Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH17 DNAH2 DNAH1

4.66e-0518793GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH17 DNAH2 DNAH1

1.82e-0428793GO:0051959
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH17 DNAH2 DNAH1

4.20e-0437793GO:0045505
GeneOntologyBiologicalProcessaxoneme assembly

DNAH17 DNAH2 CFAP69 DNAH1 CFAP65

5.84e-05109785GO:0035082
GeneOntologyBiologicalProcessspermatogenesis

MORC1 TDRD5 TOPAZ1 KIAA0319L DAZL HSF2 CFAP69 SPATA32 PHC2 DNAH1 CFAP65

1.07e-047447811GO:0007283
GeneOntologyBiologicalProcessmale gamete generation

MORC1 TDRD5 TOPAZ1 KIAA0319L DAZL HSF2 CFAP69 SPATA32 PHC2 DNAH1 CFAP65

1.33e-047627811GO:0048232
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

MORC1 CREBRF ACSL4 TDRD5 HDAC4 TOPAZ1 KIAA0319L DAZL HSF2 CFAP69 SPATA32 PHC2 DNAH1 CFAP65

1.38e-0411947814GO:0048609
GeneOntologyBiologicalProcesscilium movement involved in cell motility

DNAH17 KIAA0319L DNAH2 CFAP69 DNAH1 CFAP65

1.45e-04210786GO:0060294
GeneOntologyBiologicalProcesscilium-dependent cell motility

DNAH17 KIAA0319L DNAH2 CFAP69 DNAH1 CFAP65

1.65e-04215786GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

DNAH17 KIAA0319L DNAH2 CFAP69 DNAH1 CFAP65

1.65e-04215786GO:0001539
GeneOntologyBiologicalProcessmicrotubule bundle formation

DNAH17 DNAH2 CFAP69 DNAH1 CFAP65

2.24e-04145785GO:0001578
GeneOntologyBiologicalProcesscilium assembly

C2CD3 TBC1D31 DNAH17 DNAH2 CPLANE1 CFAP69 DNAH1 CFAP65

2.72e-04444788GO:0060271
GeneOntologyBiologicalProcesssperm axoneme assembly

CFAP69 DNAH1 CFAP65

2.86e-0434783GO:0007288
GeneOntologyBiologicalProcessregulation of skeletal muscle fiber differentiation

NLN HDAC4

2.93e-047782GO:1902809
GeneOntologyCellularComponentaxonemal dynein complex

DNAH17 DNAH2 DNAH1

1.13e-0425793GO:0005858
HumanPhenoCoiled sperm flagella

DNAH17 DNAH2 CFAP69 DNAH1 CFAP65

2.76e-0732245HP:0032560
HumanPhenoShort sperm flagella

DNAH17 DNAH2 CFAP69 DNAH1 CFAP65

3.24e-0733245HP:0032559
HumanPhenoAbnormal sperm tail morphology

DNAH17 DNAH2 CFAP69 DNAH1 CFAP65

1.27e-0643245HP:0012868
HumanPhenoAbsent sperm flagella

DNAH17 DNAH2 DNAH1 CFAP65

7.20e-0628244HP:0032558
HumanPhenoAbnormal sperm morphology

DNAH17 DNAH2 CFAP69 DNAH1 CFAP65

1.10e-0566245HP:0012864
HumanPhenoAbnormal germ cell morphology

DNAH17 DNAH2 CFAP69 DNAH1 CFAP65

1.19e-0567245HP:0012862
HumanPhenoAbnormal male germ cell morphology

DNAH17 DNAH2 CFAP69 DNAH1 CFAP65

1.19e-0567245HP:0012863
HumanPhenoReduced sperm motility

DNAH17 DNAH2 CFAP69 DNAH1 CFAP65

1.37e-0569245HP:0012207
HumanPhenoAbnormal sperm motility

DNAH17 DNAH2 CFAP69 DNAH1 CFAP65

1.62e-04115245HP:0012206
HumanPhenoAbnormal sperm physiology

DNAH17 DNAH2 CFAP69 DNAH1 CFAP65

1.62e-04115245HP:0034809
DomainMARK/par1

MARK1 MARK2

1.00e-044772IPR033624
DomainKA1_dom

MARK1 MARK2

1.66e-045772IPR001772
DomainKA1

MARK1 MARK2

1.66e-045772PF02149
DomainKA1

MARK1 MARK2

1.66e-045772PS50032
Domain-

MARK1 MARK2

1.66e-0457723.30.310.80
DomainKA1/Ssp2_C

MARK1 MARK2

3.48e-047772IPR028375
DomainRuvA_2-like

FAAP24 SRBD1

5.93e-049772IPR010994
DomainS_TKc

MARK1 OBSCN LRRK1 MARK2 PRAG1 WNK2 PKN3

6.93e-04359777SM00220
DomainPkinase

MARK1 OBSCN LRRK1 MARK2 PRAG1 WNK2 PKN3

9.82e-04381777PF00069
DomainRoc

LRRK1 AGAP3

1.27e-0313772PF08477
DomainMIRO-like

LRRK1 AGAP3

1.27e-0313772IPR013684
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH1

1.48e-0314772IPR024317
DomainIRS_PTB

TLN1 IRS1

1.48e-0314772IPR002404
DomainDynein_HC_stalk

DNAH2 DNAH1

1.48e-0314772IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH1

1.48e-0314772IPR013602
DomainDHC_N2

DNAH2 DNAH1

1.48e-0314772PF08393
DomainMT

DNAH2 DNAH1

1.48e-0314772PF12777
DomainAAA_8

DNAH2 DNAH1

1.48e-0314772PF12780
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH1

1.48e-0314772IPR011704
DomainIRS

TLN1 IRS1

1.48e-0314772PF02174
DomainAAA_5

DNAH2 DNAH1

1.48e-0314772PF07728
DomainDHC_fam

DNAH2 DNAH1

1.70e-0315772IPR026983
DomainDynein_heavy_dom

DNAH2 DNAH1

1.70e-0315772IPR004273
DomainDynein_heavy

DNAH2 DNAH1

1.70e-0315772PF03028
Domain-

ATAD5 MTHFD1L DDX60 DNAH2 GNA15 LRRK1 GTPBP10 DNAH1 AGAP3

3.51e-037467793.40.50.300
DomainSer/Thr_kinase_AS

MARK1 OBSCN LRRK1 MARK2 WNK2 PKN3

3.55e-03357776IPR008271
DomainPROTEIN_KINASE_ST

MARK1 OBSCN LRRK1 MARK2 WNK2 PKN3

3.80e-03362776PS00108
DomainProt_kinase_dom

MARK1 OBSCN LRRK1 MARK2 PRAG1 WNK2 PKN3

4.01e-03489777IPR000719
DomainPROTEIN_KINASE_DOM

MARK1 OBSCN LRRK1 MARK2 PRAG1 WNK2 PKN3

4.19e-03493777PS50011
DomainUBA

MARK1 MARK2

6.77e-0330772SM00165
DomainKinase-like_dom

MARK1 OBSCN LRRK1 MARK2 PRAG1 WNK2 PKN3

6.96e-03542777IPR011009
DomainP-loop_NTPase

ATAD5 MTHFD1L DDX60 DNAH2 GNA15 LRRK1 GTPBP10 DNAH1 AGAP3

8.00e-03848779IPR027417
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

C2CD3 MTHFD1L TLN1 KIAA0319L OBSCN IRS1 LRRK1 PRAG1 BIRC6 WNK2 PKN3 PHC2 AGAP3

1.19e-061105791335748872
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

AP4E1 TMEM201 C2CD3 TBC1D31 MTHFD1L PKP4 TLN1 CNKSR3 KIAA0319L CPLANE1 FHIP2B

3.59e-06853791128718761
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

HDAC4 MARK1 IRS1 MARK2 PRAG1

3.73e-0610279515778465
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH17 DNAH2 DNAH1

4.03e-06147939373155
Pubmed

Structural variations in the catalytic and ubiquitin-associated domains of microtubule-associated protein/microtubule affinity regulating kinase (MARK) 1 and MARK2.

MARK1 MARK2

5.09e-06279216803889
Pubmed

ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.

AP4E1 TMEM201 MTHFD1L PKP4 USP32 KIAA0319L NUP133 UGT8 MARK2 BIRC6 ADD1

1.01e-05952791138569033
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

MARK1 PKP4 FBXO41 MARK2 ADD1 JPH3

1.49e-0523179616452087
Pubmed

MARK, a novel family of protein kinases that phosphorylate microtubule-associated proteins and trigger microtubule disruption.

MARK1 MARK2

1.53e-0537929108484
Pubmed

HIV/AIDS. Persistence by proliferation?

C2CD3 PKP4 KIAA0319L

2.82e-052679325013050
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

CREBRF TET2 NLN NRBF2 HDAC4 PKP4 USP32 MARK2

3.02e-0553679815840001
Pubmed

Phosphorylation of MAP2c and MAP4 by MARK kinases leads to the destabilization of microtubules in cells.

MARK1 MARK2

3.05e-05479210542369
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

CREBRF TET2 NLN NRBF2 HDAC4 PKP4 USP32 MARK2

3.10e-0553879810512203
Pubmed

The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition.

ACSL4 MARK1 MTHFD1L SRBD1 PKN3 PHC2

4.47e-0528179624163370
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

FKBP15 HDAC4 MARK1 PKP4 MARK2 BIRC6 AGAP3

7.12e-0544679724255178
Pubmed

Role of individual MARK isoforms in phosphorylation of tau at Ser²⁶² in Alzheimer's disease.

MARK1 MARK2

7.60e-05679223666762
Pubmed

New role for hPar-1 kinases EMK and C-TAK1 in regulating localization and activity of class IIa histone deacetylases.

HDAC4 MARK2

7.60e-05679216980613
Pubmed

Genetic mapping of a male germ cell-expressed gene Tpx-2 to mouse chromosome 17.

C3 DAZL

7.60e-0567921869307
Pubmed

Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly.

C2CD3 ZNHIT6 TBC1D31

8.99e-053879336674791
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH2 DNAH1

1.06e-0477929256245
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH17 DNAH2

1.06e-04779231178125
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

MEST ATXN7 ATAD5 MTHFD1L PKP4 TLN1 MARK2 SRBD1 GTPBP10 TFAP2C PHC2 AGAP3

1.37e-041497791231527615
Pubmed

Differential regulation of estrogen receptor α expression in breast cancer cells by metastasis-associated protein 1.

HDAC4 TFAP2C

1.41e-04879224413532
Pubmed

Systematic survey of deubiquitinase localization identifies USP21 as a regulator of centrosome- and microtubule-associated functions.

MARK1 MARK2

1.41e-04879222298430
Pubmed

Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice.

TET2 MEST DAZL

1.70e-044779332892421
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

ACSL4 ATAD5 TLN1 MARK2 ADD1 PHC2

2.01e-0437079622922362
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TET2 SLIT3 FBXO41 KDM7A LRRK1 SHOC2 WNK2

2.04e-0452979714621295
Pubmed

Dynein and kinesin regulate stress-granule and P-body dynamics.

DNAH2 DNAH1

2.27e-041079219825938
Pubmed

Csf2 null mutation alters placental gene expression and trophoblast glycogen cell and giant cell abundance in mice.

TLN1 IRS1 TFAP2C

2.57e-045479319228596
Pubmed

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci.

TET2 PTPN9 LCORL SLIT3

2.68e-0413679425429064
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

NRBF2 ATAD5 NUP133 MARK2 SRBD1 HSF2 BIRC6 GTPBP10

3.31e-0475979835915203
Pubmed

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant.

MARK1 MTHFD1L FBXO41 MARK2 JPH3 AGAP3

4.48e-0443079632581705
Pubmed

LKB1 is a master kinase that activates 13 kinases of the AMPK subfamily, including MARK/PAR-1.

MARK1 MARK2

5.25e-041579214976552
Pubmed

HIV latency. Specific HIV integration sites are linked to clonal expansion and persistence of infected cells.

PKP4 KIAA0319L

5.99e-041679224968937
Pubmed

Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS-Hook-FHIP complexes.

AP4E1 KIAA0319L FHIP2B

6.01e-047279334882091
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

ACSL4 PTPN9 C2CD3 TBC1D31 ATAD5 PKP4 NUP133 SHOC2 BIRC6

6.20e-04104979927880917
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

ACSL4 YEATS2 PTPN9 ATXN7 ATAD5 DNAH2 FHIP2B

6.26e-0463879731182584
Pubmed

Gene-trap mutagenesis using Mol/MSM-1 embryonic stem cells from MSM/Ms mice.

NLN USP32 MARK2

6.51e-047479323604909
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

C2CD3 TBC1D31 ATAD5 TLN1 C3 SRBD1 PHC2

6.68e-0464579725281560
Pubmed

Fgf and Esrrb integrate epigenetic and transcriptional networks that regulate self-renewal of trophoblast stem cells.

ATAD5 SRBD1 TFAP2C PHC2

7.24e-0417779426206133
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

TET2 C2CD3 HDAC4 CNKSR3 IRS1 MARK2 PRAG1 AGAP3

7.57e-0486179836931259
Pubmed

Proteomics analysis of protein kinases by target class-selective prefractionation and tandem mass spectrometry.

MARK1 MARK2 PKN3

7.59e-047879317192257
Pubmed

MORC2B is essential for meiotic progression and fertility.

MORC1 CFAP65

7.61e-041879229329290
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

PKP4 KIAA0319L NUP133 MARK2

7.70e-0418079435198878
Pubmed

Candidate gene/loci studies in cleft lip/palate and dental anomalies finds novel susceptibility genes for clefts.

MTHFD1L COL27A1 HSF2

7.88e-047979318978678
Pubmed

Additive effect of multiple genetic variants on the risk of coronary artery disease.

MTHFD1L IRS1

8.50e-041979220738937
Pubmed

Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.

ACSL4 HDAC4 TLN1 MARK2

9.42e-0419079415161933
Pubmed

Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms.

MARK1 MARK2

9.43e-042079218227155
Pubmed

Genome-wide diet-gene interaction analyses for risk of colorectal cancer.

MORC1 LCORL

1.04e-032179224743840
Pubmed

Hundreds of variants clustered in genomic loci and biological pathways affect human height.

TET2 LCORL ATAD5 SLIT3

1.10e-0319879420881960
Pubmed

Protein tyrosine phosphatase receptor delta acts as a neuroblastoma tumor suppressor by destabilizing the aurora kinase A oncogene.

IRS1 MARK2

1.14e-032279222305495
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

PKP4 FBXO41 MARK2 ADD1 JPH3

1.18e-0334779517114649
Pubmed

The Repeat Expansion Diseases: The dark side of DNA repair.

ATXN7 JPH3

1.25e-032379226002199
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

YEATS2 FKBP15 NRBF2 ATAD5 TLN1 NUP133 PKN3 ADD1

1.27e-0393479833916271
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

YEATS2 DDX60 COL27A1 TLN1

1.32e-0320879433230847
Pubmed

Analysis of HSF4 binding regions reveals its necessity for gene regulation during development and heat shock response in mouse lenses.

DDX60 HSF2

1.36e-032479218755693
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

ACSL4 MARK1 DNAH17 DNAH2 IRS1 MARK2 WNK2

1.37e-0373079734857952
Pubmed

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

MEST C2CD3 MARK1 PKP4 C3 MARK2 CPLANE1

1.39e-0373279734732716
Pubmed

Differential protein-protein interactions of LRRK1 and LRRK2 indicate roles in distinct cellular signaling pathways.

NUP133 LRRK1

1.48e-032579224947832
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

FKBP15 PTPN9 HDAC4 PKP4 CNKSR3 FBXO41 WNK2 ADD1

1.55e-0396379828671696
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

PKP4 FBXO41 SHOC2 PRAG1

1.56e-0321879433378226
Pubmed

Widespread and dynamic translational control of red blood cell development.

PKP4 BIRC6 SLC45A4

1.65e-0310279327899360
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

YEATS2 NLN BIRC6

1.69e-0310379310574462
Pubmed

Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

COL27A1 KIAA0319L LRRK1

1.89e-0310779311347906
Pubmed

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.

YEATS2 ATXN7 MARK2

1.89e-0310779320508642
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

YEATS2 HDAC4 ATXN7 OBSCN ARHGEF37 TECTA CFAP69 WNK2 DNAH1 AGAP3

1.97e-031489791028611215
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

ATXN7 DNAH2 WNK2 SLC45A4

1.99e-0323379437704626
Pubmed

Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function.

TET2 HDAC4

2.13e-033079221946350
Pubmed

14-3-3 cooperates with LKB1 to regulate the activity and localization of QSK and SIK.

MARK1 MARK2

2.13e-033079216306228
Pubmed

STK11 is required for the normal program of ciliated cell differentiation in airways.

MARK1 MARK2

2.27e-033179231636950
Cytoband7q21.13

ZNF804B CFAP69 GTPBP10

4.09e-0797937q21.13
GeneFamilyDyneins, axonemal

DNAH17 DNAH2 DNAH1

7.75e-0617423536
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#4_top-relative-expression-ranked_1000

CREBRF LCORL UGT8 DAZL BIRC6

4.96e-05107795gudmap_developingGonad_e16.5_ovary_1000_k4
CoexpressionAtlasDevelopingGonad_P2_ovary_emap-30224_top-relative-expression-ranked_500

MORC1 TDRD5 LRRC31 LCORL PKP4 DAZL CPLANE1 BIRC6

8.27e-05379798gudmap_developingGonad_P2_ovary_500
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_500

MORC1 TDRD5 LCORL PKP4 UGT8 DAZL CPLANE1 ADD1

9.56e-05387798gudmap_developingGonad_e16.5_ovary_500
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

MORC1 TDRD5 LRRC31 LCORL PKP4 UGT8 DAZL CPLANE1 BIRC6 ADD1 FHIP2B

1.39e-047787911gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#4_top-relative-expression-ranked_500

MORC1 TDRD5 DAZL ADD1

1.51e-0472794gudmap_developingGonad_e16.5_ovary_500_k4
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

MORC1 CREBRF TDRD5 LCORL PKP4 UGT8 DAZL CPLANE1 BIRC6 ADD1 FHIP2B

1.68e-047957911gudmap_developingGonad_e16.5_ovary_1000
ToppCellASK452-Epithelial-Secretory|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

AP4E1 YEATS2 SRBD1 WNK2 PKN3

3.81e-0613279549ba24e24b3127b5257a88a0ee0246c9843c580a
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

OBSCN NUP133 CPLANE1 CFAP69 SLC45A4

1.16e-0516679532d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACSL4 MEST PKP4 UGT8 SLC45A4

1.77e-0518179522363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellControl_saline-Epithelial_airway-airway_epithelial-Ciliated|Control_saline / Treatment groups by lineage, cell group, cell type

CFAP107 DNAH2 CFAP69 DNAH1 CFAP65

2.52e-0519579560067b5359174f0d1a8b5748bfc0690762e9e740
ToppCellControl_saline-Epithelial_airway|Control_saline / Treatment groups by lineage, cell group, cell type

CFAP107 DNAH2 C3 DNAH1 CFAP65

2.72e-05198795e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCellControl_saline-Epithelial_airway-airway_epithelial|Control_saline / Treatment groups by lineage, cell group, cell type

CFAP107 DNAH2 C3 DNAH1 CFAP65

2.72e-05198795e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CFAP107 DNAH2 C3 TFAP2C DNAH1

2.78e-0519979560919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCellLPS_anti-TNF-Epithelial_airway|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CFAP107 DNAH2 C3 TFAP2C DNAH1

2.78e-051997956aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CFAP107 DNAH2 TFAP2C WNK2 CFAP65

2.85e-05200795cf191104484bfb2b9f87de416b9453135f8833c1
ToppCellLPS_IL1RA-Epithelial_airway|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CFAP107 DNAH2 TFAP2C WNK2 CFAP65

2.85e-05200795a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
Diseasevisual impairment and progressive phthisis bulbi (implicated_via_orthology)

MARK1 MARK2

4.12e-054782DOID:0070356 (implicated_via_orthology)
Diseasearecaidine measurement

PYROXD2 SLIT3

6.86e-055782EFO_0801112
Diseaseanemia (phenotype), response to ribavirin

DNAH17 ZNF804B

2.45e-049782EFO_0004272, GO_1901559
Diseasecalcium measurement

TET2 HDAC4 LCORL PYROXD2 DNAH2 UGT8 PKN3 FHIP2B

2.55e-04628788EFO_0004838
Diseasecreatinine measurement

TET2 AP4E1 PTPN9 ATXN7 FAAP24 USP32 OBSCN MRPL36 BIRC6 PHC2

2.87e-049957810EFO_0004518
Diseaseaspartate aminotransferase measurement

CNKSR3 PYROXD2 OBSCN DNAH2 SHOC2 PRAG1 BIRC6 WNK2 SLC45A4

6.29e-04904789EFO_0004736
Diseaseosteoarthritis, knee

COL27A1 CNKSR3 PRAG1 SLC45A4

8.30e-04158784EFO_0004616
Diseaseperitonsillar abscess

TET2 PRAG1

1.03e-0318782EFO_0007429
Diseasediet measurement, colorectal cancer

MORC1 LCORL

1.15e-0319782EFO_0008111, MONDO_0005575
Diseasepulmonary embolism

DNAH17 CNKSR3

1.99e-0325782EFO_0003827
Diseaseamino acid measurement

HDAC4 SLIT3 MRPL36 LRRK1 SHOC2 WNK2 PHC2

2.11e-03678787EFO_0005134
Diseasecorpus callosum volume measurement

TLN1 WNK2 ADD1

2.39e-03100783EFO_0010299

Protein segments in the cluster

PeptideGeneStartEntry
KNVGGIPALLRLLRK

PKP4

611

Q99569
KAILQFQKLCGLKPL

TDRD5

606

Q8NAT2
NLLLFKKVKALLGGN

ACSL4

421

O60488
AIPIKQGILLKRSGK

AGAP3

366

Q96P47
GLPDLLKRQIAKKAA

ATAD5

841

Q96QE3
KLDKIGLNLPAGRRK

TFAP2C

281

Q92754
QVTLLKNKAPGLGKV

BIRC6

1121

Q9NR09
GIKVKLLRGLLPNLV

BPIFB4

301

P59827
AKALLGPQNLIKKRL

ARHGEF37

351

A1IGU5
GPQNLIKKRLDKLLD

ARHGEF37

356

A1IGU5
NPKKLLQIGNELRKL

CREBRF

491

Q8IUR6
RLKGPLLNKFLTTAK

C3

1201

P01024
QLARLKKLGINKTDP

MTHFD1L

536

Q6UB35
LSPKINLKYLGLKAL

AP4E1

346

Q9UPM8
VLNLLKGAFPARLKK

PTPN9

171

P43378
RIKLALLLQKLQLGG

MORC1

921

Q86VD1
LEKGKRGKLLSQPIS

NUP133

906

Q8WUM0
AKQRLGKILKLNRNG

KDM7A

921

Q6ZMT4
NPLNRQKLDSKKLLG

HDAC4

726

P56524
QIAKKLSKGIRPVLG

LRRK1

1471

Q38SD2
LKPTSRAGIKQKGLL

KIAA0319L

981

Q8IZA0
PLLLRGKSVQKKQAE

CFAP65

31

Q6ZU64
LEGSALQKLKNILPK

LCORL

446

Q8N3X6
KIGKLIKSNVPELRG

DDX60

1346

Q8IY21
KLKVQALKDRGLSIP

LSM1

111

O15116
GKLLLVRKQLTGQAP

FHIP2B

681

Q86V87
LFKGATLKALRPKAQ

FKBP15

1171

Q5T1M5
NLPLILQKFQKGSKI

LRRC31

186

Q6UY01
KKQDRGELKLLLLGP

GNA15

36

P30679
VILKPKGLGQTKNLI

IRS1

166

P35568
LLKSPKEKLQLRGNT

ATXN7

221

O15265
NKQLKAEKARLLKGP

NRBF2

196

Q96F24
LAVQGNLLRKLPRKT

OBSCN

416

Q5VST9
KKVLLKAGLQNLPIT

DNAH1

2626

Q9P2D7
KLLTNFLPLKGQKRI

GTPBP10

126

A4D1E9
KVRSPGQDKLLGLVK

C2CD3

886

Q4AC94
QSVILSKPKGKGLNL

CPLANE1

451

Q9H799
VLDPLLGRNTIKKGK

DNAH17

3496

Q9UFH2
SKNPLLGKKRALLLS

FAAP24

141

Q9BTP7
NKLAGALGRLPQKVI

UGT8

306

Q16880
LKQRQLTPKAGLKQS

CFAP107

146

Q8N1D5
QGINLKLLPNGFTKR

ZNHIT6

316

Q9NWK9
KRKLQLGLQFLPGKT

COL27A1

121

Q8IZC6
SLTLQNLKPRQRGKK

FBXO41

616

Q8TF61
NLLKKLLVLNPIKRG

MARK1

286

Q9P0L2
LKKFLILNPSKRGTL

MARK2

281

Q7KZI7
KKLKLGPAIRKQNLC

DAZL

106

Q92904
IALKKLPIRGGALQR

CFAP69

911

A5D8W1
IKLLRIQKVGGPSSK

DNAH2

1566

Q9P225
RPLLLQKLLKDGGVL

MEST

186

Q5EB52
QKLLQKCPEKRLGAG

PKN3

791

Q6P5Z2
RKRPLLLNTNGAQKK

HSF2

196

Q03933
LPALGFKNKTVLKKR

MRPL36

61

Q9P0J6
LPDGLNKKRLQILLK

TBC1D31

406

Q96DN5
RLLPGEKAQKLLQKV

ENTPD6

186

O75354
KPGIKRATIKGQIQL

SPATA32

326

Q96LK8
LLKKLPHGLGNLRKL

SHOC2

436

Q9UQ13
PFINREQLKKVKGLG

SRBD1

741

Q8N5C6
IQKNLGPKSKVLILR

ADD1

286

P35611
LKNLVKKLRENPTGV

CNK3/IPCEF1

271

G9CGD6
LKNLVKKLRENPTGV

CNKSR3

271

Q6P9H4
QQLLPLRTKVAKLLG

NLN

281

Q9BYT8
KPTVLKLTRKEGLQG

SLC45A4

746

Q5BKX6
GIFKKLPNLRKINLS

SLIT3

551

O75094
RLYLPLKLGQGKINI

TECTA

1186

O75443
PVGRSSLLVGNLKKK

PHC2

586

Q8IXK0
LLLKGKNLPRIISDK

ZNF804B

166

A4D1E1
TLKPLLKAGRILGAQ

PYROXD2

201

Q8N2H3
GKNKLVPRLLGITKE

TLN1

321

Q9Y490
PLLRLANQLKKGGLY

SLC12A9

546

Q9BXP2
RPGKLNAQKLKDLGV

ELAC1

196

Q9H777
ARLNLKGQKLLLFPS

TMEM201

531

Q5SNT2
RLIISNFLKAKQKPG

PRAG1

1211

Q86YV5
TGRLTNFKIPLLKNK

TOPAZ1

681

Q8N9V7
GKNLGLKSSLIRKPR

ZNF879

161

B4DU55
LQGKRSKLLKQGDSP

ZNF233

126

A6NK53
LKAGKLLNPLVRQLK

WNK2

1991

Q9Y3S1
PSLSGLLQIKKLKQD

TET2

101

Q6N021
KGRLRLPQIGSKNKL

USP32

1406

Q8NFA0
KGKLLLIPQGAILRA

YEATS2

771

Q9ULM3
NILVGGKRKNLIPLR

JPH3

341

Q8WXH2