Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunction20-hydroxy-leukotriene B4 omega oxidase activity

CYP4F2 CYP4F3

2.43e-052992GO:0097258
GeneOntologyMolecularFunction20-aldehyde-leukotriene B4 20-monooxygenase activity

CYP4F2 CYP4F3

2.43e-052992GO:0097259
GeneOntologyMolecularFunctionamino-acid betaine transmembrane transporter activity

SLC22A4 SLC22A5

1.45e-044992GO:0015199
GeneOntologyMolecularFunctionalpha-tocopherol omega-hydroxylase activity

CYP4F2 CYP4F3

2.41e-045992GO:0052871
GeneOntologyMolecularFunctioncarnitine transmembrane transporter activity

SLC22A4 SLC22A5

3.60e-046992GO:0015226
GeneOntologyMolecularFunctionleukotriene-B4 20-monooxygenase activity

CYP4F2 CYP4F3

5.03e-047992GO:0050051
GeneOntologyMolecularFunctionuridylyltransferase activity

TUT4 UAP1L1

5.03e-047992GO:0070569
GeneOntologyMolecularFunctionalkane 1-monooxygenase activity

CYP4F2 CYP4F3

5.03e-047992GO:0018685
GeneOntologyMolecularFunctionarachidonate omega-hydroxylase activity

CYP4F2 CYP4F3

1.07e-0310992GO:0052869
GeneOntologyMolecularFunctionhistone H3K4 trimethyltransferase activity

PRDM9 KMT2D

1.07e-0310992GO:0140999
GeneOntologyMolecularFunctionfatty acid omega-hydroxylase activity

CYP4F2 CYP4F3

1.07e-0310992GO:0120250
GeneOntologyMolecularFunctionlong-chain fatty acid omega-hydroxylase activity

CYP4F2 CYP4F3

1.07e-0310992GO:0102033
GeneOntologyMolecularFunctionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen

CYP4F2 CYP4F3

1.83e-0313992GO:0016713
DomainHTH_Psq

CENPB LCORL TIGD6

2.89e-0512973IPR007889
DomainHTH_PSQ

CENPB LCORL TIGD6

2.89e-0512973PS50960
Domainzf-B_box

TRIM58 TRIM23 TRIM9 TRIM17 RNF207

3.62e-0572975PF00643
DomainZF_BBOX

TRIM58 TRIM23 TRIM9 TRIM17 RNF207

6.02e-0580975PS50119
DomainZnf_B-box

TRIM58 TRIM23 TRIM9 TRIM17 RNF207

6.39e-0581975IPR000315
DomainDUF3446

EGR2 EGR3

7.98e-053972IPR021849
DomainDUF3446

EGR2 EGR3

7.98e-053972PF11928
DomainZF_RING_1

TRIM58 TRIM23 KMT2D TRIM9 TRIM17 RNF216 RNF207 PDZRN4

1.37e-04291978PS00518
DomainZF_RING_2

TRIM58 TRIM23 KMT2D TRIM9 TRIM17 RNF216 RNF207 PDZRN4

1.62e-04298978PS50089
DomainZnf_RING_CS

TRIM58 TRIM23 TRIM9 TRIM17 RNF207 PDZRN4

2.07e-04163976IPR017907
DomainBBOX

TRIM58 TRIM23 TRIM9 TRIM17

4.56e-0469974SM00336
DomainOrgcat_transp/SVOP

SLC22A4 SLC22A5

9.39e-049972IPR004749
DomainRING

TRIM58 TRIM23 KMT2D TRIM9 TRIM17 RNF207 PDZRN4

1.06e-03305977SM00184
DomainSPRY

TRIM58 BTN2A1 TRIM9 TRIM17

1.09e-0387974SM00449
DomainCENP-B_N

CENPB TIGD6

1.17e-0310972PF04218
DomainSPRY

TRIM58 BTN2A1 TRIM9 TRIM17

1.46e-0394974PF00622
DomainSPRY_dom

TRIM58 BTN2A1 TRIM9 TRIM17

1.46e-0394974IPR003877
DomainB30.2/SPRY

TRIM58 BTN2A1 TRIM9 TRIM17

1.52e-0395974IPR001870
DomainB302_SPRY

TRIM58 BTN2A1 TRIM9 TRIM17

1.52e-0395974PS50188
DomainZnf_RING

TRIM58 TRIM23 KMT2D TRIM9 TRIM17 RNF207 PDZRN4

1.55e-03326977IPR001841
DomainCENPB

CENPB TIGD6

1.70e-0312972SM00674
DomainDDE_1

CENPB TIGD6

1.70e-0312972PF03184
DomainDDE_SF_endonuclease_dom

CENPB TIGD6

1.70e-0312972IPR004875
DomainPRY

TRIM58 BTN2A1 TRIM17

1.98e-0348973SM00589
DomainPRY

TRIM58 BTN2A1 TRIM17

1.98e-0348973IPR006574
DomainHTH_CENPB

CENPB TIGD6

2.01e-0313972PS51253
DomainHTH_Tnp_Tc5

CENPB TIGD6

2.01e-0313972PF03221
DomainHTH_CenpB_DNA-bd_dom

CENPB TIGD6

2.01e-0313972IPR006600
DomainZINC_FINGER_C2H2_1

TUT4 ZNF786 PRDM9 ZSCAN10 ZNF394 EGR2 EGR3 ZNF764 ZNF335 ZNF398 ZNF579

2.31e-037779711PS00028
DomainQuinoprotein_ADH-like_supfam

GEMIN5 WDR27 EML5

2.64e-0353973IPR011047
DomainBbox_C

TRIM23 TRIM9

2.68e-0315972IPR003649
DomainBBC

TRIM23 TRIM9

2.68e-0315972SM00502
Domain-

ZNF786 PRDM9 ZSCAN10 ZNF394 EGR2 EGR3 ZNF764 ZNF335 ZNF398 ZNF579

2.76e-0367997103.30.160.60
DomainZnf_C2H2-like

ZNF318 ZNF786 PRDM9 ZSCAN10 ZNF394 EGR2 EGR3 ZNF764 ZNF335 ZNF398 ZNF579

2.78e-037969711IPR015880
DomainZnf_C2H2

ZNF786 TRIM23 PRDM9 ZSCAN10 ZNF394 EGR2 EGR3 ZNF764 ZNF335 ZNF398 ZNF579

3.03e-038059711IPR007087
DomainZnF_C2H2

ZNF318 ZNF786 PRDM9 ZSCAN10 ZNF394 EGR2 EGR3 ZNF764 ZNF335 ZNF398 ZNF579

3.12e-038089711SM00355
Domainzf-C2H2

ZNF786 PRDM9 ZSCAN10 ZNF394 EGR2 EGR3 ZNF764 ZNF335 ZNF398 ZNF579

3.19e-036939710PF00096
DomainZnf_C2H2/integrase_DNA-bd

ZNF786 PRDM9 ZSCAN10 ZNF394 EGR2 EGR3 ZNF764 ZNF335 ZNF398 ZNF579

3.23e-036949710IPR013087
DomainApc4_WD40_dom

GEMIN5 EML5

4.77e-0320972IPR024977
DomainANAPC4_WD40

GEMIN5 EML5

4.77e-0320972PF12894
DomainAnk_2

SHANK1 GLS2 ANKRD10 ASAP3 ASB18

5.28e-03215975PF12796
DomainButyrophylin

TRIM58 BTN2A1 TRIM17

5.78e-0370973IPR003879
Domain-

TRIM58 TRIM9 TRIM17

6.01e-03719734.10.45.10
Domain-

RIPOR3 ATAD2 DNAAF5 ARVCF ARMC5

6.03e-032229751.25.10.10
Domainzf-C3HC4

TRIM58 TRIM23 TRIM9 TRIM17 RNF207

6.15e-03223975PF00097
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TBC1D9B ITPRIPL2 LPAR5 KIF26A MTG2 GEMIN5 KDM6B STK11IP BAHD1 ARHGEF10L JAK3 KMT2D ARVCF ZNF335 ZNF398 ZNF579

1.23e-0711051011635748872
Pubmed

Deletion of TECRL promotes skeletal muscle repair by up-regulating EGR2.

TECRL EGR2

8.35e-062101238753506
Pubmed

Haplotype in the IBD5 region is associated with refractory Crohn's disease in Slovenian patients and modulates expression of the SLC22A5 gene.

SLC22A4 SLC22A5

8.35e-062101221695374
Pubmed

Molecular and functional characterization of organic cation/carnitine transporter family in mice.

SLC22A4 SLC22A5

8.35e-062101211010964
Pubmed

Analysis of the influence of OCTN1/2 variants within the IBD5 locus on disease susceptibility and growth indices in early onset inflammatory bowel disease.

SLC22A4 SLC22A5

8.35e-062101216469794
Pubmed

Gene expression of carnitine organic cation transporters 1 and 2 (OCTN) is downregulated in patients with ulcerative colitis.

SLC22A4 SLC22A5

8.35e-062101221910182
Pubmed

Association of SLC22A4/5 polymorphisms with steroid responsiveness of inflammatory bowel disease in Japan.

SLC22A4 SLC22A5

8.35e-062101218274826
Pubmed

Cloning and expression of a novel form of leukotriene B4 omega-hydroxylase from human liver.

CYP4F2 CYP4F3

8.35e-06210128026587
Pubmed

Expression patterns of the organic cation/carnitine transporter family in adult murine brain.

SLC22A4 SLC22A5

8.35e-062101217576045
Pubmed

Substrate discrimination by ergothioneine transporter SLC22A4 and carnitine transporter SLC22A5: gain-of-function by interchange of selected amino acids.

SLC22A4 SLC22A5

8.35e-062101219814996
Pubmed

Functional genetic variation in the basal promoter of the organic cation/carnitine transporters OCTN1 (SLC22A4) and OCTN2 (SLC22A5).

SLC22A4 SLC22A5

8.35e-062101219141711
Pubmed

EGR3 as a potential susceptibility gene for schizophrenia in Korea.

EGR2 EGR3

8.35e-062101220687139
Pubmed

Egr-2 and Egr-3 are negative regulators of T cell activation.

EGR2 EGR3

8.35e-062101215834410
Pubmed

Transcription factors early growth response gene (Egr) 2 and 3 control inflammatory responses of tolerant T cells.

EGR2 EGR3

8.35e-062101229314730
Pubmed

Contribution of the IBD5 locus to Crohn's disease in the Swedish population.

SLC22A4 SLC22A5

8.35e-062101217340776
Pubmed

Prevalence of SLC22A4 1672T and SLC22A5 -207C combination defined TC haplotype in Hungarian ulcerative colitis patients.

SLC22A4 SLC22A5

8.35e-062101217387389
Pubmed

NFκB and MAPK signalling pathways mediate TNFα-induced Early Growth Response gene transcription leading to aromatase expression.

EGR2 EGR3

8.35e-062101223485457
Pubmed

Tooth loss and adiposity: possible role of carnitine transporter (OCTN1/2) polymorphisms in women but not in men.

SLC22A4 SLC22A5

8.35e-062101232964310
Pubmed

Oxaliplatin transport mediated by organic cation/carnitine transporters OCTN1 and OCTN2 in overexpressing human embryonic kidney 293 cells and rat dorsal root ganglion neurons.

SLC22A4 SLC22A5

8.35e-062101221606177
Pubmed

Direct or indirect association in a complex disease: the role of SLC22A4 and SLC22A5 functional variants in Crohn disease.

SLC22A4 SLC22A5

8.35e-062101216835882
Pubmed

Transport of ipratropium, an anti-chronic obstructive pulmonary disease drug, is mediated by organic cation/carnitine transporters in human bronchial epithelial cells: implications for carrier-mediated pulmonary absorption.

SLC22A4 SLC22A5

8.35e-062101220020740
Pubmed

[Possible role of selected IGR and SLC22A4/SLC22A5 loci in development of inflammatory bowel diseases].

SLC22A4 SLC22A5

8.35e-062101219581171
Pubmed

Polymorphisms in the organic cation transporter genes SLC22A4 and SLC22A5 and Crohn's disease in a New Zealand Caucasian cohort.

SLC22A4 SLC22A5

8.35e-062101216519742
Pubmed

Functional activity of L-carnitine transporters in human airway epithelial cells.

SLC22A4 SLC22A5

8.35e-062101226607009
Pubmed

OCTNs: will the real IBD5 gene please stand up?

SLC22A4 SLC22A5

8.35e-062101216773684
Pubmed

Association of the organic cation transporter OCTN genes with Crohn's disease in the Spanish population.

SLC22A4 SLC22A5

8.35e-062101216333318
Pubmed

Association of the OCTN1/1672T variant with increased risk for colorectal cancer in young individuals and ulcerative colitis patients.

SLC22A4 SLC22A5

8.35e-062101221793125
Pubmed

Organic cation/carnitine transporter family expression patterns in adult murine heart.

SLC22A4 SLC22A5

8.35e-062101219233567
Pubmed

The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells.

EGR2 EGR3

8.35e-062101223021953
Pubmed

Expression and localization of carnitine/organic cation transporter OCTN1 and OCTN2 in ocular epithelium.

SLC22A4 SLC22A5

8.35e-062101218641280
Pubmed

SLC22A4 and SLC22A5 gene polymorphisms and Crohn's disease in the Chinese Han population.

SLC22A4 SLC22A5

8.35e-062101219659785
Pubmed

Characterization of organic cation/carnitine transporter family in human sperm.

SLC22A4 SLC22A5

8.35e-062101212788076
Pubmed

Egr2 and 3 control adaptive immune responses by temporally uncoupling expansion from T cell differentiation.

EGR2 EGR3

8.35e-062101228487311
Pubmed

Association between OCTN1/2 gene polymorphisms (1672C-T, 207G-C) and susceptibility of Crohn's disease: a meta-analysis.

SLC22A4 SLC22A5

8.35e-062101221706137
Pubmed

Evidence for association of OCTN genes and IBD5 with ulcerative colitis.

SLC22A4 SLC22A5

8.35e-062101216361305
Pubmed

Emerging roles of Egr2 and Egr3 in the control of systemic autoimmunity.

EGR2 EGR3

8.35e-062101227856665
Pubmed

Evidence for the association of the SLC22A4 and SLC22A5 genes with type 1 diabetes: a case control study.

SLC22A4 SLC22A5

8.35e-062101216796743
Pubmed

Egr2 and 3 control inflammation, but maintain homeostasis, of PD-1high memory phenotype CD4 T cells.

EGR2 EGR3

8.35e-062101232709717
Pubmed

Expression and functional analysis of intestinal organic cation/L-carnitine transporter (OCTN) in Crohn's disease.

SLC22A4 SLC22A5

8.35e-062101222325173
Pubmed

Polymorphisms in OCTN1 and OCTN2 transporters genes are associated with prolonged time to progression in unresectable gastrointestinal stromal tumours treated with imatinib therapy.

SLC22A4 SLC22A5

8.35e-062101223127916
Pubmed

Egr2 and 3 maintain anti-tumour responses of exhausted tumour infiltrating CD8 + T cells.

EGR2 EGR3

8.35e-062101236342511
Pubmed

LPS-induced inflammation delays the transportation of ASP+ due to down-regulation of OCTN1/2 in alveolar epithelial cells.

SLC22A4 SLC22A5

8.35e-062101231591905
Pubmed

Early growth response transcriptional regulators are dispensable for macrophage differentiation.

EGR2 EGR3

2.50e-053101217312150
Pubmed

A risk haplotype in the Solute Carrier Family 22A4/22A5 gene cluster influences phenotypic expression of Crohn's disease.

SLC22A4 SLC22A5

2.50e-053101215685536
Pubmed

Hepatitis B virus X protein induces expression of Fas ligand gene through enhancing transcriptional activity of early growth response factor.

EGR2 EGR3

2.50e-053101215173177
Pubmed

Human CYP4F3s are the main catalysts in the oxidation of fatty acid epoxides.

CYP4F2 CYP4F3

2.50e-053101215145985
Pubmed

Functional variants of OCTN cation transporter genes are associated with Crohn disease.

SLC22A4 SLC22A5

2.50e-053101215107849
Pubmed

Contribution of OCTN variants within the IBD5 locus to pediatric onset Crohn's disease.

SLC22A4 SLC22A5

2.50e-053101216771961
Pubmed

Polymorphisms in the IBD5 locus are associated with Crohn disease in pediatric Ashkenazi Jewish patients.

SLC22A4 SLC22A5

2.50e-053101219412005
Pubmed

Evidence for common genetic control in pathways of inflammation for Crohn's disease and psoriatic arthritis.

SLC22A4 SLC22A5

2.50e-053101216255050
Pubmed

Early growth response genes 2 and 3 induced by AP-1 and NF-κB modulate TGF-β1 transcription in NK1.1- CD4+ NKG2D+ T cells.

EGR2 EGR3

2.50e-053101233011290
Pubmed

Expression of the organic cation/carnitine transporter family (Octn1,-2 and-3) in mdx muscle and heart: Implications for early carnitine therapy in Duchenne muscular dystrophy to improve cellular carnitine homeostasis.

SLC22A4 SLC22A5

2.50e-053101232070725
Pubmed

Uncontrolled CD21low age-associated and B1 B cell accumulation caused by failure of an EGR2/3 tolerance checkpoint.

EGR2 EGR3

2.50e-053101235045301
Pubmed

Variants of OCTN1-2 cation transporter genes are associated with both Crohn's disease and ulcerative colitis.

SLC22A4 SLC22A5

2.50e-053101216441470
Pubmed

IGR2096a_1 T and IGR2198a_1 C alleles on IBD5 locus of chromosome 5q31 region confer risk for Crohn's disease in Hungarian patients.

SLC22A4 SLC22A5

2.50e-053101219214536
Pubmed

The contribution of OCTN1/2 variants within the IBD5 locus to disease susceptibility and severity in Crohn's disease.

SLC22A4 SLC22A5

2.50e-053101216344054
Pubmed

OCTN and CARD15 gene polymorphism in Chinese patients with inflammatory bowel disease.

SLC22A4 SLC22A5

2.50e-053101218756601
Pubmed

Role of SLC22A4, SLC22A5, and RUNX1 genes in rheumatoid arthritis.

SLC22A4 SLC22A5

2.50e-053101216652416
Pubmed

Egr2 and 3 Inhibit T-bet-Mediated IFN-γ Production in T Cells.

EGR2 EGR3

2.50e-053101228455436
Pubmed

Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-β3 production.

EGR2 EGR3

2.50e-053101227911796
Pubmed

Early Growth Response Genes 2 and 3 Regulate the Expression of Bcl6 and Differentiation of T Follicular Helper Cells.

EGR2 EGR3

2.50e-053101225979336
Pubmed

Polymorphisms in the DLG5 and OCTN cation transporter genes in Crohn's disease.

SLC22A4 SLC22A5

2.50e-053101215955786
Pubmed

Lack of association between IBD5 and Crohn's disease in Japanese patients demonstrates population-specific differences in inflammatory bowel disease.

SLC22A4 SLC22A5

2.50e-053101216373276
Pubmed

Deorphaning a solute carrier 22 family member, SLC22A15, through functional genomic studies.

SLC22A4 SLC22A5

2.50e-053101233124720
Pubmed

Prevalence of SLC22A4, SLC22A5 and CARD15 gene mutations in Hungarian pediatric patients with Crohn's disease.

SLC22A4 SLC22A5

2.50e-053101217006998
Pubmed

Epidermal-growth-factor-induced proliferation of astrocytes requires Egr transcription factors.

EGR2 EGR3

2.50e-053101219706684
Pubmed

Role of CARD15, DLG5 and OCTN genes polymorphisms in children with inflammatory bowel diseases.

SLC22A4 SLC22A5

4.99e-054101217451203
Pubmed

Risk factors for perianal Crohn's disease: the role of genotype, phenotype, and ethnicity.

SLC22A4 SLC22A5

4.99e-054101217509030
Pubmed

An amphioxus Krox gene: insights into vertebrate hindbrain evolution.

EGR2 EGR3

4.99e-054101211180801
Pubmed

rs1004819 is the main disease-associated IL23R variant in German Crohn's disease patients: combined analysis of IL23R, CARD15, and OCTN1/2 variants.

SLC22A4 SLC22A5

4.99e-054101217786191
Pubmed

Runt-related transcription factor 3 is associated with ulcerative colitis and shows epistasis with solute carrier family 22, members 4 and 5.

SLC22A4 SLC22A5

4.99e-054101218668679
Pubmed

Single nucleotide polymorphisms of OCTN1, OCTN2, and DLG5 genes in Greek patients with Crohn's disease.

SLC22A4 SLC22A5

4.99e-054101216437728
Pubmed

Mstn knockdown decreases the trans-differentiation from myocytes to adipocytes by reducing Jmjd3 expression via the SMAD2/SMAD3 complex.

KDM6B MSTN

4.99e-054101231334687
Pubmed

EGR1, EGR2, and EGR3 activate the expression of their coregulator NAB2 establishing a negative feedback loop in cells of neuroectodermal and epithelial origin.

EGR2 EGR3

4.99e-054101220506119
Pubmed

Transport of gabapentin by LAT1 (SLC7A5).

SLC22A4 SLC22A5

4.99e-054101223567998
Pubmed

A third human carnitine/organic cation transporter (OCTN3) as a candidate for the 5q31 Crohn's disease locus (IBD5).

SLC22A4 SLC22A5

4.99e-054101212535646
Pubmed

Immediate early genes krox-24 and krox-20 are rapidly up-regulated after wounding in the embryonic and adult mouse.

EGR2 EGR3

4.99e-054101211891986
Pubmed

Association of organic cation transporter risk haplotype with perianal penetrating Crohn's disease but not with susceptibility to IBD.

SLC22A4 SLC22A5

4.99e-054101216344053
Pubmed

Omega oxidation of 3-hydroxy fatty acids by the human CYP4F gene subfamily enzyme CYP4F11.

CYP4F2 CYP4F3

4.99e-054101218065749
Pubmed

Relationship between CARD15, SLC22A4/5, and DLG5 polymorphisms and early-onset inflammatory bowel diseases: an Italian multicentric study.

SLC22A4 SLC22A5

4.99e-054101216670523
Pubmed

Understanding the Role of the SMN Complex Component GEMIN5 and Its Functional Relationship with Demethylase KDM6B in the Flunarizine-Mediated Neuroprotection of Motor Neuron Disease Spinal Muscular Atrophy.

GEMIN5 KDM6B

4.99e-054101239337533
Pubmed

Integrated analysis of DNA methylation and RNA‑sequencing data in Down syndrome.

EGR2 EGR3

8.30e-055101227667480
Pubmed

Egr2-independent, Klf1-mediated induction of PD-L1 in CD4+ T cells.

EGR2 EGR3

8.30e-055101229728568
Pubmed

Genetic susceptibility has a more important role in pediatric-onset Crohn's disease than in adult-onset Crohn's disease.

SLC22A4 SLC22A5

8.30e-055101217476680
Pubmed

The ATG16L1 gene variants rs2241879 and rs2241880 (T300A) are strongly associated with susceptibility to Crohn's disease in the German population.

SLC22A4 SLC22A5

8.30e-055101218162085
Pubmed

Opposing regulation of T cell function by Egr-1/NAB2 and Egr-2/Egr-3.

EGR2 EGR3

8.30e-055101218203138
Pubmed

HIV Tat binds Egr proteins and enhances Egr-dependent transactivation of the Fas ligand promoter.

EGR2 EGR3

8.30e-055101211909874
Pubmed

Id3 Restricts γδ NKT Cell Expansion by Controlling Egr2 and c-Myc Activity.

EGR2 EGR3

8.30e-055101230012846
Pubmed

The gene encoding early growth response 2, a target of the transcription factor NFAT, is required for the development and maturation of natural killer T cells.

EGR2 EGR3

8.30e-055101219169262
Pubmed

Cytochromes P450 from family 4 are the main omega hydroxylating enzymes in humans: CYP4F3B is the prominent player in PUFA metabolism.

CYP4F2 CYP4F3

8.30e-055101218577768
Pubmed

Replication of interleukin 23 receptor and autophagy-related 16-like 1 association in adult- and pediatric-onset inflammatory bowel disease in Italy.

SLC22A4 SLC22A5

8.30e-055101218698678
Pubmed

Lack of evidence for association of primary sclerosing cholangitis and primary biliary cirrhosis with risk alleles for Crohn's disease in Polish patients.

SLC22A4 SLC22A5

1.24e-046101218715515
Pubmed

Inflammatory response gene polymorphisms and their relationship with colorectal cancer risk.

SLC22A4 SLC22A5

1.24e-046101218433468
Pubmed

Refined genomic localization and ethnic differences observed for the IBD5 association with Crohn's disease.

SLC22A4 SLC22A5

1.24e-046101217213842
Pubmed

The cytochrome P450 4 (CYP4) family.

CYP4F2 CYP4F3

1.24e-04610129068972
Pubmed

Transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous system.

EGR2 EGR3

1.24e-046101237443284
Pubmed

PDZK1 directly regulates the function of organic cation/carnitine transporter OCTN2.

SLC22A4 SLC22A5

1.24e-046101215523054
Pubmed

Egr family members regulate nonlymphoid expression of Fas ligand, TRAIL, and tumor necrosis factor during immune responses.

EGR2 EGR3

1.24e-046101214560009
Pubmed

No association between EGR gene family polymorphisms and schizophrenia in the Chinese population.

EGR2 EGR3

1.24e-046101220144677
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIF26A KDM6B BAHD1 ARHGEF10L METTL14 STAB1 TRIM9 SEMA3E

1.59e-04529101814621295
GeneFamilyRing finger proteins

TRIM58 TRIM23 TRIM9 TRIM17 RNF216 RNF207 PDZRN4

1.11e-0427572758
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF318 ZNF786 PRDM9 ZSCAN10 ZNF394 EGR2 EGR3 ZNF764 ZNF335 ZNF398 ZNF579

1.19e-04718721128
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM58 TRIM23 TRIM9 TRIM17

5.60e-049572459
GeneFamilyHelix-turn-helix CENPB type domain containing

CENPB TIGD6

1.19e-0313722533
GeneFamilyZinc fingers C2HC-type|PHD finger proteins|Lysine acetyltransferases

ZC2HC1B NANOS3

1.81e-031672266
GeneFamilyAnkyrin repeat domain containing

SHANK1 GLS2 ANKRD10 ASAP3 ASB18

2.78e-03242725403
GeneFamilySterile alpha motif domain containing

SHANK1 EPHB6 SFMBT1

5.22e-0388723760
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Myeloid-Microglia|GW16 / Sample Type, Dataset, Time_group, and Cell type.

LPAR5 SIGLEC8 STAB1 EGR2 EGR3 FCGRT ARHGAP45

3.49e-071981017901cd39cb84f1907f2f5d27221979c854bd3b40e
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Myeloid|GW16 / Sample Type, Dataset, Time_group, and Cell type.

LPAR5 SIGLEC8 STAB1 EGR2 EGR3 FCGRT ARHGAP45

3.49e-071981017cc292aa8518d5ef8940e2327f2f07d584a996d90
ToppCellsystemic_lupus_erythematosus-treated-Hematopoietic|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SHANK1 EPHB6 TUT4 AVP SIGLEC8 CPXM1

2.51e-0617010169a18756e6721980d4b6c37bb52ddfe93ca79c5ab
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

PLEKHS1 KDM6B STAB1 JAK3 EGR2 EGR3

2.68e-06172101653dbfe1ac658fd94370cf8e745048cb67fda1daf
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCORL NATD1 MATN1 ASAP3 ARHGEF10L ZNF579

3.60e-0618110164e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCORL NATD1 MATN1 ASAP3 ARHGEF10L ZNF579

3.60e-061811016ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LCORL NATD1 MATN1 ASAP3 ARHGEF10L ZNF579

3.60e-0618110163a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EPOR TRIM58 NATD1 HMBS RIPOR3 SLC22A4

4.08e-061851016c4bf3ac684c1a8876b51f7af4d3a62dc47e961ee
ToppCell10x5'v1-week_17-19-Hematopoietic-erythroid-mid_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EPOR TRIM58 NATD1 HMBS RIPOR3 SLC22A4

4.08e-061851016e9059cefcdf0972ec90793b1dd34c3292b17a061
ToppCellImmune-enucleated_erythrocyte|World / Lineage, Cell type, age group and donor

EPOR TRIM58 NATD1 HMBS RIPOR3 SLC22A4

4.21e-061861016f9d5ec5cc8fd6e63bf25abe390307ec8a4a2d5a3
ToppCellnormal_Lymph_Node-Myeloid_cells-mo-Mac|normal_Lymph_Node / Location, Cell class and cell subclass

SIGLEC8 ACVRL1 ARHGEF10L STAB1 CHST13 FCGRT

4.48e-061881016e83de94a9b47a6a90e98face887eae031a322af6
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TECRL ASB18 MYLK3 RNF207 SBK2 PDZRN4

4.62e-061891016e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCellFetal_29-31_weeks-Immune-enucleated_erythrocyte|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EPOR TRIM58 NATD1 HMBS RIPOR3 SLC22A4

4.62e-0618910161900e574870fc647bfa11c732a72f3d38aab717c
ToppCellMegakaryocytic-erythropoietic-Erythro-cells-Erythrocyte|World / Lineage, cell class and subclass

EPOR TRIM58 NATD1 HMBS RIPOR3 SLC22A4

4.62e-061891016826457adac7477102f86aceb97a8b77929b3e6f9
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TECRL ASB18 MYLK3 RNF207 SBK2 PDZRN4

4.62e-061891016b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCell10x3'2.3-week_12-13-Hematopoietic-erythroid-mid_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

EPOR TRIM58 NATD1 HMBS RIPOR3 SLC22A4

5.21e-0619310161e19f80c52833fb21a8d597a3ba2c4ff464c4559
ToppCell10x3'2.3-week_17-19-Hematopoietic-erythroid-mid_erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EPOR TRIM58 NATD1 HMBS RIPOR3 SLC22A4

5.69e-06196101651c48944149a89b98011a50fe81ca6664d5f0d44
ToppCell10x3'2.3-week_17-19-Hematopoietic-erythroid|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EPOR TRIM58 NATD1 HMBS RIPOR3 SLC22A4

5.86e-061971016b71da7f2fd8d526fb6e5d57e60fc08acdd8dbefb
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LPAR5 SIGLEC8 KDM6B EGR2 EGR3 FCGRT

6.21e-061991016e7faf7d0cb43cf93149c446e5f718f84fa85477c
ToppCellPBMC-Severe-cDC_3|Severe / Compartment, Disease Groups and Clusters

CAPN12 ITPRIPL2 ZNF398 CYP4F3 SEMA3E

2.51e-0515210151a3f8ed476aa9a39742b4684be2c704669e4a3d0
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Tnc|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

LCORL ACVRL1 MYLK3 EGR3 SLC22A4

2.68e-0515410150066b2b8cfc74603e97f271ef5efc7ec512110dc
ToppCellCD8+_Memory_T_cell-RSV-6|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

GLS2 WDR27 SLC22A4 NANOS3 C1QTNF12

3.03e-0515810155ae737757a49fc96bde1e57e02066f9f65654ea1
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-im_megakaryocyte1_(20)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

LPAR5 TRIM58 RIPOR3 MYLK3 ARHGAP45

3.03e-051581015944c5fe625f965dd6153dbcbf5577f99ad343983
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

LPAR5 SIGLEC8 ASAP3 ARHGEF10L ARHGAP45

3.41e-051621015810881210e015c788814e4fe8d7a24c929cf2621
ToppCell15-Distal-Immune-Immune|Distal / Age, Tissue, Lineage and Cell class

CAPN12 LPAR5 TRIM58 RIPOR3 ARHGAP45

3.41e-051621015e190c496ed1e206b86566edfee23c99a99fe90d0
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-erythrocytic|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRIM58 HMBS ESRG ARVCF SLC22A4

4.06e-051681015360cd756067c8cfb6a78301674758eb5fac52c23
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRIM58 HMBS ESRG ARVCF SLC22A4

4.06e-051681015d791116040a9d3ea0485d68c974340116073986b
ToppCellCOVID-19-lung-RBC|COVID-19 / Disease (COVID-19 only), tissue and cell type

LPAR5 TRIM58 HMBS RIPOR3 ARHGAP45

4.92e-0517510154c35292ad2ac712ba7516f27dd6eac6ba8fdd163
ToppCellwk_15-18-Hematologic-Meg-ery-Primitive_erythrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EPOR TRIM58 HMBS RIPOR3 SLC22A4

5.06e-051761015664a7d15563428d0ae156d97aa88415fd0a0506a
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRIM58 NATD1 HMBS RIPOR3 SLC22A4

5.48e-051791015dfefa4b7ae0ee50cf67e0f1938c682f08a03ec53
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-hematologic-erythrocytic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRIM58 NATD1 HMBS RIPOR3 SLC22A4

5.48e-05179101564672528f73ac0921f9c7df72e14ecbfac4d5270
ToppCelldroplet-Spleen-nan-24m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR HMBS OIP5 MYLK3 SLC22A4

5.48e-051791015f3f9c7e575bc4d9d3bce649b90254182e8f6aaec
ToppCelldroplet-Spleen-nan-24m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR HMBS OIP5 MYLK3 SLC22A4

5.48e-05179101501e0b49e7f03ac9c3e6c34708ead300d27236b8b
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-hematologic|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRIM58 NATD1 HMBS RIPOR3 SLC22A4

5.48e-051791015fa0dd87111d399649cdea55f2e610ebc169e8a56
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EPOR MATN1 STAB1 FCGRT UAP1L1

5.48e-051791015fae869fb0a91428481bf8a9c111dcc639e2b4278
ToppCell15-Distal-Epithelial-Epithelial|Distal / Age, Tissue, Lineage and Cell class

TRIM58 RIPOR3 JAK3 EGR3 TRIM9

5.63e-05180101599e2db9ad8e09fedc3542233553acece69f579f1
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIM58 NATD1 HMBS OIP5 ARVCF

5.78e-0518110159dc0563453e24c9d1d975e2e0e1e272487e19908
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Red_blood_cells|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRIM58 NATD1 HMBS RIPOR3 SLC22A4

5.78e-051811015fe2f8b4bd8b09be8ba933529a16e1dca08740dab
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIM58 NATD1 HMBS OIP5 ARVCF

5.78e-05181101514c2dd946e89ba578711c2d25935b6b3d319b701
ToppCellHSPCs-Erythroblasts|World / Lineage and Cell class

EPOR HMBS OIP5 MYLK3 C1QTNF12

5.78e-051811015ce26f1accc8f69b7bc4b929073e975c887566c6a
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIM58 NATD1 HMBS OIP5 ARVCF

5.78e-051811015c5843b89f3d362e236ff76c3279518a2fdfc1f75
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

TRIM58 NATD1 HMBS OIP5 ARVCF

5.78e-051811015fcefb5902416c004631f4f8dd5c8f99fe3bd90bc
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Red_blood_cells-RBC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRIM58 NATD1 HMBS RIPOR3 SLC22A4

5.78e-051811015a16079b1c832456b974d9d06dd1a3eda63ac1bce
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STAB1 CHST13 EGR2 EGR3 RNF216

5.93e-0518210154a85429d365c4b2d73fc921f261b4b7635ac40bd
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STAB1 CHST13 EGR2 EGR3 RNF216

5.93e-05182101553213af34af3337f5edc734d3b7b79e4349eac0d
ToppCell5'-Airway_Nasal-Immune_Myeloid-Myeloid_macrophage-lung_macrophage-Interstitial_macrophage_perivascular-Interstitial_macrophage_perivascular_L.1.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STAB1 CHST13 EGR2 EGR3 RNF216

5.93e-0518210157909089ed6325c44edd6f9b7e8b1d542398222ea
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRIM58 KIF26A NATD1 HMBS RIPOR3

6.09e-051831015b52d7683dc6652766e814ebe935c264ecd610c4b
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-erythrocytic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

TRIM58 KIF26A NATD1 HMBS RIPOR3

6.09e-0518310151d77d8d8c8f78f43dd8864e76f294ee66d4942c2
ToppCellwk_15-18-Hematologic-Meg-ery-Definitive_reticulocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TRIM58 NATD1 HMBS RIPOR3 SLC22A4

6.09e-0518310155470e5ac3439cfc96acd2202f6b1e386779a6637
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid-Micro|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITPRIPL2 LPAR5 SIGLEC8 STAB1 FCGRT

6.25e-051841015371c1927ac06b77ff462a94cca6acb802f9724ff
ToppCellwk_15-18-Hematologic-Meg-ery-Cycling_definitive_erythroblast|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

EPOR TRIM58 HMBS RIPOR3 SLC22A4

6.25e-051841015238eba615b4e04967d44ac7858a6673bdd7f67e9
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITPRIPL2 CENPB SPAG11B EGR2 SEMA3E

6.25e-0518410158fa30789c9d583188667cf375d2218e392dd40bc
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITPRIPL2 LPAR5 SIGLEC8 STAB1 FCGRT

6.25e-051841015fbac70333e4f028bfbdd9cc9401427caac9f0c47
ToppCellBac-SEP-Lymphocyte-T_NK-T_NK_proliferative|Bac-SEP / Disease, Lineage and Cell Type

DTYMK OIP5 ATAD2 TRIM9 CPXM1

6.25e-051841015848d05afd5a2ef61fb8a09c0f5fa2a56fd5c160b
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITPRIPL2 LPAR5 SIGLEC8 STAB1 FCGRT

6.25e-051841015dd6777a0cb49cd79fc439920c3c930a1e4681bb0
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ITPRIPL2 LPAR5 SIGLEC8 STAB1 FCGRT

6.41e-0518510156b832b3e080dfadd21253ac45022192f4d3cb37b
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ITPRIPL2 CENPB SPAG11B EGR2 SEMA3E

6.41e-0518510154bee178ede12f56ba5f5bec44a03dc2a62c50137
ToppCellwk_20-22-Hematologic-Meg-ery-Definitive_reticulocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

EPOR TRIM58 NATD1 HMBS RIPOR3

6.41e-0518510154a2c85e292d4cbce80e92992ded5d66a3aa446ee
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TECRL MYLK3 RNF207 SBK2 PDZRN4

6.57e-051861015337f768cc43db2db96ba6495b076006b1a5b0331
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TECRL MYLK3 RNF207 SBK2 PDZRN4

6.57e-051861015e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-erythro|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TRIM58 NATD1 HMBS RIPOR3 SLC22A4

6.57e-05186101534ed60e846fd83fab3e28dc9e278bcc4b092a9f0
ToppCellwk_08-11-Hematologic-Meg-ery-Definitive_reticulocyte|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TRIM58 NATD1 HMBS RIPOR3 SLC22A4

6.57e-051861015bf8ca7135c05d772aa3f5960b419a13aef3936ae
ToppCellPCW_10-12-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-erythro|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TRIM58 NATD1 HMBS RIPOR3 SLC22A4

6.57e-05186101540acd9b4e9b3c1d1527bd4ba17ae830ff18d6e9d
ToppCellCOVID-19_Mild-Neu_4|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

EPHB6 SFMBT1 TBC1D9B CENPB ATAD2

6.74e-051871015714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCelldroplet-Lung-nan-18m-Myeloid-alveolar_macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPRIPL2 CENPB SPAG11B EGR2 SEMA3E

6.74e-051871015f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCelldroplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPRIPL2 CENPB SPAG11B EGR2 SEMA3E

6.74e-051871015f20e7a1751694390f535ffb27b97e887220f8695
ToppCellwk_08-11-Hematologic-Meg-ery-Cycling_definitive_erythroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

EPOR TRIM58 HMBS RIPOR3 SLC22A4

6.74e-051871015c0965293f08d3e49000871777a5b26d81a4af203
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo-Hem_ErythroMeg|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

EPOR TRIM58 HMBS RIPOR3 SLC22A4

6.91e-0518810155d6faf45a9c0794b0c30b0a0601c10afbb8aa9ed
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

EPOR TRIM58 HMBS RIPOR3 SLC22A4

6.91e-051881015a0873783f0a2cd852563c05a275dddc72905ced2
ToppCellPCW_05-06-Hematologic_ErythroMegGranulo-Hem_ErythroMeg-erythro|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

EPOR TRIM58 HMBS RIPOR3 SLC22A4

6.91e-05188101529d804232d974a8c0029300345b287005b09bade
ToppCellfacs-Heart-LA/RA-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TECRL MYLK3 RNF207 HSPB2 SBK2

7.09e-051891015a08b2d0fa35ffa510050ecffdc68e1b79bbe1632
ToppCellfacs-Heart-LA/RA|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TECRL MYLK3 RNF207 HSPB2 SBK2

7.09e-051891015efa913d9c16fc32166b484d92b6449e8a0c59e03
ToppCelldroplet-Spleen-nan-24m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPOR HMBS OIP5 SLC22A4 C1QTNF12

7.27e-051901015a273fc119baebc11020009c923beafeebb6428c9
ToppCellMegakaryocytic-erythropoietic-Erythro-cells|World / Lineage, cell class and subclass

EPOR TRIM58 HMBS RIPOR3 SLC22A4

7.27e-0519010156c7e016a9b425ee9418acd4fe96b9779fe7bd39a
ToppCell10x3'2.3-week_12-13-Hematopoietic-erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

EPOR TRIM58 HMBS RIPOR3 SLC22A4

7.64e-0519210156ace9a34ed264583042156ed61c2cb3504a331d2
ToppCell10x3'2.3-week_14-16-Hematopoietic-erythroid-mid_erythroid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EPOR TRIM58 HMBS RIPOR3 SLC22A4

8.21e-0519510154759018a7c016cb2e3df5696f1e5f912c7c9ee17
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-Neuronal-GABAergic_neurons|GW12 / Sample Type, Dataset, Time_group, and Cell type.

SHANK1 ESRG ZNF764 ARMC5 PDZRN4

8.21e-051951015efdea22118d5be46c5abfe8e3fbe39503390665d
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

EPOR TRIM58 HMBS RIPOR3 SLC22A4

8.41e-0519610150aae78e73d53416d857bdf21f595a0a0a0ba7944
ToppCell10x3'2.3-week_17-19-Hematopoietic|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

EPOR TRIM58 HMBS RIPOR3 SLC22A4

8.41e-0519610152aeb792e7685e33e3543a6974be790980a41ed8c
ToppCell10x5'v1-week_12-13-Hematopoietic-erythroid-mid_erythroid|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

EPOR TRIM58 HMBS RIPOR3 SLC22A4

8.62e-051971015d8f99a9f2367c8bc9308b0c64d0226875262927a
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

KDM6B EGR2 EGR3 FCGRT ARHGAP45

8.62e-051971015b597c292fc1cb381a4325fed15a32966c38def28
ToppCellTracheal-10x3prime_v2-Epithelial-Epi_airway_ciliated-Deuterosomal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

SFMBT1 ARTN TIGD6 CHST13 SHISA8

8.62e-0519710151ffbbe44db0fd3ebd91ad16ab0b91153de5d7c6d
ToppCellControl_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega|Control_saline / Treatment groups by lineage, cell group, cell type

EPOR TRIM58 HMBS RIPOR3 SLC22A4

8.83e-0519810151a39a98beef68e1e6d3adc25270a3336fcc5baf4
ToppCellControl_saline-Hematopoietic_Erythro-Megakary-Erythro-Mega-Erythroid|Control_saline / Treatment groups by lineage, cell group, cell type

EPOR TRIM58 HMBS RIPOR3 SLC22A4

8.83e-051981015dd80fd9671ee863aebcf4c1023d3e004cc2ee709
ToppCellVE-mono1-|VE / Condition, Cell_class and T cell subcluster

ACVRL1 ARHGEF10L STAB1 EGR2 FCGRT

8.83e-0519810152959d6e4992c36040ec9637f5a2daed02b35cf30
ToppCellVE-mono1|VE / Condition, Cell_class and T cell subcluster

ACVRL1 ARHGEF10L STAB1 EGR2 FCGRT

8.83e-051981015c742871b8ec4720b1848991551c7c1f4000ebd85
ToppCellControl_saline-Hematopoietic_Erythro-Megakary|Control_saline / Treatment groups by lineage, cell group, cell type

EPOR TRIM58 HMBS RIPOR3 SLC22A4

8.83e-051981015cfc2a860bae883299987d3e374d0476ca20e1bdd
ToppCell10x5'v1-week_12-13-Hematopoietic|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

EPOR TRIM58 HMBS RIPOR3 SLC22A4

8.83e-051981015d02e1ff7f68dedaca1e367c7cade772e7b355f45
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SIGLEC8 KDM6B EGR2 EGR3 FCGRT

9.04e-051991015b0a906586e58009f5ed9272fc29ba28e49c85ee6
ToppCell10x5'v1-week_14-16-Hematopoietic-erythroid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EPOR TRIM58 HMBS RIPOR3 SLC22A4

9.04e-0519910158d0eb13a391a2ac1b4f332290c2d00a7fb42bddc
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_-NAF_epineurial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHS1 ACVRL1 BTN2A1 SLC22A5 PDZRN4

9.04e-0519910156f5ef959b51eccf1ffc2e5ddf0d83c62ca2257b2
ToppCell10x5'v1-week_14-16-Hematopoietic-erythroid-mid_erythroid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

EPOR TRIM58 HMBS RIPOR3 SLC22A4

9.04e-051991015e6853b2c0ef6549d5554754c5d5f65825b66025b
ToppCelltumor_Lung-Fibroblasts-COL14A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

ACVRL1 KDM6B EGR2 EGR3 CPXM1

9.04e-0519910150d1f2b0d10c1f8ee10c448659b2a22ea0a6a6f0d
ToppCellParenchymal-NucSeq-Stromal-Peri/Epineurial_|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PLEKHS1 ACVRL1 BTN2A1 SLC22A5 PDZRN4

9.04e-0519910151aa99d21bf61b86df4a966dc47634044430aa39f
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

EPOR TRIM58 NATD1 HMBS OIP5

9.25e-052001015b5f2892bc45fda5ae05e269b840305a608a07c37
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

EPOR TRIM58 NATD1 HMBS OIP5

9.25e-0520010159ce1f91991637fc3af0f6a80a85e1a44276fe412
ToppCellLung_Parenchyma-Severe-Hematopoietic|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

EPOR TRIM58 NATD1 HMBS OIP5

9.25e-052001015fdf3e60cf94f398a56c0fa72813d0459f5ce081b
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-T/NK_proliferative|Bac-SEP / Disease, condition lineage and cell class

DTYMK OIP5 ATAD2 TRIM9 CPXM1

9.25e-052001015a09b4e07b273880e94032b939ab191caaf6d656e
ToppCellLung_Parenchyma-Severe-Hematopoietic-RBC-RBC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EPOR TRIM58 NATD1 HMBS OIP5

9.25e-052001015199165be1aef8497af71b74690a11de18fbe073c
ToppCellParenchyma_COVID-19-Stromal-TX-Erythrocytes|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

EPOR TRIM58 NATD1 HMBS OIP5

9.25e-052001015a9edac2f5e009662df452ec032a80e855cdac28f
Drug5213008; Down 200; 18uM; MCF7; HT_HG-U133A_EA

EPOR OGFOD3 BAHD1 BTN2A1 TRIM23 TIGD6 EGR3 UAP1L1

2.57e-061951018898_DN
Drug0317956-0000 [391210-11-0]; Down 200; 1uM; MCF7; HT_HG-U133A

EPHB6 GLS2 ASAP3 PLEKHS1 ACTL8 ARVCF EGR3

2.40e-0519210173858_DN
DrugBerberine chloride [633-65-8]; Down 200; 10.8uM; MCF7; HT_HG-U133A

EPOR HMBS ARHGEF10L ACTL8 FASTK ZNF335 SLC22A4

2.73e-0519610172770_DN
DrugPanthenol (D) [81-13-0]; Down 200; 19.4uM; MCF7; HT_HG-U133A

EPOR OGFOD3 ARTN BAHD1 TRIM23 ARHGEF10L UAP1L1

2.82e-0519710171680_DN
DrugNaloxone hydrochloride [357-08-4]; Up 200; 11uM; HL60; HG-U133A

EPOR ACVRL1 EGR3 ZNF335 SLC22A4 HEMK1 WDR13

2.92e-0519810172006_UP
Drug2-propylpentanoic acid; Down 200; 50uM; MCF7; HT_HG-U133A

TBC1D9B CENPB ARTN SLC22A5 ARHGAP45 WDR13 NUP160

3.01e-0519910176982_DN
DrugGallamine triethiodide [65-29-2]; Up 200; 4.4uM; HL60; HG-U133A

EGR3 TRIM9 FASTK ZNF764 SLC22A5 PCSK1N HEMK1

3.01e-0519910171375_UP
DrugHydroquinine hydrobromide hydrate [304695-81-6]; Down 200; 9.4uM; PC3; HT_HG-U133A

GLS2 ZNF318 KDM6B TRIM23 ARHGEF10L ARHGAP45 UAP1L1

3.01e-0519910175789_DN
Drugestradiol, USP; Down 200; 0.1uM; MCF7; HT_HG-U133A

TBC1D9B BAHD1 BTN2A1 ARHGEF10L FASTK ZNF335 HEMK1

3.01e-0519910176968_DN
Diseasecarnitine measurement

SFMBT1 ZNF318 SLC22A4 SLC22A5

1.04e-0476944EFO_0010469
DiseaseCoxsackievirus Infections

SLC22A4 SLC22A5

1.49e-046942C0010246
DiseaseMyocarditis

SLC22A4 SLC22A5

1.49e-046942C0027059
DiseaseCarditis

SLC22A4 SLC22A5

1.49e-046942C0869523
Diseaseacetylcarnitine measurement

SLC22A4 SLC22A5

2.78e-048942EFO_0021038
Diseasebutyrylcarnitine measurement

SLC22A4 SLC22A5

2.78e-048942EFO_0020010
Diseasenervonoylcarnitine (C24:1) measurement

SLC22A4 SLC22A5

3.56e-049942EFO_0800549
Diseaseneutrophil count

TRIM58 IQSEC2 WDR27 RIPOR3 ACVRL1 KDM6B ZNF786 ARVCF SLC22A4 SLC22A5 ZNF398 ARHGAP45 NUP160

4.35e-0413829413EFO_0004833
Diseaselignoceroylcarnitine (C24) measurement

SLC22A4 SLC22A5

5.42e-0411942EFO_0800541
Diseasetryptophan betaine measurement

SLC22A4 SLC22A5

6.49e-0412942EFO_0021017
Diseasehexanoylcarnitine measurement

SLC22A4 SLC22A5

6.49e-0412942EFO_0021040
Diseaselymphocyte count

TRIM58 LCORL WDR27 RIPOR3 ARTN ACVRL1 ARVCF EGR2 SLC22A4 SLC22A5 CYP4F3 ARHGAP45 NUP160

7.45e-0414649413EFO_0004587
Diseasehomostachydrine measurement

SLC22A4 SLC22A5

7.65e-0413942EFO_0021164
Diseasedihomo-linolenoylcarnitine (C20:3n3 or 6) measurement

SLC22A4 SLC22A5

7.65e-0413942EFO_0800547
Diseasecerotoylcarnitine (C26) measurement

SLC22A4 SLC22A5

7.65e-0413942EFO_0800542
Diseaseoleoylcarnitine measurement

SLC22A4 SLC22A5

1.66e-0319942EFO_0021043
Diseaseneuroticism measurement

ANKRD10 FAM120AOS ACVRL1 BTN2A1 ARHGEF10L STAB1 ARVCF NUP160 SEMA3E

2.47e-03909949EFO_0007660
Diseasestearoylcarnitine measurement

SLC22A4 SLC22A5

2.65e-0324942EFO_0021045
DiseaseCardiac Arrhythmia

AVP SLC22A5

2.87e-0325942C0003811
DiseaseL lactate dehydrogenase measurement

STAB1 NUP160

3.10e-0326942EFO_0004808

Protein segments in the cluster

PeptideGeneStartEntry
VRSRPCARDAHRKEI

ARHGEF10L

1221

Q9HCE6
VEHRFARRCTPEPQR

ASAP3

536

Q8TDY4
SLRFPLHRACRDGDL

ANKRD10

21

Q9NXR5
HPRAEVRRRACGALR

ARVCF

411

O00192
YARRRVSLGIDICHP

ACTL8

46

Q9H568
FLCHEFLRGNPRVTR

CPXM1

376

Q96SM3
NLHRELCRGRPTEFV

ACVRL1

71

P37023
EVFRLGRPRLAAHCA

ARMC5

871

Q96C12
GEAFHCRLQGPRRVD

C1QTNF12

151

Q5T7M4
DRDPGDRLIRHRACA

ATAD2

1066

Q6PL18
EDAHLRPRAGAARAR

CREG2

81

Q8IUH2
CGATRERAHTRRFCP

NANOS3

96

P60323
VEHCDFGPARRLRSR

PDZRN4

101

Q6ZMN7
GCDRRFSRSDELTRH

EGR2

346

P11161
PSGCLRDFLQRHRAR

JAK3

906

P52333
HFCRDGRVLLGSRAL

FASTK

486

Q14296
SHRRFEGCTPRKCGR

OGFOD3

96

Q6PK18
DLLEARRPRAHECLG

ARHGAP45

141

Q92619
RRPRAHECLGEALRV

ARHGAP45

146

Q92619
RGHLCRTRPTDLVFV

MATN1

31

P21941
RLDRHGFVSREFCRT

HSPB2

106

Q16082
AARVHRPSRCRYRDL

LPAR5

156

Q9H1C0
RRDFCGRPRFLHIRR

HEMK1

321

Q9Y5R4
HFCLGRRRLHLFGRD

METTL14

336

Q9HCE5
GLGHRSDELVRFRFC

ARTN

136

Q5T4W7
GAARRPDEHGRCLRL

ASB18

261

Q6ZVZ8
PGCLECRDFRLRAAH

IQSEC2

576

Q5JU85
SPRCAAERRGFRREL

LCORL

26

Q8N3X6
HRRACKDSVGRRPRE

KDM6B

986

O15054
SCPHRLREHLERGRG

FCGRT

181

P55899
GVAAPRRLRRAADHD

PCSK1N

211

Q9UHG2
DCAARAPVRAEAVRR

MYLK3

461

Q32MK0
IRGAECTERIHRLFG

COG8

91

Q96MW5
SSCEEGRARRPPHLR

KIF26A

741

Q9ULI4
LRHCARKLDPRREGA

GLS2

466

Q9UI32
GCPIRVEHDRRRRQF

NATD1

16

Q8N6N6
RECGRGFRDKSHLLR

PRDM9

751

Q9NQV7
RRDVTRRCCLRPGHY

CAPN12

486

Q6ZSI9
FRRRHGVVSCSGVAR

CENPB

126

P07199
RPDDAIELFNRCRGH

DUSP11

221

O75319
GCDRRFSRSDELTRH

EGR3

281

Q06889
SRAGDPHRSRDRDRA

BAHD1

146

Q8TBE0
PDGQRFRRACRLVHD

CYP4F2

251

P78329
DRRSVRRCPFRHLGE

BTN2A1

346

Q7KYR7
CRLHQAPTARGAVRF

EPOR

91

P19235
PDGQRFRRACRLVHD

CYP4F3

251

Q08477
RRCAIHDIRFSPDSR

EML5

1776

Q05BV3
HERRPVLGCRELVFR

DNAAF5

341

Q86Y56
NHCRDASLISRFRPR

ESRG

156

Q1W209
RCIAERAFLRHLEGG

HMBS

246

P08397
CRRFKLTDFGHTRPR

SBK2

196

P0C263
LRDGREVPHSCSRYR

SLC22A4

71

Q9H015
LRDGREVPHSCRRYR

SLC22A5

71

O76082
PFADAFCVDVRGRRH

ITPRIPL2

231

Q3MIP1
LRHRSRCATPPRGDF

OIP5

6

O43482
LYRLATGCHRRDELP

PUSL1

131

Q8N0Z8
TGCHRRDELPVFERN

PUSL1

136

Q8N0Z8
ERCGLRSVDHRLRLF

STK11IP

781

Q8N1F8
PRDARHCRAFLEELL

STK11IP

891

Q8N1F8
QPLCARCRDETHRAR

RNF207

121

Q6ZRF8
RFRDRHGIALKAVCR

TIGD6

126

Q17RP2
RLPCVRLHAFRDARE

TMEM132E

161

Q6IEE7
LCPGTHYRARVEVRL

RIMBP3

1046

Q9UFD9
RCRDEVHFDPRQRGL

EPHB6

426

O15197
PKRSRRDFGLDCDEH

MSTN

261

O14793
TRCPQRRHGRATFCA

FAM120AOS

71

Q5T036
PRVHVRDEGEFTCRA

SIGLEC8

316

Q9NYZ4
RFCCHDGPRRLDQSR

SHISA8

91

B8ZZ34
GLGSAFLRHIERCRF

MTG2

291

Q9H4K7
RHCRSYDRRALLPAV

RNF216

461

Q9NWF9
PRVRFANDDRHRLAC

WDR13

176

Q9H1Z4
HREARGPSFRICVDF

SPAG11B

76

Q08648
AERERPRHFREFTVC

NUP160

51

Q12769
RTLCLGGAHIDFRAR

SHANK1

231

Q9Y566
RATFRLPRDERLDGH

TBC1D9B

291

Q66K14
RALPDARARGHDVRF

CHST13

211

Q8NET6
ELRDRAPGFRTSDRH

PLEKHS1

406

Q5SXH7
PICSHRERRDAGRRT

ZPLD1

311

Q8TCW7
RLDPARRDFCRESAQ

ZNF394

171

Q53GI3
GSRRRDSDRRPFVCS

ZSCAN10

456

Q96SZ4
RAFARCPPSRAARES

RIPOR3

161

Q96MK2
RRAHASERPFRCAQC

ZNF398

446

Q8TD17
REEPLCNFRGHRGRL

GEMIN5

671

Q8TEQ6
VTEPECREGFHRRAR

AVP

111

P01185
LREHCRRAAEACARP

UAP1L1

46

Q3KQV9
ARCDHFETRPLRLNT

STAB1

1871

Q9NY15
CRESREHRLHRVLPA

TRIM17

121

Q9Y577
CHRSLILDDRGLRGF

TRIM9

131

Q9C026
CGRRFAADVLERHGP

ZC2HC1B

21

Q5TFG8
RHQRIHRPERPFACG

ZNF786

721

Q8N393
FHLESPRSERGRGRC

SEMA3E

156

O15041
DDLRPENHARRSFVC

SFMBT1

311

Q9UHJ3
PCIYDGKESARRLRH

TECRL

166

Q5HYJ1
RTLRCERHFEGHPTR

WDR27

741

A2RRH5
HGRAIRCPFDRQVTD

TRIM23

66

P36406
HDTRDFRDPRDLRCF

TUT4

1346

Q5TAX3
SCPDEHDTLPRRRGR

ZNF335

426

Q9H4Z2
CPECGKGFRRRAHLR

ZNF579

386

Q8NAF0
HFCVSTPERRRLSDR

ZNF318

156

Q5VUA4
STERHIRDRLGRKPC

ZNF861P

51

O60384
PGARRCARHGEDLSR

TRIM58

91

Q8NG06
RGERPHRCLECGRAF

ZNF764

226

Q96H86
CGEPSLHGQRELRRF

KMT2D

71

O14686
CAAGHRAELLRFPER

DTYMK

31

P23919