Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor	GLUD1 GLUD2	4.01e-05	2	127	2	GO:0016639
GeneOntologyMolecularFunction	glutamate dehydrogenase [NAD(P)+] activity	GLUD1 GLUD2	4.01e-05	2	127	2	GO:0004353
GeneOntologyMolecularFunction	glutamate dehydrogenase (NAD+) activity	GLUD1 GLUD2	4.01e-05	2	127	2	GO:0004352
GeneOntologyMolecularFunction	glutamate dehydrogenase (NADP+) activity	GLUD1 GLUD2	4.01e-05	2	127	2	GO:0004354
GeneOntologyMolecularFunction	taurine:sodium symporter activity	SLC6A6 SLC6A11	1.20e-04	3	127	2	GO:0005369
GeneOntologyMolecularFunction	ATP hydrolysis activity	ERCC6 VPS4A VPS4B FIGNL2 CHD3 RFC4 MMAA MOV10L1 CARNS1 RAD54L VCP	1.20e-04	441	127	11	GO:0016887
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL4A3 HSPG2 COL11A1 LAMA2 FGL2 PRG4 AGRN	2.02e-04	188	127	7	GO:0005201
GeneOntologyMolecularFunction	taurine transmembrane transporter activity	SLC6A6 SLC6A11	3.96e-04	5	127	2	GO:0005368
GeneOntologyMolecularFunction	gamma-aminobutyric acid:sodium:chloride symporter activity	SLC6A6 SLC6A11	5.92e-04	6	127	2	GO:0005332
GeneOntologyMolecularFunction	L-leucine binding	GLUD1 GLUD2	8.25e-04	7	127	2	GO:0070728
GeneOntologyBiologicalProcess	glutamate biosynthetic process	SLC25A12 GLUD1 GLUD2	2.21e-06	5	126	3	GO:0006537
Domain	LamG	HSPG2 FAT4 COL11A1 LAMA2 CNTNAP4 AGRN	4.79e-07	44	126	6	SM00282
Domain	Laminin_G	HSPG2 FAT4 COL11A1 LAMA2 CNTNAP4 AGRN	2.54e-06	58	126	6	IPR001791
Domain	LAM_G_DOMAIN	HSPG2 FAT4 LAMA2 CNTNAP4 AGRN	5.42e-06	38	126	5	PS50025
Domain	Laminin_G_2	HSPG2 FAT4 COL11A1 LAMA2 CNTNAP4	7.03e-06	40	126	5	PF02210
Domain	Vps4_C	VPS4A VPS4B VCP	1.64e-05	8	126	3	IPR015415
Domain	Vps4_C	VPS4A VPS4B VCP	1.64e-05	8	126	3	PF09336
Domain	AAA	VPS4A VPS4B FIGNL2 RFC4 VCP	2.60e-05	52	126	5	PF00004
Domain	ATPase_AAA_core	VPS4A VPS4B FIGNL2 RFC4 VCP	3.13e-05	54	126	5	IPR003959
Domain	MIT	VPS4A VPS4B CAPN7	3.48e-05	10	126	3	SM00745
Domain	MIT	VPS4A VPS4B CAPN7	3.48e-05	10	126	3	PF04212
Domain	-	HSPG2 FAT4 COL11A1 LAMA2 CNTNAP4 AGRN	4.45e-05	95	126	6	2.60.120.200
Domain	ELFV_dehydrog_N	GLUD1 GLUD2	4.52e-05	2	126	2	PF02812
Domain	Glu/Leu/Phe/Val_DH_C	GLUD1 GLUD2	4.52e-05	2	126	2	IPR006096
Domain	Glu/Leu/Phe/Val_DH_dimer_dom	GLUD1 GLUD2	4.52e-05	2	126	2	IPR006097
Domain	Glu/Leu/Phe/Val_DH	GLUD1 GLUD2	4.52e-05	2	126	2	IPR006095
Domain	ELFV_dehydrog	GLUD1 GLUD2	4.52e-05	2	126	2	PF00208
Domain	PIEZO	PIEZO1 PIEZO2	4.52e-05	2	126	2	PF15917
Domain	Piezo	PIEZO1 PIEZO2	4.52e-05	2	126	2	IPR027272
Domain	Piezo_RRas_bdg	PIEZO1 PIEZO2	4.52e-05	2	126	2	PF12166
Domain	NAD_bind_Glu_DH	GLUD1 GLUD2	4.52e-05	2	126	2	IPR033922
Domain	GLFV_DEHYDROGENASE	GLUD1 GLUD2	4.52e-05	2	126	2	PS00074
Domain	ELFV_dehydrog	GLUD1 GLUD2	4.52e-05	2	126	2	SM00839
Domain	Glu/Leu/Phe/Val_DH_AS	GLUD1 GLUD2	4.52e-05	2	126	2	IPR033524
Domain	Piezo_RRas-bd_dom	PIEZO1 PIEZO2	4.52e-05	2	126	2	IPR031334
Domain	Piezo_dom	PIEZO1 PIEZO2	4.52e-05	2	126	2	IPR031805
Domain	Laminin_G_1	HSPG2 LAMA2 AGRN	4.75e-05	11	126	3	PF00054
Domain	AAA	VPS4A VPS4B FIGNL2 VCP	7.83e-05	34	126	4	PS00674
Domain	-	VPS4A VPS4B CAPN7	8.16e-05	13	126	3	1.20.58.280
Domain	MIT	VPS4A VPS4B CAPN7	1.03e-04	14	126	3	IPR007330
Domain	UBA	UBAP2 MARK3 NACA USP5	2.81e-04	47	126	4	PS50030
Domain	AAA	VPS4A VPS4B FIGNL2 RFC4 MMAA VCP	4.36e-04	144	126	6	SM00382
Domain	AAA+_ATPase	VPS4A VPS4B FIGNL2 RFC4 MMAA VCP	4.36e-04	144	126	6	IPR003593
Domain	-	CHD3 CIC KMT2D SOX21	5.16e-04	55	126	4	1.10.30.10
Domain	ConA-like_dom	HSPG2 FAT4 COL11A1 LAMA2 RYR3 CNTNAP4 AGRN	7.19e-04	219	126	7	IPR013320
Domain	AT_hook	AHCTF1 AHDC1 PRR12	7.79e-04	27	126	3	SM00384
Domain	AT_hook_DNA-bd_motif	AHCTF1 AHDC1 PRR12	7.79e-04	27	126	3	IPR017956
Domain	CUT	CUX2 ONECUT3	9.27e-04	7	126	2	PS51042
Domain	CUT	CUX2 ONECUT3	9.27e-04	7	126	2	PF02376
Domain	CUT_dom	CUX2 ONECUT3	9.27e-04	7	126	2	IPR003350
Domain	CUT	CUX2 ONECUT3	9.27e-04	7	126	2	SM01109
Domain	ATPase_AAA_CS	VPS4A VPS4B VCP	9.64e-04	29	126	3	IPR003960
Domain	HMG_box_dom	CHD3 CIC KMT2D SOX21	9.73e-04	65	126	4	IPR009071
Domain	UBA	UBAP2 MARK3 USP5	1.07e-03	30	126	3	SM00165
Domain	EGF_LAM_2	HSPG2 LAMA2 AGRN	1.07e-03	30	126	3	PS50027
Domain	EGF_LAM_1	HSPG2 LAMA2 AGRN	1.07e-03	30	126	3	PS01248
Domain	HEMATOPO_REC_S_F1	CSF2RB IL4R	1.23e-03	8	126	2	PS01355
Domain	LAMININ_IVA	HSPG2 LAMA2	1.23e-03	8	126	2	PS51115
Domain	Laminin_B	HSPG2 LAMA2	1.23e-03	8	126	2	PF00052
Domain	LamB	HSPG2 LAMA2	1.23e-03	8	126	2	SM00281
Domain	Laminin_IV	HSPG2 LAMA2	1.23e-03	8	126	2	IPR000034
Domain	SNF2_N	ERCC6 CHD3 RAD54L	1.29e-03	32	126	3	IPR000330
Domain	SNF2_N	ERCC6 CHD3 RAD54L	1.29e-03	32	126	3	PF00176
Domain	Hempt_rcpt_S_F1_CS	CSF2RB IL4R	1.58e-03	9	126	2	IPR003531
Domain	EGF_Lam	HSPG2 LAMA2 AGRN	1.68e-03	35	126	3	SM00180
Domain	Laminin_EGF	HSPG2 LAMA2 AGRN	1.68e-03	35	126	3	PF00053
Domain	UBA	UBAP2 MARK3 USP5	1.82e-03	36	126	3	PF00627
Domain	Laminin_EGF	HSPG2 LAMA2 AGRN	2.13e-03	38	126	3	IPR002049
Domain	calpain_III	CAPN8 CAPN7	2.85e-03	12	126	2	SM00720
Domain	C2_III	CAPN8 CAPN7	2.85e-03	12	126	2	IPR033883
Domain	Calpain_III	CAPN8 CAPN7	2.85e-03	12	126	2	IPR022683
Domain	UBA	UBAP2 MARK3 USP5	3.24e-03	44	126	3	IPR015940
Domain	Calpain_III	CAPN8 CAPN7	3.35e-03	13	126	2	PF01067
Domain	Calpain_domain_III	CAPN8 CAPN7	3.35e-03	13	126	2	IPR022682
Domain	SET	PRDM8 KMT2D PRDM6	3.68e-03	46	126	3	SM00317
Domain	SEA	HSPG2 AGRN	3.90e-03	14	126	2	SM00200
Domain	Calpain_cysteine_protease	CAPN8 CAPN7	3.90e-03	14	126	2	IPR022684
Domain	Peptidase_C2	CAPN8 CAPN7	4.48e-03	15	126	2	PF00648
Domain	CysPc	CAPN8 CAPN7	4.48e-03	15	126	2	SM00230
Domain	Peptidase_C2_calpain_cat	CAPN8 CAPN7	4.48e-03	15	126	2	IPR001300
Domain	CALPAIN_CAT	CAPN8 CAPN7	4.48e-03	15	126	2	PS50203
Domain	SET_dom	PRDM8 KMT2D PRDM6	4.66e-03	50	126	3	IPR001214
Domain	SET	PRDM8 KMT2D PRDM6	4.66e-03	50	126	3	PS50280
Domain	AT_hook	AHCTF1 PRR12	5.09e-03	16	126	2	PF02178
Domain	HMG_box	CIC KMT2D SOX21	5.49e-03	53	126	3	PF00505
Domain	HMG	CIC KMT2D SOX21	5.79e-03	54	126	3	SM00398
Domain	NA_NEUROTRAN_SYMP_2	SLC6A6 SLC6A11	6.44e-03	18	126	2	PS00754
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	COL4A3 HSPG2 COL11A1 LAMA2 AGRN	3.62e-05	59	90	5	M27218
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TET2 RGPD2 TTC28 VPS4B TNRC6B CHD3 CIC RBM20 SFMBT2 PALB2 BAP1 PRR12 KMT2D TLE3 ZBTB10	5.29e-11	418	129	15	34709266
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	DPH2 HSPG2 SHROOM3 PIEZO1 NOB1 ZBTB4 AHDC1 CIC BAP1 PRR12 KMT2D ZFP36L2 KCNH2 TMCC2 SCN8A TNFAIP3 AGRN IL4R CRAMP1 PRRC2B BAHCC1	8.21e-10	1105	129	21	35748872
Pubmed	The mutational landscape of cutaneous T cell lymphoma and Sézary syndrome.	TET2 CHD3 KMT2D	4.99e-08	3	129	3	26551667
Pubmed	Piezo2 channels expressed by colon-innervating TRPV1-lineage neurons mediate visceral mechanical hypersensitivity.	TRPV1 PIEZO1 PIEZO2	1.99e-07	4	129	3	36563677
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TET2 SHROOM3 UBAP2 PITRM1 PIEZO1 NACA HEPH BAP1 UNK CARNS1 CRAMP1 MGRN1	7.08e-07	529	129	12	14621295
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TET2 CHD3 AHDC1 CIC BAP1 PRR12 KMT2D TLE3 PRRC2B	7.67e-07	268	129	9	33640491
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	AHCTF1 TNRC6B AHDC1 CIC RBM20 PRR12 KMT2D TLE3 GLUD1 PRORP PRRC2B	1.18e-06	457	129	11	32344865
Pubmed	Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice.	HSPG2 LAMA2 AGRN	1.73e-06	7	129	3	11802174
Pubmed	The Piezo channel is a mechano-sensitive complex component in the mammalian inner ear hair cell.	TRPV1 PIEZO1 PIEZO2	2.75e-06	8	129	3	38228630
Pubmed	Dietary excess regulates absorption and surface of gut epithelium through intestinal PPARα.	LGR5 GLUD1 GLUD2	2.75e-06	8	129	3	34857752
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ERCC6 PSD TTC28 VPS4A AHCTF1 TNRC6B CHD3 RFC4 PLEKHN1 ZNF469 SLC25A12 ZBTB10 CSMD1 PRRC2B VCP BAHCC1	4.05e-06	1116	129	16	31753913
Pubmed	Human transcription factor protein interaction networks.	TET2 HSPG2 UBAP2 PITRM1 NACA TNRC6B CHD3 CIC RBM20 BAP1 PRR12 KMT2D TLE3 GLUD1 ZSCAN18 ZBTB10 UNK PRRC2B	5.84e-06	1429	129	18	35140242
Pubmed	Interaction network of human early embryonic transcription factors.	TET2 AHDC1 PRR12 KMT2D TLE3 GLUD1 PRDM6 PRRC2B BAHCC1	6.94e-06	351	129	9	38297188
Pubmed	A Metabolite-Triggered Tuft Cell-ILC2 Circuit Drives Small Intestinal Remodeling.	LGR5 TNFAIP3 IL4R	8.05e-06	11	129	3	29887373
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	HSPG2 LAMA2 AGRN	1.07e-05	12	129	3	16750824
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL4A3 HSPG2 COL11A1 LAMA2 C1QB AGRN	1.18e-05	135	129	6	28675934
Pubmed	Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors.	GLUD1 GLUD2	1.37e-05	2	129	2	34173171
Pubmed	Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.	GLUD1 GLUD2	1.37e-05	2	129	2	28621566
Pubmed	Agrin and perlecan mediate tumorigenic processes in oral squamous cell carcinoma.	HSPG2 AGRN	1.37e-05	2	129	2	25506919
Pubmed	Phosphatidylethanolamine, a limiting factor of autophagy in yeast strains bearing a defect in the carboxypeptidase Y pathway of vacuolar targeting.	VPS4A VPS4B	1.37e-05	2	129	2	17428789
Pubmed	GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.	GLUD1 GLUD2	1.37e-05	2	129	2	32078638
Pubmed	[Feeling the pressure? Identification of two proteins activated by mechanical forces].	PIEZO1 PIEZO2	1.37e-05	2	129	2	21299953
Pubmed	Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter.	GLUD1 GLUD2	1.37e-05	2	129	2	23595828
Pubmed	Identification of pauses during formation of HIV-1 virus like particles.	VPS4A VPS4B	1.37e-05	2	129	2	24268138
Pubmed	Cloning, characterisation, and functional expression of the Mus musculus SKD1 gene in yeast demonstrates that the mouse SKD1 and the yeast VPS4 genes are orthologues and involved in intracellular protein trafficking.	VPS4A VPS4B	1.37e-05	2	129	2	10393249
Pubmed	Piezo1 expression in chondrocytes controls endochondral ossification and osteoarthritis development.	PIEZO1 PIEZO2	1.37e-05	2	129	2	38395992
Pubmed	MicroRNA Let-7c-5p-Mediated Regulation of ERCC6 Disrupts Autophagic Flux in Age-Related Cataract via the Binding to VCP.	ERCC6 VCP	1.37e-05	2	129	2	33703976
Pubmed	Differential expression of PIEZO1 and PIEZO2 mechanosensitive channels in ocular tissues implicates diverse functional roles.	PIEZO1 PIEZO2	1.37e-05	2	129	2	37820892
Pubmed	Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.	GLUD1 GLUD2	1.37e-05	2	129	2	21621574
Pubmed	Mechanisms of mechanotransduction and physiological roles of PIEZO channels.	PIEZO1 PIEZO2	1.37e-05	2	129	2	39251883
Pubmed	Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.	GLUD1 GLUD2	1.37e-05	2	129	2	28911206
Pubmed	Immunolocalization of the mechanogated ion channels PIEZO1 and PIEZO2 in human and mouse dental pulp and periodontal ligament.	PIEZO1 PIEZO2	1.37e-05	2	129	2	37975162
Pubmed	Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.	GLUD1 GLUD2	1.37e-05	2	129	2	22875990
Pubmed	Influenza virus budding does not require a functional AAA+ ATPase, VPS4.	VPS4A VPS4B	1.37e-05	2	129	2	20621136
Pubmed	Transduction of Repetitive Mechanical Stimuli by Piezo1 and Piezo2 Ion Channels.	PIEZO1 PIEZO2	1.37e-05	2	129	2	28636944
Pubmed	Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.	GLUD1 GLUD2	1.37e-05	2	129	2	15578726
Pubmed	Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	1.37e-05	2	129	2	15044002
Pubmed	Induction of excitatory and inhibitory presynaptic differentiation by GluD1.	GLUD1 GLUD2	1.37e-05	2	129	2	22138648
Pubmed	Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia.	GLUD1 GLUD2	1.37e-05	2	129	2	34220417
Pubmed	Piezo channels: from structure to function.	PIEZO1 PIEZO2	1.37e-05	2	129	2	25037583
Pubmed	Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues.	GLUD1 GLUD2	1.37e-05	2	129	2	26241911
Pubmed	Comparative sequence and expression analyses of four mammalian VPS4 genes.	VPS4A VPS4B	1.37e-05	2	129	2	12594041
Pubmed	Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum.	GLUD1 GLUD2	1.37e-05	2	129	2	21446915
Pubmed	Amelioration of laminin-alpha2-deficient congenital muscular dystrophy by somatic gene transfer of miniagrin.	LAMA2 AGRN	1.37e-05	2	129	2	16103356
Pubmed	The VPS4 gene is involved in protein transport out of a yeast pre-vacuolar endosome-like compartment.	VPS4A VPS4B	1.37e-05	2	129	2	9211789
Pubmed	GluD1 binds GABA and controls inhibitory plasticity.	GLUD1 GLUD2	1.37e-05	2	129	2	38060673
Pubmed	Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice.	GLUD1 GLUD2	1.37e-05	2	129	2	24593767
Pubmed	The role of PIEZO ion channels in the musculoskeletal system.	PIEZO1 PIEZO2	1.37e-05	2	129	2	36717101
Pubmed	Potentiation of neuronal activity by tonic GluD1 current in brain slices.	GLUD1 GLUD2	1.37e-05	2	129	2	37154294
Pubmed	Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.	GLUD1 GLUD2	1.37e-05	2	129	2	22924626
Pubmed	Mammalian cells express two VPS4 proteins both of which are involved in intracellular protein trafficking.	VPS4A VPS4B	1.37e-05	2	129	2	11563910
Pubmed	Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.	GLUD1 GLUD2	1.37e-05	2	129	2	11032875
Pubmed	A Plug-and-Latch Mechanism for Gating the Mechanosensitive Piezo Channel.	PIEZO1 PIEZO2	1.37e-05	2	129	2	32142647
Pubmed	Effects of the curly tail genotype on neuroepithelial integrity and cell proliferation during late stages of primary neurulation.	HSPG2 GRHL3	1.37e-05	2	129	2	11787818
Pubmed	Functional roles for PIEZO1 and PIEZO2 in urothelial mechanotransduction and lower urinary tract interoception.	PIEZO1 PIEZO2	1.37e-05	2	129	2	34464353
Pubmed	Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes.	GLUD1 GLUD2	1.37e-05	2	129	2	29943084
Pubmed	Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.	GLUD1 GLUD2	1.37e-05	2	129	2	31898404
Pubmed	Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.	GLUD1 GLUD2	1.37e-05	2	129	2	15378063
Pubmed	Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions.	GLUD1 GLUD2	1.37e-05	2	129	2	27422263
Pubmed	Synthetic lethality between VPS4A and VPS4B triggers an inflammatory response in colorectal cancer.	VPS4A VPS4B	1.37e-05	2	129	2	31930723
Pubmed	Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes.	GLUD1 GLUD2	1.37e-05	2	129	2	15750346
Pubmed	Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA.	GLUD1 GLUD2	1.37e-05	2	129	2	1711373
Pubmed	Three-dimensional structure of AAA ATPase Vps4: advancing structural insights into the mechanisms of endosomal sorting and enveloped virus budding.	VPS4A VPS4B	1.37e-05	2	129	2	19278657
Pubmed	Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate.	GLUD1 GLUD2	1.37e-05	2	129	2	20529287
Pubmed	Determination of glutamate dehydrogenase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry).	GLUD1 GLUD2	1.37e-05	2	129	2	25124006
Pubmed	Unexpected histone H3 tail-clipping activity of glutamate dehydrogenase.	GLUD1 GLUD2	1.37e-05	2	129	2	23673664
Pubmed	Lack of evidence for direct ligand-gated ion channel activity of GluD receptors.	GLUD1 GLUD2	1.37e-05	2	129	2	39052831
Pubmed	Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice.	GLUD1 GLUD2	1.37e-05	2	129	2	24442550
Pubmed	The Amplifying Pathway of the β-Cell Contributes to Diet-induced Obesity.	GLUD1 GLUD2	1.37e-05	2	129	2	27137930
Pubmed	GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution.	GLUD1 GLUD2	1.37e-05	2	129	2	26440896
Pubmed	Study of structure-function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme.	GLUD1 GLUD2	1.37e-05	2	129	2	12742085
Pubmed	Piezo proteins: incidence and abundance in the enteric nervous system. Is there a link with mechanosensitivity?	PIEZO1 PIEZO2	1.37e-05	2	129	2	30324494
Pubmed	Analysis of individual HIV-1 budding event using fast AFM reveals a multiplexed role for VPS4.	VPS4A VPS4B	1.37e-05	2	129	2	36042696
Pubmed	Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection.	GLUD1 GLUD2	1.37e-05	2	129	2	18688271
Pubmed	Synthetic Lethal Interaction between the ESCRT Paralog Enzymes VPS4A and VPS4B in Cancers Harboring Loss of Chromosome 18q or 16q.	VPS4A VPS4B	1.37e-05	2	129	2	33326793
Pubmed	The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology.	GLUD1 GLUD2	1.37e-05	2	129	2	22658952
Pubmed	Mechanosensitive channels: in touch with Piezo.	PIEZO1 PIEZO2	1.37e-05	2	129	2	21056836
Pubmed	Loss of stretch-activated channels, PIEZOs, accelerates non-small cell lung cancer progression and cell migration.	PIEZO1 PIEZO2	1.37e-05	2	129	2	30745454
Pubmed	TET2 and CSMD1 genes affect SBP response to hydrochlorothiazide in never-treated essential hypertensives.	TET2 CSMD1	1.37e-05	2	129	2	25695618
Pubmed	Increases in anterograde axoplasmic transport in neurons of the hyper-glutamatergic, glutamate dehydrogenase 1 (Glud1) transgenic mouse: Effects of glutamate receptors on transport.	GLUD1 GLUD2	1.37e-05	2	129	2	38124277
Pubmed	Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.	GLUD1 GLUD2	1.37e-05	2	129	2	19015267
Pubmed	Astrocytes in the optic nerve head express putative mechanosensitive channels.	PIEZO1 PIEZO2	1.37e-05	2	129	2	26236150
Pubmed	Touch, Tension, and Transduction - The Function and Regulation of Piezo Ion Channels.	PIEZO1 PIEZO2	1.37e-05	2	129	2	27743844
Pubmed	Axonal and Glial PIEZO1 and PIEZO2 Immunoreactivity in Human Clitoral Krause's Corpuscles.	PIEZO1 PIEZO2	1.37e-05	2	129	2	38928429
Pubmed	A hydrophobic gate in the inner pore helix is the major determinant of inactivation in mechanosensitive Piezo channels.	PIEZO1 PIEZO2	1.37e-05	2	129	2	30628892
Pubmed	Piezo1 ion channel pore properties are dictated by C-terminal region.	PIEZO1 PIEZO2	1.37e-05	2	129	2	26008989
Pubmed	Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.	GLUD1 GLUD2	1.37e-05	2	129	2	19448744
Pubmed	Piezo1 and Piezo2 are essential components of distinct mechanically activated cation channels.	PIEZO1 PIEZO2	1.37e-05	2	129	2	20813920
Pubmed	Genetic variations in A20 DUB domain provide a genetic link to citrullination and neutrophil extracellular traps in systemic lupus erythematosus.	USP5 TNFAIP3	1.37e-05	2	129	2	31300459
Pubmed	Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.	GLUD1 GLUD2	1.37e-05	2	129	2	11950837
Pubmed	Somatic mutations in KMT2D and TET2 associated with worse prognosis in Epstein-Barr virus-associated T or natural killer-cell lymphoproliferative disorders.	TET2 KMT2D	1.37e-05	2	129	2	31311407
Pubmed	Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains.	USP5 TNFAIP3 USP15	1.39e-05	13	129	3	19373254
Pubmed	Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.	COL4A3 HSPG2 AGRN	1.39e-05	13	129	3	12682087
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	CHD3 CIC PRR12 KMT2D TLE3	1.50e-05	83	129	5	28794006
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CUX2 TTC28 TNRC6B HEPH BAP1 TMCC2 USP15	2.21e-05	225	129	7	12168954
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	UBAP2 TTC28 MARK3 VPS4A VPS4B RFC4 BAP1 USP5 TNFAIP3 ALDH9A1 USP15 RPL3L PRRC2B VCP	2.32e-05	1005	129	14	19615732
Pubmed	Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.	HSPG2 LAMA2 AGRN	2.69e-05	16	129	3	17948866
Pubmed	Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne.	USP5 TNFAIP3 USP15	3.26e-05	17	129	3	20622874
Pubmed	A census of human transcription factors: function, expression and evolution.	CUX2 NKX6-2 AHCTF1 ZBTB4 CIC KMT2D FOXL2 SOX21 ZFP36L2 DLX4 GRHL3 ONECUT3 CRAMP1	3.49e-05	908	129	13	19274049
Pubmed	Microautophagy of cytosolic proteins by late endosomes.	VPS4A VPS4B	4.09e-05	3	129	2	21238931
Interaction	SOX7 interactions	TET2 RBM20 PRR12 KMT2D SOX21 TLE3 BAHCC1	9.05e-07	82	128	7	int:SOX7
Interaction	SP7 interactions	TET2 PITRM1 CHD3 CIC RBM20 PRR12 KMT2D TLE3 GLUD1 DLX4 PRRC2B	3.91e-06	304	128	11	int:SP7
Interaction	KLF5 interactions	TET2 CIC RBM20 BAP1 PRR12 KMT2D TLE3 ZBTB10 PRRC2B	4.37e-06	195	128	9	int:KLF5
Interaction	GCM1 interactions	TET2 CIC PRR12 KMT2D TLE3 PRRC2B	4.63e-06	68	128	6	int:GCM1
Interaction	TLE3 interactions	TET2 ZBTB4 AHDC1 CIC RBM20 BAP1 PRR12 KMT2D CAPN7 TLE3 ZSCAN18 VCP	5.08e-06	376	128	12	int:TLE3
Interaction	TBR1 interactions	TET2 CIC BAP1 PRR12 KMT2D TLE3 USP15	7.81e-06	113	128	7	int:TBR1
Interaction	TOP3B interactions	DPH2 HSPG2 SHROOM3 UBAP2 PIEZO1 NOB1 ZBTB4 TNRC6B AHDC1 CIC BAP1 PRR12 KMT2D ZFP36L2 KCNH2 TMCC2 SCN8A UNK TNFAIP3 AGRN IL4R CRAMP1 PRRC2B BAHCC1	1.61e-05	1470	128	24	int:TOP3B
Interaction	CAPRIN1 interactions	UBAP2 MARK3 TNRC6B CHD3 RFC4 BAP1 ZFP36L2 GLUD1 ZBTB10 UNK PRRC2B VCP	3.10e-05	451	128	12	int:CAPRIN1
Interaction	TTR interactions	HSPG2 MARK3 CHD3 NGFR TNFAIP3 VCP	4.27e-05	100	128	6	int:TTR
Interaction	CSTF1 interactions	ERCC6 CIC ZBTB10 ALDH9A1 USP15 VCP	5.32e-05	104	128	6	int:CSTF1
Interaction	PAX8 interactions	TET2 CIC PRR12 KMT2D TLE3 PRRC2B	7.66e-05	111	128	6	int:PAX8
Interaction	KDM1A interactions	TET2 TTC28 VPS4B TNRC6B CHD3 CIC RBM20 SFMBT2 PALB2 BAP1 PRR12 KMT2D SLC4A1AP TLE3 ZBTB10 UNK USP15	9.65e-05	941	128	17	int:KDM1A
GeneFamily	AAA ATPases	VPS4A VPS4B FIGNL2 RFC4 VCP	4.36e-06	53	83	5	413
GeneFamily	AAA ATPases\|ESCRT-IV	VPS4A VPS4B	6.23e-05	3	83	2	1120
GeneFamily	Blood group antigens\|CD molecules\|Proteoglycans	HSPG2 AGRN	4.31e-04	7	83	2	570
GeneFamily	Zinc fingers C2H2-type\|Lysine methyltransferases\|PR/SET domain family	PRDM8 KMT2D PRDM6	5.04e-04	34	83	3	487
GeneFamily	CUT class homeoboxes and pseudogenes	CUX2 ONECUT3	7.34e-04	9	83	2	527
GeneFamily	C2 domain containing\|Calpains	CAPN8 CAPN7	2.10e-03	15	83	2	975
GeneFamily	Zinc fingers C2H2-type\|PR/SET domain family	PRDM8 PRDM6	2.71e-03	17	83	2	1197
Coexpression	GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_DN	COL4A3 FIGNL2 LAMA2 NFKBIZ FGL2 ZFP36L2 GLUD1 TNFAIP3	2.08e-06	170	129	8	M9445
Coexpression	DASU_IL6_SIGNALING_SCAR_UP	CIC ZFP36L2 AGRN MGRN1	1.59e-05	31	129	4	M292
ToppCell	3'-Adult-LargeIntestine-Hematopoietic-Plasma_cells-IgG_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL4A3 RGPD2 PIM2 MYCBPAP SFMBT2 CSF2RB TNFAIP3 SPOCD1	4.56e-08	175	129	8	c3d3f11602379aaba65842a98835299e54fccd84
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 COL11A1 RYR3 CAPN8 PIEZO2 CNTNAP4 CSMD1 ONECUT3	6.72e-08	184	129	8	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 COL11A1 RYR3 CAPN8 PIEZO2 CNTNAP4 CSMD1 ONECUT3	6.72e-08	184	129	8	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT4 COL11A1 RYR3 CAPN8 PIEZO2 CNTNAP4 CSMD1 ONECUT3	6.72e-08	184	129	8	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ENDOD1 NKX6-2 SLC6A6 PIEZO2 TMCC2 NGFR CNTNAP4 CARNS1	1.14e-07	197	129	8	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 MUC19 LAMA2 RYR3 CAPN8 MOV10L1 CNTNAP4	4.38e-07	160	129	7	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 MUC19 LAMA2 RYR3 CAPN8 MOV10L1 CNTNAP4	4.38e-07	160	129	7	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 TET2 CR1 SFMBT2 RYR3 LCNL1 IQCJ-SCHIP1	1.08e-06	183	129	7	eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell	COVID-19_Severe-Neu_1\|COVID-19_Severe / 5 Neutrophil clusters in COVID-19 patients	TET2 NFKBIZ CR1 FGL2 CSF2RB TNFAIP3 IL4R	1.83e-06	198	129	7	bbe639ea5a636c985e509fb0a133ae3b60afac5a
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 LAMA2 HEPH ZNF469 PIEZO2 PRG4 PRDM6	1.89e-06	199	129	7	21335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCell	COVID-19_Severe-Neu_1\|World / 5 Neutrophil clusters in COVID-19 patients	TET2 NFKBIZ CR1 FGL2 CSF2RB TNFAIP3 IL4R	1.89e-06	199	129	7	e4d8bf016fd95a440e30014a75587e097e90cfad
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Mesenchymal-BMP_responsible_cell\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	PIEZO1 OAS1 NFKBIZ SFMBT2 ZFP36L2 BST1 IL4R	1.95e-06	200	129	7	26251ed8c7fa7e87973d6f59bd398c88ad025395
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Macroglial-Glia_progenitor_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	TGFBR3L NFKBIZ SFMBT2 FGL2 ZNF469 EEPD1 TNFAIP3	1.95e-06	200	129	7	4b937b1d0179d1d0e51931f35720e205d460a07e
ToppCell	356C-Fibroblasts-Fibroblast-H-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TRPV1 VPS4A PALB2 GLUD2 UGT2B4 MGRN1	5.24e-06	151	129	6	2dc132895609e4efe17954e31f53d9c1ccf256ef
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8\|TCGA-Thymus / Sample_Type by Project: Shred V9	COL4A3 FAT4 COL11A1 LGR5 PIEZO2 PRG4	5.24e-06	151	129	6	5906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCell	356C-Fibroblasts-Fibroblast-H\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	TRPV1 VPS4A PALB2 GLUD2 UGT2B4 MGRN1	5.24e-06	151	129	6	22afd8201eff8471da3456be065f2790de5e4bfe
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell-D231\|Adult / Lineage, Cell type, age group and donor	MYOM1 RYR3 SLC6A11 MN1 PRDM6 RAD54L	7.30e-06	160	129	6	d783d29150033e9181c0e30870070268fed3fd85
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CUX2 COL11A1 CPNE9 LAMA2 PRDM8 IQCJ-SCHIP1	1.03e-05	170	129	6	985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCell	facs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM234B FBXW10 ERCC6 TGFBR3L ZSCAN18 BAHCC1	1.03e-05	170	129	6	d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell	356C-Myeloid-Dendritic-cDC_activated\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	CHD3 PIEZO2 CSF2RB TMCC2 NGFR ONECUT3	1.03e-05	170	129	6	513d9036aa41d4d902da8baa66a66206abb6f3b0
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SHROOM3 CUX2 CPNE9 RYR3 PRDM8 IQCJ-SCHIP1	1.18e-05	174	129	6	ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell	COVID-19-kidney-Podocyte\|kidney / Disease (COVID-19 only), tissue and cell type	COL4A3 CR1 SFMBT2 RYR3 LCNL1 IQCJ-SCHIP1	1.57e-05	183	129	6	fb5e2a31b560126e1c04a386c24c365901c60ad7
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 CR1 SFMBT2 RYR3 LCNL1 IQCJ-SCHIP1	1.57e-05	183	129	6	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 CR1 SFMBT2 RYR3 LCNL1 IQCJ-SCHIP1	1.57e-05	183	129	6	7c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MUC19 FGL2 CNTNAP4 SIGLEC11 CSMD1 USP15	1.72e-05	186	129	6	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	mild_COVID-19_(asymptomatic)-Non-classical_Monocyte\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	PIEZO1 OAS1 NFKBIZ SFMBT2 FGL2 C1QB	2.12e-05	193	129	6	7839040e703877ef321494ad8926a8604729ceda
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ENDOD1 NKX6-2 TMCC2 NGFR CNTNAP4 CARNS1	2.12e-05	193	129	6	947200ef6c3a2e35ad7e6b4af29d92384bdf73f5
ToppCell	(5)_Fibroblast-C_(Myofibroblast)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	LAMA2 HEPH PIEZO2 UGT2B4 PRG4 PRDM6	2.18e-05	194	129	6	29a72e565c19407bbd198cfbc2a78106fe830d05
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SHROOM3 MUC19 NFKBIZ RYR3 TNFAIP3 CSMD1	2.24e-05	195	129	6	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	SHROOM3 MUC19 NFKBIZ RYR3 TNFAIP3 CSMD1	2.24e-05	195	129	6	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	Control-Classical_Monocyte-cMono_2\|Control / Disease condition and Cell class	NFKBIZ FGL2 ZFP36L2 BST1 TNFAIP3 USP15	2.24e-05	195	129	6	0fea64ee3eedf3929abb0dd9c5f5fc72f181eed9
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NFKBIZ CR1 FGL2 CSF2RB BST1 TNFAIP3	2.31e-05	196	129	6	f811958823380069077754283e36106d80147494
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 LAMA2 LGR5 MOV10L1 MN1 PRDM6	2.38e-05	197	129	6	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	COL11A1 LAMA2 AHDC1 FGL2 LCNL1 NGFR	2.38e-05	197	129	6	2cb1f557ce1400398975de94638126b4522567f3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NFKBIZ CR1 FGL2 CSF2RB BST1 TNFAIP3	2.38e-05	197	129	6	4d3670456655248250d156f92de01df4aa481733
ToppCell	BL\|World / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	NFKBIZ CR1 CSF2RB TNFAIP3 USP15 IL4R	2.38e-05	197	129	6	1acf0191fa0a25cd20bfd9ea7bf727a1555986a1
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Myeloid-Microglia\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	PIEZO1 OAS1 SFMBT2 CSF2RB C1QB IL4R	2.44e-05	198	129	6	901cd39cb84f1907f2f5d27221979c854bd3b40e
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW16-Myeloid\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	PIEZO1 OAS1 SFMBT2 CSF2RB C1QB IL4R	2.44e-05	198	129	6	cc292aa8518d5ef8940e2327f2f07d584a996d90
ToppCell	Transverse-B_cell-B_cell_IgG_Plasma\|Transverse / Region, Cell class and subclass	CHIA PIM2 TBC1D30 ST6GAL1 CSF2RB MOV10L1	2.44e-05	198	129	6	a4ece1fe3d15acfde0e6ff14cddb3a3d16f61ce0
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 ST6GAL1 FGL2 CAPN8 ZFP36L2 AGRN	2.44e-05	198	129	6	0d9d401190792fd61434f1b82548253187d805f0
ToppCell	Transverse-(2)_B_cell-(21)_B_cell_IgG_Plasma\|Transverse / shred on region, Cell_type, and subtype	CHIA PIM2 TBC1D30 ST6GAL1 CSF2RB MOV10L1	2.44e-05	198	129	6	d6052b5a44246798e90f4779cd940ffac7539fcd
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD4_INF-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ENDOD1 PIM2 OAS1 NFKBIZ ZFP36L2 TNFAIP3	2.51e-05	199	129	6	d3f36ede2fade550ec8f21a0448e71e1ff579ee2
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ENDOD1 NKX6-2 PIEZO2 TMCC2 CNTNAP4 CARNS1	2.51e-05	199	129	6	214a6a267e77e5508867b9eb48c4fbc7855ed0a0
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYOM1 NFKBIZ PIEZO2 CNTNAP4 MN1 AGRN	2.51e-05	199	129	6	eeb7d370d4dfacf705306c72ccc4919ddefacff1
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-FILIP1L\|Neuronal / cells hierarchy compared to all cells using T-Statistic	IQANK1 CUX2 COL11A1 LAMA2 PRDM8 IQCJ-SCHIP1	2.59e-05	200	129	6	f6af5ef02625aaae21e885e1ebd195e34731e53a
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-FILIP1L-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	IQANK1 CUX2 COL11A1 LAMA2 PRDM8 IQCJ-SCHIP1	2.59e-05	200	129	6	53f61e28c3ad6399f63c54e06120ecb5ebbf90d9
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ENDOD1 NKX6-2 PIEZO2 TMCC2 CNTNAP4 CARNS1	2.59e-05	200	129	6	acdef0b9096c774040948fc75621ff2b08ea2ee8
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-FILIP1L--L3-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	IQANK1 CUX2 COL11A1 LAMA2 PRDM8 IQCJ-SCHIP1	2.59e-05	200	129	6	c1f243ae929f7791e040437470033abf749b44cc
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ENDOD1 NKX6-2 PIEZO2 TMCC2 CNTNAP4 CARNS1	2.59e-05	200	129	6	091a18d6efed81cab99955c3047f172170f70476
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-Oligodendrocyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ENDOD1 NKX6-2 PIEZO2 TMCC2 CNTNAP4 CARNS1	2.59e-05	200	129	6	3b8513defe25262ab4b492345b2628570eaefd17
ToppCell	Biopsy_IPF-Mesenchymal-Myofibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	FAT4 LAMA2 HEPH PIEZO2 PRG4 PRDM6	2.59e-05	200	129	6	c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCell	PBMC-Severe-cDC_3\|Severe / Compartment, Disease Groups and Clusters	PSD MYOM1 SKIDA1 NGFR CFAP74	8.10e-05	152	129	5	1a3f8ed476aa9a39742b4684be2c704669e4a3d0
ToppCell	normal_Lymph_Node-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	NFKBIZ SFMBT2 FGL2 C1QB TNFAIP3	8.35e-05	153	129	5	5424494ea1f09542799045a875cc3eac13de5079
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	HSPG2 OAS1 MOV10L1 GLUD1 BAHCC1	9.15e-05	156	129	5	abea3c183d32062b009a79a2bdf861021989c7ef
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NOB1 LGR5 HEPH LCNL1 ZFP36L2	1.00e-04	159	129	5	330ecbba97d47bc818a5e8d1d84b05d056bd831e
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	LAMA2 PIEZO2 LCNL1 KCNH2 PRDM6	1.00e-04	159	129	5	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-high_Fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NOB1 LGR5 HEPH LCNL1 ZFP36L2	1.00e-04	159	129	5	cbb331eb689d8cea9e1146ba85e0a05d23301c47
ToppCell	368C-Lymphocytic-Plasma_cell-\|368C / Donor, Lineage, Cell class and subclass (all cells)	LMF1 PIM2 TGFBR3L ST6GAL1 SAMD7	1.09e-04	162	129	5	c21a54310b239d999bbc9d8fb5e8fda16e0bc336
ToppCell	368C-Lymphocytic-Plasma_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	LMF1 PIM2 TGFBR3L ST6GAL1 SAMD7	1.09e-04	162	129	5	f945688815229c8386cbcbf46deee7df316fa8d3
ToppCell	normal_Lymph_Node-Myeloid_cells-Monocytes\|Myeloid_cells / Location, Cell class and cell subclass	NFKBIZ FGL2 BST1 IQCJ-SCHIP1 TNFAIP3	1.12e-04	163	129	5	7d7f18e5c99be125e95bc180823430291b770d05
ToppCell	Adult-Immune-B_cell-D231\|Adult / Lineage, Cell type, age group and donor	RGPD2 PIM2 ST6GAL1 PRDM8 CARNS1	1.12e-04	163	129	5	4f5821299b265663c7d0352b28285f56e1988841
ToppCell	droplet-Liver-LIVER-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFKBIZ FGL2 CSF2RB C1QB TNFAIP3	1.16e-04	164	129	5	939d4e3911fce185b986639c815de0a0389f6cfd
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Pleural_Mac\|Myeloid_cells / Location, Cell class and cell subclass	COL11A1 OAS1 RBM20 FGL2 CFAP74	1.16e-04	164	129	5	362c16ed7fb37bf16601fd5e059d3f3e2ed692b4
ToppCell	droplet-Liver-LIVER-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFKBIZ FGL2 CSF2RB C1QB TNFAIP3	1.16e-04	164	129	5	3281f2452cc6b11f3e030a3942002b9457dde6fe
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	FAM234B NOB1 BAP1 SIGLEC11 CARNS1	1.16e-04	164	129	5	d6806deabf5f5c355934387be2baae125ac33fb8
ToppCell	PND01-03-samps-Epithelial-Alveolar_epithelial-AT1\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	COL4A3 UBAP2 MYCBPAP GRHL3 AGRN	1.19e-04	165	129	5	b9b6b7b8cd65ba6948a5dd8b715cc7092e0be637
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Colon_normal_tissue-Colon_normal_tissue-9\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PSD MYOM1 SKIDA1 RBM20 RYR3	1.23e-04	166	129	5	68e6fc7c0040bbe48a93f96ecf28afffdc626845
ToppCell	Ciliated_cells-B-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	TRPV1 MYOM1 MYCBPAP TMCC2 UGT2B4	1.23e-04	166	129	5	4b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCell	droplet-Liver-LIVER\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFKBIZ FGL2 CSF2RB C1QB TNFAIP3	1.26e-04	167	129	5	90125bfdc34b0f9a471cefe6e8a637d5e5e00790
ToppCell	droplet-Liver-LIVER-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFKBIZ FGL2 CSF2RB C1QB TNFAIP3	1.26e-04	167	129	5	4bbc59cc50a68b957125fb11a3b308fe1d542ce9
ToppCell	droplet-Liver-LIVER-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NFKBIZ FGL2 CSF2RB C1QB TNFAIP3	1.26e-04	167	129	5	a038c522e4783cb62802f613d00bd5f3e3797199
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CUX2 COL11A1 CPNE9 LAMA2 IQCJ-SCHIP1	1.26e-04	167	129	5	cb650f74306fa0d9f4bf49890b73065d193b94dc
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 CR1 RYR3 LCNL1 IQCJ-SCHIP1	1.30e-04	168	129	5	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	COVID-19-Myeloid-MoAM5,_CCL3L1\|Myeloid / Condition, Lineage and Cell class	NFKBIZ MOV10L1 ZBTB10 IQCJ-SCHIP1 TNFAIP3	1.30e-04	168	129	5	ea465152ea31391b63c02425beafa9a4f51f6703
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 CR1 RYR3 LCNL1 IQCJ-SCHIP1	1.30e-04	168	129	5	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	356C-Myeloid-Dendritic-cDC_activated\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CHD3 PIEZO2 TMCC2 NGFR ONECUT3	1.33e-04	169	129	5	44d201361eb497222a4972a0e10bac1e05dcfd0a
ToppCell	-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	PIM2 TGFBR3L PIEZO2 LCNL1 ZFP36L2	1.37e-04	170	129	5	601630644f09133ee4c5e64499460b55cf3e80a0
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SHROOM3 CUX2 LAMA2 PRDM8 IQCJ-SCHIP1	1.37e-04	170	129	5	3174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CUX2 SFMBT2 LCNL1 CSF2RB ZFP36L2	1.41e-04	171	129	5	39c8ae139e449217091e1481eb5e2aafb8f69a1c
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MYOM1 RBM20 NGFR CSMD1 PRDM6	1.41e-04	171	129	5	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	COVID-19-Heart-T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CUX2 RYR3 TMCC2 CNTNAP4 CSMD1	1.41e-04	171	129	5	b2e753e811a7639956994609f73efcdb62d04f82
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 RBM20 KCNH2 MOV10L1 RPL3L	1.45e-04	172	129	5	ee8ce9e8c9a6d3ee2be113f77743958005f4b3f0
ToppCell	facs-Heart-Unknown-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYOM1 RBM20 KCNH2 MOV10L1 RPL3L	1.45e-04	172	129	5	bd468a7ea6ec832dcf6a816a1e0c03fa0f176dad
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 CR1 RYR3 LCNL1 IQCJ-SCHIP1	1.45e-04	172	129	5	381ae1c3c07d0a424f43455ec571653b192a946a
ToppCell	Adult-Mesenchymal-airway_smooth_muscle_cell\|Adult / Lineage, Cell type, age group and donor	MYOM1 RBM20 RYR3 SLC6A11 PRDM6	1.49e-04	173	129	5	a5331721bd9f9a66530dd4ffe28cb3a5a8cad8fc
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CUX2 COL11A1 LAMA2 PRDM8 IQCJ-SCHIP1	1.49e-04	173	129	5	9a2d42f8d9cb834856522661d524abb91c4637c5
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SHROOM3 CUX2 COL11A1 LAMA2 IQCJ-SCHIP1	1.49e-04	173	129	5	8ac2e9d39c0f76e674f8bd59d1da246bab4867c8
ToppCell	10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages\|bone_marrow / Manually curated celltypes from each tissue	TTC28 FGL2 GLUD2 C1QB SIGLEC11	1.53e-04	174	129	5	0746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL4A3 CR1 RYR3 LCNL1 IQCJ-SCHIP1	1.53e-04	174	129	5	dbdcdec08f1fc69fcdb5d8a6d78df8ef9c374d89
ToppCell	Healthy_Control-Myeloid-Mast\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	HSPG2 PRDM8 PIEZO2 KCNH2 CARNS1	1.57e-04	175	129	5	ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCell	18-Distal-RBC-RBC\|Distal / Age, Tissue, Lineage and Cell class	PIM2 RYR3 CSF2RB KCNH2 TMCC2	1.57e-04	175	129	5	7130b816e0c02309c161d8e9ad7cb4bc2469e251
ToppCell	Healthy_Control-Myeloid-Mast-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	HSPG2 PRDM8 PIEZO2 KCNH2 CARNS1	1.57e-04	175	129	5	eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCell	10x5'v1-week_17-19-Myeloid_neutrophil-granulo-eo/baso/mast-basophil\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	NFKBIZ CR1 RYR3 CSF2RB TNFAIP3	1.57e-04	175	129	5	ba1befc4e5f0167452f9ceace39377d16136dfa9
ToppCell	facs-Marrow-B-cells-24m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 MUC19 LAMA2 CNTNAP4 CSMD1	1.57e-04	175	129	5	887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell	18-Distal-RBC\|Distal / Age, Tissue, Lineage and Cell class	PIM2 RYR3 CSF2RB KCNH2 TMCC2	1.57e-04	175	129	5	cc476b4244442418b8f21721a82a36209b556b36
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PSD PALB2 TESMIN CAPN7 NGFR	1.61e-04	176	129	5	6b4afd2c9268172063fe5832896bea15e862579e
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL11A1 CHD3 RBM20 RYR3 IL4R	1.61e-04	176	129	5	72a2a01618ce836bc843395d5095e9090759b4a6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SHROOM3 CUX2 CPNE9 PRDM8 IQCJ-SCHIP1	1.61e-04	176	129	5	40993c41c1017b53039a337174fc56632b278609
ToppCell	COVID-19_Severe-CD4+_CTL\|COVID-19_Severe / disease group, cell group and cell class	TGFBR3L LAMA2 ZFP36L2 FBXO31 CARNS1	1.65e-04	177	129	5	34e9455790bae905dd91923792f4109d18b7686e
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-elicited_macrophage-Monocyte-derived_macrophage-Monocyte-derived_macrophage_L.1.2.3.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RGPD2 SFMBT2 FGL2 EEPD1 RAD54L	1.65e-04	177	129	5	f28243b51be104cb3adcde63f03fc2206ed3121e
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	FAM234B TRPV1 RRAGC ZFP36L2 KCNH2 TLE3 TNFAIP3 IL4R BAHCC1	9.24e-07	185	126	9	5585_DN
Drug	valproate	SHROOM3 CUX2 SFMBT2 RYR3 FGL2 SLC6A11 CSF2RB KCNH2 GLUD1 GLUD2 UGT2B4	9.09e-06	381	126	11	CID000003121
Drug	17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A	FAM234B TRPV1 TBC1D30 AHDC1 ZFP36L2 TLE3 AGRN BAHCC1	1.06e-05	189	126	8	5578_DN
Drug	Tolnaftate [2398-96-1]; Down 200; 13uM; MCF7; HT_HG-U133A	HSPG2 LMF1 PIM2 TTC28 CHD3 AHDC1 USP5 ZFP36L2	1.48e-05	198	126	8	4805_DN
Drug	Methoxamine hydrochloride [61-16-5]; Up 200; 16.2uM; MCF7; HT_HG-U133A	TBC1D30 AHDC1 ZFP36L2 BST1 KCNH2 TNFAIP3 AGRN BAHCC1	1.48e-05	198	126	8	2848_UP
Drug	ADP-ribosylcysteine	BST1 GLUD1 GLUD2	2.64e-05	11	126	3	CID003035804
Drug	phenyltriethoxysilane	GLUD1 GLUD2	3.04e-05	2	126	2	CID000013075
Drug	G-3SH	GLUD1 GLUD2	3.04e-05	2	126	2	CID000174237
Drug	iodoacetyldiethylstilbestrol	GLUD1 GLUD2	3.04e-05	2	126	2	CID006455327
Drug	methylmercuric bromide	GLUD1 GLUD2	3.04e-05	2	126	2	CID000068175
Drug	5-methylisophthalate	GLUD1 GLUD2	3.04e-05	2	126	2	CID000068137
Drug	x 1 s	GLUD1 GLUD2	3.04e-05	2	126	2	CID000409694
Disease	atrial fibrillation	HSPG2 CUX2 NACA RBM20 PRDM8 KCNH2 TLE3 RPL3L PRDM6 CRAMP1	4.63e-06	371	126	10	EFO_0000275
Disease	Lymphoma, Follicular, Grade 2	RRAGC KMT2D TNFAIP3	3.33e-05	15	126	3	C1956132
Disease	Lymphoma, Follicular, Grade 3	RRAGC KMT2D TNFAIP3	3.33e-05	15	126	3	C1956131
Disease	Lymphoma, Follicular, Grade 1	RRAGC KMT2D TNFAIP3	3.33e-05	15	126	3	C1956130
Disease	Lymphoma, Large-Cell, Follicular	RRAGC KMT2D TNFAIP3	3.33e-05	15	126	3	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	RRAGC KMT2D TNFAIP3	3.33e-05	15	126	3	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	RRAGC KMT2D TNFAIP3	3.33e-05	15	126	3	C0079758
Disease	Pulmonary alveolar proteinosis, congenital	OAS1 CSF2RB	5.41e-05	3	126	2	C2931035
Disease	fascioliasis (biomarker_via_orthology)	GLUD1 GLUD2	5.41e-05	3	126	2	DOID:885 (biomarker_via_orthology)
Disease	Lymphoma, Follicular	RRAGC KMT2D TNFAIP3	8.22e-05	20	126	3	C0024301
Disease	Sezary Syndrome	TET2 CHD3 KMT2D	2.06e-04	27	126	3	C0036920
Disease	childhood absence epilepsy (biomarker_via_orthology)	GLUD1 GLUD2	2.68e-04	6	126	2	DOID:1825 (biomarker_via_orthology)
Disease	QRS duration	FAT4 COL11A1 NACA ZBTB4 RBM20 DNAJC11 PRDM6	3.03e-04	298	126	7	EFO_0005055
Disease	ascending aortic diameter	TNRC6B PRDM8 PIEZO2 USP15 PRDM6	3.45e-04	140	126	5	EFO_0021787
Disease	vanillylmandelate (VMA) measurement	UGT2B4 CARNS1	3.75e-04	7	126	2	EFO_0800119
Disease	hematocrit	COL4A3 SHROOM3 UBAP2 PITRM1 PIEZO1 TNRC6B CHD3 CR1 PRR12 PRDM8 ZBTB10 BAHCC1 MGRN1	3.98e-04	1011	126	13	EFO_0004348
Disease	diverticular disease	PIEZO1 ZBTB4 TNRC6B KCNH2 UGT2B4 IQCJ-SCHIP1	5.44e-04	236	126	6	EFO_0009959
Disease	Paroxysmal atrial fibrillation	HSPG2 NACA RBM20 KCNH2 RPL3L	5.66e-04	156	126	5	C0235480
Disease	familial atrial fibrillation	HSPG2 NACA RBM20 KCNH2 RPL3L	5.66e-04	156	126	5	C3468561
Disease	Persistent atrial fibrillation	HSPG2 NACA RBM20 KCNH2 RPL3L	5.66e-04	156	126	5	C2585653
Disease	visual epilepsy (biomarker_via_orthology)	SLC6A11 GLUD1 GLUD2 NGFR	6.10e-04	90	126	4	DOID:11832 (biomarker_via_orthology)
Disease	Atrial Fibrillation	HSPG2 NACA RBM20 KCNH2 RPL3L	6.34e-04	160	126	5	C0004238
Disease	gamma-glutamylisoleucine measurement	LAMA2 CARNS1	6.39e-04	9	126	2	EFO_0021139
Disease	albuminuria	COL4A3 SHROOM3 CSMD1 BAHCC1	7.18e-04	94	126	4	EFO_0004285
Disease	Leukemia, Myelocytic, Acute	TET2 PIM2 PALB2 MN1 AGRN	9.01e-04	173	126	5	C0023467
Disease	Microphthalmos	ERCC6 KMT2D	9.70e-04	11	126	2	C0026010
Disease	alcohol and nicotine codependence	RGPD2 CAPN7	1.37e-03	13	126	2	EFO_0004776
Disease	gamma-glutamylleucine measurement	CUX2 CARNS1	1.37e-03	13	126	2	EFO_0021140
Disease	Connective Tissue Diseases	ZNF469 PIEZO2	1.37e-03	13	126	2	C0009782
Disease	corpus callosum posterior volume measurement	ZBTB4 TNRC6B IQCJ-SCHIP1	1.44e-03	52	126	3	EFO_0010298
Disease	myelodysplastic syndrome (implicated_via_orthology)	TET2 BAP1	1.83e-03	15	126	2	DOID:0050908 (implicated_via_orthology)
Disease	glycerate measurement	RYR3 AGRN	1.83e-03	15	126	2	EFO_0021029
Disease	hepatic encephalopathy (biomarker_via_orthology)	GLUD1 GLUD2	1.83e-03	15	126	2	DOID:13413 (biomarker_via_orthology)
Disease	Spondyloepiphyseal Dysplasia	HSPG2 COL11A1	2.09e-03	16	126	2	C0038015
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	HSPG2 COL11A1	2.09e-03	16	126	2	C3541456
Disease	Schwartz-Jampel Syndrome, Type 1	HSPG2 COL11A1	2.09e-03	16	126	2	C4551479
Disease	Schwartz-Jampel Syndrome	HSPG2 COL11A1	2.09e-03	16	126	2	C0036391
Disease	Melnick-Needles Syndrome	HSPG2 COL11A1	2.09e-03	16	126	2	C0025237
Disease	Malignant neoplasm of breast	COL11A1 ERCC6 LAMA2 RFC4 CIC PALB2 BAP1 KMT2D TLE3 C1QB SPOCD1 RAD54L	2.21e-03	1074	126	12	C0006142
Disease	psoriasis vulgaris	NFKBIZ TNFAIP3 GRHL3	2.28e-03	61	126	3	EFO_1001494
Disease	disease progression measurement	RYR3 UGT2B4 IQCJ-SCHIP1	2.28e-03	61	126	3	EFO_0008336
Disease	Van Buchem disease	HSPG2 COL11A1	2.36e-03	17	126	2	C0432272
Disease	MHPG measurement, 5-HIAA measurement	COL4A3 PIEZO2	2.36e-03	17	126	2	EFO_0005132, EFO_0005133
Disease	bitter alcoholic beverage consumption measurement	TNRC6B CIC CSMD1 BAHCC1	2.58e-03	133	126	4	EFO_0010092
Disease	Global developmental delay	CHD3 PRR12 SLC25A12 MN1	2.58e-03	133	126	4	C0557874
Disease	peritonsillar abscess	TET2 NFKBIZ	2.65e-03	18	126	2	EFO_0007429
Disease	p-tau:beta-amyloid 1-42 ratio measurement	TTC28 PRDM6	2.95e-03	19	126	2	EFO_0007709
Disease	Osteochondrodysplasias	HSPG2 COL11A1	2.95e-03	19	126	2	C0029422
Disease	Dyschondroplasias	HSPG2 COL11A1	2.95e-03	19	126	2	C0013366
Disease	Hereditary Non-Polyposis Colon Cancer Type 2	NFKBIZ PALB2	2.95e-03	19	126	2	C1333991
Disease	Colorectal cancer, hereditary nonpolyposis, type 1	NFKBIZ PALB2	2.95e-03	19	126	2	C2936783
Disease	lung non-small cell carcinoma (is_implicated_in)	TET2 ERCC6 KMT2D FOXL2	3.03e-03	139	126	4	DOID:3908 (is_implicated_in)
Disease	Bladder Neoplasm	TRPV1 LAMA2 BAP1 KMT2D	3.11e-03	140	126	4	C0005695
Disease	Intellectual Disability	CUX2 PITRM1 CHD3 CIC PRR12 SCN8A MN1	3.15e-03	447	126	7	C3714756
Disease	Malignant neoplasm of urinary bladder	TRPV1 LAMA2 BAP1 KMT2D	3.19e-03	141	126	4	C0005684
Disease	Multiple Epiphyseal Dysplasia	HSPG2 COL11A1	3.27e-03	20	126	2	C0026760
Disease	breast cancer, COVID-19	CUX2 TTC28	3.95e-03	22	126	2	MONDO_0007254, MONDO_0100096
Disease	glomerular filtration rate, renal transplant outcome measurement, donor genotype effect measurement	FAM234B CSMD1	3.95e-03	22	126	2	EFO_0005199, EFO_0005208, EFO_0007892
Disease	esophagus squamous cell carcinoma (is_marker_for)	TET2 KMT2D TNFAIP3	3.95e-03	74	126	3	DOID:3748 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
LNGSEPTGAYPIKGF	BST1	191	Q10588
PGLPKSGLDKSGYFE	BAHCC1	481	Q9P281
SPVELPFGGYKKSGF	ALDH9A1	451	P49189
GKSGTVLSPGFPDFY	CSMD1	936	Q96PZ7
SGLPGESYGSEKGAP	COL4A3	276	Q01955
FSGKGDITKPGYDPC	FBXW10	241	Q5XX13
ARDGGFPPFSSYEKL	FAT4	2641	Q6V0I7
PALPKAYGTGFVGCL	AGRN	2026	O00468
SGAGPAGPYAKESGI	CHIA	286	Q9BZP6
LDYEISFGGIPAPGK	CNTNAP4	306	Q9C0A0
FTYKPPGLLRGGDAS	CARNS1	111	A5YM72
AFYVGGSKASPDPDL	DPH2	216	Q9BQC3
GFSPESKGYAIGNAP	BAP1	121	Q92560
SALGYKDLGPGSPQT	CAPN8	56	A6NHC0
SPPYEGKVGTGLLAD	AHDC1	1476	Q5TGY3
AGGLLVFPPAFYGAK	CUX2	501	O14529
DLPKAGTLPTSGYGN	DLX4	206	Q92988
LAGPSPYLGRFKVGS	EEPD1	381	Q7L9B9
SGDGTDYELKPLPKG	ERCC6	396	Q03468
IGKTGPAPATAGFYE	RBM20	216	Q5T481
YPDYGAIPKAGLSSG	HSPG2	3801	P98160
GALDLFPPGYSSKAL	RAD54L	476	Q92698
SGDGTDYELKPLPKG	ERCC6	396	P0DP91
ASKAGLPGFYDPCVG	DNAJC11	506	Q9NVH1
TPLGNGDLALKFGYP	LCNL1	26	Q6ZST4
GDLALKFGYPTPHGG	LCNL1	31	Q6ZST4
GLRYSLPTPKGGKYA	NOB1	321	Q9ULX3
YSGKRKGPDSLSDGP	NFKBIZ	161	Q9BYH8
PGLAEGRPSLYAGDK	MOV10L1	571	Q9BXT6
GEKFDTPHPEGYLFG	MGRN1	41	O60291
PYNSSGLGGPSIKDK	KCNH2	596	Q12809
PFRYGGDGSKGPTIS	COL11A1	496	P12107
KFFYAGTPPAGLAAD	ENDOD1	36	O94919
PDDLIKPGLFKGTYG	FBXO31	296	Q5XUX0
DRTKPFFSLGLGAPG	MUC19	101	Q7Z5P9
GYPSEPLGGLEQKAA	FAM234B	81	A2RU67
KGLAGPAASYGPYTR	FOXL2	246	P58012
PPGAGKSTFIEYFGK	MMAA	151	Q8IVH4
DKCLPGFYGEPTKGT	LAMA2	786	P24043
PAFDALGQLTGGYKP	OAS1	151	P00973
DPGGSAFLKVDPAYL	PRDM6	6	Q9NQX0
LGTTPAFGPQGSYEK	PALB2	731	Q86YC2
YPLRGSSIFGLAPGK	ALPG	386	P10696
SVSFGLFYKPSPDAG	CSF2RB	271	P32927
GPPGEAGYKAFSSLL	IL4R	596	P24394
GQFYPVTLRTPAGGK	GRHL3	256	Q8TE85
DPGPHGFLRKSSGDY	CAPN7	751	Q9Y6W3
TGTPFGDIPYGKEIS	CR1	1786	P17927
ESPKLPSGAYEGGAL	CHD3	1041	Q12873
GSILGFPKAKPYEGS	GLUD1	356	P00367
SDKLFPAYGFGAKLP	CPNE9	346	Q8IYJ1
YGEGVPLSPAKLNGS	CRAMP1	1111	Q96RY5
APGPKGESGDYKATQ	C1QB	106	P02746
GGKLDTFCGSPPYAA	MARK3	206	P27448
PGVSEAHPGGYKSSF	FGL2	411	Q14314
YFKGRGLDLGTFPNP	C2orf66	66	Q6UXQ4
KRDEGGTGKYPPASL	AHCTF1	741	Q8WYP5
AKPPGAAEEASGKYG	FIGNL2	311	A6NMB9
GGLGTTFKFLPASEP	CFAP74	646	Q9C0B2
GSILGFPKAKPYEGS	GLUD2	356	P49448
SPGSSGVPYANAKGI	FAM168B	6	A1KXE4
AAVPLLGGSKYGASP	LGR5	696	O75473
AAYGPPGHLAGDKLL	ONECUT3	226	O60422
KYSAAPDSGGAPGVS	MN1	961	Q10571
TGGLEGSHYLPPTKF	TESMIN	421	Q9Y4I5
FYGPPGTGKTSTILA	RFC4	76	P35249
PLAGSYGAADSFPKD	RRAGC	11	Q9HB90
TLPGAGAGIKFYLYP	SLC6A6	266	P31641
SSGPAGPYLLSKKGA	PLEKHN1	511	Q494U1
KFAFPVPYGLGGVAD	SOX21	91	Q9Y651
EFFYGSLDPPSSGAK	PSD	241	A5PKW4
GPGGALGSPKSNALY	TMCC2	496	O75069
PKGLAGLGIPFLYGS	SAMD7	116	Q7Z3H4
PGGLKGSARFLSFGP	TGFBR3L	26	H3BV60
KTSLFPYALQGPAGF	NKX6-2	26	Q9C056
AKSITPLGGFPHYGE	RPL3L	311	Q92901
QGSAPSPGKKLRGFY	RGPD2	16	P0DJD1
FDYITEKGPLGEGPS	PIM2	126	Q9P1W9
FVGFSSKPSPIYGGL	MT-ND6	16	P03923
GGGLPKQSPFLYATA	PRDM8	566	Q9NQV8
SEGSLYPDGSSGPLK	HEPH	136	Q9BQS7
GPNSPFYKALIESGL	PITRM1	356	Q5JRX3
LGSPKPEDGEYKFGA	SKIDA1	761	Q1XH10
FGLVKDPCYLAGPGS	SHROOM3	1261	Q8TF72
YKGPGPGIKFSAEAL	ST6GAL1	126	P15907
KLALGSFFDDGPGIY	IQCJ-SCHIP1	341	B3KU38
KGAFGPTPLYRAAFG	IQANK1	221	A8MXQ7
GSPGAPGKYLSSVLA	PRR12	581	Q9ULL5
KSPYLGLGPGHSYVS	PRORP	16	O15091
AGYPKPIFKGFGGLT	PRG4	1226	Q92954
YIDFGGLKPAGSEPT	SLC25A12	606	O75746
PVAFGKGYGSAPSSS	CIC	521	Q96RK0
LLFGPPGTGKSYLAK	VPS4B	171	O75351
PYPGDVTKFGRGDSA	UBAP2	861	Q5T6F2
PGKGPEFLFTLYSAG	TRAV20	61	A0A0B4J274
GSNFAPLKVGGIYLP	TNFAIP3	221	P21580
FYGPPGCGKTLLAKA	VCP	516	P55072
KGRPGFYFGELPLSL	TRPV1	241	Q8NER1
PGYAIEKHSGGLLFP	UGT2B4	176	P06133
GDGGLYSSLPPAKRE	NGFR	331	P08138
ESKGGGSHPLLVPYD	RYR3	2756	Q15413
GTEKFGYLPATGDGP	SPOCD1	281	Q6ZMY3
GVSLTPPKGYSGQDF	SFMBT2	366	Q5VUG0
KVSPPSLGFLAGYGI	PIEZO2	2656	Q9H5I5
YPGPIDNSGLLKDGD	USP15	61	Q9Y4E8
SPGLLASEKTPNGGY	ZBTB4	391	Q9P1Z0
KGAGALPFLPGVFGY	ZBTB4	956	Q9P1Z0
TKPLDYSGPGDSFDG	MYCBPAP	121	Q8TBZ2
ILSGGTALKPPYSAF	PRRC2B	2011	Q5JSZ5
AESGPGLAFIAYPKA	SLC6A11	371	P48066
AGKSLPFIYGDIPQG	SCN8A	61	Q9UQD0
TANKESGGGYEPPLT	TBC1D30	411	Q9Y2I9
PSDFGGTLPKYDGKA	RLBP1	286	P12271
SSLASIPGGKPAYSF	TLE3	436	Q04726
AKAFPFPADGLGAEG	ZNF469	666	Q96JG9
LPSGNGYKFLSPGRF	TTC28	2461	Q96AY4
EKSYALGGARGPQPS	ZSCAN18	466	Q8TBC5
GPSNDFKYGLIPGTS	ZBTB10	666	Q96DT7
IPGTSNDFKYGLIPG	ZBTB10	676	Q96DT7
KVSPPSLGFLAGYGI	PIEZO1	2426	Q92508
APILEKPKGSSGGYG	WIPF2	61	Q8TF74
FPGESGLAPGSYKKA	UNK	401	Q9C0B0
GLAPGSYKKAPGFER	UNK	406	Q9C0B0
EKDEGPFYTHLGAGP	TET2	1141	Q6N021
AAGGPTSYGTLKEPS	ZFP36L2	91	P47974
PVLGAGSLNKDPSYS	SIGLEC11	21	Q96RL6
LVTPDEPKGSLGFYG	USP5	621	P45974
DLQTKGPIPGYGSGF	TNRC6B	1361	Q9UPQ9
RGISSGYPFLKPAGI	ZNF662	46	Q6ZS27
FGPPGTGKSYLAKAV	VPS4A	166	Q9UN37
LSPLGELEYPFGAKG	KMT2D	951	O14686
ATLGFLFPSGPGSLK	LMF1	326	Q96S06
YAGPDSAGPLLKSSL	NACA	626	E9PAV3
GPATAPYSLETLKGG	SLC4A1AP	161	Q9BWU0
KQPAVDGGSPILGYF	MYOM1	531	P52179