Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnicotinic acid receptor activity

HCAR3 HCAR2

6.91e-062532GO:0070553
GeneOntologyBiologicalProcesspositive regulation of adiponectin secretion

HCAR3 HCAR2

3.44e-054502GO:0070165
GeneOntologyCellularComponentDNA-dependent protein kinase complex

ZBTB7A PRKDC

6.04e-055522GO:0070418
DomainHCAR2/3_rcpt

HCAR3 HCAR2

7.60e-062522IPR028017
DomainPP2A_B56

PPP2R5D PPP2R5E

7.56e-055522IPR002554
DomainB56

PPP2R5D PPP2R5E

7.56e-055522PF01603
Domain-

TRAF3 PHF20 KDM5A RCHY1 MTMR3 ARIH1 PHF13

2.33e-044495273.30.40.10
DomainZnf_RING/FYVE/PHD

TRAF3 PHF20 KDM5A RCHY1 MTMR3 ARIH1 PHF13

2.66e-04459527IPR013083
DomainZnf_FYVE_PHD

PHF20 KDM5A MTMR3 PHF13

7.44e-04147524IPR011011
DomainPHD

PHF20 KDM5A PHF13

1.19e-0375523PF00628
DomainZnf_PHD-finger

PHF20 KDM5A PHF13

1.39e-0379523IPR019787
DomainBTB

ZBTB7A KBTBD6 KCNG3 ZBTB11

1.57e-03180524SM00225
DomainBTB/POZ_dom

ZBTB7A KBTBD6 KCNG3 ZBTB11

1.74e-03185524IPR000210
DomainSKP1/BTB/POZ

ZBTB7A KBTBD6 KCNG3 ZBTB11

1.88e-03189524IPR011333
DomainPHD

PHF20 KDM5A PHF13

1.95e-0389523SM00249
DomainZnf_PHD

PHF20 KDM5A PHF13

2.08e-0391523IPR001965
DomainZF_PHD_2

PHF20 KDM5A PHF13

2.35e-0395523PS50016
DomainZF_PHD_1

PHF20 KDM5A PHF13

2.42e-0396523PS01359
DomainHECT

HACE1 HERC6

2.55e-0327522PF00632
DomainHECTc

HACE1 HERC6

2.55e-0327522SM00119
DomainHECT_dom

HACE1 HERC6

2.55e-0327522IPR000569
DomainHECT

HACE1 HERC6

2.55e-0327522PS50237
DomainBTB

ZBTB7A KBTBD6 ZBTB11

5.80e-03131523PF00651
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

NPC1 GLIPR1 ZNF836 FRY PPP2R5E KDM5A CEP290 HECTD4 MTMR3 TTC27 MIGA1 PRKDC HARS1 ZBTB11

5.14e-091285531435914814
Pubmed

Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.

PPP2R5D PPP2R5E PRKDC

7.28e-071253316541024
Pubmed

Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization.

HCAR3 HCAR2

2.28e-06253228186140
Pubmed

The Immunometabolomic Interface Receptor Hydroxycarboxylic Acid Receptor 2 Mediates the Therapeutic Effects of Dimethyl Fumarate in Autoantibody-Induced Skin Inflammation.

HCAR3 HCAR2

2.28e-06253230154797
Pubmed

The niacin/butyrate receptor GPR109A suppresses mammary tumorigenesis by inhibiting cell survival.

HCAR3 HCAR2

2.28e-06253224371223
Pubmed

High dietary niacin may increase prostaglandin formation but does not increase tumor formation in ApcMin/+ mice.

HCAR3 HCAR2

2.28e-06253221774590
Pubmed

The role of HCA2 (GPR109A) in regulating macrophage function.

HCAR3 HCAR2

2.28e-06253223882124
Pubmed

Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model.

HCAR3 HCAR2

2.28e-06253236891315
Pubmed

GPR109a Regulates Phenotypic and Functional Alterations in Macrophages and the Progression of Type 1 Diabetes.

HCAR3 HCAR2

2.28e-06253236208084
Pubmed

Parabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a.

HCAR3 HCAR2

2.28e-06253238007572
Pubmed

The role of the C-terminus of the human hydroxycarboxylic acid receptors 2 and 3 in G protein activation using Gα-engineered yeast cells.

HCAR3 HCAR2

2.28e-06253226656756
Pubmed

Biased allosteric activation of ketone body receptor HCAR2 suppresses inflammation.

HCAR3 HCAR2

2.28e-06253237597514
Pubmed

The Role of GPR109a Signaling in Niacin Induced Effects on Fed and Fasted Hepatic Metabolism.

HCAR3 HCAR2

2.28e-06253233924461
Pubmed

Hydroxycarboxylic acid receptor 2 mediates dimethyl fumarate's protective effect in EAE.

HCAR3 HCAR2

2.28e-06253224691444
Pubmed

Ketone Body 3-Hydroxybutyrate Ameliorates Atherosclerosis via Receptor Gpr109a-Mediated Calcium Influx.

HCAR3 HCAR2

2.28e-06253233977048
Pubmed

Butyrate ameliorates caerulein-induced acute pancreatitis and associated intestinal injury by tissue-specific mechanisms.

HCAR3 HCAR2

2.28e-06253231347703
Pubmed

PUMA-G, an IFN-gamma-inducible gene in macrophages is a novel member of the seven transmembrane spanning receptor superfamily.

HCAR3 HCAR2

2.28e-06253211745392
Pubmed

Loss of GPR109A/HCAR2 induces aging-associated hepatic steatosis.

HCAR3 HCAR2

2.28e-06253230659164
Pubmed

Niacin-induced hyperglycemia is partially mediated via niacin receptor GPR109a in pancreatic islets.

HCAR3 HCAR2

2.28e-06253225622782
Pubmed

GPR109A mediates the effects of hippuric acid on regulating osteoclastogenesis and bone resorption in mice.

HCAR3 HCAR2

2.28e-06253233420329
Pubmed

Expression and localization of GPR109A (PUMA-G/HM74A) mRNA and protein in mammalian retinal pigment epithelium.

HCAR3 HCAR2

2.28e-06253219223991
Pubmed

Molecular identification of nicotinic acid receptor.

HCAR3 HCAR2

2.28e-06253212646212
Pubmed

PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect.

HCAR3 HCAR2

2.28e-06253212563315
Pubmed

Niacin increases adiponectin and decreases adipose tissue inflammation in high fat diet-fed mice.

HCAR3 HCAR2

2.28e-06253223967184
Pubmed

Involvement of the Niacin Receptor GPR109a in the LocalControl of Glucose Uptake in Small Intestine of Type 2Diabetic Mice.

HCAR3 HCAR2

2.28e-06253226371038
Pubmed

Alloreactive T cells deficient of the short-chain fatty acid receptor GPR109A induce less graft-versus-host disease.

HCAR3 HCAR2

2.28e-06253234653248
Pubmed

Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G).

HCAR3 HCAR2

2.28e-06253219136666
Pubmed

G Protein-Coupled Receptor 109A Maintains the Intestinal Integrity and Protects Against ETEC Mucosal Infection by Promoting IgA Secretion.

HCAR3 HCAR2

2.28e-06253233488584
Pubmed

Lactate-induced activation of HCA2 improves survival in mice with sepsis.

HCAR3 HCAR2

2.28e-06253230951370
Pubmed

Niacin Ameliorates Hepatic Steatosis by Inhibiting De Novo Lipogenesis Via a GPR109A-Mediated PKC-ERK1/2-AMPK Signaling Pathway in C57BL/6 Mice Fed a High-Fat Diet.

HCAR3 HCAR2

2.28e-06253231858105
Pubmed

Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock.

HCAR3 HCAR2

2.28e-06253230625381
Pubmed

Exploring the role of the metabolite-sensing receptor GPR109a in diabetic nephropathy.

HCAR3 HCAR2

2.28e-06253232068460
Pubmed

The activation of retinal HCA2 receptors by systemic beta-hydroxybutyrate inhibits diabetic retinal damage through reduction of endoplasmic reticulum stress and the NLRP3 inflammasome.

HCAR3 HCAR2

2.28e-06253230657794
Pubmed

Ketones and pain: unexplored role of hydroxyl carboxylic acid receptor type 2 in the pathophysiology of neuropathic pain.

HCAR3 HCAR2

2.28e-06253230085883
Pubmed

Nicotinic acid receptor abnormalities in human skin cancer: implications for a role in epidermal differentiation.

HCAR3 HCAR2

2.28e-06253221655214
Pubmed

Melatonin alleviates titanium nanoparticles induced osteolysis via activation of butyrate/GPR109A signaling pathway.

HCAR3 HCAR2

2.28e-06253234092246
Pubmed

(D)-beta-Hydroxybutyrate inhibits adipocyte lipolysis via the nicotinic acid receptor PUMA-G.

HCAR3 HCAR2

2.28e-06253215929991
Pubmed

Activation of HCA2 regulates microglial responses to alleviate neurodegeneration in LPS-induced in vivo and in vitro models.

HCAR3 HCAR2

2.28e-06253236991440
Pubmed

Inflammation stimulates niacin receptor (GPR109A/HCA2) expression in adipose tissue and macrophages.

HCAR3 HCAR2

2.28e-06253225320346
Pubmed

Molecular identification of high and low affinity receptors for nicotinic acid.

HCAR3 HCAR2

2.28e-06253212522134
Pubmed

Nicotinic acid inhibits glucose-stimulated insulin secretion via the G protein-coupled receptor PUMA-G in murine islet β cells.

HCAR3 HCAR2

2.28e-06253221441844
Pubmed

G Protein-Coupled Receptor 109A and Host Microbiota Modulate Intestinal Epithelial Integrity During Sepsis.

HCAR3 HCAR2

2.28e-06253230271409
Pubmed

Niacin fine-tunes energy homeostasis through canonical GPR109A signaling.

HCAR3 HCAR2

2.28e-06253230596513
Pubmed

The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease.

HCAR3 HCAR2

2.28e-06253235320002
Pubmed

GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing.

HCAR3 HCAR2

2.28e-06253216322797
Pubmed

BHBA treatment improves cognitive function by targeting pleiotropic mechanisms in transgenic mouse model of Alzheimer's disease.

HCAR3 HCAR2

2.28e-06253231914599
Pubmed

Nicotinic acid receptor agonists.

HCAR3 HCAR2

2.28e-06253218983141
Pubmed

Gut microbial metabolite butyrate protects against proteinuric kidney disease through epigenetic- and GPR109a-mediated mechanisms.

HCAR3 HCAR2

2.28e-06253231366236
Pubmed

Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes.

HCAR3 HCAR2

2.28e-06253220655299
Pubmed

Evidence for constitutive dimerization of niacin receptor subtypes.

HCAR3 HCAR2

2.28e-06253220380810
Pubmed

GPR109A Expression in the Murine Min6 Pancreatic Beta Cell Line, and Its Relation with Glucose Metabolism and Inflammation.

HCAR3 HCAR2

2.28e-06253226116596
Pubmed

Expression and activation of the ketone body receptor HCAR2/GPR109A promotes preservation of retinal endothelial cell barrier function.

HCAR3 HCAR2

2.28e-06253235649469
Pubmed

GPR109A expressed on medullary thymic epithelial cells affects thymic Treg development.

HCAR3 HCAR2

2.28e-06253237595951
Pubmed

The hypophagic response to heat stress is not mediated by GPR109A or peripheral β-OH butyrate.

HCAR3 HCAR2

2.28e-06253226936786
Pubmed

Hydroxycarboxylic Acid Receptor 2, a Pleiotropically Linked Receptor for the Multiple Sclerosis Drug, Monomethyl Fumarate. Possible Implications for the Inflammatory Response.

HCAR3 HCAR2

2.28e-06253234084164
Pubmed

GPR109A gene deletion ameliorates gonadectomy-induced bone loss in mice.

HCAR3 HCAR2

2.28e-06253235489706
Pubmed

Deorphanization of GPR109B as a receptor for the beta-oxidation intermediate 3-OH-octanoic acid and its role in the regulation of lipolysis.

HCAR3 HCAR2

2.28e-06253219561068
Pubmed

Hyperhomocysteinemia is detrimental to pregnancy in mice and is associated with preterm birth.

HCAR3 HCAR2

6.83e-06353223579073
Pubmed

Short-chain fatty acids directly exert anti-inflammatory responses in podocytes and tubular epithelial cells exposed to high glucose.

HCAR3 HCAR2

6.83e-06353237215085
Pubmed

Colonic gene expression in conventional and germ-free mice with a focus on the butyrate receptor GPR109A and the butyrate transporter SLC5A8.

HCAR3 HCAR2

6.83e-06353220033346
Pubmed

Niacin stimulates adiponectin secretion through the GPR109A receptor.

HCAR3 HCAR2

6.83e-06353219141678
Pubmed

International Union of Basic and Clinical Pharmacology. LXXXII: Nomenclature and Classification of Hydroxy-carboxylic Acid Receptors (GPR81, GPR109A, and GPR109B).

HCAR3 HCAR2

6.83e-06353221454438
Pubmed

Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice.

HCAR3 HCAR2

6.83e-06353220664170
Pubmed

HACE1 Negatively Regulates Virus-Triggered Type I IFN Signaling by Impeding the Formation of the MAVS-TRAF3 Complex.

TRAF3 HACE1

6.83e-06353227213432
Pubmed

Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation.

HCAR3 HCAR2

6.83e-06353224226773
Pubmed

Activation of microglial GPR109A alleviates thermal hyperalgesia in female lupus mice by suppressing IL-18 and glutamatergic synaptic activity.

HCAR3 HCAR2

6.83e-06353234919284
Pubmed

Induction of the cystine/glutamate exchanger SLC7A11 in retinal pigment epithelial cells by the antipsoriatic drug monomethylfumarate.

HCAR3 HCAR2

6.83e-06353223404113
Pubmed

Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells.

HCAR3 HCAR2

6.83e-06353227570060
Pubmed

The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages.

HCAR3 HCAR2

6.83e-06353224845831
Pubmed

Oral Dimethyl Fumarate Targets HCA2-Expressing Skin Cells in the Imiquimod Mouse Model.

HCAR3 HCAR2

6.83e-06353235189149
Pubmed

The Butyrate-Producing Bacterium Clostridium butyricum Suppresses Clostridioides difficile Infection via Neutrophil- and Antimicrobial Cytokine-Dependent but GPR43/109a-Independent Mechanisms.

HCAR3 HCAR2

6.83e-06353233597149
Pubmed

Nicotinic acid-induced flushing is mediated by activation of epidermal langerhans cells.

HCAR3 HCAR2

6.83e-06353217008386
Pubmed

Effects of high fat diet on GPR109A and GPR81 gene expression.

HCAR3 HCAR2

6.83e-06353222842580
Pubmed

Niacin lipid efficacy is independent of both the niacin receptor GPR109A and free fatty acid suppression.

HCAR3 HCAR2

6.83e-06353222914621
Pubmed

Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide.

HCAR3 HCAR2

6.83e-06353231710686
Pubmed

Deficiency of Prebiotic Fiber and Insufficient Signaling Through Gut Metabolite-Sensing Receptors Leads to Cardiovascular Disease.

HCAR3 HCAR2

6.83e-06353232093510
Pubmed

Rare and potentially pathogenic variants in hydroxycarboxylic acid receptor genes identified in breast cancer cases.

HCAR3 HCAR2

6.83e-06353234852802
Pubmed

Dietary Fiber Protects against Diabetic Nephropathy through Short-Chain Fatty Acid-Mediated Activation of G Protein-Coupled Receptors GPR43 and GPR109A.

HCAR3 HCAR2

6.83e-06353232358041
Pubmed

Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells.

HCAR3 HCAR2

6.83e-06353221317532
Pubmed

Inefficient double-strand break repair in murine rod photoreceptors with inverted heterochromatin organization.

PRKDC PHF13

6.83e-06353224794298
Pubmed

Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammation.

CCR5 PRKDC

1.36e-05453222392992
Pubmed

Dietary Fiber and Bacterial SCFA Enhance Oral Tolerance and Protect against Food Allergy through Diverse Cellular Pathways.

HCAR3 HCAR2

1.36e-05453227332875
Pubmed

Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation.

HCAR3 HCAR2

1.36e-05453229514953
Pubmed

Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis.

HCAR3 HCAR2

1.36e-05453224412617
Pubmed

The ketone metabolite β-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.

HCAR3 HCAR2

1.36e-05453225686106
Pubmed

Clostridium butyricum upregulates GPR109A/AMPK/PGC-1α and ameliorates acute pancreatitis-associated intestinal barrier injury in mice.

HCAR3 HCAR2

1.36e-05453238761195
Pubmed

Niacin activates the PI3K/Akt cascade via PKC- and EGFR-transactivation-dependent pathways through hydroxyl-carboxylic acid receptor 2.

HCAR3 HCAR2

1.36e-05453225375133
Pubmed

Peroxisome proliferator-activated receptor gamma regulates expression of the anti-lipolytic G-protein-coupled receptor 81 (GPR81/Gpr81).

HCAR3 HCAR2

1.36e-05453219633298
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

HACE1 HECTD4 ARIH1 HERC6

1.38e-059553429643511
Pubmed

Assignment of human protein phosphatase 2A regulatory subunit genes b56alpha, b56beta, b56gamma, b56delta, and b56epsilon (PPP2R5A-PPP2R5E), highly expressed in muscle and brain, to chromosome regions 1q41, 11q12, 3p21, 6p21.1, and 7p11.2 --> p12.

PPP2R5D PPP2R5E

2.27e-0555328812429
Pubmed

Metabolite-sensing receptors GPR43 and GPR109A facilitate dietary fibre-induced gut homeostasis through regulation of the inflammasome.

HCAR3 HCAR2

2.27e-05553225828455
Pubmed

Genomic organisation, chromosomal localisation tissue distribution and developmental regulation of the PR61/B' regulatory subunits of protein phosphatase 2A in mice.

PPP2R5D PPP2R5E

2.27e-05553215095873
Pubmed

GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy.

HCAR3 HCAR2

2.27e-05553222427566
Pubmed

Lactate inhibits lipolysis in fat cells through activation of an orphan G-protein-coupled receptor, GPR81.

HCAR3 HCAR2

2.27e-05553219047060
Pubmed

β-Hydroxybutyrate suppresses colorectal cancer.

HCAR3 HCAR2

2.27e-05553235477756
Pubmed

Two complex genotypes relevant to the kynurenine pathway and melanotropin function show association with schizophrenia and bipolar disorder.

HCAR3 HCAR2

3.40e-05653219502010
Pubmed

Chlamydia pneumoniae Hijacks a Host Autoregulatory IL-1β Loop to Drive Foam Cell Formation and Accelerate Atherosclerosis.

HCAR3 HCAR2

3.40e-05653229937375
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

MYO1B SAMHD1 PRKDC RFC5

3.46e-0512053427320910
Pubmed

The B56 family of protein phosphatase 2A (PP2A) regulatory subunits encodes differentiation-induced phosphoproteins that target PP2A to both nucleus and cytoplasm.

PPP2R5D PPP2R5E

4.76e-0575328703017
Pubmed

Intestinal microbiota-derived short-chain fatty acids regulation of immune cell IL-22 production and gut immunity.

HCAR3 HCAR2

4.76e-05753232901017
CytobandEnsembl 112 genes in cytogenetic band chr12q24

HCAR3 HCAR2 HECTD4 RFC5

1.36e-03415534chr12q24
GeneFamilyHydroxy-carboxylic acid receptors

HCAR3 HCAR2

1.22e-053372200
GeneFamilyWD repeat domain containing|Protein phosphatase 2 regulatory subunits

PPP2R5D PPP2R5E

4.21e-0415372696
GeneFamilyPHD finger proteins

PHF20 KDM5A PHF13

8.20e-049037388
GeneFamilyBasic leucine zipper proteins|BTB domain containing

ZBTB7A KBTBD6 ZBTB11

2.57e-03134373861
CoexpressionGSE339_CD4POS_VS_CD8POS_DC_UP

NPC1 TRAF3 PPP2R5D MYO1B SAMHD1

5.24e-05200535M5108
CoexpressionGSE13493_DP_VS_CD8POS_THYMOCYTE_DN

ADGRG3 TTC27 PRKDC IDH3A RFC5

5.24e-05200535M3315
CoexpressionGSE2770_IL12_ACT_VS_ACT_CD4_TCELL_2H_DN

NPC1 TRAF3 MYO1B CCR5 PHF13

5.24e-05200535M6127
CoexpressionGSE8621_UNSTIM_VS_LPS_PRIMED_UNSTIM_MACROPHAGE_DN

TRAF3 PPP2R5E ASTE1 PPIP5K1 PRKDC

5.24e-05200535M6980
CoexpressionBLANCO_MELO_HUMAN_PARAINFLUENZA_VIRUS_3_INFECTION_A594_CELLS_UP

GLIPR1 HCAR3 HCAR2 SAMHD1 HERC6

5.76e-05204535M34006
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GLIPR1 CLEC4E HCAR2 MED12L SAMHD1

9.40e-071495352a2a5673ce4f376e7b25f2bc8127fb7e260f37af
ToppCellPND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GLIPR1 CLEC4E HCAR2 MED12L SAMHD1

9.40e-07149535c9f02ec62a658a751e591699f9395fe597e22a2e
ToppCell10x5'v1-week_12-13-Myeloid_DC-DC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GLIPR1 CCDC88A CCR5 SAMHD1 IDH3A

2.95e-061885356b0e0192519ea3ca49fb21de3da9a0a108fcb64d
ToppCell10x5'v1-week_12-13-Myeloid_DC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

GLIPR1 CCDC88A CCR5 SAMHD1 IDH3A

2.95e-061885350b19c35fdc2b9e064e8f03ef69ae08644794ec24
ToppCell10x5'v1-week_14-16-Myeloid_DC-DC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GLIPR1 CCDC88A CCR5 SAMHD1 IDH3A

3.10e-06190535d06800ec9f6065c1cc536ed99e8569732272a94f
ToppCell10x5'v1-week_14-16-Myeloid_DC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GLIPR1 CCDC88A CCR5 SAMHD1 IDH3A

3.10e-06190535485073e831afebdb393c7f4b622504d43d1b778b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GLIPR1 ANKRD44 CLEC4E SAMHD1 ARHGAP45

3.18e-0619153547a2afc4102199b4bc76bd01b2967c8016186462
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Granulocytic-Neutrophil|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GLIPR1 HCAR3 CLEC4E HCAR2 SAMHD1

3.26e-06192535e2fa1ba26d28953f0d35d95764b5dbe0b93a1191
ToppCellkidney_cells-Adult_normal_reference-Immune-Myeloid-Granulocytic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GLIPR1 HCAR3 CLEC4E HCAR2 SAMHD1

3.26e-06192535161f4626571b1bce5758fad1fe5ce41a4621771d
ToppCellCOVID-19-kidney-Myeloid|COVID-19 / Disease (COVID-19 only), tissue and cell type

ANKRD44 HCAR3 CLEC4E HCAR2 ADGRG3

3.26e-061925350b9d22a222f1201e375f8e55cace9ef939febae4
ToppCell10x3'2.3-week_14-16-Myeloid_DC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GLIPR1 CCDC88A CCR5 SAMHD1 IDH3A

3.35e-06193535c6633aca0eb4d699c4d3da3199b84bebd87e2d31
ToppCell10x5'v1-week_17-19-Myeloid_DC-DC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GLIPR1 CCDC88A CCR5 SAMHD1 IDH3A

3.35e-06193535bdbbfcbe339f23a88dfcc59d53c034bac1605b07
ToppCell10x5'v1-week_17-19-Myeloid_DC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GLIPR1 CCDC88A CCR5 SAMHD1 IDH3A

3.35e-06193535acafe177cd05b2966f5fa26ea02f420f13f2cee5
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GLIPR1 CCDC88A CCR5 SAMHD1 IDH3A

3.35e-06193535a32791b4bdb7c5f2b4cc75b660321ab75c4fac9b
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Monocytes|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

GLIPR1 HCAR3 CLEC4E HCAR2 SAMHD1

3.35e-06193535ddbd8944661ac3b0b5fe63471bdc24ba05598017
ToppCellCF-Myeloid|CF / Disease state, Lineage and Cell class

HCAR3 CLEC4E HCAR2 FRY ADGRG3

3.52e-06195535ecf604de496f389a49429d0bb211e1db6019cc8b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic-Neutrophil|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GLIPR1 HCAR3 CLEC4E HCAR2 SAMHD1

3.52e-06195535d8d2467196d7b2ce0c2cf6782e03e6db141ed3bf
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLIPR1 HCAR3 CLEC4E HCAR2 SAMHD1

3.52e-06195535391d8e00dd5f988baa6dbda8414d3c020679ea2f
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Granulocytic|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

GLIPR1 HCAR3 CLEC4E HCAR2 SAMHD1

3.52e-0619553568b579258caf023570c3922269e831e27d847934
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLIPR1 ANKRD44 CCDC88A SAMHD1 ARHGAP45

3.61e-06196535291c59b609985167c98a40d4e2caeea2fad74941
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

GLIPR1 CLEC4E HCAR2 ADGRG3 SAMHD1

3.61e-06196535f811958823380069077754283e36106d80147494
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic-Monocyte-derived_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLIPR1 ANKRD44 CCDC88A SAMHD1 ARHGAP45

3.70e-06197535826cc6baafab13e7ef5cfcf28cd79d0fbf3af38d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLIPR1 HCAR3 CLEC4E HCAR2 SAMHD1

3.70e-06197535c34d0d11c5c6154988b41e00aea169090cb09785
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HCAR3 CLEC4E HCAR2 ADGRG3

2.27e-05139534fa0eedebf53317928022c3bed391ce99a2114f98
ToppCellfacs-Aorta-Heart-24m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E HCAR2 ARHGAP45

2.75e-05146534d8d24851e8d8d90795a6f9378418f209200d55b1
ToppCellfacs-Aorta-Heart-24m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 HCAR2 CCR5 ARHGAP45

3.84e-05159534443f6df4a88fa8755adcde4cc12575dff614ecb4
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Myeloid-cardiac_mast_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E HCAR2 ARHGAP45

3.84e-05159534766dfb9f9c0783e740a4fd395e99669310b33371
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CHST10 HCAR2 SAMHD1

3.84e-05159534f7803f7b4e0379ae8256ec53110833bedee7db98
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CHST10 HCAR2 SAMHD1

3.84e-051595346e2d38e78d2ef7803e8bb154b5c788bf62a41045
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

GLIPR1 ADGRG3 CCR5 ARHGAP45

3.94e-051605344a0ae0a83a10dbfc13591f4d2228ba8bcd2c2275
ToppCellPCW_13-14-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

HCAR3 CLEC4E HCAR2 ADGRG3

3.94e-0516053408696d93ff42a1beca23c70ab3e0d082cfff4aa7
ToppCellDendritic_Cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

GLIPR1 ANKRD44 CLEC4E ARHGAP45

4.55e-05166534fbeb74b98b58085de323f744b18d4a8f7b22d5d4
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Lymphocytic-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E RFC5 ARHGAP45

4.65e-0516753441675d15919104c9e20cd97620fe636f3ff33fa9
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Lymphocytic|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E RFC5 ARHGAP45

4.65e-051675343d5a6a4c7d037b1a6a8ec90034d88ef6d256e843
ToppCelldroplet-Bladder-nan-24m-Hematologic-granulocyte-monocyte_progenitor|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E CCR5 ARHGAP45

4.76e-05168534c6e0daa790dd5db20dd1ab8c1e7142484976d743
ToppCellsevere_COVID-19-Neutrophil|World / disease group, cell group and cell class (v2)

HCAR3 CLEC4E HCAR2 ADGRG3

4.99e-05170534dfc807e0dd66179490a258ecbe8eb439e715799d
ToppCellMonocytes-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

GLIPR1 ANKRD44 SAMHD1 ARHGAP45

4.99e-051705344e93b66b3033e6e4d5f6d2f41974623a53108f5e
ToppCelldroplet-Trachea-nan-3m-Myeloid-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E CCR5 ARHGAP45

5.10e-05171534ca88f17e4ca28be544bad2c8fa3d2733cc6408d2
ToppCelldroplet-Trachea-3m-Hematologic-myeloid|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GLIPR1 CLEC4E CCR5 ARHGAP45

5.10e-05171534a95400078e3cfd69b384061ffe6b6bfc93b9ca6d
ToppCelldroplet-Trachea-nan-3m-Myeloid|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E CCR5 ARHGAP45

5.10e-051715342b3b0ca2ebceb287e1b0ea48a13838912dd9f9d7
ToppCelldroplet-Trachea-3m-Hematologic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

GLIPR1 CLEC4E CCR5 ARHGAP45

5.10e-051715348e14288cd14593c939636c656980535e26d0d98e
ToppCelldroplet-Marrow-nan-21m-Hematologic-proerythroblast|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E HCAR2 SAMHD1

5.10e-05171534d6ae456e88ec49a8609a5e5e3af9f51921e66744
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HCAR3 CLEC4E HCAR2 ADGRG3

5.10e-05171534ef9397cec7f5c217d34583f26270af7ed7fbcebf
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NPC1 GLIPR1 CCDC88A SAMHD1

5.10e-05171534af1c93eb75f45c042ea475d93db56e4da207e31f
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Lymphocytic-T_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E RFC5 ARHGAP45

5.10e-05171534c60313b045cb77c0923ddb81bbd1a654aa1087c5
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E CCR5 ARHGAP45

5.22e-05172534dd2ab9a5652dc152841d73e25a9e7c40a8faa2a5
ToppCellsevere_COVID-19-Neutrophil|severe_COVID-19 / disease group, cell group and cell class (v2)

HCAR3 CLEC4E HCAR2 ADGRG3

5.22e-051725348f4bcb9b2bbf8b4333f673d8ad6bb88dfda4792a
ToppCelldroplet-Pancreas-PANCREAS-30m-Hematologic|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E CCR5 ARHGAP45

5.22e-0517253417938d191e28f88cccf180dc1aaf453a255fc031
ToppCelldroplet-Pancreas-PANCREAS-30m-Hematologic-leukocyte|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E CCR5 ARHGAP45

5.22e-05172534480f409405d1d35804629e81fc6ec5873a085983
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E CCR5 ARHGAP45

5.22e-05172534ce0c63fa83d68621445ba3e4d23c8a5e1a4db95e
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HCAR3 CLEC4E HCAR2 ADGRG3

5.34e-051735341edef5aeab626cbf2c09468e77b02cfa2d21ba03
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HCAR3 CLEC4E HCAR2 ADGRG3

5.34e-05173534c37dba3804df7c3151e18e6ae4e0b6e7a92bae97
ToppCellBAL-Severe-Myeloid-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HCAR3 CLEC4E HCAR2 ADGRG3

5.34e-051735345b76d9cc56bbb29017e64a2d0a3c76c0be003d96
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil-Neu_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HCAR3 CLEC4E HCAR2 ADGRG3

5.34e-05173534bf685025961e79b379f2c35464b6c8ce3e31ace0
ToppCellBAL-Severe-Myeloid-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HCAR3 CLEC4E HCAR2 ADGRG3

5.34e-05173534a6e73a40b0d5356564a594053e772f9d061a5919
ToppCellMacrophages-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

HCAR3 HCAR2 CCDC88A SAMHD1

5.34e-05173534a112da5b0ab6e1f13d1a7dfa72c67c9a95fa9243
ToppCellBAL-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HCAR3 CLEC4E HCAR2 ADGRG3

5.34e-05173534a8b5370f4c893a20c58e97659f3ac168699693f8
ToppCellsevere_influenza-Neutrophil|World / disease group, cell group and cell class (v2)

HCAR3 CLEC4E HCAR2 ADGRG3

5.46e-05174534f9f07436b7d3f190800cd85d229f007032f391e1
ToppCelldroplet-Pancreas-PANCREAS-30m-Hematologic-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLIPR1 CLEC4E CCR5 ARHGAP45

5.58e-05175534ca2eabf03b70353e7eb15b6f622b2f9223a99e18
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RIC8B PHF20 ASTE1 PHF13

5.71e-0517653424b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

GLIPR1 CCDC88A SAMHD1 IDH3A

5.71e-051765348488997e0f02e874f53fae1690da63e0dd1d0780
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRCH2 SCN2A ASTE1 MED12L

5.83e-051775348abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCellSevere_COVID-19-Myeloid-Neutrophil|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

HCAR3 CLEC4E HCAR2 ADGRG3

5.83e-05177534a6fae376f1beb1df423484d9b1bd1d954ca117af
ToppCellSevere-Myeloid-Neutrophil|Severe / Condition, Lineage, Cell class and cell subclass

HCAR3 CLEC4E HCAR2 ADGRG3

5.96e-05178534454313efe59d71e7327b9758efabf2d893e4a8fd
ToppCellSevere-Myeloid-Neutrophil-|Severe / Condition, Lineage, Cell class and cell subclass

HCAR3 CLEC4E HCAR2 ADGRG3

5.96e-051785348618ae891d62bf70fe860ff7bb2d31868961aa13
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIPR1 HCAR3 HCAR2 SAMHD1

5.96e-051785348184a2b9872f7ca12a9823535de485e841aeffb1
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIPR1 HCAR3 HCAR2 SAMHD1

6.09e-05179534409364d916c5e7e2291284cc74351d8f8a8447ac
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-CD141+_DCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

GLIPR1 CCDC88A SAMHD1 IDH3A

6.09e-0517953499894067e2c2a3ed53abdc5434410c3172693496
ToppCell10x5'-GI_large-bowel-Myeloid_Dendritic|GI_large-bowel / Manually curated celltypes from each tissue

HCAR3 CLEC4E HCAR2 SAMHD1

6.23e-05180534400f48aa2851d89bf3b60d721bc0f635f3ad86eb
ToppCell10x5'-GI_large-bowel-Myeloid_Dendritic-DC2|GI_large-bowel / Manually curated celltypes from each tissue

HCAR3 CLEC4E HCAR2 SAMHD1

6.23e-05180534d4ebe67a2735e244c08b238320bbb441ca88ee6f
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GLIPR1 HCAR3 HCAR2 SAMHD1

6.36e-05181534bad77767e64cc093a827a6b0f3f401f3f108e457
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HCAR3 CLEC4E HCAR2 ADGRG3

6.36e-051815343457c1d431db4282be5a6243119e48960748ede7
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Monocytes|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HCAR3 CLEC4E HCAR2 SAMHD1

6.36e-051815347b6454972041a9b4e4ff2f313e8432d9040b8544
ToppCellTCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2|TCGA-Skin / Sample_Type by Project: Shred V9

NPC1 RCHY1 PPIP5K1 MIGA1

6.36e-051815349d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCellwk_20-22-Hematologic-Myeloid-pDC|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NPC1 CCDC88A SAMHD1 IDH3A

6.36e-0518153460607c5ff6d5b1cb416adc034491dca31c41e988
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-pDC|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NPC1 GLIPR1 CCDC88A IDH3A

6.50e-0518253402c0824373a0ecebc922d4ca848ace9d570722c4
ToppCellwk_20-22-Hematologic-Myeloid-Basophil|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

HCAR3 HCAR2 FRY ADGRG3

6.64e-0518353493d821d5340caed0eef455d3d738be213ce5fff8
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Macrophages|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HCAR3 CLEC4E HCAR2 SAMHD1

6.64e-0518353492d5a61b57851090eba558f19e2a7010043eff81
ToppCell10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HCAR3 HCAR2 ADGRG3 ZBTB11

6.64e-05183534f9a3af96c0fb7d5c4d7df6db8b2c42e322418c08
ToppCellNS-moderate-d_07-13-Myeloid-Neutrophil|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

HCAR3 CLEC4E HCAR2 ADGRG3

6.78e-051845344c7d05f1a4556b13cedbaaf88d67ac32d09b109b
ToppCellwk_08-11-Hematologic-Myeloid-DC3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

GLIPR1 CLEC4E SAMHD1 ARHGAP45

6.78e-051845347d9294e5a55964903feda135e5bea0338824ed83
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Myeloid-Monocytes|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HCAR3 CLEC4E HCAR2 SAMHD1

6.92e-0518553400a991e63e9ac6de3f48a96e3be6073f90cbb442
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-cDC2|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HCAR3 HCAR2 CCDC88A SAMHD1

7.07e-0518653444785bd171f424ad61437275026439fae3cb8d8c
ToppCellPCW_07-8.5-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

GLIPR1 CLEC4E CCR5 ARHGAP45

7.22e-0518753423be50d81f4404a609dea821e1a66d221c0e0615
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HCAR3 CLEC4E HCAR2 ADGRG3

7.22e-0518753475bc05a0ba2727fecc236903ace792a28f3d3c9a
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_0|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HCAR3 CLEC4E HCAR2 ADGRG3

7.22e-05187534a0d59bf1043ff5a1e8110b39ecc2d3932675edd4
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_granulocytic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HCAR3 CLEC4E HCAR2 ADGRG3

7.37e-0518853436ff615154d6d9e3ba6ccb73a0f11574bcbf5ece
ToppCell10x5'v1-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

HCAR3 HCAR2 FRY ADGRG3

7.37e-05188534b4d695c373195d389e0a579e9589e87433286b24
ToppCell10x3'2.3-week_14-16-Myeloid_DC-DC-DC2|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

GLIPR1 CCDC88A CCR5 SAMHD1

7.37e-0518853415d8dc514d5da46f6af284e7c1c92c606712dae6
ToppCellwk_08-11-Hematologic-Myeloid-Promonocyte-like|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

HCAR3 ADGRG3 SAMHD1 ARHGAP45

7.37e-051885342ae945d96a011f246d04a42bcd6ef443232b03f4
ToppCellCOVID-19_Severe-Myeloid_G-Neutrophil|COVID-19_Severe / Disease group, lineage and cell class

HCAR3 CLEC4E HCAR2 ADGRG3

7.52e-05189534a62f4c445ede00d15b74bee65f4e4fb54cfd4d32
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HCAR3 CLEC4E HCAR2 ADGRG3

7.52e-05189534f6b2b4824505f0119a017fdb73c55418fb651645
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

HCAR3 CLEC4E HCAR2 ADGRG3

7.52e-05189534db8e314ce95c32542bb4015a77032a33211fea0b
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HCAR3 CLEC4E HCAR2 ADGRG3

7.52e-05189534235c24eeab5139f5821fccd5c879d8787682f4ef
ToppCellPBMC-Severe-Myeloid-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HCAR3 CLEC4E HCAR2 ADGRG3

7.68e-05190534cb62ece5929896dfba30a4f563c6ba5a5712b71e
ToppCellPBMC-Severe-Myeloid-Neutrophil|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

HCAR3 CLEC4E HCAR2 ADGRG3

7.68e-05190534fedd266198d294d8da8c9e217e5e0cb8b2e1b566
ToppCell10x3'2.3-week_17-19-Myeloid_DC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GLIPR1 CCR5 SAMHD1 IDH3A

7.68e-051905341687e133a88c3d036a33a4f8aeefe320a4f02c39
ToppCell10x3'2.3-week_17-19-Myeloid_DC-DC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

GLIPR1 CCR5 SAMHD1 IDH3A

7.68e-051905343cfc2646ba25b4bd8bb443cc1f46e18a270a1969
ToppCellCOVID-19_Severe-Myeloid_G|COVID-19_Severe / Disease group, lineage and cell class

HCAR3 CLEC4E HCAR2 ADGRG3

7.68e-051905348a81cb90273c361e9fdfaa0a31806da253fa1388
ToppCellCOVID-19-kidney-Myeloid|kidney / Disease (COVID-19 only), tissue and cell type

ANKRD44 HCAR3 CLEC4E ADGRG3

7.99e-05192534441cd1ec171f643b28e1f6f9c04def629cc7391b
Diseasemetabolic syndrome

NPC1 HCAR3 HCAR2 HECTD4

3.99e-04200514EFO_0000195
DiseaseIntellectual Disability

FRY PPP2R5D KDM5A MED12L ZBTB11

1.03e-03447515C3714756
Diseasehepatitis C (is_implicated_in)

CCR5 SAMHD1

1.08e-0328512DOID:1883 (is_implicated_in)
DiseaseSquamous cell carcinoma

HCAR3 HCAR2 PRKDC

1.30e-03124513C0007137
Diseaseeyelid sagging measurement

ANKRD44 TTC27

1.41e-0332512EFO_0009360

Protein segments in the cluster

PeptideGeneStartEntry
ELFLKKLQQCCVIFD

PPP2R5E

61

Q16537
ELFIQKLRQCCVLFD

PPP2R5D

116

Q14738
IFNLNDKALCFTKCR

ADGRG3

41

Q86Y34
IAKRFCKCCSIFQQE

CCR5

316

P51681
IKLCEGFNEVLKQCR

CHCHD2

131

Q9Y6H1
VLIKLRVCFVQCFSE

ASTE1

126

Q2TB18
CIVRFIVSKNKCEFV

KCNG3

236

Q8TAE7
QFLKKAVDVLCQCRA

ARIH1

456

Q9Y4X5
KLDECFQIFRDFCTK

FHDC1

441

Q9C0D6
IQDYDFKTRICKKVC

GLIPR1

121

P48060
FIVKKCVCEIERRAL

ARHGAP45

776

Q92619
CEKVEFVNLVLLFCE

MED12L

591

Q86YW9
LEIDKKNCCVFRDDF

HCAR2

11

Q8TDS4
KNCCVFRDDFIVKVL

HCAR2

16

Q8TDS4
NKCALCAEIFKQRFS

SPINK5

256

Q9NQ38
FEKRAKIFCARQNCS

DDX58

856

O95786
CAVQCQKKEEFIERI

CCDC88A

131

Q3V6T2
FIEFVCKHDEVLKCF

HACE1

476

Q8IYU2
DFCKVLVVEFINEIC

HERC6

696

Q8IVU3
NCIEVLLEQKCFRKF

ANKRD44

786

Q8N8A2
EELCKFIKFACNQER

HECTD4

3906

Q9Y4D8
FRNLKEKCFVTQLAC

NBPF1

306

Q3BBV0
DRIEEVKFCICRKTA

KDM5A

1156

P29375
DIKRQEKNRLDIFCC

NPC1

786

O15118
FLQKCREVAESCKDI

IDH3A

211

P50213
RAVCQIKIFCDKGAE

GRHL3

391

Q8TE85
AEVCEKIGCLQRFKE

CEP290

926

O15078
ECLKKQLEFCFSREN

LARP4

121

Q71RC2
QFCKDIAERIAQVCL

FRY

2161

Q5TBA9
FKNIQKRFCFLTCDA

FRY

2711

Q5TBA9
AVREKVFDVIIRCFK

HARS1

71

P12081
KCVSLKRNDFQEACV

KBTBD6

506

Q86V97
AKCRRNVENFLDACK

LRCH2

706

Q5VUJ6
CKDCKVIRCQFSTFE

MTMR3

91

Q13615
VDLDHKFRCKVVDCL

PHF20

446

Q9BVI0
CCFFKNQVLLFLKDI

MIGA1

556

Q8NAN2
KFARVCEVDNELRIC

SAMHD1

336

Q9Y3Z3
VIEKFTENTRFCLIC

RFC5

141

P40937
CKDRKFINDIKCFDL

RIC8B

151

Q9NVN3
KQIAAEFLFVLCKER

RIC8B

421

Q9NVN3
LEIDKKNCCVFRDDF

HCAR3

11

P49019
KNCCVFRDDFIAKVL

HCAR3

16

P49019
DRIFVCDKHKILFCQ

CHST10

111

O43529
RCVVTFRIFQTCDEK

CLEC4E

41

Q9ULY5
VFVCQKCRDSKFDIR

PHF13

271

Q86YI8
FKDNCCKREILALQI

TRAF3

101

Q13114
LERVCEKCGRKFTQL

ZBTB11

856

O95625
ICDIAREKVNKAAVF

NAA35

156

Q5VZE5
FTEDCVRKFKCCQIS

SCN2A

1171

Q99250
CREEILKFLCIFLEK

PRKDC

81

P78527
ECKECGKAFRVRQQL

ZFP82

171

Q8N141
QLDRFKVKEVQCINC

RCHY1

51

Q96PM5
KEFQECVECFERSVK

TTC27

541

Q6P3X3
RKVCVAFKQTVCGFD

PPIP5K1

306

Q6PFW1
ECNICKVRFTRQDKL

ZBTB7A

411

O95365
CNECGKAFIERSKLV

ZNF836

836

Q6ZNA1
ICKECGKVFIQRSEL

ZNF175

336

Q9Y473
EFLVQFRQDKVCVKF

MYO1B

1096

O43795