Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	zinc ion binding	TUT7 TRIM31 NSD1 ZMYM2 PEX12 ZNF385A ERI2 SKI AR TRIM10 NR1I2 RNF2 RNF5 TRIM17 SUV39H1 NFXL1 RABGEF1 ALB TNFAIP3	2.40e-07	891	107	19	GO:0008270
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	MKRN3 MKRN4P MKRN1 TRIM31 PEX12 BIRC3 TRIM10 RNF2 RNF5 LMO7 TRIM17 RABGEF1 TNFAIP3	1.50e-06	473	107	13	GO:0004842
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	MKRN3 MKRN4P MKRN1 TRIM31 PEX12 BIRC3 TRIM10 RNF2 RNF5 LMO7 TRIM17 RABGEF1 TNFAIP3	3.58e-06	512	107	13	GO:0019787
GeneOntologyMolecularFunction	transition metal ion binding	TUT7 TRIM31 NSD1 ZMYM2 PEX12 ZNF385A ERI2 SKI AR TRIM10 NR1I2 RNF2 RNF5 TRIM17 SUV39H1 GLUL NFXL1 RABGEF1 ALB TNFAIP3	4.47e-06	1189	107	20	GO:0046914
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	MKRN3 MKRN4P MKRN1 TRIM31 PEX12 BIRC3 TRIM10 RNF2 RNF5 TRIM17 RABGEF1	5.07e-06	372	107	11	GO:0061630
GeneOntologyMolecularFunction	aminoacyltransferase activity	MKRN3 MKRN4P MKRN1 TRIM31 PEX12 BIRC3 TRIM10 RNF2 RNF5 LMO7 TRIM17 RABGEF1 TNFAIP3	5.42e-06	532	107	13	GO:0016755
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	MKRN3 MKRN4P MKRN1 TRIM31 PEX12 BIRC3 TRIM10 RNF2 RNF5 TRIM17 RABGEF1	9.60e-06	398	107	11	GO:0061659
GeneOntologyMolecularFunction	PLC activating G protein-coupled glutamate receptor activity	GRM1 GRM5	2.84e-05	2	107	2	GO:0001639
GeneOntologyMolecularFunction	acyltransferase activity	MKRN3 MKRN4P MKRN1 TRIM31 PEX12 BIRC3 TRIM10 RNF2 RNF5 LMO7 TRIM17 GLUL RABGEF1 TNFAIP3	6.72e-05	775	107	14	GO:0016746
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL6A5 FBLN1 SRPX2 PCOLCE2 LTBP1 BMPER MUC3A	6.92e-05	188	107	7	GO:0005201
GeneOntologyMolecularFunction	NuRD complex binding	PWWP2A PWWP2B	8.50e-05	3	107	2	GO:0120325
GeneOntologyMolecularFunction	neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration	GRM1 GRM5	1.69e-04	4	107	2	GO:0099583
GeneOntologyMolecularFunction	G protein-coupled receptor activity involved in regulation of postsynaptic membrane potential	GRM1 GRM5	2.81e-04	5	107	2	GO:0099530
GeneOntologyMolecularFunction	chromatin binding	MKRN4P MKRN1 NSD1 SKI AR CDC45 PWWP2A PRDM11 RNF2 SUV39H1 SUZ12 H2AL3	6.00e-04	739	107	12	GO:0003682
GeneOntologyMolecularFunction	G protein-coupled glutamate receptor activity	GRM1 GRM5	9.99e-04	9	107	2	GO:0098988
GeneOntologyMolecularFunction	adenylate cyclase inhibiting G protein-coupled glutamate receptor activity	GRM1 GRM5	9.99e-04	9	107	2	GO:0001640
GeneOntologyMolecularFunction	transforming growth factor beta receptor activity	BMPR1A LTBP1	2.13e-03	13	107	2	GO:0005024
GeneOntologyCellularComponent	collagen-containing extracellular matrix	COL6A5 ITLN2 MDK FBLN1 SRPX2 PCSK6 PCOLCE2 LTBP1 ALB BMPER	3.12e-04	530	104	10	GO:0062023
GeneOntologyCellularComponent	extracellular matrix	ADAMTS19 COL6A5 ITLN2 MDK FBLN1 SRPX2 PCSK6 PCOLCE2 LTBP1 ALB BMPER	4.24e-04	656	104	11	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTS19 COL6A5 ITLN2 MDK FBLN1 SRPX2 PCSK6 PCOLCE2 LTBP1 ALB BMPER	4.35e-04	658	104	11	GO:0030312
GeneOntologyCellularComponent	sex chromatin	RNF2 SUZ12	5.07e-04	7	104	2	GO:0001739
Domain	Znf_RING	MKRN3 MKRN4P MKRN1 DEF8 TRIM31 NSD1 PEX12 BIRC3 TRIM10 RNF2 RNF5 TRIM17 NFXL1	3.63e-08	326	105	13	IPR001841
Domain	RING	MKRN3 MKRN4P MKRN1 DEF8 TRIM31 NSD1 PEX12 BIRC3 TRIM10 RNF2 RNF5 TRIM17	1.46e-07	305	105	12	SM00184
Domain	ZF_RING_1	MKRN3 MKRN4P MKRN1 TRIM31 PEX12 BIRC3 TRIM10 RNF2 RNF5 TRIM17 NFXL1	7.40e-07	291	105	11	PS00518
Domain	ZF_RING_2	MKRN3 MKRN4P MKRN1 TRIM31 PEX12 BIRC3 TRIM10 RNF2 RNF5 TRIM17 NFXL1	9.35e-07	298	105	11	PS50089
Domain	Sushi	SELE CFH SRPX2 C2 C6	1.07e-05	52	105	5	PF00084
Domain	CCP	SELE CFH SRPX2 C2 C6	1.30e-05	54	105	5	SM00032
Domain	SUSHI	SELE CFH SRPX2 C2 C6	1.55e-05	56	105	5	PS50923
Domain	Sushi_SCR_CCP_dom	SELE CFH SRPX2 C2 C6	1.69e-05	57	105	5	IPR000436
Domain	GPCR_3_mtglu_rcpt_5	GRM1 GRM5	3.13e-05	2	105	2	IPR000202
Domain	GluR_Homer-bdg	GRM1 GRM5	3.13e-05	2	105	2	PF10606
Domain	MKRN1_C	MKRN3 MKRN1	3.13e-05	2	105	2	PF15815
Domain	Metabotropic_Glu_rcpt_Homer-bd	GRM1 GRM5	3.13e-05	2	105	2	IPR019588
Domain	MKRN1_C	MKRN3 MKRN1	3.13e-05	2	105	2	IPR031644
Domain	GPCR_3_mtglu_rcpt_1	GRM1 GRM5	3.13e-05	2	105	2	IPR001256
Domain	GluR_Homer-bdg	GRM1 GRM5	3.13e-05	2	105	2	SM01229
Domain	zf-C3HC4	MKRN3 MKRN4P MKRN1 TRIM31 TRIM10 RNF2 RNF5 TRIM17	3.76e-05	223	105	8	PF00097
Domain	Znf_RING_CS	MKRN3 MKRN1 TRIM31 TRIM10 RNF2 RNF5 TRIM17	3.77e-05	163	105	7	IPR017907
Domain	Znf_C3HC4_RING-type	MKRN3 MKRN1 TRIM31 TRIM10 RNF2 RNF5 TRIM17	5.30e-05	172	105	7	IPR018957
Domain	Znf_RING/FYVE/PHD	MKRN3 MKRN1 SYTL2 TRIM31 NSD1 PEX12 BIRC3 TRIM10 RNF2 RNF5 TRIM17	5.47e-05	459	105	11	IPR013083
Domain	EGF-like_dom	SELE STAB2 TMEFF2 FBLN1 PCSK6 LTBP1 C6 MUC3A	8.17e-05	249	105	8	IPR000742
Domain	Fas_rcpt	TNFRSF14 LTBR	9.36e-05	3	105	2	IPR008063
Domain	PWWP	NSD1 PWWP2A PWWP2B	1.84e-04	20	105	3	SM00293
Domain	-	MKRN3 MKRN1 SYTL2 TRIM31 NSD1 PEX12 TRIM10 RNF2 RNF5 TRIM17	2.20e-04	449	105	10	3.30.40.10
Domain	PWWP	NSD1 PWWP2A PWWP2B	2.82e-04	23	105	3	PF00855
Domain	PWWP_dom	NSD1 PWWP2A PWWP2B	2.82e-04	23	105	3	IPR000313
Domain	DUF3504	ZMYM2 KIAA1958	3.10e-04	5	105	2	IPR021893
Domain	DUF3504	ZMYM2 KIAA1958	3.10e-04	5	105	2	PF12012
Domain	PWWP	NSD1 PWWP2A PWWP2B	3.21e-04	24	105	3	PS50812
Domain	EGF_3	SELE STAB2 TMEFF2 FBLN1 LTBP1 C6 MUC3A	3.65e-04	235	105	7	PS50026
Domain	EGF	SELE STAB2 TMEFF2 FBLN1 PCSK6 LTBP1 MUC3A	3.65e-04	235	105	7	SM00181
Domain	EGF_1	SELE STAB2 TMEFF2 FBLN1 LTBP1 C6 MUC3A	5.95e-04	255	105	7	PS00022
Domain	Znf_A20	RABGEF1 TNFAIP3	6.45e-04	7	105	2	IPR002653
Domain	ZF_A20	RABGEF1 TNFAIP3	6.45e-04	7	105	2	PS51036
Domain	zf-A20	RABGEF1 TNFAIP3	6.45e-04	7	105	2	PF01754
Domain	ZnF_A20	RABGEF1 TNFAIP3	6.45e-04	7	105	2	SM00259
Domain	EGF-like_CS	SELE STAB2 TMEFF2 FBLN1 LTBP1 C6 MUC3A	6.82e-04	261	105	7	IPR013032
Domain	EGF_2	SELE STAB2 TMEFF2 FBLN1 LTBP1 C6 MUC3A	7.46e-04	265	105	7	PS01186
Domain	VPS9	ANKRD27 RABGEF1	8.57e-04	8	105	2	SM00167
Domain	GPCR_3_mtglu_rcpt	GRM1 GRM5	8.57e-04	8	105	2	IPR000162
Domain	ZU5	ANK1 ANK2	1.10e-03	9	105	2	SM00218
Domain	Ank_2	ANK1 ANK2 DGKZ ANKRD27 SNCAIP RAI14	1.36e-03	215	105	6	PF12796
Domain	ZU5	ANK1 ANK2	1.37e-03	10	105	2	PS51145
Domain	Ank_3	ANK1 ANKRD27	1.37e-03	10	105	2	PF13606
Domain	VPS9	ANKRD27 RABGEF1	1.37e-03	10	105	2	PS51205
Domain	VPS9	ANKRD27 RABGEF1	1.37e-03	10	105	2	PF02204
Domain	VPS9	ANKRD27 RABGEF1	1.37e-03	10	105	2	IPR003123
Domain	SET	NSD1 PRDM11 SUV39H1	1.58e-03	41	105	3	PF00856
Domain	Ank	ANK1 ANK2 DGKZ ANKRD27 SNCAIP RAI14	1.83e-03	228	105	6	PF00023
Domain	Growth_fac_rcpt_	STAB2 ESM1 FBLN1 PCSK6 LTBP1	1.88e-03	156	105	5	IPR009030
Domain	ZU5	ANK1 ANK2	1.99e-03	12	105	2	PF00791
Domain	ZU5_dom	ANK1 ANK2	1.99e-03	12	105	2	IPR000906
Domain	SET	NSD1 PRDM11 SUV39H1	2.20e-03	46	105	3	SM00317
Domain	NCD3G	GRM1 GRM5	2.35e-03	13	105	2	PF07562
Domain	GPCR_3_9-Cys_dom	GRM1 GRM5	2.35e-03	13	105	2	IPR011500
Domain	ZnF_C3H1	MKRN3 MKRN4P MKRN1	2.49e-03	48	105	3	SM00356
Domain	zf-CCCH	MKRN3 MKRN4P MKRN1	2.64e-03	49	105	3	PF00642
Domain	PLAC	ADAMTS19 PCSK6	2.73e-03	14	105	2	PF08686
Domain	GPCR_3_CS	GRM1 GRM5	2.73e-03	14	105	2	IPR017979
Domain	CNH	CDC42BPG MAP4K2	2.73e-03	14	105	2	SM00036
Domain	-	ANK1 ANK2 DGKZ ANKRD27 SNCAIP RAI14	2.78e-03	248	105	6	1.25.40.20
Domain	SET_dom	NSD1 PRDM11 SUV39H1	2.79e-03	50	105	3	IPR001214
Domain	SET	NSD1 PRDM11 SUV39H1	2.79e-03	50	105	3	PS50280
Domain	ANK	ANK1 ANK2 DGKZ ANKRD27 SNCAIP RAI14	2.95e-03	251	105	6	SM00248
Domain	ANK_REPEAT	ANK1 ANK2 DGKZ ANKRD27 SNCAIP RAI14	3.07e-03	253	105	6	PS50088
Domain	Ankyrin_rpt-contain_dom	ANK1 ANK2 DGKZ ANKRD27 SNCAIP RAI14	3.13e-03	254	105	6	IPR020683
Domain	ANK_REP_REGION	ANK1 ANK2 DGKZ ANKRD27 SNCAIP RAI14	3.13e-03	254	105	6	PS50297
Domain	CNH	CDC42BPG MAP4K2	3.13e-03	15	105	2	PF00780
Domain	CNH	CDC42BPG MAP4K2	3.13e-03	15	105	2	PS50219
Domain	CNH_dom	CDC42BPG MAP4K2	3.13e-03	15	105	2	IPR001180
Domain	Post-SET_dom	NSD1 SUV39H1	3.57e-03	16	105	2	IPR003616
Domain	PostSET	NSD1 SUV39H1	3.57e-03	16	105	2	SM00508
Domain	POST_SET	NSD1 SUV39H1	3.57e-03	16	105	2	PS50868
Domain	Ankyrin_rpt	ANK1 ANK2 DGKZ ANKRD27 SNCAIP RAI14	3.64e-03	262	105	6	IPR002110
Domain	C1_1	CDC42BPG DEF8 DGKZ	4.05e-03	57	105	3	PF00130
Domain	Znf_CCCH	MKRN3 MKRN4P MKRN1	4.26e-03	58	105	3	IPR000571
Domain	PLAC	ADAMTS19 PCSK6	5.03e-03	19	105	2	PS50900
Domain	PLAC	ADAMTS19 PCSK6	5.03e-03	19	105	2	IPR010909
Domain	TSP_1	ADAMTS19 THSD1 C6	5.37e-03	63	105	3	PF00090
Domain	EGF	SELE STAB2 TMEFF2 LTBP1	5.59e-03	126	105	4	PF00008
Domain	ZF_DAG_PE_1	CDC42BPG DEF8 DGKZ	5.61e-03	64	105	3	PS00479
Domain	ZF_DAG_PE_2	CDC42BPG DEF8 DGKZ	5.61e-03	64	105	3	PS50081
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL6A5 ITLN2 FBLN1 SRPX2 PCOLCE2 LTBP1 BMPER	9.04e-07	167	107	7	22159717
Pubmed	Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15.	TRIM31 RNF2 RNF5 TRIM17 TNFAIP3	1.53e-06	63	107	5	23105109
Pubmed	Identification of potential nuclear reprogramming and differentiation factors by a novel selection method for cloning chromatin-binding proteins.	MKRN4P MKRN1 NSD1	1.57e-06	8	107	3	15522233
Pubmed	A protein interaction network for pluripotency of embryonic stem cells.	ZMYM2 RYBP RNF2 RAI14	7.85e-06	41	107	4	17093407
Pubmed	Cyclic ADP ribose-dependent Ca2+ release by group I metabotropic glutamate receptors in acutely dissociated rat hippocampal neurons.	GRM1 GRM5	9.38e-06	2	107	2	22028929
Pubmed	Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP.	GRM1 GRM5	9.38e-06	2	107	2	9185557
Pubmed	Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation.	MKRN4P MKRN1	9.38e-06	2	107	2	30143610
Pubmed	Herpesvirus entry mediator (HVEM) attenuates signals mediated by the lymphotoxin β receptor (LTβR) in human cells stimulated by the shared ligand LIGHT.	TNFRSF14 LTBR	9.38e-06	2	107	2	24980868
Pubmed	mGluR₁,5 activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: implication for anxiety-like behavior in DBA/2 mice.	GRM1 GRM5	9.38e-06	2	107	2	22681774
Pubmed	mGluR1,5 activation protects cortical astrocytes and GABAergic neurons from ischemia-induced impairment.	GRM1 GRM5	9.38e-06	2	107	2	23280324
Pubmed	Metabotropic glutamate receptors in the main olfactory bulb drive granule cell-mediated inhibition.	GRM1 GRM5	9.38e-06	2	107	2	17093122
Pubmed	In-vivo genetic ablation of metabotropic glutamate receptor type 5 slows down disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis.	GRM1 GRM5	9.38e-06	2	107	2	31102766
Pubmed	Origin and evolution of processed pseudogenes that stabilize functional Makorin1 mRNAs in mice, primates and other mammals.	MKRN4P MKRN1	9.38e-06	2	107	2	16415359
Pubmed	Corticostriatal LTP requires combined mGluR1 and mGluR5 activation.	GRM1 GRM5	9.38e-06	2	107	2	12559117
Pubmed	Stimulating lymphotoxin beta receptor on the dendritic cells is critical for their homeostasis and expansion.	TNFRSF14 LTBR	9.38e-06	2	107	2	16272360
Pubmed	Involvement of group I metabotropic glutamate receptors and glutamate transporters in the slow excitatory synaptic transmission in the spinal cord dorsal horn.	GRM1 GRM5	9.38e-06	2	107	2	18554818
Pubmed	Identification of a new androgen receptor (AR) co-regulator BUD31 and related peptides to suppress wild-type and mutated AR-mediated prostate cancer growth via peptide screening and X-ray structure analysis.	AR BUD31	9.38e-06	2	107	2	25091737
Pubmed	The transcriptional repressor RYBP is a natively unfolded protein which folds upon binding to DNA.	RYBP RNF2	9.38e-06	2	107	2	19170609
Pubmed	Fibulin-1c regulates transforming growth factor-β activation in pulmonary tissue fibrosis.	FBLN1 LTBP1	9.38e-06	2	107	2	31343988
Pubmed	Group 1 metabotropic glutamate receptors 1 and 5 form a protein complex in mouse hippocampus and cortex.	GRM1 GRM5	9.38e-06	2	107	2	27392515
Pubmed	Differences in SUV39H1 and androgen receptor distribution in adenomyomatous hyperplasia and prostatic adenocarcinoma.	AR SUV39H1	9.38e-06	2	107	2	36149194
Pubmed	Genetic inactivation of mGlu5 receptor improves motor coordination in the Grm1crv4 mouse model of SCAR13 ataxia.	GRM1 GRM5	9.38e-06	2	107	2	28982591
Pubmed	An expressed pseudogene regulates the messenger-RNA stability of its homologous coding gene.	MKRN4P MKRN1	9.38e-06	2	107	2	12721631
Pubmed	Selective induction of metabotropic glutamate receptor 1- and metabotropic glutamate receptor 5-dependent chemical long-term potentiation at oriens/alveus interneuron synapses of mouse hippocampus.	GRM1 GRM5	9.38e-06	2	107	2	18035501
Pubmed	Determination of group I metabotropic glutamate receptor subtypes involved in the frequency of epileptiform activity in vitro using mGluR1 and mGluR5 mutant mice.	GRM1 GRM5	9.38e-06	2	107	2	12623213
Pubmed	Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation.	GRM1 GRM5	9.38e-06	2	107	2	15184389
Pubmed	Distinct fetal Ank-1 and Ank-2 related proteins and mRNAs in normal and nb/nb mice.	ANK1 ANK2	9.38e-06	2	107	2	8471772
Pubmed	Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.	GRM1 GRM5	9.38e-06	2	107	2	11591458
Pubmed	Symmetric signal transduction and negative allosteric modulation of heterodimeric mGlu1/5 receptors.	GRM1 GRM5	9.38e-06	2	107	2	33279506
Pubmed	Identification of Makorin 1 as a novel SEREX antigen of esophageal squamous cell carcinoma.	MKRN4P MKRN1	9.38e-06	2	107	2	19604354
Pubmed	The putatively functional Mkrn1-p1 pseudogene is neither expressed nor imprinted, nor does it regulate its source gene in trans.	MKRN4P MKRN1	9.38e-06	2	107	2	16882727
Pubmed	Role of A20 in cIAP-2 protection against tumor necrosis factor α (TNF-α)-mediated apoptosis in endothelial cells.	BIRC3 TNFAIP3	9.38e-06	2	107	2	24595242
Pubmed	mGluR5 Is Substitutable for mGluR1 in Cerebellar Purkinje Cells for Motor Coordination, Developmental Synapse Elimination, and Motor Learning.	GRM1 GRM5	9.38e-06	2	107	2	35805089
Pubmed	Enhanced Function and Overexpression of Metabotropic Glutamate Receptors 1 and 5 in the Spinal Cord of the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis during Disease Progression.	GRM1 GRM5	9.38e-06	2	107	2	31540330
Pubmed	Differential distribution of group I metabotropic glutamate receptors in developing human cortex.	GRM1 GRM5	9.38e-06	2	107	2	20149785
Pubmed	Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.	MKRN3 TRIM31 BIRC3 RNF2 TRIM17	1.90e-05	105	107	5	22493164
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	TMA16 ZNF280C NSD1 ZMYM2 PWWP2A RNF2 SUV39H1 BUD31 SUZ12 ZBTB11	1.90e-05	608	107	10	36089195
Pubmed	Highly oxidized albumin is cleared by liver sinusoidal endothelial cells via the receptors stabilin-1 and -2.	STAB2 ALB	2.81e-05	3	107	2	37926735
Pubmed	Calcineurin inhibitor protein (CAIN) attenuates Group I metabotropic glutamate receptor endocytosis and signaling.	GRM1 GRM5	2.81e-05	3	107	2	19717561
Pubmed	Immune evasion of the human pathogenic yeast Candida albicans: Pra1 is a Factor H, FHL-1 and plasminogen binding surface protein.	CFH FHL1	2.81e-05	3	107	2	19850343
Pubmed	Role of synaptic metabotropic glutamate receptors in epileptiform discharges in hippocampal slices.	GRM1 GRM5	2.81e-05	3	107	2	12364493
Pubmed	Gas1 is induced during and participates in excitotoxic neuronal death.	GAS1 BIRC3	2.81e-05	3	107	2	11906213
Pubmed	Identification and characterization of a novel androgen receptor coregulator ARA267-alpha in prostate cancer cells.	NSD1 AR	2.81e-05	3	107	2	11509567
Pubmed	Asparagine and aspartate hydroxylation of the cytoskeletal ankyrin family is catalyzed by factor-inhibiting hypoxia-inducible factor.	ANK1 ANK2	2.81e-05	3	107	2	21177872
Pubmed	RYBP inhibits esophageal squamous cell carcinoma proliferation through downregulating CDC6 and CDC45 in G1-S phase transition process.	CDC45 RYBP	2.81e-05	3	107	2	32209426
Pubmed	Attenuation of graft arterial disease by manipulation of the LIGHT pathway.	TNFRSF14 LTBR	2.81e-05	3	107	2	15178556
Pubmed	Suppression of PPARγ through MKRN1-mediated ubiquitination and degradation prevents adipocyte differentiation.	MKRN4P MKRN1	2.81e-05	3	107	2	24336050
Pubmed	Polycomb group targeting through different binding partners of RING1B C-terminal domain.	RYBP RNF2	2.81e-05	3	107	2	20696397
Pubmed	The H3K36me2 Methyltransferase Nsd1 Demarcates PRC2-Mediated H3K27me2 and H3K27me3 Domains in Embryonic Stem Cells.	NSD1 SUZ12	2.81e-05	3	107	2	29606589
Pubmed	MAP kinase pathway-dependent phosphorylation of the L1-CAM ankyrin binding site regulates neuronal growth.	ANK1 ANK2	2.81e-05	3	107	2	16597699
Pubmed	Proteins ZNF198 and SUZ12 are down-regulated in hepatitis B virus (HBV) X protein-mediated hepatocyte transformation and in HBV replication.	ZMYM2 SUZ12	2.81e-05	3	107	2	21480320
Pubmed	SIRT1 Activation Attenuates Bone Cancer Pain by Inhibiting mGluR1/5.	GRM1 GRM5	2.81e-05	3	107	2	31270711
Pubmed	Acceleration of gastric tumorigenesis through MKRN1-mediated posttranslational regulation of p14ARF.	MKRN4P MKRN1	2.81e-05	3	107	2	23104211
Pubmed	Enhanced endocannabinoid signaling elevates neuronal excitability in fragile X syndrome.	GRM1 GRM5	2.81e-05	3	107	2	20410124
Pubmed	RYBP modulates stability and function of Ring1B through targeting UBE3A.	RYBP RNF2	2.81e-05	3	107	2	30040487
Pubmed	Binding of an ankyrin-1 isoform to obscurin suggests a molecular link between the sarcoplasmic reticulum and myofibrils in striated muscles.	ANK1 ANK2	2.81e-05	3	107	2	12527750
Pubmed	Increased expression of the TNF superfamily member LIGHT/TNFSF14 and its receptors (HVEM and LTßR) in patients with systemic sclerosis.	TNFRSF14 LTBR	2.81e-05	3	107	2	30508197
Pubmed	The regulation of hippocampal LTP by the molecular switch, a form of metaplasticity, requires mGlu5 receptors.	GRM1 GRM5	2.81e-05	3	107	2	16024054
Pubmed	Human ankyrins and their contribution to disease biology: An update.	ANK1 ANK2	2.81e-05	3	107	2	33410423
Pubmed	The ancient source of a distinct gene family encoding proteins featuring RING and C(3)H zinc-finger motifs with abundant expression in developing brain and nervous system.	MKRN4P MKRN1	2.81e-05	3	107	2	10843807
Pubmed	Proinflammatory effects of LIGHT through HVEM and LTbetaR interactions in cultured human umbilical vein endothelial cells.	TNFRSF14 LTBR	2.81e-05	3	107	2	15917993
Pubmed	Regulation of the mGluR5, EAAT1 and GS expression by glucocorticoids in MG-63 osteoblast-like osteosarcoma cells.	GRM5 GLUL	2.81e-05	3	107	2	17627080
Pubmed	mGluR1 and mGluR5 Synergistically Control Cholinergic Synaptic Transmission in the Thalamic Reticular Nucleus.	GRM1 GRM5	2.81e-05	3	107	2	27466334
Pubmed	Genetic reduction of group 1 metabotropic glutamate receptors alters select behaviors in a mouse model for fragile X syndrome.	GRM1 GRM5	2.81e-05	3	107	2	21571007
Pubmed	Synaptotagmin 2 couples mucin granule exocytosis to Ca2+ signaling from endoplasmic reticulum.	ANK2 SYTL2	2.81e-05	3	107	2	19208631
Pubmed	Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome.	GRM1 GRM5	2.81e-05	3	107	2	20534533
Pubmed	Interpretation of genetic association studies: markers with replicated highly significant odds ratios may be poor classifiers.	CFH C2	2.81e-05	3	107	2	19197355
Pubmed	Metabotropic glutamate receptors 1 and 5 differentially regulate bulbar dopaminergic cell function.	GRM1 GRM5	2.81e-05	3	107	2	20692242
Pubmed	Herpesvirus entry mediator (TNFRSF14) regulates the persistence of T helper memory cell populations.	TNFRSF14 LTBR	2.81e-05	3	107	2	21402741
Pubmed	Ankyrin-dependent Na+ channel clustering prevents neuromuscular synapse fatigue.	ANK1 ANK2	2.81e-05	3	107	2	34289389
Pubmed	PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos.	RNF2 SUV39H1 SUZ12	3.62e-05	21	107	3	18311137
Pubmed	UPF2 is a critical regulator of liver development, function and regeneration.	TUT7 C2 ALB	5.47e-05	24	107	3	20657840
Pubmed	Association between polymorphisms of complement pathway genes and age-related macular degeneration in a Chinese population.	CFH C2	5.60e-05	4	107	2	23233260
Pubmed	Functional partnership between mGlu3 and mGlu5 metabotropic glutamate receptors in the central nervous system.	GRM1 GRM5	5.60e-05	4	107	2	29079293
Pubmed	Interactions between ephrin-B and metabotropic glutamate 1 receptors in brain tissue and cultured neurons.	GRM1 GRM5	5.60e-05	4	107	2	15745950
Pubmed	A20 Promotes Ripoptosome Formation and TNF-Induced Apoptosis via cIAPs Regulation and NIK Stabilization in Keratinocytes.	BIRC3 TNFAIP3	5.60e-05	4	107	2	32028675
Pubmed	Langerhans Cells Control Lymphatic Vessel Function during Inflammation via LIGHT-LTβR Signaling.	TNFRSF14 LTBR	5.60e-05	4	107	2	30952816
Pubmed	Association Between Complement Factor C2/C3/CFB/CFH Polymorphisms and Age-Related Macular Degeneration: A Meta-Analysis.	CFH C2	5.60e-05	4	107	2	30179527
Pubmed	Facilitating T Cell Infiltration in Tumor Microenvironment Overcomes Resistance to PD-L1 Blockade.	TNFRSF14 LTBR	5.60e-05	4	107	2	26977880
Pubmed	LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediator.	TNFRSF14 LTBR	5.60e-05	4	107	2	9462508
Pubmed	Metabotropic glutamate receptors transduce signals for neurite outgrowth after binding of the prion protein to laminin γ1 chain.	GRM1 GRM5	5.60e-05	4	107	2	20876210
Pubmed	PLK1 and HOTAIR Accelerate Proteasomal Degradation of SUZ12 and ZNF198 during Hepatitis B Virus-Induced Liver Carcinogenesis.	ZMYM2 SUZ12	5.60e-05	4	107	2	25855382
Pubmed	Decreased nociceptive sensitization in mice lacking the fragile X mental retardation protein: role of mGluR1/5 and mTOR.	GRM1 GRM5	5.60e-05	4	107	2	18094233
Pubmed	Differential cellular expression of LIGHT and its receptors in early gestation human placentas.	TNFRSF14 LTBR	5.60e-05	4	107	2	17010447
Pubmed	Phylogenetic conservation of the makorin-2 gene, encoding a multiple zinc-finger protein, antisense to the RAF1 proto-oncogene.	MKRN4P MKRN1	5.60e-05	4	107	2	11597136
Pubmed	C2 and CFB genes in age-related maculopathy and joint action with CFH and LOC387715 genes.	CFH C2	5.60e-05	4	107	2	18493315
Pubmed	[Polymorphisms of complement factor genes and age-related macular degeneration in a German population].	CFH C2	5.60e-05	4	107	2	19399715
Pubmed	The critical role of LIGHT in promoting intestinal inflammation and Crohn's disease.	TNFRSF14 LTBR	5.60e-05	4	107	2	15944326
Pubmed	Differential expression of LIGHT and its receptors in human placental villi and amniochorion membranes.	TNFRSF14 LTBR	5.60e-05	4	107	2	12466117
Pubmed	Contribution of the lymphotoxin beta receptor to liver regeneration.	TNFRSF14 LTBR	5.60e-05	4	107	2	16002734
Pubmed	Inhibition of c3 convertase activity by hepatitis C virus as an additional lesion in the regulation of complement components.	CFH C2	5.60e-05	4	107	2	24983375
Pubmed	Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression.	GRM1 GRM5	5.60e-05	4	107	2	15254091
Pubmed	The SRA protein UHRF1 promotes epigenetic crosstalks and is involved in prostate cancer progression.	SUV39H1 SUZ12	5.60e-05	4	107	2	22330138
Pubmed	A variant NuRD complex containing PWWP2A/B excludes MBD2/3 to regulate transcription at active genes.	PWWP2A PWWP2B	5.60e-05	4	107	2	30228260
Pubmed	Do transmembrane domain neuregulin 1 mutant mice exhibit a reliable sensorimotor gating deficit?	GRM1 GRM5	5.60e-05	4	107	2	21605597
Pubmed	Polycomb complexes repress developmental regulators in murine embryonic stem cells.	RNF2 SUZ12	5.60e-05	4	107	2	16625203
Pubmed	Functional interactions between ubiquitin E2 enzymes and TRIM proteins.	TRIM31 TRIM10 TRIM17	7.85e-05	27	107	3	21143188
Pubmed	Functional proteomics mapping of a human signaling pathway.	SYTL2 ZMYM2 SKI ANKRD27 FBLN1 GLUL RABGEF1 TNFAIP3 ZBTB11	9.10e-05	591	107	9	15231748
Pubmed	Polymorphisms in genes of the steroid receptor superfamily modify postmenopausal breast cancer risk associated with menopausal hormone therapy.	AR NR1I2	9.32e-05	5	107	2	19739075
Pubmed	LIGHT/TNFSR14 can regulate hepatic lipase expression by hepatocytes independent of T cells and Kupffer cells.	TNFRSF14 LTBR	9.32e-05	5	107	2	23355893
Interaction	UBE2D3 interactions	MKRN3 MKRN1 TRIM31 BIRC3 TRIM10 RNF2 RNF5 TRIM17 RABGEF1 TNFAIP3	2.27e-06	283	105	10	int:UBE2D3
Interaction	UBE2D4 interactions	MKRN3 MKRN1 TRIM31 TRIM10 RNF2 RNF5 TRIM17	2.96e-06	119	105	7	int:UBE2D4
Interaction	UBE2D1 interactions	MKRN3 MKRN1 TRIM31 BIRC3 TRIM10 RNF2 RNF5 TRIM17 RABGEF1 TNFAIP3	3.19e-06	294	105	10	int:UBE2D1
Interaction	KIAA1958 interactions	ZMYM2 TCEANC KIAA1958 SUZ12	4.73e-06	22	105	4	int:KIAA1958
Interaction	UBE2W interactions	MKRN3 MKRN1 TRIM31 RNF2 RNF5 TRIM17	1.10e-05	96	105	6	int:UBE2W
GeneFamily	Ring finger proteins	MKRN3 MKRN4P MKRN1 TRIM31 BIRC3 TRIM10 RNF2 RNF5 TRIM17	1.78e-06	275	74	9	58
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SELE CFH SRPX2 C2 C6	3.55e-06	57	74	5	1179
GeneFamily	PWWP domain containing	NSD1 PWWP2A PWWP2B	9.58e-05	22	74	3	1147
GeneFamily	Complement system\|Sushi domain containing	CFH C2 C6	4.26e-04	36	74	3	492
GeneFamily	Glutamate metabotropic receptors\|Protein phosphatase 1 regulatory subunits	GRM1 GRM5	4.55e-04	8	74	2	281
GeneFamily	VPS9 domain containing	ANKRD27 RABGEF1	7.28e-04	10	74	2	928
GeneFamily	Ankyrin repeat domain containing	ANK1 ANK2 ANKRD27 SNCAIP RAI14	3.14e-03	242	74	5	403
GeneFamily	CD molecules\|Tumor necrosis factor receptor superfamily\|Death inducing signaling complex	TNFRSF14 LTBR	6.25e-03	29	74	2	782
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM31 TRIM10 TRIM17	6.96e-03	95	74	3	59
Coexpression	SMID_BREAST_CANCER_LUMINAL_B_DN	SELE ANK2 BIRC3 CORO1A FBLN1 SNCAIP VNN2 JCHAIN PCOLCE2 LTBP1 TNFAIP3 FHL1	5.10e-06	587	107	12	M17572
Coexpression	VALK_AML_CLUSTER_6	CFH CORO1A SNCAIP LTBP1	1.11e-05	34	107	4	M4965
CoexpressionAtlas	Stromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4	GAS1 AR FBLN1 BMPR1A SLC44A1 SRPX2 PCSK6 PCOLCE2 LTBP1 BMPER FHL1	1.09e-05	437	105	11	GSM777046_500
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	SELE CFH ANK2 GAS1 COL6A5 FBLN1 BMPR1A SRPX2 RAI14 LTBP1 FHL1	1.29e-05	445	105	11	GSM777043_500
CoexpressionAtlas	DevelopingKidney_e15.5_Endothelial cells_emap-29965_k-means-cluster#4_top-relative-expression-ranked_200	STAB2 THSD1 CORO1A TNFAIP3 MAP4K2	6.81e-05	86	105	5	gudmap_developingKidney_e15.5_Endothelial cells_200_k4
CoexpressionAtlas	kidney_adult_JuxtaGlom_Ren1_k-means-cluster#1_top-relative-expression-ranked_1000	CFH SYTL2 LMO7 ALB FHL1	8.46e-05	90	105	5	gudmap_kidney_adult_JuxtaGlom_Ren1_k1_1000
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 GAS1 SYTL2 ZNF385A TMEFF2 PCSK6 GLUL PCOLCE2 FHL1	8.08e-10	188	107	9	7191087d8754f5e8700e3d744cd920ee26db1e57
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 ZNF385A AR FBLN1 PCSK6 PCOLCE2 LTBP1 FHL1	1.07e-09	194	107	9	ce32e60bcea1b8baf496ce9050832bc8c77d8434
ToppCell	droplet-Heart-nan-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 ZNF385A AR FBLN1 PCSK6 PCOLCE2 LTBP1 FHL1	1.07e-09	194	107	9	a1dc157148885cc8d3685ac81a1f4e3562aeecc9
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH ADAMTS19 ZNF385A TMEFF2 FBLN1 PCSK6 PCOLCE2 FHL1	1.62e-08	185	107	8	d5f5866924648a3c14e2596218fd548a31777aa3
ToppCell	(0)_MSCs\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CFH ESM1 MDK AR LMO7 C2 LTBP1 C6	1.69e-08	186	107	8	a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell	(0)_MSCs-(00)_Lepr-MSC\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	CFH ESM1 MDK AR LMO7 C2 LTBP1 C6	1.69e-08	186	107	8	f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 COL6A5 MDK TMEFF2 FBLN1 LTBP1 BMPER	2.07e-08	191	107	8	6cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 COL6A5 MDK TMEFF2 FBLN1 LTBP1 BMPER	2.07e-08	191	107	8	850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 COL6A5 MDK TMEFF2 FBLN1 LTBP1 BMPER	2.07e-08	191	107	8	8b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCell	facs-Aorta-Heart-18m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK TMEFF2 FBLN1 C2 PCOLCE2 BMPER	2.07e-08	191	107	8	6242f83acaf1714e9c1771a832cb67674b19e96d
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 FBLN1 SRPX2 PCSK6 PCOLCE2 BMPER FHL1	2.07e-08	191	107	8	1efb47743b6834b64cb0f61721ddbe875b1a66ca
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 FBLN1 SRPX2 PCSK6 PCOLCE2 BMPER FHL1	2.16e-08	192	107	8	5e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 FBLN1 SRPX2 PCSK6 PCOLCE2 BMPER FHL1	2.16e-08	192	107	8	136af0186c70c14c5f2b33ed7a148156de5b478c
ToppCell	facs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK FBLN1 SRPX2 PCSK6 PCOLCE2 FHL1	2.25e-08	193	107	8	735a72fac16397edde95e8eefa6f83caeb5ee5df
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH GAS1 MDK FBLN1 SRPX2 C2 PCOLCE2 FHL1	2.25e-08	193	107	8	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCell	facs-Heart-RV-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK FBLN1 SRPX2 PCSK6 PCOLCE2 FHL1	2.25e-08	193	107	8	ff901d2f3d7a511639c1e3b76058896c0d8a8602
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CFH GAS1 MDK FBLN1 SRPX2 C2 PCOLCE2 FHL1	2.25e-08	193	107	8	30481fb01c7acf85beae10213f038da86bed6777
ToppCell	facs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK CCNG2 FBLN1 PCSK6 PCOLCE2 FHL1	2.34e-08	194	107	8	48063c9fe3e12aeff0707acada1baa2f8621f093
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH ANK2 GAS1 TMEFF2 FBLN1 PCOLCE2 LTBP1 FHL1	2.34e-08	194	107	8	35b30bc954750e939f81a9a7498b8bc2ce69a299
ToppCell	facs-Heart-RA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK CCNG2 FBLN1 PCSK6 PCOLCE2 FHL1	2.34e-08	194	107	8	4f31d2cf7eb37b45fefc4da5b41aac0bfdd847b3
ToppCell	droplet-Heart-nan-18m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ANK2 GAS1 MDK FBLN1 PCSK6 PCOLCE2 FHL1	2.34e-08	194	107	8	20a0439fa02c5f8107612e34c7ab54120b9b8573
ToppCell	facs-Heart-RA-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK CCNG2 FBLN1 PCSK6 PCOLCE2 FHL1	2.64e-08	197	107	8	940cf1e54d7c820e04946258a8b784f35c6a144c
ToppCell	Parenchymal-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CFH ADAMTS19 THSD1 MDK PTPN9 SLC44A1 SRPX2 PTCH2	2.96e-08	200	107	8	8a4c210a3130f7baedf15ecbc0f4903b97da0352
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH ANK2 GAS1 ATP8B2 TMEFF2 FBLN1 LTBP1	2.00e-07	172	107	7	e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFH ANK2 GAS1 FBLN1 SRPX2 LMX1A LTBP1	2.33e-07	176	107	7	2e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCell	343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFH ANK2 GAS1 FBLN1 SRPX2 LMX1A LTBP1	2.33e-07	176	107	7	f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 TMEFF2 FBLN1 SRPX2 PCOLCE2 BMPER	2.82e-07	181	107	7	269b39ac65790061d54eab47a8eeb024403f0348
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 TMEFF2 FBLN1 SRPX2 PCOLCE2 BMPER	2.82e-07	181	107	7	cd4f744b6b64ba6c22ec07afd1d3058a2546909d
ToppCell	facs-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 TMEFF2 FBLN1 SRPX2 PCOLCE2 BMPER	2.82e-07	181	107	7	c8395ae872aa80b3ae1ab7c53e57b3ca15aeb0e2
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS1 DDO MDK FBLN1 SNCAIP PTCH2 C2	2.93e-07	182	107	7	904804813849b7f7f716ba1554d33b07bc0a701e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS1 DDO MDK FBLN1 SNCAIP PTCH2 C2	2.93e-07	182	107	7	5d8b7fe18286e27f0f50c5d2d9be56850e2cb8f4
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH TMEFF2 FBLN1 PCSK6 C2 PCOLCE2 FHL1	3.04e-07	183	107	7	5cfcd589a480e67654d3d94e71916f122150db10
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH TMEFF2 FBLN1 PCSK6 C2 PCOLCE2 FHL1	3.04e-07	183	107	7	c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH TMEFF2 FBLN1 PCSK6 C2 PCOLCE2 FHL1	3.04e-07	183	107	7	81003ddc24164959dd41bb12fcac72638789b8f2
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK FBLN1 C2 PCOLCE2 LTBP1	3.04e-07	183	107	7	63294d66e3ccf152ffe5d1237106764c14390b62
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK FBLN1 C2 PCOLCE2 LTBP1	3.04e-07	183	107	7	7e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCell	COVID-19-Heart-Fib_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GAS1 FBLN1 SRPX2 LMX1A PCSK6 PCOLCE2 LTBP1	3.27e-07	185	107	7	8f95d8e591bf7379d13f5a0545b0cb49e2b1ab5d
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l20-25\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ZNF385A TMEFF2 LMX1A PCSK6 PCOLCE2 LTBP1 FHL1	3.52e-07	187	107	7	0d4b7da81036c2aa678654b9fe49c939d08fcd9b
ToppCell	facs-Trachea-nan-24m-Mesenchymal-fibroblast\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH TMEFF2 FBLN1 PCSK6 PCOLCE2 LTBP1 FHL1	3.52e-07	187	107	7	b930d5f7d410ac1f340babec5c937388f64cafc0
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH ZNF385A TMEFF2 FBLN1 GLUL C2 FHL1	3.52e-07	187	107	7	6f47a80e612b320f571210483e62ff5db2a8ea43
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ANK2 GAS1 COL6A5 MDK FBLN1 TAFA1 FHL1	3.78e-07	189	107	7	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF385A TMEFF2 SRPX2 PCSK6 GLUL PCOLCE2 LTBP1	3.78e-07	189	107	7	6e52cac679e0541ca5f2be316bdabdbc34da6e18
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ZNF385A TMEFF2 FBLN1 SRPX2 PCOLCE2 FHL1	3.78e-07	189	107	7	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK1 GAS1 MDK FBLN1 PCSK6 PCOLCE2 FHL1	3.78e-07	189	107	7	2a5fda73d38bdc23cf47e5335ffd4e086e990245
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 FBLN1 LMX1A C2 PCOLCE2 FHL1	3.91e-07	190	107	7	97772e69e6f51ebffbb5433ca7b40f1048723220
ToppCell	droplet-Lung-nan-18m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 FBLN1 LMX1A C2 PCOLCE2 FHL1	3.91e-07	190	107	7	72c2b824acdc43139e6635785df3ed3feb58ec46
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS1 ZNF385A TMEFF2 FBLN1 C2 PCOLCE2 FHL1	3.91e-07	190	107	7	47077579496c5340e99f61499427a3a36b566da3
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH GAS1 FBLN1 SRPX2 PCOLCE2 BMPER FHL1	4.06e-07	191	107	7	36467322096bc766cd777dae3bfb4e65511e492c
ToppCell	P07-Mesenchymal-mesenchymal_fibroblast\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CFH GAS1 MDK SRPX2 PCOLCE2 BMPER FHL1	4.06e-07	191	107	7	a05e9a7eb137d804570dd7d8905975d735738767
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-alveolar_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH GAS1 FBLN1 SRPX2 PCOLCE2 BMPER FHL1	4.06e-07	191	107	7	94795daf05061baa3b72a1b01c9e940af86de044
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH GAS1 MDK FBLN1 PCOLCE2 LTBP1 FHL1	4.06e-07	191	107	7	ce80f65bd24b1c4d2152bf45248449e7a1a97e56
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK FBLN1 PCSK6 PCOLCE2 FHL1	4.06e-07	191	107	7	44631226f59364098a7dd58058e6970a75441009
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH GAS1 FBLN1 SRPX2 PCOLCE2 LTBP1 FHL1	4.06e-07	191	107	7	d04e6292fef189b8d8ed0f4b0c310b2b250fd30e
ToppCell	droplet-Heart-4Chambers-21m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK FBLN1 PCSK6 PCOLCE2 FHL1	4.06e-07	191	107	7	f892f725a32e704cd18fec2f6d1db82993e7e79a
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH GAS1 FBLN1 SRPX2 PCOLCE2 LTBP1 FHL1	4.06e-07	191	107	7	de3e9b704621b26836c2ddc39fa3e840dfb4541b
ToppCell	facs-Aorta-Heart-18m-Mesenchymal\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK TMEFF2 FBLN1 C2 PCOLCE2	4.20e-07	192	107	7	6d4fe7ea278efa4b9d43f8a3c282bc0e0e9abaea
ToppCell	droplet-Lung-1m-Mesenchymal\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH GAS1 MDK FBLN1 PCOLCE2 LTBP1 FHL1	4.20e-07	192	107	7	01433bd4794b8bcc51fe4249124a0f4289b9d6e2
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFH ADAMTS19 ANK2 GAS1 FBLN1 PTCH2 FHL1	4.20e-07	192	107	7	8d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH COL6A5 TMEFF2 FBLN1 SRPX2 PCOLCE2 BMPER	4.20e-07	192	107	7	853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBLN1 SRPX2 PCOLCE2 LTBP1 BMPER FHL1	4.20e-07	192	107	7	d22c1135867bcb9076435e2c6eb1cc1248990d0c
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH GAS1 FBLN1 PCSK6 PCOLCE2 LTBP1 FHL1	4.20e-07	192	107	7	321850b0f881420c2d57d3e825e365c82fa511ab
ToppCell	facs-Aorta-Heart-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK TMEFF2 FBLN1 C2 PCOLCE2	4.20e-07	192	107	7	2c6406bc97c3224099b94a43f2890f057b528fa6
ToppCell	droplet-Lung-nan-18m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH FBLN1 SRPX2 PCOLCE2 LTBP1 BMPER FHL1	4.20e-07	192	107	7	c09966f4d63a739a56db4df7e0e0ee9ecacd21ad
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH COL6A5 TMEFF2 FBLN1 SRPX2 PCOLCE2 BMPER	4.20e-07	192	107	7	d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH GAS1 MDK FBLN1 C2 PCOLCE2 FHL1	4.20e-07	192	107	7	1b228f0929b505de82a39bf64c837887b0e56701
ToppCell	facs-Aorta-Heart-18m-Mesenchymal-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK TMEFF2 FBLN1 C2 PCOLCE2	4.20e-07	192	107	7	47aed7c8e6f5ce1084821212a04f568319e65fd6
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast-fibroblast_of_trachea\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH GAS1 FBLN1 PCSK6 PCOLCE2 LTBP1 FHL1	4.20e-07	192	107	7	cf2765d8bc074f7f9ee864eae632a3b705175842
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH COL6A5 TMEFF2 FBLN1 SRPX2 PCOLCE2 BMPER	4.20e-07	192	107	7	49281626ecad0456fdbded2378b7028d7b589686
ToppCell	(2)_5-FU-(2)_LEPR+_perivascular_cells_and_VE-Cad+_vascular_cells_(mixed)\|World / Stress and Cell class	CFH MDK AR LMO7 C2 LTBP1 FHL1	4.35e-07	193	107	7	f31398dad5321a7bcb27e208bd73630e9756e897
ToppCell	facs-Heart-RV-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK FBLN1 PCSK6 PCOLCE2 FHL1	4.35e-07	193	107	7	76f0f8569255d6cdf1e3b8e954cae72e71f87157
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 FBLN1 SRPX2 PCOLCE2 BMPER FHL1	4.35e-07	193	107	7	027e098ad018e782287f84eee0f77551018f2196
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFH GAS1 MDK FBLN1 C2 PCOLCE2 FHL1	4.35e-07	193	107	7	fe9720185929ef849edd1b8eb4854306b392e5a2
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 FBLN1 SRPX2 PCOLCE2 BMPER FHL1	4.35e-07	193	107	7	c5463a87f20b3a7f7ffda677b2f5a0e9e49d6685
ToppCell	facs-Lung-EPCAM-3m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 FBLN1 SRPX2 PCOLCE2 BMPER FHL1	4.35e-07	193	107	7	abdfb8b1dbdcb424042e21017a9e829fced4457e
ToppCell	droplet-Heart-nan-24m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 CCNG2 FBLN1 PCSK6 PCOLCE2 FHL1	4.35e-07	193	107	7	d08919db9601941569b9a143dad4d8e6f56a4389
ToppCell	facs-Heart-RA-3m-Mesenchymal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK FBLN1 PCSK6 PCOLCE2 FHL1	4.50e-07	194	107	7	c422aeddb4e949a22f731da675bdf91dee86ba61
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS1 ZNF385A TMEFF2 FBLN1 PCOLCE2 LTBP1 FHL1	4.50e-07	194	107	7	9709dc95fb6982b6a0467b507845d5bc17252e3e
ToppCell	facs-GAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS1 ZNF385A TMEFF2 FBLN1 PCOLCE2 LTBP1 FHL1	4.50e-07	194	107	7	93b7a9065430740ec31fce4e8c14ffccb498591d
ToppCell	facs-GAT-Fat-18m-Mesenchymal\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS1 ZNF385A TMEFF2 FBLN1 PCOLCE2 LTBP1 FHL1	4.50e-07	194	107	7	0d2e65b44e3f143971c2fd24c4552f042b049cfa
ToppCell	ASK428-Mesenchymal\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	CFH ANK2 COL6A5 FBLN1 SRPX2 LTBP1 BMPER	4.66e-07	195	107	7	2b156163975d9a3d3fda1402acd9831d0fdc9e25
ToppCell	droplet-Heart-nan-18m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK FBLN1 PCSK6 PCOLCE2 FHL1	4.66e-07	195	107	7	613bea20c3d82c22a6af4c1a668af6fcf11fec0a
ToppCell	droplet-Heart-nan-18m-Mesenchymal-fibroblast\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 MDK FBLN1 PCSK6 PCOLCE2 FHL1	4.66e-07	195	107	7	9ffabd831c2a0de3597f328e83db7ee259cb0ccc
ToppCell	ASK428-Mesenchymal-Fibroblast\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	CFH ANK2 COL6A5 FBLN1 SRPX2 LTBP1 BMPER	4.66e-07	195	107	7	c269c0d894a0f55da6495b59d4b9abb9f68df684
ToppCell	facs-Thymus-Thymus_Epithelium\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ANK2 GAS1 COL6A5 FBLN1 C2 LTBP1	4.83e-07	196	107	7	6bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCell	facs-Thymus-Thymus_Epithelium-18m\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH ANK2 GAS1 COL6A5 FBLN1 C2 LTBP1	4.83e-07	196	107	7	c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCell	facs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 FBLN1 PCSK6 PCOLCE2 LTBP1 FHL1	4.83e-07	196	107	7	ad1838dabd043cb140260843e3527d8c7d58850e
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Adventitial_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	CFH ADAMTS19 GAS1 FBLN1 PTCH2 PCOLCE2 FHL1	4.83e-07	196	107	7	eed9fe83ffc1f79493b70778962a671dd9f481e0
ToppCell	facs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFH GAS1 FBLN1 PCSK6 PCOLCE2 LTBP1 FHL1	4.83e-07	196	107	7	cbc15c0769016fe9972445169029bd8d14a7e6ef
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CFH ANK2 ESM1 MDK RAI14 BMPER FHL1	5.35e-07	199	107	7	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CFH ANK2 ESM1 MDK RAI14 BMPER FHL1	5.35e-07	199	107	7	251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MDK FBLN1 SRPX2 SNCAIP PCOLCE2 BMPER FHL1	5.35e-07	199	107	7	2cec0e370ee9bb3c88a7acb5519e9ea8ddb399bc
ToppCell	343B-Fibroblasts-Fibroblast-F\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFH ANK2 GAS1 FBLN1 SRPX2 PCOLCE2 LTBP1	5.35e-07	199	107	7	b877c1d24357249781032e99d4237f72789cc9b8
ToppCell	Fibroblasts-CD34+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	CFH ANK2 GAS1 MDK FBLN1 LTBP1 FHL1	5.35e-07	199	107	7	13ff7409e200a0b46cdb7924d15ef33639693622
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH ANK2 GAS1 FBLN1 SRPX2 LTBP1 FHL1	5.35e-07	199	107	7	0019cfaa586a450c2e4952d1184a540561c8d0ba
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-RGCs_3\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	GAS1 MDK CDC45 EFNA4 SNCAIP LTBP1 CTPS1	5.35e-07	199	107	7	79d87e2b0adeff2d33c3b699afe7211fddc4f285
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MDK FBLN1 SRPX2 SNCAIP PCOLCE2 BMPER FHL1	5.35e-07	199	107	7	9e87b64e16d595701c3beb07aa835afe3330bd10
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFH ANK2 GAS1 COL6A5 FBLN1 LTBP1 FHL1	5.35e-07	199	107	7	fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CFH ANK2 ESM1 MDK RAI14 BMPER FHL1	5.35e-07	199	107	7	117f4f43b6c06dda553799b1063e827bce697370
ToppCell	343B-Fibroblasts-Fibroblast-F-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CFH ANK2 GAS1 FBLN1 SRPX2 PCOLCE2 LTBP1	5.35e-07	199	107	7	e32fa66f3361474088ba1dd58574822537950d59
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CFH ZNF385A FBLN1 SRPX2 GLUL PCOLCE2 FHL1	5.53e-07	200	107	7	933b5b400e48a511ba0a056be1d33d3610b5f10d
Drug	Selegiline hydrochloride [14611-52-0]; Up 200; 17.8uM; MCF7; HT_HG-U133A	CHST5 FBLN1 DOK4 VNN2 PCSK6 ALB TNFAIP3 C6	3.19e-06	193	105	8	4146_UP
Drug	pendimethalin	AR NR1I2 ALB	3.29e-06	7	105	3	ctd:C030856
Drug	rosiglitazone; Down 200; 10uM; MCF7; HT_HG-U133A	SKI ATP8B2 CORO1A R3HCC1L DOK4 SEC23IP RAI14 TNFAIP3	4.15e-06	200	105	8	5230_DN
Drug	Digoxigenin [1672-46-4]; Up 200; 10.2uM; HL60; HT_HG-U133A	ZMYM2 BIRC3 GRM1 SRPX2 DOK4 TNFAIP3 ZBTB11	1.83e-05	177	105	7	3060_UP
Drug	xanthanoic acid	GRM1 GRM5	2.11e-05	2	105	2	CID000065736
Drug	chlormethoxynil	AR NR1I2	2.11e-05	2	105	2	ctd:C054410
Drug	meprednisone	AR ALB	2.11e-05	2	105	2	ctd:C008352
Drug	Cp-asp	CFH FHL1	2.11e-05	2	105	2	CID000132878
Drug	pencycuron	AR NR1I2	2.11e-05	2	105	2	ctd:C036791
Disease	neurexophilin-1 measurement	CFH PCSK6 C2	2.22e-06	8	102	3	EFO_0008244
Disease	Dermatitis, Irritant	TRIM31 TRIM10 C2	3.32e-06	9	102	3	C0162823
Disease	spina bifida (biomarker_via_orthology)	RNF2 SUZ12	1.18e-05	2	102	2	DOID:0080016 (biomarker_via_orthology)
Disease	WAP four-disulfide core domain protein 5 measurement	CFH C2	3.54e-05	3	102	2	EFO_0803264
Disease	vesicle-associated membrane protein 8 measurement	CFH C2	3.54e-05	3	102	2	EFO_0803254
Disease	B-cell lymphoma 6 protein measurement	CFH C2	3.54e-05	3	102	2	EFO_0021933
Disease	interleukin-17F measurement	CFH C2	3.54e-05	3	102	2	EFO_0021963
Disease	cullin-9 measurement	CFH C2	7.07e-05	4	102	2	EFO_0802437
Disease	alanine aminotransferase 1 measurement	CFH C2	7.07e-05	4	102	2	EFO_0802260
Disease	Weaver syndrome	NSD1 SUZ12	1.18e-04	5	102	2	C0265210
Disease	cystatin-8 measurement	CFH C2	1.18e-04	5	102	2	EFO_0801509
Disease	ATP-dependent RNA helicase A measurement	CFH C2	1.18e-04	5	102	2	EFO_0802294
Disease	tight junction protein ZO-1 measurement	CFH C2	1.18e-04	5	102	2	EFO_0803155
Disease	thrombospondin type-1 domain-containing protein 1 measurement	CFH THSD1	1.18e-04	5	102	2	EFO_0802131
Disease	hephaestin-like protein 1 measurement	CFH C2	1.18e-04	5	102	2	EFO_0802597
Disease	synaptotagmin-like protein 4 measurement	CFH SRPX2	1.18e-04	5	102	2	EFO_0802109
Disease	interferon alpha-5 measurement	CFH C2	1.18e-04	5	102	2	EFO_0802642
Disease	Membranoproliferative Glomerulonephritis, Type I	CFH ALB	1.76e-04	6	102	2	C0268742
Disease	Membranoproliferative Glomerulonephritis, Type II	CFH ALB	1.76e-04	6	102	2	C0268743
Disease	Membranoproliferative Glomerulonephritis, Type III	CFH ALB	1.76e-04	6	102	2	C1720821
Disease	Complement deficiency disease	CFH C2 C6	2.03e-04	33	102	3	C0272242
Disease	factor VIII measurement, venous thromboembolism	STAB2 DGKZ ZNF160	2.22e-04	34	102	3	EFO_0004286, EFO_0004630
Disease	calcineurin subunit B type 1 measurement	PCSK6 C6	2.46e-04	7	102	2	EFO_0020215
Disease	baculoviral IAP repeat-containing protein 5 measurement	CFH C2	2.46e-04	7	102	2	EFO_0020174
Disease	C-C motif chemokine 1 measurement	CFH C2	2.46e-04	7	102	2	EFO_0008041
Disease	Headache, HOMA-B	SNCAIP TAFA1	2.46e-04	7	102	2	EFO_0004469, HP_0002315
Disease	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 measurement	CFH C2	2.46e-04	7	102	2	EFO_0020108
Disease	Glomerulonephritis, Membranoproliferative	CFH ALB	2.46e-04	7	102	2	C0017662
Disease	stabilin-2 measurement	CFH C2	3.27e-04	8	102	2	EFO_0020752
Disease	Alcohol withdrawal syndrome	AR GLUL	3.27e-04	8	102	2	C0236663
Disease	endothelin-converting enzyme 1 measurement	CFH PCOLCE2	4.19e-04	9	102	2	EFO_0008121
Disease	chronic central serous retinopathy	CFH ARFGEF1	4.19e-04	9	102	2	EFO_0009363
Disease	apolipoprotein D measurement	CFH C6	4.19e-04	9	102	2	EFO_0020156
Disease	complement factor B measurement	CFH C2	4.19e-04	9	102	2	EFO_0008096
Disease	kallikrein-14 measurement	CFH C6	4.19e-04	9	102	2	EFO_0020513
Disease	hemoglobin A1 measurement	ANK1 SKI ANKRD27 PTPN9 THADA PRDM11 PCOLCE2 MAP4K2	4.54e-04	520	102	8	EFO_0007629
Disease	brain ischemia (is_implicated_in)	SELE MDK	5.23e-04	10	102	2	DOID:2316 (is_implicated_in)
Disease	DNA repair protein rad51 homolog 1 measurement	CFH C2	5.23e-04	10	102	2	EFO_0020330
Disease	tropomyosin beta chain measurement	CFH C6	5.23e-04	10	102	2	EFO_0020787
Disease	obstructive jaundice (biomarker_via_orthology)	CFH ALB	5.23e-04	10	102	2	DOID:13603 (biomarker_via_orthology)
Disease	stromal interaction molecule 1 measurement	CFH C2	5.23e-04	10	102	2	EFO_0802093
Disease	tumor necrosis factor receptor superfamily member 11B measurement	CFH C6	6.38e-04	11	102	2	EFO_0020801
Disease	glycerol-3-phosphate dehydrogenase 1-like protein measurement	CFH C2	6.38e-04	11	102	2	EFO_0801640
Disease	tyrosine-protein kinase ZAP-70 measurement	CFH C6	7.64e-04	12	102	2	EFO_0020833
Disease	non-high density lipoprotein cholesterol measurement	TRIM31 NSD1 DGKZ WDPCP FBLN1 THADA NR1I2 C2 PCOLCE2	8.29e-04	713	102	9	EFO_0005689
Disease	smoking behavior, BMI-adjusted waist circumference	NSD1 RYBP RAI14 LTBP1	8.65e-04	122	102	4	EFO_0004318, EFO_0007789
Disease	transmembrane protein 87B measurement	CFH PCSK6	9.00e-04	13	102	2	EFO_0802158
Disease	tyrosine-protein phosphatase non-receptor type 1 measurement	CFH C2	9.00e-04	13	102	2	EFO_0020834
Disease	unipolar depression	CFH ATXN7L2 TRIM31 DDO GRM5 ANKRD27 WDPCP TRIM10 PRDM11 VNN2 PCSK6 BMPER	9.38e-04	1206	102	12	EFO_0003761
Disease	mosquito bite reaction itch intensity measurement, mosquito bite reaction size measurement	TRIM31 AR RNF2 RNF5 C2 LTBR	9.92e-04	328	102	6	EFO_0008377, EFO_0008378
Disease	reticulocyte measurement	ANK1 TUT7 MKRN1 GAS1 TRIM31 PEX12 SKI AR TRIM10 RAI14 PCOLCE2	1.05e-03	1053	102	11	EFO_0010700
Disease	wet macular degeneration	CFH C2	1.05e-03	14	102	2	EFO_0004683
Disease	colon cancer (is_marker_for)	BIRC3 CCNG2 TNFAIP3	1.13e-03	59	102	3	DOID:219 (is_marker_for)
Disease	pancreatic ductal carcinoma (is_marker_for)	RNF2 ALB MUC3A	1.25e-03	61	102	3	DOID:3587 (is_marker_for)
Disease	Urticaria	SELE ALB	1.38e-03	16	102	2	C0042109
Disease	cholangiocarcinoma (is_marker_for)	ALB TNFAIP3 MUC3A	1.43e-03	64	102	3	DOID:4947 (is_marker_for)
Disease	SLAM family member 7 measurement	CFH ITLN2	1.56e-03	17	102	2	EFO_0008287
Disease	Age-related macular degeneration	CFH C2	1.75e-03	18	102	2	cv:C0242383
Disease	cortical surface area change measurement, age at assessment	PCSK6 BMPER	1.95e-03	19	102	2	EFO_0008007, EFO_0021503
Disease	Lymphoma, Follicular	TNFRSF14 TNFAIP3	2.16e-03	20	102	2	C0024301
Disease	Attention Deficit Disorder	GRM1 GRM5	2.61e-03	22	102	2	C0041671
Disease	Minimal Brain Dysfunction	GRM1 GRM5	2.61e-03	22	102	2	C1321905
Disease	Epilepsy, Benign Psychomotor, Childhood	GRM1 GRM5	2.86e-03	23	102	2	C0393672
Disease	Epilepsy, Lateral Temporal	GRM1 GRM5	2.86e-03	23	102	2	C0393682
Disease	Uncinate Epilepsy	GRM1 GRM5	2.86e-03	23	102	2	C0014558
Disease	Epilepsy, Temporal Lobe	GRM1 GRM5	2.86e-03	23	102	2	C0014556
Disease	venous thromboembolism, tissue plasminogen activator measurement	DGKZ ZNF160	2.86e-03	23	102	2	EFO_0004286, EFO_0004791
Disease	Attention deficit hyperactivity disorder	GRM1 GRM5	3.11e-03	24	102	2	C1263846
Disease	reticulocyte count	ANK1 ZNF280C GAS1 TRIM31 PEX12 SKI AR TRIM10 THADA RAI14	3.34e-03	1045	102	10	EFO_0007986
Disease	atrophic macular degeneration	CFH C2	3.37e-03	25	102	2	EFO_1001492

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLKTKRPVISCNICQ	ZNF385A	66	Q96PM9
LCKCGRRSKRLVVSN	ERI2	596	A8K979
NCICRVPKSKLEVGR	BUD31	116	P41223
RVTKCCTESLVNRRP	ALB	496	P02768
KCPRIVSTSLDCLQK	ARFGEF1	91	Q9Y6D6
RTCAAPTRITCRLVK	ANK1	941	P16157
VGKEVKNSCRLCITP	H2AL3	66	A0A3B3IU63
KNSCRLCITPEHVKR	H2AL3	71	A0A3B3IU63
IRISQCKCTASDIKR	CCNG2	126	Q16589
RKCPICRSTIKGTVR	BIRC3	586	Q13489
ICTSCRDKRVRIIEP	CORO1A	191	P31146
RCIRVKTCSKSSIDI	CFH	441	P08603
VRSCLVPCEKTKTIR	FAM187A	236	A6NFU0
RQCGVINPETKKICT	ATXN7L2	241	Q5T6C5
INPETKKICTRLLTC	ATXN7L2	246	Q5T6C5
KAVICCRVTPLQKAQ	ATP8B2	801	P98198
KEFESRIVKSCPQCR	MKRN4P	356	Q13434
TCLQKTNRVCSKRGT	R3HCC1L	96	Q7Z5L2
CIRKLLQSKCPAESV	RAI14	101	Q9P0K7
KCSREKNKPQRSLVC	NSD1	601	Q96L73
KRVPRDKLACITKCS	RABGEF1	281	Q9UJ41
VRCTNPRKKCVLSTR	ADAMTS19	1061	Q8TE59
VPCLDQTRVKLTKRS	PTPN9	336	P43378
RTPVLCVAVKRQVLC	CDC42BPG	1191	Q6DT37
SQISVKISCCPRLKI	LRRC57	166	Q8N9N7
KIPDTKGCLQCRVVR	MAP4K2	591	Q12851
RKCTAPTRVTCRLVK	ANK2	996	Q01484
KCTSPQQKLVCLRKV	ANKRD27	276	Q96NW4
SKKSNIIRSVCSEPC	GRM5	501	P41594
KRVDKVCISSLCGRN	MOV10L1	181	Q9BXT6
RERTTRPPKCKEQCS	NFXL1	541	Q6ZNB6
CQETIRVTKPCTPKT	MDK	116	P21741
KVKKRTCCTACEPAR	CFAP65	1556	Q6ZU64
TRSLSKAVCKPVRCP	C2	76	P06681
GSVKTSRKCVSVCPL	PCSK6	721	P29122
VSSKPCRKVRETLAA	LMX1A	216	Q8TE12
RIKVVFTPSICKVTC	LTBP1	351	Q14766
PLVEATRLRCVTKCT	MUC3A	3166	Q02505
RIILVSKRSNCPKCG	DDIAS	31	Q8IXT1
RLQVSVCCKERKSES	EFNA4	146	P52798
TCPSKEKSNSCRILV	LMO7	616	Q8WWI1
KPTCKAVTCRAVRQP	SELE	296	P16581
VVCTLVLCSVQSPRK	METTL7B	141	Q6UX53
CKSTKRAIEPCLPRT	GAS1	136	P54826
RIIACKRKNPTSCSR	AR	841	P10275
KPTVALCQQKCRRTG	PCOLCE2	291	Q9UKZ9
KGACEITRKTRRQCQ	NR1I2	81	O75469
CQKKDTCRPQRGTVT	KIAA1328	461	Q86T90
KITNSPQKLISCRRE	IL20RB	276	Q6UXL0
CISKLVPRCSVTIIS	DDO	21	Q99489
KTDTVRCIKSCRPND	FBLN1	571	P23142
KILCNKCTTREDSPK	FHL1	86	Q13642
CIRNKIQCVSVTRIP	WDPCP	321	O95876
VTRIPLKSKAISCCR	WDPCP	331	O95876
SFVCSTKNRRCKLLP	CDC45	476	O75419
CRDSTVVCKRKCSHP	BMPER	261	Q8N8U9
KGRTECRNKQCIPIS	BMPER	326	Q8N8U9
CIEKQSKVRSVLRPS	C6	96	P13671
KRIIREICQSCGKTN	COL6A5	1176	A8TX70
KDSPKAQLRRTIECC	BMPR1A	111	P36894
FSSLPRSCKEIKERC	ITLN2	46	Q8WWU7
STTCPKCARLSLRKQ	DEF8	486	Q6ZN54
ECKSSPRCKRTVLDD	ESM1	36	Q9NQ30
KIKSVALCVAACPRQ	SLC44A1	106	Q8WWI5
VDNKCKCARITSRII	JCHAIN	31	P01591
SRRKCAACKIVVHTP	DGKZ	126	Q13574
KSGVVRSVCSEPCLK	GRM1	516	Q13255
RSVCSEPCLKGQIKV	GRM1	521	Q13255
LRPRQVLCEKCKSTL	PWWP2B	171	Q6NUJ5
CPKVTEISNVKCVTR	DOK4	56	Q8TEW6
ECPTCRKKLVSKRSL	RNF2	86	Q99496
KIIKSCPECRITSNF	MKRN1	326	Q9UHC7
RCKTRTLDSEPKCVE	GLUL	41	P15104
VKCTILPDTSRKSRQ	SYTL2	816	Q9HCH5
RSQTVKCSCLPGKVA	TAFA1	61	Q7Z5A9
RPRQVLCDKCKNSVV	PWWP2A	316	Q96N64
FKCPLCKTSVRKNAI	TRIM31	51	Q9BZY9
IKCSDPSSKLCATRR	THADA	1146	Q6YHU6
QKDVLCVCSSKTRVP	STK33	21	Q9BYT3
RQECPVCKAGISREK	RNF5	61	Q99942
VVVLCITRKCPRSNR	TMEFF2	336	Q9UIK5
ETRQKAACKSLPCAR	PTCH2	651	Q9Y6C5
TTSFCPNCIRLKKKV	PRDM11	441	Q9NQV5
CSICDVRKGTSTRKP	RYBP	41	Q8N488
CRCSNPLDTSVKEKI	CTPS1	216	P17812
SVTSLKTIPELCRRC	SNCAIP	21	Q9Y6H5
KRKLPVGACVSSVCV	SEC23IP	746	Q9Y6Y8
KTVCPLCRKTRVNDT	PEX12	301	O00623
LATCTQPRKRKLTVD	SKI	446	P12755
SPKKRVRIECKCGTE	SUV39H1	391	O43463
PRGTISKQDVCKTLC	CHST5	161	Q9GZS9
KCKTTNLTTCGRPVE	VNN2	406	O95498
CSKCQEKLDRSRPIS	ZBTB11	116	O95625
SCVKIARKPRTPECV	ZNF160	71	Q9HCG1
QKECSDKSCLRTPSL	UNC80	1526	Q8N2C7
VIDGTQTNKIKCRRC	TCEANC	286	Q8N8B7
RIVKSCPQCRVTSEL	MKRN3	356	Q13064
TSRPKCARASCKNIL	TNFAIP3	711	P21580
ASCKFIVKVQVRRCP	SRPX2	251	O60687
VCHKKRKDVSCPIRQ	SUZ12	191	Q15022
RVSSLSPSQCRKDKC	THSD1	786	Q9NS62
IGCQPKCVRTVITRE	STAB2	1321	Q8WWQ8
KPITCEECRKIFTSS	ZNF141	281	Q15928
EEIAPCTSKRKTQCR	LTBR	111	P36941
QKDQSPICVVCRESR	TRIM17	111	Q9Y577
NKSRCTICGKLTEIR	ZMYM2	421	Q9UBW7
STLIRCETRKCRKPV	TRIM10	256	Q9UDY6
CETRKCRKPVAVSPE	TRIM10	261	Q9UDY6
ECFKQVIRTCEKRPT	ZNF790	136	Q6PG37
CSTVGLIICVKRRKP	TNFRSF14	216	Q92956
RCPKCRLQFLTSKEK	ZNF280C	471	Q8ND82
TKGKSPTVVCSLCKR	TUT7	956	Q5VYS8
ICANDAIPKTCKRKT	TMA16	161	Q96EY4
PVKAKLDCNRTRDSC	KIAA1958	106	Q8N8K9