Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbenzodiazepine receptor binding

RIMBP3 RIMBP3C RIMBP3B

4.11e-075703GO:0030156
GeneOntologyMolecularFunctiontubulin binding

TTBK2 MAP1A WIPF3 NAV3 RITA1 EML3 MTUS2 PSRC1

1.23e-04428708GO:0015631
GeneOntologyMolecularFunctioncytoskeletal protein binding

MAPK8IP1 TTBK2 CACNB2 TMEM201 MAP1A WIPF3 NAV3 RITA1 PDLIM2 EML3 MTUS2 PSRC1

4.00e-0410997012GO:0008092
GeneOntologyMolecularFunctionmicrotubule binding

TTBK2 MAP1A NAV3 EML3 MTUS2 PSRC1

7.35e-04308706GO:0008017
GeneOntologyMolecularFunctionionotropic glutamate receptor binding

MAP1A AGAP2 NEDD4

8.06e-0452703GO:0035255
GeneOntologyCellularComponentGolgi lumen

SDC3 MUC5B MUC12 MUC4 MUC5AC

3.48e-05109715GO:0005796
GeneOntologyCellularComponentmanchette

RIMBP3 RIMBP3C RIMBP3B

1.16e-0428713GO:0002177
GeneOntologyCellularComponentcentriolar subdistal appendage

CEP170 CCDC120

5.03e-0410712GO:0120103
DomainVWD

MUC5B MUC4 MUC5AC

2.73e-0516703SM00216
DomainVWF_type-D

MUC5B MUC4 MUC5AC

2.73e-0516703IPR001846
DomainVWFD

MUC5B MUC4 MUC5AC

2.73e-0516703PS51233
DomainVWD

MUC5B MUC4 MUC5AC

2.73e-0516703PF00094
DomainHECT

HUWE1 HERC1 NEDD4

1.38e-0427703PF00632
DomainHECTc

HUWE1 HERC1 NEDD4

1.38e-0427703SM00119
DomainHECT_dom

HUWE1 HERC1 NEDD4

1.38e-0427703IPR000569
DomainHECT

HUWE1 HERC1 NEDD4

1.38e-0427703PS50237
DomainWxxW_domain

MUC5B MUC5AC

2.06e-046702IPR025155
DomainMucin2_WxxW

MUC5B MUC5AC

2.06e-046702PF13330
DomainSH3_9

RIMBP3 MAPK8IP1 RIMBP3C RIMBP3B

2.09e-0478704PF14604
DomainSET

KMT2A PRDM6 PRDM1

4.85e-0441703PF00856
DomainE3_UB_ligase_RBR

ANKIB1 RNF217

6.11e-0410702IPR031127
DomainSET

KMT2A PRDM6 PRDM1

6.82e-0446703SM00317
DomainSET_dom

KMT2A PRDM6 PRDM1

8.71e-0450703IPR001214
DomainSET

KMT2A PRDM6 PRDM1

8.71e-0450703PS50280
DomainTIL

MUC5B MUC5AC

8.92e-0412702PF01826
DomainC8

MUC5B MUC5AC

8.92e-0412702PF08742
DomainFN3

RIMBP3 FNDC1 COL20A1 RIMBP3C RIMBP3B

9.02e-04199705PS50853
DomainUnchr_dom_Cys-rich

MUC5B MUC5AC

1.05e-0313702IPR014853
DomainC8

MUC5B MUC5AC

1.05e-0313702SM00832
DomainFN3_dom

RIMBP3 FNDC1 COL20A1 RIMBP3C RIMBP3B

1.12e-03209705IPR003961
DomainIBR

ANKIB1 RNF217

1.22e-0314702SM00647
DomainTIL_dom

MUC5B MUC5AC

1.22e-0314702IPR002919
DomainIBR

ANKIB1 RNF217

1.22e-0314702PF01485
DomainSH3

RIMBP3 MAPK8IP1 CACNB2 RIMBP3C RIMBP3B

1.30e-03216705SM00326
DomainSH3

RIMBP3 MAPK8IP1 CACNB2 RIMBP3C RIMBP3B

1.30e-03216705PS50002
DomainSH3_domain

RIMBP3 MAPK8IP1 CACNB2 RIMBP3C RIMBP3B

1.41e-03220705IPR001452
DomainIBR_dom

ANKIB1 RNF217

1.41e-0315702IPR002867
DomainGlyco_hormone_CN

MUC5B MUC5AC

1.41e-0315702IPR006208
DomainCys_knot

MUC5B MUC5AC

1.41e-0315702PF00007
DomainAT_hook

AHCTF1 KMT2A

1.61e-0316702PF02178
DomainCTCK_1

MUC5B MUC5AC

2.04e-0318702PS01185
DomainVWC_out

MUC5B MUC5AC

2.27e-0319702SM00215
DomainCT

MUC5B MUC5AC

3.05e-0322702SM00041
DomainUIM

ANKIB1 HUWE1

3.62e-0324702PS50330
DomainUIM_dom

ANKIB1 HUWE1

3.93e-0325702IPR003903
DomainCys_knot_C

MUC5B MUC5AC

3.93e-0325702IPR006207
DomainCTCK_2

MUC5B MUC5AC

3.93e-0325702PS01225
DomainSH3_2

RIMBP3 RIMBP3C RIMBP3B

4.13e-0386703IPR011511
DomainSH3_2

RIMBP3 RIMBP3C RIMBP3B

4.13e-0386703PF07653
DomainAT_hook

AHCTF1 KMT2A

4.57e-0327702SM00384
DomainAT_hook_DNA-bd_motif

AHCTF1 KMT2A

4.57e-0327702IPR017956
DomainVWC

MUC5B MUC5AC

4.91e-0328702PF00093
DomainFN3

FNDC1 COL20A1 RIMBP3C RIMBP3B

5.14e-03185704SM00060
DomainVWFC_1

MUC5B MUC5AC

8.03e-0336702PS01208
DomainVWC

MUC5B MUC5AC

8.92e-0338702SM00214
DomainVWFC_2

MUC5B MUC5AC

8.92e-0338702PS50184
DomainVWF_dom

MUC5B MUC5AC

1.08e-0242702IPR001007
PathwayREACTOME_DEFECTIVE_GALNT3_CAUSES_HFTC

MUC5B MUC12 MUC4 MUC5AC

1.75e-0716464M27410
PathwayREACTOME_DEFECTIVE_C1GALT1C1_CAUSES_TNPS

MUC5B MUC12 MUC4 MUC5AC

2.29e-0717464M27412
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC5B MUC12 MUC4 MUC5AC

8.40e-0723464M556
PathwayREACTOME_DECTIN_2_FAMILY

MUC5B MUC12 MUC4 MUC5AC

1.41e-0626464M27483
PathwayREACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS

MUC5B MUC4 MUC5AC

4.15e-0521463MM15706
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC5B MUC12 MUC4 MUC5AC

4.82e-0562464M546
PathwayREACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS

MUC5B MUC12 MUC4 MUC5AC

6.94e-0568464M27303
PathwayREACTOME_DISEASES_OF_GLYCOSYLATION

SDC3 MUC5B MUC12 MUC4 MUC5AC

9.82e-05143465M27275
PathwayREACTOME_RUNX2_REGULATES_CHONDROCYTE_MATURATION

GLI2 RUNX2

1.04e-045462M27804
PathwayREACTOME_O_LINKED_GLYCOSYLATION

MUC5B MUC12 MUC4 MUC5AC

4.61e-04111464M27416
PathwayKEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS

UBE4B HUWE1 HERC1 NEDD4

9.61e-04135464M15247
PathwayREACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS

MUC5B MUC4 MUC5AC

9.77e-0460463MM15636
PathwayREACTOME_C_TYPE_LECTIN_RECEPTORS_CLRS

MUC5B MUC12 MUC4 MUC5AC

1.10e-03140464M27484
Pubmed

RIM-BP3 is a manchette-associated protein essential for spermiogenesis.

RIMBP3 RIMBP3C RIMBP3B

3.40e-08472319091768
Pubmed

Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.

MUC5B MUC12 MUC4 MUC5AC

5.05e-081872418834073
Pubmed

Polymorphism of human mucin genes in chest disease: possible significance of MUC2.

MUC5B MUC4 MUC5AC

8.48e-08572311062147
Pubmed

Structure and evolution of RIM-BP genes: identification of a novel family member.

RIMBP3 RIMBP3C RIMBP3B

8.48e-08572317855024
Pubmed

Integrative characterization of germ cell-specific genes from mouse spermatocyte UniGene library.

RIMBP3 RIMBP3C RIMBP3B

3.05e-061472317662146
Pubmed

Cloning and analysis of cDNA encoding a major airway glycoprotein, human tracheobronchial mucin (MUC5).

MUC5B MUC5AC

4.23e-0627227513696
Pubmed

Airway mucin MUC5AC and MUC5B concentrations and the initiation and progression of chronic obstructive pulmonary disease: an analysis of the SPIROMICS cohort.

MUC5B MUC5AC

4.23e-06272234058148
Pubmed

The association between MUC5AC and MUC5B genes expression and remodeling progression in severe neutrophilic asthma: A direct relationship.

MUC5B MUC5AC

4.23e-06272237146737
Pubmed

MUC5AC and MUC5B Mucins Are Decreased in Cystic Fibrosis Airway Secretions.

MUC5B MUC5AC

4.23e-06272214988081
Pubmed

Mucin glycosylation changes in cystic fibrosis lung disease are not manifest in submucosal gland secretions.

MUC5B MUC5AC

4.23e-06272215563276
Pubmed

The expression of MUC5AC and MUC5B mucin genes in the mucosa of chronic rhinosinusitis and nasal polyposis.

MUC5B MUC5AC

4.23e-06272217621824
Pubmed

MUC4 and MUC5AC are highly specific tumour-associated mucins in biliary tract cancer.

MUC4 MUC5AC

4.23e-06272218475301
Pubmed

Muc5b is required for airway defence.

MUC5B MUC5AC

4.23e-06272224317696
Pubmed

Macrophages are related to goblet cell hyperplasia and induce MUC5B but not MUC5AC in human bronchus epithelial cells.

MUC5B MUC5AC

4.23e-06272222391959
Pubmed

C-Mannosylation of MUC5AC and MUC5B Cys subdomains.

MUC5B MUC5AC

4.23e-06272214718370
Pubmed

Mucins MUC5AC and MUC5B Are Variably Packaged in the Same and in Separate Secretory Granules.

MUC5B MUC5AC

4.23e-06272235776514
Pubmed

The ocular surface phenotype of Muc5ac and Muc5b null mice.

MUC5B MUC5AC

4.23e-06272224327612
Pubmed

Mucin production during prenatal and postnatal murine lung development.

MUC5B MUC5AC

4.23e-06272221653907
Pubmed

MUC5B mobilizes and MUC5AC spatially aligns mucociliary transport on human airway epithelium.

MUC5B MUC5AC

4.23e-06272236427316
Pubmed

Gel-forming mucins form distinct morphologic structures in airways.

MUC5B MUC5AC

4.23e-06272228607090
Pubmed

Mucin deficiency causes functional and structural changes of the ocular surface.

MUC5B MUC5AC

4.23e-06272223272068
Pubmed

Muc5b is mainly expressed and sialylated in the nasal olfactory epithelium whereas Muc5ac is exclusively expressed and fucosylated in the nasal respiratory epithelium.

MUC5B MUC5AC

4.23e-06272231030254
Pubmed

Younger patients with COME are more likely to have mucoid middle ear fluid containing mucin MUC5B.

MUC5B MUC5AC

4.23e-06272227729120
Pubmed

The idiopathic pulmonary fibrosis honeycomb cyst contains a mucocilary pseudostratified epithelium.

MUC5B MUC5AC

4.23e-06272223527003
Pubmed

Up-regulation of MUC5AC and MUC5B mucin genes in nasopharyngeal respiratory mucosa and selective up-regulation of MUC5B in middle ear in pediatric otitis media with effusion.

MUC5B MUC5AC

4.23e-06272216540890
Pubmed

De novo NUF2 variant in a novel inherited bone marrow failure syndrome including microcephaly and renal hypoplasia.

MUC5B MUC5AC

4.23e-06272236111525
Pubmed

Abnormalities in MUC5AC and MUC5B Protein in Airway Mucus in Asthma.

MUC5B MUC5AC

4.23e-06272227845589
Pubmed

Contribution of mucus concentration and secreted mucins Muc5ac and Muc5b to the pathogenesis of muco-obstructive lung disease.

MUC5B MUC5AC

4.23e-06272227435107
Pubmed

Mucins MUC5B and MUC5AC in Distal Airways and Honeycomb Spaces: Comparison among Idiopathic Pulmonary Fibrosis/Usual Interstitial Pneumonia, Fibrotic Nonspecific Interstitial Pneumonitis, and Control Lungs.

MUC5B MUC5AC

4.23e-06272226871672
Pubmed

Expression of mucins in mucoid otitis media.

MUC5B MUC4

4.23e-06272214690056
Pubmed

Normal murine respiratory tract has its mucus concentrated in clouds based on the Muc5b mucin.

MUC5B MUC5AC

4.23e-06272232348677
Pubmed

In silico cloning of mouse Muc5b gene and upregulation of its expression in mouse asthma model.

MUC5B MUC5AC

4.23e-06272211587997
Pubmed

Alteration of ocular surface mucins in MUC5AC-DTA transgenic mice.

MUC4 MUC5AC

4.23e-06272219158956
Pubmed

Reassessment of the importance of mucins in determining sputum properties in cystic fibrosis.

MUC5B MUC5AC

4.23e-06272224332705
Pubmed

Pathophysiological relevance of sputum MUC5AC and MUC5B levels in patients with mild asthma.

MUC5B MUC5AC

4.23e-06272234656442
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

MAPK8IP1 PRKD2 PCYT1A CCDC13 ZSWIM8 CNKSR1 HIVEP2 UBE4B NAV3 HUWE1 MTUS2 AGAP2

1.22e-051285721235914814
Pubmed

Interleukin-33 induces mucin gene expression and goblet cell hyperplasia in human nasal epithelial cells.

MUC5B MUC5AC

1.27e-05372227776277
Pubmed

High-Mobility Group Box 1 Upregulates MUC5AC and MUC5B Expression in Primary Airway Epithelial Cells.

MUC5B MUC5AC

1.27e-05372229286856
Pubmed

Nebulized Menthol Impairs Mucociliary Clearance via TRPM8 and MUC5AC/MUC5B in Primary Airway Epithelial Cells.

MUC5B MUC5AC

1.27e-05372236675209
Pubmed

Th2 cytokines orchestrate the secretion of MUC5AC and MUC5B in IL-5-positive chronic rhinosinusitis with nasal polyps.

MUC5B MUC5AC

1.27e-05372229802623
Pubmed

Ihh/Gli2 signaling promotes osteoblast differentiation by regulating Runx2 expression and function.

GLI2 RUNX2

1.27e-05372217442891
Pubmed

Autophagy of mucin granules contributes to resolution of airway mucous metaplasia.

MUC5B MUC5AC

1.27e-05372234158522
Pubmed

Resistin upregulates MUC5AC/B mucin gene expression in human airway epithelial cells.

MUC5B MUC5AC

1.27e-05372229604272
Pubmed

IL-8 regulates mucin gene expression at the posttranscriptional level in lung epithelial cells.

MUC5B MUC5AC

1.27e-05372219596978
Pubmed

Beraprost ameliorates postmenopausal osteoporosis by regulating Nedd4-induced Runx2 ubiquitination.

RUNX2 NEDD4

1.27e-05372233993186
Pubmed

Recurrent YAP1 and KMT2A Gene Rearrangements in a Subset of MUC4-negative Sclerosing Epithelioid Fibrosarcoma.

KMT2A MUC4

1.27e-05372231592798
Pubmed

Regulation of neuregulin 1beta1-induced MUC5AC and MUC5B expression in human airway epithelium.

MUC5B MUC5AC

1.27e-05372219556605
Pubmed

Clinicopathological and prognostic significance of MUC-2, MUC-4 and MUC-5AC expression in japanese gastric carcinomas.

MUC4 MUC5AC

1.27e-05372223464473
Pubmed

Aquaporin 5 expression increases mucin production in lung adenocarcinoma.

MUC5B MUC5AC

1.27e-05372221455588
Pubmed

Expression of leptin receptor in nasal polyps: leptin as a mucosecretagogue.

MUC5B MUC5AC

1.27e-05372220422702
Pubmed

Mucin gene polymorphisms in otitis media patients.

MUC5B MUC5AC

1.27e-05372219718741
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PRKD2 HIVEP2 EP400 UBE4B NUP214 HUWE1 MAPKBP1 HERC1 EML3 CRAMP1 BAP1

1.63e-051105721135748872
Pubmed

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

HUWE1 HERC1 NEDD4

2.14e-052672326949039
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

EP400 UBE4B NAV3 NUP214 MAPKBP1 SRRM2 NEDD4

2.19e-0540772712693553
Pubmed

ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites.

MUC5B MUC5AC

2.53e-05472231582416
Pubmed

Increased expression of MUC5AC and MUC5B promoting bacterial biofilm formation in chronic rhinosinusitis patients.

MUC5B MUC5AC

2.53e-05472225638393
Pubmed

Epigenetic regulation (DNA methylation, histone modifications) of the 11p15 mucin genes (MUC2, MUC5AC, MUC5B, MUC6) in epithelial cancer cells.

MUC5B MUC5AC

2.53e-05472217471237
Pubmed

MCP-1/CCR2B-dependent loop upregulates MUC5AC and MUC5B in human airway epithelium.

MUC5B MUC5AC

2.53e-05472221097527
Pubmed

Expression of MUC1, MUC2, MUC5AC and MUC5B in mucinous lesions of the breast.

MUC5B MUC5AC

2.53e-05472222269464
Pubmed

The mouse secreted gel-forming mucin gene cluster.

MUC5B MUC5AC

2.53e-05472214984930
Pubmed

TGF-β₂ decreases baseline and IL-13-stimulated mucin production by primary human bronchial epithelial cells.

MUC5B MUC5AC

2.53e-05472223249391
Pubmed

Effects of the Helicobacter pylori Virulence Factor CagA and Ammonium Ion on Mucins in AGS Cells.

MUC5B MUC5AC

2.53e-05472229869461
Pubmed

Munc13-2-/- baseline secretion defect reveals source of oligomeric mucins in mouse airways.

MUC5B MUC5AC

2.53e-05472218258655
Pubmed

SET-NUP214 and MLL cooperatively regulate the promoter activity of the HoxA10 gene.

KMT2A NUP214

2.53e-05472234320268
Pubmed

Expression of MUC2, MUC5AC, MUC5B, and MUC6 mucins in colorectal cancers and their association with the CpG island methylator phenotype.

MUC5B MUC5AC

2.53e-05472223807779
Pubmed

Characterization of mouse muc6 and evidence of conservation of the gel-forming mucin gene cluster between human and mouse.

MUC5B MUC5AC

2.53e-05472212676567
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

CEP170 MAPK8IP1 CCDC13 CACNB2 PRR36 ADGRA1 HUWE1 HCN2 AGAP2 NEDD4

2.87e-05963721028671696
Pubmed

FUS-CREB3L2/L1-positive sarcomas show a specific gene expression profile with upregulation of CD24 and FOXL1.

FOXL1 CREB3L2

4.21e-05572221536545
Pubmed

Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68.

CEP170 CCDC120

4.21e-05572228422092
Pubmed

Activity-Based Probes for HECT E3 Ubiquitin Ligases.

HUWE1 NEDD4

4.21e-05572228425671
Pubmed

Differential expression of MUC genes in endometrial and cervical tissues and tumors.

MUC5B MUC5AC

4.21e-05572216188033
Pubmed

Kif3a deficiency reverses the skeletal abnormalities in Pkd1 deficient mice by restoring the balance between osteogenesis and adipogenesis.

GLI2 RUNX2

4.21e-05572221151991
Pubmed

MUC1, MUC2, MUC4, MUC5AC and MUC6 expression in the progression of prostate cancer.

MUC4 MUC5AC

4.21e-05572216475027
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

ANKIB1 HUWE1 HERC1 NEDD4

4.66e-059572429643511
Pubmed

Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.

PHF1 EP400 AHCTF1 KMT2A NUP214 HUWE1 MUC4

5.37e-0546972727634302
Pubmed

Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TTBK2 ZSWIM8 PPFIA4 ARHGEF15

5.70e-0510072410048485
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

CEP170 ZSWIM8 AHCTF1 KMT2A HELZ NUP214 HUWE1 SRRM2

6.16e-0565372822586326
Pubmed

Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.

MUC5B MUC5AC

6.31e-05672219110483
Pubmed

β-Sheet Augmentation Is a Conserved Mechanism of Priming HECT E3 Ligases for Ubiquitin Ligation.

HUWE1 NEDD4

6.31e-05672229964046
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

PABIR1 CEP170 HIVEP2 KMT2A HELZ PITPNC1 SRRM2 FAM83B NEDD4

7.07e-0586172936931259
Pubmed

Genome-wide association analysis identifies 13 new risk loci for schizophrenia.

CEP170 CACNB2 WBP1L BAP1

7.97e-0510972423974872
Pubmed

FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine.

GLI2 FOXL1

8.82e-05772219049965
Pubmed

Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.

EP400 KMT2A SRRM2

9.22e-054272335705031
Pubmed

A census of human transcription factors: function, expression and evolution.

HIVEP2 GLI2 AHCTF1 KMT2A RUNX2 CRAMP1 FOXL1 CREB3L2 PRDM1

1.06e-0490872919274049
Pubmed

Functional characterization of TIP60 sumoylation in UV-irradiated DNA damage response.

EP400 MTUS2

1.17e-04872217704809
Pubmed

Regulation of Calvarial Osteogenesis by Concomitant De-repression of GLI3 and Activation of IHH Targets.

GLI2 RUNX2

1.51e-04972229311969
Pubmed

Impaired skin and hair follicle development in Runx2 deficient mice.

GLI2 RUNX2

1.51e-04972218262513
Pubmed

U box proteins as a new family of ubiquitin-protein ligases.

UBE4B NEDD4

1.88e-041072211435423
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

EP400 UBE4B KMT2A HELZ NUP214 HUWE1 SRRM2 BAP1

1.98e-0477472815302935
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

RIMBP3 ZSWIM8 MAP1A EP400 HELZ HUWE1 FAM83B

2.17e-0458872738580884
Pubmed

Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study.

MUC5B MUC5AC

2.30e-041172224429156
Pubmed

The murine Bapx1 homeobox gene plays a critical role in embryonic development of the axial skeleton and spleen.

GLI2 RUNX2

2.30e-041172210572046
Pubmed

Role of Indian hedgehog signaling in palatal osteogenesis.

GLI2 RUNX2

2.30e-041172221364421
Pubmed

Respiratory distress and perinatal lethality in Nedd4-2-deficient mice.

MUC5AC NEDD4

2.30e-041172221505443
Pubmed

Gli1 protein participates in Hedgehog-mediated specification of osteoblast lineage during endochondral ossification.

GLI2 RUNX2

2.30e-041172222493482
Pubmed

Runx2 (Cbfa1) inhibits Shh signaling in the lower but not upper molars of mouse embryos and prevents the budding of putative successional teeth.

GLI2 RUNX2

2.30e-041172215668330
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CEP170 CACNB2 HIVEP2 UBE4B GLI2 ANKIB1 SDC3 HUWE1 CRAMP1 CREB3L2 FAM149A

2.34e-041489721128611215
Pubmed

Global phosphoproteome of HT-29 human colon adenocarcinoma cells.

CEP170 PRKD2 SRRM2

2.54e-045972316083285
Pubmed

Cell autonomous roles of Nedd4 in craniofacial bone formation.

RUNX2 NEDD4

2.75e-041272226681395
Pubmed

The ubiquitin ligase Nedd4 regulates craniofacial development by promoting cranial neural crest cell survival and stem-cell like properties.

RUNX2 NEDD4

2.75e-041272224080509
Cytoband22q11.21

RIMBP3 RIMBP3C RIMBP3B

7.27e-0411172322q11.21
Cytoband17q24.2

HELZ PITPNC1

1.03e-033072217q24.2
CytobandEnsembl 112 genes in cytogenetic band chr15q15

TTBK2 MAP1A MAPKBP1

1.63e-03147723chr15q15
GeneFamilyCD molecules|Mucins

MUC5B MUC12 MUC4 MUC5AC

1.61e-0721434648
GeneFamilyZinc fingers C2H2-type|PR/SET domain family

PRDM6 PRDM1

7.35e-04174321197
GeneFamilyNucleoporins

AHCTF1 NUP214

2.62e-03324321051
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

KMT2A PRDM6

2.95e-0334432487
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

EP400 CRAMP1

7.05e-0353432532
CoexpressionGSE44649_WT_VS_MIR155_KO_NAIVE_CD8_TCELL_UP

PILRA GLI2 SDC3 MAPKBP1 SRRM2 C4orf54

1.78e-05198726M9778
CoexpressionGSE17721_LPS_VS_CPG_8H_BMDC_UP

EP400 WBP1L ANKIB1 KMT2A HCN2 PRDM1

1.88e-05200726M4003
ToppCelldroplet-Heart-nan-24m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIAA0408 MAPK8IP1 ZSWIM8 GLI2 PRDM6

5.98e-061597257ad3a91d29639b32f6264c91f401c14a35469ac0
ToppCelldroplet-Thymus-nan-3m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNB2 PILRA PPFIA4 SDC3 FAM149A

9.01e-0617372563f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 CACNB2 FNDC1 GLI2 PRDM6

1.06e-0517972502c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 GLI2 KCNK10 NAV3 PRDM6

1.09e-0518072508ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 HIVEP2 NAV3 RUNX2 PRDM1

1.09e-0518072512537d8a569faa69f474284d2c201475722b8ca1
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 GLI2 KCNK10 NAV3 PRDM6

1.09e-051807259b1de1b4711adbf9a423f4d2d08f3f4c78f1f8f4
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 CACNB2 FNDC1 GLI2 PRDM6

1.18e-051837257eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 GLI2 LRRC4B PRDM6 FOXL1

1.18e-05183725667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 CACNB2 FNDC1 LRRC4B PRDM6

1.18e-0518372512daaea821e49bc94a01e2496331e92a80d27339
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 CACNB2 FNDC1 GLI2 PRDM6

1.25e-051857256712512100ccef456d2e2bd201d0987986c92ac9
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 CACNB2 FNDC1 RUNX2 PRDM6

1.25e-051857253b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCellMild_COVID-19-Epithelial-AT1/AT2|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

CACNB2 PRR36 NAV3 ADGRA1 FAM83B

1.25e-05185725c55fdba1e3818ec0404d7ab473bf18dd25f2bb0a
ToppCellNeuronal_cells-Schwann_cells|World / Lineage and Cell class

MAPK8IP1 CCDC13 MAP1A LRRC4B HCN2

1.38e-05189725371cdc92549269e45c23c5a5b3cae9c5d35ee217
ToppCellNeuronal_cells|World / Lineage and Cell class

MAPK8IP1 CCDC13 MAP1A LRRC4B HCN2

1.38e-051897253948775a0ebd4b32c1623d5487f5581e6e2934d7
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 CACNB2 FNDC1 GLI2 PRDM6

1.38e-0518972545e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 CACNB2 FNDC1 GLI2 PRDM6

1.45e-0519172514057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIAA0408 CACNB2 FNDC1 GLI2 PRDM6

1.45e-05191725b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FNDC1 GLI2 NAV3 RUNX2 PRDM6

1.49e-0519272567e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

CACNB2 FNDC1 GLI2 NAV3 PRDM6

1.57e-0519472503a269f75a481ea54aea8e6444605db8d6df493d
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B KMT2A HUWE1 HERC1 SRRM2

1.61e-051957253e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C2CD4B KMT2A HUWE1 HERC1 SRRM2

1.61e-051957257796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellBronchus_Control_(B.)|World / Sample group, Lineage and Cell type

HIVEP2 MUC5B MUC4 MUC5AC FAM83B

1.69e-05197725b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GLI2 MUC5B RUNX2 MUC4 MUC5AC

1.73e-05198725af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellPBMC-Severe-cDC_8|Severe / Compartment, Disease Groups and Clusters

HROB AHCTF1 HCN2 PSRC1

8.98e-0514572423a9a4fd1934c4a38d9259105c1fdbac459575cb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_atypical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP1A SDC3 LRRC4B FOXL1

9.72e-05148724b7b5521162effc1024e7c399f690cd86d0b2f750
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HROB MUC12 CREB3L2 PRDM1

1.02e-041507248b781ec3e6c2adf052d46d724e2aef72b0c27d13
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HROB MUC12 CREB3L2 PRDM1

1.02e-0415072417da17f01a3d41ac7df20f806e3eae30eca06982
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HROB MUC12 CREB3L2 PRDM1

1.02e-041507248702d5bb419d5e997d388e8f7e0365ba5d1de8d5
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNB2 FNDC1 GLI2 PRDM6

1.11e-041537241524557514668f515ac1bbe847611f564b265b42
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Club|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

MUC5B MUC4 MUC5AC FAM83B

1.25e-0415872403281e87780e3bacd089903383c016d03c373bf7
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 CCDC120 RUNX2 MAPKBP1

1.34e-04161724ed93cb6c133855a5c244821e1a260aae8ab4df9a
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

CACNB2 LRRC4B PRDM6 MTUS2

1.34e-0416172464891f6f2ee1693c8481e951b9346e2f92d602e3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC1 GLI2 C4orf54 AGAP2

1.34e-04161724a7e09cf2ca6cd70d40d08440fe9c5ab9befa1b79
ToppCellVE-mono3|VE / Condition, Cell_class and T cell subcluster

PILRA WIPF3 NAV3 ARHGEF15

1.34e-041617247df3fefc55ab43b897fc78d1f0c7383b10ac33d5
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 CCDC120 RUNX2 MAPKBP1

1.34e-041617240089d7bb305c592392791862a3341fc92af8f3e2
ToppCellVE-mono3-|VE / Condition, Cell_class and T cell subcluster

PILRA WIPF3 NAV3 ARHGEF15

1.34e-041617244e45bf7eceb0ee30dec4d8852778366776ea5a8f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC1 GLI2 C4orf54 AGAP2

1.34e-0416172408920a716f6ec62538e361211455a30ad726d7be
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Myeloid-chondrocyte-like|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 SDC3 ADGRA1 PRDM6

1.38e-04162724b502d6af6868425b5c919740e011330c0d3cf3b8
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNB2 FNDC1 LRRC4B PRDM6

1.44e-04164724e3983f655cdba308fb192182829f17bef99ce0ba
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A KCNK10 RUNX2 HCN2

1.48e-04165724e2a70dd5870fe8708bf630ed3e6eb3f295df0cdf
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNKSR1 TMEM201 MUC5B MUC5AC

1.51e-0416672460060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNKSR1 TMEM201 MUC5B MUC5AC

1.51e-04166724ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCelldroplet-Spleen-nan-3m-Myeloid-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 SDC3 RUNX2 NEDD4

1.51e-04166724c1f18de4a1a2b6cdc703e6d29d136e1134fcbdf3
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CNKSR1 TMEM201 MUC5B MUC5AC

1.51e-041667244586d6725403f879fc96f67be579022587ce1906
ToppCelldroplet-Spleen-nan-3m-Myeloid|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 SDC3 RUNX2 NEDD4

1.51e-0416672494c30d6ca179d0cb02a5ed0093c5a2871e17ae50
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 MAP1A GLI2 FOXL1

1.55e-04167724e228b8373ffd4436e6b944e26d0fadf3ac289b21
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 MAP1A GLI2 FOXL1

1.55e-041677247cb1b11e8e24a10115e46ffbb74889e672a7a026
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 MAP1A GLI2 FOXL1

1.55e-04167724bb53a478b5d821d6d82c15bc4ed075b67682457c
ToppCellTuft-tuft-1|World / Class top

TMEM201 COL20A1 PITPNC1 AGAP2

1.58e-041687248ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCelldroplet-Lung-LUNG-30m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 KCNK10 RUNX2 MUC5AC

1.58e-04168724e156297a7515e785a9e79a9676700bd3a9d92b98
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 KCNK10 RUNX2 MUC5AC

1.58e-0416872432e0bc0873baa13027241063283ef26d2aab56f5
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Classical-8|TCGA-Thryoid / Sample_Type by Project: Shred V9

KIAA0408 SDC3 RUNX2 EML3

1.58e-0416872400646601548b0fee42ae16bfa5e93603bc7c5129
ToppCellClub_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

GLI2 MUC5B MUC4 MUC5AC

1.62e-0416972403b303af8a26c6ff196507fe24f5bd3d75d7b1af
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR1 C2CD4B SDC3 MUC4

1.66e-04170724a121e10099faaeb60251eec162f38caf7c4238c2
ToppCelldroplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 KCNK10 RUNX2 MUC5AC

1.66e-04170724749144a1a869a6bf9acdd227184319083367dc3f
ToppCelldroplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PPFIA4 KCNK10 RUNX2 MUC5AC

1.66e-0417072425d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCellPericytes-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

GLI2 WIPF3 MTUS2 FOXL1

1.69e-04171724bbc8d9fc83d37c9250345b1e76776610799de9ae
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPFIA4 KCNK10 RUNX2 MUC5AC

1.73e-04172724422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

CACNB2 LRRC4B PRDM6 FOXL1

1.73e-04172724c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellfacs-Marrow-B-cells-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WIPF3 CCDC120 CREB3L2 PRDM1

1.73e-04172724a7fd4d61fb5017dce001d69d6b9a01e6cdf58828
ToppCelldroplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPFIA4 KCNK10 RUNX2 MUC5AC

1.73e-041727241abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPFIA4 KCNK10 RUNX2 MUC5AC

1.77e-041737244f0c065e876197ad8cae7856669f09e37ecafa3f
ToppCelldroplet-Lung-30m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PPFIA4 KCNK10 RUNX2 MUC5AC

1.77e-041737249bbea566964281f47bf75d665b7d69ba8326e207
ToppCellChildren_(3_yrs)-Immune-natural_killer_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

COL20A1 RUNX2 PITPNC1 AGAP2

1.81e-0417472433d6b81f31bfcb9c4b30206d88e20b9a94fba4a2
ToppCell10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages|bone_marrow / Manually curated celltypes from each tissue

RIMBP3 PABIR1 CNKSR1 SDC3

1.81e-041747240746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCellCOPD-Myeloid-pDC|World / Disease state, Lineage and Cell class

MAP1A KCNK10 RUNX2 CREB3L2

1.81e-04174724be8227398300711ccda5ecc41ad34064bb246b19
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 GLI2 PRDM6 FOXL1

1.85e-04175724d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRR36 MUC5B MUC12 MUC4

1.85e-04175724019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 GLI2 PRDM6 FOXL1

1.85e-04175724454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellIPF-Myeloid-pDC|World / Disease state, Lineage and Cell class

MAP1A KCNK10 RUNX2 CREB3L2

1.85e-04175724a06785a4ded01adfd29ca4c20f7759eccbe274cb
ToppCelldroplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNKSR1 C2CD4B SDC3 MUC4

1.85e-04175724f7cd2ef79d91d64976fcdb5f1e7343b24ba27456
ToppCellHippocampus|World / BrainAtlas - Mouse McCarroll V32

C2CD4B PRR36 WIPF3 PSRC1

1.89e-04176724f120a703f6d2f2d5f55eae1aea2e6382a485828f
ToppCellChildren_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNB2 FNDC1 GLI2 PRDM6

1.93e-04177724b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|World / Cell class and subclass of bone marrow stroma cells in homeostatis

KIAA0408 PPFIA4 SDC3 MTUS2

1.98e-04178724c569a406c3ae183a278d8540e8eba58f4f26c5b0
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PRR36 MUC5B MUC12 MUC4

1.98e-041787249099b47e0756d6a1b7ba1c6aa7b47c5425f649e0
ToppCellIPF-Myeloid-pDC|IPF / Disease state, Lineage and Cell class

MAP1A KCNK10 RUNX2 CREB3L2

1.98e-041787248d9e28492e1f157bac3308aa947fd864ca16d277
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 PPFIA4 WIPF3 PDLIM2

2.02e-041797247394e77e665bf16d3733df91bb12907be460ab44
ToppCellCOPD-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

MAP1A KCNK10 RUNX2 CREB3L2

2.02e-0417972429b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCellIPF-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

MAP1A KCNK10 RUNX2 CREB3L2

2.06e-041807240f8567aa835d4e3a52f6631ae15216eca18a030c
ToppCell(3)_Chondrocytes-(32)_Chondro-prehyper-2|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis

KIAA0408 PPFIA4 RUNX2 MTUS2

2.06e-04180724708a5c89b9337e281fce4f482892a1c1766c7812
ToppCellCiliated_cells-A-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

MAP1A MUC5B MUC4 MUC5AC

2.06e-04180724d9be152773fe9f2160edad9246fa03c03afeafd6
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNB2 GLI2 KCNK10 PRDM6

2.11e-041817249e7d0f1afb8d9bc5a209ddb5314df3a25a0274d9
ToppCellfacs-Marrow-T-cells-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUWE1 HCN2 CREB3L2 PRDM1

2.11e-0418172457f0cc749ae8b6a3d77e2af31f9a6e4739c57049
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC1 MAP1A GLI2 NAV3

2.11e-04181724c6d2a13df3b74fade3b0c71e285b4c14c8e52413
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 MAP1A COL20A1 NAV3

2.11e-041817240b1e7335648823b1d83bdfa878ccd44efe7bba9a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 PPFIA4 WIPF3 PDLIM2

2.11e-041817245bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FNDC1 MAP1A GLI2 NAV3

2.11e-04181724c62b0a2422377ffadaab63edd538e87a06fa5017
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB2 PPFIA4 WIPF3 PDLIM2

2.11e-041817248e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellfacs-Marrow-T-cells-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUWE1 HCN2 CREB3L2 PRDM1

2.11e-04181724d01b35cc2fc57991a35be6a06cb7351fbabd9a11
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 GLI2 ADGRA1 PSRC1

2.15e-04182724904804813849b7f7f716ba1554d33b07bc0a701e
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KMT2A RUNX2 CREB3L2 PRDM1

2.15e-04182724626aabfd9ac662c1d189f7c4b660482914d9e669
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L1-3_PVALB_WFDC2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RUNX2 ARHGEF15 NEDD4 PRDM1

2.15e-04182724f00eec1f434d92d44787d3d3343476c98c3de5b4
ToppCelldroplet-Kidney-nan-18m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 C2CD4B COL20A1 WIPF3

2.15e-04182724e3248d108b51c49ca2c978636e13017e23b53860
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KMT2A RUNX2 CREB3L2 PRDM1

2.15e-04182724a00abff41c12b71d5860c494b8c722d649fd5f36
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNDC1 GLI2 ADGRA1 PSRC1

2.15e-041827245d8b7fe18286e27f0f50c5d2d9be56850e2cb8f4
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

PCYT1A GLI2 WIPF3 FAM83B

2.24e-04184724ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC13 WIPF3 CREB3L2 PRDM1

2.24e-041847241da7936a2616986efd5de601ad525f1f2355128a
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MUC5B SRRM2 MUC4 MUC5AC

2.24e-0418472401c19a830348ab0b9c02c1546a439de70ee10f97
ToppCellLeuk-UTI-Other-RBC|Leuk-UTI / Disease, Lineage and Cell Type

HROB MAP1A KCNK10 RUNX2

2.29e-041857245b5dd856d6efc0539d92533cff134bbc3f98be45
ToppCell(7)_MNP-(7)_DC_plasmacytoid|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)

MAP1A KCNK10 RUNX2 CREB3L2

2.29e-041857249f67f652488e17075a372e2a2e1100f6d0af6d7d
Diseasemucinous adenocarcinoma (is_marker_for)

MUC4 MUC5AC

4.76e-055652DOID:3030 (is_marker_for)
Diseasecoronary artery disease

PHF1 PRKD2 FNDC1 HIVEP2 WBP1L RUNX2 PRDM6 PSRC1 FAM83B FOXL1 NEDD4

5.47e-0511946511EFO_0001645
Diseasebiliary tract benign neoplasm (is_marker_for)

MUC4 MUC5AC

9.96e-057652DOID:0050625 (is_marker_for)
Diseasecommon bile duct neoplasm (is_marker_for)

MUC4 MUC5AC

1.33e-048652DOID:4608 (is_marker_for)
Diseaseotitis media (is_marker_for)

MUC5B MUC4

2.13e-0410652DOID:10754 (is_marker_for)
Diseasemetabolic rate measurement

CACNB2 FOXL1

2.59e-0411652EFO_0005115
Diseasepulmonary fibrosis

MUC5B MUC5AC

2.59e-0411652EFO_0009448
Diseasepancreatic ductal carcinoma (is_marker_for)

MUC5B MUC4 MUC5AC

3.35e-0461653DOID:3587 (is_marker_for)
Diseasecholangiocarcinoma (is_marker_for)

MUC5B MUC4 MUC5AC

3.86e-0464653DOID:4947 (is_marker_for)
Diseaseotitis media (biomarker_via_orthology)

MUC4 MUC5AC

6.36e-0417652DOID:10754 (biomarker_via_orthology)
Diseaseatrial fibrillation

UBE4B PPFIA4 HERC1 PRDM6 CRAMP1

1.36e-03371655EFO_0000275
Diseasegastroesophageal reflux disease

HIVEP2 NAV3 ADGRA1

1.46e-03101653EFO_0003948
DiseasePigmented Basal Cell Carcinoma

GLI2 BAP1

1.74e-0328652C1368275
DiseaseCarcinoma, Basal Cell

GLI2 BAP1

1.87e-0329652C4721806
Diseasejoint hypermobility measurement

FNDC1 NEDD4

2.41e-0333652EFO_0007905
DiseaseCOVID-19 symptoms measurement

MUC5B MUC5AC

2.71e-0335652EFO_0600019
DiseasePapillary Renal Cell Carcinoma

NAV3 MUC4 BAP1

2.86e-03128653C1306837
DiseaseRenal Cell Carcinoma

NAV3 MUC4 BAP1

2.86e-03128653C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

NAV3 MUC4 BAP1

2.86e-03128653C1266043

Protein segments in the cluster

PeptideGeneStartEntry
SSKSTTLPRPRPTRT

CEP170

1086

Q5SW79
RPLPTSSTSSLAPVS

EP400

696

Q96L91
GSPRSSRTDSPPSSL

ADGRA1

446

Q86SQ6
IRSANPTRPSSPVTS

BAP1

511

Q92560
TLPSPRTPRTTRSSV

ANKIB1

301

Q9P2G1
AATTPSITATPSPRR

AGAP2

1161

Q99490
STPTPSPVSRRSASP

ARHGEF15

96

O94989
LSRTLATSSLPLSPT

CACNB2

476

Q08289
PPASSSVTAPRRSLL

MTUS2

911

Q5JR59
TRTSTLLPSSPTSAP

MUC5B

2291

Q9HC84
RTSTLLPSSPTSAPI

MUC5B

4106

Q9HC84
RPSSPDTSTPGSRRL

RIMBP3B

311

A6NNM3
RPSSPDTSTPGSRRL

RIMBP3C

311

A6NJZ7
RRTATSPPPTTSQTI

MUC4

4276

Q99102
SRAPPRPRSTTSQVT

MAP1A

2641

P78559
RSPSTTRPTSPTSLC

NEDD4

271

P46934
DSPSASRRSPAPLLS

FAM149A

61

A5PLN7
PPPRASLSSDTSALS

MAPK8IP1

361

Q9UQF2
PPLSGRSTPKLTSRS

PPFIA4

641

O75335
TRRAQTPPISSLPTS

HERC1

2696

Q15751
ESPARAPSSSPLSSR

C2CD4B

216

A6NLJ0
VASPTSPTRSLPRSA

CCDC120

281

Q96HB5
RPTSSPRPTSSELLR

FAM83B

911

Q5T0W9
SSSPTRERSPSPSFR

PCYT1A

321

P49585
RSLPRPSKSSTSGIP

NAV3

1136

Q8IVL0
ASRSPSAPPALRRTT

KIAA0408

666

Q6ZU52
TTELLPRRPPSSSSS

PRKD2

226

Q9BZL6
RPPFSQLPSKSRSSS

LMLN2

36

A0A1B0GTW7
TPPVRSTAPASLSRS

NUP214

956

P35658
RPRTPNSSCSTPSRT

HROB

316

Q8N3J3
SSRLTTPRNSLTLPS

GLI2

1541

P10070
APTPTPRLSISSRAT

KCNK10

36

P57789
TSPRTRLPTASASLP

MUC5AC

1366

P98088
RSTPSPSSLTPRLRS

PSRC1

136

Q6PGN9
PSPTTRFTTRRSQSP

PABIR1

176

Q96E09
PLSSRTVSSSSLPSL

HELZ

1731

P42694
IRPPTRTAPSTNSSA

HUWE1

2991

Q7Z6Z7
PDSLRPRPASLSSAS

PRDM6

66

Q9NQX0
SLALSSSTSPRAPPS

PILRA

271

Q9UKJ1
SLRYTPSTVSRSPPS

COL20A1

731

Q9P218
PTTTTPRPTTATTRR

FNDC1

1461

Q4ZHG4
SALTRPSLPSPHRTS

CCDC13

516

Q8IYE1
PLSSSESSSTRLSPP

CRAMP1

1056

Q96RY5
QTRPLREPSPSSSSL

MAPKBP1

1106

O60336
GSPLRPASRSSPKSS

FOXL1

241

Q12952
RLSSSELSPLTPPSS

KMT2A

761

Q03164
SILRSTLRSTPLASP

AHCTF1

1201

Q8WYP5
TPSRTPSLSPASSLD

EML3

881

Q32P44
TTRTPSPTSSDLARP

C4orf54

441

D6RIA3
TATSRPRALPRPATT

SDC3

251

O75056
ASTRPASSSTPRLGP

HCN2

836

Q9UL51
SRAAPRAPSALSSSP

CREB3L2

236

Q70SY1
SSTTAPAPRSSRPTE

LRRC4B

536

Q9NT99
SSSSVSSPSPGLPRR

PHF1

496

O43189
PSTSRRFSPPSSSLQ

RUNX2

21

Q13950
PSPSRVTSRTTPRRS

SRRM2

936

Q9UQ35
PRTPSRERSSSASSP

SRRM2

1411

Q9UQ35
RPSSPDTSTPGSRRL

RIMBP3

311

Q9UFD9
STTEPSPAARRRPSA

PRR36

216

Q9H6K5
RPASRSLSSSATPLS

PRR36

236

Q9H6K5
RSPIPSSTTPSPSAR

PRDM1

326

O75626
PSAPPVSTDTSSLRR

WIPF3

26

A6NGB9
RSSFPSPRLSLPTDS

RNF217

201

Q8TC41
STSVRASTPTRTPTP

SELENOV

16

P59797
LPSSLSPQSSLPASR

PDLIM2

261

Q96JY6
ETTPSRGSTPTLTPR

RITA1

81

Q96K30
TSPAATPTQRSPRTS

CNKSR1

551

Q969H4
RSSSLPPASTSTLRP

SPEM2

476

Q0P670
PPASTSTLRPSLHRS

SPEM2

481

Q0P670
PASPSATSRRPSSLR

UBE4B

381

O95155
ATSRRPSSLRISPSL

UBE4B

386

O95155
VPRRSPSASPRSSSL

TTBK2

1146

Q6IQ55
ASPTRTPPRESLRTS

nan

211

Q9UF83
TPSRASLTGTPPRAS

nan

366

Q9UF83
SLTRTPPRASLTRTP

nan

416

Q9UF83
PRASLTRTPPRASLT

nan

431

Q9UF83
PSRASLTRTPSRASL

nan

466

Q9UF83
SLTRTPPTASLTRSP

nan

506

Q9UF83
LTRSPPTASLTRTPS

nan

516

Q9UF83
SSVRSAPSSAPSTPL

PITPNC1

266

Q9UKF7
SPRRTSPSSLPGRLS

TMEM201

436

Q5SNT2
TPSRASLTRTPPTAS

nan

91

A8MUU9
SLTRTPPTASRTRSL

nan

96

A8MUU9
PSRASLTRTPPTASL

nan

191

A8MUU9
LTRTPPTASLTRASR

nan

196

A8MUU9
PTASLTRASRTRTPP

nan

201

A8MUU9
SLTRTPSRASLTRTP

nan

236

A8MUU9
PSRASLTRTPSRASL

nan

241

A8MUU9
RTPSRASLTRTPPTA

nan

266

A8MUU9
SLTRTPPTASLTRTP

nan

281

A8MUU9
PRASLTRSPPRASLT

nan

296

A8MUU9
RASLTRTPPTASLTR

nan

306

A8MUU9
ASLTRSPPTASLTRT

nan

316

A8MUU9
SLTRTPPRASLTRSP

nan

326

A8MUU9
LTRSPPRASLTRTPS

nan

336

A8MUU9
PRASLTRTPSTASLT

nan

341

A8MUU9
PSRASLTRTPPRASL

nan

376

A8MUU9
PRASLTRTPPRASLT

nan

386

A8MUU9
RASLTRSPPTASLTR

nan

396

A8MUU9
SLTRSPPRASLTRTP

nan

416

A8MUU9
LTRTPPRASLTRSPS

nan

426

A8MUU9
PRASLTRSPSTASLT

nan

431

A8MUU9
TRSPSTASLTRTPPG

nan

436

A8MUU9
SLTRTPPTASLTRTP

nan

461

A8MUU9
TTSDSSPTLSRRPLR

ZSWIM8

1151

A7E2V4
STLSLSRPSPSATLT

nan

186

Q8N1Y9
TRSRSTSPQPPRFSS

HIVEP2

1931

P31629
LSEPSRSSTRPPSIA

WBP1L

161

Q9NX94
SPRSPDRTLSPARTT

MUC12

286

Q9UKN1
PSRLSPSSTETTTLP

MUC12

2971

Q9UKN1