGFB2 GPC4 PCDH18

7.46e-051999756b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell3'_v3-blood-Myeloid_Monocytic-Classical_monocytes|blood / Manually curated celltypes from each tissue

IL13RA1 JDP2 RXRA NAMPT MAFB

7.46e-0519997595b27f4bf1300f885b95c1a70a54252274dc8f51
ToppCellParenchyma_Control_(B.)-Immune-TX-MoAM-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CREM NAMPT MAFB MX2 SORL1

7.64e-0520097559b2ebb69699c9bebf8c2697eb678fdccd0a998c
ToppCellBronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PEG3 PTH1R KCNJ6 GPC4 UNC5D

7.64e-0520097512326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCellmild-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

RXRA NAMPT RASGEF1B MAFB PLEC

7.64e-05200975934c2efc780318c66d667ca75be0de350361d351
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CEP85L AFF3 PCDH17 CCNY ADGRL2

7.64e-05200975bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCellLung_Parenchyma-Control-Myeloid-MoAM-MoAM-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CREM NAMPT MAFB MX2 SORL1

7.64e-05200975390f9429feae991b8524e2815d8fcd4914c74459
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MYO9A PTH1R TGFB2 SMARCA4 PLXNA1

7.64e-05200975ddfb1f006365bf16203ee49f20200f68220cc288
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CEP85L AFF3 PCDH17 CCNY ADGRL2

7.64e-05200975b7533c571eeea0cb3678e1a57d3dc036fa8d0f49
ToppCellLPS_IL1RA-Endothelial-Endothelial-Alv_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

AFF3 PCDH17 CCNY PLEC ADGRL2

7.64e-052009757034f57e282982c19c13ee8ab78eabaffa069e30
ToppCellLPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PCDH17 CCNY SMARCA2 PLEC ADGRL2

7.64e-05200975b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

PTH1R TGFB2 GPC4 PAK3 PCDH18

7.64e-05200975a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCellcontrol-Neutrophil|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

JDP2 RXRA CCNY NAMPT MAFB

7.64e-05200975b5d197472799cc61d7497faed91ac2564ae4930a
ToppCellmild-B_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IKZF3 BEND5 AFF3 STX7 EIF2AK3

7.64e-05200975222789b897e2a683bbfd1d00b6fd8705015d90df
ToppCellLung_Parenchyma-Control-Myeloid-MoAM-MoAM|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CREM NAMPT MAFB MX2 SORL1

7.64e-05200975f7e9b4a8ededb116774528b38ea3381b6f05915c
ToppCellsevere-Non-classical_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

JDP2 RXRA NAMPT RASGEF1B MAFB

7.64e-05200975804c6e998fb7a29ca1b98f53d5dbcb7ae5a47e7a
ToppCellLung_Parenchyma-Control-Myeloid-MoAM|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CREM NAMPT MAFB MX2 SORL1

7.64e-05200975d98c523ac0e4767aaeef50cae142513d115212ab
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-B|COVID-19_Mild / Disease, condition lineage and cell class

IKZF3 BEND5 AFF3 STX7 EIF2AK3

7.64e-0520097511b51dfca161342d92126e0a83d10864348ba3ef
ToppCellmild-B_naive|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

IKZF3 BEND5 AFF3 STX7 EIF2AK3

7.64e-05200975d0467cab6a42bf780aa49046bf3231ca161dc144
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Adora2a|Striatum / BrainAtlas - Mouse McCarroll V32

IKZF3 ZNF804A MYO3B ABCC12

9.50e-05109974e8e0f2c5f8c9e45f2b4d173569c94275eedfe432
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3_(Neuron.Gad1Gad2.Cplx3)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

USP26 MYO3A MYO3B

2.10e-04539739c6aba539d540211b2309da1af6a531f3275a49d
ToppCellFrontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3_(Neuron.Gad1Gad2.Cplx3)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

USP26 MYO3A MYO3B

2.10e-0453973846e031024ad3a4f5c6640b61cf4a0e69dbbcd1c
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

ZNF438 RBBP6 ZNF804A JMJD1C

2.16e-041359743351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Itm2a|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZNF804A HOXA13 MAFB NXPH2

2.77e-041449740bbe670454846cf9bc7464ae4e91488415c4111d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAMTSL1 SLC35F3 KCNJ6 NXPH2

2.92e-04146974ec1f793409d1a81c0f9323eb3c82ffe01dae0e44
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

BEND5 WNT9A CARD9 UNC5D

3.15e-041499744b44108c40376a6b73258df40d2424e68f991383
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-9|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

BEND5 AFF3 ZNF395 GPC4

3.32e-041519742314c004434aed9b7fa1ad01c61c43e5ed4a18ce
ToppCellsaliva-Mild-Moderate_progression_d12-25-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCDH17 NAMPT MX2 SORL1

3.32e-04151974b698ddc74565d47892c09c3f16d78038da2dd5e7
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Ntn1_Npy2r|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCDH17 MYO3B GPC4 PCDH18

3.40e-041529748ff5a178a8f3550d89a003c0858820aab3773386
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

PCDH17 TGFB2 MYO3A MYO3B

3.40e-04152974fed80b467ec9e30c7f98bed6cc4f8c583b715e9e
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR2B MYO3B PAK3 FGFBP1

3.57e-041549741e32969bee810adaf2d560f0824a16227df513d8
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-neuro-epithelial-EC_cells_(NPW+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA13 SLC35F3 TTLL6 KCNJ6

3.66e-04155974498e52e2364ff44d3c0c707ba22468217031f5bd
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AFF3 ZNF804A MYO3B SORL1

3.75e-04156974203ef22eb76bd2b829b027c30af0557080f4006c
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

WNT9A RASGEF1B ADGRL2 UNC5D

4.03e-04159974a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCelldroplet-Heart-nan-24m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATXN7L2 PCDH18 PLXNA1 SORL1

4.03e-041599747ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-astrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATXN7L2 CCDC146 BEND5 SORL1

4.23e-041619749f02b94e29e60d50e92eaa748ebf0c36d3671bb3
ToppCellHealthy_Control-Lymphoid-B-|Healthy_Control / Condition, Lineage, Cell class and cell subclass

IKZF3 BEND5 AFF3 GRAMD1C

4.43e-04163974d84bd41b4494c7d5c7f88d511bfe481fb12f079d
ToppCellHealthy_Control-Lymphoid-B|Healthy_Control / Condition, Lineage, Cell class and cell subclass

IKZF3 BEND5 AFF3 GRAMD1C

4.43e-041639740f723ec2503afa1b3ebb0754972438ffb6e6179d
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Reln_Tac1|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ZNF804A PTH1R MAFB NXPH2

4.63e-04165974d8df50f5a3b646e8ea13739fdc65ce6f39b4d4d2
ToppCell(0)_Myeloid-(00)_Monocyte-(000)_CD14+_Monocyte|(00)_Monocyte / immune cells in Peripheral Blood (logTPM normalization)

IL13RA1 CCNY NAMPT SORL1

4.85e-041679747d9fd6a7a45c2aa0d5f2e3960ca4c97ee8836ba5
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGFB2 MYO3B PAK3 FGFBP1

4.85e-04167974cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IKZF3 BEND5 AFF3 SLC35F3

4.96e-04168974ce9fae8b295c668b0959d5007a8bcd401d80e258
Diseasevital capacity

ZNF438 ADAMTSL1 ZSCAN31 AFF3 WNT9A JMJD1C STX1B TGFB2 CARD9 KCNJ6 BRD4 SMARCA2 ADGRL2 EIF2AK3 PLXNA1

8.20e-0612369415EFO_0004312
Diseaseforced expiratory volume

ADAMTSL1 ZSCAN31 AFF3 JMJD1C STX1B TGFB2 NOL4L CARD9 SMARCA2 ADGRL2 EIF2AK3

4.28e-057899411EFO_0004314
DiseaseClear Cell Sarcoma of Soft Tissue

CREB1 ATF1

6.00e-054942C0206651
DiseaseMENTAL RETARDATION, AUTOSOMAL DOMINANT 12

SMARCA2 SMARCA4

9.98e-055942C3281201
Diseasecognitive function measurement, self reported educational attainment

ATXN7L2 AFF3 ZNF804A JMJD1C PCDH17 PRR12 NOL4L

1.44e-04355947EFO_0004784, EFO_0008354
Diseasephysical activity

OR6B1 ADAMTSL1 RBBP6 CCDC27

1.84e-0488944EFO_0003940
Diseasebirth measurement, spontaneous preterm birth

ADGRL2 SORL1

2.09e-047942EFO_0006917, EFO_0006921
Diseaseopportunistic bacterial infectious disease (implicated_via_orthology)

SMARCA2 SMARCA4

3.56e-049942DOID:0050340 (implicated_via_orthology)
Diseaseaortic aneurysm

IL13RA1 TGFB2

4.44e-0410942EFO_0001666
DiseaseCXCL5 measurement

BRD3 JMJD1C

4.44e-0410942EFO_0009422
DiseaseC-X-C motif chemokine 5 measurement

BRD3 JMJD1C

4.44e-0410942EFO_0008058
Diseasedisposition index measurement, glucose homeostasis measurement

ZNF438 SOHLH2

4.44e-0410942EFO_0006832, EFO_0006896
Diseasediet measurement

OR6B1 ZSCAN31 ANK3 SKIDA1 JMJD1C PCDH17 SMARCA2 SMARCA4 ADGRL2 UNC5D SORL1

5.08e-0410499411EFO_0008111
Diseasefree cholesterol in large LDL measurement

JMJD1C SMARCA4 MAFB

5.84e-0451943EFO_0022176
Diseasemetabolite measurement, body weight gain

TACC2 ACSM4

6.49e-0412942EFO_0004566, EFO_0004725
DiseaseCoffin-Siris syndrome

SMARCA2 SMARCA4

7.65e-0413942C0265338
Diseasecholesterol in IDL measurement

JMJD1C SMARCA4 MAFB

8.51e-0458943EFO_0021899
Diseaseschizophrenia, intelligence, self reported educational attainment

AFF3 BRD3 CREB1 ZNF804A PCDH17 SMARCA2

8.52e-04346946EFO_0004337, EFO_0004784, MONDO_0005090
Diseasetotal lipids in IDL

JMJD1C SMARCA4 MAFB

9.39e-0460943EFO_0022161
Diseaselifestyle measurement

AFF3 ZNF804A PCDH17 RASGEF1B SMARCA2

9.48e-04235945EFO_0010724
Diseasefree cholesterol in IDL measurement

JMJD1C SMARCA4 MAFB

9.86e-0461943EFO_0022181
Diseasesporadic amyotrophic lateral sclerosis

ADAMTSL1 ANK3 ABCC12 PLXNA1

1.06e-03140944EFO_0001357
DiseaseAlzheimer disease, educational attainment

AFF3 JMJD1C PCDH17 SMARCA2 SORL1

1.18e-03247945EFO_0011015, MONDO_0004975
Diseasereaction time measurement

TACC2 RXRA PTH1R PCDH17 BRD4 RASGEF1B CCAR1 ADGRL2

1.21e-03658948EFO_0008393
DiseaseEpstein-Barr virus infection

ARMT1 SLC22A15 SLC35F3

1.24e-0366943EFO_0000769
Diseasedyslexia

CEP85L SMARCA2 ADGRL2 UNC5D

1.82e-03162944EFO_0005424
Diseasecognitive function measurement

ZNF438 ATXN7L2 CCDC146 AFF3 BRD3 ZNF804A JMJD1C RXRA PCDH17 PRR12 MYO3A NOL4L

1.99e-0314349412EFO_0008354
Diseaseneuroimaging measurement

ZNF438 ANK3 AFF3 SKIDA1 TACC2 CREB1 JMJD1C SMARCA2 PLEC EIF2AK3

2.16e-0310699410EFO_0004346
DiseaseDrug toxicity

HTR2B GC ABCC12

2.48e-0384943C0013221
DiseaseAdverse reaction to drug

HTR2B GC ABCC12

2.48e-0384943C0041755
Diseasecup-to-disc ratio measurement

ADAMTSL1 ANK3 TGFB2 NOL4L CCAR1 PLXNA1

2.56e-03430946EFO_0006939
Diseaseintermediate density lipoprotein measurement

JMJD1C SMARCA4 MAFB

2.73e-0387943EFO_0008595
DiseaseS-6-hydroxywarfarin to S-warfarin ratio measurement

GC TACC2 ZNF804A

2.82e-0388943EFO_0803332
DiseaseCrohn's disease

IKZF3 CCDC146 CREM RXRA CCNY CARD9

2.90e-03441946EFO_0000384
Diseasemultiple sclerosis

ZNF438 ADAMTSL1 IKZF3 JDP2 SMARCA4 ATF1 PLEC

2.93e-03594947MONDO_0005301

Protein segments in the cluster

PeptideGeneStartEntry
SRCVSYNREKQLKLK

USP26

211

Q9BXU7
KSCKNEERREAKYNL

BEND5

406

Q7L4P6
KSKRKRKCDNEDDYR

AFF3

816

P51826
CKKTREKASATRVYI

ARMT1

236

Q9H993
IKRKRNSEVKYTEAC

FAM200B

6

P0CF97
TCNYRATKSVKTLRK

HTR2B

396

P41595
LRELERYVKSCLQKK

BRD3

626

Q15059
QKCRLRVSTDLKYRK

GRAMD1C

446

Q8IYS0
VKTRYDTRQRKCPKC

RNF20

946

Q5VTR2
KNKVDDCNYAIKRIR

EIF2AK3

611

Q9NZJ5
ELERYVTSCLRKKRK

BRD4

666

O60885
TKRDDKRDINRYCKE

CCAR1

891

Q8IX12
KRDINRYCKERPSKD

CCAR1

896

Q8IX12
RSQKDICRYSKTAVK

FGFBP1

121

Q14512
QKREKTCRAYLKAIV

ADGRL2

596

O95490
KDILYRLRASKAKCI

ACSM4

151

P0C7M7
DKYKDLRRSARKRSA

CCNY

311

Q8ND76
KESFENYRRKRALRK

CARD9

496

Q9H257
SESIKKRACRYLLQR

ATG2B

6

Q96BY7
EEVAKKRKNLATYCR

ATXN7L2

666

Q5T6C5
SKSICEFDYLRKRRK

CCDC27

191

Q2M243
NCRIEYEKTDRAKKT

NXPH2

186

O95156
KRENKEIRTYNCRIA

PCDH17

731

O14917
REKKDTRSYNCRVAE

PCDH18

726

Q9HCL0
STLYRNTDRQRKKSK

PAK3

246

O75914
RLARERDAYKVKCEK

MAFB

286

Q9Y5Q3
KSKSCSEVRRLYVSK

GPC4

26

O75487
RKIQRYVRKDGKCNV

KCNJ6

51

P48051
CYKAKERKSSRDKEL

JMJD1C

1871

Q15652
AARCRNKKKERTEFL

JDP2

86

Q8WYK2
RDTTRYCEKVKQLKL

ADAMTSL1

1731

Q8N6G6
AYKRKSRDADRTLKR

PLXNA1

1266

Q9UIW2
AYKRKTQDADRTLKR

PLXNA3

1241

P51805
KDNRCRYILKTKFRE

NLRP2

156

Q9NX02
QERARKRIRTYLKSC

NOL4L

231

Q96MY1
NDKSCYSERKKTRNL

RASGEF1B

241

Q0VAM2
SLKRRQKTYNKEKLC

PEG3

671

Q9GZU2
RIRVKTNKLCYEDDK

IL13RA1

311

P78552
EYKKIQKERRRSFSR

RBBP6

671

Q7Z6E9
SYQENCRKRKISSKD

FRG2C

91

A6NGY1
KCLKNEYVENRTKSR

CMC2

46

Q9NRP2
RSRDRKKKSDANASY

ANK3

31

Q12955
KTRDRYISSLKKKCQ

CEP85L

481

Q5SZL2
EAARECRRKKKEYVK

CREB1

281

P16220
YKQRSSLEEHKERCR

IKZF3

211

Q9UKT9
NREAAKECRRRKKEY

CREM

296

Q03060
KTKKLYIDSRARRNL

SEC22B

121

O75396
YLIAKRNRKLKCTFS

SLC22A15

266

Q8IZD6
RTVRKDLTYTCRDNK

RXRA

161

P19793
PSVSCRKRYSKDRKD

LGSN

361

Q5TDP6
VSRLKRRSKDLNCLY

MTBP

731

Q96DY7
KTQKLRYRRCSSELL

PRR14L

1631

Q5THK1
CSFSREKKLDYLKRA

UPP2

231

O95045
DLIRKTDRSYKVKSR

SORL1

1971

Q92673
YKDRIRKKESEVLCS

TDRD6

1161

O60522
NSKAYKRSKRQTLRE

SMARCA2

411

P51531
RAADYQRKSRKTLCI

STX7

226

O15400
SIRKRLKLCADFKRT

TAF1

841

P21675
KRERYISECKKRAEE

ODAD3

296

A5D8V7
LYTSCKTERVLKTKR

SKIDA1

91

Q1XH10
AKAYKRSKRQSLREA

SMARCA4

436

P51532
YFECREKKTENSKLR

NAMPT

36

P43490
KYKNRVRSRISNLKD

TCEA1

186

P23193
ENVNKKDYVRVCARK

PRR12

1651

Q9ULL5
RHLCKKQRSEAYSER

ABCC12

461

Q96J65
RNREVKEALKKLAYC

OR6B1

291

O95007
YATNKFITKDKRRRI

HOXA13

341

P31271
CKSTEKQSVKQRYRE

SLC35F3

121

Q8IY50
RTIRKDLTYSCRDNK

RXRB

231

P28702
KKKKCEIYRRLREFA

CCDC146

501

Q8IYE0
RRKKKEYVKCLENRV

ATF1

231

P18846
RESACQSRRKKKEYL

ATF6B

336

Q99941
TNRRKKRALDAAYCF

TGFB2

296

P61812
SLDSKYRETCKRDSK

ZSCAN31

211

Q96LW9
YRETCKRDSKAEKQQ

ZSCAN31

216

Q96LW9
KECKKTFTLYRNLTR

ZNF573

361

Q86YE8
CRTKFKSLQLSYRKV

ZSCAN32

306

Q9NX65
RCDTRQQYRKLLKST

PTH1R

396

Q03431
CKLYSEQRAIRVKRV

STX18

146

Q9P2W9
TQSKYRDRCKDRIQR

STX1B

136

P61266
RRSKRNRKCPVKFDD

ZBTB41

251

Q5SVQ8
EDRKSVRYTRQKKSL

TRIM15

311

Q9C019
KRYSRSLTIAEFKCK

TBCB

26

Q99426
ARKARGEAKKCRKVY

ZNF395

476

Q9H8N7
ALERGRDYEKNKVCK

GC

16

P02774
KTYKCNECRKTFSRR

ZNF808

481

Q8N4W9
LKRCAQEYLSRVKKE

TACC2

2856

O95359
QKLQEALRRKYSCDR

PLEC

876

Q15149
RKKKRLVINLSSCRY

TTLL6

56

Q8N841
KSRKASVRIAYLRKN

UNC5D

146

Q6UXZ4
RCERFLQKSYRKLEK

WDR93

646

Q6P2C0
YKACDRLKLERKQRR

WNT9A

56

O14904
HSSKEKLRRERIKYC

SOHLH2

206

Q9NX45
RKYIINKCRDGKERV

ZNF438

401

Q7Z4V0
QRYKNISCKIRETEK

ZNF804A

546

Q7Z570
RRRSQFSSRKYLKKE

MX2

11

P20592
CSRRYQKIQEKRKES

MYO3A

1071

Q8NEV4
YDARRKFKKISNRRN

MYO3B

1101

Q8WXR4
RCKEEKYSITRKNPR

MYO9A

761

B2RTY4