Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	EGF_1	RELN NOTCH2NLA NRG2 LAMA5 NOTCH2NLC ITGB1 LRP1B MEP1B HEG1 FBN2 SCUBE2 LRP1 MUC3A	2.45e-09	255	107	13	PS00022
Domain	EGF-like_CS	RELN NOTCH2NLA NRG2 LAMA5 NOTCH2NLC ITGB1 LRP1B MEP1B HEG1 FBN2 SCUBE2 LRP1 MUC3A	3.24e-09	261	107	13	IPR013032
Domain	EGF	RELN NOTCH2NLA NRG2 LAMA5 NOTCH2NLC LRP1B MEP1B HEG1 FBN2 SCUBE2 LRP1 MUC3A	1.03e-08	235	107	12	SM00181
Domain	EGF-like_dom	RELN NOTCH2NLA NRG2 LAMA5 NOTCH2NLC LRP1B MEP1B HEG1 FBN2 SCUBE2 LRP1 MUC3A	1.96e-08	249	107	12	IPR000742
Domain	EGF_2	RELN NOTCH2NLA NRG2 LAMA5 NOTCH2NLC LRP1B MEP1B HEG1 FBN2 SCUBE2 LRP1 MUC3A	3.90e-08	265	107	12	PS01186
Domain	EGF_3	RELN NOTCH2NLA NRG2 NOTCH2NLC LRP1B MEP1B HEG1 FBN2 SCUBE2 LRP1 MUC3A	1.06e-07	235	107	11	PS50026
Domain	EGF_CA	NOTCH2NLA NOTCH2NLC LRP1B HEG1 FBN2 SCUBE2 LRP1	6.16e-07	86	107	7	PF07645
Domain	EGF	NOTCH2NLA NRG2 NOTCH2NLC LRP1B MEP1B HEG1 SCUBE2 LRP1	6.40e-07	126	107	8	PF00008
Domain	EGF_Ca-bd_CS	NOTCH2NLA NOTCH2NLC LRP1B HEG1 FBN2 SCUBE2 LRP1	1.40e-06	97	107	7	IPR018097
Domain	EGF_CA	NOTCH2NLA NOTCH2NLC LRP1B HEG1 FBN2 SCUBE2 LRP1	1.60e-06	99	107	7	PS01187
Domain	ASX_HYDROXYL	NOTCH2NLA NOTCH2NLC LRP1B HEG1 FBN2 SCUBE2 LRP1	1.72e-06	100	107	7	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	NOTCH2NLA NOTCH2NLC LRP1B HEG1 FBN2 SCUBE2 LRP1	2.54e-06	106	107	7	IPR000152
Domain	EGF_CA	NOTCH2NLA NOTCH2NLC LRP1B HEG1 FBN2 SCUBE2 LRP1	6.48e-06	122	107	7	SM00179
Domain	EGF-like_Ca-bd_dom	NOTCH2NLA NOTCH2NLC LRP1B HEG1 FBN2 SCUBE2 LRP1	7.22e-06	124	107	7	IPR001881
Domain	cEGF	LRP1B FBN2 SCUBE2 LRP1	1.38e-05	26	107	4	PF12662
Domain	cEGF	LRP1B FBN2 SCUBE2 LRP1	1.38e-05	26	107	4	IPR026823
Domain	DUF5050	LRP1B LRP1	3.25e-05	2	107	2	IPR032485
Domain	DUF5050	LRP1B LRP1	3.25e-05	2	107	2	PF16472
Domain	Growth_fac_rcpt_	TMEM67 LAMA5 LRP1B FBN2 SCUBE2 LRP1	2.78e-04	156	107	6	IPR009030
Domain	KAP	KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	3.41e-04	58	107	4	IPR002494
Domain	RNaseA_AS	RNASE8 RNASE7	8.90e-04	8	107	2	IPR023411
Domain	RNASE_PANCREATIC	RNASE8 RNASE7	8.90e-04	8	107	2	PS00127
Domain	Keratin_B2_2	KRTAP10-1 KRTAP10-8 KRTAP10-3	1.44e-03	39	107	3	PF13885
Domain	Keratin_B2	KRTAP10-1 KRTAP10-5 KRTAP10-3	1.55e-03	40	107	3	PF01500
Domain	Ephrin_rec_like	TG SCUBE2	1.73e-03	11	107	2	PF07699
Domain	RNAse_Pc	RNASE8 RNASE7	1.73e-03	11	107	2	SM00092
Domain	MATH	TRAF3 MEP1B	2.07e-03	12	107	2	PS50144
Domain	MATH/TRAF_dom	TRAF3 MEP1B	2.07e-03	12	107	2	IPR002083
Domain	MATH	TRAF3 MEP1B	2.07e-03	12	107	2	SM00061
Domain	MATH	TRAF3 MEP1B	2.07e-03	12	107	2	PF00917
Domain	6-blade_b-propeller_TolB-like	LRP1B TECPR2 LRP1	2.32e-03	46	107	3	IPR011042
Domain	RNaseA	RNASE8 RNASE7	2.43e-03	13	107	2	PD000535
Domain	-	TRAF3 MEP1B	2.83e-03	14	107	2	2.60.210.10
Domain	PLAC	ADAMTS10 ADAMTS6	2.83e-03	14	107	2	PF08686
Domain	Ldl_recept_b	LRP1B LRP1	2.83e-03	14	107	2	PF00058
Domain	LDLRB	LRP1B LRP1	2.83e-03	14	107	2	PS51120
Domain	RNaseA	RNASE8 RNASE7	3.25e-03	15	107	2	IPR001427
Domain	RNaseA_domain	RNASE8 RNASE7	3.25e-03	15	107	2	IPR023412
Domain	-	RNASE8 RNASE7	3.25e-03	15	107	2	3.10.130.10
Domain	LY	LRP1B LRP1	3.25e-03	15	107	2	SM00135
Domain	RnaseA	RNASE8 RNASE7	3.25e-03	15	107	2	PF00074
Domain	LDLR_classB_rpt	LRP1B LRP1	3.25e-03	15	107	2	IPR000033
Domain	CY	CSTL1 FETUB	4.18e-03	17	107	2	SM00043
Domain	-	TRAF3 SPIRE2 MARCHF7 KMT2E ZFYVE1 EEA1 TRIM49B USP3	4.30e-03	449	107	8	3.30.40.10
Domain	Cystatin_dom	CSTL1 FETUB	4.69e-03	18	107	2	IPR000010
Domain	Cystatin	CSTL1 FETUB	4.69e-03	18	107	2	PF00031
Domain	Znf_RING/FYVE/PHD	TRAF3 SPIRE2 MARCHF7 KMT2E ZFYVE1 EEA1 TRIM49B USP3	4.90e-03	459	107	8	IPR013083
Domain	EGF_extracell	RELN ITGB1 LRP1B	4.94e-03	60	107	3	IPR013111
Domain	EGF_2	RELN ITGB1 LRP1B	4.94e-03	60	107	3	PF07974
Domain	PLAC	ADAMTS10 ADAMTS6	5.22e-03	19	107	2	PS50900
Domain	PLAC	ADAMTS10 ADAMTS6	5.22e-03	19	107	2	IPR010909
Domain	UPAR_LY6	LYPD4 LY6H	5.78e-03	20	107	2	PF00021
Pubmed	Markers of nonselective and specific NK cell activation.	IFNAR1 TYROBP LY6H	2.99e-08	3	109	3	23656738
Pubmed	A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.	KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	1.61e-07	16	109	4	15028290
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	CASP8AP2 SETX TRIOBP LAMA5 ZFYVE1 TECPR2 TET1 ZNF516 CAPRIN2 CACNA1G ZMYM4	9.11e-07	529	109	11	14621295
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	UIMC1 CASP8AP2 SETX DTL ZNF629 HUWE1 YEATS2 SALL1 ZNF516 TANC1 ZMYM4	2.53e-06	588	109	11	38580884
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SPIRE2 SETX DTL ZNF629 PARD3B FSIP2 C2CD3 FAM117A SYDE2 TET1 TANC1 PLCH1 GEN1	3.15e-06	861	109	13	36931259
Pubmed	Hair keratin associated proteins: characterization of a second high sulfur KAP gene domain on human chromosome 21.	KRTAP10-1 KRTAP10-5 KRTAP10-3	4.85e-06	11	109	3	14962103
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	CASP8AP2 RANBP2 HUWE1 YEATS2 SALL1 TET1 ZNF516 LRP1 ZMYM4	7.10e-06	418	109	9	34709266
Pubmed	Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides.	ITGB1 TLN1	9.73e-06	2	109	2	11279249
Pubmed	Tetraspanin 3 promotes NSCLC cell proliferation via regulation of β1 integrin intracellular recycling.	ITGB1 TSPAN3	9.73e-06	2	109	2	39333841
Pubmed	Striking differences of LDL receptor-related protein 1B expression in mouse and human.	LRP1B LRP1	9.73e-06	2	109	2	15963947
Pubmed	GATA-1, G208S macrothrombocytes are deficient in talin: immunofluorescence studies.	GATA1 TLN1	9.73e-06	2	109	2	19437340
Pubmed	Low density lipoprotein receptor-related protein-1 promotes beta1 integrin maturation and transport to the cell surface.	ITGB1 LRP1	9.73e-06	2	109	2	14699139
Pubmed	Ly49H engagement compensates for the absence of type I interferon signaling in stimulating NK cell proliferation during murine cytomegalovirus infection.	IFNAR1 TYROBP	9.73e-06	2	109	2	19828630
Pubmed	BCL6 controls Th9 cell development by repressing Il9 transcription.	BCL6 IL9	9.73e-06	2	109	2	24879792
Pubmed	Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer.	ITGB1 TLN1	9.73e-06	2	109	2	35285795
Pubmed	Talin1 phosphorylation activates β1 integrins: a novel mechanism to promote prostate cancer bone metastasis.	ITGB1 TLN1	9.73e-06	2	109	2	24793790
Pubmed	Low density lipoprotein receptor-related protein 1 mediated endocytosis of β1-integrin influences cell adhesion and cell migration.	ITGB1 LRP1	9.73e-06	2	109	2	26610862
Pubmed	ADAMTS-10 and -6 differentially regulate cell-cell junctions and focal adhesions.	ADAMTS10 ADAMTS6	9.73e-06	2	109	2	27779234
Pubmed	Identification of RNase 8 as a novel human antimicrobial protein.	RNASE8 RNASE7	9.73e-06	2	109	2	16940129
Pubmed	Characterization of a novel phosphatidylinositol 3-phosphate-binding protein containing two FYVE fingers in tandem that is targeted to the Golgi.	ZFYVE1 EEA1	9.73e-06	2	109	2	11256955
Pubmed	Bartonella henselae engages inside-out and outside-in signaling by integrin β1 and talin1 during invasome-mediated bacterial uptake.	ITGB1 TLN1	9.73e-06	2	109	2	22045736
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	UIMC1 RANBP2 SETX ITGB1 YEATS2 SALL1 SLC4A1AP TLN1 ZMYM4	1.15e-05	444	109	9	34795231
Pubmed	Sall3 is required for the terminal maturation of olfactory glomerular interneurons.	RELN ETV1 SALL1	1.63e-05	16	109	3	18260139
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	OBSCN NOTCH2NLA ETV1 TRIOBP PARD3B HUWE1 ITGB1 PCNX2 YEATS2 CFAP20DC TECPR2 LRP1 TANC1 ABLIM2 USP3 ZMYM4	1.64e-05	1489	109	16	28611215
Pubmed	Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development.	ADAMTS10 FBN2 ADAMTS6	2.36e-05	18	109	3	35503090
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	RANBP2 OBSCN ZNF407 BCL6 KMT2E ITGB1 TLN1 ABLIM2 ZMYM4	2.79e-05	497	109	9	23414517
Pubmed	Reelin, Disabled 1, and beta 1 integrins are required for the formation of the radial glial scaffold in the hippocampus.	RELN ITGB1	2.91e-05	3	109	2	12244214
Pubmed	Endothelial basement membrane laminin 511 is essential for shear stress response.	LAMA5 ITGB1	2.91e-05	3	109	2	27940654
Pubmed	Triggering of effector functions on a CD8+ T cell clone upon the aggregation of an activatory CD94/kp39 heterodimer.	TYROBP KLRC3	2.91e-05	3	109	2	10201920
Pubmed	Disruption of focal adhesions by integrin cytoplasmic domain-associated protein-1 alpha.	ITGB1 TLN1	2.91e-05	3	109	2	12473654
Pubmed	Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage.	ADAMTS10 FBN2	2.91e-05	3	109	2	30201140
Pubmed	Beta1 integrin and alpha-dystroglycan binding sites are localized to different laminin-G-domain-like (LG) modules within the laminin alpha5 chain G domain.	LAMA5 ITGB1	2.91e-05	3	109	2	12519075
Pubmed	IQCJ-SCHIP1, a novel fusion transcript encoding a calmodulin-binding IQ motif protein.	SCHIP1 IQCJ-SCHIP1	2.91e-05	3	109	2	17045569
Pubmed	Laminin isoforms and their integrin receptors in glioma cell migration and invasiveness: Evidence for a role of alpha5-laminin(s) and alpha3beta1 integrin.	LAMA5 ITGB1	2.91e-05	3	109	2	17888902
Pubmed	The structure of the talin/integrin complex at a lipid bilayer: an NMR and MD simulation study.	ITGB1 TLN1	2.91e-05	3	109	2	20947017
Pubmed	α1- and α5-containing laminins regulate the development of bile ducts via β1 integrin signals.	LAMA5 ITGB1	2.91e-05	3	109	2	22761447
Pubmed	Interaction of reelin with amyloid precursor protein promotes neurite outgrowth.	RELN ITGB1	2.91e-05	3	109	2	19515914
Pubmed	Mice deficient in stem cell antigen-1 (Sca1, Ly-6A/E) develop normal primary and memory CD4+ and CD8+ T-cell responses to virus infection.	IFNAR1 LY6H	2.91e-05	3	109	2	19384870
Pubmed	OSP/claudin-11 forms a complex with a novel member of the tetraspanin super family and beta1 integrin and regulates proliferation and migration of oligodendrocytes.	ITGB1 TSPAN3	2.91e-05	3	109	2	11309411
Pubmed	IFNAR1 signaling in NK cells promotes persistent virus infection.	BCL6 IFNAR1	2.91e-05	3	109	2	33771858
Pubmed	Phosphatidylinositol phosphate kinase type 1gamma and beta1-integrin cytoplasmic domain bind to the same region in the talin FERM domain.	ITGB1 TLN1	2.91e-05	3	109	2	12782621
Pubmed	Spatial coordination of kindlin-2 with talin head domain in interaction with integrin β cytoplasmic tails.	ITGB1 TLN1	2.91e-05	3	109	2	22648415
Pubmed	Determination of cleavage site of Reelin between its sixth and seventh repeat and contribution of meprin metalloproteases to the cleavage.	RELN MEP1B	2.91e-05	3	109	2	26491063
Pubmed	Talin depletion reveals independence of initial cell spreading from integrin activation and traction.	ITGB1 TLN1	2.91e-05	3	109	2	19160486
Pubmed	Human NKG2E is expressed and forms an intracytoplasmic complex with CD94 and DAP12.	TYROBP KLRC3	2.91e-05	3	109	2	24935923
Pubmed	Talin-Dependent Integrin Activation Regulates VE-Cadherin Localization and Endothelial Cell Barrier Function.	ITGB1 TLN1	2.91e-05	3	109	2	30707047
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	SETX DTL OBSCN MARCHF7 HUWE1 ZFYVE1 ITGB1 C2CD5 TET1 SERINC3 SUCO USP3 GEN1	3.59e-05	1084	109	13	11544199
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	LRP1B LRP1 EEA1	3.82e-05	21	109	3	21337463
Pubmed	TCF7L2 regulates postmitotic differentiation programmes and excitability patterns in the thalamus.	RELN ETV1 CACNA1G	4.42e-05	22	109	3	32675279
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	SETX ZNF629 YEATS2 ZNF516 ZMYM4	4.80e-05	125	109	5	32891193
Pubmed	ADAMTS9-Mediated Extracellular Matrix Dynamics Regulates Umbilical Cord Vascular Smooth Muscle Differentiation and Rotation.	ITGB1 FBN2 LY6H	5.07e-05	23	109	3	26027930
Pubmed	Human mast cells adhere to and migrate on epithelial and vascular basement membrane laminins LM-332 and LM-511 via alpha3beta1 integrin.	LAMA5 ITGB1	5.82e-05	4	109	2	19752234
Pubmed	Evolution and cell-type specificity of human-specific genes preferentially expressed in progenitors of fetal neocortex.	NOTCH2NLA NOTCH2NLC	5.82e-05	4	109	2	29561261
Pubmed	mDYRK3 kinase is expressed selectively in late erythroid progenitor cells and attenuates colony-forming unit-erythroid development.	GATA1 DYRK3	5.82e-05	4	109	2	11159515
Pubmed	Talin 1 and paxillin facilitate distinct steps in rapid VLA-4-mediated adhesion strengthening to vascular cell adhesion molecule 1.	ITGB1 TLN1	5.82e-05	4	109	2	17597073
Pubmed	Evolution of Human Brain Size-Associated NOTCH2NL Genes Proceeds toward Reduced Protein Levels.	NOTCH2NLA NOTCH2NLC	5.82e-05	4	109	2	32330268
Pubmed	Reelin, integrin and DAB1 interactions during embryonic cerebral cortical development.	RELN ITGB1	5.82e-05	4	109	2	15703255
Pubmed	Schwannomin-interacting Protein 1 Isoform IQCJ-SCHIP1 Is a Multipartner Ankyrin- and Spectrin-binding Protein Involved in the Organization of Nodes of Ranvier.	SCHIP1 IQCJ-SCHIP1	5.82e-05	4	109	2	27979964
Pubmed	Tyrosine phosphorylation of type Igamma phosphatidylinositol phosphate kinase by Src regulates an integrin-talin switch.	ITGB1 TLN1	5.82e-05	4	109	2	14691141
Pubmed	Cell adhesion strengthening: contributions of adhesive area, integrin binding, and focal adhesion assembly.	ITGB1 TLN1	5.82e-05	4	109	2	16000373
Pubmed	Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling.	ITGB1 LRP1	5.82e-05	4	109	2	18037995
Pubmed	Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis.	ITGB1 IFNAR1	5.82e-05	4	109	2	17603494
Pubmed	Melanoma cells produce multiple laminin isoforms and strongly migrate on α5 laminin(s) via several integrin receptors.	LAMA5 ITGB1	5.82e-05	4	109	2	21195710
Pubmed	Structural diversity in integrin/talin interactions.	ITGB1 TLN1	5.82e-05	4	109	2	21134644
Pubmed	Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.	IFNAR1 LY6H	5.82e-05	4	109	2	25707806
Pubmed	Expression pattern of integrin beta 1 subunit in Purkinje cells of rat and cerebellar mutant mice.	RELN ITGB1	5.82e-05	4	109	2	8915827
Pubmed	Kindlin-3 is essential for integrin activation and platelet aggregation.	ITGB1 TLN1	5.82e-05	4	109	2	18278053
Pubmed	Genetic link between renal birth defects and congenital heart disease.	TMEM67 LAMA5 ADAMTS6	9.27e-05	28	109	3	27002738
Pubmed	Coordinate integrin and c-Met signaling regulate Wnt gene expression during epithelial morphogenesis.	LAMA5 ITGB1	9.67e-05	5	109	2	19176588
Pubmed	Talin1 regulates integrin turnover to promote embryonic epithelial morphogenesis.	ITGB1 TLN1	9.67e-05	5	109	2	21670148
Pubmed	Schwannomin-interacting protein-1 isoform IQCJ-SCHIP-1 is a late component of nodes of Ranvier and axon initial segments.	SCHIP1 IQCJ-SCHIP1	9.67e-05	5	109	2	18550753
Pubmed	FAK, talin and PIPKIγ regulate endocytosed integrin activation to polarize focal adhesion assembly.	ITGB1 TLN1	9.67e-05	5	109	2	27043085
Pubmed	Regulation of melanoma cell migration and invasion by laminin-5 and alpha3beta1 integrin (VLA-3).	LAMA5 ITGB1	9.67e-05	5	109	2	11964076
Pubmed	Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin.	ITGB1 TLN1	9.67e-05	5	109	2	26821125
Pubmed	CK2-regulated schwannomin-interacting protein IQCJ-SCHIP-1 association with AnkG contributes to the maintenance of the axon initial segment.	SCHIP1 IQCJ-SCHIP1	9.67e-05	5	109	2	25950943
Pubmed	Human-Specific NOTCH2NL Genes Affect Notch Signaling and Cortical Neurogenesis.	NOTCH2NLA NOTCH2NLC	9.67e-05	5	109	2	29856954
Pubmed	Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation.	NOTCH2NLA NOTCH2NLC	9.67e-05	5	109	2	29856955
Pubmed	Clustering of alpha(5)beta(1) integrins determines adhesion strength whereas alpha(v)beta(3) and talin enable mechanotransduction.	ITGB1 TLN1	9.67e-05	5	109	2	19805288
Pubmed	Beta integrin tyrosine phosphorylation is a conserved mechanism for regulating talin-induced integrin activation.	ITGB1 TLN1	9.67e-05	5	109	2	19843520
Pubmed	Quantification of integrin receptor agonism by fluorescence lifetime imaging.	ITGB1 TLN1	9.67e-05	5	109	2	18216331
Pubmed	Regulation of the interaction between PIPKI gamma and talin by proline-directed protein kinases.	ITGB1 TLN1	9.67e-05	5	109	2	15738269
Pubmed	Talin is required for integrin-mediated platelet function in hemostasis and thrombosis.	ITGB1 TLN1	9.67e-05	5	109	2	18086863
Pubmed	Reprogramming of murine macrophages through TLR2 confers viral resistance via TRAF3-mediated, enhanced interferon production.	TRAF3 IFNAR1	9.67e-05	5	109	2	23853595
Pubmed	Patterns of neurogenesis and amplitude of Reelin expression are essential for making a mammalian-type cortex.	RELN ETV1	9.67e-05	5	109	2	18197264
Pubmed	Normal sorting but defective endocytosis of the low density lipoprotein receptor in mice with autosomal recessive hypercholesterolemia.	LRP1 EEA1	9.67e-05	5	109	2	12746448
Pubmed	Close homolog of L1 modulates area-specific neuronal positioning and dendrite orientation in the cerebral cortex.	RELN ITGB1	1.45e-04	6	109	2	15504324
Pubmed	Candidate gene isolation and comparative analysis of a commonly deleted segment of 7q22 implicated in myeloid malignancies.	RELN KMT2E	1.45e-04	6	109	2	11597142
Pubmed	The timing of cortical neurogenesis is encoded within lineages of individual progenitor cells.	RELN ETV1	1.45e-04	6	109	2	16680166
Pubmed	Absence of Dap12 and the αvβ3 integrin causes severe osteopetrosis.	ITGB1 TYROBP	1.45e-04	6	109	2	25547154
Pubmed	Reelin binds alpha3beta1 integrin and inhibits neuronal migration.	RELN ITGB1	1.45e-04	6	109	2	10939329
Pubmed	A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1.	TRAF3 BCL6	1.45e-04	6	109	2	27135603
Pubmed	DNA-methyltransferase1 (DNMT1) binding to CpG rich GABAergic and BDNF promoters is increased in the brain of schizophrenia and bipolar disorder patients.	RELN TET1	1.45e-04	6	109	2	25476119
Pubmed	Rapid leukocyte migration by integrin-independent flowing and squeezing.	ITGB1 TLN1	1.45e-04	6	109	2	18451854
Pubmed	Macrophage network dynamics depend on haptokinesis for optimal local surveillance.	ITGB1 TLN1	1.45e-04	6	109	2	35343899
Pubmed	Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity.	TYROBP LRP1	2.02e-04	7	109	2	34910922
Pubmed	A putative role for microRNA-205 in mammary epithelial cell progenitors.	ITGB1 LY6H	2.02e-04	7	109	2	20103531
Pubmed	SHARPIN is an endogenous inhibitor of β1-integrin activation.	ITGB1 TLN1	2.02e-04	7	109	2	21947080
Pubmed	Talin1 has unique expression versus talin 2 in the heart and modifies the hypertrophic response to pressure overload.	ITGB1 TLN1	2.02e-04	7	109	2	23266827
Pubmed	Talin regulates integrin β1-dependent and -independent cell functions in ureteric bud development.	ITGB1 TLN1	2.02e-04	7	109	2	28993400
Pubmed	Lymphoangiocrine signals promote cardiac growth and repair.	RELN ITGB1	2.02e-04	7	109	2	33299187
Interaction	SLC23A1 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	3.46e-09	26	104	6	int:SLC23A1
Interaction	TNP2 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3 SLC4A1AP	1.08e-08	31	104	6	int:TNP2
Interaction	BCL6B interactions	NOTCH2NLA BCL6 KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	1.61e-08	33	104	6	int:BCL6B
Interaction	ZNF124 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3 ZNF526	2.17e-08	59	104	7	int:ZNF124
Interaction	ALDH3B1 interactions	KRT31 NOTCH2NLA MARCHF7 TNFRSF10A KRTAP10-8 KRTAP10-5 KRTAP10-3 ZMYM4	1.09e-07	111	104	8	int:ALDH3B1
Interaction	POM121L8P interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5	2.15e-07	11	104	4	int:POM121L8P
Interaction	ZNF439 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	2.45e-07	27	104	5	int:ZNF439
Interaction	FAM74A4 interactions	KRT31 NOTCH2NLA KRTAP10-8 KRTAP10-5 KRTAP10-3	2.45e-07	27	104	5	int:FAM74A4
Interaction	ZNF559 interactions	KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	4.62e-07	13	104	4	int:ZNF559
Interaction	KRTAP4-11 interactions	GATA1 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3 FBXO34	4.86e-07	92	104	7	int:KRTAP4-11
Interaction	FOXB1 interactions	RANBP2 KRT31 NOTCH2NLA HUWE1 KRTAP10-8 KRTAP10-3 SALL1 LRP1	4.94e-07	135	104	8	int:FOXB1
Interaction	CHRD interactions	GATA1 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3 LY6H	5.63e-07	94	104	7	int:CHRD
Interaction	LCE3E interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	6.52e-07	60	104	6	int:LCE3E
Interaction	SLC6A20 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	8.21e-07	34	104	5	int:SLC6A20
Interaction	KRTAP9-2 interactions	KRT31 GATA1 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3 FBXO34	1.05e-06	149	104	8	int:KRTAP9-2
Interaction	ZNF32 interactions	NOTCH2NLA KRTAP10-8 KRTAP10-5 KRTAP10-3	1.16e-06	16	104	4	int:ZNF32
Interaction	LCE3C interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	1.26e-06	67	104	6	int:LCE3C
Interaction	ZNF578 interactions	KRTAP10-8 KRTAP10-5 KRTAP10-3 ZNF526	1.51e-06	17	104	4	int:ZNF578
Interaction	PCSK5 interactions	LYPD4 NOTCH2NLA KRTAP10-8 KRTAP10-3 ZNF547 LRP1 LY6H	1.85e-06	112	104	7	int:PCSK5
Interaction	ZNF264 interactions	KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3 ZNF526	2.15e-06	41	104	5	int:ZNF264
Interaction	TRPV6 interactions	NOTCH2NLA KRTAP10-8 KRTAP10-5 KRTAP10-3	2.44e-06	19	104	4	int:TRPV6
Interaction	KRTAP4-5 interactions	GATA1 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 FBXO34	2.66e-06	76	104	6	int:KRTAP4-5
Interaction	SMCP interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	3.35e-06	79	104	6	int:SMCP
Interaction	ZNF786 interactions	NOTCH2NLA KRTAP10-8 KRTAP10-3 SLC4A1AP	3.74e-06	21	104	4	int:ZNF786
Interaction	AVPI1 interactions	KRT31 KRTAP10-1 KRTAP10-8 KRTAP10-3 GAPDHS	4.77e-06	48	104	5	int:AVPI1
Interaction	LCE1B interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	5.13e-06	85	104	6	int:LCE1B
Interaction	CHRNG interactions	KRT31 NOTCH2NLA KRTAP10-8 KRTAP10-3	5.49e-06	23	104	4	int:CHRNG
Interaction	MOBP interactions	KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	5.49e-06	23	104	4	int:MOBP
Interaction	ZNF587 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3 ZNF547	6.41e-06	135	104	7	int:ZNF587
Interaction	SPATA3 interactions	KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	6.57e-06	24	104	4	int:SPATA3
Interaction	GLRX3 interactions	KRT31 GATA1 NOTCH2NLA BCL6 KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	6.66e-06	191	104	8	int:GLRX3
Interaction	KRTAP5-6 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	9.21e-06	94	104	6	int:KRTAP5-6
Interaction	FBXO34 interactions	ITGB1 KRTAP10-1 KRTAP10-8 KRTAP10-5 FBXO34	9.41e-06	55	104	5	int:FBXO34
Interaction	MXI1 interactions	KRT31 NOTCH2NLA KRTAP10-8 KRTAP10-5 KRTAP10-3	9.41e-06	55	104	5	int:MXI1
Interaction	SHFL interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	1.10e-05	97	104	6	int:SHFL
Interaction	THAP10 interactions	KRTAP10-8 KRTAP10-5 KRTAP10-3 RNASE7	1.44e-05	29	104	4	int:THAP10
Interaction	ZNF433 interactions	KRTAP10-1 KRTAP10-5 KRTAP10-3	1.56e-05	10	104	3	int:ZNF433
Interaction	CCDC26 interactions	NOTCH2NLA KRTAP10-8 KRTAP10-3	1.56e-05	10	104	3	int:CCDC26
Interaction	ZNF572 interactions	KRT31 KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	1.57e-05	61	104	5	int:ZNF572
Interaction	KRTAP12-1 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	1.84e-05	63	104	5	int:KRTAP12-1
Interaction	PGAP6 interactions	KRT31 NOTCH2NLA KRTAP10-8 KRTAP10-3	1.89e-05	31	104	4	int:PGAP6
Interaction	KRTAP10-5 interactions	GATA1 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3 FBXO34	1.94e-05	160	104	7	int:KRTAP10-5
Interaction	KRTAP10-11 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 FBXO34	1.99e-05	64	104	5	int:KRTAP10-11
Interaction	KRTAP4-12 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3 FBXO34	2.02e-05	161	104	7	int:KRTAP4-12
Interaction	NPDC1 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	2.15e-05	65	104	5	int:NPDC1
Interaction	DOCK2 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-3	2.31e-05	66	104	5	int:DOCK2
Interaction	KRTAP5-3 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 FBXO34	2.31e-05	66	104	5	int:KRTAP5-3
Interaction	SPRY1 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	2.39e-05	111	104	6	int:SPRY1
Interaction	ZNF101 interactions	KRTAP10-1 KRTAP10-8 KRTAP10-3 LY6H	2.44e-05	33	104	4	int:ZNF101
Interaction	KRTAP9-4 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5	2.44e-05	33	104	4	int:KRTAP9-4
Interaction	C17orf50 interactions	KRTAP10-1 KRTAP10-8 KRTAP10-5	2.84e-05	12	104	3	int:C17orf50
Interaction	GLIDR interactions	KRTAP10-8 KRTAP10-5 KRTAP10-3	2.84e-05	12	104	3	int:GLIDR
Interaction	LCE2A interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	2.87e-05	69	104	5	int:LCE2A
Interaction	KLK8 interactions	KRT31 NOTCH2NLA KRTAP10-8 KRTAP10-3	3.10e-05	35	104	4	int:KLK8
Interaction	NAXD interactions	KRT31 NOTCH2NLA BCL6 KRTAP10-8 KRTAP10-3	3.30e-05	71	104	5	int:NAXD
Interaction	WT1-AS interactions	NOTCH2NLA KRTAP10-8 KRTAP10-5	3.68e-05	13	104	3	int:WT1-AS
Interaction	LCE3D interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5	3.78e-05	73	104	5	int:LCE3D
Interaction	ZNF417 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3 ZNF547	3.85e-05	178	104	7	int:ZNF417
Interaction	MAPKBP1 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-3	4.03e-05	74	104	5	int:MAPKBP1
Interaction	PRR19 interactions	KRT31 NOTCH2NLA KRTAP10-8	4.66e-05	14	104	3	int:PRR19
Interaction	RTN4RL1 interactions	NOTCH2NLA KRTAP10-8 KRTAP10-3	4.66e-05	14	104	3	int:RTN4RL1
Interaction	CATSPER1 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	4.88e-05	126	104	6	int:CATSPER1
Interaction	ZNF440 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5	5.30e-05	40	104	4	int:ZNF440
Interaction	ADAMTSL3 interactions	NOTCH2NLA KRTAP10-8 KRTAP10-3	5.81e-05	15	104	3	int:ADAMTSL3
Interaction	C10orf62 interactions	TRAF3 KRTAP10-8 KRTAP10-3	5.81e-05	15	104	3	int:C10orf62
Interaction	ZNF625 interactions	KRTAP10-1 KRTAP10-8 KRTAP10-3	5.81e-05	15	104	3	int:ZNF625
Interaction	LCE4A interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5	5.87e-05	80	104	5	int:LCE4A
Interaction	KRTAP4-7 interactions	NOTCH2NLA KRTAP10-8 KRTAP10-3	7.12e-05	16	104	3	int:KRTAP4-7
Interaction	TYMSOS interactions	KRTAP10-8 KRTAP10-5 KRTAP10-3	7.12e-05	16	104	3	int:TYMSOS
Interaction	CCER1 interactions	KRT31 NOTCH2NLA KRTAP10-3	7.12e-05	16	104	3	int:CCER1
Interaction	PCED1A interactions	NOTCH2NLA KRTAP10-8 KRTAP10-3	7.12e-05	16	104	3	int:PCED1A
Interaction	SCNM1 interactions	KRT31 NOTCH2NLA KRTAP10-8 KRTAP10-5 KRTAP10-3 ZNF526 ZNF547	7.32e-05	197	104	7	int:SCNM1
Interaction	ZFYVE21 interactions	KRT31 NOTCH2NLA KRTAP10-8 KRTAP10-5 KRTAP10-3	7.42e-05	84	104	5	int:ZFYVE21
Interaction	BRME1 interactions	KRT31 NOTCH2NLA KRTAP10-8 KRTAP10-3	7.75e-05	44	104	4	int:BRME1
Interaction	ZNF20 interactions	KRT31 KRTAP10-8 KRTAP10-5 KRTAP10-3	7.75e-05	44	104	4	int:ZNF20
Interaction	LINC00656 interactions	NOTCH2NLA KRTAP10-8	7.89e-05	3	104	2	int:LINC00656
Interaction	CAMK1G interactions	CAMK1D KRTAP10-1 KRTAP10-8	8.61e-05	17	104	3	int:CAMK1G
Interaction	KRTAP9-3 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 FBXO34	8.76e-05	140	104	6	int:KRTAP9-3
Interaction	FARS2 interactions	KRT31 NOTCH2NLA KRTAP10-8 KRTAP10-5 KRTAP10-3 ZNF526	9.11e-05	141	104	6	int:FARS2
Interaction	HPCAL1 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	9.27e-05	88	104	5	int:HPCAL1
Interaction	ASPSCR1 interactions	KRT31 NOTCH2NLA HUWE1 KRTAP10-8 LRP1	9.78e-05	89	104	5	int:ASPSCR1
Interaction	AEN interactions	KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	1.01e-04	47	104	4	int:AEN
Interaction	ITGB5 interactions	KRT31 NOTCH2NLA BCL6 KRTAP10-8 TLN1 KLRC3	1.15e-04	147	104	6	int:ITGB5
Interaction	ZNF138 interactions	KRTAP10-1 KRTAP10-8 KRTAP10-3	1.22e-04	19	104	3	int:ZNF138
Interaction	TAPBPL interactions	KRT31 NOTCH2NLA KRTAP10-8	1.22e-04	19	104	3	int:TAPBPL
Interaction	KRTAP26-1 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	1.27e-04	94	104	5	int:KRTAP26-1
Interaction	KRTAP10-1 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3 FBXO34	1.43e-04	153	104	6	int:KRTAP10-1
Interaction	NPBWR2 interactions	KRT31 NOTCH2NLA KRTAP10-3	1.43e-04	20	104	3	int:NPBWR2
Interaction	OTX1 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	1.53e-04	155	104	6	int:OTX1
Interaction	TSPAN4 interactions	NOTCH2NLA ITGB1 KRTAP10-1 KRTAP10-8	1.61e-04	53	104	4	int:TSPAN4
Interaction	GFOD1 interactions	KRT31 NOTCH2NLA KRTAP10-8 KRTAP10-3	1.61e-04	53	104	4	int:GFOD1
Interaction	GARIN6 interactions	KRT31 NOTCH2NLA KRTAP10-8	1.66e-04	21	104	3	int:GARIN6
Interaction	KRTAP9-8 interactions	NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 FBXO34	1.70e-04	100	104	5	int:KRTAP9-8
Interaction	HHEX interactions	NOTCH2NLA KRTAP10-8 KRTAP10-5 KRTAP10-3	1.74e-04	54	104	4	int:HHEX
Interaction	PDE9A interactions	TRAF3 NOTCH2NLA KRTAP10-8 KRTAP10-3	1.74e-04	54	104	4	int:PDE9A
Interaction	SMOC1 interactions	NOTCH2NLA KRTAP10-8 KRTAP10-3 LRP1	1.74e-04	54	104	4	int:SMOC1
Interaction	CRH interactions	KRT31 NOTCH2NLA KRTAP10-8	1.91e-04	22	104	3	int:CRH
Interaction	JOSD1 interactions	KRT31 NOTCH2NLA KRTAP10-8 KRTAP10-3	2.00e-04	56	104	4	int:JOSD1
Interaction	GNE interactions	KRT31 NOTCH2NLA KRTAP10-8 KRTAP10-5 KRTAP10-3	2.04e-04	104	104	5	int:GNE
Interaction	CREB5 interactions	KRT31 NOTCH2NLA KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	2.08e-04	164	104	6	int:CREB5
Cytoband	21q22.3	KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	2.56e-04	128	109	4	21q22.3
Cytoband	2q24.2	MARCHF7 TANC1	1.25e-03	22	109	2	2q24.2
Cytoband	3q27	BCL6 FETUB	1.62e-03	25	109	2	3q27
Cytoband	Ensembl 112 genes in cytogenetic band chr21q22	KRTAP10-1 KRTAP10-8 KRTAP10-5 IFNAR1 KRTAP10-3	2.11e-03	377	109	5	chr21q22
Cytoband	18q23	ZNF407 ZNF516	2.17e-03	29	109	2	18q23
Cytoband	Ensembl 112 genes in cytogenetic band chr3q27	BCL6 FETUB YEATS2	3.58e-03	128	109	3	chr3q27
Cytoband	7q22	RELN MUC3A	3.71e-03	38	109	2	7q22
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	C2CD5 C2CD3 SYDE2	4.44e-04	36	75	3	823
GeneFamily	Keratin associated proteins	KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	1.09e-03	109	75	4	619
GeneFamily	Low density lipoprotein receptors	LRP1B LRP1	1.29e-03	13	75	2	634
GeneFamily	Ribonuclease A family	RNASE8 RNASE7	1.29e-03	13	75	2	723
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS10 ADAMTS6	2.77e-03	19	75	2	50
GeneFamily	CD molecules\|Mucins	MUC3A MUC6	3.39e-03	21	75	2	648
Coexpression	GAO_LARGE_INTESTINE_ADULT_CJ_IMMUNE_CELLS	OBSCN ETV1 LAMA5 HEG1 SALL1 SCUBE2 SYDE2 TET1 LRP1 TRIM49B FILIP1L	6.52e-06	505	106	11	M39167
Coexpression	GSE9650_EXHAUSTED_VS_MEMORY_CD8_TCELL_UP	GATA1 ETV1 TG TLN1 KHK GAPDHS EEA1	1.75e-05	200	106	7	M5838
ToppCell	Control-Epithelial_cells-ECM-high_epithelial\|Control / group, cell type (main and fine annotations)	LAMA5 PARD3B HEG1 IQCJ-SCHIP1 TANC1 RP1	3.91e-06	170	109	6	e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIRE2 SPATA2 HEG1 SALL1 OTOGL GEN1	4.18e-06	172	109	6	f2c17c49b375b28ad47dc6cabda62f1c238023dd
ToppCell	facs-Heart-LV-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPIRE2 SPATA2 HEG1 SALL1 OTOGL GEN1	4.18e-06	172	109	6	6ab4f01098dddb789df298ddf97b3c384405ee6c
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN OBSCN LRP1B FBN2 OTOGL PLCH1	6.16e-06	184	109	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN OBSCN LRP1B FBN2 OTOGL PLCH1	6.16e-06	184	109	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN OBSCN LRP1B FBN2 OTOGL PLCH1	6.16e-06	184	109	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	OBSCN LAMA5 FBN2 SALL1 SCUBE2 CACNA1G	6.96e-06	188	109	6	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ETV1 KMT2E ITGB1 HEG1 TLN1 FILIP1L	7.40e-06	190	109	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ETV1 LAMA5 ITGB1 SALL1 LY6H FILIP1L	9.09e-06	197	109	6	ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 FBN2 SALL1 LY6H KLRC3 FILIP1L	9.09e-06	197	109	6	2e3d64648a1e4f01b9256a96b94b8a640ee1824c
ToppCell	ICU-SEP-Lymphocyte-T_NK-Treg\|ICU-SEP / Disease, Lineage and Cell Type	OBSCN ETV1 PCNX2 FSIP2 TET1	2.89e-05	145	109	5	ee99b58462f955b96d036aa67e343db047d66f64
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	KRT31 KRTAP10-1 KRTAP10-8 KRTAP10-5 KRTAP10-3	2.99e-05	146	109	5	522c32103c24fc26836bb5b642083904682d9292
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PARD3B BCL6 CFAP20DC ADAMTS6 PLCH1	3.51e-05	151	109	5	090b067873740c282865e2d02cf47d5cb3dd7607
ToppCell	TCGA-Thryoid-Solid_Tissue_Normal-Thryoid_normal_tissue-Thryoid_normal_tissue-3\|TCGA-Thryoid / Sample_Type by Project: Shred V9	RELN LRP1B ZNF804B PLCH1 ADGRA3	3.86e-05	154	109	5	4e9203c220a44c70cd7979796a0b461991422257
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZNF629 NRG2 TET1 CD48 DYRK3	5.36e-05	165	109	5	475905d608fac628960188ae4a18010b8097417e
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	TMEM67 PARD3B ADAMTS10 LY6H ABLIM2	5.84e-05	168	109	5	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	droplet-Lung-nan-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL6 ITGB1 TYROBP TLN1 FILIP1L	6.01e-05	169	109	5	ba023ee7bb165c2bfbefc2d969ff32ca1eeed33b
ToppCell	droplet-Lung-nan-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL6 ITGB1 TYROBP TLN1 FILIP1L	6.01e-05	169	109	5	c96e0f3241d13926dbee9f91c0c8c5bfa7479a0d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NOTCH2NLA OTOGL SYDE2 IQCJ-SCHIP1 PLCH1	6.89e-05	174	109	5	ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAMK1D BCL6 C2CD3 FAM117A TET1	7.08e-05	175	109	5	bb058e714d21a0ec8532eaf3c7dd2faf78016bc0
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	NOTCH2NLA OTOGL SYDE2 IQCJ-SCHIP1 PLCH1	7.28e-05	176	109	5	40993c41c1017b53039a337174fc56632b278609
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	ETV1 ADAMTS10 HEG1 LRP1 FILIP1L	7.68e-05	178	109	5	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ADAMTS6 OTOGL ZNF804B IQCJ-SCHIP1 PLCH1	7.88e-05	179	109	5	8766a5a066091879f521acfc612abf563ff78808
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM67 OBSCN FBN2 LY6H DYRK3	7.88e-05	179	109	5	a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SPIRE2 GATA1 RP1 PLXNB3	8.09e-05	180	109	5	d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SPIRE2 GATA1 RP1 PLXNB3	8.09e-05	180	109	5	dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DTL TG ADAMTS6 ABLIM2 GEN1	8.52e-05	182	109	5	3948422707d6d5e021bcd7158e2eb69143613f62
ToppCell	droplet-Marrow-nan-3m-Hematologic-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 SETX ITGB1 TET1 SUCO	8.52e-05	182	109	5	e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DTL TG ADAMTS6 ABLIM2 GEN1	8.52e-05	182	109	5	fe46819c153a81911864473badc794f243705f98
ToppCell	droplet-Marrow-nan-3m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 SETX ITGB1 TET1 SUCO	8.52e-05	182	109	5	1710eab3037a87609d21838be2d2d29c3bc36651
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGB1 FBN2 SALL1 ADAMTS6 FILIP1L	8.75e-05	183	109	5	af8d86f15a549064530d94bd47081daf59d58ecd
ToppCell	droplet-Heart-HEART-1m-Neuronal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN SPIRE2 TG CAPRIN2 PLXNB3	9.44e-05	186	109	5	fddc6b93f98b10aaf8d4ebc142b46d8213f3129d
ToppCell	droplet-Marrow-nan-3m-Hematologic-erythroblast\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 DTL GATA1 FAM117A GEN1	1.02e-04	189	109	5	8a38baee58a27c2fa3f4bd131ab9f15723ed9295
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN OBSCN HEG1 FBN2 LY6H	1.04e-04	190	109	5	3b8d1e66ae68c1eee64095e75195d76d97e24026
ToppCell	facs-GAT-Fat-3m\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HUWE1 BCL6 ITGB1 TYROBP SERINC3	1.04e-04	190	109	5	1d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	CAMK1D NRG2 LRP1B ADAMTS6 FILIP1L	1.04e-04	190	109	5	938d1f66094b1c94606e0d40213a39e5112f3322
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN OBSCN HEG1 FBN2 LY6H	1.04e-04	190	109	5	dc655e4782aab274f0c9b6e36a5ce315e3a1a4b9
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN HEG1 FBN2 TANC1 PLCH1	1.12e-04	193	109	5	c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN HEG1 FBN2 TANC1 PLCH1	1.12e-04	193	109	5	2189da4b727e25e62669d7b9257f06493be21a27
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RELN HEG1 FBN2 TANC1 PLCH1	1.15e-04	194	109	5	83863da11dfbe59b2d0a2c08db40b537c150588c
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	CAMK1D OBSCN OTOGL IQCJ-SCHIP1 TANC1	1.15e-04	194	109	5	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ETV1 ITGB1 ADAMTS10 FBN2 FILIP1L	1.18e-04	195	109	5	2514c1f23424b5fc664d326d31ffd22bafe74ef8
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ETV1 ITGB1 ADAMTS10 FBN2 FILIP1L	1.21e-04	196	109	5	e4d04e1f82779e8afd4e32bbe38d1d3f6f64ab50
ToppCell	PND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ETV1 ITGB1 ADAMTS10 FBN2 FILIP1L	1.21e-04	196	109	5	f0fd7db22985d2bc84dc8bcbdb2d552e280121dd
ToppCell	PND10-Mesenchymal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ETV1 ITGB1 TSPAN3 LRP1 FILIP1L	1.21e-04	196	109	5	ace167a40adb7022b365be3c2b1cbd4ba963739a
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 FBN2 SALL1 LY6H FILIP1L	1.24e-04	197	109	5	1da8ba5bbab232add6e43ad78b15c2339d0c2bc3
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_alveolar-AT1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMA5 YEATS2 HEG1 IQCJ-SCHIP1 RP1	1.24e-04	197	109	5	8d5097898dd01cedb04cb694cb480c931e08462c
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ETV1 ITGB1 ADAMTS10 FBN2 FILIP1L	1.24e-04	197	109	5	26475b9e4d6bfc0ae818dea13d139888ed7e92f1
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ETV1 TSPAN3 FBN2 ADAMTS6 CACNA1G	1.24e-04	197	109	5	3fe665c0277d091290b63f0dd24c0c6536a45309
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGB1 SALL1 SCUBE2 LY6H FILIP1L	1.24e-04	197	109	5	69fde2d27881f8408216e231c71cfdbd96f28d45
ToppCell	PND14-Mesenchymal\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ETV1 TSPAN3 ADAMTS10 LRP1 FILIP1L	1.24e-04	197	109	5	9a14bc2e7d6081e2ab0e2e5555fc8804f13d3dbe
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ETV1 ITGB1 ADAMTS10 FBN2 FILIP1L	1.24e-04	197	109	5	155e63b33302a87393ace699b2f6d73abe9c5763
ToppCell	PND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-SCMF-SCMF_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ETV1 ITGB1 ADAMTS10 FBN2 FILIP1L	1.27e-04	198	109	5	a4005a49cf6709b543994ceb51ecd5dc46197fa9
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NOTCH2NLA LAMA5 BCL6 LRP1 PLXNB3	1.27e-04	198	109	5	399760b6b6fef8639ded53b14f251b9fce600e81
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSPAN3 FBN2 SCUBE2 LRP1 CACNA1G	1.27e-04	198	109	5	524305c5d7b1d53e86ec0af775efefa3e0955e47
ToppCell	normal_Lung-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	LAMA5 ITGB1 ADAMTS6 TLN1 FILIP1L	1.30e-04	199	109	5	d65847ceb68a560798df3f73e6f838e7c3e38a1c
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 ITGB1 SCUBE2 LY6H FILIP1L	1.30e-04	199	109	5	ec74ff85d6b61013b1f785b2fca343759feb7843
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 FBN2 SALL1 LRP1 KLRC3	1.30e-04	199	109	5	edba1833ef5c4ca122d7c32f97670314e005f93b
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NOTCH2NLA LAMA5 BCL6 LRP1 PLXNB3	1.30e-04	199	109	5	85bb28369e0568b7b3bda095722102fc793f60ef
ToppCell	5'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FBN2 SCUBE2 LRP1 LY6H FILIP1L	1.30e-04	199	109	5	e78f661b40da34768469549b6e755d330be6bbd8
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN HEG1 FBN2 TANC1 PLCH1	1.33e-04	200	109	5	a9cdddc4e985dae59521e557479c24fcc2ac727d
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6--L3-5\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN HEG1 FBN2 TANC1 PLCH1	1.33e-04	200	109	5	33b9199e0dfc267e2cea20b82d1c167f8adcc635
ToppCell	Tracheal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ETV1 ADAMTS10 OTOGL ABLIM2 FILIP1L	1.33e-04	200	109	5	8158f4eaeff945a6788c8e732b7a1b0d78052a06
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	SCHIP1 OBSCN ADAMTS10 SYDE2 DYRK3	1.33e-04	200	109	5	6b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN HEG1 FBN2 TANC1 PLCH1	1.33e-04	200	109	5	347a510755374c6a66acee326565dfc447993f18
ToppCell	Tracheal-10x3prime_v2-Stromal-Pericyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ETV1 ADAMTS10 OTOGL ABLIM2 FILIP1L	1.33e-04	200	109	5	600d56257b1b0cda8ed2fd0db92c6551711f7d6d
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	SETX HEG1 SERINC3 TANC1 LY6H	1.33e-04	200	109	5	432384faeade8e609154fab3d96c955a8ec868dd
ToppCell	Neuronal-Inhibitory-iB-iB_4(SST)-ADGRG6\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RELN HEG1 FBN2 TANC1 PLCH1	1.33e-04	200	109	5	9719fabddc34051949468a7520289e3c750de4f8
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	RELN TRAF3 PARD3B HOXA13 TET1 LRP1 FILIP1L	2.95e-04	364	103	7	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	urate measurement, bone density	CASP8AP2 ETV1 LAMA5 MARCHF7 TG GRAMD1B FSIP2 SALL1 ZNF516	3.24e-04	619	103	9	EFO_0003923, EFO_0004531
Disease	alpha fetoprotein measurement	SETX SHLD1 TET1 GEN1	4.25e-04	100	103	4	EFO_0010583
Disease	corpus callosum volume measurement	SCHIP1 TG TLN1 IQCJ-SCHIP1	4.25e-04	100	103	4	EFO_0010299
Disease	cystic kidney disease (implicated_via_orthology)	TMEM67 LAMA5	5.33e-04	10	103	2	DOID:2975 (implicated_via_orthology)
Disease	developmental disorder of mental health (implicated_via_orthology)	PARD3B TANC1 PLXNB3	6.77e-04	49	103	3	DOID:0060037 (implicated_via_orthology)
Disease	Polydactyly	TMEM67 HOXA13 C2CD3 SALL1	7.67e-04	117	103	4	C0152427
Disease	brain disease (is_implicated_in)	RANBP2 TRAF3	7.78e-04	12	103	2	DOID:936 (is_implicated_in)
Disease	3-hydroxyanthranilic acid measurement	TG PCNX2	1.23e-03	15	103	2	EFO_0010447
Disease	body fat percentage	RELN TRAF3 PARD3B HOXA13 TET1 LRP1 FILIP1L	1.64e-03	488	103	7	EFO_0007800
Disease	hydrocephalus (implicated_via_orthology)	TMEM67 ITGB1	1.99e-03	19	103	2	DOID:10908 (implicated_via_orthology)
Disease	intraocular pressure measurement	RELN ETV1 TRIOBP PARD3B FBN2 ADAMTS6 ZNF516	2.08e-03	509	103	7	EFO_0004695
Disease	migraine disorder, endometriosis	CAMK1D ETV1 LRP1B	2.15e-03	73	103	3	EFO_0001065, MONDO_0005277
Disease	Neutropenia	GATA1 TNFRSF10A	2.43e-03	21	103	2	C0027947
Disease	temperament and character inventory	TG FBN2	3.17e-03	24	103	2	EFO_0004825
Disease	longevity	SPIRE2 ETV1 SYDE2 ZNF516 RP1	3.24e-03	284	103	5	EFO_0004300

Protein segments in the cluster

Peptide	Gene	Start	Entry
KNQSVPLSCCRETAS	TSPAN3	166	O60637
SAAQKRACNTATCVT	CALCB	76	P10092
APKCPNSSAESSCTN	ADGRA3	1086	Q8IWK6
AFTCCTNDKATQTPL	FAM117A	111	Q9C073
LLASCSKNCTNSPAI	FBXO34	221	Q9NWN3
KSPSTAILCNTCGNV	ABLIM2	16	Q6H8Q1
AKCNPSNSSPSSAAC	DTL	436	Q9NZJ0
SDSASKSCVPSRNCL	CASP8AP2	41	Q9UKL3
LSCTASNSNRSTPAC	GRAMD1B	6	Q3KR37
VSQVCESPQCSSSSA	ATP10D	676	Q9P241
CLSKSNRCITNSIPA	ADAMTS10	501	Q9H324
QQCESKCDSTPISNT	ADAMTS6	1066	Q9UKP5
ACQCPSKQNQTTAIS	RANBP2	1746	P49792
SSSLKCVACDASKPT	RANBP2	1796	P49792
NGSTCTTVANQFSCK	NOTCH2NLA	116	Q7Z3S9
FSQLICTCNSLKTSP	INTS7	631	Q9NVH2
AKLRNPCTSEQNCTS	ITGB1	201	P05556
LASCQAPKTFKSCSQ	MUC6	761	Q6W4X9
SKPCFENCQNAVTTS	PARD3B	606	Q8TEW8
NPKCKSAEQSCNSSF	LRP1B	2881	Q9NZR2
LSNPTSKAECSAEQC	ME1	406	P48163
NLPSNPCATTNACSK	KRT31	366	Q15323
CSIDPKLTSCATNAS	LRP1	3776	Q07954
IKESPCTKSQASSCS	FETUB	211	Q9UGM5
SKCCQTTASANIEST	FSIP2	6716	Q5CZC0
LSGCQNITSTKCNFS	IFNAR1	76	P17181
SKSPQDSLSSSCPQC	PCNX2	301	A6NKB5
DSLSSSCPQCDTIVA	PCNX2	306	A6NKB5
LLQCSTVCSVNSSSL	PLXNB3	1091	Q9ULL4
NSCQDSQTLCFKPDS	MUC3A	3121	Q02505
CKRNDTSNSSCPLQS	CSTL1	91	Q9H114
CSEISSACSQEQPFK	ETV1	96	P50549
SVGTSKCNSPACVEA	NRG2	541	O14511
NECPSPDTSQNTCKS	KMT2E	1336	Q8IZD2
NFVTTNSCPLAASTC	LYPD4	156	Q6UWN0
SSSASVNSCAVNPCL	HEG1	981	Q9ULI3
KPATANSANECQSCN	LAMA5	346	O15230
ERGNKACSPCSSQSS	HUWE1	3366	Q7Z6Z7
PASKCHCSANVTSCL	IL9	41	P15248
NGSTCTTVANQFSCK	NOTCH2NLC	116	P0DPK4
CTLTTNSSHCTPKQC	LY6H	31	O94772
NSSHCTPKQCQPSDT	LY6H	36	O94772
QTQCLPSSSNSIGCS	RELN	3156	P78509
DCQTSTQFCVSAPRK	OBSCN	496	Q5VST9
IPSASSCQKAFSTCG	OR6V1	226	Q8N148
SKRAGTQCTNCQTTT	GATA1	251	P15976
FCAECSAKNALTPSS	EEA1	1381	Q15075
SCHQKSPASTQVPCS	C2CD3	1601	Q4AC94
SPSQSLVACECEASK	C2CD3	2146	Q4AC94
LETQSTGACQSSCKI	CACNA1G	636	O43497
EGSVLSFKCSQSTPC	FILIP1L	841	Q4L180
KSDCQPNSPTESCSS	BCL6	336	P41182
PNSPTESCSSKNACI	BCL6	341	P41182
ESCSSKNACILQASG	BCL6	346	P41182
QATSSPVTCSSNACL	CAPRIN2	681	Q6IMN6
SSSNLLIEPCKCTGS	MARCHF7	561	Q9H992
CFPDSTKSSLSSLQC	GEN1	866	Q17RS7
KGDTPSSCCIINNSN	KHK	91	P50053
LPTCSKDSSSCCQQS	KRTAP10-1	111	P60331
KDSSSCCQQSSCQPT	KRTAP10-1	116	P60331
GASSSCCQQSSRQPA	KRTAP10-3	131	P60369
PTCSKDSSSCCQQSS	KRTAP10-5	101	P60370
SGASSLCCQKSSCQP	KRTAP10-8	181	P60410
QISSTCGSKSIQQCS	FBN2	136	P35556
NASCTTNCLAPLAKV	GAPDHS	221	O14556
CQVSNSVSSKNGTVC	CD48	196	P09326
FSSVAATCQTPKIAC	RNASE7	76	Q9H1E1
KNNCVSCPGNTTTDF	SCUBE2	781	Q9NQ36
CNTCGKTFSSSSALQ	SALL1	1136	Q9NSC2
APSVQDLCSKTTCKN	MEP1B	601	Q16820
SSQQPTTNCQSSCTE	C2CD5	981	Q86YS7
CSPTVSQGKSSDCLN	DYRK3	111	O43781
LCETSIPTCTNSQKL	OTOGL	1941	Q3ZCN5
NCSTVNIQSVPKCSE	RP1	1211	P56715
TFVNTSRSCACSEPN	TMEM67	176	Q5HYA8
CDTQPVLKLSCSDTS	OR1L6	216	Q8NGR2
VVCNATNSSLSKNCA	SYDE2	341	Q5VT97
QSNSTKVTPCSECKS	SCHIP1	46	P0DPB3
PCNTFVDLTSACKIS	SETX	601	Q7Z333
PGSANSLSASVCKCL	SHLD1	111	Q8IYI0
PCSTLNSCVSKTAAN	TANC1	191	Q9C0D5
NSCVSKTAANKSPCE	TANC1	196	Q9C0D5
SLQACASKNSSSLLC	KLRC3	141	Q07444
SQSNSTKVTPCSECK	IQCJ-SCHIP1	121	B3KU38
KQCSPCSAAAQSSSG	HOXA13	151	P31271
LASQKDCLAPSTLCS	CAMK1D	341	Q8IU85
RDNPGTSSSQCCTQK	TRIOBP	861	Q9H2D6
TSSSQCCTQKENLRP	TRIOBP	866	Q9H2D6
CPSLEKQSSCNTVVF	TET1	956	Q8NFU7
SKNNRSCQPSTVEKC	CFAP20DC	166	Q6ZVT6
ATANPGKCLSCTNST	TRAK2	656	O60296
LDACASPTKSASACN	ZNF516	111	Q92618
PGATNTCTQCSKVSC	SPATA2	466	Q9UM82
LSSSSPKCTACQESI	TRAF3	81	Q13114
QAQAQSDCSCSTVSP	TYROBP	26	O43914
ISCLLKNCSSGPSET	ZNF804B	896	A4D1E1
SSVAITCQTPNIACK	RNASE8	76	Q8TDE3
ATQCALSTSQLVACT	TLN1	706	Q9Y490
LNACSGDAKSTSCIN	SPIRE2	376	Q8WWL2
LCQSSKDLCSVSAQS	TECPR2	1141	O15040
ISACTSLCNGQSQKT	SUCO	1181	Q9UBS9
CSCCPNSKNSTVTRL	SERINC3	26	Q13530
TTTRNTACQCKPGTF	TNFRSF10A	181	O00220
TSNCQENPCPSKSLS	PLCH1	1071	Q4KWH8
RPNSQILSCNKCATS	ZFYVE1	596	Q9HBF4
SASNKCCINGASTVV	USP3	296	Q9Y6I4
LSTQNTQPCETCSSL	ZNF547	81	Q8IVP9
CAAPIAVSQLSCSSS	WDR93	411	Q6P2C0
TNDISDQSKCPTLCT	ZNF502	136	Q8TBZ5
QLPCPQCSKSFASAS	ZNF526	441	Q8TF50
SPFLVQCSECTKSTG	TRIM49B	46	A6NDI0
LTVKPASGSQTLCAC	ZNF407	516	Q9C0G0
RPNTCSECGKSFTQS	ZNF629	176	Q9UEG4
SSAQCPSLCNVLKSG	TG	1141	P01266
TFSSSNQVSCPLCDQ	UIMC1	496	Q96RL1
TSAGVQVQCNSCKTS	ZMYM4	571	Q5VZL5
CVSQATVGTCKAATP	YEATS2	996	Q9ULM3
QDCSKTTSLCAGPSA	SLC4A1AP	721	Q9BWU0