Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ligand-gated calcium channel activity	TRPM4 RYR2 RYR3 ITPR2	1.70e-04	31	181	4	GO:0099604
GeneOntologyMolecularFunction	insulin receptor activity	INSRR IGF1R	2.44e-04	3	181	2	GO:0005009
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR2 RYR3	4.84e-04	4	181	2	GO:0005219
GeneOntologyMolecularFunction	pyrroline-5-carboxylate reductase activity	PYCR1 PYCR2	4.84e-04	4	181	2	GO:0004735
GeneOntologyMolecularFunction	intracellularly gated calcium channel activity	RYR2 RYR3 ITPR2	5.41e-04	18	181	3	GO:0015278
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH1 DNAH5 DNAH8	5.41e-04	18	181	3	GO:0008569
GeneOntologyCellularComponent	Set3 complex	KMT2E SETD5	7.13e-05	2	177	2	GO:0034967
GeneOntologyCellularComponent	Rpd3L-Expanded complex	KMT2E SETD5	7.13e-05	2	177	2	GO:0070210
GeneOntologyCellularComponent	euchromatin	SETD1A KMT2E SETD5 CTR9 DNTT	3.64e-04	72	177	5	GO:0000791
GeneOntologyCellularComponent	insulin receptor complex	INSRR IGF1R	4.23e-04	4	177	2	GO:0005899
Domain	ARM-type_fold	STK36 RELCH USP9X RTTN NCBP1 ODAD2 MEI1 RYR3 ITPR2 PPP2R1A AP2A2 PIK3CD IPO13 CTNND2 GCN1	1.23e-06	339	182	15	IPR016024
Domain	RIH_assoc-dom	RYR2 RYR3 ITPR2	1.78e-05	6	182	3	IPR013662
Domain	Ins145_P3_rec	RYR2 RYR3 ITPR2	1.78e-05	6	182	3	PF08709
Domain	RIH_assoc	RYR2 RYR3 ITPR2	1.78e-05	6	182	3	PF08454
Domain	RIH_dom	RYR2 RYR3 ITPR2	1.78e-05	6	182	3	IPR000699
Domain	Ins145_P3_rcpt	RYR2 RYR3 ITPR2	1.78e-05	6	182	3	IPR014821
Domain	Ryanodine_recept-rel	RYR2 RYR3 ITPR2	1.78e-05	6	182	3	IPR015925
Domain	-	RYR2 RYR3 ITPR2	1.78e-05	6	182	3	1.25.10.30
Domain	RYDR_ITPR	RYR2 RYR3 ITPR2	1.78e-05	6	182	3	PF01365
Domain	-	STK36 RELCH USP9X RTTN ODAD2 PPP2R1A AP2A2 IPO13 CTNND2 GCN1	6.63e-05	222	182	10	1.25.10.10
Domain	ARM-like	STK36 RELCH USP9X RTTN ODAD2 MEI1 PPP2R1A AP2A2 IPO13 CTNND2 GCN1	7.11e-05	270	182	11	IPR011989
Domain	-	COL6A2 SEC24A ITGB4 ITIH5 SEC24B COL14A1	8.43e-05	74	182	6	3.40.50.410
Domain	MIR	RYR2 RYR3 ITPR2	1.04e-04	10	182	3	PF02815
Domain	MIR_motif	RYR2 RYR3 ITPR2	1.04e-04	10	182	3	IPR016093
Domain	MIR	RYR2 RYR3 ITPR2	1.04e-04	10	182	3	PS50919
Domain	MIR	RYR2 RYR3 ITPR2	1.04e-04	10	182	3	SM00472
Domain	Oxysterol-bd_CS	OSBP OSBPL1A OSBP2	1.88e-04	12	182	3	IPR018494
Domain	Oxysterol_BP	OSBP OSBPL1A OSBP2	1.88e-04	12	182	3	PF01237
Domain	Oxysterol-bd	OSBP OSBPL1A OSBP2	1.88e-04	12	182	3	IPR000648
Domain	OSBP	OSBP OSBPL1A OSBP2	1.88e-04	12	182	3	PS01013
Domain	HEAT	STK36 ODAD2 PPP2R1A IPO13 GCN1	2.51e-04	58	182	5	IPR000357
Domain	Ryanodine_rcpt	RYR2 RYR3	2.82e-04	3	182	2	IPR003032
Domain	-	PYCR1 PYCR2	2.82e-04	3	182	2	1.10.3730.10
Domain	P5CR_dimer	PYCR1 PYCR2	2.82e-04	3	182	2	PF14748
Domain	Ryanrecept_TM4-6	RYR2 RYR3	2.82e-04	3	182	2	IPR009460
Domain	P5CR_dimer	PYCR1 PYCR2	2.82e-04	3	182	2	IPR029036
Domain	RyR	RYR2 RYR3	2.82e-04	3	182	2	PF02026
Domain	Tyr_kinase_insulin-like_rcpt	INSRR IGF1R	2.82e-04	3	182	2	IPR016246
Domain	RR_TM4-6	RYR2 RYR3	2.82e-04	3	182	2	PF06459
Domain	Ryan_recept	RYR2 RYR3	2.82e-04	3	182	2	IPR013333
Domain	Dynein_heavy_chain_D4_dom	DNAH1 DNAH5 DNAH8	3.06e-04	14	182	3	IPR024317
Domain	Dynein_HC_stalk	DNAH1 DNAH5 DNAH8	3.06e-04	14	182	3	IPR024743
Domain	Dynein_heavy_dom-2	DNAH1 DNAH5 DNAH8	3.06e-04	14	182	3	IPR013602
Domain	DHC_N2	DNAH1 DNAH5 DNAH8	3.06e-04	14	182	3	PF08393
Domain	ATPase_dyneun-rel_AAA	DNAH1 DNAH5 DNAH8	3.06e-04	14	182	3	IPR011704
Domain	MT	DNAH1 DNAH5 DNAH8	3.06e-04	14	182	3	PF12777
Domain	AAA_8	DNAH1 DNAH5 DNAH8	3.06e-04	14	182	3	PF12780
Domain	AAA_5	DNAH1 DNAH5 DNAH8	3.06e-04	14	182	3	PF07728
Domain	DHC_fam	DNAH1 DNAH5 DNAH8	3.80e-04	15	182	3	IPR026983
Domain	Dynein_heavy	DNAH1 DNAH5 DNAH8	3.80e-04	15	182	3	PF03028
Domain	Dynein_heavy_dom	DNAH1 DNAH5 DNAH8	3.80e-04	15	182	3	IPR004273
Domain	VWF_A	COL6A2 SEC24A ITGB4 ITIH5 SEC24B COL14A1	4.17e-04	99	182	6	IPR002035
Domain	P5CR	PYCR1 PYCR2	5.59e-04	4	182	2	PS00521
Domain	Pyrroline-COOH_reductase	PYCR1 PYCR2	5.59e-04	4	182	2	IPR000304
Domain	Tap_RNA_bd	NXF5 NXF1	5.59e-04	4	182	2	PD043466
Domain	Tap_RNA-bd	NXF5 NXF1	5.59e-04	4	182	2	IPR015245
Domain	Tap-RNA_bind	NXF5 NXF1	5.59e-04	4	182	2	PF09162
Domain	HEAT_type_2	RELCH PPP2R1A GCN1	5.60e-04	17	182	3	IPR021133
Domain	HEAT_REPEAT	RELCH ODAD2 PPP2R1A IPO13 GCN1	6.03e-04	70	182	5	PS50077
Domain	Sec23/24_helical_dom	SEC24A SEC24B	1.38e-03	6	182	2	IPR006900
Domain	Sec23_24_beta_S	SEC24A SEC24B	1.38e-03	6	182	2	IPR012990
Domain	zf-Sec23_Sec24	SEC24A SEC24B	1.38e-03	6	182	2	PF04810
Domain	Sec23_trunk	SEC24A SEC24B	1.38e-03	6	182	2	PF04811
Domain	Sec23_helical	SEC24A SEC24B	1.38e-03	6	182	2	PF04815
Domain	Sec23_BS	SEC24A SEC24B	1.38e-03	6	182	2	PF08033
Domain	Sec23/24_trunk_dom	SEC24A SEC24B	1.38e-03	6	182	2	IPR006896
Domain	Znf_Sec23_Sec24	SEC24A SEC24B	1.38e-03	6	182	2	IPR006895
Domain	ConA-like_dom	TRIM51 ITGB4 RYR2 RYR3 NRXN3 COL14A1 ADGRD2 TRIM47	1.41e-03	219	182	8	IPR013320
Domain	ProC_N	PYCR1 PYCR2	1.92e-03	7	182	2	IPR028939
Domain	Recep_L_domain	INSRR IGF1R	1.92e-03	7	182	2	PF01030
Domain	Furin-like	INSRR IGF1R	1.92e-03	7	182	2	PF00757
Domain	Rcpt_L-dom	INSRR IGF1R	1.92e-03	7	182	2	IPR000494
Domain	F420_oxidored	PYCR1 PYCR2	1.92e-03	7	182	2	PF03807
Domain	Furin-like_Cys-rich_dom	INSRR IGF1R	1.92e-03	7	182	2	IPR006211
Domain	-	INSRR IGF1R	1.92e-03	7	182	2	3.80.20.20
Domain	DHC_N1	DNAH5 DNAH8	2.54e-03	8	182	2	PF08385
Domain	Dynein_heavy_dom-1	DNAH5 DNAH8	2.54e-03	8	182	2	IPR013594
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SETD1A TRPM4 STK36 RTTN NUP214 ZZEF1 ITGB4 NR2F2 RGS16 ITPR2 FANCA IGF1R BRD2 ZBED4 FAM83F SETD5 PIK3CD FANCI TLN1 KBTBD11 PIGW ZFYVE26 GCN1 PREX1 BAHCC1	1.08e-09	1105	184	25	35748872
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	GAPVD1 HSPA4L USP9X PSMA1 PSMB6 SPTLC1 NUP214 DNAJC7 RRP1 SACM1L FANCA CNNM4 PPP2R1A STX18 FANCI TLN1 SEC24B LSS NUP93 GCN1 VARS1 STOM	6.65e-09	942	184	22	31073040
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	GAPVD1 ATG7 HSPA4L USP9X PSMA1 SPTLC1 NCBP1 CHD4 RPS28 RRM1 PRPF8 DNAJC7 SACM1L PPP2R1A AP2A2 FANCI TLN1 NUP93 PYCR2 GCN1 VARS1	9.98e-09	878	184	21	37223481
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	GAPVD1 HSPA4L USP9X NCBP1 CHD4 NUP214 RRM1 PRPF8 DNAJC7 PPP2R1A CTR9 FANCI TLN1 PYCR1 NUP93 PYCR2 GCN1 VARS1	1.00e-08	638	184	18	33239621
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	MYH1 HSPA4L CNTRL EML6 ANKRD26 NCBP1 CHD4 LRRC43 PRPF8 DNAJC7 CXXC1 RYR2 NRXN3 BRD2 ZBED4 AP2A2 SETD5 CTR9 PYCR1 MACF1 SPDEF METTL25 PYCR2 DNAH8 PREX1 VARS1 BAHCC1	1.24e-08	1442	184	27	35575683
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SETD1A GAPVD1 HSPA4L MED16 USP9X NVL CHD4 NUP214 ITPR2 CTR9 DDX54 NUP93 USP54 MED17 NXF1	1.53e-08	440	184	15	34244565
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	USP9X PSMA1 PSMB6 SRP19 NCBP1 CHD4 RPS28 PRPF8 DNAJC7 ZZEF1 PPP2R1A GK STX18 FANCI IPO13 NUP93 GCN1 STOM	1.57e-08	657	184	18	36180527
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	GAPVD1 USP9X PSMA1 PSMB6 CHD4 NUP214 RPS28 DNAJC7 POLR3C FANCI PYCR1 NUP93 PYCR2 GCN1 VARS1 NXF1	3.02e-08	534	184	16	35032548
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	HSPA4L PSMA1 PSMB6 SPTLC1 ZNF622 NCBP1 CHD4 RRM1 PRPF8 DNAJC7 RRP1 SACM1L ITPR2 CNNM4 PPP2R1A STX18 AP2A2 FANCI TLN1 DDX54 IPO13 PYCR1 DHX32 NUP93 PYCR2 GCN1	4.88e-08	1440	184	26	30833792
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	GAPVD1 HSPA4L PSMA1 PSMB6 ZNF622 NCBP1 CHD4 NUP214 RPS28 PRPF8 DNAJC7 RRP1 SACM1L DNAH1 PPP2R1A IGF1R AP2A2 TLN1 SEC24B DDX54 NUP93 MED17 GCN1 VARS1	5.21e-08	1247	184	24	27684187
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	RELCH GAPVD1 ATG7 HSPA4L USP9X ACO1 PSMA1 SEC24A PSMB6 ZNF622 SRP19 NCBP1 RPS28 RRM1 DNAJC7 ZZEF1 PPP2R1A OSBP ASB6 CTR9 FANCI TLN1 MACF1 TRIM47 GCN1 VARS1	5.99e-08	1455	184	26	22863883
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ZSWIM8 GAPVD1 USP9X NVL NCBP1 CHD4 NUP214 PRPF8 RRP1 PPP2R1A FANCI TLN1 DDX54 MACF1 NUP93 GCN1 NXF1	8.33e-08	653	184	17	22586326
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	HSPA4L USP9X RYR2 BRD2 AP2A2 TLN1 SEC24B MACF1 PYCR2 TRIM47	1.10e-07	197	184	10	20811636
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	GAPVD1 HSPA4L USP9X PSMA1 SPTLC1 NCBP1 CHD4 NUP214 PRPF8 DNAJC7 RRP1 SACM1L PPP2R1A AP2A2 CTR9 FANCI TLN1 DDX54 PYCR1 NUP93 PYCR2 DNAH5 GCN1 VARS1 NXF1	1.56e-07	1425	184	25	30948266
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RELCH USP9X SEC24A DUSP8 NCBP1 DNAJC7 ITPR2 PHKA1 CNNM4 PPP2R1A BRD2 PTPRG PTPRN2 CTR9 FANCI SEC24B DDX54 PYCR1 NUP93 PYCR2 GCN1	2.00e-07	1049	184	21	27880917
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	KLHL6 USP9X EML6 CHD4 PRPF8 NR2F2 ZBED4 SETD5 TLN1 MACF1 FGL1 DNAH5	2.37e-07	332	184	12	37433992
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	USP9X PSMA1 PSMB6 RPS28 PRPF8 DNAJC7 PPP2R1A STX18 FANCI CEP250 NUP93 GCN1 STOM	3.11e-07	408	184	13	33766124
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	TANK HSPA4L CNTRL SPTLC1 NUP214 DNAJC7 ITPR2 FANCI CEP250 GCN1 NXF1	3.99e-07	285	184	11	32838362
Pubmed	Proteomic analysis of α4β1 integrin adhesion complexes reveals α-subunit-dependent protein recruitment.	PSMA1 PSMB6 CHD4 NUP214 RPS28 PRPF8 DNAJC7 PPP2R1A TLN1 PYCR1 NUP93 GCN1 VARS1 STOM	4.12e-07	491	184	14	22623428
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	GAPVD1 HSPA4L USP9X BEND4 NUP214 RPS28 MEI1 SMC5 PRPF8 DNAJC7 RYR3 PPP2R1A IGF1R DDX54	4.76e-07	497	184	14	36774506
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	HSPA4L USP9X PSMA1 SEC24A PSMB6 ZNF622 SRP19 NCBP1 CHD4 RPS28 RRM1 PRPF8 DNAJC7 PPP2R1A AP2A2 CTR9 TLN1 DDX54 PYCR1 MACF1 TRIM47 GCN1 VARS1 SPINK5	5.19e-07	1415	184	24	28515276
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	STK36 CNTRL PSMB6 SPTLC1 ZNF622 CHD4 NUP214 PRPF8 DNAJC7 SEC24B IRAG2 PYCR1 KDM8 NUP93 TRIM47 NXF1 MAP3K19	6.22e-07	754	184	17	35906200
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	ZSWIM8 ATG7 HSPA4L USP9X PSMA1 PSMB6 SPTLC1 MRPL10 SRP19 NCBP1 CHD4 RPS28 PRPF8 DNAJC7 RRP1 PPP2R1A AP2A2 PYCR1 DHX32 NUP93 PYCR2 MED17 NXF1	7.01e-07	1335	184	23	29229926
Pubmed	SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.	GAPVD1 USP9X NCBP1 PRPF8 SACM1L AP2A2 TLN1 SEC24B PYCR1 NUP93 PYCR2 GCN1 VARS1 NXF1 STOM	9.51e-07	607	184	15	39147351
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	HSPA4L SPTLC1 MRPL10 NVL ANKRD26 ZNF622 RPS28 RRM1 PRPF8 DNAJC7 RRP1 ITPR2 BRD2 STX18 CTR9 TLN1 DDX54 PYCR1 MACF1 COL14A1 LSS PYCR2 STOM EPHA7	1.24e-06	1487	184	24	33957083
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	GAPVD1 WWOX HSPA4L USP9X SEC24A ANKRD26 NUP214 RRM1 DNAJC7 PPP2R1A FANCI TLN1 SEC24B MACF1 MED17 GCN1	1.31e-06	708	184	16	39231216
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	GAPVD1 USP9X CHD4 NUP214 RRM1 PRPF8 PPP2R1A CTR9 TLN1 GCN1 VARS1	1.77e-06	332	184	11	32786267
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	ATG7 MED16 PSMA1 PSMB6 NVL NCBP1 CHD4 SMC5 PRPF8 DNAJC7 NR2F2 POLR3C PPP2R1A BRD2 CTR9 FANCI NUP93 MED17 NXF1	2.09e-06	1014	184	19	32416067
Pubmed	Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.	RYR2 RYR3 ITPR2	2.88e-06	6	184	3	23463619
Pubmed	Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.	RYR2 RYR3 ITPR2	2.88e-06	6	184	3	25966694
Pubmed	A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.	RYR2 RYR3 ITPR2	2.88e-06	6	184	3	20519450
Pubmed	IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.	RYR2 RYR3 ITPR2	2.88e-06	6	184	3	16844763
Pubmed	IKK-Mediated Regulation of the COP9 Signalosome via Phosphorylation of CSN5.	GAPVD1 HSPA4L PSMA1 PSMB6 NCBP1 SACM1L OSBP ASB6 STOM	3.00e-06	221	184	9	31950832
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	SETD1A PSMA1 PSMB6 CHD4 NUP214 RRM1 PRPF8 CXXC1 PPP2R1A AP2A2 CTR9 FANCI TLN1 SEC24B DDX54 PYCR1 MACF1 NUP93 PYCR2 GCN1 VARS1 NXF1	3.18e-06	1353	184	22	29467282
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	HSPA4L USP9X PSMA1 PSMB6 SRP19 CHD4 RPS28 PRPF8 DNAJC7 PHKA1 PPP2R1A AP2A2 FANCI TLN1 PYCR1 MACF1 NUP93 PYCR2 GCN1 VARS1	3.37e-06	1149	184	20	35446349
Pubmed	The HIV-1 Tat protein recruits a ubiquitin ligase to reorganize the 7SK snRNP for transcriptional activation.	HSPA4L USP9X PSMA1 PSMB6 MRPL10 SRP19 NCBP1 CHD4 RPS28 RRM1 PRPF8 DNAJC7 RRP1 PPP2R1A AP2A2 CTR9 OSBPL1A MACF1 HES1 VARS1	3.55e-06	1153	184	20	29845934
Pubmed	Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.	DNAH1 DNAH5 DNAH8	5.02e-06	7	184	3	9256245
Pubmed	Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.	RYR2 RYR3 ITPR2	5.02e-06	7	184	3	11860456
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	KLHL6 MYH1 GAPVD1 TANK HSPA4L MED16 CHD4 ITPR2 ANKRD36B PHKA1 PPP2R1A IGF1R BRD2 AP2A2 CTR9 TLN1 EPHA7	7.68e-06	910	184	17	36736316
Pubmed	A protein interaction landscape of breast cancer.	GAPVD1 HSPA4L USP9X ACO1 SRP19 DNAJC7 AP2A2 FANCI TLN1 DDX54 PYCR1 MACF1 LSS STOM	8.00e-06	634	184	14	34591612
Pubmed	Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.	RYR2 RYR3 ITPR2	8.00e-06	8	184	3	19033399
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	KLHL6 WWOX USP9X SPTLC1 ZNF622 ZDBF2 NUP214 SMC5 PREX2 SACM1L RTKN2 BRD2 ZBED4 PTPRN2 CENPM CTR9 DDX54 KICS2 LSS GCN1 NXF1	8.17e-06	1327	184	21	32694731
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	HSPA4L PSMA1 PSMB6 SPTLC1 MRPL10 NUP214 PREX2 PPP2R1A AP2A2 FANCI TLN1 PYCR1 NUP93 PYCR2 GCN1 PREX1 STOM	8.36e-06	916	184	17	32203420
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SETD1A NCBP1 CHD4 CXXC1 RRP1 BRD2 CTR9 DDX54 PYCR1	8.40e-06	251	184	9	31076518
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	GAPVD1 USP9X NCBP1 CHD4 NUP214 PRPF8 DNAJC7 RRP1 ITPR2 PPP2R1A BRD2 TLN1 DDX54 MACF1 NUP93 GCN1 VARS1 NXF1	9.38e-06	1024	184	18	24711643
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MYH1 GAPVD1 ZNF622 NCBP1 PRPF8 ZZEF1 CXXC1 ITPR2 FANCA ZBED4 PTPRN2 TLN1 PIGW KDM8 NXF1	9.77e-06	736	184	15	29676528
Pubmed	Interactome of the Autoimmune Risk Protein ANKRD55.	USP9X PRPF8 PPP2R1A FANCI TLN1 GCN1 VARS1 NXF1	1.10e-05	197	184	8	31620119
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	USP9X NCBP1 RRM1 PRPF8 RBM23 SACM1L POLR3C OSBP AP2A2 CTR9 TLN1 DDX54 PYCR2 GCN1	1.11e-05	653	184	14	33742100
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	MED16 NVL ZNF622 NCBP1 CHD4 RPS28 SMC5 PRPF8 NR2F2 RRP1 DDX54 MACF1 MED17 GCN1 NXF1	1.40e-05	759	184	15	35915203
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	TANK PSMA1 RTTN PSMB6 CXXC1 DNAH1 FANCA AP2A2 PTPRN2 CENPM DDX54 MACF1	1.48e-05	496	184	12	31343991
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	GAPVD1 HSPA4L PSMA1 NUP214 PRPF8 TBCCD1 CNNM4 PPP2R1A PTPRN2 CTR9 FANCI DDX54 PYCR1 NUP93 PYCR2 GCN1 VARS1	1.84e-05	974	184	17	28675297
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	HSPA4L PSMA1 PSMB6 SPTLC1 MRPL10 NUP214 DNAJC7 SACM1L FANCI DDX54 PYCR1 DHX32 USP54	2.29e-05	606	184	13	36538041
Pubmed	Primary Ciliary Dyskinesia	ODAD2 DNAH1 DNAH5 DNAH8	2.43e-05	32	184	4	20301301
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	MED16 PSMA1 NCBP1 RPS28 RRP1 ITPR2 PPP2R1A TLN1 DDX54 PYCR1 NUP93 MED17 GCN1 NXF1	2.43e-05	701	184	14	30196744
Pubmed	K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains.	HSPA4L USP9X PSMA1 NCBP1 PPP2R1A	2.51e-05	65	184	5	29378950
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	PSMB6 NCBP1 CHD4 RPS28 PRPF8 PPP2R1A AP2A2 TLN1 MACF1 NUP93 PYCR2 GCN1 VARS1 STOM	2.67e-05	707	184	14	19738201
Pubmed	Frmpd1 Facilitates Trafficking of G-Protein Transducin and Modulates Synaptic Function in Rod Photoreceptors of Mammalian Retina.	FRMPD1 GPSM2	2.78e-05	2	184	2	36180221
Pubmed	Structural and biochemical characterization of the interaction between LGN and Frmpd1.	FRMPD1 GPSM2	2.78e-05	2	184	2	23318951
Pubmed	Coexpression of insulin receptor-related receptor and insulin-like growth factor 1 receptor correlates with enhanced apoptosis and dedifferentiation in human neuroblastomas.	INSRR IGF1R	2.78e-05	2	184	2	14654552
Pubmed	Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase.	PREX2 PREX1	2.78e-05	2	184	2	20694145
Pubmed	IGF1R stimulates autophagy, enhances viability, and promotes insulin secretion in pancreatic β cells in gestational diabetes mellitus by upregulating ATG7.	ATG7 IGF1R	2.78e-05	2	184	2	38262267
Pubmed	NuRD complex component Mi-2beta binds to and represses RORgamma-mediated transcriptional activation.	CHD4 RORC	2.78e-05	2	184	2	15144897
Pubmed	Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.	RYR2 RYR3	2.78e-05	2	184	2	8898078
Pubmed	The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.	RYR2 RYR3	2.78e-05	2	184	2	14550562
Pubmed	Mitochondrial calcium overload is a key determinant in heart failure.	RYR2 ITPR2	2.78e-05	2	184	2	26217001
Pubmed	Targeting Ribonucleotide Reductase Induces Synthetic Lethality in PP2A-Deficient Uterine Serous Carcinoma.	RRM1 PPP2R1A	2.78e-05	2	184	2	34921012
Pubmed	P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.	PREX2 PREX1	2.78e-05	2	184	2	18334636
Pubmed	Combined exome and whole-genome sequencing identifies mutations in ARMC4 as a cause of primary ciliary dyskinesia with defects in the outer dynein arm.	ODAD2 DNAH5	2.78e-05	2	184	2	24203976
Pubmed	P-Rex1 and P-Rex2 RacGEFs and cancer.	PREX2 PREX1	2.78e-05	2	184	2	28710285
Pubmed	Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.	RYR2 RYR3	2.78e-05	2	184	2	21531043
Pubmed	Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.	RYR2 RYR3	2.78e-05	2	184	2	16678258
Pubmed	CXXC finger protein 1 restricts the Setd1A histone H3K4 methyltransferase complex to euchromatin.	SETD1A CXXC1	2.78e-05	2	184	2	19951360
Pubmed	Functional local crosstalk of inositol 1,4,5-trisphosphate receptor- and ryanodine receptor-dependent Ca2+ release in atrial cardiomyocytes.	RYR2 ITPR2	2.78e-05	2	184	2	28158491
Pubmed	Oxysterol-binding protein recruitment and activity at the endoplasmic reticulum-Golgi interface are independent of Sac1.	SACM1L OSBP	2.78e-05	2	184	2	28471037
Pubmed	Molecular and biochemical characterization of a novel oxysterol-binding protein (OSBP2) highly expressed in retina.	OSBP OSBP2	2.78e-05	2	184	2	11278871
Pubmed	Decreased expression of ryanodine receptors alters calcium-induced calcium release mechanism in mdx duodenal myocytes.	RYR2 RYR3	2.78e-05	2	184	2	14985349
Pubmed	Terminal deoxynucleotidyl transferase and CD84 identify human multi-potent lymphoid progenitors.	CD84 DNTT	2.78e-05	2	184	2	39003273
Pubmed	Heterogeneity in Fanconi anemia: evidence for 2 new genetic subtypes.	FANCA FANCI	2.78e-05	2	184	2	14630800
Pubmed	Phosphorylation of P-Rex1 at serine 1169 participates in IGF-1R signaling in breast cancer cells.	IGF1R PREX1	2.78e-05	2	184	2	23899556
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	ACO1 CNTRL PSMB6 NCBP1 CHD4 PRPF8 ZZEF1 DNAH1 RTKN2 PPP2R1A AP2A2 TLN1 MACF1 GCN1 STOM	2.84e-05	807	184	15	30575818
Pubmed	Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b.	SEC24A TSPAN2 SEC24B	3.09e-05	12	184	3	20215345
Pubmed	A family of 12 human genes containing oxysterol-binding domains.	OSBP OSBPL1A OSBP2	3.09e-05	12	184	3	11735225
Pubmed	An oxysterol-binding protein family identified in the mouse.	OSBP OSBPL1A OSBP2	3.09e-05	12	184	3	12215260
Pubmed	Genetic interaction mapping in mammalian cells using CRISPR interference.	SETD1A CHD4 CXXC1 CTR9 MED17	3.35e-05	69	184	5	28481362
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	SETD1A TANK USP9X SPTLC1 NCBP1 PRPF8 STX18 ZBED4 SEC24B OSBPL1A PIGW PYCR1 HES1 DHX32 NUP93 PYCR2	3.50e-05	922	184	16	27609421
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	USP9X MRPL10 ZDBF2 RYR2 ANKRD36B OSBP PTPRN2 NXF5 PYCR1 CTNND2 PYCR2 MED17 PREX1	3.90e-05	638	184	13	31182584
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	WWOX USP9X ACO1 PSMA1 PSMB6 NCBP1 CHD4 NUP214 RRM1 PRPF8 DNAJC7 RRP1 SACM1L PPP2R1A TLN1 PYCR1 NUP93 GCN1 VARS1 NXF1	4.12e-05	1367	184	20	32687490
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	HSPA4L USP9X PSMA1 PSMB6 SPTLC1 NCBP1 RPS28 RRM1 PRPF8 DNAJC7 PPP2R1A CTR9 FANCI PYCR1 NUP93 MED17 GCN1 VARS1 NXF1	4.20e-05	1257	184	19	37317656
Pubmed	The TIP60 Complex Is a Conserved Coactivator of HIF1A.	SPTLC1 PRPF8 PPP2R1A FANCI NUP93 GCN1	4.48e-05	120	184	6	27320910
Pubmed	Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.	MYH1 USP9X PSMB6 RPS28 PRPF8 DNAJC7 PPP2R1A AP2A2 TLN1 SEC24B MACF1 DHX32 CTNND2 GCN1 SMTNL2	4.73e-05	844	184	15	25963833
Pubmed	Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.	RYR2 RYR3 ITPR2 CACNA1I	4.86e-05	38	184	4	30786075
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DNAH1 DNAH5 DNAH8	5.08e-05	14	184	3	9373155
Pubmed	TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.	NUP214 NXF5 NXF1	5.08e-05	14	184	3	11073998
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	ZSWIM8 USP9X ACO1 SPTB NCBP1 CHD4 PRPF8 DNAJC7 RYR3 BRD2 STX18 CTR9 OSBPL1A GPSM2 MACF1 USP54 CTNND2 PREX1 VARS1	5.63e-05	1285	184	19	35914814
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	USP9X SPTLC1 PPP2R1A AP2A2 IPO13 NUP93 GCN1	5.74e-05	183	184	7	23956138
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	RELCH USP9X PSMB6 SPTLC1 CHD4 DNAJC7 PPP2R1A TLN1 GCN1 VARS1	5.76e-05	399	184	10	37536630
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	GAPVD1 USP9X NVL CHD4 PRPF8 PPP2R1A BRD2 AP2A2 CTR9 NUP93 PYCR2 VARS1 STOM	5.93e-05	665	184	13	30457570
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	HSPA4L USP9X ANKRD26 ZNF622 NCBP1 DNAJC7 RRP1 ITIH5 BTBD16 RTKN2 PYCR1 NUP93 PYCR2	6.40e-05	670	184	13	22990118
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	KLHL6 GAPVD1 WWOX CNTRL FRMPD1 PSMB6 MRPL10 CLDND1 ITGB4 TBCCD1 SETD5 PIK3CD CTR9 SOCS5 PIGW MACF1 LPAR2	6.94e-05	1084	184	17	11544199
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	RBM45 SRP19 NCBP1 CHD4 PRPF8 PPP2R1A BRD2 FANCI TLN1 MACF1 NUP93 GCN1	6.94e-05	582	184	12	20467437
Cytoband	9q34.1	NCBP1 NUP214 STOM	5.85e-05	19	184	3	9q34.1
Cytoband	11q12-q13	OSBP NXF1	2.37e-04	6	184	2	11q12-q13
GeneFamily	Oxysterol binding proteins\|Pleckstrin homology domain containing	OSBP OSBPL1A OSBP2	7.11e-05	12	127	3	670
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR2 RYR3	1.46e-04	3	127	2	287
GeneFamily	Dyneins, axonemal	DNAH1 DNAH5 DNAH8	2.14e-04	17	127	3	536
GeneFamily	Fibronectin type III domain containing	INSRR ITGB4 IGF1R PTPRG COL14A1 EPHA7	9.37e-04	160	127	6	555
Coexpression	GSE22886_NAIVE_CD4_TCELL_VS_12H_ACT_TH2_DN	TANK PSMA1 SRP19 CLDND1 NCBP1 RRM1 RBM23 SACM1L FANCI NUP93	1.62e-06	200	184	10	M4527
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 STK36 MYO7B ODAD2 TEX11 RYR2 RYR3 DNAH1 DNAH5 EPHA7	5.29e-09	184	184	10	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 STK36 MYO7B ODAD2 TEX11 RYR2 RYR3 DNAH1 DNAH5 EPHA7	5.29e-09	184	184	10	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYH1 STK36 MYO7B ODAD2 TEX11 RYR2 RYR3 DNAH1 DNAH5 EPHA7	5.29e-09	184	184	10	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GAPVD1 CHD4 KMT2E PREX2 RRP1 ITIH5 TLN1 MACF1	1.29e-06	190	184	8	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1\|TCGA-Endometrium / Sample_Type by Project: Shred V9	NCBP1 RRM1 PANK1 FANCA ZBED4 FANCI GPSM2 EPHA7	1.45e-06	193	184	8	c2673d86f7d7b849788036032a93a6d136a70040
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL6 RPS28 DNAJC7 DDX54 IRAG2 HES1 RBM24 SMTNL2	1.51e-06	194	184	8	7ee8ac172c2dee7df7dc4eb222e0985a0089bda8
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KLHL6 SEC24A EML6 MEI1 IRAG2 DNAH8 MAP3K19 SEC14L1	1.63e-06	196	184	8	fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A2 ST8SIA1 NR2F2 ITIH5 PXDNL GPSM2 MACF1 COL14A1	1.90e-06	200	184	8	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	Control-Endothelial-Epi-like-Alv_Cap\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ACO1 ASTE1 LGSN WDR91 PTPRN2 CEP250 KDM8	4.15e-06	157	184	7	2c369660c752c0fb3bd798a561d3359e2f9aa983
ToppCell	Control-Endothelial-Epi-like\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ACO1 ASTE1 LGSN WDR91 PTPRN2 CEP250 KDM8	4.15e-06	157	184	7	4d02c50d5d1b892ea241e98724386d8a5a156a46
ToppCell	normal_Pleural_Fluid-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	COL6A2 DUSP8 RAET1E RTKN2 FRRS1 ZSCAN22 KDM8	5.99e-06	166	184	7	d16af6570806ed2880bd0efb5298932fd2a89cf5
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM4 ZSWIM8 HSPA4L BEND4 TSPAN2 BTBD16 CNTD1	6.47e-06	168	184	7	de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTLC1 RYR2 RYR3 DNAH1 NRXN3 DNAH5 SPINK5	6.73e-06	169	184	7	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	droplet-Lung-nan-18m-Myeloid-Plasmacytoid_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRF1 CNTRL INSRR ST8SIA1 DNAJC7 CTNND2 DNTT	7.00e-06	170	184	7	749144a1a869a6bf9acdd227184319083367dc3f
ToppCell	droplet-Lung-nan-18m-Myeloid-plasmacytoid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RASGRF1 CNTRL INSRR ST8SIA1 DNAJC7 CTNND2 DNTT	7.00e-06	170	184	7	25d60a62e8f99c31ab64fe6a0c07ccca3df1a7ee
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRF1 CNTRL INSRR ST8SIA1 DNAJC7 CTNND2 DNTT	7.55e-06	172	184	7	1abb6fbb28c8aff384540493d0f70eeacaa751f4
ToppCell	droplet-Lung-18m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRF1 CNTRL INSRR ST8SIA1 DNAJC7 CTNND2 DNTT	7.55e-06	172	184	7	422d311bba2dd5d8bece4e96ee8c86e78086b62d
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-B_cells-Memory_B\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLHL6 RASGRF1 EML6 CD84 PIK3CD IRAG2 PREX1	9.10e-06	177	184	7	0d1c39e99144fdb9c7f6f98a1ade41c73db45b65
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	WWOX BEND4 RRM1 GK GPSM2 ZFYVE26 GCN1	9.10e-06	177	184	7	1d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	SETD1A TANK SEC24A ANKRD26 NCBP1 ITIH5 GK	1.30e-05	187	184	7	c8278525b3e1d3f3f4defcaf109cce22dd2e157a
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST8SIA1 NR2F2 DNAH1 ITPR2 FRRS1 TRIM47 EPHA7	1.39e-05	189	184	7	8e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	RTTN RRM1 TSPAN2 FANCA RTKN2 CENPM FANCI	1.44e-05	190	184	7	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	droplet-Heart-HEART-1m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRMPD1 ITGB4 NR2F2 FRRS1 LRRC42 NRXN3 SMTNL2	1.49e-05	191	184	7	4bfdf44d4402a42530d30c89d94946acdda4321b
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 ST8SIA1 NR2F2 RYR2 PXDNL GPSM2 COL14A1	1.54e-05	192	184	7	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 ST8SIA1 RGS16 RYR2 PXDNL GPSM2 COL14A1	1.54e-05	192	184	7	f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGB4 PREX2 RYR3 CTNND2 PREX1 STOM SEC14L1	1.60e-05	193	184	7	2e72309607902dabe3218888b22a77fe941f3570
ToppCell	droplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL6 CNTRL DNAJC7 IRAG2 HES1 SMTNL2 DNTT	1.65e-05	194	184	7	8ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLDND1 ST8SIA1 RPS28 CD84 RTKN2 RORC TRIM47	1.76e-05	196	184	7	3a08209210e1a8677097a78786e00062c81b1ad2
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm-\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	CLDND1 ST8SIA1 RPS28 CD84 RTKN2 RORC TRIM47	1.76e-05	196	184	7	d4fd5513e98eec092d51199e7f054bc15a5eaa3d
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLDND1 ST8SIA1 RPS28 CD84 RTKN2 RORC TRIM47	1.76e-05	196	184	7	fddc3e89e7e6b093563655c2d02e86836cfd6da5
ToppCell	COVID-19_Convalescent-CD4+_Tcm\|COVID-19_Convalescent / Disease condition and Cell class	CLDND1 ST8SIA1 RPS28 CD84 RTKN2 RORC TRIM47	1.76e-05	196	184	7	f2a5eeb1cebde2762865ab29792370b751214c4d
ToppCell	COVID-19_Convalescent-Lymphoid_T/NK-CD4+_Tcm\|COVID-19_Convalescent / Disease group, lineage and cell class	CLDND1 ST8SIA1 RPS28 CD84 RTKN2 RORC TRIM47	1.76e-05	196	184	7	8caf4334ae692ce44e8fea5d606416afc5b72c00
ToppCell	remission-CD4+_Tcm\|remission / disease stage, cell group and cell class	CLDND1 ST8SIA1 RPS28 CD84 RTKN2 RORC TRIM47	1.76e-05	196	184	7	db7a9669ae35e2c6b465941afef9f7a6b1e7190e
ToppCell	PBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_Tcm\|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)	CLDND1 ST8SIA1 RPS28 CD84 RTKN2 RORC TRIM47	1.76e-05	196	184	7	7d841113a7161b017a08602d46366ac044271b34
ToppCell	LPS_only-Epithelial_airway-airway_epithelial-Ciliated\|LPS_only / Treatment groups by lineage, cell group, cell type	STK36 ODAD2 LRRC43 DNAH1 FRRS1 LSS DNAH5	1.88e-05	198	184	7	6d90b541fde357fbb40f8f7d4e8628a48b679718
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A2 NR2F2 ITIH5 PXDNL GPSM2 MACF1 COL14A1	1.94e-05	199	184	7	c2c42ecf20d1924edc2f899c01dfa5fcf3c210b9
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A2 NR2F2 RYR2 PXDNL GPSM2 MACF1 COL14A1	1.94e-05	199	184	7	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL6A2 PREX2 NR2F2 ITIH5 PXDNL MACF1 COL14A1	1.94e-05	199	184	7	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A2 NR2F2 ITIH5 PXDNL GPSM2 MACF1 COL14A1	2.01e-05	200	184	7	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	COL6A2 RYR2 ITIH5 PXDNL GPSM2 MACF1 COL14A1	2.01e-05	200	184	7	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	LPS_IL1RA_TNF-Epithelial_airway\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ODAD2 SLC9C2 DNAH1 DNAH5 MSLN MAP3K19 SPINK5	2.01e-05	200	184	7	72c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCell	Transverse-Dendritic_cell-cycling_DCs\|Dendritic_cell / Region, Cell class and subclass	NUP214 RRM1 CENPM FANCI OSBPL1A GPSM2 HES1	2.01e-05	200	184	7	617a6a42f7b31eb3c45bdceaf55a591b6de7f154
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ODAD2 SLC9C2 DNAH1 DNAH5 MSLN MAP3K19 SPINK5	2.01e-05	200	184	7	da12821e8a0657869ca0f75d351cce2d7605a505
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL6A2 PREX2 NR2F2 PXDNL GPSM2 MACF1 COL14A1	2.01e-05	200	184	7	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	COVID-19-COVID-19_Convalescent-Lymphocyte-T/NK-CD4+_Tcm\|COVID-19_Convalescent / Disease, condition lineage and cell class	CLDND1 ST8SIA1 RPS28 CD84 RTKN2 RORC TRIM47	2.01e-05	200	184	7	99c5abfe96d791c60ae6021ab4201851ee4afc47
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A2 NR2F2 ITIH5 PXDNL GPSM2 MACF1 COL14A1	2.01e-05	200	184	7	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL6A2 PREX2 NR2F2 PXDNL GPSM2 MACF1 COL14A1	2.01e-05	200	184	7	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	facs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYH1 BEND4 ZBTB12 RYR2 CENPM SPDEF	3.51e-05	148	184	6	5983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCell	Substantia_nigra-Macroglia-POLYDENDROCYTE\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CLDND1 TSPAN2 ITPR2 BTBD16 GPSM2 PREX1	3.79e-05	150	184	6	70ac8ae4b1683fb17278a8e4606f2fa0b94988c0
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LHX4 SLC9C2 CNTD1 NRXN3 MAP3K19	5.41e-05	98	184	5	ffe21b3681fdeaf4a8447bd2b13772d03cdd45aa
ToppCell	human_hepatoblastoma-Tumor_cells-T0\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	WWOX MEI1 ITPR2 RNASE2 CTNND2	5.68e-05	99	184	5	eeb2d10170154c61717c38f85d0fbb61c4c48bb3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RRM1 FANCA RTKN2 CENPM FANCI MED17	6.44e-05	165	184	6	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like-ILC3\|GI_small-bowel / Manually curated celltypes from each tissue	TSPAN2 IGF1R KBTBD11 RORC RBM24 BAHCC1	6.65e-05	166	184	6	773673a5d0430640439845b264740bfbbdad0cb2
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_Invariant-Inducer-like\|GI_small-bowel / Manually curated celltypes from each tissue	TSPAN2 IGF1R KBTBD11 RORC RBM24 BAHCC1	6.88e-05	167	184	6	3ae46c6363da76c8e1f5579e6027bf88ed637a44
ToppCell	Tuft-tuft-1\|World / Class top	RTTN EML6 SOCS5 IRAG2 PYCR1 SPDEF	7.11e-05	168	184	6	8ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL6A2 NR2F2 RYR2 ITIH5 COL14A1 FGL1	7.84e-05	171	184	6	a4a2c5dc995589fbe3d4ca6ee1df888807e4ae34
ToppCell	droplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRF1 ST8SIA1 ZBED4 ACOT11 PYCR1 DNTT	7.84e-05	171	184	6	2dfed6e9ac89adb2501a1a5e1ca895f49190562d
ToppCell	droplet-Lung-21m-Hematologic-myeloid-plasmacytoid_dendritic_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	RASGRF1 ST8SIA1 ZBED4 ACOT11 PYCR1 DNTT	7.84e-05	171	184	6	2aaae0229c3a13d0275a03a3d576db650c2bf2c0
ToppCell	droplet-Thymus-nan-24m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHMP1B ZSCAN22 CTR9 RORC RBM24 DNTT	7.84e-05	171	184	6	d1e87478d8c0329e662849823f5c7604f20e1b1a
ToppCell	mild_COVID-19_(asymptomatic)-RBC\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	WWOX ZDBF2 RGS16 CENPM SOCS5 KICS2	7.84e-05	171	184	6	78491478ba65bad45238fe114f5251b2adea323d
ToppCell	Immune_cells-pro-B\|Immune_cells / Lineage and Cell class	KLHL6 RPS28 IRAG2 HES1 SMTNL2 DNTT	8.10e-05	172	184	6	096636f2589fa56d15942aac96641c16fd5fa78d
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	COL6A2 SPTB NR2F2 TSPAN2 RYR2 COL14A1	8.10e-05	172	184	6	c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCell	E18.5-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ITIH5 CNTD1 ZSCAN22 KBTBD11 HES1 SPINK5	8.10e-05	172	184	6	1bbf5ed7d13635f9a7e528060341e0652699bd7c
ToppCell	3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	STK36 ODAD2 LRRC43 CENPM DNAH5 MAP3K19	8.36e-05	173	184	6	c3762655caa79ac4879876f470d32578a3c93b01
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FANCA RTKN2 ANKRD33 CENPM FANCI GPSM2	8.63e-05	174	184	6	84da9faff088d05233183b425385beb054c92d1b
ToppCell	droplet-Marrow-nan-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPM4 ACO1 SHLD1 ZZEF1 DNAH1 BAHCC1	8.63e-05	174	184	6	55cc8300489d11322724159ec7d0e1d32a702e91
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-ILCP\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MEI1 PHKA1 FRRS1 IRAG2 RORC PREX1	8.90e-05	175	184	6	f2c3e0f728a43d6988e793c8a50c964f7447db82
ToppCell	facs-GAT-Fat-3m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL6 ST8SIA1 RPS28 TEX11 ITPR2 DNAH8	9.19e-05	176	184	6	acd05ca8952710feedbfe377b1330f3c2406d044
ToppCell	ASK428-Epithelial-Secretory\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	FOLR3 LGSN ITGB4 ITIH5 IRAG2 COL14A1	9.48e-05	177	184	6	66074a288501c136b4e83b883db5f0d8269ee326
ToppCell	3'-Adult-SmallIntestine-Hematopoietic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLHL6 EML6 CD84 PIK3CD IRAG2 PREX1	9.78e-05	178	184	6	da1695a936dbe3ca9ee3fb28ceb60511c47b35f8
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-B_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	KLHL6 EML6 CD84 PIK3CD IRAG2 PREX1	9.78e-05	178	184	6	580fc1d45b82010c665a313b2e7a21e0116819ef
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|356C / Donor, Lineage, Cell class and subclass (all cells)	SETD1A TANK ANKRD26 NCBP1 ITIH5 LPAR2	1.01e-04	179	184	6	f378307eb20f002450c748b7be2289d6db2fcbcb
ToppCell	E16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ZBTB12 WDR91 RTKN2 RORC USP54 MSLN	1.07e-04	181	184	6	f6629fa71bb94405f523f63a9264cacf6d15c5f4
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	KIAA1586 PREX2 ITPR2 PTPRG SOCS5 COL14A1	1.17e-04	184	184	6	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	droplet-Lung-18m-Hematologic-myeloid-classical_monocyte_proliferating-classical_monocyte_proliferating_l33-52\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EML6 RRM1 RTKN2 CNTD1 CENPM FANCI	1.21e-04	185	184	6	47c69500877b851c0c9744f5e1ef2ee0bff99168
ToppCell	COPD-Stromal-Pericyte\|World / Disease state, Lineage and Cell class	COL6A2 RGS16 RYR2 PTPRG HES1 SMTNL2	1.24e-04	186	184	6	8adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCell	COVID-19-kidney-Stressed_PCT\|kidney / Disease (COVID-19 only), tissue and cell type	MYO7B HSPA4L ACO1 PANK1 OSBPL1A EPHA7	1.28e-04	187	184	6	acd305475f3609800af0d7bc68d83ef41228080b
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	ITGB4 PREX2 TSPAN2 PTPRG STOM SEC14L1	1.28e-04	187	184	6	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 ST8SIA1 RGS16 PXDNL GPSM2 COL14A1	1.36e-04	189	184	6	e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ST8SIA1 NR2F2 DNAH1 FRRS1 TRIM47 EPHA7	1.36e-04	189	184	6	fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_3\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	SETD1A SEC24A ANKRD26 NCBP1 ITIH5 GK	1.36e-04	189	184	6	99b01893da9f9f7c9528afaffad178285211738b
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 ST8SIA1 RYR2 PXDNL GPSM2 COL14A1	1.36e-04	189	184	6	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGB4 PREX2 TSPAN2 PREX1 STOM SEC14L1	1.40e-04	190	184	6	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SPTB RYR2 PTPRG PXDNL CTNND2 RBM24	1.40e-04	190	184	6	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	RASGRF1 SPTB ZDBF2 RYR2 NRXN3 PTPRN2	1.40e-04	190	184	6	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 ST8SIA1 NR2F2 RGS16 GPSM2 COL14A1	1.40e-04	190	184	6	d60395739458d7f47a3350ade751fe3819500320
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 ST8SIA1 RYR2 PXDNL GPSM2 COL14A1	1.44e-04	191	184	6	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL6 DNAJC7 DDX54 IRAG2 RBM24 SMTNL2	1.44e-04	191	184	6	318323a12029a7992f16382cb0c186f5b2e1ca47
ToppCell	droplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTB RYR2 RYR3 CILP2 OSBP2 RBM24	1.44e-04	191	184	6	97fb4232417a39801e87725755fd16a57c250209
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL6 DNAJC7 DDX54 IRAG2 RBM24 SMTNL2	1.44e-04	191	184	6	4aa29337f4d2528577bb90dc4abfb6eab93e120f
ToppCell	droplet-Heart-nan-3m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTB RYR2 RYR3 CILP2 OSBP2 RBM24	1.44e-04	191	184	6	64070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCell	Ciliated-cil-3\|World / Class top	STK36 ODAD2 LRRC43 DNAH1 FANCA DNAH5	1.48e-04	192	184	6	4989ebb8812b8af1870599acd932849122c05a29
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_2-D122\|Adult / Lineage, Cell type, age group and donor	RASGRF1 BTBD16 NRXN3 PTPRG LSS DNAH5	1.48e-04	192	184	6	06013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD8+_T-MAIT-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	COL6A2 DUSP8 MRPL10 RGS16 RORC RBM24	1.48e-04	192	184	6	44f440ee3842fe14665c4cd4f2aa48e7a5bbd9a8
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD8+_T-MAIT\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL6A2 DUSP8 MRPL10 RGS16 RORC RBM24	1.48e-04	192	184	6	8d50ad8cfe3cb9f183188b08457756af0ce56ffe
ToppCell	PND14-Mesenchymal-Mesenchymal_structural\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A2 PREX2 NR2F2 GPSM2 MACF1 SMTNL2	1.48e-04	192	184	6	25492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD8+_T-MAIT\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL6A2 DUSP8 MRPL10 RGS16 RORC RBM24	1.48e-04	192	184	6	892789bdba150ef9a8a0012de52545f2ff6a31f6
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A2 PREX2 NR2F2 GPSM2 MACF1 SMTNL2	1.48e-04	192	184	6	de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A2 ST8SIA1 NR2F2 RGS16 RYR2 COL14A1	1.48e-04	192	184	6	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD8+_T-MAIT-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	COL6A2 DUSP8 MRPL10 RGS16 RORC RBM24	1.48e-04	192	184	6	24ea8fdcca2695aeb2e4b88161184124b7d332c1
Disease	eosinophil cationic protein measurement	SPATA31C2 SPATA31C1 RNASE2	1.18e-05	8	178	3	EFO_0010913
Disease	autosomal recessive cutis laxa type IIB (implicated_via_orthology)	PYCR1 PYCR2	3.62e-05	2	178	2	DOID:0070137 (implicated_via_orthology)
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR2 RYR3	1.08e-04	3	178	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR2 RYR3	1.08e-04	3	178	2	DOID:8545 (implicated_via_orthology)
Disease	high grade glioma (implicated_via_orthology)	ATG7 INSRR IGF1R PIK3CD	1.44e-04	44	178	4	DOID:3070 (implicated_via_orthology)
Disease	Primary Ciliary Dyskinesia	STK36 ODAD2 DNAH1 DNAH5	1.86e-04	47	178	4	C4551720
Disease	diabetes mellitus (implicated_via_orthology)	INSRR IGF1R PTPRN2	5.07e-04	26	178	3	DOID:9351 (implicated_via_orthology)
Disease	renal overload-type gout	SPATA31C2 SPATA31C1	5.34e-04	6	178	2	EFO_0021525
Disease	glucose metabolism disease (implicated_via_orthology)	INSRR IGF1R PIK3CD	6.33e-04	28	178	3	DOID:4194 (implicated_via_orthology)
Disease	Abnormality of radial ray	RPS28 FANCA FANCI	1.03e-03	33	178	3	C4228778
Disease	sexual dimorphism measurement	GAPVD1 MRGPRD RASGRF1 SPATA31C2 LRRC43 ZZEF1 SPATA31C1 INTS10 IGF1R NRXN3 PTPRG CEP250 MACF1 SPDEF NUP93 GCN1	1.13e-03	1106	178	16	EFO_0021796
Disease	Kartagener Syndrome	STK36 ODAD2 DNAH1	1.23e-03	35	178	3	C0022521
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	STK36 ODAD2 DNAH1	1.23e-03	35	178	3	C4551906
Disease	Polynesian Bronchiectasis	STK36 ODAD2 DNAH1	1.23e-03	35	178	3	C4317124
Disease	longitudinal alcohol consumption measurement	SPATA31C2 SPATA31C1	1.27e-03	9	178	2	EFO_0007645
Disease	alcohol dependence (implicated_via_orthology)	INSRR IGF1R	1.27e-03	9	178	2	DOID:0050741 (implicated_via_orthology)
Disease	Primary ciliary dyskinesia	ODAD2 DNAH1 DNAH5	1.33e-03	36	178	3	cv:C0008780
Disease	visceral heterotaxy (implicated_via_orthology)	ODAD2 OSBPL1A DNAH5	1.44e-03	37	178	3	DOID:0050545 (implicated_via_orthology)
Disease	cataract (implicated_via_orthology)	IPO13 LSS RBM24	1.56e-03	38	178	3	DOID:83 (implicated_via_orthology)
Disease	interventricular septum thickness	ITPR2 IGF1R	1.58e-03	10	178	2	EFO_0009287
Disease	Fanconi anemia (is_implicated_in)	FANCA FANCI	1.58e-03	10	178	2	DOID:13636 (is_implicated_in)
Disease	Intellectual Disability	SETD1A RTTN KMT2E PPP2R1A NXF5 PYCR1 MACF1 LSS PYCR2	1.65e-03	447	178	9	C3714756
Disease	sleep disorder (implicated_via_orthology)	INSRR IGF1R	1.92e-03	11	178	2	DOID:535 (implicated_via_orthology)
Disease	microphthalmia (implicated_via_orthology)	IPO13 RBM24	2.30e-03	12	178	2	DOID:10629 (implicated_via_orthology)
Disease	esophagus squamous cell carcinoma (is_implicated_in)	WWOX FANCA COL14A1	2.54e-03	45	178	3	DOID:3748 (is_implicated_in)
Disease	egg allergy measurement, parental genotype effect measurement	SPATA31C2 SPATA31C1	2.70e-03	13	178	2	EFO_0005939, EFO_0007018
Disease	Fanconi anemia	FANCA FANCI	3.14e-03	14	178	2	cv:C0015625
Disease	Kartagener syndrome (implicated_via_orthology)	ODAD2 DNAH5	3.14e-03	14	178	2	DOID:0050144 (implicated_via_orthology)
Disease	insulin metabolic clearance rate measurement, glucose homeostasis measurement	ZZEF1 RBM24	3.14e-03	14	178	2	EFO_0006830, EFO_0006896
Disease	diabetic neuropathy (implicated_via_orthology)	INSRR IGF1R	3.14e-03	14	178	2	DOID:9743 (implicated_via_orthology)
Disease	ocular hypertension, response to triamcinolone acetonide	ITGB4 FRRS1 VARS1	3.24e-03	49	178	3	EFO_0006954, EFO_1001069
Disease	myelodysplastic syndrome (implicated_via_orthology)	ATG7 PRPF8	3.61e-03	15	178	2	DOID:0050908 (implicated_via_orthology)
Disease	type 2 diabetes mellitus (implicated_via_orthology)	INSRR NR2F2 IGF1R PIK3CD	3.81e-03	105	178	4	DOID:9352 (implicated_via_orthology)
Disease	amygdala volume change measurement	SPATA31C2 SPATA31C1	4.11e-03	16	178	2	EFO_0021490
Disease	thyroid volume	IGF1R DNAH5	4.11e-03	16	178	2	EFO_0004865
Disease	Glioblastoma Multiforme	INSRR BRD2 HES1 CTNND2	4.65e-03	111	178	4	C1621958
Disease	response to platinum based chemotherapy	ODAD2 NRXN3	5.20e-03	18	178	2	EFO_0004647
Disease	Adrenocortical carcinoma	RRM1 IGF1R	5.20e-03	18	178	2	C0206686
Disease	Bone marrow hypocellularity	FANCA FANCI	5.20e-03	18	178	2	C1855710
Disease	Malignant neoplasm of breast	MYH1 TANK WWOX FRMPD1 SPTLC1 NUP214 CNNM4 IGF1R FAM83F MACF1 ZFYVE26 HES1 DHX32 USP54	5.75e-03	1074	178	14	C0006142
Disease	ovulation	FANCA FANCI	5.78e-03	19	178	2	GO_0030728
Disease	reasoning	WWOX ANKRD33	5.78e-03	19	178	2	EFO_0004350

Protein segments in the cluster

Peptide	Gene	Start	Entry
FRVQAVCRNDMRSDF	PTPRG	421	P23470
AQLSIADRATIANMC	ACO1	286	P21399
AFQNLMKDCEAEVRA	PPP2R1A	286	P30153
AREQYEQMARSRKCQ	BAHCC1	2596	Q9P281
FRQACERALEARMNF	CNTRL	886	Q7Z7A1
GTMNNNFCRALVDRR	ASCL5	71	Q7RTU5
FSGLFQRCVDVMIAR	BTBD16	191	Q32M84
TQFKRRSCQMEFEEG	DUSP8	581	Q13202
SAESRMILDAFAQQC	BEND4	161	Q6ZU67
MILDAFAQQCSRVLS	BEND4	166	Q6ZU67
SNARCRRTETMFNAC	AJM1	666	C9J069
MENVATIAASRLCRA	ACOT11	246	Q8WXI4
ETEMQSYRCRLNAAR	ANKRD36B	1036	Q8N2N9
EAQMINRFCFQVTRL	ASB6	231	Q9NWX5
ISQDVERFCRQLSSM	ABCD4	146	O14678
RARDECSRLQDKMNF	ANKRD26	1036	Q9UPS8
LNCSALRMADVIRAE	DHX32	576	Q7L7V1
DRVVCAVATALRNMA	CTNND2	906	Q9UQB3
QCFSEADRDIMTLAN	ASTE1	136	Q2TB18
QRAVDLLYAMCDRSN	AP2A2	386	O94973
MRCGDLLAASQVVNR	NUP93	326	Q8N1F7
QVEMFCQREAERCTG	RAET1E	121	Q8TD07
EERDARTVFCMQLAA	RBM23	161	Q86U06
FVTMADRAAAERACK	RBM24	56	Q9BX46
VKFARSSQACRAMEE	RBM45	71	Q8IUH3
KAAMRNRCADLTAVD	ANKRD33	206	Q7Z3H0
NICELAARMLFSAVE	NR2F2	211	P24468
CMDDLNNVAATARVL	NVL	391	O15381
CLQFTANALALAMER	PSMB6	186	P28072
FENFLVDMARVCNTT	ITPR2	1451	Q14571
MSAQGDCEFLVQRAR	INTS10	1	Q9NVR2
CFKLRAFTDNRDDMA	INTS10	571	Q9NVR2
DATAAYQELCRQRMA	PTPRN2	661	Q92932
SCIRTRELQSMADQE	PYCR1	261	P32322
QAVNFLRMSARVDAV	CHMP1B	61	Q7LBR1
ASDVRINFDKFRNCM	MEIOB	231	Q8N635
EQRQMILTGCVAFAR	RELCH	576	Q9P260
EIMDSLRRCLSQQAD	FANCI	586	Q9NVI1
LSRFQSNRMDDQRCC	GPSM2	496	P81274
RMVDACASFLTEALN	KLHL6	156	Q8WZ60
LVNAAVYSCRDAEMR	LPAR2	286	Q9HBW0
RLDTMNTTCVDRFIN	NCBP1	401	Q09161
FTTVSCRMLNRASED	ITIH5	66	Q86UX2
CRMLNRASEDQDIEF	ITIH5	71	Q86UX2
SMCEAFFQQEERARA	SPINK5	471	Q9NQ38
LDRFQAAVQTTCDLM	PHKA1	686	P46020
NARMSACLALERVAA	METTL25	451	Q8N6Q8
VALCFDRIATQVRMN	KIAA1109	1756	Q2LD37
LQETMRCVCRFDNRT	GAPVD1	1181	Q14C86
EDANTVAAALRVCDM	KDM8	111	Q8N371
FEINASSRDLCSQVM	DDX54	576	Q8TDD1
FVHRDLAARNCMVAE	IGF1R	1131	P08069
EAERGFNLMNIICTR	KIAA1586	706	Q9HCI6
QNIDVVLNRRSCMAA	NXF1	241	Q9UBU9
VRNASSEEIQRAFAM	NXF1	536	Q9UBU9
DIDIILNRRNCMAAT	NXF5	136	Q9H1B4
FEAREINLNACIAQM	OR51F2	101	Q8NH61
VLVAMAFDRFVAICN	OR51T1	116	Q8NGJ9
FAMEALSCIRDNEIQ	DNAH8	1121	Q96JB1
EVSRACDFLLSRQMA	LSS	611	P48449
VDGRVQLRFSMDCAE	NRXN3	81	Q9Y4C0
NEDRCFRVDMVQAAL	MRGPRD	171	Q8TDS7
LEMCVDARTFGNEAR	KMT2E	391	Q8IZD2
AAAAAALRRQMASQA	NUP214	1091	P35658
QMQLADRCFSRAGSV	LHX4	61	Q969G2
SARARTDLLNVCMNA	FOLR3	26	P41439
CVDAALLATQMDRVN	MSLN	326	Q13421
ALRNLARQCSDSSAM	GCN1	321	Q92616
FSVELCMNREDDTAR	LRRC42	51	Q9Y546
DLMIDVERTNAACAA	MYH1	1431	P12882
DSVRNNLRSALTEMC	MED17	96	Q9NVC6
NFMRQECLDSRFVFD	PSMA1	86	P25786
ERMQCVAAFAVSAVA	OSBPL1A	601	Q9BXW6
RRDFLCEASIMGQFD	EPHA7	676	Q15375
CTDEMFRDRRCNTQA	ITGB4	51	P16144
RITSNAMINACRDFL	OSBP	266	P22059
RITSNAMINACRDFL	OSBP2	361	Q969R2
CRVREMFSQLADLDD	MACF1	5131	Q9UPN3
CRNLIAFTMDLRSDD	MED16	41	Q9Y2X0
AMCRDAGRALQEAVS	MEI1	411	Q5TIA1
LLEAMLNRCAEFSQT	MEI1	461	Q5TIA1
SEQLCFFVQARMEIA	KICS2	126	Q96MD2
MCLFVTQFQRLRDGD	PXDNL	1216	A1KZ92
ANLTFARCLEMNLQD	DNAH1	1126	Q9P2D7
FEQERNVRTAMTNRA	CXXC1	616	Q9P0U4
QSVEVVCFRDRTMQG	ATG7	261	O95352
MLQLSEFLCEEFRNR	CPN1	96	P15169
QSQAMVRSVARQVCE	COL14A1	1611	Q05707
SALEDCAQEQMRLRA	FGL1	21	Q08830
QSCSDVLQERFAVEM	FRMPD1	286	Q5SYB0
LADGVMQCSFRRNIT	FRRS1	296	Q6ZNA5
VARLMAQAFESCQLD	FANCA	411	O15360
RNITNRSDCMAANYR	CACNA1I	1341	Q9P0X4
NQSVCSRMEAAEQAR	CEP250	626	Q9BV73
CALANMTEQIRQDRS	COL6A2	136	P12110
VEAMQAESCYQLARS	CTR9	301	Q6PD62
CDLEVEGFRATMAQR	CENPM	131	Q9NSP4
VCFQTREILDAMNRD	GK	406	P32189
FVHRDLAARNCMVSQ	INSRR	1111	P14616
NAMAACRSFQRALEL	DNAJC7	111	Q99615
QCAARVASRAEMLGA	IRAG2	286	Q12912
VLAFAQRERIQECMS	FOXR2	286	Q6PJQ5
ARCNMEEAVRSVAFS	EML6	361	Q6ZMW3
LQQALEACSTERERM	EME2	321	A4GXA9
MALNTRFAEVECLAE	CHD4	1816	Q14839
QAAICLLANMAVDRS	SEC24B	1016	O95487
ARDFNIDKAREIMCQ	SEC14L1	286	Q92503
QEGVFRSNCMDCLDR	SACM1L	381	Q9NTJ5
LMQSCSVLDLNAFER	RYR2	3796	Q92736
CAVADMVRLFQAEDS	IPO13	141	O94829
ERFMVKQAENICRQA	CNTD1	81	Q8N815
NAADFVRMCLTRDQH	MAP3K19	1296	Q56UN5
ENLRDALDCMFDARI	DNAH5	4426	Q8TE73
LNQCRSAEEALRMFA	LRRC43	641	Q8N309
NNIRATCFNSDIVLM	LGSN	136	Q5TDP6
RMCALNENIDRVVFV	PANK1	531	Q8TE04
RAGFSECMNEVTRFL	HES1	111	Q14469
RLVAQPACMAEDAFA	RTKN2	276	Q8IZC4
SECSMVRREAAFILQ	RTTN	1426	Q86VV8
RCGEMAQAASAAVTR	VARS1	681	P26640
DKDSVNCARQEAVRM	USP9X	836	Q93008
VRAVRDMLAVACVNQ	TRIM47	366	Q96LD4
CMRANLQATSEDVRG	SPATA31C2	811	B4DYI2
RSENVDMNSNRCLSV	SOCS5	26	O75159
MACAAARSPADQDRF	SRP19	1	P09132
FRENEDSCVTFMRAA	DNTT	181	P04053
TNARLDERIFAMCQV	SEC24A	916	O95486
MRDFSLAQETCQLAI	ODAD2	476	Q5T2S8
VSAVCLDMQSLEQRR	SLC9A3	591	P48764
AANDSVFVENCRRLM	PREX1	891	Q8TCU6
VFVENCRRLMALSSA	PREX1	896	Q8TCU6
MCVDARTFGNDARFI	SETD5	336	Q9C0A6
QMARVIFNRDGCSVL	SHLD1	146	Q8IYI0
NQTAARAFRKQMEDC	ST8SIA1	71	Q92185
ISARQLCADIAMGFR	CD84	206	Q9UIB8
FRQACMDRDSAVKEL	TANK	16	Q92844
SCIRTRELQSMADQE	PYCR2	261	Q96C36
EAVANRLFEMASRQS	RRP1	301	P56182
TCMRANLQATSEDVR	SPATA31C1	816	P0DKV0
VMTSCRELDNNRSAL	RASGRF1	886	Q13972
LNDNVRETFLKDMCR	SETD1A	101	O15047
EMCQDLQLTDFRIRN	FAM83F	206	Q8NEG4
QRLNELRDAAYCFMS	KBTBD11	246	O94819
NMFYIVACDNRDQRR	RNASE2	131	P10153
DDSEQTLRRDSLMCF	STK36	576	Q9NRP7
VDQCMNRSIALTQAR	SPTLC1	416	O15269
VQLQRAMAAEAEASR	STOM	201	P27105
VEAVSRRMANLAFCI	PIGW	361	Q7Z7B1
AQEFAADVRLMFSNC	BRD2	411	P25440
YAACNEEVRSALQRM	ADGRD2	901	Q7Z7M1
MDNRFATAFVIACVL	CLDND1	1	Q9NY35
VCADSRANIRAQMDG	CILP2	251	Q8IUL8
QDCFMIRSDAILDFN	CNNM4	381	Q6P4Q7
AQCFLRVDDESMQRF	PRPF8	1226	Q6P2Q9
RNMNQLRAEERFCDV	ZBTB12	21	Q9Y330
VLVRMCRAYNADNRT	RORC	361	P51449
FRDQAIVSAVANRMD	POLR3C	246	Q9BUI4
IAAVFQDNRMIAVCQ	MRPL10	86	Q7Z7H8
ERNTAAMVCSLENRD	RRM1	771	P23921
MNRAQFEQLCASLLA	HSPA4L	301	O95757
LMQSCSVLDLNAFER	RYR3	3686	Q15413
AARMVAAATNNLCEA	TLN1	2396	Q9Y490
KELCAMSEEQFRQRS	SPDEF	181	O95238
FRAVVSRQCCEEVMA	SPDYC	161	Q5MJ68
IDQDAQIFMRTCSEA	STX18	96	Q9P2W9
ACENLRNLNMETTRT	TRIM51	151	Q9BSJ1
AESMRRLEDAFVNCK	SYCE3	56	A1L190
RQICTSSLMERFLQD	ZDBF2	36	Q9HCK1
AKMCQFCEEAAARRQ	PIK3CD	141	O00329
FTMAENLANCERLIE	SMTNL2	416	Q2TAL5
VILACRNMARASEAV	WWOX	151	Q9NZC7
MFLSRALEEIQTCND	TEX11	706	Q8IYF3
DSETQLRRDMVFCQT	PREX2	1256	Q70Z35
RMNLQTATATCFDAA	RGS16	141	O15492
RMLLEVCQFSRDASV	SPTB	2006	P11277
RECRKMFQSASALEA	ZSCAN22	271	P10073
QESRMEVLFACAEAL	ZSWIM8	766	A7E2V4
IVERLCNSVFSMAAR	ZZEF1	1021	O43149
NQRCDRGSRDMFTEF	SLC9C2	926	Q5TAH2
CITCRVAFRDADMQR	ZNF622	6	Q969S3
MVVCRENSDTRVFQL	TBCCD1	446	Q9NVR7
FSMVLCCAIRNSRDV	TSPAN2	206	O60636
RRVFEMVVNTACKEN	SMC5	1031	Q8IY18
RLGDSELAMVCSQRN	WDR91	236	A4D1P6
QCTQVRVEFMDDTSR	RPS28	26	P62857
LCRDVMQETFRNLAS	ZNF433	31	Q8N7K0
DAAMTYCRAARQLVE	ZFYVE26	2401	Q68DK2
DATCLQLAMQADARA	TRPM4	651	Q8TD43
SRSVQQFLAMCDRGE	USP54	1501	Q70EL1
KRAINEMSVECNFRE	ZBED4	906	O75132
AIARCEQMAQERGES	MYO7B	1261	Q6PIF6