Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentdendritic spine

SHANK1 SORCS2 DDN ITPKA

7.71e-04242364GO:0043197
GeneOntologyCellularComponentneuron spine

SHANK1 SORCS2 DDN ITPKA

8.33e-04247364GO:0044309
DomainPTPc

PTPN12 PTPRU

2.07e-0336352SM00194
DomainTYR_PHOSPHATASE_PTP

PTPN12 PTPRU

2.42e-0339352PS50055
DomainPTPase_domain

PTPN12 PTPRU

2.67e-0341352IPR000242
DomainY_phosphatase

PTPN12 PTPRU

2.67e-0341352PF00102
DomainPTPc_motif

PTPN12 PTPRU

5.46e-0359352SM00404
DomainTyr_Pase_cat

PTPN12 PTPRU

5.46e-0359352IPR003595
DomainTyr_Pase_AS

PTPN12 PTPRU

8.25e-0373352IPR016130
DomainTYR_PHOSPHATASE_1

PTPN12 PTPRU

1.13e-0286352PS00383
DomainTYR_PHOSPHATASE_2

PTPN12 PTPRU

1.16e-0287352PS50056
DomainTYR_PHOSPHATASE_dom

PTPN12 PTPRU

1.16e-0287352IPR000387
Domain-

PTPN12 PTPRU

1.29e-02923523.90.190.10
DomainProt-tyrosine_phosphatase-like

PTPN12 PTPRU

1.48e-0299352IPR029021
Pubmed

Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.

SHANK1 DDN ATAD3B ITPKA

3.03e-0428140428706196
Pubmed

A mutually stimulating loop involving emx2 and canonical wnt signalling specifically promotes expansion of occipital cortex and hippocampus.

FZD9 ID4

7.93e-043640215800025
Pubmed

Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.

SPATA8 PTPRU

1.03e-034140218951430
Pubmed

OTX2 Transcription Factor Controls Regional Patterning within the Medial Ganglionic Eminence and Regional Identity of the Septum.

ARHGAP22 ID4

1.08e-034240226166575
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SHANK1 SORCS2 ATAD3B IL16 FBXL16 NDUFV2 ITPKA

1.11e-03143140737142655
Cytoband15q15.1

DISP2 ITPKA

7.81e-044740215q15.1
Cytoband16p13.3

PRR35 FBXL16 PRR25

1.27e-0324440316p13.3
Cytoband7q11.23

FZD9 PTPN12

3.27e-03974027q11.23
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ARHGAP22 ZC3H10 AEN KCNAB3

1.07e-05153404991782d111d66e25b40319d4e6dea40f2c2c0805
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

SHANK1 SEMA6C KCNAB3 TMEM151B

1.51e-051674049efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

SHANK1 SEMA6C KCNAB3 TMEM151B

1.51e-05167404904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCellfacs-Marrow-B-cells-24m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR10 MEIS3 DMRT2 KCNAB3

1.69e-0517240465b8935a972bf00b7a10dc2d442128fc0ed78bcb
ToppCellfacs-Marrow-B-cells-24m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCR10 MEIS3 DMRT2 KCNAB3

1.69e-05172404a7fd4d61fb5017dce001d69d6b9a01e6cdf58828
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SHANK1 DISP2 KCNAB3 TMEM151B

2.02e-051804043d54cc767e25d91ed2203d8a03e5bf5e15f21699
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SGPP1 SORCS2 CCDC88C PRR35

2.16e-05183404b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellCerebellum-Neuronal|Cerebellum / BrainAtlas - Mouse McCarroll V32

SHANK1 DISP2 KCNAB3 TMEM151B

2.35e-0518740461b9d6eb131a674598aa8409d7fa909c8765442d
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGPP1 SORCS2 ID4 PRR35

2.60e-051924049e031bf93eb8757fdd0cc22f01b44e48f85532d5
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGPP1 SORCS2 ID4 PRR35

2.60e-051924043d777d07878269b87ec7e1f06489cae7c989d633
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SGPP1 SORCS2 CCDC88C PRR35

2.71e-051944044d6c9b016e3a0641954a8ea10c97d1cd76fadd9f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Degenerative_Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGPP1 SORCS2 ID4 PRR35

2.71e-05194404d602a0cdb69cd5a3e9ef61ddbab8d920557dd73e
Diseasevisceral:abdominal adipose tissue ratio measurement

ID4 DMRT2

2.06e-0352382EFO_0803318
Diseasebehavior

IL16 DMRT2

2.30e-0355382GO_0007610

Protein segments in the cluster

PeptideGeneStartEntry
AGSGSAPCSRRPAPG

AEN

86

Q8WTP8
RGGSCPSGPQPRRGC

CCR10

326

P46092
GPGTPCASRGARLPG

C8orf33

16

Q9H7E9
AGGLRRGCSPPAPAG

FAM117A

21

Q9C073
GSPGCGAARARPEPG

DDN

296

O94850
RPRPGSVGGMPGSCS

DISP2

1146

A7MBM2
SPCPPRPRRGCGDSG

PSMG3-AS1

61

Q96PY0
GPGGSPCLGSERRPK

LIN28B

101

Q6ZN17
KAGSSCQGPGPRSRP

CCDC88C

1866

Q9P219
GRSPSASAGCPGPGI

IL16

651

Q14005
CSPRDGAGAGLGTPP

MEIS3

81

Q99687
PGLGPCGRPASGRLL

PRR25

181

Q96S07
PVRPSGRKAPSGCGG

ID4

6

P47928
SPAPSPAGCGGKGRG

MSL1

66

Q68DK7
SAGCSAPRGPRKGGP

CBFA2T3

36

O75081
GPTGMARPGGARPCS

ITPKA

6

P23677
GGSPRRPCGRKGSPY

PTPRU

851

Q92729
CGGGPKSRAKGSPGP

PRR35

126

P0CG20
PGGRRDCSLPGGSVP

FZD9

491

O00144
GARGPARGGRTPKCT

CAPN12

411

Q6ZSI9
PAGTGPRERCTPAGG

DMRT2

96

Q9Y5R5
PRQGGSIGSGTRPCP

CCDC188

116

H7C350
TGPGSGRSSCQPRKP

PCARE

906

A6NGG8
SSEDRLCGPRPGPGG

KCNAB3

16

O43448
RAALAGGPCTPAGGP

FBXL16

66

Q8N461
GSPPLPFRKCPSGAG

TMEM80

6

Q96HE8
LSICASPRAGPGPGG

TMEM151B

451

Q8IW70
GFGNRCGKPKGPRDP

PTPN12

761

Q05209
CGAAGRSPEPGRLGP

SORCS2

46

Q96PQ0
CPAKPDGGGAPNGVR

SGPP1

76

Q9BX95
RTAPTGPGSRCSPGK

ARHGAP22

406

Q7Z5H3
RACSGPPTAGVAGGP

SHANK1

1801

Q9Y566
GPLSPRMSCGGGRPF

ATAD3B

626

Q5T9A4
RTLAPSLPCPGGRGG

ARMCX1

136

Q9P291
CGSLVVPSGGRPGPA

ZXDC

766

Q2QGD7
TCPCGWRPFKGGPGG

SPATA8

41

Q6RVD6
PSPRPGSCAGVGGAA

SEMA6C

366

Q9H3T2
SRGPRPGPEGCSAGS

TET3

236

O43151
GPKRRRGGCCPPDGP

ZC3H10

206

Q96K80
PGPRSGRFSCEPAGG

NDUFV2

216

P19404