Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainDUF4414

HUWE1 REV1

2.05e-052852IPR025527
DomainDUF4414

HUWE1 REV1

2.05e-052852PF14377
DomainCysteine_rich_secretory

CRISP2 CRISP1

6.12e-053852IPR013871
DomainCrisp

CRISP2 CRISP1

6.12e-053852PF08562
DomainCAF1C_H4-bd

RBBP4 RBBP7

6.12e-053852PF12265
DomainHistone-bd_RBBP4_N

RBBP4 RBBP7

6.12e-053852IPR022052
DomainARM-type_fold

DOCK3 USP34 KIFAP3 IPO8 MTOR HUWE1 CTNND2 HTT

1.55e-04339858IPR016024
DomainSHKT

CRISP2 CRISP1

2.03e-045852PS51670
DomainShKT_dom

CRISP2 CRISP1

2.03e-045852IPR003582
DomainPTPc

PTPN4 PTPRC PTPRF

5.83e-0436853SM00194
DomainTYR_PHOSPHATASE_PTP

PTPN4 PTPRC PTPRF

7.39e-0439853PS50055
DomainPTPase_domain

PTPN4 PTPRC PTPRF

8.56e-0441853IPR000242
DomainY_phosphatase

PTPN4 PTPRC PTPRF

8.56e-0441853PF00102
DomainAllrgn_V5/Tpx1_CS

CRISP2 CRISP1

9.00e-0410852IPR018244
DomainCRISP_1

CRISP2 CRISP1

1.10e-0311852PS01009
DomainCRISP_2

CRISP2 CRISP1

1.10e-0311852PS01010
DomainWW

WWP2 APBB2 PRPF40A

1.28e-0347853PF00397
DomainWW

WWP2 APBB2 PRPF40A

1.36e-0348853SM00456
DomainARM-like

KIFAP3 IPO8 MTOR HUWE1 CTNND2 HTT

1.45e-03270856IPR011989
DomainWW_DOMAIN_2

WWP2 APBB2 PRPF40A

1.62e-0351853PS50020
DomainWW_DOMAIN_1

WWP2 APBB2 PRPF40A

1.62e-0351853PS01159
DomainWW_dom

WWP2 APBB2 PRPF40A

1.71e-0352853IPR001202
DomainATPase_dyneun-rel_AAA

MDN1 DNAH2

1.80e-0314852IPR011704
DomainAAA_5

MDN1 DNAH2

1.80e-0314852PF07728
Domain-

PTPN4 ARHGAP24 PSD FGD2 PLCL2 APBB2 BCR

2.03e-033918572.30.29.30
Domain-

CRISP2 CRISP1

2.07e-03158523.40.33.10
DomainCAP

CRISP2 CRISP1

2.07e-0315852PF00188
DomainCAP_domain

CRISP2 CRISP1

2.07e-0315852IPR014044
DomainSCP

CRISP2 CRISP1

2.07e-0315852SM00198
DomainAllrgn_V5/Tpx1

CRISP2 CRISP1

2.07e-0315852IPR001283
DomainPTPc_motif

PTPN4 PTPRC PTPRF

2.46e-0359853SM00404
DomainTyr_Pase_cat

PTPN4 PTPRC PTPRF

2.46e-0359853IPR003595
DomainUBA-like

UBAC1 NT5C2 HUWE1

3.10e-0364853IPR009060
DomainPH_dom-like

PTPN4 ARHGAP24 PSD FGD2 PLCL2 APBB2 BCR

3.27e-03426857IPR011993
Domain-

KIFAP3 IPO8 MTOR CTNND2 HTT

3.44e-032228551.25.10.10
DomainCH

DST SPEF2 SYNE2

4.50e-0373853PS50021
DomainTyr_Pase_AS

PTPN4 PTPRC PTPRF

4.50e-0373853IPR016130
DomainZnf_FYVE_PHD

ZFYVE9 FGD2 JADE2 SP110

4.55e-03147854IPR011011
DomainCH-domain

DST SPEF2 SYNE2

4.85e-0375853IPR001715
PathwayREACTOME_RHO_GTPASE_CYCLE

DOCK3 ARHGAP24 CCDC88A DST FGD2 WWP2 CFTR BCR GARRE1 CEP97

5.50e-054506810M27078
Pubmed

Functional proteomics mapping of a human signaling pathway.

MRTFB DST PTPRC ZFYVE9 PTPRF WWP2 UBAC1 PLCL2 HUWE1 PRPF40A

3.48e-06591911015231748
Pubmed

Scanning the human proteome for calmodulin-binding proteins.

DOCK3 DST SYNE2 NT5C2 HUWE1

4.51e-069291515840729
Pubmed

Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function.

MRTFB PTPRC WT1

4.86e-061391329114040
Pubmed

FAN1 modifies Huntington's disease progression by stabilizing the expanded HTT CAG repeat.

HTT FAN1

6.77e-06291230358836
Pubmed

Induction of Rb-associated protein (RbAp46) by Wilms' tumor suppressor WT1 mediates growth inhibition.

RBBP7 WT1

6.77e-0629129765217
Pubmed

Myelinosomes act as natural secretory organelles in Sertoli cells to prevent accumulation of aggregate-prone mutant Huntingtin and CFTR.

CFTR HTT

6.77e-06291227493027
Pubmed

Characterization of the gene encoding mouse retinoblastoma binding protein-7, a component of chromatin-remodeling complexes.

RBBP4 RBBP7

6.77e-06291212376095
Pubmed

Interpreting the molecular mechanisms of RBBP4/7 and their roles in human diseases (Review).

RBBP4 RBBP7

6.77e-06291238577935
Pubmed

SF3B3-regulated mTOR alternative splicing promotes colorectal cancer progression and metastasis.

SF3B3 MTOR

6.77e-06291238671459
Pubmed

Integrin CD11a cytoplasmic tail interacts with the CD45 membrane-proximal protein tyrosine phosphatase domain 1.

PTPRC ITGAL

6.77e-06291215946252
Pubmed

The δ2 glutamate receptor gates long-term depression by coordinating interactions between two AMPA receptor phosphorylation sites.

PTPN4 GRID2

6.77e-06291223431139
Pubmed

Distinct functional roles of the two intracellular phosphatase like domains of the receptor-linked protein tyrosine phosphatases LCA and LAR.

PTPRC PTPRF

6.77e-0629121695146
Pubmed

Divergent regulation of α-arrestin ARRDC3 function by ubiquitination.

WWP2 ARRDC3

6.77e-06291237223976
Pubmed

CTNNAL1 deficiency suppresses CFTR expression in HDM-induced asthma mouse model through ROCK1-CAL signaling pathway.

CTNNAL1 CFTR

6.77e-06291237715489
Pubmed

Interaction with polyglutamine-expanded huntingtin alters cellular distribution and RNA processing of huntingtin yeast two-hybrid protein A (HYPA).

PRPF40A HTT

6.77e-06291221566141
Pubmed

Effects of an ectodermal microceptor preparation on motor coordination in cerebellar mutant mice.

DST GRID2

6.77e-0629127886086
Pubmed

Overlapping functions of RBBP4 and RBBP7 in regulating cell proliferation and histone H3.3 deposition during mouse preimplantation development.

RBBP4 RBBP7

6.77e-06291234709113
Pubmed

High-Confidence Interactome for RNF41 Built on Multiple Orthogonal Assays.

CTNNAL1 MRTFB FAR1 CEP97

9.21e-065091429560723
Pubmed

Cloning and characterization of PTP-K1, a novel nonreceptor protein tyrosine phosphatase highly expressed in bone marrow.

PTPN4 PTPRC PTPRF

9.47e-06169138875997
Pubmed

Examining post-translational modification-mediated protein-protein interactions using a chemical proteomics approach.

RBBP4 JADE2 RBBP7

1.15e-051791323281010
Pubmed

Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures.

KIFAP3 WT1 BCR HTT

1.16e-055391436265442
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

POLR1F CCDC88A MDN1 DST RBBP7 MTOR WWP2 SYNE2 BCR GARRE1 PABIR2

1.57e-05861911136931259
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PTPN4 CTNNAL1 CCDC88A PTPRC ZFYVE9 PTPRF KLHL15 SYNE2 PLCL2 HUWE1 PABIR2 FAN1

1.88e-051049911227880917
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

PTPRF RBBP7 WWP2 ARRDC3 HUWE1 BCR PRPF40A

1.90e-0531391738270169
Pubmed

HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.

USP34 CCDC88A HSPA4L RBBP7 SSR1 HUWE1 FAR1 CEP97 KCTD17

1.93e-0557191937167062
Pubmed

Identification of two new members of the CSMD gene family.

CSMD1 CSMD3

2.03e-05391212906867
Pubmed

Spatial learning in a Z-maze by cerebellar mutant mice.

GRID2 C5

2.03e-0539128848495
Pubmed

Dual retinoblastoma-binding proteins with properties related to a negative regulator of ras in yeast.

RBBP4 RBBP7

2.03e-0539127503932
Pubmed

F-actin rearrangement is regulated by mTORC2/Akt/Girdin in mouse fertilized eggs.

CCDC88A MTOR

2.03e-05391227666957
Pubmed

Sensorimotor learning in three cerebellar mutant mice.

GRID2 C5

2.03e-0539128833100
Pubmed

The protein-tyrosine phosphatase PTPMEG interacts with glutamate receptor delta 2 and epsilon subunits.

PTPN4 GRID2

2.03e-05391210748123
Pubmed

Distribution of dopamine transporters in basal ganglia of cerebellar ataxic mice by [125I]RTI-121 quantitative autoradiography.

DST GRID2

2.03e-0539129460703
Pubmed

The role of retinoblastoma-associated proteins 46 and 48 in estrogen receptor alpha mediated gene expression.

RBBP4 RBBP7

2.03e-05391218577416
Pubmed

CRISPs Function to Boost Sperm Power Output and Motility.

CRISP2 CRISP1

2.03e-05391234422816
Pubmed

The cytoplasmic domain of TGFβR3 through its interaction with the scaffolding protein, GIPC, directs epicardial cell behavior.

TGFBR3 WT1

2.03e-05391221871877
Pubmed

Interaction of the nuclear matrix protein NAKAP with HypA and huntingtin: implications for nuclear toxicity in Huntington's disease pathogenesis.

PRPF40A HTT

2.03e-05391216391387
Pubmed

The human cysteine-rich secretory protein (CRISP) family. Primary structure and tissue distribution of CRISP-1, CRISP-2 and CRISP-3.

CRISP2 CRISP1

2.03e-0539128665901
Pubmed

Provide fluoxetine information vital to clinicians.

MTOR WT1

2.03e-0539128530339
Pubmed

Inhibition of ICAM-1/LFA-1 interactions prevents B-cell-dependent anti-CD45RB-induced transplantation tolerance.

PTPRC ITGAL

2.03e-05391218337659
Pubmed

Real-time quantitative PCR detection of WT1 and M-BCR-ABL expressions in chronic myeloid leukemia.

WT1 BCR

2.03e-05391226429162
Pubmed

Functional redundancy and compensation: Deletion of multiple murine Crisp genes reveals their essential role for male fertility.

CRISP2 CRISP1

2.03e-05391233037689
Pubmed

Indefinite survival of neonatal porcine islet xenografts by simultaneous targeting of LFA-1 and CD154 or CD45RB.

PTPRC ITGAL

2.03e-05391215677502
Pubmed

The MTA1 subunit of the nucleosome remodeling and deacetylase complex can recruit two copies of RBBP4/7.

RBBP4 RBBP7

2.03e-05391227144666
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

USP34 SF3B3 MDN1 DST IPO8 HSPA4L RBBP4 JADE2 RBBP7 MTOR SYNE2 HUWE1 FAR1 GARRE1

2.21e-051440911430833792
Pubmed

Analysis of phosphorylation-dependent protein-protein interactions of histone h3.

RBBP4 RBBP7 PRPF40A

2.23e-052191325330109
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

USP34 CCDC88A MRTFB SF3B3 RBBP4 RBBP7 HUWE1 BCR GARRE1

2.43e-0558891938580884
Pubmed

Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.

SF3B3 MDN1 HSPA4L RBBP4 RBBP7 WWP2

2.48e-0521991631353912
Pubmed

Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.

DOCK3 ARHGAP24 IPO8 FGD2 HSPA4L RBBP4 RBBP7 NT5C2 HUWE1 ECH1 BCR

2.77e-05916911132203420
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PTPN4 MRTFB KCND3 RBBP4 JADE2 WWP2 NT5C2 APBB2 PATL1 HUWE1 CSMD1 ECH1 BCR HTT

3.19e-051489911428611215
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

USP34 SF3B3 PSD RBBP4 RBBP7 RTL9 FAR1 CSMD1 BCR SP110 PRPF40A GARRE1

3.44e-051116911231753913
Pubmed

A directed protein interaction network for investigating intracellular signal transduction.

KIFAP3 UBR1 PTPN4 SF3B3 RBBP4 MTOR SYNE2 WT1 SSR1 CTNND2 SP110 PRPF40A

3.69e-051124911221900206
Pubmed

ARHGAP24 inhibits cell proliferation and cell cycle progression and induces apoptosis of lung cancer via a STAT6-WWP2-p27 axis.

ARHGAP24 WWP2

4.05e-05491231430374
Pubmed

PTEN Lipid Phosphatase Activity Suppresses Melanoma Formation by Opposing an AKT/mTOR/FRA1 Signaling Axis.

MTOR FOSL1

4.05e-05491238193852
Pubmed

Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease.

MTOR HTT

4.05e-05491225351248
Pubmed

Isolation of human NURF: a regulator of Engrailed gene expression.

RBBP4 RBBP7

4.05e-05491214609955
Pubmed

Histone binding protein RbAp48 interacts with a complex of CREB binding protein and phosphorylated CREB.

RBBP4 RBBP7

4.05e-05491210866654
Pubmed

Structural insights into the specific binding of huntingtin proline-rich region with the SH3 and WW domains.

PRPF40A HTT

4.05e-05491217161366
Pubmed

Identification of a genetic interaction between the tumor suppressor EAF2 and the retinoblastoma protein (Rb) signaling pathway in C. elegans and prostate cancer cells.

RBBP4 RBBP7

4.05e-05491224727455
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ARHGAP24 CCDC88A MDN1 DST CLIP2 MTOR SYNE2 NT5C2 HUWE1 CTNND2 BCR

4.36e-05963911128671696
Pubmed

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.

MRTFB DST JADE2 WWP2 CSMD1

4.66e-0514991525231870
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

USP34 PTPN4 CTNNAL1 IPO8 PTPRF HSPA4L RBBP7 MTOR HUWE1 FAR1 BCR

4.83e-05974911128675297
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

MDN1 IPO8 HSPA4L RBBP4 MTOR CFTR SSR1 HUWE1 FAR1

5.10e-0564791926618866
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

USP34 MDN1 DST RBBP4 RBBP7 MTOR SYNE2 HUWE1 PRPF40A

5.47e-0565391922586326
Pubmed

Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.

MRTFB SF3B3 RBBP4 RBBP7 SSR1 HUWE1 ECH1

6.16e-0537791725147182
Pubmed

Mac-1 (CD11b/CD18) and CD45 mediate the adhesion of hematopoietic progenitor cells to stromal cell elements via recognition of stromal heparan sulfate.

PTPRC ITGAL

6.74e-0559128043862
Pubmed

Mrg15 stimulates Ash1 H3K36 methyltransferase activity and facilitates Ash1 Trithorax group protein function in Drosophila.

RBBP4 RBBP7

6.74e-05591229158494
Pubmed

MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex.

RBBP4 RBBP7

6.74e-05591210471499
Pubmed

ARMC5 is part of an RPB1-specific ubiquitin ligase implicated in adrenal hyperplasia.

SF3B3 HSPA4L RBBP4 HUWE1 FAR1

7.79e-0516691535687106
Pubmed

Genome-wide association study of lung function decline in adults with and without asthma.

SYNE2 CTNND2 CSMD1

8.13e-053291322424883
Pubmed

The recombinant congenic strains--a novel genetic tool applied to the study of colon tumor development in the mouse.

PTPRC C5 ITGAL

9.78e-05349131686571
Pubmed

Nucleosomal DNA regulates the core-histone-binding subunit of the human Hat1 acetyltransferase.

RBBP4 RBBP7

1.01e-0469129427644
Pubmed

Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.

HTT FAN1

1.01e-04691232876667
Pubmed

CRL4(RBBP7) is required for efficient CENP-A deposition at centromeres.

RBBP4 RBBP7

1.01e-04691225795299
Pubmed

Ablation of PI3K blocks BCR-ABL leukemogenesis in mice, and a dual PI3K/mTOR inhibitor prevents expansion of human BCR-ABL+ leukemia cells.

MTOR BCR

1.01e-04691218704194
Pubmed

CRL4BRBBP7 targets HUWE1 for ubiquitination and proteasomal degradation.

RBBP7 HUWE1

1.01e-04691229738775
Pubmed

Functional and physical interaction between the histone methyl transferase Suv39H1 and histone deacetylases.

RBBP4 RBBP7

1.01e-04691211788710
Pubmed

BRCA1 interacts with components of the histone deacetylase complex.

RBBP4 RBBP7

1.01e-04691210220405
Pubmed

SUMO modification enhances p66-mediated transcriptional repression of the Mi-2/NuRD complex.

RBBP4 RBBP7

1.01e-04691216738318
Pubmed

The α-arrestin ARRDC3 mediates ALIX ubiquitination and G protein-coupled receptor lysosomal sorting.

WWP2 ARRDC3

1.01e-04691226490116
Pubmed

The structure of the core NuRD repression complex provides insights into its interaction with chromatin.

RBBP4 RBBP7

1.01e-04691227098840
Pubmed

Expression, purification and characterization of the human MTA2-RBBP7 complex.

RBBP4 RBBP7

1.01e-04691228179136
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

USP34 CCDC88A MRTFB DST HUWE1 FAR1 BCR

1.17e-0441891734709266
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

PTPN4 SF3B3 IPO8 PTPRF KLHL15 SSR1 FAR1 ECH1

1.33e-0457391828330616
Pubmed

Smad-dependent recruitment of a histone deacetylase/Sin3A complex modulates the bone morphogenetic protein-dependent transcriptional repressor activity of Nkx3.2.

RBBP4 RBBP7

1.41e-04791214612411
Pubmed

Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.

PTPRC PTPRF

1.41e-04791212376545
Pubmed

Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex.

RBBP4 RBBP7

1.41e-04791219686092
Pubmed

Identification and typing of members of the protein-tyrosine phosphatase gene family expressed in mouse brain.

PTPRC PTPRF

1.41e-0479121454056
Pubmed

Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice.

PTPRC WT1

1.41e-04791215342464
Pubmed

CDK2AP1/DOC-1 is a bona fide subunit of the Mi-2/NuRD complex.

RBBP4 RBBP7

1.41e-04791220523938
Pubmed

Expression of protein tyrosine phosphatase genes in the developing brain of mouse and rat.

PTPN4 PTPRF

1.41e-0479127804149
Pubmed

Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein.

RBBP4 RBBP7

1.41e-04791212435631
Pubmed

Strain distribution pattern for SSLP markers in the SWXJ recombinant inbred strain set: chromosomes 1 to 6.

PTPRC C5

1.41e-0479128747926
Pubmed

Transcription-coupled nucleotide excision repair is coordinated by ubiquitin and SUMO in response to ultraviolet irradiation.

SF3B3 RBBP4 RBBP7 FOSL1

1.53e-0410291431722399
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

DOCK3 MDN1 HUWE1 GARRE1

1.65e-041049149205841
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

POLR1F SF3B3 MDN1 HSPA4L RBBP4 RBBP7 WT1 PATL1 HUWE1 FAR1 ECH1 PRPF40A

1.66e-041318911230463901
Pubmed

Genetic composition of the recombinant congenic strains.

PTPRC C5 ITGAL

1.72e-04419138903730
Pubmed

ING tumor suppressor proteins are critical regulators of chromatin acetylation required for genome expression and perpetuation.

RBBP4 JADE2 RBBP7

1.85e-044291316387653
Pubmed

Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase.

PTPRC MTOR

1.88e-04891228636954
Pubmed

The zinc finger and C-terminal domains of MTA proteins are required for FOG-2-mediated transcriptional repression via the NuRD complex.

RBBP4 RBBP7

1.88e-04891218067919
Pubmed

Polycomb-like 2 associates with PRC2 and regulates transcriptional networks during mouse embryonic stem cell self-renewal and differentiation.

RBBP4 RBBP7

1.88e-04891220144788
InteractionCSNK2A2 interactions

PTPN4 PTPRC RBBP4 JADE2 RBBP7 NT5C2 PATL1 ARRDC3 HUWE1 BCR SP110 NKAPL PRPF40A HTT

2.62e-067188814int:CSNK2A2
InteractionTUBA1B interactions

ARHGAP24 PTPRF RBM45 KCND3 RBBP7 MTOR CFTR HUWE1 PRPF40A CEP97 HTT

1.08e-054988811int:TUBA1B
InteractionKPNB1 interactions

ARHGAP24 SF3B3 IPO8 RBM45 CFTR NT5C2 ARRDC3 HUWE1 SP110 HTT FAN1

2.45e-055448811int:KPNB1
InteractionRPA4 interactions

USP34 MDN1 DST IPO8 HSPA4L RBBP4 RBBP7 MTOR PRPF40A CEP97

2.76e-054528810int:RPA4
InteractionHSPA4 interactions

ARHGAP24 KCND3 HSPA4L RBBP4 RBBP7 MTOR APTX CFTR WT1 HUWE1 BCR HTT

3.22e-056678812int:HSPA4
Cytoband1q31.1

BRINP3 RGS21

1.39e-0499121q31.1
CytobandEnsembl 112 genes in cytogenetic band chr1q31

BRINP3 PTPRC RGS21

4.59e-0475913chr1q31
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRC PTPRF PTPRQ

4.21e-0521593813
GeneFamilyLysine methyltransferases|Myb/SANT domain containing|Polycomb repressive complex 2

RBBP4 RBBP7

1.56e-0465921347
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

RBBP4 RBBP7

3.71e-0495921306
GeneFamilyHistone deacetylases, class I|EMSY complex|NuRD complex|SIN3 histone deacetylase complex

RBBP4 RBBP7

6.77e-04125921243
GeneFamilyPHD finger proteins|NuRD complex

RBBP4 RBBP7

6.77e-04125921305
GeneFamilyFibronectin type III domain containing

PTPRC PTPRF PTPRQ CNTN2

1.84e-03160594555
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ARHGAP24 PSD FGD2 BCR

4.57e-03206594682
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

ZFYVE9 FGD2

4.58e-033159281
CoexpressionGSE22886_IGM_MEMORY_BCELL_VS_BLOOD_PLASMA_CELL_UP

HLA-DOB JADE2 WWP2 WT1 SP110 GARRE1 CNTN2

5.55e-06198907M4451
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

USP34 CTNNAL1 MRTFB DST SPEF2 SYNE2 GARRE1

1.82e-07200917dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellfacs-Marrow-B-cells-24m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXL13 PTPRF RTL9 GRID2 CTNND2 CSMD1

4.95e-071439166df16bf0324661cd9707df69cb39f4b5498d6d49
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|kidney / Disease (COVID-19 only), tissue and cell type

CATSPERD DNAH2 GRID2 CTNND2 CSMD1 CSMD3

5.59e-07146916c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCelldroplet-Lung-nan-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDN1 FGD2 CRISP1 HLA-DOB GPR149 CTNND2

1.10e-06164916a67dd181eba275c191f4d0cab13df30eaa3ad913
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CATSPERD DNAH2 GRID2 CTNND2 CSMD1 CSMD3

1.23e-061679163edb0570e583bb527165bcd8a4c25a042054043b
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAA25 MDN1 PSD FGD2 MTOR CTNND2

1.61e-06175916bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCellCOVID-19_Severe-CD4+_CTL|COVID-19_Severe / disease group, cell group and cell class

TGFBR3 PTPN4 GPR19 PTPRC SPEF2 SYNE2

1.72e-0617791634e9455790bae905dd91923792f4109d18b7686e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

CLIP2 CATSPERD ACOT11 PTPRQ GRID2 CSMD1

1.96e-06181916c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DST ZFYVE9 PTPRF PTPRQ APBB2 CTNND2

2.15e-0618491657c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DST ZFYVE9 PTPRF PTPRQ APBB2 CTNND2

2.15e-06184916d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPN4 CTNNAL1 MDN1 CLIP2 RBP2 BCR

2.22e-06185916bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCellCTRL-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

FCHSD2 ARHGAP24 FGD2 CLIP2 HLA-DOB SP110

2.52e-0618991614f3a8c0f4f057ad4e6839b4c3eeaf956d6dc92e
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBR3 DST KCND3 PTPRQ WT1 RAET1E

2.75e-06192916ef0aba777072429a6ab7dcfcc305673975946580
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CTNNAL1 MRTFB DST SPEF2 APBB2 CTNND2

2.92e-061949160b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_cell-B_mature|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FCHSD2 ARHGAP24 FGD2 CLIP2 HLA-DOB SP110

3.01e-061959163311a1bf4ed94820b45047d44fc14b14ac72e6fb
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

TGFBR3 PTPN4 PTPRC JADE2 SYNE2 ITGAL

3.01e-061959169990440bda7fac5d00ef80444fab07459be625e1
ToppCellhealthy_donor-Lymphocytic-T_cell-CD8+_Memory_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL BCR

3.10e-06196916af00c31612e4fe068e5fccae05368edba46bbd20
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TGFBR3 PTPN4 PTPRC JADE2 SYNE2 ITGAL

3.10e-06196916418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TGFBR3 PTPN4 PTPRC JADE2 SYNE2 ITGAL

3.10e-06196916581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TGFBR3 PTPN4 PTPRC JADE2 SYNE2 ITGAL

3.10e-061969166beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TGFBR3 PTPN4 PTPRC JADE2 SYNE2 ITGAL

3.10e-06196916c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TGFBR3 PTPN4 PTPRC JADE2 SYNE2 ITGAL

3.19e-06197916836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCellCV|World / Virus stimulation, Condition and Cluster

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL SP110

3.29e-061989166a28193af35abec5c029129930c2ca6febaafde2
ToppCellCD8+_Memory_T_cell-CV|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL SP110

3.29e-061989163d1749f5106f0912f4a74615863853949f52c73d
ToppCellBronchial_Biopsy|World / Tissue, Lineage and Cell class of Lung Cells from 10X

MRTFB DST PTPRF HSPA4L ACOT11 SYNE2

3.29e-06198916f5b7013045b61fc56894f80092f799770dde1c8f
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-Vein|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TGFBR3 CTNNAL1 DST SYNE2 BCR GARRE1

3.48e-062009167eb366b2c5394af7c77650bde6261e7dac67154e
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Gen_Cap|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CTNNAL1 MRTFB DST SPEF2 SYNE2 GARRE1

3.48e-06200916a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

TGFBR3 PTPN4 PTPRC SYNE2 HUWE1 ITGAL

3.48e-062009162281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellLPS_anti-TNF-Endothelial-Endothelial-Artery|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CTNNAL1 DST SYNE2 CSMD1 BCR GARRE1

3.48e-06200916b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

TGFBR3 PTPN4 PTPRC JADE2 SYNE2 ITGAL

3.48e-06200916f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CRISP2 MDN1 RBM45 CEP97 FAN1

9.17e-06137915ed81624b9167255ce88dcf6ad7f1636376ea0525
ToppCellPND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast|PND07-28-samps / Age Group, Lineage, Cell class and subclass

CRISP2 MDN1 RBM45 CEP97 FAN1

9.17e-0613791547859aa25f32367461c1ec75ed9060bee430c6b7
ToppCellfacs-Marrow-B-cells-24m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXL13 PTPRF GRID2 CTNND2 CSMD1

1.29e-051479159d7e965fe61bd7b31e09c4b2129a5a98c36f4811
ToppCellfacs-Marrow-B-cells-24m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXL13 PTPRF GRID2 CTNND2 CSMD1

1.29e-0514791538552953ff65a0fc20bee6ef57dc5885306ad18b
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells-Cycling_B_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC88A HLA-DOB JADE2 SYNE2 PTPRQ

1.72e-05156915203ef22eb76bd2b829b027c30af0557080f4006c
ToppCelldroplet-Lung-nan-3m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MDN1 FGD2 HLA-DOB GPR149 CTNND2

2.06e-051629158a488ecd25ef41468c3c7766eb936dbc2f7665a9
ToppCelldroplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBXL13 PTPRF FGD2 SPEF2 CTNND2

2.32e-051669151ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCelldroplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FBXL13 PTPRF FGD2 SPEF2 CTNND2

2.32e-051669154cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

FCHSD2 ARHGAP24 PTPRC PLCL2 SP110

2.45e-05168915a7159a35fe37f8c241cf8d391debe271e0698105
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_Lgr5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CRISP2 WT1 RAET1E

2.53e-0528913065da9144b7d8c79a583122288f1e7b5db86a794
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 ARHGAP24 PTPRC FGD2 SP110

2.60e-05170915a965e3ee6818790a4a6916824fde64333d9b11b7
ToppCellE16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CATSPERD HSPA4L SPEF2 DNAH2 CSMD1

2.67e-051719154f2a83d8091f1fd29542d2e5add57fd482e921b5
ToppCellfacs-Lung-EPCAM-24m-Myeloid-Myeloid_Dendritic_Type_1|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88A PTPRC FGD2 HLA-DOB CTNND2

2.75e-05172915cabe7b4131d72da87d3caacd8cced3a4f2cbef53
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

DST ZFYVE9 PTPRQ APBB2 CTNND2

2.90e-05174915548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXL13 PTPRF FGD2 CTNND2 BCR

3.07e-05176915d4075796c38b775fe721abb47426e662a0d415e3
ToppCellFetal_29-31_weeks-Immune-dendritic_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FCHSD2 CCDC88A PTPRC FGD2 ITGAL

3.15e-05177915c5e829bc4594761666d65cace5a9c5d19c16f187
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

FCHSD2 MDN1 DST CSMD3 BCR

3.15e-05177915e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC FGD2 HLA-DOB ITGAL SP110

3.24e-05178915ee674e379ee57e40eb2560ff5ed4c13d8db7ed9d
ToppCell356C-Lymphocytic-NK_cells-NK_cell_C|356C / Donor, Lineage, Cell class and subclass (all cells)

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL

3.24e-051789157203149864cc8d5ae25329fdbf15c6b73c3d3595
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC FGD2 HLA-DOB ITGAL SP110

3.24e-051789156c45bf197d6c1be0ef7d3a644c0062acf1e24e4d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Myeloid-macrophage|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC FGD2 HLA-DOB ITGAL SP110

3.24e-05178915cd85dcefe94ee742db64b63e105e13532321894a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBR3 DST PTPRQ WT1 RAET1E

3.32e-051799157394e77e665bf16d3733df91bb12907be460ab44
ToppCellCOVID-19-kidney-Bcells|kidney / Disease (COVID-19 only), tissue and cell type

FCHSD2 ARHGAP24 PTPRC FGD2 SP110

3.41e-051809155650fc7ebcdf5e0be9a217a58d36a8386d59fd1b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 ARHGAP24 PTPRC FGD2 SP110

3.41e-0518091565c069585737302a69b9a01476f4eb8b50cb2bfd
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBR3 DST PTPRQ WT1 RAET1E

3.50e-051819155bf7aa43f6e6ecce15c95928b91195544d6928c4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBR3 DST PTPRQ WT1 RAET1E

3.50e-051819158e751f5d7cd2d328ec0196d874e8a507e8c4e1a9
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCN11A CTNNAL1 RBP2 BCR KCTD17

3.60e-05182915d22ab50b135482915687c70e6dad29bfe2bb2c68
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBR3 KCND3 PTPRQ WT1 APBB2

3.69e-051839153c516fe5083f02bad1f464ed284010b4131a833c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBR3 KCND3 PTPRQ WT1 APBB2

3.69e-051839159c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFTR PTPRQ CSMD1 CSMD3 CNTN2

3.79e-051849152cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFTR PTPRQ CSMD1 CSMD3 CNTN2

3.79e-05184915ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFTR PTPRQ CSMD1 CSMD3 CNTN2

3.79e-051849152b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBR3 KCND3 PTPRQ WT1 APBB2

3.79e-051849157294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

DST PTPRF PTPRQ APBB2 CTNND2

3.89e-051859151c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

DST PTPRF PTPRQ APBB2 CTNND2

3.89e-0518591532b4e68e551d435a732f253f6ad83408c759a642
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBR3 DST KCND3 PTPRQ WT1

3.89e-051859159197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBR3 DST KCND3 PTPRQ WT1

3.89e-05185915ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellCOVID-19-Endothelial_cells-Systemic_venous_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

TGFBR3 MRTFB SYNE2 BCR GARRE1

3.89e-05185915f5e14181f45c37d13ee9e017a4c8bc248c353676
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL

3.99e-0518691571e87c4c755ab607689cb050f5a363cb520a0f53
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CCDC88A PTPRC FGD2 KCND3 HLA-DOB

3.99e-05186915305f1726b8b5add32f1c29c74991ff34f42e0da7
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 ARHGAP24 PTPRC FGD2 SP110

4.09e-051879158fa454dc4e6a3e8e2bb2ad803acc579e0d3f76da
ToppCelltumor_Lung-T/NK_cells-Cytotoxic_CD8+_T|tumor_Lung / Location, Cell class and cell subclass

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL

4.09e-05187915530839fb53bb285b22919fde6aa16ce1399615ef
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

DST PTPRF PTPRQ APBB2 CTNND2

4.09e-05187915d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Lymphocytic_B-B_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FCHSD2 ARHGAP24 PTPRC FGD2 SP110

4.09e-05187915edad646d5eb1d70b768dc21fe02ef5265214e8e6
ToppCell5'-Adult-LargeIntestine-Hematopoietic-B_cells-Naive_B|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP24 PTPRC FGD2 HLA-DOB SP110

4.09e-0518791557ea69f777420f0671b131c97bcce71d77e29286
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBR3 DST PTPRQ WT1 RAET1E

4.09e-0518791524c2a3962da364e46e98abeab5f8234376fa26bb
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

DST PTPRF PTPRQ APBB2 CTNND2

4.09e-0518791577f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell5'-Adult-Appendix-Hematopoietic-B_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP24 PTPRC FGD2 HLA-DOB SP110

4.20e-051889157b56c680e9f1851cb961b0f8faeeb987685ae36d
ToppCell10x3'2.3-week_14-16-Lymphocytic_B-B_lineage-naive_B_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ARHGAP24 PTPRC FGD2 HLA-DOB SP110

4.20e-0518891531129152386e9aba16f749d78da12a08b916e6f8
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBR3 KCND3 PTPRQ WT1 RAET1E

4.20e-05188915047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCellIPF-Lymphoid-NK|IPF / Disease state, Lineage and Cell class

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL

4.31e-05189915d92e880162450f8d01e4b8784eb625275cb8e03e
ToppCell3'_v3-Lung-Lymphocytic_T_CD8-Tem/emra_CD8|Lung / Manually curated celltypes from each tissue

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL

4.31e-05189915f43bb9db7bb2d19c9849cd3ed892fe3e09e7dfe2
ToppCellCOVID-19-T_cells-NK_cells|COVID-19 / group, cell type (main and fine annotations)

TGFBR3 PTPRC SYNE2 PLCL2 ITGAL

4.31e-05189915b699152dfbb8cd8ed724e1e5a51838f29b681b62
ToppCellwk_15-18-Hematologic_Lymphocytic-B-CD5-_Mature_B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARHGAP24 PTPRC FGD2 HLA-DOB SP110

4.41e-05190915ade43d1d1f8909b8526a23152acf3c26f160f836
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_T/NK-CD8-positive,_alpha-beta_T_cell-CD8_T_cells-CD8_T_cells_L.1.1.4.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL

4.41e-05190915d153a0bdedcd6865e6ee19575234a78b5d859ff1
ToppCellremission-B_memory|World / disease stage, cell group and cell class

SCN11A ARHGAP24 FGD2 HLA-DOB SP110

4.41e-05190915c3f55f752e47b5a71e111367cdbed4a39ab5cb21
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DST PTPRF PTPRQ APBB2 CTNND2

4.41e-0519091530b50d183d7649146eb1e79b47ba897355f1998a
ToppCellCOVID-19-Heart-T_cell|Heart / Disease (COVID-19 only), tissue and cell type

PTPRC GRID2 CSMD1 ITGAL CSMD3

4.41e-05190915e6c3a6e01fef6c5b49f72661d4fb0414ba9046bf
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8-Tem/emra_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL

4.41e-0519091566d29f53f129fc18771f6214316a913eeaccd55e
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

DST KCND3 ACOT11 PLCL2 CTNND2

4.53e-0519191525f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell5'-GW_trimst-2-SmallIntestine-Hematopoietic-B_cells-Immature_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP24 PTPRC FGD2 HLA-DOB SP110

4.53e-051919158c35fccc4617694eae1e55b1107841ffe7f1bac8
ToppCell3'_v3-bone_marrow-Lymphocytic_T_CD8-Tem/emra_CD8|bone_marrow / Manually curated celltypes from each tissue

TGFBR3 PTPRC SYNE2 ARRDC3 ITGAL

4.53e-05191915db7b8f8826bf19d6eeee14319570a9e6e99ab2cb
ToppCellB_cells-Memory_B_cells|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

FCHSD2 ARHGAP24 PTPRC FGD2 HLA-DOB

4.64e-05192915eef591095921ede098f41a2b81897b18915bb753
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL

4.64e-0519291501d01c9293f2439dc4c34c648273319c9beee5c7
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_T-CytoT_GZMH+-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL

4.64e-05192915fdc741e1846cfd8ed741b160e3c611c310c5d36d
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_T-CytoT_GZMH+-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL

4.64e-051929150f8c63de26128694f4522f9f6d029e4628c890bc
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD8|lymph-node_spleen / Manually curated celltypes from each tissue

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL

4.64e-05192915ab88ea7723f0fa3b39611981c043445f27425404
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_T-CytoT_GZMH+-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

TGFBR3 PTPN4 PTPRC SYNE2 ITGAL

4.76e-05193915d66cbb8c71bdc57faecb74a16fe3f34cb0b33228
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TGFBR3 DST PTPRQ WT1 RAET1E

4.76e-051939153eaa0461618582a1754400624350d269d24e750a
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CTNNAL1 MRTFB SPEF2 APBB2 CTNND2

4.76e-051939156e1982d089a9de628e6006d23ff78a223fbd9f47
DiseaseEPILEPSY, FAMILIAL ADULT MYOCLONIC, 1

CTNND2 CNTN2

5.38e-054892C1832841
Diseasehereditary sensory neuropathy (implicated_via_orthology)

SCN11A DST

8.94e-055892DOID:0050548 (implicated_via_orthology)
Diseasecholangiocarcinoma, sclerosing cholangitis

DOCK3 SP110

8.94e-055892EFO_0004268, EFO_0005221
Diseasecysteine-rich secretory protein 2 measurement

CRISP2 CRISP1

2.49e-048892EFO_0801511
Diseaseresponse to carboplatin, response to antineoplastic agent

SPEF2 CSMD1

3.98e-0410892GO_0097327, GO_0097328
Diseaseage at menarche

IQANK1 USP34 DST JADE2 WWP2 DNAH2 CSMD1 PRPF40A

4.35e-04594898EFO_0004703
DiseasePrecursor T-Cell Lymphoblastic Leukemia-Lymphoma

PTPRC MTOR BCR

5.57e-0453893C1961099
Diseasebeta wave measurement

KCND3 RGS21

5.82e-0412892EFO_0006871
Diseasebasophil count, eosinophil count

DOCK3 PTPRC SPEF2 PLCL2 FOSL1

8.29e-04241895EFO_0004842, EFO_0005090
Diseasetype 1 diabetes mellitus

NAA25 PTPRC CFTR DNAH2 RGS21

8.44e-04242895MONDO_0005147
Diseaseschizophrenia (implicated_via_orthology)

MTOR CSMD1 CSMD3

1.15e-0368893DOID:5419 (implicated_via_orthology)
Diseaseheart failure, diabetes mellitus, stroke, atrial fibrillation, mortality, coronary artery disease, cancer

POLR1F DNAH2

1.65e-0320892EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004352, MONDO_0004992
Diseasenicotine dependence symptom count

POLR1F FCHSD2 CLIP2 ARRDC3 CSMD1

1.74e-03285895EFO_0009262
DiseaseGlioblastoma

MTOR WT1 CTNND2

1.78e-0379893C0017636
Diseaseasthma

DOCK3 PTPRC HLA-DOB SPEF2 PLCL2 CTNND2 CSMD3 FOSL1

1.96e-03751898MONDO_0004979
DiseaseGiant Cell Glioblastoma

MTOR WT1 CTNND2

2.12e-0384893C0334588
DiseaseQRS duration, response to sulfonylurea

MDN1 CSMD1

2.18e-0323892EFO_0005055, EFO_0007922
Diseasesevere acute respiratory syndrome, COVID-19

TGFBR3 PTPN4 CATSPERD KCND3 SPEF2 CSMD1

2.36e-03447896EFO_0000694, MONDO_0100096
Diseaseairway responsiveness measurement

IPO8 CSMD1

2.38e-0324892EFO_0006897
Diseaseresponse to TNF antagonist, joint damage measurement

FAR1 CSMD3

2.58e-0325892EFO_0004653, EFO_0005413
DiseaseUterine leiomyoma

DNAH2 WT1 REV1

2.66e-0391893HP_0000131
Diseasetriacylglycerol 48:0 measurement

CTNND2 CSMD1

2.79e-0326892EFO_0010403

Protein segments in the cluster

PeptideGeneStartEntry
LNTSTIMHLWTMDSN

BRINP3

336

Q76B58
LMTSSNKEDWLSVNM

APBB2

616

Q92870
AMNIMSTLQWAVNSS

CFTR

1136

P13569
SAMCTSQPQNWTTMI

CATSPERD

621

Q86XM0
MSNQMWLHLQSDDSI

CSMD1

496

Q96PZ7
VSMSSQMWLHLQTDE

CSMD3

631

Q7Z407
MSTSWSDRLQNAADM

NT5C2

1

P49902
MTDSWSLEVMSQVQV

BCR

1231

P11274
MELSEEHSWMSNQTD

GPR19

41

Q15760
MSNVNLSVSDFWRVM

APTX

1

Q7Z2E3
QIMAWMENVATIAAS

ACOT11

241

Q8WXI4
QATSENMGLMDNWKS

CLIP2

601

Q9UDT6
SNMLKMEWSREVTTN

CRISP2

56

P16562
SMSSMSSAEEQFQWQ

CTNND2

91

Q9UQB3
TSSVSSQCSMNMNWL

ARRDC3

321

Q96B67
SQCSMNMNWLSLSLP

ARRDC3

326

Q96B67
NMLKMSWSEEAAQNA

CRISP1

61

P54107
DAMNMTWTVINHEAS

RAET1E

151

Q8TD07
ATQMVAAQLASMVWN

RBM45

336

Q8IUH3
TWEQGSSMVVMLTTQ

PTPN4

741

P29074
DWVSKIQMMQLQSTD

PATL1

411

Q86TB9
TESTQNNQWTEVMFM

PATL1

706

Q86TB9
NNQWTEVMFMATREL

PATL1

711

Q86TB9
NQESMPSLSFRQTMW

KCND3

156

Q9UK17
QQLQDISSMLWTNMA

MDN1

3106

Q9NU22
SNSWVWNTENVNMLM

FAR1

396

Q8WVX9
QKAQEESSAMMQWLQ

DST

4516

Q03001
SMNDLVQSMVLAGQW

CCDC88A

1491

Q3V6T2
QSVQITAENMAMSEW

JADE2

536

Q9NQC1
SQMWRMINRSNGSEN

GRID2

706

O43424
SWNMSMLQTQDLVKS

ECH1

296

Q13011
SDSNLDNMEWLDITM

MRTFB

1041

Q9ULH7
DNMEWLDITMPNSSS

MRTFB

1046

Q9ULH7
ADAGQTVENMSWMLV

HUWE1

66

Q7Z6Z7
QMVSTMSDGWRFEQL

KCTD17

156

Q8N5Z5
CSVSEDNIMQVWQMA

RBBP4

391

Q09028
SVSEDNIMQIWQMAE

RBBP7

391

Q16576
QNMQCMATSWQSVLV

PTPRQ

1386

Q9UMZ3
MQTAMQISQSWDESL

PABIR2

76

Q7Z309
SNASWEQAMKMIIND

PRPF40A

411

O75400
MRMSTEENRDWLTTQ

FADS2B

386

A8MWK0
MQNRTVVSMLVASWS

GPR149

61

Q86SP6
MASTQNDMEDWVKSI

ARHGAP24

106

Q8N264
MMNLDDKQSIDSATW

ARHGAP24

541

Q8N264
MVRDWVMLSLSNFTQ

HTT

3031

P42858
QNSWLQMADMSVPRS

KLHL15

356

Q96M94
NGDWTFQTVVMLEMT

HLA-DOB

176

P13765
TDTMDSMPSQAWNAD

DOCK3

1911

Q8IZD9
MENNGWVSVTNKDTM

CTNNAL1

716

Q9UBT7
VSTLMVSALQSGWQM

C7orf61

111

Q8IZ16
LWAANENSVQMMRSE

CEP97

456

Q8IW35
TAQMWTQEVFGRQMA

GPR32P1

201

Q8NGA4
QTVSLNMATGMDSWV

C5

586

P01031
TMQMLQSPVWAATND

GARRE1

1011

O15063
SSEMNVTWEPVQQDM

CNTN2

826

Q02246
MLMTQLNSLWNAIDF

FBXL13

186

Q8NEE6
RSQEEMISWMQAFQA

FGD2

401

Q7Z6J4
SVDTWLKSAMNQVME

FCHSD2

401

O94868
NASDQGSWMQLEMLL

C20orf173

111

Q96LM9
DTLWIENMNSVMDDN

DNAH2

2171

Q9P225
SQWLEMVESRQMDES

KIFAP3

681

Q92845
INTMSGSQELQWMVQ

FOSL1

41

P15407
QARMLSASTMLVQWE

PTPRF

421

P10586
VNNQTMTTWMEIFRT

IPO8

221

O15397
TLMREFWVMNTSIQS

MTOR

1036

P42345
TQVSANTMFEMEWRG

FSCN2

326

O14926
FNNMLSGQWTMTNTT

MT-ND2

76

P03891
MLSDISSAMANGNWE

FAN1

611

Q9Y2M0
AMSPWSTQNVDSEMM

RTL9

371

Q8NET4
MTWSENMDTLLANQA

RGS21

16

Q2M5E4
NESWLQDTLGMTMNH

SPEF2

1136

Q9C093
SQWSTMELLQDMSGI

TRIM34

241

Q9BYJ4
VEMGTSSQNDVDMSW

SSR1

241

P43307
QMQSWITRINVVAAM

PSD

856

A5PKW4
TEMISWMNNVEHQTS

SYNE2

5066

Q8WXH0
LASWIMSVLNSMLQS

OR7A10

146

O76100
ESSQDNMRTSWVSQM

PLCL2

261

Q9UPR0
NMRTSWVSQMFSEID

PLCL2

266

Q9UPR0
WLCSGQSNMQMTVLQ

SIAE

121

Q9HAT2
LQMMFNTLVNSSWGD

ITGAL

876

P20701
SWDLSLTEAMLQNME

IQANK1

276

A8MXQ7
TQRKDDSTWNSEVMM

SP110

396

Q9HB58
MTRDQNGTWEMESNE

RBP2

1

P50120
SEATWMEQPNVADTM

NKAPL

261

Q5M9Q1
GMQEIDMSDWQKSTI

WWP2

751

O00308
QDTTHGQEMFWQEMT

ZSCAN30

136

Q86W11
LMQQSVESVWNMAFD

REV1

1216

Q9UBZ9
ISDAMSWLNSKMNAQ

HSPA4L

741

O95757
SQLECMTWNQMNLGA

WT1

231

P19544
TDSNLWTEGMLQMAF

UBR1

901

Q8IWV7
LSAEQWQTMEINMGD

POLR1F

161

Q3B726
MQGQEAVLAMSSRSW

SF3B3

706

Q15393
ENMWECMQEANASSS

SCN11A

771

Q9UI33
DMLENPLNSTQWMND

UBAC1

371

Q9BSL1
QSAARNMADLMWSTV

USP34

286

Q70CQ2
SQVWNMTVSMTSDNS

PTPRC

486

P08575
VLMNAQAWENMMSAS

ZFYVE9

756

O95405
QAWENMMSASSQSPN

ZFYVE9

761

O95405
TSLDASIIWAMMQNK

TGFBR3

731

Q03167
WSVMSLIMQSISAQD

NAA25

151

Q14CX7