Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptidyltransferase activity

GGT2P GGT1 GGT3P

2.76e-076493GO:0000048
GeneOntologyMolecularFunctionleukotriene-C(4) hydrolase

GGT2P GGT1 GGT3P

2.76e-076493GO:0002951
GeneOntologyMolecularFunctionleukotriene C4 gamma-glutamyl transferase activity

GGT2P GGT1 GGT3P

7.71e-078493GO:0103068
GeneOntologyMolecularFunctionglutathione hydrolase activity

GGT2P GGT1 GGT3P

1.15e-069493GO:0036374
GeneOntologyMolecularFunctionxylose binding

SLC2A14 SLC2A3

5.90e-062492GO:0033222
GeneOntologyMolecularFunctionomega peptidase activity

GGT2P GGT1 GGT3P

7.60e-0616493GO:0008242
GeneOntologyMolecularFunctionthreonine-type peptidase activity

GGT2P GGT1 GGT3P

1.54e-0520493GO:0070003
GeneOntologyMolecularFunctioncatalytic activity, acting on a tRNA

CARS1 TYW1 GGT2P GGT1 GGT3P

2.69e-05144495GO:0140101
GeneOntologyMolecularFunctionmonosaccharide binding

CLEC4D SLC2A14 COLEC10 SLC2A3

8.65e-0595494GO:0048029
GeneOntologyMolecularFunctiongalactose transmembrane transporter activity

SLC2A14 SLC2A3

8.79e-056492GO:0005354
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP6V0A4 ATP2B3 ATP2B4

9.37e-0536493GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP6V0A4 ATP2B3 ATP2B4

9.37e-0536493GO:0015662
GeneOntologyMolecularFunctiondehydroascorbic acid transmembrane transporter activity

SLC2A14 SLC2A3

1.64e-048492GO:0033300
GeneOntologyMolecularFunctiongalactoside binding

SLC2A14 SLC2A3

2.10e-049492GO:0016936
GeneOntologyMolecularFunctionPDZ domain binding

DLGAP3 CLCN3 ATP2B3 ATP2B4

2.34e-04123494GO:0030165
GeneOntologyMolecularFunctionodorant binding

OR8B4 OR10K2 OR8B2 OR8B3

2.65e-04127494GO:0005549
GeneOntologyMolecularFunctionP-type calcium transporter activity

ATP2B3 ATP2B4

3.20e-0411492GO:0005388
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP6V0A4 ATP2B3 ATP2B4

4.74e-0462493GO:0019829
GeneOntologyMolecularFunctionD-glucose binding

SLC2A14 SLC2A3

5.27e-0414492GO:0005536
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

CYC1 ATP6V0A4 ATP2B3 ATP2B4

9.46e-04178494GO:0015399
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

SLC2A14 SLC2A3

1.71e-0325492GO:0055056
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

SLC2A14 SLC2A3

1.71e-0325492GO:0015149
GeneOntologyMolecularFunctionD-mannose binding

CLEC4D COLEC10

1.99e-0327492GO:0005537
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC2A14 SLC2A3

1.99e-0327492GO:0015145
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC2A14 SLC2A3

2.30e-0329492GO:0051119
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP6V0A4 ATP2B3 ATP2B4

2.43e-03109493GO:0042626
GeneOntologyMolecularFunctioncatalytic activity, acting on RNA

CARS1 TYW1 GGT2P GGT1 GGT3P

3.48e-03417495GO:0140098
GeneOntologyMolecularFunctionvitamin transmembrane transporter activity

SLC2A14 SLC2A3

3.52e-0336492GO:0090482
GeneOntologyMolecularFunctionATP-dependent activity

KIF1A MYO7B ATP6V0A4 SMARCA2 ATP2B3 ATP2B4

3.75e-03614496GO:0140657
GeneOntologyMolecularFunctionolfactory receptor activity

OR8B4 OR10K2 OR8B2 OR4K3 OR8B3

4.00e-03431495GO:0004984
GeneOntologyMolecularFunctioncatalytic activity, acting on a nucleic acid

CARS1 SMARCA2 TYW1 GGT2P GGT1 GGT3P

4.77e-03645496GO:0140640
GeneOntologyMolecularFunctioncarbohydrate transmembrane transporter activity

SLC2A14 SLC2A3

4.77e-0342492GO:0015144
GeneOntologyMolecularFunctionhistone deacetylase binding

ZMYND15 MAGEA9 TBX2

5.62e-03147493GO:0042826
GeneOntologyMolecularFunctionactive transmembrane transporter activity

CYC1 CLCN3 ATP6V0A4 ATP2B3 ATP2B4

6.12e-03477495GO:0022804
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

CYC1 ATP6V0A4 ATP2B3 ATP2B4

6.29e-03301494GO:0022853
GeneOntologyMolecularFunctioncarbohydrate binding

CLEC4D SLC2A14 COLEC10 SLC2A3

6.97e-03310494GO:0030246
GeneOntologyBiologicalProcesscysteine biosynthetic process

GGT2P GGT1 GGT3P

7.00e-078493GO:0019344
GeneOntologyBiologicalProcessamino acid metabolic process

AFMID ABAT CARS1 TDO2 ATP2B4 GGT2P GGT1 GGT3P

1.05e-06332498GO:0006520
GeneOntologyBiologicalProcesspeptide modification

GGT2P GGT1 GGT3P

1.49e-0610493GO:0031179
GeneOntologyBiologicalProcessleukotriene D4 biosynthetic process

GGT2P GGT1 GGT3P

1.49e-0610493GO:1901750
GeneOntologyBiologicalProcessamino acid biosynthetic process

ABAT ATP2B4 GGT2P GGT1 GGT3P

1.85e-0686495GO:0008652
GeneOntologyBiologicalProcessglutathione catabolic process

GGT2P GGT1 GGT3P

2.05e-0611493GO:0006751
GeneOntologyBiologicalProcessleukotriene D4 metabolic process

GGT2P GGT1 GGT3P

2.73e-0612493GO:1901748
GeneOntologyBiologicalProcesscysteine metabolic process

GGT2P GGT1 GGT3P

6.90e-0616493GO:0006534
GeneOntologyBiologicalProcessglutathione biosynthetic process

GGT2P GGT1 GGT3P

1.40e-0520493GO:0006750
GeneOntologyBiologicalProcesssulfur amino acid biosynthetic process

GGT2P GGT1 GGT3P

1.63e-0521493GO:0000097
GeneOntologyBiologicalProcessnonribosomal peptide biosynthetic process

GGT2P GGT1 GGT3P

1.88e-0522493GO:0019184
GeneOntologyBiologicalProcessleukotriene biosynthetic process

GGT2P GGT1 GGT3P

1.88e-0522493GO:0019370
GeneOntologyBiologicalProcessalpha-amino acid metabolic process

AFMID TDO2 ATP2B4 GGT2P GGT1 GGT3P

2.76e-05251496GO:1901605
GeneOntologyBiologicalProcessserine family amino acid biosynthetic process

GGT2P GGT1 GGT3P

2.79e-0525493GO:0009070
GeneOntologyBiologicalProcessalpha-amino acid biosynthetic process

ATP2B4 GGT2P GGT1 GGT3P

3.35e-0577494GO:1901607
GeneOntologyBiologicalProcessnon-proteinogenic amino acid metabolic process

AFMID ABAT TDO2 ATP2B4

5.41e-0587494GO:0170041
GeneOntologyBiologicalProcesstryptophan catabolic process to kynurenine

AFMID TDO2

5.50e-055492GO:0019441
GeneOntologyBiologicalProcesspeptide biosynthetic process

GGT2P GGT1 GGT3P

7.16e-0534493GO:0043043
GeneOntologyBiologicalProcessmodified amino acid catabolic process

GGT2P GGT1 GGT3P

9.25e-0537493GO:0042219
GeneOntologyBiologicalProcesssulfur amino acid metabolic process

GGT2P GGT1 GGT3P

1.17e-0440493GO:0000096
GeneOntologyBiologicalProcessleukotriene metabolic process

GGT2P GGT1 GGT3P

1.26e-0441493GO:0006691
GeneOntologyBiologicalProcessserine family amino acid metabolic process

GGT2P GGT1 GGT3P

1.45e-0443493GO:0009069
GeneOntologyBiologicalProcessamino acid catabolic process

AFMID ABAT TDO2 ATP2B4

1.71e-04117494GO:0009063
GeneOntologyBiologicalProcessindole-containing compound catabolic process

AFMID TDO2

1.97e-049492GO:0042436
GeneOntologyBiologicalProcessdehydroascorbic acid transport

SLC2A14 SLC2A3

1.97e-049492GO:0070837
GeneOntologyBiologicalProcesstryptophan catabolic process

AFMID TDO2

1.97e-049492GO:0006569
GeneOntologyBiologicalProcessfatty acid derivative biosynthetic process

GGT2P GGT1 GGT3P

2.57e-0452493GO:1901570
GeneOntologyBiologicalProcessmodified amino acid biosynthetic process

GGT2P GGT1 GGT3P

2.57e-0452493GO:0042398
GeneOntologyBiologicalProcesssulfur compound catabolic process

GGT2P GGT1 GGT3P

2.71e-0453493GO:0044273
GeneOntologyBiologicalProcesskynurenine metabolic process

AFMID TDO2

3.00e-0411492GO:0070189
GeneOntologyBiologicalProcessspermatogenesis

ZMYND15 SPATA31E1 SLC2A14 SMARCA2 ATP2B4 GGT2P GGT1 GGT3P

3.36e-04744498GO:0007283
GeneOntologyBiologicalProcessmale gamete generation

ZMYND15 SPATA31E1 SLC2A14 SMARCA2 ATP2B4 GGT2P GGT1 GGT3P

3.94e-04762498GO:0048232
GeneOntologyBiologicalProcessamine metabolic process

AFMID ABAT TDO2 ATP2B4

4.20e-04148494GO:0009308
GeneOntologyBiologicalProcessglutathione metabolic process

GGT2P GGT1 GGT3P

4.53e-0463493GO:0006749
GeneOntologyBiologicalProcesstryptophan metabolic process

AFMID TDO2

4.94e-0414492GO:0006568
GeneOntologyBiologicalProcessicosanoid biosynthetic process

GGT2P GGT1 GGT3P

5.42e-0467493GO:0046456
GeneOntologyBiologicalProcessurinary tract smooth muscle contraction

ATP2B4 TBX2

5.69e-0415492GO:0014848
GeneOntologyBiologicalProcessproteinogenic amino acid biosynthetic process

GGT2P GGT1 GGT3P

5.91e-0469493GO:0170038
GeneOntologyBiologicalProcessL-amino acid biosynthetic process

GGT2P GGT1 GGT3P

6.17e-0470493GO:0170034
GeneOntologyBiologicalProcessindolalkylamine metabolic process

AFMID TDO2

6.49e-0416492GO:0006586
GeneOntologyBiologicalProcesscarboxylic acid metabolic process

AFMID ABAT HAGHL TDO2 ATP2B4 GGT2P SLC2A3 GGT1 GGT3P

6.52e-041035499GO:0019752
GeneOntologyBiologicalProcessnon-proteinogenic amino acid biosynthetic process

ABAT ATP2B4

7.35e-0417492GO:0170043
GeneOntologyBiologicalProcessoxoacid metabolic process

AFMID ABAT HAGHL TDO2 ATP2B4 GGT2P SLC2A3 GGT1 GGT3P

7.64e-041058499GO:0043436
GeneOntologyBiologicalProcessorganic acid metabolic process

AFMID ABAT HAGHL TDO2 ATP2B4 GGT2P SLC2A3 GGT1 GGT3P

7.95e-041064499GO:0006082
GeneOntologyBiologicalProcessectodermal placode development

TBX2 NRP1

8.26e-0418492GO:0071696
GeneOntologyBiologicalProcesssensory perception

OR8B4 MYO7B ATP6V0A4 OR10K2 ANKRD24 OR8B2 OR4K3 OR8B3 ZNF513

8.39e-041072499GO:0007600
GeneOntologyBiologicalProcessproteinogenic amino acid metabolic process

ATP2B4 GGT2P GGT1 GGT3P

9.69e-04185494GO:0170039
GeneOntologyBiologicalProcessfatty acid derivative metabolic process

GGT2P GGT1 GGT3P

9.78e-0482493GO:1901568
GeneOntologyBiologicalProcesssynaptic vesicle lumen acidification

CLCN3 ATP6V0A4

1.02e-0320492GO:0097401
GeneOntologyBiologicalProcessneuron cellular homeostasis

CLCN3 ATP6V0A4 ATP2B3

1.05e-0384493GO:0070050
GeneOntologyBiologicalProcesspeptide metabolic process

GGT2P GGT1 GGT3P

1.05e-0384493GO:0006518
GeneOntologyBiologicalProcessaromatic amino acid family catabolic process

AFMID TDO2

1.48e-0324492GO:0009074
GeneOntologyBiologicalProcessL-amino acid metabolic process

ATP2B4 GGT2P GGT1 GGT3P

1.49e-03208494GO:0170033
GeneOntologyCellularComponenttransport vesicle membrane

CLCN3 AP1G1 ATP6V0A4 SLC2A14 SLC2A3

5.47e-04293485GO:0030658
GeneOntologyCellularComponentsynaptic vesicle

CLCN3 KIF1A ATP6V0A4 SLC2A14 SLC2A3

6.08e-04300485GO:0008021
GeneOntologyCellularComponentexocytic vesicle membrane

CLCN3 ATP6V0A4 SLC2A14 SLC2A3

7.54e-04179484GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

CLCN3 ATP6V0A4 SLC2A14 SLC2A3

7.54e-04179484GO:0030672
GeneOntologyCellularComponentexocytic vesicle

CLCN3 KIF1A ATP6V0A4 SLC2A14 SLC2A3

8.14e-04320485GO:0070382
GeneOntologyCellularComponentpresynapse

CLCN3 KIF1A AP1G1 ATP6V0A4 SLC2A14 ATP2B3 ATP2B4 SLC2A3

8.44e-04886488GO:0098793
GeneOntologyCellularComponenttransport vesicle

CLCN3 KIF1A AP1G1 ATP6V0A4 SLC2A14 SLC2A3

1.15e-03519486GO:0030133
GeneOntologyCellularComponentsynaptic membrane

CLCN3 SLC2A14 ATP2B3 ATP2B4 SLC2A3 NRP1

2.08e-03583486GO:0097060
GeneOntologyCellularComponentcaveola

SLC2A14 ATP2B4 SLC2A3

2.12e-03111483GO:0005901
GeneOntologyCellularComponentglutamatergic synapse

DLGAP3 CLCN3 SLC2A14 ATP2B3 ATP2B4 SLC2A3 NRP1

2.47e-03817487GO:0098978
MousePhenoabnormal circulating glutathione level

GGT2P GGT1 GGT3P

1.70e-075373MP:0030652
MousePhenoincreased circulating glutathione level

GGT2P GGT1 GGT3P

1.70e-075373MP:0030653
MousePhenoincreased glutathione level

GGT2P GGT1 GGT3P

1.70e-075373MP:0012606
MousePhenoglutathionuria

GGT2P GGT1 GGT3P

1.70e-075373MP:0013730
MousePhenodecreased circulating cysteine level

GGT2P GGT1 GGT3P

5.93e-077373MP:0030626
MousePhenoepididymis hypoplasia

GGT2P GGT1 GGT3P

9.47e-078373MP:0004932
MousePhenodecreased cysteine level

GGT2P GGT1 GGT3P

9.47e-078373MP:0030623
MousePhenonervous

GGT2P GGT1 GGT3P

1.42e-069373MP:0008912
MousePhenofailure of copulatory plug deposition

GGT2P GGT1 GGT3P

2.02e-0610373MP:0030983
MousePhenoseminal vesicle hypoplasia

GGT2P GGT1 GGT3P

2.02e-0610373MP:0005148
MousePhenoovary hypoplasia

GGT2P GGT1 GGT3P

2.02e-0610373MP:0005158
MousePhenoabnormal circulating cysteine level

GGT2P GGT1 GGT3P

2.78e-0611373MP:0030624
MousePhenoabsent tertiary ovarian follicles

GGT2P GGT1 GGT3P

2.78e-0611373MP:0011130
MousePhenoabnormal cysteine level

GGT2P GGT1 GGT3P

4.79e-0613373MP:0030621
MousePhenodecreased glutathione level

GGT2P GGT1 GGT3P

4.79e-0613373MP:0012604
MousePhenoabnormal glutathione level

GGT2P GGT1 GGT3P

4.79e-0613373MP:0012603
MousePhenopriapism

GGT2P GGT1 GGT3P

6.09e-0614373MP:0003415
MousePhenoabnormal copulatory plug deposition

GGT2P GGT1 GGT3P

9.34e-0616373MP:0030982
MousePhenodecreased spleen red pulp amount

GGT2P GGT1 GGT3P

9.34e-0616373MP:0008477
MousePhenodecreased thyroxine level

AP1G1 GGT2P GGT1 GGT3P

9.50e-0651374MP:0005471
MousePhenofailure of superovulation

GGT2P GGT1 GGT3P

1.36e-0518373MP:0031422
MousePhenoabnormal penile erection

GGT2P GGT1 GGT3P

1.36e-0518373MP:0001379
MousePhenooocyte degeneration

GGT2P GGT1 GGT3P

1.36e-0518373MP:0009093
MousePhenoabnormal copulation physiology

GGT2P GGT1 GGT3P

1.61e-0519373MP:0031627
MousePhenoincreased circulating growth hormone level

GGT2P GGT1 GGT3P

1.61e-0519373MP:0005123
MousePhenosmall vertebrae

GGT2P GGT1 GGT3P

2.54e-0522373MP:0004610
MousePhenoabnormal thyroxine level

AP1G1 GGT2P GGT1 GGT3P

2.66e-0566374MP:0005469
MousePhenoincreased growth hormone level

GGT2P GGT1 GGT3P

2.91e-0523373MP:0005137
MousePhenouterus hypoplasia

GGT2P GGT1 GGT3P

2.91e-0523373MP:0001121
MousePhenoabnormal copulation behavior

GGT2P GGT1 GGT3P

3.33e-0524373MP:0009697
MousePhenoabnormal thyroid hormone level

AP1G1 GGT2P GGT1 GGT3P

4.19e-0574374MP:0005468
MousePhenonuclear cataract

GGT2P GGT1 GGT3P

4.26e-0526373MP:0010254
MousePhenoincreased osteoclast cell number

IRAK3 GGT2P GGT1 GGT3P

4.90e-0577374MP:0004984
MousePhenohindlimb paralysis

KIF1A GGT2P GGT1 GGT3P

5.42e-0579374MP:0000755
MousePhenoaminoaciduria

GGT2P GGT1 GGT3P

5.95e-0529373MP:0003311
MousePhenolimb paralysis

KIF1A GGT2P GGT1 GGT3P

6.57e-0583374MP:0013147
MousePhenoanovulation

GGT2P GGT1 GGT3P

8.82e-0533373MP:0008869
MousePhenodecreased circulating follicle stimulating hormone level

GGT2P GGT1 GGT3P

9.65e-0534373MP:0002790
MousePhenodecreased amino acid level

AP1G1 GGT2P GGT1 GGT3P

1.21e-0497374MP:0014528
MousePhenodecreased circulating estradiol level

GGT2P GGT1 GGT3P

1.35e-0438373MP:0005181
MousePhenodecreased tertiary ovarian follicle number

GGT2P GGT1 GGT3P

1.46e-0439373MP:0011129
MousePhenodecreased circulating estrogen level

GGT2P GGT1 GGT3P

1.70e-0441373MP:0003371
MousePhenoinduced hyperactivity

GGT2P GGT1 GGT3P

1.83e-0442373MP:0008911
MousePhenodecreased follicle stimulating hormone level

GGT2P GGT1 GGT3P

2.10e-0444373MP:0005130
MousePhenodecreased long bone epiphyseal plate size

GGT2P GGT1 GGT3P

2.10e-0444373MP:0006396
MousePhenoabsent estrous cycle

GGT2P GGT1 GGT3P

2.10e-0444373MP:0009009
MousePhenoabnormal tertiary ovarian follicle number

GGT2P GGT1 GGT3P

2.55e-0447373MP:0011127
MousePhenoparalysis

KIF1A GGT2P GGT1 GGT3P

2.65e-04119374MP:0000753
MousePhenoabnormal amino acid derivative level

AP1G1 GGT2P GGT1 GGT3P

3.20e-04125374MP:0021145
MousePhenokyphosis

CLCN3 IRAK3 GGT2P GGT1 GGT3P

3.21e-04229375MP:0000160
MousePhenoasthenozoospermia

AP1G1 ATP2B4 TEX44 GGT2P GGT1 GGT3P

3.41e-04362376MP:0002675
MousePhenoabnormal circulating estradiol level

GGT2P GGT1 GGT3P

3.45e-0452373MP:0005183
MousePhenoabnormal osteoclast cell number

IRAK3 GGT2P GGT1 GGT3P

3.51e-04128374MP:0004983
MousePhenoincreased pituitary hormone level

SERPINA6 GGT2P GGT1 GGT3P

3.51e-04128374MP:0003973
MousePhenoaciduria

GGT2P GGT1 GGT3P

4.07e-0455373MP:0010028
MousePhenoabnormal circulating estrogen level

GGT2P GGT1 GGT3P

4.53e-0457373MP:0003369
MousePhenoabnormal tertiary ovarian follicle morphology

GGT2P GGT1 GGT3P

4.53e-0457373MP:0009363
MousePhenodisproportionate dwarf

GGT2P GGT1 GGT3P

4.53e-0457373MP:0002427
MousePhenoabnormal growth hormone level

GGT2P GGT1 GGT3P

4.53e-0457373MP:0003968
MousePhenoabnormal urine amino acid level

GGT2P GGT1 GGT3P

5.01e-0459373MP:0011468
MousePhenoimmotile sperm

GGT2P GGT1 GGT3P

5.01e-0459373MP:0020869
MousePhenodecreased circulating gonadotropin level

GGT2P GGT1 GGT3P

5.26e-0460373MP:0003363
MousePhenodecreased circulating testosterone level

GGT2P GGT1 GGT3P

5.26e-0460373MP:0002780
MousePhenodecreased circulating insulin-like growth factor I level

GGT2P GGT1 GGT3P

5.53e-0461373MP:0004701
MousePhenoimpaired ovarian folliculogenesis

GGT2P GGT1 GGT3P

5.53e-0461373MP:0001129
MousePhenoabnormal sperm motility

AP1G1 ATP2B4 TEX44 GGT2P GGT1 GGT3P

5.87e-04401376MP:0002674
MousePhenoabnormal placental transport

SLC2A14 SLC2A3

6.08e-0414372MP:0004265
MousePhenodiluted coat color

GGT2P GGT1 GGT3P

6.36e-0464373MP:0000371
MousePhenoabnormal superovulation

GGT2P GGT1 GGT3P

6.96e-0466373MP:0009648
MousePhenoabsent corpus luteum

GGT2P GGT1 GGT3P

6.96e-0466373MP:0001134
MousePhenoabnormal long bone epiphyseal plate proliferative zone

GGT2P GGT1 GGT3P

7.60e-0468373MP:0003662
MousePhenosmall epididymis

GGT2P GGT1 GGT3P

8.27e-0470373MP:0004930
MousePhenoincreased macrophage cell number

IRAK3 GGT2P GGT1 GGT3P

8.52e-04162374MP:0005425
MousePhenoabnormal circulating insulin-like growth factor I level

GGT2P GGT1 GGT3P

8.98e-0472373MP:0004700
MousePhenoabnormal insulin-like growth factor I level

GGT2P GGT1 GGT3P

1.01e-0375373MP:0008831
MousePhenoabnormal sixth pharyngeal arch artery morphology

TBX2 NRP1

1.02e-0318372MP:0006355
MousePhenoabnormal sixth pharyngeal arch morphology

TBX2 NRP1

1.02e-0318372MP:0006347
MousePhenoabnormal sperm physiology

AP1G1 ATP2B4 TEX44 GGT2P GGT1 GGT3P

1.04e-03447376MP:0004543
MousePhenoabnormal osteoclast morphology

IRAK3 GGT2P GGT1 GGT3P

1.34e-03183374MP:0004982
MousePhenoabnormal circulating testosterone level

GGT2P GGT1 GGT3P

1.40e-0384373MP:0005180
MousePhenoabnormal circulating androgen level

GGT2P GGT1 GGT3P

1.40e-0384373MP:0009819
MousePhenoabnormal spine curvature

CLCN3 IRAK3 GGT2P GGT1 GGT3P

1.42e-03318375MP:0004174
MousePhenodecreased circulating amino acid level

AP1G1 GGT2P GGT1 GGT3P

1.45e-03187374MP:0014531
MousePhenodecreased circulating pituitary hormone level

GGT2P GGT1 GGT3P

1.66e-0389373MP:0005118
MousePhenoabnormal follicle stimulating hormone level

GGT2P GGT1 GGT3P

1.66e-0389373MP:0003967
MousePhenoabnormal testosterone level

GGT2P GGT1 GGT3P

1.82e-0392373MP:0011385
MousePhenosmall uterus

GGT2P GGT1 GGT3P

1.82e-0392373MP:0002637
MousePhenoabnormal cell motility

AP1G1 NCKIPSD ATP2B4 TEX44 GGT2P GGT1 GGT3P NRP1

1.86e-03885378MP:0020846
MousePhenoabnormal sexual interaction

GGT2P GGT1 GGT3P

1.94e-0394373MP:0002566
MousePhenoabnormal ovulation

GGT2P GGT1 GGT3P

2.12e-0397373MP:0001928
MousePhenoabnormal reproductive system development

GGT2P GGT1 GGT3P

2.25e-0399373MP:0003936
MousePhenodecreased bone mass

GGT2P GGT1 GGT3P

2.31e-03100373MP:0004016
MousePhenostereotypic behavior

CLCN3 AP1G1 ATP6V0A4 ATP2B4

2.37e-03214374MP:0001408
MousePhenoabnormal femur morphology

IRAK3 GGT2P GGT1 GGT3P

2.37e-03214374MP:0000559
MousePhenoabnormal pituitary hormone level

SERPINA6 GGT2P GGT1 GGT3P

2.37e-03214374MP:0003965
MousePhenoabnormal hindlimb stylopod morphology

IRAK3 GGT2P GGT1 GGT3P

2.41e-03215374MP:0003856
MousePhenosmall seminiferous tubules

GGT2P GGT1 GGT3P

2.80e-03107373MP:0001153
MousePhenoincreased circulating pituitary hormone level

GGT2P GGT1 GGT3P

3.03e-03110373MP:0005117
MousePhenoabnormal spleen red pulp morphology

GGT2P GGT1 GGT3P

3.03e-03110373MP:0002356
MousePhenoabnormal seminiferous tubule size

GGT2P GGT1 GGT3P

3.11e-03111373MP:0006307
DomainGlc_transpt_3

SLC2A14 SLC2A3

6.20e-062472IPR002945
DomainATP_Ca_trans_C

ATP2B3 ATP2B4

3.71e-054472IPR022141
DomainP-type_ATPase_IIB

ATP2B3 ATP2B4

3.71e-054472IPR006408
DomainATP_Ca_trans_C

ATP2B3 ATP2B4

3.71e-054472PF12424
DomainGGT_peptidase

GGT1 GGT3P

1.29e-047472IPR000101
DomainG_glu_transpept

GGT1 GGT3P

1.29e-047472PF01019
DomainG_GLU_TRANSPEPTIDASE

GGT1 GGT3P

1.29e-047472PS00462
DomainSugar/inositol_transpt

SLC2A14 SLC2A3

5.53e-0414472IPR003663
Domain-

ATP2B3 ATP2B4

7.27e-04164721.20.1110.10
DomainATPase_P-typ_TM_dom

ATP2B3 ATP2B4

7.27e-0416472IPR023298
DomainSUGAR_TRANSPORT_2

SLC2A14 SLC2A3

8.23e-0417472PS00217
DomainATPase_P-typ_cation-transptr_C

ATP2B3 ATP2B4

8.23e-0417472IPR006068
DomainCation_ATPase_C

ATP2B3 ATP2B4

8.23e-0417472PF00689
DomainCation_ATPase_N

ATP2B3 ATP2B4

9.24e-0418472PF00690
DomainCation_ATPase_N

ATP2B3 ATP2B4

9.24e-0418472SM00831
DomainATPase_P-typ_cation-transptr_N

ATP2B3 ATP2B4

1.03e-0319472IPR004014
DomainSUGAR_TRANSPORT_1

SLC2A14 SLC2A3

1.65e-0324472PS00216
DomainSugar_transporter_CS

SLC2A14 SLC2A3

2.93e-0332472IPR005829
DomainATPase_P-typ_cyto_domN

ATP2B3 ATP2B4

3.50e-0335472IPR023299
DomainSugar_tr

SLC2A14 SLC2A3

3.70e-0336472PF00083
DomainMFS_sugar_transport-like

SLC2A14 SLC2A3

3.70e-0336472IPR005828
DomainATPase_P-typ_P_site

ATP2B3 ATP2B4

3.70e-0336472IPR018303
DomainP_typ_ATPase

ATP2B3 ATP2B4

3.70e-0336472IPR001757
DomainATPASE_E1_E2

ATP2B3 ATP2B4

3.70e-0336472PS00154
DomainATPase_P-typ_transduc_dom_A

ATP2B3 ATP2B4

3.90e-0337472IPR008250
DomainE1-E2_ATPase

ATP2B3 ATP2B4

3.90e-0337472PF00122
DomainFERM_M

MYO7B EPB41L5

5.98e-0346472PF00373
DomainFERM_central

MYO7B EPB41L5

6.76e-0349472IPR019748
DomainFERM_domain

MYO7B EPB41L5

6.76e-0349472IPR000299
Domain-

MYO7B EPB41L5

6.76e-03494721.20.80.10
DomainFERM_1

MYO7B EPB41L5

7.03e-0350472PS00660
DomainFERM_2

MYO7B EPB41L5

7.03e-0350472PS00661
DomainBand_41_domain

MYO7B EPB41L5

7.03e-0350472IPR019749
DomainB41

MYO7B EPB41L5

7.03e-0350472SM00295
DomainFERM/acyl-CoA-bd_prot_3-hlx

MYO7B EPB41L5

7.03e-0350472IPR014352
DomainFERM_3

MYO7B EPB41L5

7.03e-0350472PS50057
PathwayREACTOME_GLUTATHIONE_SYNTHESIS_AND_RECYCLING

GGT2P GGT1 GGT3P

1.16e-0516403MM14680
PathwayWP_EICOSANOID_SYNTHESIS

GGT2P GGT1 GGT3P

3.14e-0522403MM15961
PathwayWP_OXYLIPINS_PATHWAYS

GGT2P GGT1 GGT3P

4.11e-0524403MM17249
PathwayREACTOME_SYNTHESIS_OF_LEUKOTRIENES_LT_AND_EOXINS_EX

GGT2P GGT1 GGT3P

4.66e-0525403MM14858
PathwayREACTOME_AFLATOXIN_ACTIVATION_AND_DETOXIFICATION

GGT2P GGT1 GGT3P

5.26e-0526403MM15190
PathwayWP_GLUTATHIONE_METABOLISM

GGT2P GGT1 GGT3P

5.91e-0527403MM15908
PathwayWP_EICOSANOID_METABOLISM_VIA_LIPOXYGENASES_LOX

GGT2P GGT1 GGT3P

1.09e-0433403MM15963
PathwayWP_GLUTATHIONE_AND_ONECARBON_METABOLISM

GGT2P GGT1 GGT3P

1.30e-0435403MM15815
PathwayWP_VITAMIN_DSENSITIVE_CALCIUM_SIGNALING_IN_DEPRESSION

ATP2B3 ATP2B4 GGT1

1.42e-0436403M39831
PathwayREACTOME_GLUTATHIONE_CONJUGATION

GGT2P GGT1 GGT3P

1.67e-0438403MM14600
PathwayREACTOME_PARACETAMOL_ADME

GGT2P GGT1 GGT3P

1.80e-0439403MM15695
PathwayWP_NAD_BIOSYNTHESIS_II_FROM_TRYPTOPHAN

AFMID TDO2

2.17e-048402M39648
PathwayREACTOME_VITAMIN_C_ASCORBATE_METABOLISM

SLC2A14 SLC2A3

2.79e-049402MM14769
PathwayREACTOME_DRUG_ADME

SERPINA6 GGT2P GGT1 GGT3P

3.49e-04119404MM15692
PathwayBIOCARTA_VITCB_PATHWAY

SLC2A14 SLC2A3

5.09e-0412402MM1526
PathwayREACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS

ATP2B3 ATP2B4

5.09e-0412402M27326
PathwayKEGG_MEDICUS_REFERENCE_NAD_BIOSYNTHESIS

AFMID TDO2

5.09e-0412402M47980
PathwayREACTOME_ARACHIDONIC_ACID_METABOLISM

GGT2P GGT1 GGT3P

6.80e-0461403MM14861
PathwayREACTOME_TRYPTOPHAN_CATABOLISM

AFMID TDO2

6.99e-0414402M1084
PathwayREACTOME_REDUCTION_OF_CYTOSOLIC_CA_LEVELS

ATP2B3 ATP2B4

6.99e-0414402MM15052
PathwayWP_TRYPTOPHAN_CATABOLISM_LEADING_TO_NAD_PRODUCTION

AFMID TDO2

9.19e-0416402M39752
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC2A14 SLC2A3

1.30e-0319402MM14718
PathwayREACTOME_CELLULAR_HEXOSE_TRANSPORT

SLC2A14 SLC2A3

1.59e-0321402M27058
PathwayREACTOME_ION_CHANNEL_TRANSPORT

CLCN3 ATP6V0A4 ATP2B3 ATP2B4

1.74e-03183404M997
PathwayWP_KYNURENINE_PATHWAY_AND_LINKS_TO_CELL_SENESCENCE

AFMID TDO2

2.08e-0324402M40055
PathwayWP_OXIDATIVE_STRESS_AND_REDOX_PATHWAY

GGT2P GGT1 GGT3P

2.23e-0392403MM15823
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ATP2B3 ATP2B4

2.63e-0327402MM15053
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ATP2B3 ATP2B4

2.83e-0328402M924
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

GGT2P GGT1 GGT3P

3.43e-03107403MM14595
PathwayREACTOME_NEUREXINS_AND_NEUROLIGINS

DLGAP3 EPB41L5

3.69e-0332402MM15326
Pubmed

Different gamma-glutamyl transpeptidase mRNAs are expressed in human liver and kidney.

GGT2P GGT1 GGT3P

2.63e-0934932573352
Pubmed

Lung lining fluid glutathione attenuates IL-13-induced asthma.

GGT2P GGT1 GGT3P

2.62e-08549318063838
Pubmed

Gamma-glutamyltranspeptidase knockout mice as a model for understanding the consequences of diminished glutathione on T cell-dependent immune responses.

GGT2P GGT1 GGT3P

2.62e-08549310940879
Pubmed

Liver-Specific Overexpression of Gamma-Glutamyltransferase Ameliorates Insulin Sensitivity of Male C57BL/6 Mice.

GGT2P GGT1 GGT3P

2.62e-08549328660214
Pubmed

Bleomycin-induced pulmonary fibrosis is attenuated in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

2.62e-08549312468440
Pubmed

N-acetyl-cysteine prevents age-related hearing loss and the progressive loss of inner hair cells in γ-glutamyl transferase 1 deficient mice.

GGT2P GGT1 GGT3P

2.62e-08549326977590
Pubmed

Gamma-glutamyl transferase deficiency results in lung oxidant stress in normoxia.

GGT2P GGT1 GGT3P

2.62e-08549312225953
Pubmed

Identification of a sixth promoter that directs the transcription of gamma-glutamyl transpeptidase type III RNA in mouse.

GGT2P GGT1 GGT3P

2.62e-0854937775425
Pubmed

Cataract development in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

2.62e-08549311095909
Pubmed

Expression of gamma-glutamyl transpeptidase in midgestation mouse yolk sac and mouse visceral yolk sac carcinoma cells.

GGT2P GGT1 GGT3P

2.62e-0854937641802
Pubmed

Phenotypic characterization of Ggt1(dwg/dwg) mice,a mouse model for hereditary γ-glutamyltransferase deficiency.

GGT2P GGT1 GGT3P

2.62e-08549323615310
Pubmed

Cloning of cDNA and genomic structure of the mouse gamma-glutamyl transpeptidase-encoding gene.

GGT2P GGT1 GGT3P

2.62e-0854938566783
Pubmed

Therapeutic Effect of GGsTop, Selective Gamma-glutamyl Transpeptidase Inhibitor, on a Mouse Model of 5-Fluorouracil-induced Oral Mucositis.

GGT2P GGT1 GGT3P

2.62e-08549330591459
Pubmed

Mice with genetic gamma-glutamyl transpeptidase deficiency exhibit glutathionuria, severe growth failure, reduced life spans, and infertility.

GGT2P GGT1 GGT3P

2.62e-0854939139708
Pubmed

Analysis of site-specific glycosylation of renal and hepatic γ-glutamyl transpeptidase from normal human tissue.

GGT2P GGT1 GGT3P

2.62e-08549320622017
Pubmed

The mouse skin carcinogenesis model.

GGT2P GGT1 GGT3P

2.62e-0854939627710
Pubmed

Accelerated methylmercury elimination in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

2.62e-0854939546365
Pubmed

Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase.

GGT2P GGT1 GGT3P

2.62e-08549312453183
Pubmed

In vivo reversal of glutathione deficiency and susceptibility to in vivo dexamethasone-induced apoptosis by N-acetylcysteine and L-2-oxothiazolidine-4-carboxylic acid, but not ascorbic acid, in thymocytes from gamma-glutamyltranspeptidase-deficient knockout mice.

GGT2P GGT1 GGT3P

2.62e-08549311795900
Pubmed

gamma-Glutamyl transpeptidase. What does the organization and expression of a multipromoter gene tell us about its functions?

GGT2P GGT1 GGT3P

2.62e-0854937485380
Pubmed

gamma-glutamyltranspeptidase-deficient knockout mice as a model to study the relationship between glutathione status, mitochondrial function, and cellular function.

GGT2P GGT1 GGT3P

2.62e-08549311003618
Pubmed

Accumulation of DNA damage in the organs of mice deficient in gamma-glutamyltranspeptidase.

GGT2P GGT1 GGT3P

2.62e-08549310751614
Pubmed

Gamma-glutamyl transpeptidase gene organization and expression: a comparative analysis in rat, mouse, pig and human species.

GGT2P GGT1 GGT3P

2.62e-08549310392451
Pubmed

Type VI RNA is the major gamma-glutamyl transpeptidase RNA in the mouse small intestine.

GGT2P GGT1 GGT3P

2.62e-0854937523374
Pubmed

Immunocytochemical localization of gamma-glutamyltranspeptidase during fetal development of mouse kidney.

GGT2P GGT1 GGT3P

2.62e-0854932891746
Pubmed

Cardio-reno-hepatic interactions in acute heart failure: the role of γ-glutamyl transferase.

GGT2P GGT1 GGT3P

2.62e-08549324698228
Pubmed

Hyperoxia-induced lung injury in gamma-glutamyl transferase deficiency is associated with alterations in nitrosative and nitrative stress.

GGT2P GGT1 GGT3P

2.62e-08549319850887
Pubmed

Inhibiting lung lining fluid glutathione metabolism with GGsTop as a novel treatment for asthma.

GGT2P GGT1 GGT3P

2.62e-08549325132819
Pubmed

Characterization of the dwg mutations: dwg and dwg(Bayer) are new mutant alleles of the Ggt1 gene.

GGT2P GGT1 GGT3P

2.62e-08549319760322
Pubmed

gamma-Glutamyl transferase (GGT) deficiency in the GGTenu1 mouse results from a single point mutation that leads to a stop codon in the first coding exon of GGT mRNA.

GGT2P GGT1 GGT3P

2.62e-08549310474818
Pubmed

Reversible skeletal abnormalities in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

2.62e-08549312810527
Pubmed

Growth retardation and cysteine deficiency in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

2.62e-0854938755578
Pubmed

Reproductive defects in gamma-glutamyl transpeptidase-deficient mice.

GGT2P GGT1 GGT3P

2.62e-08549311089562
Pubmed

Gamma-glutamyl leukotrienase, a novel endothelial membrane protein, is specifically responsible for leukotriene D(4) formation in vivo.

GGT2P GGT1 GGT3P

5.24e-08649312163373
Pubmed

Gamma-glutamyltranspeptidase stimulates receptor activator of nuclear factor-kappaB ligand expression independent of its enzymatic activity and serves as a pathological bone-resorbing factor.

GGT2P GGT1 GGT3P

5.24e-08649314634009
Pubmed

Overexpression of gamma-glutamyltransferase in transgenic mice accelerates bone resorption and causes osteoporosis.

GGT2P GGT1 GGT3P

5.24e-08649317363454
Pubmed

Six mRNAs with different 5' ends are encoded by a single gamma-glutamyltransferase gene in mouse.

GGT2P GGT1 GGT3P

5.24e-0864938101000
Pubmed

Four distinct membrane-bound dipeptidase RNAs are differentially expressed and show discordant regulation with gamma-glutamyl transpeptidase.

GGT2P GGT1 GGT3P

5.24e-0864938663190
Pubmed

Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes.

GGT2P GGT1 GGT3P

5.24e-0864938104871
Pubmed

Disruption of gamma-glutamyl leukotrienase results in disruption of leukotriene D(4) synthesis in vivo and attenuation of the acute inflammatory response.

GGT2P GGT1 GGT3P

5.24e-08649311463821
Pubmed

Ablation of Mrds1/Ofcc1 induces hyper-γ-glutamyl transpeptidasemia without abnormal head development and schizophrenia-relevant behaviors in mice.

GGT2P GGT1 GGT3P

5.24e-08649322242126
Pubmed

Effect of atorvastatin on the expression of gamma-glutamyl transferase in aortic atherosclerotic plaques of apolipoprotein E-knockout mice.

GGT2P GGT1 GGT3P

5.24e-08649325326709
Pubmed

γ-Glutamyltranspeptidase is an endogenous activator of Toll-like receptor 4-mediated osteoclastogenesis.

GGT2P GGT1 GGT3P

9.16e-08749327775020
Pubmed

Defective epidermal growth factor gene expression in mice with polycystic kidney disease.

GGT2P GGT1 GGT3P

9.16e-0874931968405
Pubmed

Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation.

GGT2P GGT1 GGT3P

9.16e-08749332284594
Pubmed

m6A eraser FTO modulates autophagy by targeting SQSTM1/P62 in the prevention of canagliflozin against renal fibrosis.

GGT2P GGT1 GGT3P

9.16e-08749336685533
Pubmed

Renalase regulates renal dopamine and phosphate metabolism.

GGT2P GGT1 GGT3P

3.13e-071049323863468
Pubmed

The human gamma-glutamyltransferase gene family.

GGT2P GGT1 GGT3P

9.46e-071449318357469
Pubmed

Reprogramming- and pluripotency-associated membrane proteins in mouse stem cells revealed by label-free quantitative proteomics.

SLC2A14 SLC2A3

1.94e-06249223615220
Pubmed

Sex-Specific Life Course Changes in the Neuro-Metabolic Phenotype of Glut3 Null Heterozygous Mice: Ketogenic Diet Ameliorates Electroencephalographic Seizures and Improves Sociability.

SLC2A14 SLC2A3

1.94e-06249228324109
Pubmed

Clinical application value of hepatitis B virus basal core promoter 1762/1764 and GGTII and GGT in patients with HBV-DNA-positive primary liver cancer.

GGT2P GGT1

1.94e-06249237904480
Pubmed

Expression of mouse-GLUT3 and human-GLUT3 glucose transporter proteins in brain.

SLC2A14 SLC2A3

1.94e-0624921734877
Pubmed

Expression of the brain-type glucose transporter is restricted to brain and neuronal cells in mice.

SLC2A14 SLC2A3

1.94e-0624921516757
Pubmed

Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation.

SLC2A14 SLC2A3

1.94e-06249228663252
Pubmed

Gamma glutamyl transferase activity is independently associated with oxidative stress rather than SYNTAX score.

GGT2P GGT1

1.94e-06249225180444
Pubmed

Analysis of the tissue-specific distribution of mRNAs encoding the plasma membrane calcium-pumping ATPases and characterization of an alternately spliced form of PMCA4 at the cDNA and genomic levels.

ATP2B3 ATP2B4

1.94e-0624921531651
Pubmed

Sevoflurane Induces Learning and Memory Impairment in Young Mice Through a Reduction in Neuronal Glucose Transporter 3.

SLC2A14 SLC2A3

1.94e-06249231884568
Pubmed

Adult glut3 homozygous null mice survive to demonstrate neural excitability and altered neurobehavioral responses reminiscent of neurodevelopmental disorders.

SLC2A14 SLC2A3

1.94e-06249233482226
Pubmed

Temporal and spatial distribution of murine placental and brain GLUT3-luciferase transgene as a readout of in vivo transcription.

SLC2A14 SLC2A3

1.94e-06249223193055
Pubmed

Neuronal glucose transporter isoform 3 deficient mice demonstrate features of autism spectrum disorders.

SLC2A14 SLC2A3

1.94e-06249219506559
Pubmed

Human GGT2 does not autocleave into a functional enzyme: A cautionary tale for interpretation of microarray data on redox signaling.

GGT2P GGT1

1.94e-06249223682772
Pubmed

Gene expression of GLUT3 glucose transporter regulated by glucose in vivo in mouse brain and in vitro in neuronal cell cultures from rat embryos.

SLC2A14 SLC2A3

1.94e-0624928198523
Pubmed

Identification of gene markers for the prediction of allograft rejection or permanent acceptance.

MAN1A1 TCAIM

1.94e-06249217456197
Pubmed

Copy-Number Variation of the Glucose Transporter Gene SLC2A3 and Congenital Heart Defects in the 22q11.2 Deletion Syndrome.

SLC2A14 SLC2A3

1.94e-06249225892112
Pubmed

CD205+ polymorphonuclear myeloid-derived suppressor cells suppress antitumor immunity by overexpressing GLUT3.

SLC2A14 SLC2A3

1.94e-06249233368883
Pubmed

Glucose Transporter 3 is Essential for the Survival of Breast Cancer Cells in the Brain.

SLC2A14 SLC2A3

1.94e-06249231817208
Pubmed

Brain glucose transporter (Glut3) haploinsufficiency does not impair mouse brain glucose uptake.

SLC2A14 SLC2A3

1.94e-06249221316350
Pubmed

Neuronal functions, feeding behavior, and energy balance in Slc2a3+/- mice.

SLC2A14 SLC2A3

1.94e-06249218780771
Pubmed

Canine brain glucose transporter 3: gene sequence, phylogenetic comparisons and analysis of functional sites.

SLC2A14 SLC2A3

1.94e-0624928654954
Pubmed

Altered lactate metabolism in Huntington's disease is dependent on GLUT3 expression.

SLC2A14 SLC2A3

1.94e-06249229582588
Pubmed

Association between serum γ-glutamyltranspeptidase and atherosclerosis: a population-based cross-sectional study.

GGT2P GGT1

1.94e-06249225280803
Pubmed

Placental glucose and amino acid transport in calorie-restricted wild-type and Glut3 null heterozygous mice.

SLC2A14 SLC2A3

1.94e-06249222700768
Pubmed

Glucose transporter isoform-3-null heterozygous mutation causes sexually dimorphic adiposity with insulin resistance.

SLC2A14 SLC2A3

1.94e-06249218445753
Pubmed

Gene dosage in the developing and adult brain in a mouse model of 22q11 deletion syndrome.

GGT2P GGT1 GGT3P

2.11e-061849317097888
Pubmed

Glucose transporter isoform-3 mutations cause early pregnancy loss and fetal growth restriction.

SLC2A14 SLC2A3

5.83e-06349217213475
Pubmed

NFκB up-regulation of glucose transporter 3 is essential for hyperactive mammalian target of rapamycin-induced aerobic glycolysis and tumor growth.

SLC2A14 SLC2A3

5.83e-06349225578782
Pubmed

Gestational changes of glucose transporter gene expression in the mouse placenta and decidua.

SLC2A14 SLC2A3

5.83e-0634928905482
Pubmed

Regular Exercise Enhances Cognitive Function and Intracephalic GLUT Expression in Alzheimer's Disease Model Mice.

SLC2A14 SLC2A3

5.83e-06349231561359
Pubmed

Calpain I Activation Causes GLUT3 Proteolysis and Downregulation of O-GlcNAcylation in Alzheimer's Disease Brain.

SLC2A14 SLC2A3

5.83e-06349229614685
Pubmed

High NOV/CCN3 expression during high-fat diet pregnancy in mice affects GLUT3 expression and the mTOR pathway.

SLC2A14 SLC2A3

5.83e-06349233586490
Pubmed

Hyperglycemia reduces mitochondrial content and glucose transporter expression in mouse embryos developing in vitro.

SLC2A14 SLC2A3

5.83e-06349219550108
Pubmed

LPCAT1 Facilitates Keratinocyte Hyperproliferation and Skin Inflammation in Psoriasis by Regulating GLUT3.

SLC2A14 SLC2A3

5.83e-06349238246582
Pubmed

Placental glucose transporter expression is regulated by glucocorticoids.

SLC2A14 SLC2A3

5.83e-06349210199793
Pubmed

Glucose transporter GLUT3: ontogeny, targeting, and role in the mouse blastocyst.

SLC2A14 SLC2A3

5.83e-0634929108057
Pubmed

Glucose transporter proteins in brain.

SLC2A14 SLC2A3

5.83e-0634927926364
Pubmed

Recurrent moderate hypoglycemia accelerates the progression of Alzheimer's disease through impairment of the TRPC6/GLUT3 pathway.

SLC2A14 SLC2A3

5.83e-06349235077394
Pubmed

Molecular cloning of murine homologue dentatorubral-pallidoluysian atrophy (DRPLA) cDNA: strong conservation of a polymorphic CAG repeat in the murine gene.

SLC2A14 SLC2A3

5.83e-0634929070948
Pubmed

Significant reduction of the GLUT3 level, but not GLUT1 level, was observed in the brain tissues of several scrapie experimental animals and scrapie-infected cell lines.

SLC2A14 SLC2A3

5.83e-06349224243341
Pubmed

Vitamin C enters mouse T cells as dehydroascorbic acid in vitro and does not recapitulate in vivo vitamin C effects.

SLC2A14 SLC2A3

5.83e-06349219327547
Pubmed

Glucose Metabolism Is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes.

SLC2A14 SLC2A3

5.83e-06349230765335
Pubmed

Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function.

SLC2A14 SLC2A3

5.83e-06349228746873
Pubmed

Glucose transporter expression in brain. cDNA sequence of mouse GLUT3, the brain facilitative glucose transporter isoform, and identification of sites of expression by in situ hybridization.

SLC2A14 SLC2A3

5.83e-0634921730609
Pubmed

Evidence for a family of human glucose transporter-like proteins. Sequence and gene localization of a protein expressed in fetal skeletal muscle and other tissues.

SLC2A14 SLC2A3

5.83e-0634923170580
Pubmed

Hepatoblast-like cells enriched from mouse embryonic stem cells in medium without glucose, pyruvate, arginine, and tyrosine.

GGT2P GGT1 GGT3P

7.51e-062749318478268
Pubmed

Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells.

GGT2P GGT1 GGT3P

9.36e-062949322424930
Pubmed

Difference in allelic expression of genes probably associated with tumor progression in murine fibrosarcomas and cell lines.

SLC2A14 SLC2A3

1.16e-0544927961103
Pubmed

Structural organization, ion transport, and energy transduction of P-type ATPases.

ATP2B3 ATP2B4

1.16e-0544928634322
Pubmed

Developmental regulation of genes mediating murine brain glucose uptake.

SLC2A14 SLC2A3

1.16e-05449210070152
Pubmed

Cytoprotective effects of hesperetin and hesperidin against amyloid β-induced impairment of glucose transport through downregulation of neuronal autophagy.

SLC2A14 SLC2A3

1.16e-05449222383310
Pubmed

Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.

ATP2B3 ATP2B4

1.16e-05449212209837
InteractionGGT2P interactions

GGT2P GGT1

1.46e-053452int:GGT2P
InteractionNR1D1 interactions

INPP1 TDO2 HUWE1

2.31e-0525453int:NR1D1
CytobandEnsembl 112 genes in cytogenetic band chr11q24

OR8B4 OR8B2 OR8B3

1.13e-03191493chr11q24
Cytoband11q24.2

OR8B4 OR8B3

2.09e-036349211q24.2
Cytoband12p13.31

CLEC4D SLC2A14

3.34e-038049212p13.31
GeneFamilyCD molecules|Gamma-glutamyltransferases

GGT2P GGT1 GGT3P

1.72e-0613343564
GeneFamilyOlfactory receptors, family 8

OR8B4 OR8B2 OR8B3

1.06e-0449343155
GeneFamilyATPases Ca2+ transporting

ATP2B3 ATP2B4

1.23e-0493421209
GeneFamilyAnkyrin repeat domain containing|FERM domain containing

MYO7B EPB41L5

3.97e-03503421293
GeneFamilyADAM metallopeptidase domain containing|CD molecules

CLEC4D TNFRSF18 GGT1 NRP1

6.14e-03394344471
CoexpressionGSE20366_TREG_VS_NAIVE_CD4_TCELL_HOMEOSTATIC_CONVERSION_UP

DLGAP3 MAN1A1 ZBTB32 TNFRSF18 ATP2B4 SLC2A3

1.33e-06200466M4330
CoexpressionGAVIN_FOXP3_TARGETS_CLUSTER_P3

SLC2A14 GGT2P SLC2A3 GGT1 GGT3P

1.30e-05173465MM725
CoexpressionGSE4535_BM_DERIVED_DC_VS_FOLLICULAR_DC_DN

AFMID MAN1A1 AP1G1 SMARCA2 GGT1

2.62e-05200465M6574
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_THEMIS_PLA2G7|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

OR8B4 TDO2 OR8B2 OR8B3 NRP1

1.28e-061724951d086e00cd549459d70e1d3b468d5ab6379f3bee
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATP6V0A4 TNFRSF18 ATP2B3 TBX2

1.71e-05140494e64f6aa57bc069cfe970089bd1c298433bfaf771
ToppCellB_cells-Naive_B_cells_|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

ABAT MYO7B IRAK3 SLC2A3

4.37e-0517849471ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

AFMID ABAT MYO7B NRP1

4.46e-05179494d1ef7e1cb00336118e387b47f4f8120f53584391
ToppCellRA-07._Pericyte|World / Chamber and Cluster_Paper

DLGAP3 ADAMTS4 TBX2 NRP1

4.76e-051824942075efeae633550fb2eb026d0dfd741c8252482e
ToppCellcellseq2-Immune-Hematopoietic-Granulocytic-Neutrophil|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CLEC4D MYO7B IRAK3 SLC2A3

4.76e-051824941932d77491d6d46278f01fd70eb469ef1b356619
ToppCellcellseq2-Immune-Hematopoietic-Granulocytic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CLEC4D MYO7B IRAK3 SLC2A3

4.86e-05183494cfbf8539104cef9ca830ad4f6bb278746f7078f7
ToppCellcellseq2-Immune-Hematopoietic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CLEC4D MYO7B IRAK3 SLC2A3

4.86e-05183494324ec4374b552da7ce03809945b3a0798342d4ba
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B1_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZMYND15 ABAT KIF1A TBX2

5.07e-05185494ef996f4cdbc3971c6c0460d13df64b075ab22154
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ZMYND15 ABAT KIF1A TBX2

5.07e-05185494d51342a3979bd728a80e04126059a3fd8a0dbe3b
ToppCellPCW_13-14|World / Celltypes from embryonic and fetal-stage human lung

SMARCA2 IRAK3 TBX2 NRP1

5.63e-0519049462a3ec1ae0829602b0569cc051210551644f1d46
ToppCell10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3|lymph-node_spleen / Manually curated celltypes from each tissue

IRAK3 TNFRSF18 TBX2 NRP1

5.86e-05192494e16035b3328f9b1b2e28d234c62ba88387540550
ToppCellCV-Moderate-6|CV / Virus stimulation, Condition and Cluster

ZBTB32 SMARCA2 HUWE1 SLC2A3

6.35e-051964947bced0cc2112697593c478fa291b8ed3941fb811
ToppCelldistal-2-Endothelial-Capillary_Aerocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

INPP1 COLEC10 ATP2B4 TBX2

6.73e-05199494bf70c8bfe932bccac5014e55f82019c5148627e7
ToppCelldistal-Endothelial-Capillary_Aerocyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

INPP1 COLEC10 ATP2B4 TBX2

6.73e-051994949021f4be004efd51bb3658e5bbff53589356b3df
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuroepithelial|GW26 / Sample Type, Dataset, Time_group, and Cell type.

SLC2A14 TDO2 GGT1 TBX2

6.86e-052004948b80811a0ec28d1d763c10b095d1969bccbe82d4
ToppCellParenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

INPP1 COLEC10 TBX2 NRP1

6.86e-052004943653002c805c314043e2a7b0c9980dfe952dc53e
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary-EC_aerocyte_capillary_L.2.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INPP1 COLEC10 TBX2 NRP1

6.86e-052004943767abc75176779198505ebc6967d55ce322d9fe
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuroepithelial-Proteoglycan-expressing_cell|GW26 / Sample Type, Dataset, Time_group, and Cell type.

SLC2A14 TDO2 GGT1 TBX2

6.86e-0520049452ec80f3922ae6ee3565d5993c2fc56bb3a3199a
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_aerocyte_capillary|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

INPP1 COLEC10 TBX2 NRP1

6.86e-05200494e0a003d2a5fd6adfcb817c9bc5dceb9c79e7491b
ToppCellTracheal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 TDO2 SLC2A3 TBX2

6.86e-0520049478cd0b7d221ef855512ee9ac9a291f61622c2e24
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Metaplastic_Carcinoma-9|TCGA-Breast / Sample_Type by Project: Shred V9

OR8B4 OR8B2 OR8B3

8.07e-05764933d0e3ddac63e805cfa1552ccedeff777aec9d05f
Diseaseaflatoxins-related hepatocellular carcinoma (biomarker_via_orthology)

GGT2P GGT1 GGT3P

1.41e-077483DOID:5022 (biomarker_via_orthology)
Diseasealcohol dependence (biomarker_via_orthology)

GGT2P GGT1 GGT3P

2.25e-078483DOID:0050741 (biomarker_via_orthology)
DiseaseHailey-Hailey disease (implicated_via_orthology)

ATP2B3 ATP2B4

3.87e-056482DOID:0050429 (implicated_via_orthology)
Diseasecataract (biomarker_via_orthology)

SLC2A14 SLC2A3

2.00e-0413482DOID:83 (biomarker_via_orthology)
Diseasebanks of the superior temporal sulcus volume measurement

AP1G1 SMARCA2

3.47e-0417482EFO_0010286
DiseaseAutistic Disorder

ABAT KIF1A INPP1 TDO2

8.57e-04261484C0004352
Diseasediabetes mellitus (is_marker_for)

SLC2A3 GGT1

2.04e-0341482DOID:9351 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
ESLTHCRIRGGMLAM

COLEC10

171

Q9Y6Z7
MLAAGGAGLAMALHS

CYC1

66

P08574
MRGAASCLEVMIAHG

ANKRD24

91

Q8TF21
LLSGTHVMEGSGRMV

ATP2B3

261

Q16720
LLSGTHVMEGSGRMV

ATP2B4

256

P23634
TGACGHSRRGMRMTC

HAGHL

231

Q6PII5
CGHSAGAHLAAMMLL

AFMID

161

Q63HM1
GFAGAMAHTGSMLRL

OR8B4

151

Q96RC9
LGCMGSSEMCRDLAG

AP1G1

126

O43747
ALLCVGLMNAHSMGI

GGT3P

71

A6NGU5
DSCAAHAILRAMGGG

INPP1

316

P49441
LGLSCDSMLGDGHSM

MAGEA9

181

P43362
LSFMGAFHGRTMGCL

ABAT

211

P80404
GCMTQMFFLHLLGGA

OR4K3

96

Q96R72
MAGNCGARGALSAHT

IRAK3

1

Q9Y616
MGLAGATAHTGCMLR

OR8B3

151

Q8NGG8
RTLHMIGLGGMAFCS

SLC2A14

356

Q8TDB8
GGRMAESMLAILCHI

HUWE1

1266

Q7Z6Z7
CSGMLGMVSGLISDS

NRP1

431

O14786
GPAQACMGGRCLHMD

ADAMTS4

496

O75173
GAMSNGLAGCEMLLT

EPB41L5

671

Q9HCM4
FAGSNSHAMCILMGL

BNIP5

611

P0C671
GGSEGRCLACTGMSM

DLGAP3

306

O95886
MGHLTCFAGGMFALG

MAN1A1

471

P33908
RRTLHMIGLGGMAFC

SLC2A3

331

P11169
GGTMGQASAHILCRR

ELP5

191

Q8TE02
SMALAMLSLGTCGHT

SERPINA6

71

P08185
ALLCVGLMNAHSMGI

GGT2P

71

P36268
DHRGGMPCMGTFLLH

KIF1A

1156

Q12756
MGLAGATAHTGCMLR

OR8B2

151

Q96RD0
RYSVLMGHGVCMGLV

OR10K2

131

Q6IF99
MGHGVCMGLVAAACA

OR10K2

136

Q6IF99
TDRSGMSAVGHVMLG

TCAIM

271

Q8N3R3
MAGTLLGASMDIHGG

CARS1

351

P49589
VEDIHCGSMKGTGMR

SMARCA2

86

P51531
MVHRMLGSKAGTGGS

TDO2

331

P48775
TGLCLPGRHMDMLTA

SPATA31E1

1126

Q6ZUB1
REALMASGSGGHNTM

NCKIPSD

191

Q9NZQ3
AESERNCSGMGAHLM

CLEC4D

106

Q8WXI8
MVGAAACLGGVTRMT

CLCN3

576

P51790
MGMAIATGFLDSGHS

TEX44

301

Q53QW1
GEGSRLGAAMCGRCM

ZNF513

326

Q8N8E2
LGAAMCGRCMRGEAG

ZNF513

331

Q8N8E2
GAFSAMGMGHLLASV

TBX2

501

Q13207
MAQHGAMGAFRALCG

TNFRSF18

1

Q9Y5U5
AVMFGDCGHGTVMLL

ATP6V0A4

406

Q9HBG4
GCPSLASMQAHMRGH

ZBTB32

436

Q9Y2Y4
MLGAHRVMSRGEGDC

TYW1

201

Q9NV66
ALLCHSMACPMGSGD

ZMYND15

246

Q9H091
ALLCVGLMNAHSMGI

GGT1

71

P19440
LGSGRDHMMDAIARC

MYO7B

1251

Q6PIF6