Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionNADP+ binding

AKR1C1 AKR1C2 GMDS AKR1C3

1.11e-0691974GO:0070401
GeneOntologyMolecularFunctionandrosterone dehydrogenase (B-specific) activity

AKR1C1 AKR1C2 AKR1C3

3.76e-0641973GO:0047042
GeneOntologyMolecularFunctionketoreductase activity

AKR1C1 AKR1C2 AKR1C3

3.76e-0641973GO:0045703
GeneOntologyMolecularFunctionchlordecone reductase activity

AKR1C1 AKR1C2 AKR1C3

3.76e-0641973GO:0047743
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR1C1 AKR1C2 AKR1B1 AKR1C3

8.51e-06141974GO:0004032
GeneOntologyMolecularFunctionretinal dehydrogenase activity

AKR1C1 AKR1C2 AKR1B1 AKR1C3

8.51e-06141974GO:0001758
GeneOntologyMolecularFunctiontrans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

9.32e-0651973GO:0047115
GeneOntologyMolecularFunction15-hydroxyprostaglandin-D dehydrogenase (NADP+) activity

AKR1C1 AKR1C2 AKR1C3

9.32e-0651973GO:0047020
GeneOntologyMolecularFunction17-beta-ketosteroid reductase (NADPH) activity

AKR1C1 AKR1C2 AKR1C3

9.32e-0651973GO:0072555
GeneOntologyMolecularFunction17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

9.32e-0651973GO:0047006
GeneOntologyMolecularFunctionlithocholic acid binding

AKR1C1 AKR1C2 AKR1C3

9.32e-0651973GO:1902121
GeneOntologyMolecularFunctionketosteroid monooxygenase activity

AKR1C1 AKR1C2 AKR1C3

9.32e-0651973GO:0047086
GeneOntologyMolecularFunctionDelta4-3-oxosteroid 5beta-reductase activity

AKR1C1 AKR1C2 AKR1C3

9.32e-0651973GO:0047787
GeneOntologyMolecularFunctiongeranylgeranyl reductase activity

AKR1C1 AKR1C2 AKR1C3

1.85e-0561973GO:0045550
GeneOntologyMolecularFunction17-beta-hydroxysteroid dehydrogenase (NADP+) activity

AKR1C1 AKR1C2 AKR1C3

3.22e-0571973GO:0072582
GeneOntologyMolecularFunction5alpha-androstane-3beta,17beta-diol dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

5.11e-0581973GO:0047024
GeneOntologyMolecularFunctionandrosterone dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

5.11e-0581973GO:0047023
GeneOntologyMolecularFunctionenone reductase activity

AKR1C1 AKR1C2 AKR1C3

5.11e-0581973GO:0035671
GeneOntologyMolecularFunctionandrostan-3-alpha,17-beta-diol dehydrogenase activity

AKR1C1 AKR1C2 AKR1C3

7.60e-0591973GO:0047044
GeneOntologyMolecularFunctionprostaglandin H2 endoperoxidase reductase activity

AKR1B1 AKR1C3

9.68e-0521972GO:0036130
GeneOntologyMolecularFunctiontestosterone 17-beta-dehydrogenase (NADP+) activity

AKR1C1 AKR1C2 AKR1C3

1.08e-04101973GO:0047045
GeneOntologyMolecularFunctionbile acid binding

AKR1C1 AKR1C2 AKR1C3

1.08e-04101973GO:0032052
GeneOntologyMolecularFunctionalcohol dehydrogenase (NADP+) activity

AKR1C1 AKR1C2 AKR1B1 AKR1C3

1.35e-04271974GO:0008106
GeneOntologyMolecularFunction1-phosphatidylinositol-3-kinase activity

PIK3CD PIK3CG PIK3R1

1.47e-04111973GO:0016303
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.66e-04321974GO:0004033
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor

AKR1C1 AKR1C2 AKR1B1 AKR1C3

3.38e-04341974GO:0016628
GeneOntologyMolecularFunctionsteroid binding

AKR1C1 AKR1C2 OSBPL9 OSBPL8 OSBPL11 UGT1A8 AKR1C3

3.57e-041331977GO:0005496
GeneOntologyMolecularFunctionindanol dehydrogenase activity

AKR1C1 AKR1C2

5.74e-0441972GO:0047718
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

SQLE AKR1C1 AKR1C2 AKR1C3

6.36e-04401974GO:0016709
GeneOntologyMolecularFunctionestradiol 17-beta-dehydrogenase [NAD(P)+] activity

AKR1C1 AKR1C2 AKR1C3

9.53e-04201973GO:0004303
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor

AKR1C1 AKR1C2 AKR1B1 AKR1C3

1.27e-03481974GO:0016620
GeneOntologyMolecularFunctionall-trans-retinol dehydrogenase (NAD+) activity

AKR1C1 AKR1C2 AKR1C3

1.64e-03241973GO:0004745
GeneOntologyMolecularFunction1-phosphatidylinositol-4-phosphate 3-kinase activity

PIK3CD PIK3CG

1.97e-0371972GO:0035005
GeneOntologyMolecularFunction1-phosphatidylinositol-4,5-bisphosphate 3-kinase activity

PIK3CD PIK3CG

1.97e-0371972GO:0046934
GeneOntologyMolecularFunctionphosphatidylinositol kinase activity

PIK3CD PIK3CG PIK3R1

2.08e-03261973GO:0052742
GeneOntologyMolecularFunctionalcohol dehydrogenase (NAD+) activity

AKR1C1 AKR1C2 AKR1C3

2.08e-03261973GO:0004022
GeneOntologyMolecularFunctionNADPH binding

AKR1C1 AKR1C2 AKR1C3

2.08e-03261973GO:0070402
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the aldehyde or oxo group of donors

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.26e-03561974GO:0016903
GeneOntologyMolecularFunctionoxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor

AKR1C1 AKR1C2 AIFM2 AKR1C3

2.91e-03601974GO:0016655
GeneOntologyMolecularFunctionalcohol dehydrogenase [NAD(P)+] activity

AKR1C1 AKR1C2 AKR1C3

3.16e-03301973GO:0018455
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors

AKR1C1 AKR1C2 AKR1B1 AKR1C3

3.28e-03621974GO:0016627
GeneOntologyMolecularFunctionNADP binding

AKR1C1 AKR1C2 GMDS AKR1C3

3.28e-03621974GO:0050661
GeneOntologyBiologicalProcessdaunorubicin metabolic process

AKR1C1 AKR1C2 AKR1B1 AKR1C3

1.00e-0691984GO:0044597
GeneOntologyBiologicalProcessdoxorubicin metabolic process

AKR1C1 AKR1C2 AKR1B1 AKR1C3

1.65e-06101984GO:0044598
GeneOntologyBiologicalProcesspolyketide metabolic process

AKR1C1 AKR1C2 AKR1B1 AKR1C3

1.65e-06101984GO:0030638
GeneOntologyBiologicalProcessaminoglycoside antibiotic metabolic process

AKR1C1 AKR1C2 AKR1B1 AKR1C3

1.65e-06101984GO:0030647
GeneOntologyBiologicalProcessresponse to jasmonic acid

AKR1C1 AKR1C2 AKR1C3

3.46e-0641983GO:0009753
GeneOntologyBiologicalProcessprogesterone catabolic process

AKR1C1 AKR1C2 AKR1C3

3.46e-0641983GO:0006709
GeneOntologyBiologicalProcessC21-steroid hormone catabolic process

AKR1C1 AKR1C2 AKR1C3

3.46e-0641983GO:0008208
GeneOntologyBiologicalProcesscellular response to jasmonic acid stimulus

AKR1C1 AKR1C2 AKR1C3

3.46e-0641983GO:0071395
GeneOntologyBiologicalProcesssesquiterpenoid catabolic process

AKR1C1 AKR1C2 AKR1C3

8.59e-0651983GO:0016107
GeneOntologyBiologicalProcessolefinic compound catabolic process

AKR1C1 AKR1C2 AKR1C3

8.59e-0651983GO:0120256
GeneOntologyBiologicalProcessfarnesol metabolic process

AKR1C1 AKR1C2 AKR1C3

8.59e-0651983GO:0016487
GeneOntologyBiologicalProcessfarnesol catabolic process

AKR1C1 AKR1C2 AKR1C3

8.59e-0651983GO:0016488
GeneOntologyBiologicalProcessnegative regulation of isoprenoid metabolic process

AKR1C1 AKR1C2 AKR1C3

8.59e-0651983GO:0045827
GeneOntologyBiologicalProcessnegative regulation of retinoic acid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

8.59e-0651983GO:1900053
GeneOntologyBiologicalProcesssesquiterpenoid metabolic process

AKR1C1 AKR1C2 AKR1C3

1.71e-0561983GO:0006714
GeneOntologyBiologicalProcesspolyprenol catabolic process

AKR1C1 AKR1C2 AKR1C3

1.71e-0561983GO:0016095
GeneOntologyBiologicalProcessresponse to prostaglandin D

AKR1C1 AKR1C2 AKR1C3

2.96e-0571983GO:0071798
GeneOntologyBiologicalProcesscellular response to prostaglandin D stimulus

AKR1C1 AKR1C2 AKR1C3

2.96e-0571983GO:0071799
GeneOntologyBiologicalProcessregulation of retinoic acid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

2.96e-0571983GO:1900052
GeneOntologyBiologicalProcesshormone catabolic process

AKR1C1 AKR1C2 UGT1A8 AKR1C3

4.34e-05211984GO:0042447
GeneOntologyBiologicalProcessglycoside metabolic process

AKR1C1 AKR1C2 AKR1B1 AKR1C3

5.26e-05221984GO:0016137
GeneOntologyBiologicalProcesstertiary alcohol metabolic process

AKR1C1 AKR1C2 AKR1B1 AKR1C3

5.26e-05221984GO:1902644
GeneOntologyBiologicalProcessregulation of isoprenoid metabolic process

AKR1C1 AKR1C2 AKR1C3

9.95e-05101983GO:0019747
GeneOntologyBiologicalProcessnegative regulation of vitamin metabolic process

AKR1C1 AKR1C2 AKR1C3

9.95e-05101983GO:0046137
GeneOntologyBiologicalProcessregulation of testosterone biosynthetic process

AKR1C1 AKR1C2 AKR1C3

1.36e-04111983GO:2000224
GeneOntologyBiologicalProcessterpenoid catabolic process

AKR1C1 AKR1C2 AKR1C3

1.36e-04111983GO:0016115
GeneOntologyBiologicalProcessprostaglandin metabolic process

AKR1C1 AKR1C2 PLAA AKR1B1 AKR1C3

1.99e-04561985GO:0006693
GeneOntologyBiologicalProcessprostanoid metabolic process

AKR1C1 AKR1C2 PLAA AKR1B1 AKR1C3

2.16e-04571985GO:0006692
GeneOntologyBiologicalProcessretinoic acid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

2.93e-04141983GO:0002138
GeneOntologyBiologicalProcessisoprenoid catabolic process

AKR1C1 AKR1C2 AKR1C3

2.93e-04141983GO:0008300
GeneOntologyBiologicalProcesssteroid catabolic process

AKR1C1 AKR1C2 UGT1A8 AKR1C3

3.05e-04341984GO:0006706
GeneOntologyBiologicalProcessditerpenoid biosynthetic process

AKR1C1 AKR1C2 AKR1C3

3.64e-04151983GO:0016102
GeneOntologyBiologicalProcesstestosterone biosynthetic process

AKR1C1 AKR1C2 AKR1C3

4.45e-04161983GO:0061370
GeneOntologyBiologicalProcessnegative regulation of hormone metabolic process

AKR1C1 AKR1C2 AKR1C3

4.45e-04161983GO:0032351
GeneOntologyBiologicalProcessicosanoid metabolic process

AKR1C1 AKR1C2 NLRC4 PLAA SYK AKR1B1 AKR1C3

4.51e-041421987GO:0006690
GeneOntologyBiologicalProcesssecondary metabolic process

AKR1C1 AKR1C2 AKR1B1 UGT1A8 AKR1C3

4.62e-04671985GO:0019748
GeneOntologyBiologicalProcessretinoic acid metabolic process

AKR1C1 AKR1C2 UGT1A8 AKR1C3

5.74e-04401984GO:0042573
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class I

PIK3CD PIK3CG PIK3R1

6.84e-0591993GO:0097651
GeneOntologyCellularComponentphosphatidylinositol 3-kinase complex, class IA

PIK3CD PIK3CG PIK3R1

6.84e-0591993GO:0005943
DomainALDOKETO_REDUCTASE_1

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.45e-06101984PS00798
DomainALDOKETO_REDUCTASE_2

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.45e-06101984PS00062
DomainALDOKETO_REDUCTASE_3

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.45e-06101984PS00063
DomainAldo/ket_reductase_CS

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.45e-06101984IPR018170
DomainAldo/keto_reductase

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.45e-06101984IPR020471
DomainARM-type_fold

USP34 SMG1 VPS11 NOC2L UNC45A ARMC2 PLAA PIK3CD PIK3CG INTS7 UBR4 RTTN WDFY4 RANBP17 ARID2

3.51e-0633919815IPR016024
DomainTPR-like_helical_dom

TANC2 VPS11 RGPD1 TMTC2 UNC45A CDC16 NRDE2 CAPN7 CSTF3 SEL1L2 LONRF3 CDC27

7.50e-0623319812IPR011990
Domain-

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.02e-051619843.20.20.100
DomainNADP_OxRdtase_dom

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.62e-05171984IPR023210
DomainAldo_ket_red

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.62e-05171984PF00248
DomainAldo/ket_red/Kv-b

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.62e-05171984IPR001395
Domain-

TANC2 VPS11 RGPD1 TMTC2 UNC45A CDC16 NRDE2 CSTF3 SEL1L2 LONRF3

7.49e-05207198101.25.40.10
DomainZINC_FINGER_C2H2_2

HIVEP1 VEZF1 ZNF268 ZNF177 ZNF831 ZNF702P ZNF440 ZNF836 ZNF117 ZNF433 ZFP62 ZNF211 RLF ZNF26 ZNF425 ZNF728 ARID2 ZNF816 ZNF69 ZNF639 ZNF292

7.91e-0577519821PS50157
DomainWD40_repeat_dom

VPS11 NOL10 NEDD1 PLAA NWD1 WDR36 UBR4 NOL11 WDFY4 WDHD1 WDR12 EIF2A

8.16e-0529719812IPR017986
DomainZINC_FINGER_C2H2_1

HIVEP1 VEZF1 ZNF268 ZNF177 ZNF831 ZNF702P ZNF440 ZNF836 ZNF117 ZNF433 ZFP62 ZNF211 RLF ZNF26 ZNF425 ZNF728 ARID2 ZNF816 ZNF69 ZNF639 ZNF292

8.20e-0577719821PS00028
DomainZnf_C2H2

HIVEP1 VEZF1 ZNF268 ZNF177 ZNF831 ZNF702P ZNF440 ZNF836 ZNF117 ZNF433 ZFP62 ZNF211 RLF ZNF26 ZNF425 ZNF728 ARID2 ZNF816 ZNF69 ZNF639 ZNF292

1.34e-0480519821IPR007087
DomainZnF_C2H2

HIVEP1 VEZF1 ZNF268 ZNF177 ZNF831 ZNF702P ZNF440 ZNF836 ZNF117 ZNF433 ZFP62 ZNF211 RLF ZNF26 ZNF425 ZNF728 ARID2 ZNF816 ZNF69 ZNF639 ZNF292

1.41e-0480819821SM00355
Domainzf-C2H2

HIVEP1 VEZF1 ZNF268 ZNF177 ZNF702P ZNF440 ZNF836 ZNF117 ZNF433 ZFP62 ZNF211 RLF ZNF26 ZNF425 ZNF728 ZNF816 ZNF69 ZNF639 ZNF292

1.51e-0469319819PF00096
DomainZnf_C2H2/integrase_DNA-bd

HIVEP1 VEZF1 ZNF268 ZNF177 ZNF831 ZNF440 ZNF836 ZNF117 ZNF433 ZFP62 ZNF211 RLF ZNF26 ZNF425 ZNF728 ZNF816 ZNF69 ZNF639 ZNF292

1.54e-0469419819IPR013087
Domain-

VPS11 NOL10 NEDD1 PLXNB2 PLAA NWD1 WDR36 NOL11 WDFY4 WDHD1 WDR12 EIF2A

2.37e-04333198122.130.10.10
DomainOxysterol-bd_CS

OSBPL9 OSBPL8 OSBPL11

2.41e-04121983IPR018494
DomainOxysterol_BP

OSBPL9 OSBPL8 OSBPL11

2.41e-04121983PF01237
DomainOxysterol-bd

OSBPL9 OSBPL8 OSBPL11

2.41e-04121983IPR000648
DomainOSBP

OSBPL9 OSBPL8 OSBPL11

2.41e-04121983PS01013
DomainWD40/YVTN_repeat-like_dom

VPS11 NOL10 NEDD1 PLXNB2 PLAA NWD1 WDR36 NOL11 WDFY4 WDHD1 WDR12 EIF2A

2.50e-0433519812IPR015943
DomainZnf_C2H2-like

HIVEP1 VEZF1 ZNF268 ZNF177 ZNF831 ZNF440 ZNF836 ZNF117 ZNF433 ZFP62 ZNF211 RLF ZNF26 ZNF425 ZNF728 ARID2 ZNF816 ZNF69 ZNF639 ZNF292

3.18e-0479619820IPR015880
Domain-

HIVEP1 VEZF1 ZNF268 ZNF831 ZNF440 ZNF836 ZNF117 ZNF433 ZFP62 ZNF211 RLF ZNF26 ZNF425 ZNF728 ZNF816 ZNF69 ZNF639 ZNF292

3.40e-04679198183.30.160.60
DomainTPR

TANC2 RGPD1 TMTC2 UNC45A CDC16 LONRF3 CDC27

4.55e-041291987SM00028
DomainPI3/4_kinase_CS

SMG1 PIK3CD PIK3CG

4.86e-04151983IPR018936
Domainzf-C2H2_6

ZNF440 ZNF836 ZNF117 ZNF433 ZFP62 ZNF211 ZNF26 ZNF425 ZNF728 ZNF816 ZNF69

5.45e-0431419811PF13912
DomainTPR_repeat

TANC2 RGPD1 TMTC2 UNC45A CDC16 LONRF3 CDC27

5.46e-041331987IPR019734
Domain-

SMG1 PIK3CD PIK3CG

5.94e-041619831.10.1070.11
DomainPI3Kc

SMG1 PIK3CD PIK3CG

5.94e-04161983SM00146
DomainPH_dom-like

ARHGAP42 TBC1D2B RGPD1 ARHGEF16 ANLN OSBPL9 OSBPL8 OSBPL11 PHLPP1 FRMPD2 WDFY4 TNS4 PHLPP2

6.43e-0442619813IPR011993
DomainPI3K_ABD

PIK3CD PIK3CG

6.62e-0441982PS51544
DomainPI3K_adapt-bd_dom

PIK3CD PIK3CG

6.62e-0441982IPR003113
DomainWD_REPEATS_1

NOL10 NEDD1 PLAA HERC2 NWD1 WDR36 WDFY4 WDHD1 WDR12 EIF2A

7.92e-0427819810PS00678
DomainWD_REPEATS_2

NOL10 NEDD1 PLAA HERC2 NWD1 WDR36 WDFY4 WDHD1 WDR12 EIF2A

8.15e-0427919810PS50082
DomainWD_REPEATS_REGION

NOL10 NEDD1 PLAA HERC2 NWD1 WDR36 WDFY4 WDHD1 WDR12 EIF2A

8.15e-0427919810PS50294
DomainPI3_PI4_kinase

SMG1 PIK3CD PIK3CG

8.51e-04181983PF00454
DomainPI3_4_KINASE_1

SMG1 PIK3CD PIK3CG

8.51e-04181983PS00915
DomainPI3_4_KINASE_2

SMG1 PIK3CD PIK3CG

8.51e-04181983PS00916
DomainPI3/4_kinase_cat_dom

SMG1 PIK3CD PIK3CG

8.51e-04181983IPR000403
DomainPI3_4_KINASE_3

SMG1 PIK3CD PIK3CG

8.51e-04181983PS50290
Domain-

ARHGAP42 TBC1D2B RGPD1 ARHGEF16 ANLN OSBPL9 OSBPL8 OSBPL11 PHLPP1 FRMPD2 TNS4 PHLPP2

9.85e-04391198122.30.29.30
DomainDUF3504

ZMYM2 ZMYM3

1.09e-0351982IPR021893
DomainTIF_beta_prop-like

WDHD1 EIF2A

1.09e-0351982IPR013979
DomaineIF2A

WDHD1 EIF2A

1.09e-0351982PF08662
DomainDUF3504

ZMYM2 ZMYM3

1.09e-0351982PF12012
DomainTPR-contain_dom

TANC2 RGPD1 TMTC2 UNC45A CDC16 LONRF3 CDC27

1.11e-031501987IPR013026
DomainApc4_WD40_dom

NWD1 WDR36 WDHD1

1.17e-03201983IPR024977
DomainANAPC4_WD40

NWD1 WDR36 WDHD1

1.17e-03201983PF12894
DomainKRAB

ZNF268 ZNF177 ZNF440 ZNF836 ZNF433 ZNF211 ZNF26 ZNF425 ZNF728 ZNF816 ZNF69

1.58e-0335819811PS50805
DomainKRAB

ZNF268 ZNF177 ZNF440 ZNF836 ZNF433 ZNF211 ZNF26 ZNF425 ZNF728 ZNF816 ZNF69

1.58e-0335819811PF01352
DomainNACHT

NLRP11 NLRC4 NLRP8

1.78e-03231983PS50837
DomainNACHT_NTPase

NLRP11 NLRC4 NLRP8

1.78e-03231983IPR007111
DomainTPR_REGION

TANC2 RGPD1 TMTC2 UNC45A CDC16 LONRF3 CDC27

1.92e-031651987PS50293
DomainTPR

TANC2 RGPD1 TMTC2 UNC45A CDC16 LONRF3 CDC27

1.92e-031651987PS50005
DomainKRAB

ZNF268 ZNF177 ZNF440 ZNF836 ZNF433 ZNF211 ZNF26 ZNF425 ZNF728 ZNF816 ZNF69

2.00e-0336919811SM00349
DomainKRAB

ZNF268 ZNF177 ZNF440 ZNF836 ZNF433 ZNF211 ZNF26 ZNF425 ZNF728 ZNF816 ZNF69

2.04e-0337019811IPR001909
DomainPI3K_Ras-bd_dom

PIK3CD PIK3CG

2.27e-0371982IPR000341
DomainZnf_MYM

ZMYM2 ZMYM3

2.27e-0371982IPR010507
DomainPI3K_rbd

PIK3CD PIK3CG

2.27e-0371982SM00144
DomainPI3K_rbd

PIK3CD PIK3CG

2.27e-0371982PF00794
DomainPI3K_RBD

PIK3CD PIK3CG

2.27e-0371982PS51546
Domainzf-FCS

ZMYM2 ZMYM3

2.27e-0371982PF06467
DomainTPR_8

TANC2 TMTC2 UNC45A CDC27

2.39e-03531984PF13181
DomainARM-like

SMG1 UNC45A ARMC2 PLAA INTS7 RTTN WDFY4 RANBP17 ARID2

2.42e-032701989IPR011989
DomainWD40_repeat

NOL10 NEDD1 PLAA HERC2 NWD1 WDR36 WDFY4 WDHD1 WDR12

2.54e-032721989IPR001680
DomainTPR_1

RGPD1 TMTC2 UNC45A CDC16 CDC27

2.70e-03901985IPR001440
DomainTPR_1

RGPD1 TMTC2 UNC45A CDC16 CDC27

2.70e-03901985PF00515
DomainLRR_6

NLRP11 FBXL5 PHLPP1 NLRP8

2.74e-03551984PF13516
DomainTRASH_dom

ZMYM2 ZMYM3

3.00e-0381982IPR011017
DomainTRASH

ZMYM2 ZMYM3

3.00e-0381982SM00746
DomainPI3K_C2

PIK3CD PIK3CG

3.00e-0381982SM00142
DomainPI3K_C2_dom

PIK3CD PIK3CG

3.00e-0381982IPR002420
DomainMan6P_isomerase_rcpt-bd_dom

ELAPOR2 IGF2R

3.00e-0381982IPR009011
DomainPI3K_C2

PIK3CD PIK3CG

3.00e-0381982PF00792
DomainPI3K_C2

PIK3CD PIK3CG

3.00e-0381982PS51547
DomainPH_DOMAIN

ARHGAP42 TBC1D2B ARHGEF16 ANLN OSBPL9 OSBPL8 OSBPL11 PHLPP1 PHLPP2

3.01e-032791989PS50003
DomainPH

ARHGAP42 TBC1D2B ARHGEF16 ANLN OSBPL9 OSBPL8 OSBPL11 PHLPP1

3.14e-032291988PF00169
DomainPI3Ka

PIK3CD PIK3CG

3.83e-0391982PF00613
DomainPI3Ka

PIK3CD PIK3CG

3.83e-0391982SM00145
Domain-

PIK3CD PIK3CG

3.83e-03919821.25.40.70
DomainSH2

CHN1 PIK3R1 SYK SHE TNS4

4.43e-031011985PF00017
DomainCNMP_BINDING_1

SLC9C1 CNGA1 KCNH4

4.64e-03321983PS00888
DomainCNMP_BINDING_2

SLC9C1 CNGA1 KCNH4

4.64e-03321983PS00889
DomainPI_Kinase

PIK3CD PIK3CG

4.76e-03101982IPR015433
DomainPInositide-3_kin_accessory_dom

PIK3CD PIK3CG

4.76e-03101982IPR001263
DomainPIK_HELICAL

PIK3CD PIK3CG

4.76e-03101982PS51545
DomaincNMP

SLC9C1 CNGA1 KCNH4

5.51e-03341983SM00100
DomaincNMP_binding

SLC9C1 CNGA1 KCNH4

5.51e-03341983PF00027
DomaincNMP-bd_dom

SLC9C1 CNGA1 KCNH4

5.98e-03351983IPR000595
DomainCNMP_BINDING_3

SLC9C1 CNGA1 KCNH4

5.98e-03351983PS50042
DomainSH2

CHN1 PIK3R1 SYK SHE TNS4

6.35e-031101985SM00252
DomainSH2

CHN1 PIK3R1 SYK SHE TNS4

6.59e-031111985PS50001
DomainSH2

CHN1 PIK3R1 SYK SHE TNS4

6.84e-031121985IPR000980
Domain-

CHN1 PIK3R1 SYK SHE TNS4

6.84e-0311219853.30.505.10
DomainFAD-dep_OxRdtase

SQLE GPD2

6.88e-03121982IPR006076
DomainDAO

SQLE GPD2

6.88e-03121982PF01266
PathwayWP_BENZOAPYRENE_METABOLISM

AKR1C1 AKR1C2 AKR1C3

6.18e-0591303M39344
PathwayKEGG_MEDICUS_ENV_FACTOR_METALS_TO_KEAP1_NRF2_SIGNALIG_PATHWAY

AKR1C1 AKR1C2 AKR1C3

6.18e-0591303M47817
PathwayKEGG_MEDICUS_ENV_FACTOR_BENZO_A_PYRENRE_TO_CYP_MEDIATED_METABOLISM

AKR1C1 AKR1C2 AKR1C3

1.20e-04111303M47812
PathwayREACTOME_ERYTHROPOIETIN_ACTIVATES_PHOSPHOINOSITIDE_3_KINASE_PI3K

PIK3CD PIK3CG PIK3R1

1.59e-04121303M27905
PathwayREACTOME_ERYTHROPOIETIN_ACTIVATES_PHOSPHOINOSITIDE_3_KINASE_PI3K

PIK3CD PIK3CG PIK3R1

1.59e-04121303MM15623
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

2.05e-04131303MM14747
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_24_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

2.05e-04131303M17842
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C1 AKR1C2 OSBPL9 AKR1C3

2.30e-04331304MM14737
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS

AKR1C1 AKR1C2 OSBPL9 AKR1C3

2.30e-04331304M5967
PathwayWP_GLUCOCORTICOID_BIOSYNTHESIS

AKR1C1 AKR1C2 AKR1C3

2.59e-04141303M46449
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

2.59e-04141303M27074
PathwayWP_MINERALOCORTICOID_BIOSYNTHESIS

AKR1C1 AKR1C2 AKR1C3

2.59e-04141303M46453
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_27_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

2.59e-04141303MM14748
PathwayBIOCARTA_ACH_PATHWAY

PIK3CG PIK3R1 TERT

2.59e-04141303M16884
PathwayBIOCARTA_ACH_PATHWAY

PIK3CG PIK3R1 TERT

2.59e-04141303MM1485
PathwayWP_FERROPTOSIS

AKR1C1 AKR1C2 AIFM2 AKR1C3 STEAP3

3.04e-04641305M39768
PathwayREACTOME_SYNTHESIS_OF_PROSTAGLANDINS_PG_AND_THROMBOXANES_TX

AKR1C1 AKR1C2 AKR1C3

3.22e-04151303MM14870
PathwayKEGG_MEDICUS_REFERENCE_BCR_BCAP_CD19_PI3K_SIGNALING_PATHWAY

PIK3CD PIK3R1 SYK

3.22e-04151303M47971
PathwayKEGG_MEDICUS_REFERENCE_DISASSEMBLY_OF_MCC

CDC16 BUB1B CDC27

4.74e-04171303M47888
PathwayREACTOME_SIGNALING_BY_ERYTHROPOIETIN

PIK3CD PIK3CG PIK3R1

4.74e-04171303MM15584
PathwayWP_MICROGLIA_PATHOGEN_PHAGOCYTOSIS_PATHWAY

PIK3CD PIK3CG PIK3R1 SYK

4.88e-04401304M39695
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

PIK3CD PIK3R1 PHLPP1 KIT NTRK2 PHLPP2

6.18e-041131306MM14783
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C1 AKR1C2 OSBPL9 AKR1C3

7.04e-04441304M499
PathwayWP_PROSTAGLANDIN_SYNTHESIS_AND_REGULATION

AKR1C1 AKR1C2 AKR1B1 AKR1C3

7.68e-04451304M39355
PathwayREACTOME_BILE_ACID_AND_BILE_SALT_METABOLISM

AKR1C1 AKR1C2 OSBPL9 AKR1C3

7.68e-04451304MM14751
PathwayREACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK

PIK3CD PIK3R1 PHLPP1 KIT NTRK2 PHLPP2

7.77e-041181306M713
PathwayBIOCARTA_NKCELLS_PATHWAY

PIK3R1 SYK KLRC1

7.79e-04201303M16355
PathwayKEGG_MEDICUS_PATHOGEN_EBV_LMP2A_TO_PI3K_SIGNALING_PATHWAY

PIK3CD SYK

8.29e-0451302M48997
PathwayWP_MICROGLIA_PATHOGEN_PHAGOCYTOSIS_PATHWAY

PIK3CD PIK3CG PIK3R1 SYK

8.35e-04461304MM15837
PathwayREACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS

CDC16 BUB1B CDC27

9.03e-04211303M489
PathwayBIOCARTA_RAC1_PATHWAY

CHN1 PIK3CG PIK3R1

9.03e-04211303M8601
PathwayREACTOME_REGULATION_OF_SIGNALING_BY_CBL

PIK3CD PIK3R1 SYK

9.03e-04211303MM15633
PathwayKEGG_MEDICUS_REFERENCE_SPINDLE_ASSEMBLY_CHECKPOINT_SIGNALING

CDC16 BUB1B CDC27

9.03e-04211303M47583
PathwayBIOCARTA_RAC1_PATHWAY

CHN1 PIK3CG PIK3R1

9.03e-04211303MM1463
PathwayREACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS

CDC16 BUB1B CDC27

9.03e-04211303MM14560
PathwayPID_PI3KCI_PATHWAY

PIK3CD PIK3CG PIK3R1 SYK

9.82e-04481304M141
PathwayREACTOME_REGULATION_OF_SIGNALING_BY_CBL

PIK3CD PIK3R1 SYK

1.04e-03221303M903
PathwayREACTOME_METABOLISM_OF_STEROIDS

SQLE AKR1C1 AKR1C2 OSBPL9 AKR1B1 AKR1C3

1.09e-031261306MM15553
PathwayKEGG_PROGESTERONE_MEDIATED_OOCYTE_MATURATION

PIK3CD PIK3CG PIK3R1 CDC16 CDC27

1.12e-03851305M3578
PathwayREACTOME_PREDNISONE_ADME

AKR1C1 AKR1C2 AKR1C3

1.19e-03231303MM16639
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

1.19e-03231303MM14741
PathwayREACTOME_SYNTHESIS_OF_BILE_ACIDS_AND_BILE_SALTS_VIA_7ALPHA_HYDROXYCHOLESTEROL

AKR1C1 AKR1C2 AKR1C3

1.19e-03231303M1926
PathwayREACTOME_GDP_FUCOSE_BIOSYNTHESIS

FPGT GMDS

1.24e-0361302MM15322
PathwayREACTOME_GDP_FUCOSE_BIOSYNTHESIS

FPGT GMDS

1.24e-0361302M27611
PathwayWP_IL2_SIGNALING_PATHWAY

PIK3CD PIK3CG PIK3R1 SYK TERT

1.25e-03871305MM15915
PathwayKEGG_MTOR_SIGNALING_PATHWAY

PIK3CD PIK3CG PIK3R1 EIF4E1B

1.33e-03521304M7561
PathwayBIOCARTA_BAD_PATHWAY

PIK3CG PIK3R1 KIT

1.35e-03241303MM1467
PathwayREACTOME_SIGNALING_BY_ERYTHROPOIETIN

PIK3CD PIK3CG PIK3R1

1.52e-03251303M27865
PathwayBIOCARTA_BAD_PATHWAY

PIK3CG PIK3R1 KIT

1.52e-03251303M85
PathwayBIOCARTA_NKCELLS_PATHWAY

PIK3R1 SYK KLRC1

1.52e-03251303MM1465
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

AKR1C1 AKR1C2 CNGA1 RGS9BP AKR1C3

1.60e-03921305MM14881
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

AKR1C1 AKR1C2 UGT1A8 AKR1C3

1.64e-03551304M14933
PathwayKEGG_INSULIN_SIGNALING_PATHWAY

PHKA1 PIK3CD PIK3CG PIK3R1 EXOC7 EIF4E1B

1.68e-031371306M18155
PathwayREACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A

CDC16 BUB1B CDC27

1.71e-03261303MM14697
PathwayREACTOME_APC_CDC20_MEDIATED_DEGRADATION_OF_NEK2A

CDC16 BUB1B CDC27

1.71e-03261303M1079
PathwayREACTOME_ACTIVATED_NTRK2_SIGNALS_THROUGH_PI3K

PIK3R1 NTRK2

1.72e-0371302M27910
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

USP34 MAP4 STXBP4 ANKHD1 AKR1C1 AKR1C2 PLAA ANLN PIK3CD PIK3R1 OSBPL11 DNA2 FAM135A COG4 NRDE2 ANK3 TMEM254 NOL11 INO80 WDFY4 SLC7A1 IGF2R WDHD1 TIMP3 GRAMD2B AKR1C3 CDC27

3.51e-1010842062711544199
Pubmed

Expression analysis of the aldo-keto reductases involved in the novel biosynthetic pathway of tetrahydrobiopterin in human and mouse tissues.

AKR1C1 AKR1C2 AKR1B1 AKR1C3

1.78e-086206419273550
Pubmed

Naturally occurring variants of human aldo-keto reductases with reduced in vitro metabolism of daunorubicin and doxorubicin.

AKR1C1 AKR1C2 AKR1B1 AKR1C3

8.21e-088206420837989
Pubmed

Aldo-keto reductase 1C subfamily genes in skin are UV-inducible: possible role in keratinocytes survival.

AKR1C1 AKR1C2 AKR1C3

2.05e-073206319320734
Pubmed

Aldo-keto reductases protect metastatic melanoma from ER stress-independent ferroptosis.

AKR1C1 AKR1C2 AKR1C3

2.05e-073206331780644
Pubmed

Altered expression of 3 alpha-hydroxysteroid dehydrogenases in human glaucomatous optic nerve head astrocytes.

AKR1C1 AKR1C2 AKR1C3

2.05e-073206313678667
Pubmed

Downregulation of PHLPP induced by endoplasmic reticulum stress promotes eIF2α phosphorylation and chemoresistance in colon cancer.

PHLPP1 EIF2A PHLPP2

2.05e-073206334663797
Pubmed

Aldo-keto reductases AKR1C1, AKR1C2 and AKR1C3 may enhance progesterone metabolism in ovarian endometriosis.

AKR1C1 AKR1C2 AKR1C3

2.05e-073206321232532
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ATP6AP1 NOC2L STXBP4 UNC45A RRM1 PLXNB2 PIK3R1 BUB1B OSBPL8 PDZD8 GMDS HERC2 DNA2 FAM135A WDR36 ANK3 UBR4 NOL11 SPG11 LGALS3BP AIFM2 IARS2 IGF2R DPP9 STEAP3 WDR12 EIF2A

2.50e-0714872062733957083
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

ATP6AP1 GTPBP6 VEZF1 MAP4 NOC2L ZMYM2 GON4L NOL10 UNC45A ANKHD1 BBX ANLN CDC16 OSBPL8 HERC2 NRDE2 WDR36 INTS7 NOL11 INO80 SRBD1 ARID2 CSTF3 WDR12 EIF2A CDC27 ZMYM3

2.85e-0714972062731527615
Pubmed

Phosphatidylinositol 3-kinase regulates human immunodeficiency virus type 1 replication following viral entry in primary CD4+ T lymphocytes and macrophages.

CXCR4 PIK3CD PIK3CG PIK3R1

5.70e-0712206412551992
Pubmed

Structure and activity of the murine type 5 17beta-hydroxysteroid dehydrogenase gene(1).

AKR1C1 AKR1C2 AKR1C3

8.16e-074206310500239
Pubmed

AKR1C isoforms represent a novel cellular target for jasmonates alongside their mitochondrial-mediated effects.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206319487289
Pubmed

Cloning and chromosomal localization of mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206314967952
Pubmed

Assignment of HSD17B5 encoding type 5 17 beta-hydroxysteroid dehydrogenase to human chromosome bands 10p15-->p14 and mouse chromosome 13 region A2 by in situ hybridization: identification of a new syntenic relationship.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206310393440
Pubmed

Localization of 20alpha-hydroxysteroid dehydrogenase mRNA in mouse brain by in situ hybridization.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206315193432
Pubmed

Mouse Akr1cl gene product is a prostaglandin D2 11-ketoreductase with strict substrate specificity.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206331479646
Pubmed

CD28 provides T-cell costimulation and enhances PI3K activity at the immune synapse independently of its capacity to interact with the p85/p110 heterodimer.

PIK3CD PIK3CG PIK3R1

8.16e-074206318006698
Pubmed

Isolation and characterization of a cDNA encoding mouse 3alpha-hydroxysteroid dehydrogenase: an androgen-inactivating enzyme selectively expressed in female tissues.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206316191478
Pubmed

Characterization of two isoforms of mouse 3(17)alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase family.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206315577209
Pubmed

Identification of an interleukin-3-regulated aldoketo reductase gene in myeloid cells which may function in autocrine regulation of myelopoiesis.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206310702227
Pubmed

Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206317034817
Pubmed

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206329764944
Pubmed

Characterization of rat and mouse NAD+-dependent 3alpha/17beta/20alpha-hydroxysteroid dehydrogenases and identification of substrate specificity determinants by site-directed mutagenesis.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206317888864
Pubmed

Mouse 17alpha-hydroxysteroid dehydrogenase (AKR1C21) binds steroids differently from other aldo-keto reductases: identification and characterization of amino acid residues critical for substrate binding.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206317442338
Pubmed

Sensing of Bacterial Cyclic Dinucleotides by the Oxidoreductase RECON Promotes NF-κB Activation and Shapes a Proinflammatory Antibacterial State.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206328329705
Pubmed

Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206319237748
Pubmed

Mefenamic acid enhances anticancer drug sensitivity via inhibition of aldo-keto reductase 1C enzyme activity.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206328259989
Pubmed

Crystallization and preliminary X-ray diffraction analysis of mouse 3(17)alpha-hydroxysteroid dehydrogenase.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206316511129
Pubmed

Localization of multiple human dihydrodiol dehydrogenase (DDH1 and DDH2) and chlordecone reductase (CHDR) genes in chromosome 10 by the polymerase chain reaction and fluorescence in situ hybridization.

AKR1C1 AKR1C2 AKR1C3

8.16e-07420637789999
Pubmed

Studies on a Tyr residue critical for the binding of coenzyme and substrate in mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21): structure of the Y224D mutant enzyme.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206320124700
Pubmed

Enzymatic properties of a member (AKR1C20) of the aldo-keto reductase family.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206316508162
Pubmed

Characterization and functional analysis of the 5'-flanking region of the mouse 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206315222881
Pubmed

Several distinct enzymes catalyze 20alpha-hydroxysteroid dehydrogenase activity in mouse liver and kidney.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206317629694
Pubmed

Cloning and characterization of two novel aldo-keto reductases (AKR1C12 and AKR1C13) from mouse stomach.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206310526179
Pubmed

Characterization of 17alpha-hydroxysteroid dehydrogenase activity (17alpha-HSD) and its involvement in the biosynthesis of epitestosterone.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206316018803
Pubmed

Reproductive phenotypes in mice with targeted disruption of the 20alpha-hydroxysteroid dehydrogenase gene.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206317272929
Pubmed

Involvement of 20alpha-hydroxysteroid dehydrogenase in the maintenance of pregnancy in mice.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206318667791
Pubmed

Stereospecific reduction of 5β-reduced steroids by human ketosteroid reductases of the AKR (aldo-keto reductase) superfamily: role of AKR1C1-AKR1C4 in the metabolism of testosterone and progesterone via the 5β-reductase pathway.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206321521174
Pubmed

Molecular cloning of multiple cDNAs encoding human enzymes structurally related to 3 alpha-hydroxysteroid dehydrogenase.

AKR1C1 AKR1C2 AKR1C3

8.16e-07420638274401
Pubmed

Identification of the oxidative 3alpha-hydroxysteroid dehydrogenase activity of rat Leydig cells as type II retinol dehydrogenase.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206310803568
Pubmed

AKR1C1 alleviates LPS‑induced ALI in mice by activating the JAK2/STAT3 signaling pathway.

AKR1C1 AKR1C2 AKR1C3

8.16e-074206334590152
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

NRIP1 SPEG TBC1D2B OSBPL8 NWD1 ZNF211 ANK3 SPG11 VPS13D CAPN7 ARID2 WDR12 CTPS1 ZNF292

1.84e-064972061436774506
Pubmed

Retinaldehyde is a substrate for human aldo-keto reductases of the 1C subfamily.

AKR1C1 AKR1C2 AKR1C3

2.03e-065206321851338
Pubmed

The catalytic PI3K isoforms p110gamma and p110delta contribute to B cell development and maintenance, transformation, and proliferation.

PIK3CD PIK3CG PIK3R1

2.03e-065206320200404
Pubmed

Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC.

CDC16 BUB1B CDC27

2.03e-065206310477750
Pubmed

Role of ERas in promoting tumour-like properties in mouse embryonic stem cells.

PIK3CD PIK3CG PIK3R1

2.03e-065206312774123
Pubmed

Rapid microtubule-independent dynamics of Cdc20 at kinetochores and centrosomes in mammalian cells.

CDC16 BUB1B CDC27

2.03e-065206312196507
Pubmed

Expression of progesterone metabolizing enzyme genes (AKR1C1, AKR1C2, AKR1C3, SRD5A1, SRD5A2) is altered in human breast carcinoma.

AKR1C1 AKR1C2 AKR1C3

2.03e-065206315212687
Pubmed

Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis.

AKR1C1 AKR1C2 AKR1C3

2.03e-065206316984997
Pubmed

Molecular cloning and characterization of mouse estradiol 17 beta-dehydrogenase (A-specific), a member of the aldoketoreductase family.

AKR1C1 AKR1C2 AKR1C3

2.03e-06520637737980
Pubmed

Thymic development beyond beta-selection requires phosphatidylinositol 3-kinase activation by CXCR4.

CXCR4 PIK3CD PIK3CG

2.03e-065206320038597
Pubmed

Preterm birth without progesterone withdrawal in 15-hydroxyprostaglandin dehydrogenase hypomorphic mice.

AKR1C1 AKR1C2 AKR1C3

2.03e-065206317872381
Pubmed

Mouse 3alpha-hydroxysteroid dehydrogenase mRNA: a marker of lung maturity.

AKR1C1 AKR1C2 AKR1C3

2.03e-065206317064890
Pubmed

Close kinship of human 20alpha-hydroxysteroid dehydrogenase gene with three aldo-keto reductase genes.

AKR1C1 AKR1C2 AKR1C3

2.03e-065206310672042
Pubmed

Pregnane X receptor (PXR) deficiency promotes hepatocarcinogenesis via induction of Akr1c18 expression and prostaglandin F2α (PGF2α) levels.

AKR1C1 AKR1C2 AKR1C3

2.03e-065206338788959
Pubmed

Down-regulation of neurosteroid biosynthesis in corticolimbic circuits mediates social isolation-induced behavior in mice.

AKR1C1 AKR1C2 AKR1C3

2.03e-065206318003893
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP34 MAP4 NOC2L ACLY NOL10 ANKHD1 OSBPL8 HERC2 CAP1 WDR36 UBR4 NOL11 IARS2 IGF2R WDR12 ZMYM3

2.04e-066532061622586326
Pubmed

HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.

CXCR4 PIK3CD PIK3CG PIK3R1

2.06e-0616206416524887
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

DENND4A ATP6AP1 PIK3R1 OSBPL9 OSBPL8 OSBPL11 PDZD8 FAM135A COG4 GPD2 SPG11 VPS13D IGF2R STEAP3

2.16e-065042061434432599
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TANC2 GON4L WDFY4 ANKH ANKRD36B ARID2 ANKRD36

2.48e-06101206710997877
Pubmed

Macrophage activation through CCR5- and CXCR4-mediated gp120-elicited signaling pathways.

CXCR4 PIK3CD PIK3CG PIK3R1

2.68e-0617206412960231
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

HIVEP1 VEZF1 ZMYM2 FSIP2 BBX ANLN HERC2 INO80 SRBD1 RLF ARID2 WDR12 CDC27 ZMYM3 ZNF292

3.96e-066082061536089195
Pubmed

Regulation of progesterone levels during pregnancy and parturition by signal transducer and activator of transcription 5 and 20alpha-hydroxysteroid dehydrogenase.

AKR1C1 AKR1C2 AKR1C3

4.04e-066206315471942
Pubmed

MEF2 and NR2F2 cooperate to regulate Akr1c14 gene expression in mouse MA-10 Leydig cells.

AKR1C1 AKR1C2 AKR1C3

4.04e-066206326748576
Pubmed

Orderly inactivation of the key checkpoint protein mitotic arrest deficient 2 (MAD2) during mitotic progression.

CDC16 BUB1B CDC27

4.04e-066206321335556
Pubmed

The Gαq/11-provoked induction of Akr1c18 in murine luteal cells is mediated by phospholipase C.

AKR1C1 AKR1C2 AKR1C3

4.04e-066206329107092
Pubmed

Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase.

AKR1C1 AKR1C2 AKR1C3

4.04e-066206315860270
Pubmed

Adrenal 20alpha-hydroxysteroid dehydrogenase in the mouse catabolizes progesterone and 11-deoxycorticosterone and is restricted to the X-zone.

AKR1C1 AKR1C2 AKR1C3

4.04e-066206317122075
Pubmed

Decidual prolactin silences the expression of genes detrimental to pregnancy.

AKR1C1 AKR1C2 AKR1C3

4.04e-066206317255200
Pubmed

Functional dynamics of H3K9 methylation during meiotic prophase progression.

AKR1C1 AKR1C2 KIT AKR1C3

4.32e-0619206417599069
Pubmed

Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways.

PIK3CG PIK3R1 SYK

7.04e-067206320167705
Pubmed

MicroRNA-200a serves a key role in the decline of progesterone receptor function leading to term and preterm labor.

AKR1C1 AKR1C2 AKR1C3

7.04e-067206322529366
Pubmed

A phosphodiesterase 11 (Pde11a) knockout mouse expressed functional but reduced Pde11a: Phenotype and impact on adrenocortical function.

AKR1C1 AKR1C2 AKR1C3

7.04e-067206333127481
Pubmed

A cluster of eight hydroxysteroid dehydrogenase genes belonging to the aldo-keto reductase supergene family on mouse chromosome 13.

AKR1C1 AKR1C2 AKR1C3

7.04e-067206312562828
Pubmed

The Steroidogenic Enzyme AKR1C3 Regulates Stability of the Ubiquitin Ligase Siah2 in Prostate Cancer Cells.

AKR1C1 AKR1C2 AKR1C3

7.04e-067206326160177
Pubmed

Aldo-ketoreductase 1c19 ablation does not affect insulin secretion in murine islets.

AKR1C1 AKR1C2 AKR1C3

7.04e-067206334843575
Pubmed

Genetic variation in the progesterone receptor and metabolism pathways and hormone therapy in relation to breast cancer risk.

AKR1C1 AKR1C2 AKR1C3

7.04e-067206319846565
Pubmed

17Beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: a novel role for androgen during the surge of surfactant.

AKR1C1 AKR1C2 AKR1C3

7.04e-067206316337335
Pubmed

LncRNAs-directed PTEN enzymatic switch governs epithelial-mesenchymal transition.

NOC2L NEDD1 ARMC2 RYR2 FBXL5 FSIP2 BBX CDC16

7.82e-06168206830631154
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

USP34 NRIP1 HIVEP1 RGPD1 ZMYM2 UNC45A ANKHD1 BUB1B NAV1 UBR4 RLF ZMYM3

8.41e-064182061234709266
Pubmed

Androgen Receptor Is Dispensable for X-Zone Regression in the Female Adrenal but Regulates Post-Partum Corticosterone Levels and Protects Cortex Integrity.

AKR1C1 AKR1C2 AKR1C3

1.12e-058206333584538
Pubmed

Cloning of mouse 17beta-hydroxysteroid dehydrogenase type 2, and analysing expression of the mRNAs for types 1, 2, 3, 4 and 5 in mouse embryos and adult tissues.

AKR1C1 AKR1C2 AKR1C3

1.12e-05820639224647
Pubmed

Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition.

AKR1C1 AKR1C2 AKR1B1 AKR1C3

1.37e-0525206426098214
Pubmed

Decrease in the T-box1 gene expression in embryonic brain and adult hippocampus of down syndrome mouse models.

AKR1C1 AKR1C2 AKR1C3

1.68e-059206333348080
Pubmed

Novel PI3K/Akt inhibitors screened by the cytoprotective function of human immunodeficiency virus type 1 Tat.

PIK3CD PIK3CG PIK3R1

1.68e-059206321765914
Pubmed

Mapping the Genetic Landscape of Human Cells.

ATP6AP1 NOC2L STXBP4 NOL10 RRM1 CDC16 BUB1B DNA2 WDR36 SLC7A1 CSTF3 CDC27

1.79e-054512061230033366
Pubmed

Fetal onset of aberrant gene expression relevant to pulmonary carcinogenesis in lung adenocarcinoma development induced by in utero arsenic exposure.

AKR1C1 AKR1C2 IGF2R AKR1C3

1.89e-0527206417077188
Pubmed

Identification of differentially expressed genes in mouse spermatogenesis.

AKR1C1 AKR1C2 ZNF836 AKR1C3

1.89e-0527206414581517
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

MAP4 ACLY UNC45A RRM1 BUB1B OSBPL8 PDZD8 FAM135A CAP1 GPD2 ANK3 IGF2R CTPS1 EIF2A CDC27

2.38e-057082061539231216
Pubmed

P110delta, a novel phosphoinositide 3-kinase in leukocytes.

PIK3CD PIK3CG PIK3R1

2.38e-051020639113989
Pubmed

Lack of placental neurosteroid alters cortical development and female somatosensory function.

AKR1C1 AKR1C2 AKR1C3

2.38e-0510206336313771
Pubmed

Extracellular human immunodeficiency virus type-1 Tat protein activates phosphatidylinositol 3-kinase in PC12 neuronal cells.

PIK3CD PIK3CG PIK3R1

2.38e-051020638798481
Pubmed

The APC/C maintains the spindle assembly checkpoint by targeting Cdc20 for destruction.

CDC16 BUB1B CDC27

2.38e-0510206318997788
Pubmed

Expression of HIV-1 nef decreases basal phosphatidyl-inositol 3-kinase activity.

PIK3CD PIK3CG PIK3R1

2.38e-051020639247029
Pubmed

The HIV-1 nef protein interferes with phosphatidylinositol 3-kinase activation 1.

PIK3CD PIK3CG PIK3R1

2.38e-051020638636073
Pubmed

Stable MCC binding to the APC/C is required for a functional spindle assembly checkpoint.

CDC16 BUB1B CDC27

2.38e-0510206324464857
Pubmed

Nek2A destruction marks APC/C activation at the prophase-to-prometaphase transition by spindle-checkpoint-restricted Cdc20.

CDC16 BUB1B CDC27

2.38e-0510206325673878
Pubmed

A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.

NOL10 RRM1 ANLN BUB1B OSBPL9 OSBPL8 WDR36 SRBD1 IGF2R ARID2 CSTF3 STEAP3

2.79e-054722061238943005
Pubmed

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

CTTNBP2 GON4L CHN1 CDC16 OSBPL9 NAV3 WDR36 RLF IARS2 CDC27

3.12e-053312061019490893
Cytoband10p15-p14

AKR1C1 AKR1C2 AKR1C3

1.76e-066206310p15-p14
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF717 HIVEP1 VEZF1 ZNF268 ZNF177 ZNF440 ZNF836 ZNF117 ZNF433 ZFP62 ZNF211 RLF ZNF26 ZNF425 ZNF728 ZNF816 ZNF69 ZNF639 ZNF292

3.91e-067181431928
GeneFamilyAldo-keto reductases

AKR1C1 AKR1C2 AKR1B1 AKR1C3

4.79e-06151434399
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL9 OSBPL8 OSBPL11

1.01e-04121433670
GeneFamilyZinc fingers MYM-type

ZMYM2 ZMYM3

9.13e-046143286
GeneFamilyNLR family

NLRP11 NLRC4 NLRP8

9.81e-04251433666
GeneFamilySH2 domain containing

CHN1 PIK3R1 SYK SHE TNS4

1.24e-031011435741
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGEF16 ANLN OSBPL9 OSBPL8 OSBPL11 PHLPP1 PHLPP2

1.27e-032061437682
GeneFamilyPhosphatidylinositol 3-kinase subunits

PIK3CD PIK3CG

1.69e-0381432831
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

TANC2 RGPD1 TMTC2 CDC16 CDC27

2.21e-031151435769
GeneFamilyWD repeat domain containing

NEDD1 PLAA NWD1 WDR36 WDFY4 WDHD1 WDR12

4.88e-032621437362
GeneFamilyAnaphase promoting complex |Tetratricopeptide repeat domain containing

CDC16 CDC27

5.31e-03141432402
CoexpressionIRITANI_MAD1_TARGETS_UP

AKR1C1 AKR1C2 PIK3R1 AKR1C3

7.68e-06172034MM826
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

USP34 NRIP1 HIVEP1 VEZF1 ZMYM2 BBX CDC16 BUB1B NAV3 OSBPL8 PHLPP1 SPG11 ADGRG6 RLF SLC7A1 IGF2R WDHD1 CDC27 PHLPP2 ZNF292

1.22e-0585620320M4500
CoexpressionGSE3039_B2_VS_B1_BCELL_UP

NRIP1 DENND4A TLR8 BBX PHLPP1 ALAS2 KLRC1 FKBP7 PHLPP2

2.66e-051992039M6450
CoexpressionGSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_60H_DN

ACLY ANK3 INTS7 ANKH SLC7A1 WDHD1 SEL1L2 CTPS1 ZNF292

2.76e-052002039M9657
CoexpressionGSE3982_DC_VS_NEUTROPHIL_UP

SPINT1 NOC2L SQLE RRM1 PLXNB2 AKR1B1 INTS7 NOL11 CSTF3

2.76e-052002039M5461
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

TANC2 ZNF717 SMG1 DENND4A MCMDC2 FBXL5 PHKA1 PLAA ANLN GMDS DNA2 KIT FAM135A WDR36 SRBD1 CINP USP26 RANBP17 M1AP IARS2 WDHD1 CTPS1

8.90e-0682019822gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
ToppCellControl-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

TANC2 NRIP1 AKR1C1 AKR1C2 OSBPL11 AKR1B1 GPD2 SLC7A7 LGALS3BP AKR1C3

1.64e-081852061085cb81759589a26d83676cffbf2bc37399683c10
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

USP34 SMG1 PIK3R1 ANK3 TRIM73 RTTN ABCA5 ANKRD36 MCTP2 ZNF292

3.27e-0819920610f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

CDC16 MRC1 TASL RLF TIMP3 AKR1C3 MCTP2

3.58e-0870206737e34ef782b253c43628d5bb2fe5e0294573d0ef
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPINT1 SPEG RRM1 ANLN GMDS DNA2 MRC1 KCNH4 LONRF3

1.53e-071782069de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TANC2 SMG1 ANK3 TRIM73 RTTN ABCA5 ANKRD36 MCTP2 ZNF292

3.62e-071972069e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellTCGA-Skin-Metastatic-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

USP34 DENND4A TLR8 NLRC4 BBX CXCR4 PIK3CG SLC7A7 TASL

3.77e-071982069af4fb9eb2295c7b90624b38ba25619aa15254efa
ToppCellSigmoid-B_cell-B_cell_IgG_Plasma|B_cell / Region, Cell class and subclass

CTTNBP2 ATP8A2 ANKHD1 PLAA KIT SLC7A7 TASL TIMP3 ANKRD36

3.77e-071982069305d7ae9b070ac7211638a5282374c02bf13af40
ToppCellTCGA-Skin-Metastatic|TCGA-Skin / Sample_Type by Project: Shred V9

USP34 DENND4A TLR8 NLRC4 BBX CXCR4 PIK3CG SLC7A7 TASL

3.77e-071982069ad39cce004867f083f8da1954e0cf5a263815184
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

USP34 DENND4A TLR8 NLRC4 BBX CXCR4 PIK3CG SLC7A7 TASL

3.77e-07198206962cbf4b29e8af4983fb47a17f96da62682a5137e
ToppCellfacs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPINT1 JAML SYK MRC1 TASL WDFY4 ANKH TNS4

1.05e-0616520682477b0f1a0ea26184cf3cc4a9ffcdfa825cbc615
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Diffuse-3|TCGA-Stomach / Sample_Type by Project: Shred V9

JAML PIK3CG NAV3 SHE TASL WDFY4 MILR1 HMCN1

1.14e-061672068d2230c894ccf9dbba9196e079ae81f384d43da63
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

JAML CC2D2B NAV1 KIT MRC1 TASL WDFY4 MTURN

1.20e-061682068d60f7cd8269f373827f49c7785002cb38e4570a9
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

JAML CC2D2B NAV1 KIT MRC1 TASL WDFY4 MTURN

1.25e-061692068ccd98f9005aa0a88bd49f153be4e7200cc3dd0ac
ToppCellPCW_13-14-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CXCR4 PIK3CD PIK3CG SYK TASL TERT WDFY4 MILR1

2.46e-0618520688fc357ee041bfd588986730a52ea2021b5f88941
ToppCellPCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_B-im_lymphoid_progenitor_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

JAML PIK3CD PIK3CG KLRC1 MRC1 TASL WDFY4 MILR1

2.46e-0618520685ec2c3ae5c477645241e8eaf19d222562e1f7ed6
ToppCellIPF-Myeloid-Macrophage_Alveolar|IPF / Disease state, Lineage and Cell class

TANC2 JAML OSBPL11 AKR1B1 MRC1 SLC7A7 LGALS3BP AKR1C3

3.00e-061902068e539ebc0f4c5ee5dba86c614387be7d91338ad47
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF440 PHLPP1 GMDS CNGA1 VWA5B1 ANK3 ADGRG6 TNS4

3.37e-061932068a5695ce2e24a62026ae28f3dea07ca4a435206b8
ToppCellMacrophages-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

NRIP1 JAML AKR1C2 AKR1B1 MRC1 SLC7A7 LGALS3BP AKR1C3

3.64e-0619520682af46e87947c16a7c2c367637e606cfbb8a78528
ToppCellSmart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-T_lymphocytic-T_cell|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ZNF831 JAML CXCR4 PIK3R1 KLRC1 ANK3 ANKRD36 ZNF292

3.78e-0619620684a880a5d2c7047c050c7d6dd62186f35dc5c01f7
ToppCell11.5-Airway-Immune-Hematopoietic,_Macrophage|Airway / Age, Tissue, Lineage and Cell class

JAML NLRC4 SYK MRC1 SLC7A7 TASL WDFY4 MILR1

3.78e-061962068f73573b5d9c735f2a2c718472b7d12b10f2a3718
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alv_dividing|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ORC6 NCAPH2 ANLN SYK DNA2 MRC1 WDFY4 WDHD1

3.92e-061972068d669d90c3f9e98b41bcbc49dbdc5698e0b42597c
ToppCellIPF-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

TANC2 TMTC2 RYR2 OSBPL8 COL15A1 ANK3 HMCN1 MCTP2

3.92e-061972068f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

JAML NLRC4 SAMD9L SYK OSBPL11 MRC1 SLC7A7 WDFY4

4.07e-061982068e125eb8aa57c172e5518874da1bd25998292f5e2
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_alveolar-Macro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

JAML NLRC4 SAMD9L SYK OSBPL11 MRC1 SLC7A7 WDFY4

4.07e-0619820680baeb8e2c199ff10bb5c829c523546af3c9227c1
ToppCellTracheal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

AKR1C2 ZNF836 PLAA TRIM73 NTRK2 ZNF26 ARID2

4.09e-0614020670e1e9281de87df178ac41ed6b697b4fa09be2749
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.6.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TANC2 NRIP1 SYK OSBPL11 AKR1B1 MRC1 LGALS3BP LONRF3

4.22e-061992068fde8e3ba19d19069a4d3b8db55bfe6220cf634d5
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

TANC2 BBX PIK3R1 OSBPL8 KIT CCDC68 ANKRD36 ZNF292

4.22e-061992068c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macrophage_intermediate|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

JAML PIK3CG SYK TRIM74 MRC1 SLC7A7 WDFY4 MILR1

4.22e-06199206854167894a16e975d0541cbe3e515bcfa183044f6
ToppCellPND01-Immune-Immune_Myeloid-DC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCMDC2 JAML PIK3CG DNA2 SLC7A7 WDFY4 MILR1

7.03e-061522067c8faa83dcaddb2ce2bb890f90dd8e676f7dcb1b3
ToppCellPND01-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCMDC2 JAML PIK3CG DNA2 SLC7A7 WDFY4 MILR1

7.03e-061522067c3f00beb8b6fde99263d5ed6bbe3c2415d02f91d
ToppCellPND01-Immune-Immune_Myeloid-DC-cDC2|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

MCMDC2 JAML PIK3CG DNA2 SLC7A7 WDFY4 MILR1

7.03e-061522067cefc0ab592e99badf145fb95adf9906cb81be81c
ToppCellE16.5-samps-Myeloid-Fetal_macrophage|E16.5-samps / Age Group, Lineage, Cell class and subclass

TLR8 PIK3CD PIK3CG MRC1 TASL WDFY4 MILR1

7.34e-061532067e9567966fe4426176e2f2dc0be4832c769c9903a
ToppCellPosterior_cortex-Hematopoietic-MACROPHAGE|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ITGAE TLR8 NLRC4 PIK3CG WDFY4 MILR1

8.00e-06102206657ad3d48adeb41f6ab65883e61d3b1e74a94ad1a
ToppCellPosterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ITGAE TLR8 NLRC4 PIK3CG WDFY4 MILR1

8.00e-0610220669392288e284b71f3a208d9f283e6e3c944b7dd10
ToppCellPosterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ITGAE TLR8 NLRC4 PIK3CG WDFY4 MILR1

8.00e-0610220660ec549ee94da5f2d7275490e90d816c645f6d4fc
ToppCellPosterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)--|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ITGAE TLR8 NLRC4 PIK3CG WDFY4 MILR1

8.00e-06102206630fa92383898f370dabc41dd23d6907f14ba1a06
ToppCellPosterior_cortex-Hematopoietic-MACROPHAGE-MP1(C1qb)-MACROPHAGE_Macrophage.C1qb.Mrc1_(Resident_macrophage)-|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ITGAE TLR8 NLRC4 PIK3CG WDFY4 MILR1

8.00e-061022066c58e09aaa11b664c7d99e91f903561fa18460f05
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ELAPOR2 CTTNBP2 SPEG CC2D2B ZNF433 NTRK2 HMCN1

9.43e-0615920677cda111bb98f1241989e49d490bdf51a712ea589
ToppCellfacs-Aorta-Heart-24m-Myeloid-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL10 JAML PIK3CD DNA2 WDFY4 MILR1 WDHD1

1.30e-051672067b85fd7ab21c80470bca804c788ce49a2bce763f8
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

ORC6 RRM1 BDKRB2 BUB1B DNA2 WDHD1 PHLPP2

1.40e-051692067a949f547b53126a208819bade74a1ac9b2a36ea7
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

ORC6 RRM1 BDKRB2 BUB1B DNA2 WDHD1 PHLPP2

1.40e-051692067195d5cd60d646ac6d40a3321b2f739917e7aef14
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|Myeloid_cells / Location, Cell class and cell subclass

STXBP4 FSIP2 BUB1B ANK3 NTRK2 ANKRD36 ZNF639

1.40e-051692067bea8aba1f3cc3d0e8d448c1c45f5354d26ebf850
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ZNF831 ANLN PIK3CD BUB1B TASL WDFY4 MILR1

1.51e-05171206755c7bf7211587fa08df13c0a4ff5b78a85d5439e
ToppCellfacs-Trachea-nan-3m-Myeloid-macrophage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TLR8 CXCR4 PIK3CG SYK MRC1 TASL WDFY4

1.63e-0517320674e9b6c71030ae0d63d54e7255e4a10b25970fcc4
ToppCellnormal_Lung-T/NK_cells-Exhausted_Tfh|normal_Lung / Location, Cell class and cell subclass

GTPBP6 ITGAE CHN1 RYR2 DNA2 NTRK2 TNS4

1.63e-051732067e8ead6c51c41dbd43c717ba9d1a7a0ab39c79330
ToppCellLV-17._Lymphocyte|World / Chamber and Cluster_Paper

ZNF831 JAML CXCR4 PIK3CD KIT KLRC1 MCTP2

1.63e-051732067212f013ff761cbab24a537071739867c08c402a4
ToppCellControl-Lymphoid-ILC_B|World / Disease state, Lineage and Cell class

DENND4A CXCR4 PIK3CD KIT KLRC1 CEACAM16 MCTP2

1.82e-05176206757ad9c9f5fda6bc24695587ed14190514fd8d96a
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

TANC2 STXBP4 PLXNB2 FSIP2 BUB1B NTRK2 CDC27

1.82e-0517620677a74217b7fa1032b918f00a3972dff5fab74671a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC2 SYK KIT CNGA1 VWA5B1 ANK3 ELF5

1.89e-051772067f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCelldroplet-Skin-nan-18m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A ITGAE ZNF831 JAML PIK3CD LGALS3BP CRTAM

1.96e-051782067e0769ad06f92423a3cb6c78a61da3ba5bd9b4eae
ToppCelldroplet-Skin-nan-18m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A ITGAE ZNF831 JAML PIK3CD LGALS3BP CRTAM

1.96e-05178206712d5c6be6cfbf733e3cb02780606b3725eda7d2b
ToppCellLA-17._Lymphocyte|World / Chamber and Cluster_Paper

JAML CXCR4 PIK3CD PIK3CG ALAS2 KIT MCTP2

1.96e-05178206734ec499d03cc198cfefa19a724d4c81974052f65
ToppCelldroplet-Skin-nan-18m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A ITGAE ZNF831 JAML PIK3CD LGALS3BP CRTAM

1.96e-05178206711c2ce093b7538518c8d4497dc5b0b4da22bf1a8
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYK AKR1B1 MRC1 SLC7A7 TASL WDFY4 LONRF3

2.03e-051792067330c1326ba93bb8f32559ee1cc40e357cc44ad8d
ToppCellLPS_only-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYK AKR1B1 MRC1 SLC7A7 TASL WDFY4 LONRF3

2.03e-051792067dc03b9045510eb1bb934329646bb92dd06890ce9
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

AKR1C1 SLC9C1 NAV1 AKR1B1 CNGA1 ELF5 MCTP2

2.11e-05180206749829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCellRSV-Healthy-0|RSV / Virus stimulation, Condition and Cluster

USP34 ORC6 CHN1 SAMD9L PHLPP1 AKR1B1 AKR1C3

2.11e-051802067974044056e2f7e909cb11c6f6ca89e58bf95f7e5
ToppCellRSV-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

USP34 ORC6 CHN1 SAMD9L PHLPP1 AKR1B1 AKR1C3

2.11e-051802067703a1d0f9536af94d56757eb01221878d7b7fe61
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_B-im_B_cell_(15)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CXCR4 PIK3CD PIK3CG SYK TASL WDFY4 MILR1

2.18e-05181206751e4d6bfdbf414d8e30aee2e6f7492f4f7f54373
ToppCellLV-17._Lymphocyte|LV / Chamber and Cluster_Paper

ZNF831 JAML CXCR4 PIK3CD KIT KLRC1 MCTP2

2.18e-05181206781fafa69c8c240250a667a5f3b321e8be1b9a288
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

USP34 SMG1 TRIM74 ANK3 ANKRD36B ARID2 ANKRD36

2.18e-051812067f2315414e714ac86211546a935660c4be6e85f1b
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 TMTC2 SYK CNGA1 ANK3 GRAMD2B ELF5

2.34e-051832067b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellPCW_05-06-Immune_Lymphocytic-Immune_Lymphocytic_B|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

JAML PIK3CG KLRC1 MRC1 TASL WDFY4 MILR1

2.34e-051832067ffa7f2b2929ea4bd53f3f1ae23bd27f8bb4aac47
ToppCellIPF-Lymphoid-ILC_A|IPF / Disease state, Lineage and Cell class

DENND4A CXCR4 PIK3R1 KIT KLRC1 CRTAM MCTP2

2.34e-05183206749bfeaae13eb236f61a5486ee75c39789936bb8a
ToppCellmild_COVID-19_(asymptomatic)-T/NK_proliferative|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ORC6 RGPD1 RRM1 ANLN BUB1B DNA2 KLRC1

2.34e-051832067df8568751205313d149939ea2683097e3652a60b
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRM1 ANLN BUB1B GMDS MRC1 WDHD1 LONRF3

2.34e-05183206742dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCellILEUM-inflamed-(1)_T_cell-(1)_CD8_Trm|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

SMG1 MAP4 JAML CXCR4 PIK3R1 KLRC1 CRTAM

2.43e-051842067cef3ee2a4a0af961aa3b4c92150d423e841ae8c1
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ORC6 BDKRB2 BUB1B ZNF724 DNA2 WDHD1 PHLPP2

2.43e-0518420676b2449ac65a2322aa0479fba0d89828f243aabbe
ToppCell343B-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ORC6 BDKRB2 BUB1B ZNF724 DNA2 WDHD1 PHLPP2

2.43e-051842067e90622b82fa7f16a1faaf7a4724c958f2d83341d
ToppCellPCW_10-12-Immune_Lymphocytic-Immune_Lymphocytic_NK/ILC-im_ILC3_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ZNF831 JAML CXCR4 KIT KLRC1 NTRK2 GRAMD2B

2.43e-0518420673e9d75af578297950e469f23fb2d28393a2feef8
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

PIK3CG NAV3 OSBPL8 KIT NTRK2 HMCN1 ZNF728

2.43e-05184206767164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCellCOVID_vent-Myeloid-Dendritic|COVID_vent / Disease condition, Lineage, Cell class and subclass

JAML SYK NAV1 MRC1 WDFY4 ADGRG6 STEAP3

2.60e-05186206763a5cdd3f60681762a218be32db84be8f29b88fd
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGAP42 STXBP4 TBC1D2B CHN1 RYR2 ADGRG6 CCDC68

2.60e-051862067888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellCOVID_vent-Myeloid-Dendritic-cDC|COVID_vent / Disease condition, Lineage, Cell class and subclass

JAML SYK NAV1 MRC1 WDFY4 ADGRG6 STEAP3

2.60e-05186206739457a7b43537f2c3e221f9375c95d4515424d7d
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TANC2 SLC9C1 FAM135A ANK3 RANBP17 CTPS1 MCTP2

2.60e-051862067acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

ARHGAP42 USP34 SMG1 OSBPL11 VPS13D HMCN1 ARID2

2.60e-05186206703db813598b67b1e08f759758a1c2023396921fa
ToppCellCOVID_non-vent-Myeloid-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

JAML SYK NAV1 KIT MRC1 WDFY4 ADGRG6

2.69e-051872067936aaca144b79a809617cbe3058bf434a4b3d46a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TMTC2 SYK KIT CNGA1 VWA5B1 ANK3 ELF5

2.69e-0518720672d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCellCOVID_non-vent-Myeloid-Dendritic-cDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

JAML SYK NAV1 KIT MRC1 WDFY4 ADGRG6

2.69e-05187206755fe4e8b4f301876716c1af15c34d42164f2358e
ToppCellP15-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TANC2 DENND4A KLK10 CXCR4 SHE ADGRG6 TIMP3

2.78e-05188206750b27fc12347ca16bd62333baf345c83cb422a8f
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

RHOJ CHN1 NAV3 SHE KIT NTRK2 TIMP3

2.78e-051882067117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 TMTC2 SYK CNGA1 ANK3 SLC7A1 ELF5

2.78e-051882067e30a4ddac0da8cdcf621d98e28e3895cd9307e7a
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

USP34 SMG1 DENND4A RLF IGF2R ARID2 ANKRD36

2.78e-051882067ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CTTNBP2 CXCR4 NAV1 SHE AKR1B1 FAM135A HMCN1

2.88e-051892067c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPAS3 TMTC2 SYK CNGA1 ANK3 SLC7A1 ELF5

2.88e-051892067fc88c51ace7d883c01617f3f9b5fab70cc91cc09
ToppCellCOVID_vent-Myeloid-Monocytic-SC_&_Eosinophil|COVID_vent / Disease condition, Lineage, Cell class and subclass

NRIP1 PDZD8 KIT ADGRG6 TIMP3 AKR1C3 MTURN

2.88e-0518920672157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC9C1 SYK KIT CNGA1 VWA5B1 ANK3 ELF5

2.88e-051892067532aaf02b364c5c4f58a2021c7c21d86df3875c9
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHOJ AKR1C1 AKR1C2 SHE SLC7A1 TIMP3 AKR1C3

2.98e-05190206732400c62cb9de4c2b24af4206c21a0215ab12212
ToppCell3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RHOJ AKR1C1 AKR1C2 SHE SLC7A1 TIMP3 AKR1C3

2.98e-051902067b2bd2cb384bb8a5662064ed1aee68e905e1f780d
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

JAML PIK3CD PIK3CG MRC1 TASL WDFY4 MILR1

2.98e-051902067773c55b9e28c2f77a5eb5f0adb0fa9862fb9611d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TANC2 TMTC2 SYK CNGA1 ANK3 SLC7A1 ELF5

2.98e-05190206711d3c31167ea71809b4cc3757a0c6ea54a448602
ToppCellIPF-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

TANC2 JAML AKR1C2 OSBPL11 AKR1B1 LGALS3BP AKR1C3

2.98e-0519020672592765016f291565697265800a232b2edef3792
ToppCellCOVID-19-Heart-EC_3|Heart / Disease (COVID-19 only), tissue and cell type

RHOJ TMTC2 CHN1 CC2D2B GMDS SHE ADGRG6

2.98e-05190206778e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

ORC6 RRM1 ANLN BUB1B DNA2 RTTN WDHD1

2.98e-051902067e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

KLK10 SPINT1 AKR1C1 BDKRB2 ANK3 GRAMD2B TNS4

2.98e-05190206751ca9ef4df3220487152fcf684147730637c7cc1
ToppCellAdult-Immune-monocyte-D175|Adult / Lineage, Cell type, age group and donor

JAML PIK3CD SYK NAV1 SLC7A7 TASL WDFY4

3.08e-051912067cbebb4d9550fdcd606cb3685ac9546c6b73fd422
ToppCell5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TANC2 ATP8A2 TBC1D2B ANLN PIK3CG KIT ADGRG6

3.08e-05191206754f07e4de61735051498846afb44b1798bed8144
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 ACLY SQLE NTRK2 ANKH GRAMD2B PITPNM3

3.08e-051912067f76f3f5c7902a3659d8cbe470f96ce57c8a6744d
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ELAPOR2 ACLY SQLE FAM135A NTRK2 ANKH PITPNM3

3.18e-0519220675b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

ANLN PIK3CD BUB1B SYK MRC1 DNAAF9 WDFY4

3.18e-051922067a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
Drug4-hydroxyequilenin-o-quinone

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.06e-0772024ctd:C117714
Drugcyclopentanol

AKR1C1 AKR1C2 AKR1C3

6.88e-0732023ctd:C016327
Drugcyclopentanone

AKR1C1 AKR1C2 AKR1C3

6.88e-0732023ctd:C007201
Drug4-benzoylbenzoic acid

AKR1C1 AKR1C2 AKR1C3

6.88e-0732023ctd:C058818
Drugdichloro(4-cymene)ruthenium(II)

AKR1C1 AKR1C2 AKR1C3

6.88e-0732023ctd:C530610
Drugbenzene dihydrodiol

ATP6AP1 AKR1C1 AKR1C2 AKR1B1 AKR1C3

1.22e-06222025CID000000418
DrugDihydroxydihydrobenzopyrenes

AKR1C1 AKR1C2 AKR1B1 AKR1C3

1.89e-06112024ctd:D004101
Drugchlordecone alcohol

AKR1C1 AKR1C2 AKR1B1 AKR1C3

1.89e-06112024CID000013946
Drugcloxazolam

AKR1C1 AKR1C2 AKR1C3

2.73e-0642023ctd:C005522
DrugPregnanes

AKR1C1 AKR1C2 AKR1C3

2.73e-0642023ctd:D011278
Drugtetralol

AKR1C1 AKR1C2 AKR1C3

2.73e-0642023ctd:C019106
Druggliquidone

AKR1C1 AKR1C2 AKR1C3

2.73e-0642023ctd:C010969
Drug3',3'',5',5''-tetrabromophenolphthalein

AKR1C1 AKR1C2 AKR1C3

2.73e-0642023ctd:C018156
Drug1-acenaphthenol

AKR1C1 AKR1C2 AKR1B1 AKR1C3

5.62e-06142024CID000022750
DrugHydroxysteroids

AKR1C1 AKR1C2 AKR1C3

6.79e-0652023ctd:D006914
DrugNSC86000

AKR1C1 AKR1C2 AKR1C3

6.79e-0652023CID000257630
Drugcresolphthalein

AKR1C1 AKR1C2 AKR1C3

6.79e-0652023ctd:C010092
DrugEstazolam

AKR1C1 AKR1C2 AKR1C3

1.35e-0562023ctd:D004949
DrugGlipizide

AKR1C1 AKR1C2 AKR1C3

1.35e-0562023ctd:D005913
Drugacenaphthene-1-ol

AKR1C1 AKR1C2 AKR1C3

1.35e-0562023ctd:C023723
DrugMedazepam

AKR1C1 AKR1C2 AKR1C3

1.35e-0562023ctd:D008472
Drugduocarmycin

NLRP11 ATP6AP1 CHN1

2.35e-0572023CID000115369
Drugzomepirac

AKR1C1 AKR1C2 AKR1C3

2.35e-0572023ctd:C020549
Drugbenzo(a)pyrene-7,8-dione

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.61e-05202024ctd:C076588
DrugChrysenes

AKR1C1 AKR1C2 AKR1B1 AKR1C3

2.61e-05202024ctd:D002911
Drugindanone

ATP6AP1 AKR1C1 AKR1C2 AKR1B1 AKR1C3

3.02e-05412025CID000006735
DrugNitrazepam

AKR1C1 AKR1C2 AKR1C3

3.73e-0582023ctd:D009567
DrugSulfaphenazole [526-08-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A

NRIP1 MAP4 SQLE ZMYM2 BBX PIK3R1 SLC7A1 CDC27 ZNF292

4.27e-0518520291673_DN
Drug2'-Monophosphoadenosine 5'-Diphosphoribose

AKR1C1 AKR1C2 AKR1B1 AKR1C3

4.67e-05232024DB03461
Drug4-hydroxybenzoic acid

AKR1C1 AKR1C2 AKR1C3

5.56e-0592023ctd:C038193
Drug20-alpha-Dihydroprogesterone

AKR1C1 AKR1C2 AKR1C3

5.56e-0592023ctd:D004092
Drug9,10-phenanthrenequinone

AKR1C1 AKR1C2 AKR1B1 AKR1C3

6.57e-05252024ctd:C005399
Drugalpha-methylcinnamic acid

AKR1C1 AKR1C3

7.83e-0522022ctd:C510582
Drug(10ALPHA,13ALPHA,14BETA,17ALPHA)-17-HYDROXYANDROST-4-EN-3-ONE

AKR1C1 AKR1C2

7.83e-0522022DB07768
Drugbaccharin

AKR1C2 AKR1C3

7.83e-0522022ctd:C012764
Drug2-((9H-PURIN-6-YLTHIO)METHYL)-5-CHLORO-3-(2-METHOXYPHENYL)QUINAZOLIN-4(3H)-ONE

PIK3CD PIK3CG

7.83e-0522022DB06831
Drugoctyl gallate

AKR1C1 AKR1C2 AKR1C3

7.89e-05102023ctd:C016627
Drugbis(tri-n-butyltin)oxide

ORC6 ACLY RRM1 AKR1C2 CXCR4 PIK3CD PIK3CG BUB1B SYK GPD2 TMEM254 IGF2R ABCA5 FKBP7 EIF2A

9.81e-0553820215ctd:C005961
DiseaseNeoplasms, Hormone-Dependent

AKR1C1 AKR1C2 AKR1C3

3.02e-0731993C0027661
DiseaseHermaphroditism

AKR1C1 AKR1C2 AKR1C3

2.99e-0651993C0019269
DiseaseAmbiguous Genitalia

AKR1C1 AKR1C2 AKR1C3

2.99e-0651993C0266362
DiseasePseudohermaphroditism

AKR1C1 AKR1C2 AKR1C3

2.99e-0651993C0033804
DiseaseIntersex Conditions

AKR1C1 AKR1C2 AKR1C3

2.99e-0651993C2930618
DiseaseSex Differentiation Disorders

AKR1C1 AKR1C2 AKR1C3

2.99e-0651993C2930619
DiseaseDisorders of Sex Development

AKR1C1 AKR1C2 AKR1C3

1.04e-0571993C0036875
Diseaselanguage measurement

ATP8A2 GON4L RRM1 GMDS ANK3 TMEM254 KCNH4

3.64e-051341997EFO_0007797
DiseaseObesity, Hyperphagia, and Developmental Delay

AKR1C2 NTRK2

4.53e-0521992C3151303
Diseaselaryngeal squamous cell carcinoma, hypopharynx cancer

AKR1C1 RTTN

4.53e-0521992EFO_0006352, EFO_0007321
DiseaseActivated PI3K-delta syndrome

PIK3CD PIK3R1

4.53e-0521992cv:CN295305
Diseasealcohol and nicotine codependence

HIVEP1 RGPD1 CAPN7

8.22e-05131993EFO_0004776
DiseaseACTIVATED PI3K-DELTA SYNDROME

PIK3CD PIK3R1

1.35e-0431992C3714976
Diseaseresponse to methotrexate

AKR1C1 AKR1C2 LINS1

1.59e-04161993GO_0031427
Diseaseprimary immunodeficiency disease (is_implicated_in)

TLR8 PIK3CG SYK DPP9

1.84e-04421994DOID:612 (is_implicated_in)
DiseaseAntihypertensive use measurement

ARHGAP42 ZNF831 PIK3R1 GMDS AKR1B1 INO80 SRBD1 SLC7A1

4.61e-042651998EFO_0009927
DiseaseEndometrial Neoplasms

NRIP1 AKR1C1 AKR1B1 AKR1C3

6.41e-04581994C0014170
Diseaseleiomyosarcoma (is_marker_for)

KIT TERT

6.67e-0461992DOID:1967 (is_marker_for)
Diseasecortolone glucuronide (1) measurement

AKR1C2 AKR1C3

6.67e-0461992EFO_0800552
DiseaseAlcohol Related Birth Defect

ANK3 NTRK2

6.67e-0461992C3146244
DiseaseLiver carcinoma

ACLY RRM1 AKR1C2 ADRA1A ANLN BUB1B COL15A1 TERT IGF2R ARID2 PITPNM3

7.02e-0450719911C2239176
Diseasecardiovascular disease

ARHGAP42 USP34 ZNF268 EFCAB13 ZNF831 PIK3R1 NAV1 GMDS AKR1B1 SLC7A1

1.15e-0345719910EFO_0000319
Diseaseproteoglycan 3 measurement

USP34 AIFM2

1.23e-0381992EFO_0802970
DiseaseEndometrial Carcinoma

NRIP1 AKR1C1 AKR1B1 AKR1C3

1.44e-03721994C0476089
Diseaseplexin-B2 measurement

PLXNB2 MRC1

1.58e-0391992EFO_0021867
Diseasemalignant epithelial tumor of ovary

COL15A1 TERT AKR1C3

1.69e-03351993MONDO_0018364
DiseaseCorneal astigmatism

BDKRB2 KCNU1 PIK3R1 HERC2

1.85e-03771994EFO_1002040
Diseasebreast cancer, ovarian carcinoma

NRIP1 STXBP4 TERT

1.98e-03371993EFO_0001075, MONDO_0007254
Diseaseductal carcinoma in situ (is_marker_for)

KLK10 TERT AKR1C3

2.31e-03391993DOID:0060074 (is_marker_for)
DiseaseT-cell acute lymphoblastic leukemia (is_implicated_in)

CXCR4 AKR1C3

2.39e-03111992DOID:5603 (is_implicated_in)
Diseasegastrointestinal stromal tumor (is_implicated_in)

KIT TERT

2.39e-03111992DOID:9253 (is_implicated_in)
Diseasecampesterol measurement

PIK3R1 SLC7A7

2.39e-03111992EFO_0020008
Diseasebeverage consumption measurement

HIVEP1 RYR2 INTS7 NTRK2

2.43e-03831994EFO_0010088
DiseaseNeoplastic Cell Transformation

AKR1C1 AKR1C2 CXCR4 PHLPP1 AKR1C3

2.57e-031391995C0007621
DiseaseMalignant neoplasm of breast

NRIP1 KLK10 STXBP4 EFCAB13 GPR180 ADRA1A CXCR4 OSBPL11 HERC2 KIT NLRP8 UBR4 SLC7A7 TERT LONRF3 CDC27

2.65e-03107419916C0006142
DiseaseMyeloproliferative disease

ZMYM2 TERT

2.86e-03121992C0027022
Diseaseprostate carcinoma

TANC2 NRIP1 TMTC2 NOL10 ARMC2 BBX ANLN SYK GMDS AKR1B1 TERT ANKH ANKRD36 PHLPP2

3.03e-0389119914EFO_0001663
DiseaseProstatic Neoplasms

PIK3CD PIK3R1 COL15A1 TERT SLC7A1 IGF2R ARID2 AKR1C3 CDC27 ZMYM3 ZNF292

3.24e-0361619911C0033578
DiseaseMalignant neoplasm of prostate

PIK3CD PIK3R1 COL15A1 TERT SLC7A1 IGF2R ARID2 AKR1C3 CDC27 ZMYM3 ZNF292

3.24e-0361619911C0376358
DiseaseCalcium channel blocker use measurement

ARHGAP42 USP34 MAP4 ZNF831 AKR1B1 SLC7A1

3.33e-032131996EFO_0009930
Diseasekynurenic acid measurement

ZNF177 SLC7A7

3.36e-03131992EFO_0010506
Diseasemale infertility (implicated_via_orthology)

ARMC2 KIT

3.36e-03131992DOID:12336 (implicated_via_orthology)
DiseaseHamman-Rich syndrome

TERT DPP9

3.90e-03141992C0085786
Diseaseglaucoma

CTTNBP2 GMDS HERC2 SRBD1 ANKH

3.99e-031541995MONDO_0005041
Diseaseprostate cancer (is_marker_for)

PIK3R1 PHLPP1 TERT TIMP3 AKR1C3

4.21e-031561995DOID:10283 (is_marker_for)
Diseasenon-dense area measurement, mammographic density measurement

RGPD1 KCNU1

4.49e-03151992EFO_0005941, EFO_0006504
DiseaseEndometrioma

AKR1C1 AKR1C2 AKR1B1 ANKH AKR1C3

4.81e-031611995C0269102
DiseaseEndometriosis

AKR1C1 AKR1C2 AKR1B1 ANKH AKR1C3

4.81e-031611995C0014175
Diseaseneurotic disorder

HIVEP1 CTTNBP2 BBX CCDC68

4.93e-031011994EFO_0004257
DiseaseWeight Gain

MAP4 AKR1C2 OSBPL8 VPS13D

5.10e-031021994C0043094
DiseaseMalignant lymphoma, lymphocytic, intermediate differentiation, diffuse

PIK3CD SYK

5.10e-03161992C0334634
Diseaserevision of total joint arthroplasty, aseptic loosening

ELAPOR2 PHLPP1

5.10e-03161992EFO_0010725, EFO_0020974
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

EFCAB13 UGT1A8

5.76e-03171992EFO_0004611, EFO_0007800
DiseaseAcute myeloid leukemia

KIT TERT

5.76e-03171992cv:C0023467
DiseaseLEUKEMIA, ACUTE MYELOID

KIT TERT

5.76e-03171992601626
DiseaseDiuretic use measurement

ARHGAP42 NRIP1 ZNF831 GMDS SLC7A1

5.89e-031691995EFO_0009928
DiseasePremature atrial contractions

ZNF440 ZNF433 ZNF69

6.13e-03551993HP_0006699
Diseasetype 2 diabetes mellitus (is_implicated_in)

PIK3R1 AHSG AKR1B1 GPD2 IGF2R

6.19e-031711995DOID:9352 (is_implicated_in)
DiseaseMajor Depressive Disorder

NPAS3 BDKRB2 ADRA1A NTRK2 TERT MCTP2

6.28e-032431996C1269683
DiseaseAdrenocortical carcinoma

RRM1 TERT

6.45e-03181992C0206686
Diseasepancreatic carcinoma

NOC2L KIT TERT CCDC68 TNS4

6.65e-031741995EFO_0002618

Protein segments in the cluster

PeptideGeneStartEntry
ISKYLKVSSHCNEGT

USP26

541

Q9BXU7
KYCATESLSSLVKQH

ABCA5

716

Q8WWZ7
CGTIYSQTLSIKKLS

BUB1B

656

O60566
KSSCTVAEIYLGNLA

BDKRB2

86

P30411
NTDKLKNISSNYCLG

nan

216

Q9N2K0
SERSCKGALYKTLVS

BBX

611

Q8WY36
LSCYCIIISKLSHSK

CXCR4

216

P61073
CKSKDIVLVAYSALG

AKR1C3

206

P42330
YIVKKCIGRALSSSS

COG4

456

Q9H9E3
LALKAESNLSCGSYL

ADGRG6

346

Q86SQ4
LCRKQSSKHALGYTL

ADRA1A

346

P35348
YTCIAKNTKTLLSGS

CEACAM16

291

Q2WEN9
GIYLTKSNAICHLKS

ARMC2

176

Q8NEN0
TLCLKTQGHSERYKA

ARHGEF16

436

Q5VV41
TAALILKNIGKYSEC

ARID2

1771

Q68CP9
NKTDGCHAYLSKNSL

CAP1

411

Q01518
TLAKTIACYSGQLAA

ANKRD36

1561

A6QL64
AKTIACYSGQLAALT

ANKRD36B

1001

Q8N2N9
LLQLKSSATYGKSCQ

CCDC68

216

Q9H2F9
ELCLLTSGKLSYSLS

CC2D2B

611

Q6DHV5
YADSNCLKTSGIKSQ

ELF5

146

Q9UKW6
QVKYLFSDKTGTLTC

ATP8A2

421

Q9NTI2
GACQKTLSDLKLDYL

AKR1B1

91

P15121
KGTLANSASKDYTLH

NWD1

921

Q149M9
AKTNTVSYKAGLICR

DENND4A

201

Q7Z401
LKSAQCGSSIIYHCK

KLRC1

216

P26715
CKALLDGLNKTTACY

RGS9BP

6

Q6ZS82
KLKGISICYSALKSA

RANBP17

826

Q9H2T7
STQGKYKALSTCASH

OR7A2P

231

Q8NGA2
ALSCIAESLKFYHKG

INTS7

586

Q9NVH2
YSLNGVLQSESKCDK

INO80

96

Q9ULG1
CSKTGYSANIIFHTK

OSBPL9

581

Q96SU4
YKCEVSSLAGALGKL

NOL11

331

Q9H8H0
DLVAGSNCLKSSYVL

GPD2

181

P43304
NSGLLKTLSVYEKHS

LINS1

346

Q8NG48
KVQYAELKLCSSHSP

MCTP2

856

Q6DN12
KALKSSGLCESLTYG

M1AP

311

Q8TC57
SVCGSKLSASALKYL

MCMDC2

576

Q4G0Z9
YSHIQSKCGSKDNIK

MAP4

1001

P27816
LSSVKCFHKLASAYG

LGALS3BP

221

Q08380
YSTVLTKSSLNKGCS

NEDD1

301

Q8NHV4
AGSLSLVLSTCKNIY

NLRC4

701

Q9NPP4
KLHYGDLTDSTCLVK

GMDS

81

O60547
ALYKNLLHSKESSCS

KIT

701

P10721
LCSSYNRGLISKAKI

NPSR1

256

Q6W5P4
GYTNCGKTTLIKALT

GTPBP6

301

O43824
QDYISSCGKKTLHEV

MTURN

71

Q8N3F0
YGILTLCEAFSSQKK

NLRP8

996

Q86W28
SCKLRTLKLSYVSTA

NLRP11

661

P59045
GSLLKKYTALLCTHI

HERC2

1086

O95714
YHSQESDGLVCLLKK

SYK

91

P43405
SLHAKYNTKTCATVV

PHKA1

111

P46020
SSLEGHIYLKIKCQV

ANLN

966

Q9NQW6
LASKLSSGCDYALFK

EIF4E1B

106

A6NMX2
VVKCSIAKSQALYSA

KIAA1109

2866

Q2LD37
KTKSCASLSARYLIQ

BEND2

681

Q8NDZ0
NKLSYLACKLNSLVG

FSIP2

3671

Q5CZC0
TLKSCDLGTILSYQA

CCNYL2

141

Q5T2Q4
LGYAVAVLHKTCSLS

ITGAE

461

P38570
AVLHKTCSLSYIAGA

ITGAE

466

P38570
DSVVLVGYKCLKSTA

FAM135A

516

Q9P2D6
VGYKCLKSTASNDLI

FAM135A

521

Q9P2D6
GVLSKCLAYSKAASD

GPR26

276

Q8NDV2
GKNIDSKLHVTLYNC

PLXNB2

746

O15031
LGCLATSNTEYLSKL

PDZD8

741

Q8NEN9
SYSKTAKQCLEEISG

NAV3

661

Q8IVL0
CSASELKALGYKDVS

CSTF3

536

Q12996
TFSISKIHSLYGKCL

NRDE2

431

Q9H7Z3
KIHSLYGKCLSTLSA

NRDE2

436

Q9H7Z3
YGKCLSTLSAVKDGS

NRDE2

441

Q9H7Z3
KTSADVKALTYCGLQ

KCNH4

641

Q9UQ05
RCYGVASSHLKTLLK

NRIP1

176

P48552
KDKVYGVADSCTSLL

KCNU1

941

A8MYU2
KVLKILLYLCSHGSS

TEPSIN

71

Q96N21
KLQQSSHGYSCSEKL

GPR180

81

Q86V85
SHGYSCSEKLSKAQL

GPR180

86

Q86V85
LNEVKIYSLSCGKSL

NOL10

6

Q9BSC4
KKGLECSTLYRTQSS

PIK3R1

141

P27986
ENLLSDKKTITYAGC

OR5M3

81

Q8NGP4
LGLLYSSTSCGVQKA

PRSS54

21

Q6PEW0
GILSKCLTYSKAVAD

GPR78

276

Q96P69
KAYLGSAIQLVSCLS

NOC2L

251

Q9Y3T9
CYLECSALTQKGLKA

RHOJ

171

Q9H4E5
CTVSLIYAVHLKKSG

ELAPOR2

186

A8MWY0
NSKLCDLLLSKHGIY

ALAS2

486

P22557
SKRLLSTYICKVLGN

EXOC7

541

Q9UPT5
TSLHSLSNCKKLKYI

LRRIQ1

831

Q96JM4
CSHKNKSLQITYSLF

MILR1

56

Q7Z6M3
LYSCVASNVAGTAKK

HMCN1

2266

Q96RW7
CLSGSILAKSKFYGN

OSBPL8

531

Q9BZF1
SSIKSSICLLRGKIY

CDC16

126

Q13042
CSKTSKKGDLLNAHY

FKBP7

46

Q9Y680
DLYSNCKSLKLTLTC

CRISP3

211

P54108
KGELLCSYSNNKSEL

CAPN7

356

Q9Y6W3
KCNTTSTLIIHTYGK

CRTAM

176

O95727
LSIVSSYNTCNKKKG

CTTNBP2

1436

Q8WZ74
LLAEKQYGFCKATLS

AHSG

221

P02765
FCHLYKVTAVLKSQG

DPP9

451

Q86TI2
AKTSKYLLDLCSAQH

FRMPD2

621

Q68DX3
ALLSSGAVLYKACSV

SQLE

546

Q14534
ISKYLLTCKTAHQLT

GON4L

851

Q3T8J9
VLAGIACYAKTSSLT

DNAAF9

381

Q5TEA3
ILLKHKYSFLVGCAS

ANKH

151

Q9HCJ1
EISKVSKHQSYVGLC

ANK3

3021

Q12955
ATDLSSGTINHKKYI

EFCAB13

26

Q8IY85
LCKLPNQYSVHKTSS

EFCAB13

121

Q8IY85
LSKECYSLTGKQSSA

MAB21L2

211

Q9Y586
NYISKAGICHKVSTF

MBLAC2

246

Q68D91
LVGLYCDKLSKTNFS

FBXL5

21

Q9UKA1
TKQYACLHDLTNKGI

FBXL5

441

Q9UKA1
LYDVKTGTCLKSFIQ

EIF2A

111

Q9BY44
ADKGTCKYVSLATLK

H1-9P

126

P60008
YSCDLTTLVKAHTTK

CHN1

266

P15882
TYKLLKSVCGHLENT

GRAMD2B

206

Q96HH9
LSTGKILDQKAYSCA

COL15A1

1356

P39059
LSNKLTYEGKLECGS

DNA2

836

P51530
TVYRLSKGCSLTKAQ

RYR2

2551

Q92736
LAKGSECYQKSLSLN

CDC27

131

P30260
NCIISGSYILTKAAL

FPGT

446

O14772
KVSVNCAKTGYSASI

OSBPL11

586

Q9BXB4
LGVVYTSHLQLKEKC

RGPD1

481

P0DJD0
FLSEKKTISYAGCLT

OR1L8

86

Q8NGR8
GASSRTSLCFKLYAK

MRC1

651

P22897
GLLSYTDKLCSQKDF

NUTM2A

561

Q8IVF1
ISELVNGALTCKYHK

NAV1

1636

Q8NEY1
KSGLSYKSVISFVCR

IGF2R

1601

P11717
LSDVILQCYEGKSSK

RTTN

1841

Q86VV8
LGLRDATSTKYKSVC

SLC9C1

426

Q4G0N8
LCTGIKINSSAYRKA

AIFM2

241

Q9BRQ8
KTITSGLKNYLRCLA

ARHGAP42

451

A6NI28
CYLALSKFTSHLKNL

SAMD9L

1246

Q8IVG5
AIQLYESLAKEGSCK

SEL1L2

166

Q5TEA6
NYTCSIHLGNLVFKK

JAML

231

Q86YT9
SSSAKDEVKLLYLCA

SMG1

241

Q96Q15
EKTKLLYTAGQSTHA

SMG1

1486

Q96Q15
LETCSIALVGKYTKF

CTPS1

296

P17812
KLSSHLKTLSQGSYL

TANC2

641

Q9HCD6
SHLDLLNKGQCVTKY

NPAS3

381

Q8IXF0
LSGLNKETYQSCLKS

ORC6

71

Q9Y5N6
VKCSKSGDLYVLAAD

IARS2

321

Q9NSE4
ILSSCEIKTGYNKTV

STXBP4

161

Q6ZWJ1
SLCLGSQLHGSTKYI

SNRK

651

Q9NRH2
YKHGCKLAIISPTSQ

SRBD1

546

Q8N5C6
GKELLYKFICTTSAI

ACLY

11

P53396
CKSKDIVLVAYSALG

AKR1C1

206

Q04828
CKSKDIVLVAYSALG

AKR1C2

206

P52895
FKESALTLACYKGHL

ANKHD1

371

Q8IWZ3
KLSSTTKGICELENY

CINP

111

Q9BW66
AALLIQGSACVYSKK

NCAPH2

56

Q6IBW4
IKSIGYSDLFCLSKD

CNGA1

561

P29973
GAILNESKYICTKIH

NTRK2

321

Q16620
LQIYCGKAPALSSKA

PIK3CG

431

P48736
NLEVLTSKCLHGKNY

SPG11

1976

Q96JI7
CKGCLVSLSYHLDTK

TRIM74

36

Q86UV6
NVCLAKVKGYRSLST

TLR8

861

Q9NR97
LYECKQCGKALSSLT

ZNF440

311

Q8IYI8
ADHTTLLLNCYTKLK

VPS11

451

Q9H270
IHTTVNSYKLEECGK

ZNF724

191

A8MTY0
HGQYSLLSKITFDKC

ZNF639

356

Q9UID6
QCGKTFSYKSSLVIH

ZNF702P

66

Q9H963
KVSCNICGKLLSAAY

VEZF1

286

Q14119
CTTFGKLCLLSTKYL

ZNF268

181

Q14587
CEKAFSSKSYLLVHQ

ZNF268

281

Q14587
CGKSFSTGSYLIVHK

ZNF177

401

Q13360
STSCLYGKKLSNGSI

PHLPP2

1231

Q6ZVD8
LLYRGTLKCNHSSKT

RLF

1666

Q13129
SGVYTCKLSTAKDEL

SPEG

1036

Q15772
YSSLCSLSDQLAGKI

STEAP3

96

Q658P3
IYDTLKQCALISKSA

RRM1

231

P23921
QKKSAGCHTLYLSSV

TNS4

576

Q8IZW8
VRSLYVSCKSSGKFI

TASL

51

Q9HAI6
KYAVAVGSLCALSAS

SLC7A1

336

P30825
LSTKQTEDYCLASNK

SPINT1

241

O43278
KAYSCALKSGKLVTA

WDHD1

56

O75717
HKSSVTSCLYNLGKL

TMTC2

601

Q8N394
HKGGYDELKQCLTTT

ZNF723

126

P0DPD5
GALCYAELGTTIKKS

SLC7A7

86

Q9UM01
YILKGHKNTVCSLSS

PLAA

106

Q9Y263
SLTTTQSKVFQCGKY

ZNF728

136

P0DKX0
KCKAGFNSYAELLTH

ZNF292

756

O60281
ISCFTQKLVEKLYSG

WDFY4

1961

Q6ZS81
KLHTCGKQFYISANL

ZNF211

136

Q13398
CSKDIQYLKDSLALG

PIK3CD

991

O00329
GKNLTINCTSSKTLY

TRAV34

36

A0A0B4J273
CEYVSSLSKKGSLLV

ATP6AP1

371

Q15904
CFIKISAAYGSTKDI

PITPNM3

831

Q9BZ71
KTKYAKSQSLGIICH

ZMYM2

571

Q9UBW7
CEKLFSYKSSLIIHQ

ZNF717

316

Q9BY31
KQCGKSFSYSATLRI

ZNF69

251

Q9UC07
SECGKAFSSKSYLVI

ZNF26

401

P17031
VCGKAYISRSSLKNH

ZFP62

481

Q8NB50
CGKAYISLSSLINHK

ZFP62

566

Q8NB50
YSGLNQCLKTTLSKI

ZNF117

66

Q03924
CKGCLVSLSYHLDTK

TRIM73

36

Q86UV7
LAAAKKLCTLAQSYG

PHLPP1

1396

O60346
HESCSGLYKLSLSGL

USP34

1671

Q70CQ2
KSTLTGNKVFNCISY

WDR12

291

Q9GZL7
TCGIAFKTQSNLYKH

ZNF831

176

Q5JPB2
KSSGCSTYINRLIKV

SHE

136

Q5VZ18
LLELASTTKCSSVKY

UBR4

1071

Q5T4S7
SLYAIVLCKHKGITS

TMEM254

76

Q8TBM7
SACTYGKSIDLVKFL

TNNI3K

311

Q59H18
CEKSYFLKGSLVTHQ

ZNF425

251

Q6IV72
KHCGKVLSYLTSFQN

ZNF433

341

Q8N7K0
NKHYSCPTSEGIQKL

TBC1D2B

721

Q9UPU7
GKSLYCQAITTHSKS

HIVEP1

1996

P15822
ISDTASLCYSILKAK

TERT

1036

O14746
ANGVSLLKDLYKCSE

UNC45A

476

Q9H3U1
LCCTTSYKVKQAGLT

ZMYM3

526

Q14202
CGKAYTQRSSLTKHL

ZNF836

671

Q6ZNA1
SCRLKTHISNKYGKN

ZNF816

196

Q0VGE8
ASESLCGLKLEVNKY

TIMP3

86

P35625
LGKSLNCTVKTYSTS

UGT1A8

66

Q9HAW9
LHTSKACNIISKYTA

VWA5B1

886

Q5TIE3
CVGKSFHTYDVQKLS

WDR36

101

Q8NI36
CVLISSKAVYFLKSG

VPS13D

4276

Q5THJ4
RVKYNKGLTCSSITI

KLK10

181

O43240
DGLSQCLASRKYSKN

LONRF3

506

Q496Y0