Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	FOXJ2 HOXA9 ONECUT2 OTX1 SHOX MAFB POU4F1 POU4F2 DLX2 ONECUT1 CREB5 FOXF2 FOXC2	1.74e-09	560	53	13	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	FOXJ2 HOXA9 ONECUT2 OTX1 SHOX MAFB POU4F1 POU4F2 DLX2 ONECUT1 CREB5 FOXF2 FOXC2	1.98e-09	566	53	13	GO:0001216
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	FOXJ2 HOXA9 ONECUT2 OTX1 GATA6 HEY2 SHOX SHOX2 GSX2 MAFB POU4F1 POU4F2 DLX2 ONECUT1 CREB5 FOXF2 FOXC2	7.04e-08	1412	53	17	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	FOXJ2 HOXA9 ONECUT2 OTX1 GATA6 HEY2 MAFB POU4F1 POU4F2 DLX2 ONECUT1 CREB5 FOXF2 FOXC2	2.99e-06	1244	53	14	GO:0000978
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	FOXJ2 HOXA9 ONECUT2 GTF2A1 OTX1 GATA6 HEY2 MAFB POU4F1 POU4F2 DLX2 ONECUT1 CREB5 FOXF2 FOXC2	3.71e-06	1459	53	15	GO:0000977
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	FOXJ2 HOXA9 ONECUT2 OTX1 GATA6 HEY2 MAFB POU4F1 POU4F2 DLX2 ONECUT1 CREB5 FOXF2 FOXC2	3.84e-06	1271	53	14	GO:0000987
GeneOntologyMolecularFunction	chromatin binding	GATA6 AUTS2 PRDM13 CHD8 POU4F1 POU4F2 DLX2 ONECUT1 NONO FOXC2	2.09e-05	739	53	10	GO:0003682
GeneOntologyMolecularFunction	transcription factor binding	GTF2A1 GATA6 HEY2 PRDM13 POU4F1 PBXIP1 NLK FOXF2	7.77e-04	753	53	8	GO:0008134
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	GTF2A1 GATA6 HEY2 PRDM13 POU4F1 PBXIP1 NLK	8.31e-04	582	53	7	GO:0140297
GeneOntologyMolecularFunction	RNA polymerase II general transcription initiation factor binding	GTF2A1 FOXF2	2.33e-03	27	53	2	GO:0001091
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	FOXJ2 HOXA9 ONECUT2 GTF2A1 TSC22D1 SENP1 OTX1 GATA6 HEY2 AUTS2 SHOX MAFB CHD8 POU4F1 POU4F2 DLX2 ONECUT1 CREB5 FOXF2 FOXC2	5.12e-11	1390	52	20	GO:0045944
GeneOntologyBiologicalProcess	cell fate commitment	ONECUT2 GATA6 HEY2 GSX2 POU4F1 DLX2 ONECUT1 FOXC2	1.92e-06	338	52	8	GO:0045165
GeneOntologyBiologicalProcess	pattern specification process	HOXA9 OTX1 NKD1 HEY2 GSX2 MAFB DLX2 RNF111 FOXC2	5.91e-06	526	52	9	GO:0007389
GeneOntologyBiologicalProcess	animal organ morphogenesis	HOXA9 ONECUT2 OTX1 NKD1 GATA6 HEY2 SHOX2 GSX2 MAFB POU4F1 DLX2 FOXF2 FOXC2	1.13e-05	1269	52	13	GO:0009887
GeneOntologyBiologicalProcess	regionalization	HOXA9 OTX1 NKD1 HEY2 GSX2 MAFB DLX2 FOXC2	2.41e-05	478	52	8	GO:0003002
GeneOntologyBiologicalProcess	embryonic organ morphogenesis	HOXA9 OTX1 SHOX2 MAFB DLX2 FOXF2 FOXC2	2.70e-05	351	52	7	GO:0048562
GeneOntologyBiologicalProcess	GABAergic neuron differentiation	PRDM13 GSX2 DLX2	2.95e-05	24	52	3	GO:0097154
GeneOntologyBiologicalProcess	negative regulation of DNA-templated transcription	GATA6 HEY2 PRDM13 SHOX2 MAFB CHD8 POU4F1 POU4F2 DLX2 NONO PBXIP1 FOXF2 FOXC2	3.19e-05	1399	52	13	GO:0045892
GeneOntologyBiologicalProcess	negative regulation of RNA biosynthetic process	GATA6 HEY2 PRDM13 SHOX2 MAFB CHD8 POU4F1 POU4F2 DLX2 NONO PBXIP1 FOXF2 FOXC2	3.54e-05	1413	52	13	GO:1902679
GeneOntologyBiologicalProcess	cardiac chamber morphogenesis	GATA6 HEY2 SHOX2 POU4F1 FOXC2	5.26e-05	161	52	5	GO:0003206
GeneOntologyBiologicalProcess	embryonic organ development	HOXA9 OTX1 HEY2 SHOX2 MAFB DLX2 FOXF2 FOXC2	7.47e-05	561	52	8	GO:0048568
GeneOntologyBiologicalProcess	muscle tissue morphogenesis	HEY2 SHOX2 POU4F1 FOXC2	8.88e-05	93	52	4	GO:0060415
GeneOntologyBiologicalProcess	muscle organ morphogenesis	HEY2 SHOX2 POU4F1 FOXC2	1.27e-04	102	52	4	GO:0048644
GeneOntologyBiologicalProcess	cardiac conduction system development	GATA6 HEY2 SHOX2	1.40e-04	40	52	3	GO:0003161
GeneOntologyBiologicalProcess	embryonic skeletal system morphogenesis	HOXA9 SHOX2 DLX2 FOXC2	1.64e-04	109	52	4	GO:0048704
GeneOntologyBiologicalProcess	Notch signaling pathway	HEY2 GSX2 DLX2 ONECUT1 FOXC2	1.84e-04	210	52	5	GO:0007219
GeneOntologyBiologicalProcess	cardiac chamber development	GATA6 HEY2 SHOX2 POU4F1 FOXC2	1.92e-04	212	52	5	GO:0003205
GeneOntologyBiologicalProcess	regulation of transcription regulatory region DNA binding	HEY2 POU4F1 POU4F2	2.13e-04	46	52	3	GO:2000677
GeneOntologyBiologicalProcess	connective tissue development	SHOX2 POU4F2 DLX2 PBXIP1 CREB5 FOXC2	2.16e-04	343	52	6	GO:0061448
GeneOntologyBiologicalProcess	regulation of amacrine cell differentiation	POU4F2 DLX2	2.22e-04	9	52	2	GO:1902869
GeneOntologyBiologicalProcess	negative regulation of transcription by RNA polymerase II	GATA6 HEY2 PRDM13 SHOX2 MAFB CHD8 POU4F1 POU4F2 DLX2 FOXC2	2.57e-04	1053	52	10	GO:0000122
GeneOntologyBiologicalProcess	regulation of cell development	HOXA9 TSC22D1 SENP1 HEY2 SHOX2 GSX2 MAFB POU4F1 POU4F2 DLX2	3.51e-04	1095	52	10	GO:0060284
GeneOntologyBiologicalProcess	embryonic morphogenesis	HOXA9 OTX1 GATA6 SHOX2 MAFB DLX2 FOXF2 FOXC2	3.84e-04	713	52	8	GO:0048598
GeneOntologyBiologicalProcess	anterior/posterior pattern specification	HOXA9 OTX1 NKD1 HEY2 FOXC2	3.88e-04	247	52	5	GO:0009952
GeneOntologyBiologicalProcess	ventricular cardiac muscle tissue morphogenesis	HEY2 POU4F1 FOXC2	4.45e-04	59	52	3	GO:0055010
GeneOntologyBiologicalProcess	sensory organ development	OTX1 NKD1 HEY2 MAFB POU4F2 DLX2 FOXF2 FOXC2	4.49e-04	730	52	8	GO:0007423
GeneOntologyBiologicalProcess	negative regulation of apoptotic process	TSC22D1 PLK2 CPEB4 GATA6 HEY2 CHD8 POU4F1 CBL NONO FOXC2	4.60e-04	1133	52	10	GO:0043066
GeneOntologyBiologicalProcess	sinoatrial node development	GATA6 SHOX2	4.78e-04	13	52	2	GO:0003163
GeneOntologyBiologicalProcess	endocrine pancreas development	ONECUT2 GATA6 ONECUT1	4.91e-04	61	52	3	GO:0031018
GeneOntologyBiologicalProcess	embryonic skeletal system development	HOXA9 SHOX2 DLX2 FOXC2	5.27e-04	148	52	4	GO:0048706
GeneOntologyBiologicalProcess	Rap protein signal transduction	PLK2 CBL	5.56e-04	14	52	2	GO:0032486
GeneOntologyBiologicalProcess	pancreatic A cell differentiation	GATA6 ONECUT1	5.56e-04	14	52	2	GO:0003310
GeneOntologyBiologicalProcess	regulation of cellular response to growth factor stimulus	ONECUT2 TSC22D1 GATA6 HRG ONECUT1 RNF111	5.74e-04	412	52	6	GO:0090287
GeneOntologyBiologicalProcess	digestive tract development	GATA6 SHOX2 CHD8 FOXF2	5.83e-04	152	52	4	GO:0048565
GeneOntologyBiologicalProcess	negative regulation of programmed cell death	TSC22D1 PLK2 CPEB4 GATA6 HEY2 CHD8 POU4F1 CBL NONO FOXC2	5.96e-04	1171	52	10	GO:0043069
GeneOntologyBiologicalProcess	branching morphogenesis of a nerve	SHOX2 DLX2	6.41e-04	15	52	2	GO:0048755
GeneOntologyBiologicalProcess	blood vessel endothelial cell differentiation	FOXJ2 HEY2	6.41e-04	15	52	2	GO:0060837
GeneOntologyBiologicalProcess	transforming growth factor beta receptor signaling pathway	ONECUT2 TSC22D1 ONECUT1 NLK RNF111	6.43e-04	276	52	5	GO:0007179
GeneOntologyBiologicalProcess	peripheral nervous system neuron development	ONECUT2 POU4F1	7.31e-04	16	52	2	GO:0048935
GeneOntologyBiologicalProcess	peripheral nervous system neuron differentiation	ONECUT2 POU4F1	7.31e-04	16	52	2	GO:0048934
GeneOntologyBiologicalProcess	embryo development	HOXA9 OTX1 NKD1 GATA6 HEY2 SHOX2 MAFB CHD8 DLX2 FOXF2 FOXC2	7.66e-04	1437	52	11	GO:0009790
GeneOntologyBiologicalProcess	regulation of myeloid cell differentiation	HOXA9 SENP1 MAFB POU4F1 POU4F2	7.79e-04	288	52	5	GO:0045637
GeneOntologyBiologicalProcess	negative regulation of developmental process	FOXJ2 HOXA9 TSC22D1 PLK2 HEY2 HRG MAFB POU4F2 DLX2 FOXC2	8.19e-04	1220	52	10	GO:0051093
GeneOntologyBiologicalProcess	digestive system development	GATA6 SHOX2 CHD8 FOXF2	8.29e-04	167	52	4	GO:0055123
GeneOntologyBiologicalProcess	transforming growth factor beta receptor superfamily signaling pathway	ONECUT2 TSC22D1 GATA6 ONECUT1 NLK RNF111	8.57e-04	445	52	6	GO:0141091
GeneOntologyBiologicalProcess	cardiac vascular smooth muscle cell differentiation	GATA6 HEY2	9.29e-04	18	52	2	GO:0060947
GeneOntologyBiologicalProcess	amacrine cell differentiation	POU4F2 DLX2	9.29e-04	18	52	2	GO:0035881
GeneOntologyBiologicalProcess	ventricular cardiac muscle tissue development	HEY2 POU4F1 FOXC2	9.33e-04	76	52	3	GO:0003229
GeneOntologyBiologicalProcess	cardiac muscle tissue morphogenesis	HEY2 POU4F1 FOXC2	9.69e-04	77	52	3	GO:0055008
GeneOntologyBiologicalProcess	forebrain morphogenesis	OTX1 GSX2	1.04e-03	19	52	2	GO:0048853
GeneOntologyBiologicalProcess	positive regulation of transcription regulatory region DNA binding	POU4F1 POU4F2	1.15e-03	20	52	2	GO:2000679
GeneOntologyBiologicalProcess	cardiac muscle cell proliferation	GATA6 HEY2 FOXC2	1.16e-03	82	52	3	GO:0060038
GeneOntologyBiologicalProcess	cellular response to growth factor stimulus	ONECUT2 TSC22D1 GATA6 HRG CBL ONECUT1 NLK RNF111	1.21e-03	850	52	8	GO:0071363
GeneOntologyBiologicalProcess	regulation of cardiac muscle cell apoptotic process	GATA6 HEY2 POU4F2	1.25e-03	84	52	3	GO:0010665
GeneOntologyBiologicalProcess	heart morphogenesis	GATA6 HEY2 SHOX2 POU4F1 FOXC2	1.26e-03	321	52	5	GO:0003007
GeneOntologyBiologicalProcess	cell surface receptor protein serine/threonine kinase signaling pathway	ONECUT2 TSC22D1 GATA6 ONECUT1 NLK RNF111	1.29e-03	482	52	6	GO:0007178
GeneOntologyBiologicalProcess	brain development	SELENOP OTX1 PRDM13 GSX2 MAFB CHD8 POU4F1 DLX2	1.30e-03	859	52	8	GO:0007420
GeneOntologyBiologicalProcess	cardiac muscle tissue development	GATA6 HEY2 SHOX2 POU4F1 FOXC2	1.37e-03	327	52	5	GO:0048738
GeneOntologyBiologicalProcess	regulation of transforming growth factor beta receptor signaling pathway	ONECUT2 TSC22D1 ONECUT1 RNF111	1.39e-03	192	52	4	GO:0017015
GeneOntologyBiologicalProcess	sensory system development	NKD1 POU4F1 POU4F2 DLX2 FOXF2 FOXC2	1.42e-03	491	52	6	GO:0048880
GeneOntologyBiologicalProcess	regulation of striated muscle cell apoptotic process	GATA6 HEY2 POU4F2	1.43e-03	88	52	3	GO:0010662
GeneOntologyBiologicalProcess	cardiac ventricle morphogenesis	HEY2 POU4F1 FOXC2	1.43e-03	88	52	3	GO:0003208
GeneOntologyBiologicalProcess	regulation of cellular response to transforming growth factor beta stimulus	ONECUT2 TSC22D1 ONECUT1 RNF111	1.47e-03	195	52	4	GO:1903844
GeneOntologyBiologicalProcess	cellular response to oxygen levels	CPEB4 GATA6 POU4F2 CBL	1.47e-03	195	52	4	GO:0071453
GeneOntologyBiologicalProcess	cardiac muscle cell apoptotic process	GATA6 HEY2 POU4F2	1.52e-03	90	52	3	GO:0010659
GeneOntologyBiologicalProcess	diencephalon development	OTX1 PRDM13 POU4F1	1.52e-03	90	52	3	GO:0021536
GeneOntologyBiologicalProcess	response to growth factor	ONECUT2 TSC22D1 GATA6 HRG CBL ONECUT1 NLK RNF111	1.54e-03	883	52	8	GO:0070848
GeneOntologyBiologicalProcess	cellular response to transforming growth factor beta stimulus	ONECUT2 TSC22D1 ONECUT1 NLK RNF111	1.55e-03	336	52	5	GO:0071560
GeneOntologyBiologicalProcess	regulation of locomotion	ONECUT2 PLK2 CATSPER1 NKD1 HRG GSX2 POU4F2 ONECUT1 LRCH1 FOXC2	1.55e-03	1327	52	10	GO:0040012
GeneOntologyBiologicalProcess	neuron fate commitment	GSX2 POU4F1 DLX2	1.57e-03	91	52	3	GO:0048663
GeneOntologyBiologicalProcess	response to transforming growth factor beta	ONECUT2 TSC22D1 ONECUT1 NLK RNF111	1.69e-03	343	52	5	GO:0071559
GeneOntologyBiologicalProcess	outflow tract morphogenesis	GATA6 HEY2 FOXC2	1.72e-03	94	52	3	GO:0003151
GeneOntologyBiologicalProcess	striated muscle cell apoptotic process	GATA6 HEY2 POU4F2	1.72e-03	94	52	3	GO:0010658
GeneOntologyBiologicalProcess	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway	ONECUT2 TSC22D1 GATA6 ONECUT1 RNF111	1.78e-03	347	52	5	GO:0090092
GeneOntologyBiologicalProcess	atrial cardiac muscle tissue development	GATA6 SHOX2	1.80e-03	25	52	2	GO:0003228
GeneOntologyBiologicalProcess	regulation of neurogenesis	HEY2 SHOX2 GSX2 POU4F1 POU4F2 DLX2	1.81e-03	515	52	6	GO:0050767
GeneOntologyBiologicalProcess	chordate embryonic development	HOXA9 NKD1 GATA6 HEY2 SHOX2 CHD8 DLX2 FOXC2	1.82e-03	906	52	8	GO:0043009
GeneOntologyBiologicalProcess	striated muscle tissue development	GATA6 HEY2 SHOX2 POU4F1 FOXC2	1.83e-03	349	52	5	GO:0014706
GeneOntologyBiologicalProcess	hindbrain development	OTX1 GSX2 MAFB POU4F1	1.86e-03	208	52	4	GO:0030902
GeneOntologyBiologicalProcess	head development	SELENOP OTX1 PRDM13 GSX2 MAFB CHD8 POU4F1 DLX2	1.99e-03	919	52	8	GO:0060322
GeneOntologyBiologicalProcess	definitive hemopoiesis	HOXA9 SENP1	2.10e-03	27	52	2	GO:0060216
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	HOXA9 NKD1 GATA6 HEY2 SHOX2 CHD8 DLX2 FOXC2	2.13e-03	929	52	8	GO:0009792
GeneOntologyBiologicalProcess	pancreas development	ONECUT2 GATA6 ONECUT1	2.18e-03	102	52	3	GO:0031016
GeneOntologyBiologicalProcess	subpallium development	GSX2 DLX2	2.26e-03	28	52	2	GO:0021544
GeneOntologyBiologicalProcess	regulation of hemopoiesis	HOXA9 TSC22D1 SENP1 MAFB POU4F1 POU4F2	2.30e-03	540	52	6	GO:1903706
GeneOntologyBiologicalProcess	regulation of Wnt signaling pathway	USP34 NKD1 CHD8 PBXIP1 NLK	2.30e-03	368	52	5	GO:0030111
GeneOntologyBiologicalProcess	enzyme-linked receptor protein signaling pathway	ONECUT2 TSC22D1 GATA6 HRG CBL ONECUT1 NLK RNF111 FOXC2	2.61e-03	1186	52	9	GO:0007167
GeneOntologyBiologicalProcess	striated muscle cell proliferation	GATA6 HEY2 FOXC2	2.70e-03	110	52	3	GO:0014855
GeneOntologyCellularComponent	chromatin	FOXJ2 HOXA9 ONECUT2 PLK2 OTX1 GATA6 HEY2 SHOX SHOX2 GSX2 MAFB CHD8 POU4F1 POU4F2 DLX2 ONECUT1 PBXIP1 CREB5 FOXF2 FOXC2	1.86e-10	1480	53	20	GO:0000785
GeneOntologyCellularComponent	transcription regulator complex	HOXA9 GTF2A1 GATA6 HEY2 MAFB POU4F1 POU4F2 NONO PBXIP1 FOXF2	2.13e-06	596	53	10	GO:0005667
MousePheno	abnormal pterygoid bone morphology	DLX2 MN1 FOXF2 FOXC2	4.98e-08	12	46	4	MP:0004453
MousePheno	neonatal lethality	GTF2A1 OTX1 CPEB4 HEY2 AUTS2 GSX2 MAFB POU4F1 DLX2 CBL MN1 CREB5 NLK FOXF2	1.53e-07	799	46	14	MP:0002058
MousePheno	abnormal pterygoid process morphology	DLX2 MN1 FOXF2 FOXC2	5.89e-07	21	46	4	MP:0004452
MousePheno	small pterygoid bone	DLX2 MN1 FOXC2	1.16e-06	7	46	3	MP:0004456
MousePheno	perinatal lethality	GTF2A1 OTX1 CPEB4 HEY2 AUTS2 GSX2 MAFB POU4F1 DLX2 CBL MN1 CREB5 NLK FOXF2 FOXC2	1.75e-06	1130	46	15	MP:0002081
MousePheno	abnormal suckling behavior	GTF2A1 CPEB4 POU4F1 DLX2 MN1 FOXF2	1.76e-06	113	46	6	MP:0001436
MousePheno	abnormal palatine bone horizontal plate morphology	DLX2 MN1 FOXF2 FOXC2	1.98e-06	28	46	4	MP:0004537
MousePheno	perinatal lethality, complete penetrance	OTX1 HEY2 AUTS2 GSX2 MAFB POU4F1 DLX2 MN1 CREB5 NLK FOXF2 FOXC2	2.18e-06	712	46	12	MP:0011089
MousePheno	neonatal lethality, complete penetrance	OTX1 HEY2 AUTS2 GSX2 MAFB POU4F1 DLX2 CREB5 NLK FOXF2	7.17e-06	534	46	10	MP:0011087
MousePheno	absent soft palate	FOXF2 FOXC2	1.06e-05	2	46	2	MP:0030290
MousePheno	absent palatine bone horizontal plate	DLX2 FOXF2 FOXC2	1.18e-05	14	46	3	MP:0000431
MousePheno	abnormal sphenoid bone morphology	OTX1 DLX2 MN1 FOXF2 FOXC2	1.43e-05	95	46	5	MP:0000104
MousePheno	abnormal palatine bone morphology	DLX2 MN1 FOXF2 FOXC2	1.51e-05	46	46	4	MP:0005249
MousePheno	abnormal palate bone morphology	DLX2 MN1 FOXF2 FOXC2	2.29e-05	51	46	4	MP:0009891
MousePheno	abnormal orbit morphology	OTX1 FOXF2 FOXC2	2.63e-05	18	46	3	MP:0010030
MousePheno	lethality during fetal growth through weaning, complete penetrance	SENP1 OTX1 HEY2 AUTS2 SHOX2 GSX2 MAFB POU4F1 DLX2 MN1 CREB5 NLK FOXF2 FOXC2	3.58e-05	1269	46	14	MP:0011111
MousePheno	meteorism	OTX1 DLX2 FOXF2	3.66e-05	20	46	3	MP:0009247
MousePheno	abnormal alisphenoid bone morphology	DLX2 MN1 FOXC2	4.25e-05	21	46	3	MP:0003235
MousePheno	cleft secondary palate	SHOX2 DLX2 MN1 FOXF2 FOXC2	5.82e-05	127	46	5	MP:0009890
MousePheno	abnormal temporal bone morphology	MAFB DLX2 MN1 FOXC2	6.37e-05	66	46	4	MP:0005272
MousePheno	abnormal hard palate morphology	DLX2 MN1 FOXF2 FOXC2	6.76e-05	67	46	4	MP:0003756
MousePheno	abnormal maxillary shelf morphology	DLX2 MN1 FOXF2	1.15e-04	29	46	3	MP:0004538
MousePheno	abnormal secondary palate morphology	SHOX2 DLX2 MN1 FOXF2 FOXC2	1.68e-04	159	46	5	MP:0013550
MousePheno	abnormal presphenoid bone morphology	MN1 FOXF2 FOXC2	1.70e-04	33	46	3	MP:0004448
MousePheno	abnormal neurocranium morphology	OTX1 MAFB DLX2 MN1 FOXF2 FOXC2	2.36e-04	269	46	6	MP:0000074
MousePheno	abnormal orbitosphenoid bone morphology	OTX1 FOXF2	2.93e-04	8	46	2	MP:0004457
MousePheno	absent gastric milk in neonates	CPEB4 GSX2 POU4F1 FOXF2	3.45e-04	102	46	4	MP:0009546
MousePheno	abnormal ciliary process morphology	OTX1 FOXF2	3.76e-04	9	46	2	MP:0014164
MousePheno	abnormal canal of Schlemm morphology	FOXF2 FOXC2	3.76e-04	9	46	2	MP:0005204
MousePheno	abnormal breathing pattern	CPEB4 HEY2 GSX2 MAFB DLX2 MN1	4.46e-04	303	46	6	MP:0001951
MousePheno	abnormal soft palate morphology	FOXF2 FOXC2	4.69e-04	10	46	2	MP:0003154
MousePheno	abnormal iris stroma morphology	FOXF2 FOXC2	4.69e-04	10	46	2	MP:0005208
MousePheno	abnormal trabecular meshwork morphology	FOXF2 FOXC2	4.69e-04	10	46	2	MP:0005203
MousePheno	respiratory distress	CPEB4 HEY2 MAFB DLX2 MN1	5.31e-04	204	46	5	MP:0001954
MousePheno	biliary cyst	AUTS2 ONECUT1	5.72e-04	11	46	2	MP:0003266
MousePheno	postnatal lethality	SELENOP SENP1 OTX1 CPEB4 FBXO41 HEY2 SHOX2 MAFB CBL ONECUT1 FOXF2	6.17e-04	1084	46	11	MP:0002082
MousePheno	abnormal axial skeleton morphology	HOXA9 VGLL3 OTX1 NKD1 FAM120C SKIDA1 SHOX2 MAFB DLX2 MN1 PBXIP1 FOXF2 FOXC2	6.17e-04	1458	46	13	MP:0002114
MousePheno	abnormal palatal shelf morphology	SHOX2 DLX2 MN1 FOXF2	6.58e-04	121	46	4	MP:0031460
MousePheno	abnormal basicranium morphology	MAFB DLX2 MN1 FOXC2	7.00e-04	123	46	4	MP:0010029
MousePheno	abnormal eating behavior	GTF2A1 CPEB4 GSX2 POU4F1 DLX2 CBL MN1 FOXF2	7.07e-04	604	46	8	MP:0001431
MousePheno	abnormal secondary palate development	SHOX2 DLX2 MN1 FOXF2	7.22e-04	124	46	4	MP:0009655
MousePheno	lethality during fetal growth through weaning, incomplete penetrance	GTF2A1 SELENOP SENP1 OTX1 CPEB4 FBXO41 HEY2 SHOX2 CBL ONECUT1 MN1	8.36e-04	1124	46	11	MP:0011112
MousePheno	aphagia	CPEB4 GSX2 POU4F1 FOXF2	8.37e-04	129	46	4	MP:0001438
MousePheno	abnormal palate development	SHOX2 DLX2 MN1 FOXF2	8.37e-04	129	46	4	MP:0009653
MousePheno	abnormal basisphenoid bone morphology	DLX2 MN1 FOXC2	8.62e-04	57	46	3	MP:0000106
MousePheno	kidney hemorrhage	MAFB FOXC2	9.40e-04	14	46	2	MP:0000533
MousePheno	abnormal bile duct development	ONECUT2 ONECUT1	1.08e-03	15	46	2	MP:0002929
MousePheno	abnormal cranium morphology	OTX1 NKD1 FAM120C SHOX2 MAFB DLX2 MN1 FOXF2 FOXC2	1.15e-03	813	46	9	MP:0000438
MousePheno	abnormal bile duct morphology	ONECUT2 AUTS2 ONECUT1	1.21e-03	64	46	3	MP:0002928
MousePheno	abnormal amacrine cell number	PRDM13 POU4F2	1.23e-03	16	46	2	MP:0008104
MousePheno	craniofacial phenotype	OTX1 NKD1 FAM120C SHOX2 GSX2 MAFB DLX2 CBL NONO MN1 FOXF2 FOXC2	1.25e-03	1372	46	12	MP:0005382
MousePheno	abnormal craniofacial morphology	OTX1 NKD1 FAM120C SHOX2 GSX2 MAFB DLX2 CBL NONO MN1 FOXF2 FOXC2	1.25e-03	1372	46	12	MP:0000428
MousePheno	distended abdomen	OTX1 DLX2 FOXF2	1.26e-03	65	46	3	MP:0001270
MousePheno	abnormal craniofacial bone morphology	OTX1 NKD1 FAM120C SHOX2 MAFB DLX2 MN1 FOXF2 FOXC2	1.29e-03	827	46	9	MP:0002116
MousePheno	abnormal stationary movement	OTX1 MAFB POU4F1 POU4F2	1.36e-03	147	46	4	MP:0001388
MousePheno	small middle ear ossicles	DLX2 FOXC2	1.40e-03	17	46	2	MP:0030123
MousePheno	abnormal consumption behavior	GTF2A1 CPEB4 GSX2 POU4F1 DLX2 CBL MN1 FOXF2	1.75e-03	695	46	8	MP:0002069
MousePheno	abnormal endocrine pancreas development	MAFB ONECUT1	1.75e-03	19	46	2	MP:0011932
MousePheno	abnormal hepatobiliary system development	ONECUT2 GATA6 ONECUT1	1.84e-03	74	46	3	MP:0003943
MousePheno	abnormal respiratory function	CPEB4 HEY2 GSX2 MAFB DLX2 MN1	1.86e-03	399	46	6	MP:0002327
MousePheno	abnormal otic vesicle development	MAFB FOXC2	1.94e-03	20	46	2	MP:0006030
MousePheno	abnormal hindbrain development	OTX1 FBXO41 GSX2 MAFB	2.03e-03	164	46	4	MP:0006108
MousePheno	abnormal nervous system development	OTX1 CPEB4 NUFIP2 FBXO41 AUTS2 GSX2 MAFB CHD8 DLX2 RNF111 FOXC2	2.08e-03	1257	46	11	MP:0003861
MousePheno	abnormal temporal bone squamous part morphology	MN1 FOXC2	2.14e-03	21	46	2	MP:0004423
MousePheno	abnormal iridocorneal angle	FOXF2 FOXC2	2.14e-03	21	46	2	MP:0004221
MousePheno	abnormal superior colliculus morphology	OTX1 POU4F2	2.14e-03	21	46	2	MP:0000904
MousePheno	small interparietal bone	MN1 FOXC2	2.14e-03	21	46	2	MP:0004384
Domain	Homeobox	HOXA9 ONECUT2 OTX1 SHOX SHOX2 GSX2 POU4F1 POU4F2 DLX2 ONECUT1	9.57e-10	234	53	10	PF00046
Domain	HOMEOBOX_1	HOXA9 ONECUT2 OTX1 SHOX SHOX2 GSX2 POU4F1 POU4F2 DLX2 ONECUT1	1.04e-09	236	53	10	PS00027
Domain	HOX	HOXA9 ONECUT2 OTX1 SHOX SHOX2 GSX2 POU4F1 POU4F2 DLX2 ONECUT1	1.08e-09	237	53	10	SM00389
Domain	Homeobox_dom	HOXA9 ONECUT2 OTX1 SHOX SHOX2 GSX2 POU4F1 POU4F2 DLX2 ONECUT1	1.17e-09	239	53	10	IPR001356
Domain	HOMEOBOX_2	HOXA9 ONECUT2 OTX1 SHOX SHOX2 GSX2 POU4F1 POU4F2 DLX2 ONECUT1	1.17e-09	239	53	10	PS50071
Domain	-	HOXA9 ONECUT2 OTX1 SHOX SHOX2 GSX2 POU4F1 POU4F2 DLX2 ONECUT1	5.98e-09	283	53	10	1.10.10.60
Domain	Homeodomain-like	HOXA9 ONECUT2 OTX1 SHOX SHOX2 GSX2 POU4F1 POU4F2 DLX2 ONECUT1	2.72e-08	332	53	10	IPR009057
Domain	Homeobox_CS	HOXA9 OTX1 SHOX SHOX2 GSX2 POU4F1 POU4F2 DLX2	5.03e-08	186	53	8	IPR017970
Domain	-	ONECUT2 POU4F1 POU4F2 ONECUT1	9.66e-07	27	53	4	1.10.260.40
Domain	Lambda_DNA-bd_dom	ONECUT2 POU4F1 POU4F2 ONECUT1	1.30e-06	29	53	4	IPR010982
Domain	HTH_motif	HOXA9 SHOX SHOX2 DLX2	4.36e-05	69	53	4	IPR000047
Domain	CUT	ONECUT2 ONECUT1	1.64e-04	7	53	2	PF02376
Domain	CUT_dom	ONECUT2 ONECUT1	1.64e-04	7	53	2	IPR003350
Domain	CUT	ONECUT2 ONECUT1	1.64e-04	7	53	2	SM01109
Domain	CUT	ONECUT2 ONECUT1	1.64e-04	7	53	2	PS51042
Domain	TF_fork_head_CS_2	FOXJ2 FOXF2 FOXC2	3.00e-04	46	53	3	IPR030456
Domain	TF_fork_head_CS_1	FOXJ2 FOXF2 FOXC2	3.20e-04	47	53	3	IPR018122
Domain	FORK_HEAD_3	FOXJ2 FOXF2 FOXC2	3.62e-04	49	53	3	PS50039
Domain	FH	FOXJ2 FOXF2 FOXC2	3.62e-04	49	53	3	SM00339
Domain	FORK_HEAD_1	FOXJ2 FOXF2 FOXC2	3.62e-04	49	53	3	PS00657
Domain	FORK_HEAD_2	FOXJ2 FOXF2 FOXC2	3.62e-04	49	53	3	PS00658
Domain	Forkhead	FOXJ2 FOXF2 FOXC2	3.62e-04	49	53	3	PF00250
Domain	Fork_head_dom	FOXJ2 FOXF2 FOXC2	3.62e-04	49	53	3	IPR001766
Domain	OAR	SHOX SHOX2	8.10e-04	15	53	2	PF03826
Domain	OAR	SHOX SHOX2	9.24e-04	16	53	2	PS50803
Domain	POU	POU4F1 POU4F2	9.24e-04	16	53	2	SM00352
Domain	POU_2	POU4F1 POU4F2	9.24e-04	16	53	2	PS00465
Domain	Pou	POU4F1 POU4F2	9.24e-04	16	53	2	PF00157
Domain	POU_dom	POU4F1 POU4F2	9.24e-04	16	53	2	IPR000327
Domain	POU_3	POU4F1 POU4F2	9.24e-04	16	53	2	PS51179
Domain	POU_1	POU4F1 POU4F2	9.24e-04	16	53	2	PS00035
Domain	OAR_dom	SHOX SHOX2	9.24e-04	16	53	2	IPR003654
Domain	POU	POU4F1 POU4F2	1.05e-03	17	53	2	IPR013847
Domain	Homeobox_metazoa	HOXA9 GSX2 DLX2	2.13e-03	90	53	3	IPR020479
Domain	TF_DNA-bd	MAFB CREB5	4.94e-03	37	53	2	IPR008917
Pathway	WP_HEART_DEVELOPMENT	GATA6 HEY2 FOXC2	1.51e-04	46	32	3	MM15884
Pathway	WP_HEART_DEVELOPMENT	GATA6 HEY2 FOXC2	1.61e-04	47	32	3	M39610
Pathway	REACTOME_POU5F1_OCT4_SOX2_NANOG_REPRESS_GENES_RELATED_TO_DIFFERENTIATION	TSC22D1 GATA6	2.22e-04	10	32	2	M27208
Pathway	WP_ECTODERM_DIFFERENTIATION	TSC22D1 GATA6 MAFB NLK	2.85e-04	142	32	4	M39575
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS	POU4F1 POU4F2	4.47e-04	14	32	2	M27638
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY_THROUGH_ASSOCIATION_WITH_CO_FACTORS	POU4F1 POU4F2	4.47e-04	14	32	2	MM15341
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	FOXJ2 HOXA9 USP34 ONECUT2 GTF2A1 TSC22D1 PLK2 SENP1 VGLL3 OTX1 NKD1 RBM33 NUFIP2 AUTS2 CHD8 CBL ONECUT1 LRCH1 NONO PBXIP1 CREB5 NLK RNF111	7.90e-20	1203	54	23	29180619
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXJ2 HOXA9 ONECUT2 TSC22D1 OTX1 GATA6 HEY2 SHOX SHOX2 GSX2 MAFB POU4F1 POU4F2 DLX2 ONECUT1 CREB5 FOXF2 FOXC2	1.08e-15	908	54	18	19274049
Pubmed	The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor.	ONECUT2 GTF2A1 VGLL3 TMEM121B PRDM13 SHOX2 FOXC2	6.01e-14	33	54	7	19336002
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	FOXJ2 HOXA9 ONECUT2 OTX1 GATA6 HEY2 SHOX GSX2 POU4F1 DLX2 ONECUT1 CREB5 FOXC2	1.80e-12	544	54	13	28473536
Pubmed	Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development.	ONECUT2 POU4F1 POU4F2 ONECUT1	1.56e-08	18	54	4	25794677
Pubmed	The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo.	HOXA9 TSC22D1 GATA6 POU4F2 DLX2 ONECUT1 FOXC2	1.92e-08	191	54	7	24146773
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	FOXJ2 HOXA9 GTF2A1 GATA6 SHOX2 GSX2 MAFB POU4F1 POU4F2 DLX2 PBXIP1	8.77e-08	877	54	11	20211142
Pubmed	Onecut 1 and Onecut 2 are potential regulators of mouse retinal development.	ONECUT2 POU4F2 ONECUT1	1.97e-07	8	54	3	21830221
Pubmed	Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression.	PLK2 POU4F1 POU4F2 ONECUT1	2.32e-07	34	54	4	26949938
Pubmed	Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord.	ONECUT2 SHOX2 ONECUT1	4.21e-07	10	54	3	31231191
Pubmed	Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina.	POU4F1 POU4F2 DLX2	5.79e-07	11	54	3	28356311
Pubmed	Pou2f2 Regulates the Distribution of Dorsal Interneurons in the Mouse Developing Spinal Cord.	ONECUT2 POU4F1 ONECUT1	5.79e-07	11	54	3	31787878
Pubmed	Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development.	ONECUT2 POU4F1 POU4F2 ONECUT1	6.12e-07	43	54	4	25228773
Pubmed	Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program.	ONECUT2 MAFB ONECUT1	1.00e-06	13	54	3	22115757
Pubmed	Onecut transcription factors are required for the second phase of development of the A13 dopaminergic nucleus in the mouse.	ONECUT2 DLX2 ONECUT1	1.00e-06	13	54	3	22102297
Pubmed	The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration.	ONECUT2 GATA6 ONECUT1	1.27e-06	14	54	3	17936262
Pubmed	Precocious retinal neurons: Pax6 controls timing of differentiation and determination of cell type.	POU4F1 POU4F2 DLX2	1.27e-06	14	54	3	15733660
Pubmed	Onecut factors control development of the Locus Coeruleus and of the mesencephalic trigeminal nucleus.	ONECUT2 POU4F1 ONECUT1	1.27e-06	14	54	3	22534286
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	FOXJ2 ZCCHC14 GTF2A1 OTX1 GATA6 CBL ONECUT1 RNF111 FOXC2	1.36e-06	709	54	9	22988430
Pubmed	Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression.	ONECUT2 POU4F1 POU4F2 ONECUT1	1.44e-06	53	54	4	27210758
Pubmed	Dlx1 and Dlx2 function is necessary for terminal differentiation and survival of late-born retinal ganglion cells in the developing mouse retina.	POU4F1 POU4F2 DLX2	1.59e-06	15	54	3	15604100
Pubmed	Integral bHLH factor regulation of cell cycle exit and RGC differentiation.	ONECUT2 POU4F1 POU4F2	1.59e-06	15	54	3	29770538
Pubmed	Functional equivalence of Brn3 POU-domain transcription factors in mouse retinal neurogenesis.	POU4F1 POU4F2 DLX2	1.95e-06	16	54	3	15647317
Pubmed	The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development.	ONECUT2 POU4F1 ONECUT1	1.95e-06	16	54	3	28603487
Pubmed	Brn3a and Brn3b knockout mice display unvaried retinal fine structure despite major morphological and numerical alterations of ganglion cells.	POU4F1 POU4F2	2.37e-06	2	54	2	27391320
Pubmed	Short isoform of POU factor Brn-3b can form a heterodimer with Brn-3a that is inactive for octamer motif binding.	POU4F1 POU4F2	2.37e-06	2	54	2	8537352
Pubmed	Brn3 transcription factors control terminal osteoclastogenesis.	POU4F1 POU4F2	2.37e-06	2	54	2	17668438
Pubmed	Mouse forkhead (winged helix) gene LUN encodes a transactivator that acts in the lung.	FOXF2 FOXC2	2.37e-06	2	54	2	9676429
Pubmed	Comparative transgenic analysis of enhancers from the human SHOX and mouse Shox2 genomic regions.	SHOX SHOX2	2.37e-06	2	54	2	23575226
Pubmed	Inhibition of neuronal process outgrowth and neuronal specific gene activation by the Brn-3b transcription factor.	POU4F1 POU4F2	2.37e-06	2	54	2	8995448
Pubmed	Differential expression of four members of the POU family of proteins in activated and phorbol 12-myristate 13-acetate-treated Jurkat T cells.	POU4F1 POU4F2	2.37e-06	2	54	2	8234287
Pubmed	The homeobox transcription factor HOXA9 is a regulator of SHOX in U2OS cells and chicken micromass cultures.	HOXA9 SHOX	2.37e-06	2	54	2	23028966
Pubmed	CHF1/Hey2 suppresses SM-MHC promoter activity through an interaction with GATA-6.	GATA6 HEY2	2.37e-06	2	54	2	16293227
Pubmed	Dose-dependent regulation of horizontal cell fate by Onecut family of transcription factors.	ONECUT2 ONECUT1	2.37e-06	2	54	2	32790713
Pubmed	Expressing human SHOX in Shox2SHOX KI/KI mice leads to congenital osteoarthritis‑like disease of the temporomandibular joint in postnatal mice.	SHOX SHOX2	2.37e-06	2	54	2	27601064
Pubmed	A single amino acid change converts an inhibitory transcription factor into an activator.	POU4F1 POU4F2	2.37e-06	2	54	2	8662774
Pubmed	Autoregulatory sequences are revealed by complex stability screening of the mouse brn-3.0 locus.	POU4F1 POU4F2	2.37e-06	2	54	2	10414983
Pubmed	Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid.	POU4F1 POU4F2	2.37e-06	2	54	2	7904822
Pubmed	NT-3 regulates expression of Brn3a but not Brn3b in developing mouse trigeminal sensory neurons.	POU4F1 POU4F2	2.37e-06	2	54	2	9582431
Pubmed	Differential expression and subcellular localization of Copines in mouse retina.	POU4F1 POU4F2	2.37e-06	2	54	2	30866042
Pubmed	A cis-regulatory module underlies retinal ganglion cell genesis and axonogenesis.	ONECUT2 POU4F1 POU4F2	2.37e-06	17	54	3	38823017
Pubmed	Directed Bmp4 expression in neural crest cells generates a genetic model for the rare human bony syngnathia birth defect.	SHOX2 DLX2 FOXC2	2.37e-06	17	54	3	24785830
Pubmed	Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits.	ONECUT2 SHOX2 ONECUT1	2.84e-06	18	54	3	31969659
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	FOXJ2 HOXA9 OTX1 SHOX2 ONECUT1 FOXF2	3.37e-06	263	54	6	20932939
Pubmed	Onecut1 is essential for horizontal cell genesis and retinal integrity.	ONECUT2 POU4F2 ONECUT1	4.61e-06	21	54	3	23926259
Pubmed	Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity.	PRDM13 POU4F1 POU4F2	4.61e-06	21	54	3	25995483
Pubmed	Multiple requirements for Hes 1 during early eye formation.	POU4F1 POU4F2 DLX2	5.34e-06	22	54	3	16038893
Pubmed	Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity.	ONECUT2 MAFB ONECUT1	5.34e-06	22	54	3	38160393
Pubmed	Cis-Repression of Foxq1 Expression Affects Foxf2-Mediated Gene Expression in Palate Development.	SHOX2 CREB5 FOXF2	6.13e-06	23	54	3	33898467
Pubmed	Brn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expression.	POU4F1 POU4F2	7.09e-06	3	54	2	17145718
Pubmed	Role of the Brn-3 family of POU-domain genes in the development of the auditory/vestibular, somatosensory, and visual systems.	POU4F1 POU4F2	7.09e-06	3	54	2	9598366
Pubmed	Association of Catsper1 or -2 with Ca(v)3.3 leads to suppression of T-type calcium channel activity.	CATSPER1 CACNA1I	7.09e-06	3	54	2	16740636
Pubmed	Transcription factor GATA6: a novel marker and putative inducer of ductal metaplasia in biliary atresia.	GATA6 ONECUT1	7.09e-06	3	54	2	29388792
Pubmed	No association between POU4F1, POU4F2, ISL1 polymorphisms and normal-tension glaucoma.	POU4F1 POU4F2	7.09e-06	3	54	2	32597291
Pubmed	Differential expression of Brn3 transcription factors in intrinsically photosensitive retinal ganglion cells in mouse.	POU4F1 POU4F2	7.09e-06	3	54	2	21935940
Pubmed	OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6.	ONECUT2 ONECUT1	7.09e-06	3	54	2	9915796
Pubmed	Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a.	POU4F1 POU4F2	7.09e-06	3	54	2	8290353
Pubmed	Doppel expression is regulated by the Brn-3a and Brn-3b transcription factors.	POU4F1 POU4F2	7.09e-06	3	54	2	15094508
Pubmed	The Brn-3 family of POU-domain factors: primary structure, binding specificity, and expression in subsets of retinal ganglion cells and somatosensory neurons.	POU4F1 POU4F2	7.09e-06	3	54	2	7623109
Pubmed	Systematic identification of intergenic long-noncoding RNAs in mouse retinas using full-length isoform sequencing.	POU4F1 POU4F2	7.09e-06	3	54	2	31286854
Pubmed	OC-3, a novel mammalian member of the ONECUT class of transcription factors.	ONECUT2 ONECUT1	7.09e-06	3	54	2	11944891
Pubmed	Pou4f1 and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice.	POU4F1 POU4F2	7.09e-06	3	54	2	24736625
Pubmed	Pou4f2-GFP knock-in mouse line: A model for studying retinal ganglion cell development.	POU4F1 POU4F2	7.09e-06	3	54	2	27532212
Pubmed	The opposite and antagonistic effects of the closely related POU family transcription factors Brn-3a and Brn-3b on the activity of a target promoter are dependent on differences in the POU domain.	POU4F1 POU4F2	7.09e-06	3	54	2	7935408
Pubmed	ONECUT transcription factors induce neuronal characteristics and remodel chromatin accessibility.	ONECUT2 ONECUT1	7.09e-06	3	54	2	31049588
Pubmed	POU transcription factors Brn-3a and Brn-3b interact with the estrogen receptor and differentially regulate transcriptional activity via an estrogen response element.	POU4F1 POU4F2	7.09e-06	3	54	2	9448000
Pubmed	RBM33 is a unique m6A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity.	SENP1 RBM33	7.09e-06	3	54	2	37257451
Pubmed	Chromosomal localization and sequences of the murine Brn-3 family of developmental control genes.	POU4F1 POU4F2	7.09e-06	3	54	2	8162704
Pubmed	Dre - Cre sequential recombination provides new tools for retinal ganglion cell labeling and manipulation in mice.	POU4F1 POU4F2	7.09e-06	3	54	2	24608965
Pubmed	Distinct roles of transcription factors brn3a and brn3b in controlling the development, morphology, and function of retinal ganglion cells.	POU4F1 POU4F2	7.09e-06	3	54	2	19323995
Pubmed	Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate.	POU4F1 POU4F2 ONECUT1	7.94e-06	25	54	3	25775587
Pubmed	Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord.	ONECUT2 SHOX2 ONECUT1	8.97e-06	26	54	3	28082864
Pubmed	Notch signaling controls liver development by regulating biliary differentiation.	ONECUT2 HEY2 ONECUT1	8.97e-06	26	54	3	19369401
Pubmed	Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease.	ZCCHC14 SKIDA1 AUTS2	1.13e-05	28	54	3	33953184
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	USP34 GTF2A1 TSC22D1 RBM33 FAM120C CPEB4 CHD8 CBL NONO PBXIP1 CREB5	1.18e-05	1451	54	11	30550785
Pubmed	Single-cell transcriptional logic of cell-fate specification and axon guidance in early-born retinal neurons.	ONECUT2 POU4F1 POU4F2	1.39e-05	30	54	3	31399471
Pubmed	Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.	ONECUT2 POU4F1 POU4F2	1.39e-05	30	54	3	30127719
Pubmed	Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation.	ONECUT2 POU4F1 POU4F2	1.39e-05	30	54	3	29137925
Pubmed	Essential role of POU-domain factor Brn-3c in auditory and vestibular hair cell development.	POU4F1 POU4F2	1.42e-05	4	54	2	9256502
Pubmed	Identification of retinal ganglion cell types and brain nuclei expressing the transcription factor Brn3c/Pou4f3 using a Cre recombinase knock-in allele.	POU4F1 POU4F2	1.42e-05	4	54	2	33135183
Pubmed	Expression of the alpha7 isoform of hepatocyte nuclear factor (HNF) 4 is activated by HNF6/OC-2 and HNF1 and repressed by HNF4alpha1 in the liver.	ONECUT2 ONECUT1	1.42e-05	4	54	2	15159395
Pubmed	Morphologies of mouse retinal ganglion cells expressing transcription factors Brn3a, Brn3b, and Brn3c: analysis of wild type and mutant cells using genetically-directed sparse labeling.	POU4F1 POU4F2	1.42e-05	4	54	2	20826176
Pubmed	Cloning and embryonic expression pattern of the mouse Onecut transcription factor OC-2.	ONECUT2 ONECUT1	1.42e-05	4	54	2	12971999
Pubmed	Aberrant expression of HOXA9, DEK, CBL and CSF1R in acute myeloid leukemia.	HOXA9 CBL	1.42e-05	4	54	2	14738146
Pubmed	Conditional MN1-TEL knock-in mice develop acute myeloid leukemia in conjunction with overexpression of HOXA9.	HOXA9 MN1	1.42e-05	4	54	2	16105979
Pubmed	Foxc transcription factors directly regulate Dll4 and Hey2 expression by interacting with the VEGF-Notch signaling pathways in endothelial cells.	HEY2 FOXC2	1.42e-05	4	54	2	18545664
Pubmed	Genetic interactions between Brn3 transcription factors in retinal ganglion cell type specification.	POU4F1 POU4F2	1.42e-05	4	54	2	24116103
Pubmed	Discrete gene sets depend on POU domain transcription factor Brn3b/Brn-3.2/POU4f2 for their expression in the mouse embryonic retina.	POU4F1 POU4F2 DLX2	1.70e-05	32	54	3	14973295
Pubmed	A cellular and molecular mosaic establishes growth and differentiation states for cranial sensory neurons.	ONECUT2 POU4F1 ONECUT1	2.24e-05	35	54	3	26988119
Pubmed	Functional redundancy between human SHOX and mouse Shox2 genes in the regulation of sinoatrial node formation and pacemaking function.	SHOX SHOX2	2.36e-05	5	54	2	21454626
Pubmed	Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression.	POU4F1 POU4F2	2.36e-05	5	54	2	18368538
Pubmed	Polymorphisms of coding trinucleotide repeats of homeogenes in neurodevelopmental psychiatric disorders.	OTX1 DLX2	2.36e-05	5	54	2	19018235
Pubmed	MiR-495 and miR-218 regulate the expression of the Onecut transcription factors HNF-6 and OC-2.	ONECUT2 ONECUT1	2.36e-05	5	54	2	19913497
Pubmed	Multiomic Analysis of Neurons with Divergent Projection Patterns Identifies Novel Regulators of Axon Pathfinding.	POU4F1 POU4F2	2.36e-05	5	54	2	35988153
Pubmed	Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3.	GATA6 CBL	2.36e-05	5	54	2	32145025
Pubmed	New mouse lines for the analysis of neuronal morphology using CreER(T)/loxP-directed sparse labeling.	POU4F1 POU4F2	2.36e-05	5	54	2	19924248
Pubmed	Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development.	POU4F1 POU4F2	2.36e-05	5	54	2	8637595
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ZCCHC14 USP34 AUTS2 CHD8 LRCH1	2.65e-05	225	54	5	12168954
Pubmed	A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain.	ONECUT2 MAFB POU4F1	2.87e-05	38	54	3	39106860
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	FOXJ2 ZCCHC14 ONECUT2 GTF2A1 TSC22D1 OTX1 GATA6 ONECUT1	3.32e-05	808	54	8	20412781
Interaction	RNF4 interactions	FOXJ2 HOXA9 USP34 ONECUT2 GTF2A1 TSC22D1 PLK2 SENP1 VGLL3 OTX1 NKD1 RBM33 NUFIP2 AUTS2 GSX2 CHD8 CBL ONECUT1 LRCH1 NONO PBXIP1 CREB5 NLK RNF111	1.75e-14	1412	53	24	int:RNF4
Interaction	KRTAP4-2 interactions	VGLL3 OTX1 CATSPER1 NUFIP2 MAFB POU4F2 CREB5 NLK	1.89e-09	132	53	8	int:KRTAP4-2
Interaction	KRTAP5-9 interactions	OTX1 CATSPER1 NKD1 NUFIP2 HEY2 POU4F2 CREB5 NLK RNF111	2.70e-09	203	53	9	int:KRTAP5-9
Interaction	KRTAP5-6 interactions	VGLL3 OTX1 CATSPER1 NUFIP2 POU4F2 CREB5 NLK	4.95e-09	94	53	7	int:KRTAP5-6
Interaction	KRTAP10-1 interactions	HOXA9 OTX1 CATSPER1 NKD1 NUFIP2 POU4F2 CREB5 NLK	6.09e-09	153	53	8	int:KRTAP10-1
Interaction	KDM5B interactions	ONECUT2 GTF2A1 VGLL3 TMEM121B PRDM13 SHOX2 FOXC2	7.65e-09	100	53	7	int:KDM5B
Interaction	KRTAP9-8 interactions	VGLL3 OTX1 CATSPER1 NKD1 NUFIP2 POU4F2 CREB5	7.65e-09	100	53	7	int:KRTAP9-8
Interaction	FBLN5 interactions	SENP1 OTX1 NUFIP2 HRG CHD8 CREB5 FOXF2 RNF111	8.25e-09	159	53	8	int:FBLN5
Interaction	KRTAP5-11 interactions	VGLL3 OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	1.99e-08	66	53	6	int:KRTAP5-11
Interaction	KRTAP4-4 interactions	OTX1 CATSPER1 NUFIP2 HEY2 POU4F2 CREB5	6.90e-08	81	53	6	int:KRTAP4-4
Interaction	KRTAP9-3 interactions	HOXA9 VGLL3 OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	7.93e-08	140	53	7	int:KRTAP9-3
Interaction	LGALS13 interactions	OTX1 NUFIP2 POU4F2 CREB5	9.89e-08	17	53	4	int:LGALS13
Interaction	KRTAP1-1 interactions	VGLL3 OTX1 CATSPER1 NUFIP2 HEY2 POU4F2 CREB5 RNF111	9.96e-08	219	53	8	int:KRTAP1-1
Interaction	KRTAP12-3 interactions	VGLL3 OTX1 CATSPER1 NKD1 NUFIP2 POU4F2 CREB5	1.06e-07	146	53	7	int:KRTAP12-3
Interaction	KRTAP4-11 interactions	VGLL3 OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	1.48e-07	92	53	6	int:KRTAP4-11
Interaction	KRTAP6-1 interactions	VGLL3 OTX1 CATSPER1 HEY2 POU4F2 CREB5	2.91e-07	103	53	6	int:KRTAP6-1
Interaction	KRTAP5-4 interactions	OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	6.49e-07	63	53	5	int:KRTAP5-4
Interaction	KRTAP10-11 interactions	OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	7.03e-07	64	53	5	int:KRTAP10-11
Interaction	CYSRT1 interactions	ZCCHC14 VGLL3 OTX1 CATSPER1 NKD1 NUFIP2 HEY2 HRG POU4F2 CREB5	7.37e-07	511	53	10	int:CYSRT1
Interaction	KRTAP5-3 interactions	OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	8.21e-07	66	53	5	int:KRTAP5-3
Interaction	KRTAP4-1 interactions	OTX1 CATSPER1 NUFIP2 CREB5	1.27e-06	31	53	4	int:KRTAP4-1
Interaction	KRTAP9-4 interactions	OTX1 CATSPER1 NUFIP2 CREB5	1.65e-06	33	53	4	int:KRTAP9-4
Interaction	KRTAP3-2 interactions	OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	2.02e-06	79	53	5	int:KRTAP3-2
Interaction	KRTAP19-6 interactions	VGLL3 OTX1 CATSPER1 POU4F2 CREB5	2.02e-06	79	53	5	int:KRTAP19-6
Interaction	TRIM42 interactions	VGLL3 OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	2.55e-06	149	53	6	int:TRIM42
Interaction	KRTAP9-2 interactions	VGLL3 OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	2.55e-06	149	53	6	int:KRTAP9-2
Interaction	RGS19 interactions	OTX1 CATSPER1 NUFIP2 POU4F2	2.64e-06	37	53	4	int:RGS19
Interaction	KRTAP10-9 interactions	VGLL3 OTX1 CATSPER1 NKD1 NUFIP2 POU4F2 CREB5	3.09e-06	241	53	7	int:KRTAP10-9
Interaction	LCE2C interactions	OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	3.44e-06	88	53	5	int:LCE2C
Interaction	LCE1F interactions	OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	4.29e-06	92	53	5	int:LCE1F
Interaction	CHRD interactions	OTX1 CATSPER1 NUFIP2 HRG POU4F2	4.77e-06	94	53	5	int:CHRD
Interaction	KRTAP2-3 interactions	OTX1 CATSPER1 NKD1 NUFIP2 CREB5	5.02e-06	95	53	5	int:KRTAP2-3
Interaction	KRTAP2-4 interactions	OTX1 CATSPER1 NKD1 NUFIP2 CREB5	6.78e-06	101	53	5	int:KRTAP2-4
Interaction	KRTAP19-2 interactions	VGLL3 OTX1 POU4F2 CREB5	6.99e-06	47	53	4	int:KRTAP19-2
Interaction	KRTAP1-5 interactions	OTX1 CATSPER1 NUFIP2 CREB5	7.61e-06	48	53	4	int:KRTAP1-5
Interaction	KRTAP6-2 interactions	VGLL3 OTX1 CATSPER1 HEY2 CREB5 SIAH3	9.41e-06	187	53	6	int:KRTAP6-2
Interaction	PCSK5 interactions	VGLL3 OTX1 NUFIP2 POU4F2 CREB5	1.12e-05	112	53	5	int:PCSK5
Interaction	TSPAN4 interactions	VGLL3 OTX1 CATSPER1 CREB5	1.13e-05	53	53	4	int:TSPAN4
Interaction	RGS20 interactions	OTX1 CATSPER1 NUFIP2 HRG CREB5	1.45e-05	118	53	5	int:RGS20
Interaction	MDFI interactions	VGLL3 OTX1 CATSPER1 NKD1 NUFIP2 PBXIP1 CREB5 RNF111	1.54e-05	430	53	8	int:MDFI
Interaction	KRTAP12-1 interactions	VGLL3 OTX1 CATSPER1 POU4F2	2.26e-05	63	53	4	int:KRTAP12-1
Interaction	EGLN3 interactions	FOXJ2 ZCCHC14 USP34 SENP1 VGLL3 RBM33 CPEB4 GATA6 CHD8 MTCL1 CBL LRCH1 CREB5	2.27e-05	1296	53	13	int:EGLN3
Interaction	RBPMS interactions	HOXA9 VGLL3 OTX1 HEY2 POU4F2 CREB5 FOXC2	2.89e-05	340	53	7	int:RBPMS
Interaction	KRTAP4-5 interactions	OTX1 NUFIP2 POU4F2 CREB5	4.75e-05	76	53	4	int:KRTAP4-5
Interaction	SPRY2 interactions	OTX1 CATSPER1 NUFIP2 CBL CREB5	4.90e-05	152	53	5	int:SPRY2
Interaction	LCE4A interactions	OTX1 NUFIP2 CREB5 RNF111	5.81e-05	80	53	4	int:LCE4A
Interaction	DLX5 interactions	FOXJ2 DLX2 FOXC2	5.98e-05	29	53	3	int:DLX5
Interaction	KRTAP10-5 interactions	OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	6.25e-05	160	53	5	int:KRTAP10-5
Interaction	KRTAP3-3 interactions	VGLL3 OTX1 NUFIP2 FOXC2	6.41e-05	82	53	4	int:KRTAP3-3
Interaction	KRTAP4-12 interactions	OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	6.44e-05	161	53	5	int:KRTAP4-12
Interaction	PRR22 interactions	VGLL3 OTX1 CREB5	6.63e-05	30	53	3	int:PRR22
Interaction	KRTAP3-1 interactions	VGLL3 OTX1 HEY2 CREB5	7.37e-05	85	53	4	int:KRTAP3-1
Interaction	SPRY4 interactions	OTX1 POU4F2 CBL CREB5	7.72e-05	86	53	4	int:SPRY4
Interaction	KRTAP10-8 interactions	VGLL3 OTX1 CATSPER1 NKD1 NUFIP2 POU4F2 CREB5	8.21e-05	401	53	7	int:KRTAP10-8
Interaction	PLSCR1 interactions	HOXA9 CATSPER1 NUFIP2 HEY2 HRG	8.80e-05	172	53	5	int:PLSCR1
Interaction	CYP21A2 interactions	NUFIP2 POU4F2 CREB5	8.86e-05	33	53	3	int:CYP21A2
Interaction	LCE5A interactions	CATSPER1 NUFIP2 POU4F2 CREB5	9.21e-05	90	53	4	int:LCE5A
Interaction	GRN interactions	OTX1 NUFIP2 HRG POU4F2 DLX2 NLK	9.23e-05	281	53	6	int:GRN
Interaction	KPRP interactions	VGLL3 OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	9.78e-05	284	53	6	int:KPRP
Interaction	KRTAP10-7 interactions	VGLL3 OTX1 CATSPER1 NKD1 NUFIP2 CREB5	1.16e-04	293	53	6	int:KRTAP10-7
Interaction	CDPF1 interactions	VGLL3 CATSPER1 CREB5	1.25e-04	37	53	3	int:CDPF1
Interaction	FHL5 interactions	OTX1 CATSPER1 NUFIP2 HEY2	1.50e-04	102	53	4	int:FHL5
Interaction	CSTF2T interactions	FOXJ2 CPEB4 NUFIP2 NONO	1.67e-04	105	53	4	int:CSTF2T
Interaction	KRTAP11-1 interactions	VGLL3 OTX1 NUFIP2 HEY2	1.87e-04	108	53	4	int:KRTAP11-1
Interaction	SP100 interactions	SENP1 FAM120C NUFIP2 MAFB NONO	2.05e-04	206	53	5	int:SP100
Interaction	SPRY1 interactions	OTX1 HRG CBL CREB5	2.07e-04	111	53	4	int:SPRY1
Interaction	BACH1 interactions	MAFB CHD8 CREB5 NLK	2.07e-04	111	53	4	int:BACH1
Interaction	PLA2G10 interactions	VGLL3 OTX1 CATSPER1 CREB5	2.22e-04	113	53	4	int:PLA2G10
Interaction	KRTAP19-7 interactions	VGLL3 OTX1 CATSPER1 POU4F2	2.54e-04	117	53	4	int:KRTAP19-7
Interaction	ADAMTSL4 interactions	OTX1 CATSPER1 NUFIP2 POU4F2 CREB5	2.61e-04	217	53	5	int:ADAMTSL4
Interaction	RGS17 interactions	OTX1 NUFIP2 CREB5	2.73e-04	48	53	3	int:RGS17
Interaction	FRS3 interactions	VGLL3 CATSPER1 CBL CREB5	2.98e-04	122	53	4	int:FRS3
Interaction	CERCAM interactions	VGLL3 OTX1 POU4F2 CREB5	2.98e-04	122	53	4	int:CERCAM
Interaction	ALPP interactions	OTX1 NUFIP2 POU4F2 CREB5	3.07e-04	123	53	4	int:ALPP
Interaction	ALOXE3 interactions	PLK2 NONO RNF111	3.47e-04	52	53	3	int:ALOXE3
Interaction	KRTAP12-2 interactions	VGLL3 OTX1 CATSPER1 POU4F2	3.57e-04	128	53	4	int:KRTAP12-2
Interaction	NBPF19 interactions	OTX1 CATSPER1 NUFIP2 CREB5 RNF111	3.61e-04	233	53	5	int:NBPF19
Interaction	KRTAP10-4 interactions	OTX1 CATSPER1	4.40e-04	12	53	2	int:KRTAP10-4
Interaction	EFEMP2 interactions	OTX1 CATSPER1 NUFIP2 CREB5	4.50e-04	136	53	4	int:EFEMP2
Interaction	DAZL interactions	RBM33 FAM120C CPEB4 NUFIP2	5.73e-04	145	53	4	int:DAZL
Interaction	VWC2 interactions	OTX1 CATSPER1 POU4F2	5.82e-04	62	53	3	int:VWC2
Interaction	CFD interactions	USP34 GTF2A1 TSC22D1 RBM33 FAM120C CPEB4 CHD8 CBL NONO PBXIP1 CREB5	6.96e-04	1360	53	11	int:CFD
Interaction	KRTAP22-1 interactions	OTX1 CREB5	6.97e-04	15	53	2	int:KRTAP22-1
Interaction	SERPINB7 interactions	PLK2 HEY2 NONO	7.63e-04	68	53	3	int:SERPINB7
Interaction	KRTAP4-7 interactions	OTX1 CATSPER1	7.95e-04	16	53	2	int:KRTAP4-7
Interaction	PLSCR2 interactions	OTX1 POU4F2	7.95e-04	16	53	2	int:PLSCR2
Interaction	KRTAP6-3 interactions	OTX1 AUTS2 POU4F2 CREB5	8.47e-04	161	53	4	int:KRTAP6-3
Interaction	CHIC2 interactions	OTX1 CATSPER1 POU4F2	9.38e-04	73	53	3	int:CHIC2
Interaction	ESRP2 interactions	FAM120C FOXF2 RNF111	9.76e-04	74	53	3	int:ESRP2
Interaction	CNFN interactions	VGLL3 CREB5	1.01e-03	18	53	2	int:CNFN
Interaction	KRTAP10-3 interactions	OTX1 CATSPER1 NUFIP2 CREB5 NLK	1.03e-03	294	53	5	int:KRTAP10-3
Interaction	LCE1C interactions	OTX1 POU4F2 CREB5	1.10e-03	77	53	3	int:LCE1C
Interaction	UBAP2L interactions	ZCCHC14 FAM120C CPEB4 NUFIP2 NLK	1.10e-03	298	53	5	int:UBAP2L
Interaction	C11orf68 interactions	MTCL1 NONO	1.13e-03	19	53	2	int:C11orf68
Interaction	TSG101 interactions	FAM120C NUFIP2 CBL NONO RNF111	1.18e-03	303	53	5	int:TSG101
Interaction	COMP interactions	OTX1 NUFIP2	1.25e-03	20	53	2	int:COMP
Interaction	RBP3 interactions	POU4F2 CREB5	1.25e-03	20	53	2	int:RBP3
Interaction	FNDC5 interactions	USP34 GTF2A1 TSC22D1 RBM33 FAM120C CPEB4 CHD8 CBL NONO PBXIP1 CREB5	1.32e-03	1470	53	11	int:FNDC5
Interaction	ESM1 interactions	VGLL3 NUFIP2	1.38e-03	21	53	2	int:ESM1
Interaction	KRTAP1-3 interactions	OTX1 CATSPER1 NUFIP2 CREB5	1.39e-03	184	53	4	int:KRTAP1-3
Cytoband	Ensembl 112 genes in cytogenetic band chr2p15	USP34 OTX1	1.24e-03	44	54	2	chr2p15
Cytoband	Ensembl 112 genes in cytogenetic band chr13q14	TSC22D1 LRCH1 SIAH3	3.01e-03	244	54	3	chr13q14
GeneFamily	Forkhead boxes	FOXJ2 FOXF2 FOXC2	7.78e-05	43	35	3	508
GeneFamily	CUT class homeoboxes and pseudogenes	ONECUT2 ONECUT1	1.30e-04	9	35	2	527
GeneFamily	PRD class homeoboxes and pseudogenes	OTX1 SHOX SHOX2	7.42e-04	92	35	3	521
GeneFamily	POU class homeoboxes and pseudogenes	POU4F1 POU4F2	8.98e-04	23	35	2	523
GeneFamily	Basic leucine zipper proteins	MAFB CREB5	4.04e-03	49	35	2	506
GeneFamily	HOXL subclass homeoboxes	HOXA9 GSX2	4.54e-03	52	35	2	518
GeneFamily	RNA binding motif containing	RBM33 CPEB4 NONO	8.00e-03	213	35	3	725
Coexpression	BENPORATH_EED_TARGETS	HOXA9 ZCCHC14 ONECUT2 OTX1 GATA6 AUTS2 PRDM13 SHOX SHOX2 GSX2 MAFB POU4F1 POU4F2 DLX2 ONECUT1 FOXF2	2.24e-10	1059	54	16	M7617
Coexpression	BENPORATH_ES_WITH_H3K27ME3	HOXA9 ONECUT2 OTX1 GATA6 PRDM13 SHOX SHOX2 GSX2 MAFB POU4F1 POU4F2 DLX2 ONECUT1 FOXF2	3.87e-08	1115	54	14	M10371
Coexpression	BENPORATH_PRC2_TARGETS	ONECUT2 OTX1 GATA6 SHOX SHOX2 GSX2 MAFB POU4F1 POU4F2 DLX2 ONECUT1	7.29e-08	650	54	11	M8448
Coexpression	BENPORATH_SUZ12_TARGETS	ONECUT2 OTX1 NKD1 GATA6 SHOX SHOX2 GSX2 MAFB POU4F1 POU4F2 DLX2 ONECUT1 SIAH3	1.29e-07	1035	54	13	M9898
Coexpression	RORIE_TARGETS_OF_EWSR1_FLI1_FUSION_UP	SELENOP POU4F1 DLX2 MN1	3.17e-07	28	54	4	M3169
Coexpression	GSE41978_ID2_KO_AND_BIM_KO_VS_BIM_KO_KLRG1_LOW_EFFECTOR_CD8_TCELL_DN	ZCCHC14 USP34 TSC22D1 HEY2 AUTS2 CBL	3.39e-06	199	54	6	M9567
Coexpression	PEREZ_TP63_TARGETS	SELENOP GATA6 HEY2 AUTS2 MAFB DLX2 FOXF2	8.23e-06	356	54	7	M10761
Coexpression	CUI_TCF21_TARGETS_2_DN	GTF2A1 VGLL3 CPEB4 HEY2 MAFB MTCL1 CBL LRCH1 NLK FOXC2	8.34e-06	854	54	10	M1533
Coexpression	CUI_TCF21_TARGETS_2_DN	GTF2A1 VGLL3 CPEB4 HEY2 MAFB MTCL1 CBL LRCH1 NLK FOXC2	1.17e-05	888	54	10	MM1018
Coexpression	WANG_MLL_TARGETS	SELENOP GATA6 SHOX2 MAFB DLX2 FOXC2	3.11e-05	294	54	6	M2456
Coexpression	MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	NKD1 FBXO41 PRDM13 GSX2 MAFB CACNA1I FOXC2	3.12e-05	438	54	7	M1954
Coexpression	MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	NKD1 FBXO41 PRDM13 GSX2 MAFB CACNA1I FOXC2	3.21e-05	440	54	7	MM832
Coexpression	BURTON_ADIPOGENESIS_1	TSC22D1 DLX2 FOXC2	3.57e-05	31	54	3	M1612
Coexpression	BURTON_ADIPOGENESIS_1	TSC22D1 DLX2 FOXC2	3.57e-05	31	54	3	MM1191
Coexpression	WANG_MLL_TARGETS	SELENOP GATA6 SHOX2 MAFB DLX2 FOXC2	3.89e-05	306	54	6	MM1076
Coexpression	GSE22886_UNSTIM_VS_IL2_STIM_NKCELL_UP	ZCCHC14 SELENOP TSC22D1 SHOX2 PBXIP1	5.22e-05	196	54	5	M4530
Coexpression	GSE32423_CTRL_VS_IL7_MEMORY_CD8_TCELL_UP	NKD1 SYT3 FBXO41 SHOX2 CREB5	5.48e-05	198	54	5	M5083
Coexpression	GSE42724_NAIVE_VS_MEMORY_BCELL_DN	SELENOP CPEB4 SHOX2 LRCH1 NONO	5.74e-05	200	54	5	M9793
Coexpression	GSE21774_CD62L_POS_CD56_BRIGHT_VS_CD62L_NEG_CD56_DIM_NK_CELL_DN	TSC22D1 RBM33 FAM120C NUFIP2 NLK	5.74e-05	200	54	5	M7495
Coexpression	GSE2405_0H_VS_1.5H_A_PHAGOCYTOPHILUM_STIM_NEUTROPHIL_UP	SELENOP NKD1 AUTS2 HRC MAFB	5.74e-05	200	54	5	M6209
Coexpression	AMIT_SERUM_RESPONSE_60_MCF10A	PLK2 VGLL3 MAFB	2.35e-04	58	54	3	M3447
Coexpression	STK33_SKM_UP	ZCCHC14 PLK2 CPEB4 MAFB CREB5	2.72e-04	279	54	5	M2857
Coexpression	MANNO_MIDBRAIN_NEUROTYPES_HRGL2B	SELENOP C21orf58 HEY2 PRDM13 PBXIP1 CREB5	2.79e-04	439	54	6	M39054
Coexpression	RUIZ_TNC_TARGETS_UP	SELENOP PLK2 MAFB FOXF2	3.03e-04	156	54	4	M988
CoexpressionAtlas	ratio_EmbryoidBody_vs_StemCell_top-relative-expression-ranked_2500_k-means-cluster#3	ONECUT2 SELENOP OTX1 NKD1 SHOX2 GSX2 POU4F1 DLX2 MN1 FOXF2 FOXC2	6.69e-05	1094	53	11	ratio_EB_vs_SC_2500_K3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#4_top-relative-expression-ranked_100	SHOX2 DLX2 FOXF2	6.92e-05	32	53	3	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_100_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000	ZCCHC14 VGLL3 NKD1 HEY2 AUTS2 SHOX2 DLX2 CBL FOXF2	1.08e-04	769	53	9	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000	HOXA9 ONECUT2 NKD1 HRC SHOX2 MAFB POU4F1 DLX2 ONECUT1 FOXF2	1.41e-04	986	53	10	PCBC_EB_fibroblast_1000
CoexpressionAtlas	Progenitor-Cell-Biology-Consortium_EmbryoidBody_top-relative-expression-ranked_1000	HOXA9 ONECUT2 NKD1 SYT3 HRC SHOX2 POU4F1 DLX2 ONECUT1 FOXF2	1.50e-04	994	53	10	PCBC_EB_1000
CoexpressionAtlas	DevelopingGonad_e11.5_ovary + mesonephros_emap-3226_top-relative-expression-ranked_1000	ONECUT2 GTF2A1 SENP1 CPEB4 SHOX2 CHD8 CBL NONO FOXC2	1.68e-04	815	53	9	gudmap_developingGonad_e11.5_ovary + mesonephros_1000
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Immature_Interneurons\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	ONECUT2 SELENOP GSX2 MAFB DLX2	2.34e-06	176	54	5	62870115e31170c8b42eec57c709e0fe32388b37
ToppCell	Pericytes-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	HOXA9 NKD1 HEY2 SHOX2 FOXC2	2.48e-06	178	54	5	a2448d868da2abe48c394c51264aad03e866dfec
ToppCell	Pericytes-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	NKD1 HEY2 HRC MN1 FOXC2	2.76e-06	182	54	5	46c213597445b1f4f09dc367f27702d24b201daf
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZCCHC14 TSC22D1 GATA6 HEY2 FOXC2	3.07e-06	186	54	5	1e67bfb248366d7395efdd2d5e70a97bdb2e68af
ToppCell	Pericytes-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	NKD1 HEY2 HRC FOXF2 FOXC2	3.15e-06	187	54	5	35f25780d113f60bf4c13749013c09612ee4ff41
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VGLL3 HEY2 HRC FOXF2 FOXC2	3.77e-06	194	54	5	a7731378f44ca1a229311686caf5740c742d21ba
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VGLL3 HEY2 POU4F2 DLX2 CREB5	3.87e-06	195	54	5	9fea1ddb68da83ca43dd8006c9e51295b1817f0e
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	TSC22D1 PLK2 DLX2 MN1 SIAH3	4.37e-06	200	54	5	306926cb7a847871641f02e03d52dc56fd55711c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Interneuron\|1m / Sample Type, Dataset, Time_group, and Cell type.	ONECUT2 TMEM121B POU4F2 DLX2 ONECUT1	4.37e-06	200	54	5	fc839e9c33ea1d4ee0f42f21fd32a54e7cbe1f5a
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	TSC22D1 PLK2 DLX2 MN1	1.05e-05	112	54	4	9c3fb470708e76a8f8a3cb9aa17ab130c60fee11
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-1\|TCGA-Brain / Sample_Type by Project: Shred V9	OTX1 PRDM13 SHOX2 CREB5	1.66e-05	126	54	4	8b689886ce35ff798aea603cde9ccb0dc9d1fd03
ToppCell	E16.5-samps-Mesenchymal-Pericyte\|E16.5-samps / Age Group, Lineage, Cell class and subclass	C21orf58 HRCT1 HEY2 ONECUT1	3.13e-05	148	54	4	e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCell	E16.5-samps-Mesenchymal-Pericyte-pericyte_A\|E16.5-samps / Age Group, Lineage, Cell class and subclass	C21orf58 HRCT1 HEY2 ONECUT1	3.13e-05	148	54	4	c87fe2373418ec0cfe37279003d1c4df4c0d0aac
ToppCell	3'_v3-blood-Lymphocytic_T_CD8-Trm_gut_CD8\|blood / Manually curated celltypes from each tissue	GATA6 AUTS2 CACNA1I PRR7	3.47e-05	152	54	4	1fea735321da6db6d2cd3f83d2f7fac72d44904d
ToppCell	NS-moderate-d_07-13-Myeloid-Mast_cell\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	HOXA9 CATSPER1 NKD1 MTCL1	3.84e-05	156	54	4	17c38d3b03fc38cb125cf0d165b2fd694cd88edd
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ONECUT2 AUTS2 POU4F1 CCER2	4.35e-05	161	54	4	bd520c9a1927d5d5355b4421e6b90b58bfb76a42
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	HOXA9 TSC22D1 MN1 FOXC2	4.78e-05	165	54	4	7b992843bd8ef92a7a76b1d681fa84efde6f5bdd
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D122\|Adult / Lineage, Cell type, age group and donor	SELENOP TMEM121B MAFB CREB5	4.89e-05	166	54	4	be284e2e596390f05305c7bcfc316f87b963fc0b
ToppCell	3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Progenitor\|lymph-node_spleen / Manually curated celltypes from each tissue	HOXA9 ONECUT2 TSC22D1 MN1	5.01e-05	167	54	4	cb396f3edb9e8fdc316091e8e193dbba50e0be0c
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOP PLK2 SYT3 MAFB	5.49e-05	171	54	4	a474aaed3ca4cacb0ab565c35f25d92a10f531b7
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	HOXA9 CATSPER1 FAM120C AUTS2	5.62e-05	172	54	4	e3a8891694343b6b01e80a200ae338d24797e417
ToppCell	wk_08-11-Mesenchymal-Chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	TSC22D1 AUTS2 MAFB FOXC2	6.14e-05	176	54	4	1af28b701c4598ce761f85adbd5d79e4918d265a
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	SELENOP VGLL3 NKD1 FOXF2	6.28e-05	177	54	4	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SELENOP VGLL3 NKD1 FOXF2	6.28e-05	177	54	4	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HOXA9 TSC22D1 HEY2 HRC	6.42e-05	178	54	4	e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSC22D1 HRCT1 GATA6 HEY2	6.42e-05	178	54	4	9f59a9af232d77bb55603a7776dbf9749ea652f2
ToppCell	Striatum-Endothelial-MURAL\|Striatum / BrainAtlas - Mouse McCarroll V32	VGLL3 HRCT1 HEY2 HRC	6.56e-05	179	54	4	3d58babf44e47462c3d4129dd2e94a2339fd7ce0
ToppCell	wk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	HRCT1 HEY2 POU4F1 FOXC2	6.56e-05	179	54	4	8c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCell	Striatum-Endothelial-MURAL-M1(Rgs5Acta2)\|Striatum / BrainAtlas - Mouse McCarroll V32	VGLL3 HRCT1 HEY2 HRC	6.56e-05	179	54	4	99167ac678cae5c35b1d4f4a81b32000437c00c2
ToppCell	droplet-Kidney-nan-18m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NKD1 HEY2 HRC FOXC2	6.70e-05	180	54	4	b6f44fdedc33b7d93b0074e8e9c8cc32009d4c4d
ToppCell	wk_08-11-Mesenchymal-Chondrocyte-ASPN+_chondrocyte\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	AUTS2 MAFB CCER2 FOXC2	7.00e-05	182	54	4	0e52ba34e179d9bfaac7b49920b44c710b2b8dad
ToppCell	Cerebellum-Endothelial-MURAL-M1(Rgs5Acta2)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	VGLL3 HRCT1 HEY2 HRC	7.00e-05	182	54	4	da61e7cb2537c567968d8bd8baf537ecdff0ab18
ToppCell	Cerebellum-Endothelial-MURAL\|Cerebellum / BrainAtlas - Mouse McCarroll V32	VGLL3 HRCT1 HEY2 HRC	7.00e-05	182	54	4	b2f03f61aebb5920595fed8b9d6799a09353419b
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA6 HEY2 AUTS2 HRC	7.15e-05	183	54	4	4060d979948e1dd7507977629a7fbdfa4ca65bb6
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	NKD1 POU4F2 MTCL1 MN1	7.15e-05	183	54	4	a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCell	HSPCs-LMPPs\|HSPCs / Lineage and Cell class	HOXA9 SELENOP TSC22D1 PLK2	7.15e-05	183	54	4	f7392645d38da7285e797aa0e4625751af83ebd7
ToppCell	PND01-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GATA6 HEY2 AUTS2 HRC	7.15e-05	183	54	4	0d44a978221cf3f733704bf11863502805fba733
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	POU4F2 DLX2 CCER2 CREB5	7.30e-05	184	54	4	7aa245b73e10fd73d292e822de6b72920aa12355
ToppCell	droplet-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 GATA6 HEY2 FOXC2	7.45e-05	185	54	4	eeb6f55a6f79adf80247baa2c4b0df44553557ad
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ONECUT2 GATA6 MAFB PBXIP1	7.45e-05	185	54	4	4e40d3103ebf4a7066b7ce300b6ef700ba0e2863
ToppCell	systemic_lupus_erythematosus-managed-Hematopoietic-progenitor_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HOXA9 SELENOP TSC22D1 CCER2	7.45e-05	185	54	4	2c07991e0907ded67e21ab2e66be21695842ed01
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSC22D1 GATA6 HEY2 FOXC2	7.61e-05	186	54	4	9c7924875f70420720149287c500b4dfa8d24673
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	CPEB4 NUFIP2 MAFB CREB5	7.61e-05	186	54	4	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HOXA9 ONECUT2 SKIDA1 PRDM13	7.61e-05	186	54	4	bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1\|TCGA-Pancreas / Sample_Type by Project: Shred V9	USP34 GTF2A1 NKD1 LRCH1	7.61e-05	186	54	4	03db813598b67b1e08f759758a1c2023396921fa
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 GATA6 HEY2 FOXC2	7.61e-05	186	54	4	5302399825f213d105ac70b91366a4513b732838
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 PLK2 HRCT1 FOXF2	7.77e-05	187	54	4	3e25c15fa29f8c738044914e8b3420d5713f18d9
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HEY2 HRC MAFB FOXC2	7.77e-05	187	54	4	d52f7bc0afcdc366b20d199ab33c4ec60ed22a68
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSC22D1 GATA6 HEY2 FOXC2	7.77e-05	187	54	4	12129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 PLK2 HRCT1 FOXF2	7.77e-05	187	54	4	965584ee44669a72866a20ddf7f657bc5a7f7a8b
ToppCell	facs-Brain_Non-Myeloid-Striatum_-18m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 PLK2 HRCT1 FOXF2	7.77e-05	187	54	4	a7ef179e6561e17cafae10e1843bf82ac3ae0c89
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSC22D1 GATA6 HEY2 FOXC2	7.77e-05	187	54	4	83930ef55191eff9006113feaeabb3c2fa21fd05
ToppCell	COPD-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	HEY2 HRC CBL FOXC2	7.93e-05	188	54	4	9ffef4b01d0ddd6913c9ed6be79aeaaabd5e41ed
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Endothelial-endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOP TSC22D1 PLK2 FOXF2	7.93e-05	188	54	4	4dc89c7843ebd078e3414e835c56f11fa27f0c5f
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Endothelial-Endothelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOP TSC22D1 PLK2 FOXF2	7.93e-05	188	54	4	d577b3c2a844e3062c7ca9e9ebc1722d0ac95caa
ToppCell	facs-Brain_Non-Myeloid-Striatum-3m-Endothelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOP TSC22D1 PLK2 FOXF2	7.93e-05	188	54	4	1e788b60dd643bf220d8dfafa82d85fd083cbc71
ToppCell	droplet-Lung-nan-18m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSC22D1 GATA6 HEY2 FOXC2	7.93e-05	188	54	4	405efea75233ecf70f7d19b630230798d817b7f2
ToppCell	P03-Mesenchymal-myocytic_cell-vascular_associated_smooth_muscle_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HEY2 HRC CREB5 FOXC2	8.10e-05	189	54	4	b5439ef221106f6d54434f268485e9bb17b39102
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SELENOP VGLL3 AUTS2 CREB5	8.26e-05	190	54	4	7986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HRCT1 HEY2 HRC FOXC2	8.26e-05	190	54	4	1803b1e7c36285f9eaabc3c6e9a9752c5908db3d
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Stroma____kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NKD1 HEY2 HRC FOXC2	8.43e-05	191	54	4	8597a8af294f24496c317d995f07eb5dcc25c13c
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HEY2 HRC MAFB FOXC2	8.43e-05	191	54	4	239c1e68eb1cbe3e137a99fbd6eeb8d64c919ffd
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELENOP GATA6 MN1 CREB5	8.60e-05	192	54	4	0e7e55505bd5454d7cf952a63fdcb46ec76f1973
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEY2 HRC MN1 FOXC2	8.78e-05	193	54	4	18e11d515147accef9aee26e934b358b445e18e2
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HEY2 POU4F2 DLX2 CREB5	8.78e-05	193	54	4	4f4f430d7e1b65e19ca829f55ca93edeb6c1c85d
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SELENOP GATA6 MN1 CREB5	8.78e-05	193	54	4	025836c5c5a711e477c326559e618e47cae42d11
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEY2 HRC MN1 FOXC2	8.78e-05	193	54	4	7766f495f2f945802ef9a5b994cd00bb64d0dfe3
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn-22\|World / Primary Cells by Cluster	TSC22D1 AUTS2 CCER2 MN1	8.78e-05	193	54	4	3b927d4b8ecb21a408424ef91a23746c21741f49
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HEY2 HRC MN1 FOXC2	8.78e-05	193	54	4	ce3e8cf30b7b4d5c7a8f3d64c21d81d2c3cab5c1
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	GSX2 DLX2 PBXIP1 CREB5	8.95e-05	194	54	4	7c6c0376603e5fcb64814fd6204d153629c2fbf5
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HOXA9 ONECUT2 POU4F1 DLX2	8.95e-05	194	54	4	4e93bd903cddfd0c8f220b6a35b449895de4119b
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGLL3 HEY2 HRC FOXC2	8.95e-05	194	54	4	bf34737ae2dc218f890fbb9201c308b324415749
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGLL3 HEY2 HRC FOXC2	8.95e-05	194	54	4	b35e33439b6d3b5d69147e617224d2c8fd056223
ToppCell	facs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGLL3 HEY2 HRC FOXC2	8.95e-05	194	54	4	4ebed7a6731b88c8359860072cbeba355a7e90ac
ToppCell	(3)_Chondrocytes-(30)_Chondro\|(3)_Chondrocytes / Cell class and subclass of bone marrow stroma cells in homeostatis	AUTS2 SHOX2 MAFB PRR7	9.13e-05	195	54	4	f5597d3ed37770c6fa2b339f98a80ac7ecd4f9ff
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELENOP VGLL3 NKD1 FOXF2	9.13e-05	195	54	4	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELENOP VGLL3 NKD1 FOXF2	9.13e-05	195	54	4	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VGLL3 POU4F2 DLX2 CREB5	9.32e-05	196	54	4	9afd0a7135028a446f06bb68f334e79b8f171b45
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HEY2 HRC FOXF2 FOXC2	9.32e-05	196	54	4	9a420a4eb46cb554bec641726fea5398ff60f630
ToppCell	Pericytes\|World / shred by cell class for parenchyma	NKD1 HEY2 HRC FOXC2	9.32e-05	196	54	4	8e7ecbe77d312a7fc6aadd8fd52c13dd1834cc7e
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HEY2 HRC FOXF2 FOXC2	9.32e-05	196	54	4	cb5860f580b477bfa52b22cdc21b808e1371e6e0
ToppCell	367C-Fibroblasts-Fibroblast-K_(Pericytes)\|367C / Donor, Lineage, Cell class and subclass (all cells)	NKD1 HEY2 HRC FOXC2	9.32e-05	196	54	4	c390ef0adff35111989a30dff86b7c5db1a89873
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-Newborn\|World / Primary Cells by Cluster	TSC22D1 AUTS2 CCER2 MN1	9.32e-05	196	54	4	9401bd84798f0ea3e986e94135a9e1dc5643330f
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SELENOP VGLL3 NKD1 FOXF2	9.32e-05	196	54	4	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	367C-Fibroblasts-Fibroblast-K_(Pericytes)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	NKD1 HEY2 HRC FOXC2	9.32e-05	196	54	4	2f76f050083483f0880639e6c34ff349caac3503
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_OPC-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ONECUT2 TSC22D1 CCER2 CREB5	9.50e-05	197	54	4	d9a5b6171867de21d4ef12aa5a802fb4de9e0c00
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TSC22D1 HEY2 HRC FOXC2	9.50e-05	197	54	4	cc494a656db868bb489238a5becc31bc8518f3cc
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HEY2 HRC FOXF2 FOXC2	9.50e-05	197	54	4	12370ee857fddf1cf26196b23c21b68dcea48eb3
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-midbrain/hindbrain_cells\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	ONECUT2 POU4F1 POU4F2 ONECUT1	9.50e-05	197	54	4	c7078f6fcf27319ba8c5ebe700bcae7f1e7e39c1
ToppCell	PND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TSC22D1 HRCT1 HEY2 HRC	9.50e-05	197	54	4	1a6b2ca94a4634c24cd95481576c955b20000a5f
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSC22D1 NKD1 AUTS2 FOXC2	9.50e-05	197	54	4	4b6c0e028b9669c102df8e9dc63e284f8d5fd9ee
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TSC22D1 NKD1 AUTS2 FOXC2	9.50e-05	197	54	4	ece0c17eb68f394b20e588c0b0626d3987a4dbbb
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	VGLL3 GATA6 HRC FOXF2	9.50e-05	197	54	4	2872a78b1be61aa1d50bc9a49294a21e922dc033
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon\|organoid_Velasco_nature / Sample Type, Dataset, Time_group, and Cell type.	SELENOP GSX2 DLX2 PBXIP1	9.69e-05	198	54	4	a6f65bb0845d8f64f5c7edb00cee3ca5adb1a373
ToppCell	Transplant_Alveoli_and_parenchyma-Mesenchymal-Smooth_muscle\|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X	TSC22D1 HEY2 HRC FOXC2	9.69e-05	198	54	4	89986c7756541df364df516329d10775ba0e78a4
ToppCell	distal-Hematologic-IGSF21+_Dendritic-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	SELENOP MAFB ONECUT1 CREB5	9.69e-05	198	54	4	323b4e6c31e18227546bb30566c1d872fda45e36
ToppCell	distal-Endothelial-Artery-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TSC22D1 PLK2 HRCT1 GATA6	9.69e-05	198	54	4	f284f59f4ebe55ee132eddfaa2f5d9ecb059654f
ToppCell	10x3'2.3-week_14-16-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	SELENOP HEY2 SHOX2 FOXC2	9.69e-05	198	54	4	9d61483b0decac2fe90045b3474843360b2c49b3
ToppCell	5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VGLL3 HEY2 DLX2 CREB5	9.69e-05	198	54	4	52ddc1f1ed4ac4c3bac794c90b8feb03e3c221c4
ToppCell	cellseq-Mesenchymal-Myocytic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NKD1 HRC FOXF2 FOXC2	9.88e-05	199	54	4	20e62a7029fa0d214244cdf2a481fc5d78290438
Drug	Diphenhydramine hydrochloride [147-24-0]; Down 200; 13.8uM; MCF7; HT_HG-U133A	ONECUT2 GTF2A1 MAFB CACNA1I CBL LRCH1 NLK	3.32e-07	191	54	7	6020_DN
Drug	Hydrocortisone base [50-23-7]; Up 200; 11uM; MCF7; HT_HG-U133A	HOXA9 ZCCHC14 FAM120C FBXO41 MAFB POU4F1	6.51e-06	194	54	6	3284_UP
Drug	0317956-0000 [391210-11-0]; Up 200; 10uM; PC3; HT_HG-U133A	ONECUT2 GTF2A1 SHOX2 CACNA1I DLX2 LRCH1	6.90e-06	196	54	6	4331_UP
Drug	F0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A	ONECUT2 GTF2A1 HEY2 CACNA1I DLX2 PBXIP1	6.90e-06	196	54	6	6396_DN
Drug	Tenoxicam [59804-37-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A	HOXA9 ONECUT2 FBXO41 SHOX2 CBL PBXIP1	6.90e-06	196	54	6	4182_DN
Drug	Yohimbine hydrochloride [65-19-0]; Up 200; 10.2uM; MCF7; HT_HG-U133A	ZCCHC14 FBXO41 MAFB CACNA1I POU4F2 DLX2	7.32e-06	198	54	6	2755_UP
Drug	Thioperamide maleate [106243-16-7]; Up 200; 9.8uM; MCF7; HT_HG-U133A	FBXO41 HEY2 SHOX2 CACNA1I DLX2 ONECUT1	7.75e-06	200	54	6	5270_UP
Drug	Withaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A	ONECUT2 FAM120C MAFB DLX2 PBXIP1	7.88e-05	186	54	5	3902_DN
Drug	Lithocholic acid [434-13-9]; Up 200; 10.6uM; HL60; HT_HG-U133A	HOXA9 USP34 GATA6 MAFB PBXIP1	8.08e-05	187	54	5	2571_UP
Drug	Lovastatin [75330-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A	USP34 AUTS2 CACNA1I DLX2 CBL	8.29e-05	188	54	5	2854_UP
Drug	Phenacetin [62-44-2]; Up 200; 22.4uM; MCF7; HT_HG-U133A	USP34 ONECUT2 CACNA1I DLX2 CBL	8.50e-05	189	54	5	2832_UP
Drug	carbamazepine; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	USP34 ONECUT2 SHOX2 MAFB DLX2	8.72e-05	190	54	5	952_UP
Drug	Haloperidol [52-86-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A	ZCCHC14 FBXO41 HEY2 CACNA1I CBL	9.38e-05	193	54	5	5273_UP
Drug	Chlorpheniramine maleate [113-92-8]; Up 200; 10.2uM; PC3; HT_HG-U133A	GTF2A1 FBXO41 SHOX2 CACNA1I CREB5	9.38e-05	193	54	5	2055_UP
Drug	Furazolidone [67-45-8]; Down 200; 17.8uM; MCF7; HT_HG-U133A	USP34 AUTS2 SHOX2 CACNA1I PBXIP1	9.61e-05	194	54	5	4178_DN
Drug	Cinchonine [118-10-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A	ONECUT2 FBXO41 SHOX2 DLX2 PBXIP1	9.61e-05	194	54	5	2789_UP
Drug	Karakoline [39089-30-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A	USP34 ONECUT2 AUTS2 CACNA1I POU4F1	9.85e-05	195	54	5	6059_DN
Drug	Chicago sky blue 6B [2610-05-1]; Up 200; 4uM; MCF7; HT_HG-U133A	ONECUT2 GTF2A1 HEY2 CACNA1I CBL	9.85e-05	195	54	5	3266_UP
Drug	Betulinic acid [472-15-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A	FBXO41 SHOX2 POU4F2 ONECUT1 PBXIP1	9.85e-05	195	54	5	4181_DN
Drug	Capsaicin [404-86-4]; Up 200; 13uM; MCF7; HT_HG-U133A	ZCCHC14 FBXO41 MN1 PBXIP1 CREB5	9.85e-05	195	54	5	5673_UP
Drug	Ethotoin [86-35-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A	USP34 GTF2A1 CACNA1I CBL LRCH1	9.85e-05	195	54	5	6052_DN
Drug	Clofazimine [2030-63-9]; Up 200; 8.4uM; MCF7; HT_HG-U133A	ZCCHC14 FBXO41 SHOX2 CACNA1I ONECUT1	1.01e-04	196	54	5	5277_UP
Drug	Acacetin [480-44-4]; Up 200; 14uM; PC3; HT_HG-U133A	ONECUT2 HRG DLX2 LRCH1 FOXF2	1.01e-04	196	54	5	4324_UP
Drug	Dihydroergotoxine mesylate [8067-24-1]; Up 200; 6.4uM; MCF7; HT_HG-U133A	ONECUT2 FAM120C SHOX2 MAFB CACNA1I	1.01e-04	196	54	5	2793_UP
Drug	Tetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; PC3; HT_HG-U133A	ZCCHC14 GTF2A1 VGLL3 HEY2 SHOX2	1.01e-04	196	54	5	5757_UP
Drug	Crotamiton [483-63-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A	HOXA9 CACNA1I ONECUT1 FOXF2 FOXC2	1.01e-04	196	54	5	5689_UP
Drug	nordihydroguaiaretic acid; Up 200; 1uM; MCF7; HT_HG-U133A_EA	ZCCHC14 ONECUT2 GTF2A1 AUTS2 MAFB	1.03e-04	197	54	5	1003_UP
Drug	Alfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; MCF7; HT_HG-U133A	FBXO41 HEY2 DLX2 LRCH1 FOXF2	1.03e-04	197	54	5	5242_UP
Drug	Hexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; MCF7; HT_HG-U133A	ZCCHC14 USP34 ONECUT2 VGLL3 LRCH1	1.03e-04	197	54	5	3447_UP
Drug	Mevalonic-D, L acid lactone [674-26-0]; Up 200; 30.8uM; HL60; HT_HG-U133A	ONECUT2 POU4F1 MN1 PBXIP1 CREB5	1.03e-04	197	54	5	2718_UP
Drug	Hexylcaine hydrochloride [532-76-3]; Up 200; 13.4uM; PC3; HT_HG-U133A	VGLL3 SHOX2 DLX2 PRR7 FOXF2	1.03e-04	197	54	5	5768_UP
Drug	Moroxidine hydrochloride [3160-91-6]; Up 200; 19.2uM; PC3; HT_HG-U133A	ZCCHC14 GTF2A1 HRG POU4F1 LRCH1	1.03e-04	197	54	5	6705_UP
Drug	Hecogenin [467-55-0]; Up 200; 9.2uM; MCF7; HT_HG-U133A	HOXA9 ZCCHC14 GTF2A1 SHOX2 LRCH1	1.03e-04	197	54	5	3457_UP
Drug	Betonicine [515-25-3]; Up 200; 25.2uM; PC3; HT_HG-U133A	ONECUT2 GTF2A1 HRG SHOX2 LRCH1	1.06e-04	198	54	5	4301_UP
Drug	Thyroxine (L) [51-48-9]; Down 200; 5.2uM; MCF7; HT_HG-U133A	HEY2 AUTS2 CBL ONECUT1 PBXIP1	1.06e-04	198	54	5	4150_DN
Drug	Bromopride [4093-35-0]; Down 200; 11.6uM; MCF7; HT_HG-U133A	ONECUT2 SHOX2 CACNA1I POU4F1 CBL	1.06e-04	198	54	5	6037_DN
Drug	Oxamniquine [21738-42-1]; Down 200; 14.4uM; PC3; HT_HG-U133A	ONECUT2 VGLL3 MN1 CREB5 PRR7	1.06e-04	198	54	5	4006_DN
Drug	Metyrapone [54-36-4]; Up 200; 17.6uM; MCF7; HT_HG-U133A	ZCCHC14 VGLL3 HEY2 SHOX2 CBL	1.06e-04	198	54	5	6447_UP
Drug	Solasodine [126-17-0]; Up 200; 9.6uM; HL60; HT_HG-U133A	FBXO41 SHOX2 CACNA1I PBXIP1 FOXF2	1.06e-04	198	54	5	2170_UP
Drug	prochlorperazine dimaleate salt; Down 200; 10uM; MCF7; HT_HG-U133A	USP34 ONECUT2 FBXO41 LRCH1 NLK	1.08e-04	199	54	5	5575_DN
Drug	Tubocurarine chloride pentahydrate (+) [6989-98-6]; Up 200; 5.2uM; MCF7; HT_HG-U133A	FBXO41 HEY2 SHOX2 CACNA1I POU4F2	1.08e-04	199	54	5	5449_UP
Drug	LY 294002; Up 200; 10uM; HL60; HT_HG-U133A	GTF2A1 HRG CACNA1I ONECUT1 PBXIP1	1.08e-04	199	54	5	6186_UP
Drug	Tinidazole [19387-91-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A	USP34 SHOX2 MAFB LRCH1 PBXIP1	1.08e-04	199	54	5	3430_DN
Drug	Aspartic acid, N-acetyl (R,S) [997-55-7]; Up 200; 22.8uM; MCF7; HT_HG-U133A	GTF2A1 MAFB POU4F2 CBL PBXIP1	1.08e-04	199	54	5	3265_UP
Drug	Delcorine; Down 200; 8.4uM; MCF7; HT_HG-U133A	ZCCHC14 ONECUT2 SHOX2 CACNA1I POU4F1	1.08e-04	199	54	5	6033_DN
Drug	AC1L1FQE	PLK2 SHOX2 NONO	1.46e-04	43	54	3	CID000003349
Disease	AUTISM, SUSCEPTIBILITY TO, 15	AUTS2 NONO	8.80e-05	8	53	2	C2677504
Disease	monocyte count	HOXA9 SELENOP PLK2 TMEM121B NUFIP2 MAFB CBL ONECUT1 MN1 CREB5	1.04e-04	1320	53	10	EFO_0005091
Disease	Acute Cerebrovascular Accidents	ZCCHC14 LRCH1 FOXF2	1.27e-04	54	53	3	C0751956
Disease	Cerebrovascular accident	ZCCHC14 LRCH1 FOXF2	1.92e-04	62	53	3	C0038454
Disease	Leukemia, Myelocytic, Acute	HOXA9 POU4F1 CBL MN1	2.67e-04	173	53	4	C0023467
Disease	lysophosphatidylcholine 15:0 measurement	FBXO41 POU4F2	2.84e-04	14	53	2	EFO_0020941
Disease	semaphorin-3A measurement	HRG NLK	3.27e-04	15	53	2	EFO_0008278
Disease	electrocardiography	NUFIP2 GATA6 HEY2 HRG SHOX2 LRCH1	3.66e-04	530	53	6	EFO_0004327
Disease	Tetralogy of Fallot	GATA6 FOXC2	3.74e-04	16	53	2	C0039685
Disease	breast carcinoma	PLK2 VGLL3 NKD1 SKIDA1 MAFB MTCL1 MN1 CREB5	4.39e-04	1019	53	8	EFO_0000305
Disease	mosquito bite reaction size measurement	USP34 CPEB4 AUTS2 LRCH1	5.76e-04	212	53	4	EFO_0008378
Disease	Congenital diaphragmatic hernia	GATA6 FOXC2	6.50e-04	21	53	2	C0235833
Disease	partial thromboplastin time	SELENOP HRG	8.52e-04	24	53	2	EFO_0004310
Disease	congenital diaphragmatic hernia (biomarker_via_orthology)	GATA6 CBL	8.52e-04	24	53	2	DOID:3827 (biomarker_via_orthology)
Disease	blood strontium measurement	PLK2 MTCL1	1.08e-03	27	53	2	EFO_0021531
Disease	hearing threshold measurement	AUTS2 MTCL1	1.16e-03	28	53	2	EFO_0007618
Disease	FEV/FEC ratio	USP34 CPEB4 SKIDA1 GATA6 GSX2 MAFB MTCL1 MN1	1.47e-03	1228	53	8	EFO_0004713
Disease	Acute Myeloid Leukemia, M1	HOXA9 POU4F1 MN1	1.49e-03	125	53	3	C0026998
Disease	Acute Myeloid Leukemia (AML-M2)	HOXA9 POU4F1 MN1	1.49e-03	125	53	3	C1879321
Disease	multiple myeloma (is_marker_for)	CBL NONO	1.92e-03	36	53	2	DOID:9538 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PHHHHHHHPGLRAPG	CHD8	2501	Q9HCK8
HHHGVPHQRGESHHP	CATSPER1	46	Q8NEC5
HPTQTPQPHHHHHHH	DLX2	301	Q07687
GQPVQRHEHHHHHEH	NKD1	446	Q969G9
PQHQHHHHHHHLSVP	RBM33	631	Q96EV2
KLQPPGQHHRHHHLH	MTCL1	16	Q9Y4B5
GQHHRHHHLHPVAER	MTCL1	21	Q9Y4B5
HHHMHSHPHQHQTLP	CREB5	271	Q02930
HPHHHSHSHLHAHPA	CREB5	311	Q02930
HHHPLHPHHWAAAFH	HEY2	176	Q9UBP5
HHHHHHHHQALEPGD	POU4F1	101	Q01851
PRKHHQHHHQQQHHQ	NONO	16	Q15233
SHEQHPHGHHPHAHH	HRG	356	P04196
PHAHHPHEHDTHRQH	HRG	366	P04196
PHEHDTHRQHPHGHH	HRG	371	P04196
THRQHPHGHHPHGHH	HRG	376	P04196
AHDELGPHAHPHHHH	MAFB	151	Q9Y5Q3
GPHAHPHHHHHHQAS	MAFB	156	Q9Y5Q3
HLGIFHHHRHPGHVS	HRCT1	66	Q6UXD1
HHHRHPGHVSHVPNV	HRCT1	71	Q6UXD1
HVPNVGLHHHHHPRH	HRCT1	81	Q6UXD1
GLHHHHHPRHTPHHL	HRCT1	86	Q6UXD1
RVNHAHHHHHPPQHH	GSX2	121	Q9BZM3
HHHHPHHHQRLAGNV	ONECUT1	131	Q9UBC0
NAVPAAVYHHHHHHP	HOXA9	76	P31269
AVYHHHHHHPYVHPQ	HOXA9	81	P31269
PHHHHHHHHQRLSGN	ONECUT2	176	O95948
HHHHHHHHPLSVDPR	AUTS2	1126	Q8WXX7
SVATLHPLHHPHHHH	LRCH1	16	Q9Y2L9
GHHHQHHGHHHPQAP	FOXC2	386	Q99958
QHGGYHPHQHHPHSH	FOXJ2	371	Q9P0K8
HHHPQHHLHPGSAAA	NLK	46	Q9UBE8
SMAGHHHHHPHAHHP	OTX1	271	P32242
HSHPHVHVHPLLHHG	PRR7	91	Q8TB68
ARPLNGTYHHHHHHH	GATA6	316	Q92908
GERREDLPHHHHHHH	CCER2	206	I3L3R5
DLPHHHHHHHQPEAE	CCER2	211	I3L3R5
PRLPAVHHHHHHHHA	C21orf58	286	P58505
VHHHHHHHHAVWPPG	C21orf58	291	P58505
PLHTPHAHHIHHGPH	CACNA1I	1031	Q9P0X4
HAHHIHHGPHLAHRH	CACNA1I	1036	Q9P0X4
PIRHHHPAHHFHHHG	FAM120C	81	Q9NX05
AAPHLLHHHHHHAPL	FBXO41	101	Q8TF61
LHHHHHHAPLAHFPG	FBXO41	106	Q8TF61
DAFQPHHHHHHHLSP	CBL	31	P22681
QHHPHHPHFQHHHSQ	CPEB4	231	Q17RY0
HHAHHHHHPKCLLAG	PRDM13	356	Q9H4Q3
QPHHGHPGSHHPHQH	MN1	96	Q10571
HHHHHHHVPHMSPNP	FOXF2	266	Q12947
HHHAHAAHHPPFAEL	SYT3	131	Q9BQG1
HNHHLHHHHAAPPLH	TMEM121B	261	Q9BXQ6
HHHHHHHQPHQALEG	POU4F2	176	Q12837
HHHHHHRAQPPQQSH	SKIDA1	346	Q1XH10
SGTLHHPHHHHSVPH	SENP1	286	Q9P0U3
HPHHHHSVPHQPDNL	SENP1	291	Q9P0U3
HHHLHPHLAAHAPYM	SHOX2	261	O60902
VAHAHPHLHPHLAAH	SHOX	221	O15266
GSFHPHHLSHHHCHH	SIAH3	61	Q8IW03
LRHHAHPHHLHHQEA	SIAH3	81	Q8IW03
HPHHLHHQEAGLHAN	SIAH3	86	Q8IW03
INGNAHPHHLHHHHQ	TSC22D1	211	Q15714
IHHGHHLQHGHHHPS	TSC22D1	226	Q15714
HHHHGPSHRHQGHEE	HRC	231	P23327
AVSGEHHHHVPDHRH	HRC	331	P23327
HHHHVPDHRHQGHRD	HRC	336	P23327
PSPHYHHEHHHNHGH	SELENOP	201	P49908
PGLHHHHKHKGQHRQ	SELENOP	241	P49908
PQQQQHHHHHHHQQA	GTF2A1	76	P52655
GQPQPQHHHSHHHPH	NUFIP2	6	Q7Z417
HHPQQQQQQPHHHHH	NUFIP2	21	Q7Z417
HHHHHHQQPHQYLQH	NUFIP2	46	Q7Z417
GPREGHSHSHHHHHR	PBXIP1	716	Q96AQ6
PHRMHPNYGHGHHIH	RNF111	776	Q6ZNA4
IPASNPNHHHHHHHQ	ZCCHC14	756	Q8WYQ9
PHHHHHHSHSGPEIS	PLK2	56	Q9NYY3
CRQFIGPQHHHHHHH	USP34	741	Q70CQ2
RHHHHHHHPPAGSAL	VGLL3	241	A8MV65