Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvirus receptor activity

NPC1 EGFR SERPINB3 SERPINB4 CCR5

2.78e-0585835GO:0001618
GeneOntologyMolecularFunctionactin binding

MYO1A MAP1A IQGAP2 EGFR TRPM7 SYNE1 SVIL CCR5 ACTR3B UTRN

2.92e-054798310GO:0003779
GeneOntologyMolecularFunctionexogenous protein binding

NPC1 EGFR SERPINB3 SERPINB4 CCR5

2.94e-0586835GO:0140272
GeneOntologyMolecularFunctionactin filament binding

MYO1A IQGAP2 EGFR SYNE1 SVIL ACTR3B

3.68e-04227836GO:0051015
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

DNAH2 ODAD2 CFAP57 DNAH8

2.10e-0541824GO:0070286
MousePhenoabnormal submandibular gland branching morphogenesis

EGFR MMP14

5.42e-053602MP:0013542
MousePhenoabnormal respiratory epithelium morphology

NPC1 EGFR SERPINB3 SERPINB4 ODAD2 MMP14 LYST

6.28e-05235607MP:0010942
MousePhenoabnormal cellular cholesterol metabolism

NPC1 ABCA1 HP

6.94e-0519603MP:0003191
MousePhenoabnormal hypersensitivity reaction

PTGES2 TRPM7 SERPINB3 SERPINB4 CD207 CCR5

9.79e-05174606MP:0002148
DomainCH

IQGAP2 SYNE1 SPECC1 UTRN

2.00e-0465834SM00033
DomainCH

IQGAP2 SYNE1 SPECC1 UTRN

2.66e-0470834PF00307
Domain-

IQGAP2 SYNE1 SPECC1 UTRN

2.81e-04718341.10.418.10
DomainRIH_assoc

RYR2 ITPR2

2.89e-046832PF08454
DomainRIH_assoc-dom

RYR2 ITPR2

2.89e-046832IPR013662
DomainRIH_dom

RYR2 ITPR2

2.89e-046832IPR000699
DomainIns145_P3_rcpt

RYR2 ITPR2

2.89e-046832IPR014821
DomainRyanodine_recept-rel

RYR2 ITPR2

2.89e-046832IPR015925
DomainPH_BEACH

NBEAL2 LYST

2.89e-046832PF14844
Domain-

RYR2 ITPR2

2.89e-0468321.25.10.30
DomainRYDR_ITPR

RYR2 ITPR2

2.89e-046832PF01365
DomainIns145_P3_rec

RYR2 ITPR2

2.89e-046832PF08709
DomainCH

IQGAP2 SYNE1 SPECC1 UTRN

3.13e-0473834PS50021
DomainCH-domain

IQGAP2 SYNE1 SPECC1 UTRN

3.47e-0475834IPR001715
DomainSerpin_CS

SERPINB8 SERPINB3 SERPINB4

3.82e-0432833IPR023795
DomainPH-BEACH_dom

NBEAL2 LYST

5.37e-048832IPR023362
Domain-

NBEAL2 LYST

5.37e-0488322.30.29.40
DomainDHC_N1

DNAH2 DNAH8

5.37e-048832PF08385
DomainPH_BEACH

NBEAL2 LYST

5.37e-048832PS51783
DomainDynein_heavy_dom-1

DNAH2 DNAH8

5.37e-048832IPR013594
DomainSerpin_dom

SERPINB8 SERPINB3 SERPINB4

5.44e-0436833IPR023796
DomainSERPIN

SERPINB8 SERPINB3 SERPINB4

5.90e-0437833SM00093
DomainSERPIN

SERPINB8 SERPINB3 SERPINB4

5.90e-0437833PS00284
DomainSerpin

SERPINB8 SERPINB3 SERPINB4

6.38e-0438833PF00079
DomainBEACH_dom

NBEAL2 LYST

6.88e-049832IPR000409
DomainA1pp

GDAP2 PARP14

6.88e-049832SM00506
DomainMacro

GDAP2 PARP14

6.88e-049832PF01661
DomainBEACH

NBEAL2 LYST

6.88e-049832PS50197
DomainBeach

NBEAL2 LYST

6.88e-049832PF02138
Domain-

NBEAL2 LYST

6.88e-0498321.10.1540.10
DomainBeach

NBEAL2 LYST

6.88e-049832SM01026
DomainSerpin_fam

SERPINB8 SERPINB3 SERPINB4

6.89e-0439833IPR000215
DomainMIR

RYR2 ITPR2

8.58e-0410832PS50919
DomainMIR

RYR2 ITPR2

8.58e-0410832PF02815
DomainMIR

RYR2 ITPR2

8.58e-0410832SM00472
DomainMIR_motif

RYR2 ITPR2

8.58e-0410832IPR016093
DomainMACRO

GDAP2 PARP14

8.58e-0410832PS51154
DomainChromo_dom_subgr

CDY2A CDY1

8.58e-0410832IPR017984
DomainMacro_dom

GDAP2 PARP14

8.58e-0410832IPR002589
DomainSushi

CFHR2 HP CFHR5

1.60e-0352833PF00084
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH8

1.72e-0314832IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH8

1.72e-0314832IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH8

1.72e-0314832IPR013602
DomainDHC_N2

DNAH2 DNAH8

1.72e-0314832PF08393
DomainMT

DNAH2 DNAH8

1.72e-0314832PF12777
DomainAAA_8

DNAH2 DNAH8

1.72e-0314832PF12780
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH8

1.72e-0314832IPR011704
DomainAAA_5

DNAH2 DNAH8

1.72e-0314832PF07728
DomainCCP

CFHR2 HP CFHR5

1.78e-0354833SM00032
DomainDHC_fam

DNAH2 DNAH8

1.97e-0315832IPR026983
DomainDynein_heavy_dom

DNAH2 DNAH8

1.97e-0315832IPR004273
DomainDynein_heavy

DNAH2 DNAH8

1.97e-0315832PF03028
DomainSUSHI

CFHR2 HP CFHR5

1.98e-0356833PS50923
DomainSushi_SCR_CCP_dom

CFHR2 HP CFHR5

2.08e-0357833IPR000436
DomainCrotonase_core_superfam

CDY2A CDY1

2.54e-0317832IPR001753
DomainECH_1

CDY2A CDY1

2.54e-0317832PF00378
DomainPept_M10A_stromelysin-type

MMP21 MMP14

2.85e-0318832IPR016293
DomainPG_binding_1

MMP21 MMP14

3.52e-0320832PF01471
DomainPeptidoglycan-bd-like

MMP21 MMP14

3.52e-0320832IPR002477
DomainARM-type_fold

NBEAL2 BTAF1 ODAD2 LYST EIF3M ITPR2

4.00e-03339836IPR016024
DomainActinin_actin-bd_CS

SYNE1 UTRN

4.65e-0323832IPR001589
DomainHemopexin-like_dom

MMP21 MMP14

4.65e-0323832IPR000585
DomainHemopexin-like_repeat

MMP21 MMP14

4.65e-0323832IPR018487
DomainSpectrin

SYNE1 UTRN

4.65e-0323832PF00435
DomainM10A_MMP

MMP21 MMP14

4.65e-0323832IPR033739
DomainHemopexin

MMP21 MMP14

4.65e-0323832PF00045
Pubmed

Comparative genomic analysis of the clade B serpin cluster at human chromosome 18q21: amplification within the mouse squamous cell carcinoma antigen gene locus.

SERPINB8 SERPINB3 SERPINB4

2.37e-061186315203215
Pubmed

Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse.

SERPINB8 SERPINB3 SERPINB4

4.10e-061386311863365
Pubmed

The amplified mouse squamous cell carcinoma antigen gene locus contains a serpin (Serpinb3b) that inhibits both papain-like cysteine and trypsin-like serine proteinases.

SERPINB3 SERPINB4

6.04e-06286215203214
Pubmed

Increased Th1 immune response in SERPINB3 transgenic mice during acute liver failure.

SERPINB3 SERPINB4

6.04e-06286223354406
Pubmed

Common haplotypes at the CFH locus and low-frequency variants in CFHR2 and CFHR5 associate with systemic FHR concentrations and age-related macular degeneration.

CFHR2 CFHR5

6.04e-06286234260947
Pubmed

Characterization of novel squamous cell carcinoma antigen-related molecules in mice.

SERPINB3 SERPINB4

6.04e-06286215504361
Pubmed

SCCA2-like serpins mediate genetic predisposition to skin tumors.

SERPINB3 SERPINB4

6.04e-06286212702576
Pubmed

Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins.

SERPINB3 SERPINB4

6.04e-06286235022507
Pubmed

Mitochondrial calcium overload is a key determinant in heart failure.

RYR2 ITPR2

6.04e-06286226217001
Pubmed

Visualization of polarized membrane type 1 matrix metalloproteinase activity in live cells by fluorescence resonance energy transfer imaging.

EGFR MMP14

6.04e-06286218441011
Pubmed

SERPINB3/B4 contributes to early inflammation and barrier dysfunction in an experimental murine model of atopic dermatitis.

SERPINB3 SERPINB4

6.04e-06286225111616
Pubmed

Squamous cell carcinoma antigen production in nasal inverted papilloma.

SERPINB3 SERPINB4

6.04e-06286223168150
Pubmed

Overexpression of squamous cell carcinoma antigen variants in hepatocellular carcinoma.

SERPINB3 SERPINB4

6.04e-06286214970861
Pubmed

Co-expression of the squamous cell carcinoma antigens 1 and 2 in normal adult human tissues and squamous cell carcinomas.

SERPINB3 SERPINB4

6.04e-06286210653592
Pubmed

Serum squamous cell carcinoma antigen as an early indicator of response during therapy of cervical cancer.

SERPINB3 SERPINB4

6.04e-06286229112685
Pubmed

Circulating serpin tumor markers SCCA1 and SCCA2 are not actively secreted but reside in the cytosol of squamous carcinoma cells.

SERPINB3 SERPINB4

6.04e-06286210956412
Pubmed

SerpinB3 as a Pro-Inflammatory Mediator in the Progression of Experimental Non-Alcoholic Fatty Liver Disease.

SERPINB3 SERPINB4

6.04e-06286235874657
Pubmed

Serpin B4 isoform overexpression is associated with aberrant epithelial proliferation and lung cancer in idiopathic pulmonary fibrosis.

SERPINB3 SERPINB4

6.04e-06286222406480
Pubmed

Recurrent SERPINB3 and SERPINB4 mutations in patients who respond to anti-CTLA4 immunotherapy.

SERPINB3 SERPINB4

6.04e-06286227668655
Pubmed

Functional local crosstalk of inositol 1,4,5-trisphosphate receptor- and ryanodine receptor-dependent Ca2+ release in atrial cardiomyocytes.

RYR2 ITPR2

6.04e-06286228158491
Pubmed

Complement factor H-related hybrid protein deregulates complement in dense deposit disease.

CFHR2 CFHR5

6.04e-06286224334459
Pubmed

Serpinb3 is overexpressed in the liver in presence of iron overload.

SERPINB3 SERPINB4

6.04e-06286228935635
Pubmed

Overexpression of SERPIN B3 promotes epithelial proliferation and lung fibrosis in mice.

SERPINB3 SERPINB4

6.04e-06286221403642
Pubmed

Molecular cloning of human squamous cell carcinoma antigen 1 gene and characterization of its promoter.

SERPINB3 SERPINB4

6.04e-06286211267667
Pubmed

Epistasis between intracellular cholesterol trafficking-related genes (NPC1 and ABCA1) and Alzheimer's disease risk.

NPC1 ABCA1

6.04e-06286220571217
Pubmed

Squamous Cell Carcinoma Antigen-encoding Genes SERPINB3/B4 as Potentially Useful Markers for the Stratification of HNSCC Tumours.

SERPINB3 SERPINB4

6.04e-06286229491058
Pubmed

The serpin SQN-5 is a dual mechanistic-class inhibitor of serine and cysteine proteinases.

SERPINB3 SERPINB4

6.04e-06286211863458
Pubmed

ABCA1-mediated cholesterol efflux is defective in free cholesterol-loaded macrophages. Mechanism involves enhanced ABCA1 degradation in a process requiring full NPC1 activity.

NPC1 ABCA1

6.04e-06286212215451
Pubmed

IgM-linked SerpinB3 and SerpinB4 in sera of patients with chronic liver disease.

SERPINB3 SERPINB4

6.04e-06286222808225
Pubmed

Tumor-related protein, the squamous cell carcinoma antigen binds to the intracellular protein carbonyl reductase.

SERPINB3 SERPINB4

6.04e-06286220428762
Pubmed

The sperm-associated antigen 6 interactome and its role in spermatogenesis.

NPC1 BTAF1 DCUN1D4 EIF3M SCAF4 REV1

1.05e-0519986631146259
Pubmed

Anti-apoptotic effects of SERPIN B3 and B4 via STAT6 activation in macrophages after infection with Toxoplasma gondii.

SERPINB3 SERPINB4

1.81e-05386222451727
Pubmed

PARP14 correlates with GBM proliferation and poor prognosis by elevating expression of SAMD/SAMD9L.

SAMD9 PARP14

1.81e-05386237612499
Pubmed

ABCA1-dependent mobilization of lysosomal cholesterol requires functional Niemann-Pick C2 but not Niemann-Pick C1 protein.

NPC1 ABCA1

1.81e-05386222179027
Pubmed

MicroRNA-122a Regulates Zonulin by Targeting EGFR in Intestinal Epithelial Dysfunction.

EGFR HP

1.81e-05386228641303
Pubmed

Diagnostic and prognostic role of SCCA-IgM serum levels in hepatocellular carcinoma (HCC).

SERPINB3 SERPINB4

1.81e-05386224635038
Pubmed

Heparin enhances serpin inhibition of the cysteine protease cathepsin L.

SERPINB3 SERPINB4

1.81e-05386219959474
Pubmed

Differential regulation of ATP binding cassette protein A1 expression and ApoA-I lipidation by Niemann-Pick type C1 in murine hepatocytes and macrophages.

NPC1 ABCA1

1.81e-05386217553802
Pubmed

Serpin B3/B4, activated by STAT3, promote survival of squamous carcinoma cells.

SERPINB3 SERPINB4

1.81e-05386219070595
Pubmed

A murine ortholog of the human serpin SCCA2 maps to chromosome 1 and inhibits chymotrypsin-like serine proteinases.

SERPINB3 SERPINB4

1.81e-0538629828132
Pubmed

A serine proteinase inhibitor locus at 18q21.3 contains a tandem duplication of the human squamous cell carcinoma antigen gene.

SERPINB3 SERPINB4

1.81e-0538627724531
Pubmed

Differentially expressed proteins in human breast cancer cells sensitive and resistant to paclitaxel.

SERPINB3 SERPINB4

1.81e-05386224898082
Pubmed

A nonredundant role for mouse Serpinb3a in the induction of mucus production in asthma.

SERPINB3 SERPINB4

1.81e-05386221126757
Pubmed

m6 A reader YTHDF3 triggers the progression of hepatocellular carcinoma through the YTHDF3/m6 A-EGFR/STAT3 axis and EMT.

EGFR YTHDF3

1.81e-05386237449789
Pubmed

Uteroglobin suppresses SCCA gene expression associated with allergic asthma.

SERPINB3 SERPINB4

1.81e-05386215677460
Pubmed

C3 glomerulopathy-associated CFHR1 mutation alters FHR oligomerization and complement regulation.

CFHR2 CFHR5

1.81e-05386223728178
Pubmed

RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2.

FOXL2 RYR2 ITPR2

1.88e-052186331712577
Pubmed

Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics.

NUSAP1 SYNE1 RYR2

3.23e-052586338877142
Pubmed

Correction of apolipoprotein A-I-mediated lipid efflux and high density lipoprotein particle formation in human Niemann-Pick type C disease fibroblasts.

NPC1 ABCA1

3.61e-05486217020879
Pubmed

Serum SCCA, Cyfra 21-1, EGFR and Cyclin D1 levels in patients with oral squamous cell carcinoma.

EGFR SERPINB3

3.61e-05486220586028
Pubmed

Serpin squamous cell carcinoma antigen inhibits UV-induced apoptosis via suppression of c-JUN NH2-terminal kinase.

SERPINB3 SERPINB4

3.61e-05486216549498
Pubmed

Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.

RYR2 ITPR2

3.61e-05486219120137
Pubmed

The physical and genetic map surrounding the Lyst gene on mouse chromosome 13.

LYST RYR2

3.61e-0548629070932
Pubmed

Identification and characterization of the cynomolgus monkey chromodomain gene cynCDY, an orthologue of the human CDY gene family.

CDY2A CDY1

3.61e-05486212149400
Pubmed

Squamous cell carcinoma antigen 1 promotes caspase-8-mediated apoptosis in response to endoplasmic reticulum stress while inhibiting necrosis induced by lysosomal injury.

SERPINB3 SERPINB4

3.61e-05486221576355
Pubmed

A long-range restriction map of deletion interval 6 of the human Y chromosome: a region frequently deleted in azoospermic males.

CDY2A CDY1

3.61e-0548629806824
Pubmed

PEA3 is necessary for optimal epidermal growth factor receptor-stimulated matrix metalloproteinase expression and invasion of ovarian tumor cells.

EGFR MMP14

3.61e-05486217475671
Pubmed

Inhibitory mechanism of a cross-class serpin, the squamous cell carcinoma antigen 1.

SERPINB3 SERPINB4

3.61e-05486212949073
Pubmed

Liver X receptor activation enhances cholesterol loss from the brain, decreases neuroinflammation, and increases survival of the NPC1 mouse.

NPC1 ABCA1

3.61e-05486218160655
Pubmed

Epidermal growth factor receptor regulates MT1-MMP and MMP-2 synthesis in SiHa cells via both PI3-K/AKT and MAPK/ERK pathways.

EGFR MMP14

3.61e-05486219820359
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PHKB TOMM70 CACNA2D1 MAP1A IQGAP2 NEGR1 SYNE1 SVIL GEMIN5 ACTR3B SPECC1 UTRN ITPR2

4.88e-051431861337142655
Pubmed

Factor H-related proteins determine complement-activating surfaces.

CFHR2 CFHR5

6.01e-05586225979655
Pubmed

Association between GWAS-identified lung adenocarcinoma susceptibility loci and EGFR mutations in never-smoking Asian women, and comparison with findings from Western populations.

EGFR DCBLD1

6.01e-05586228025329
Pubmed

Retroposition of autosomal mRNA yielded testis-specific gene family on human Y chromosome.

CDY2A CDY1

6.01e-05586210192397
Pubmed

Genetic variations and treatments that affect the lifespan of the NPC1 mouse.

NPC1 ABCA1

6.01e-05586218077828
Pubmed

HIV types, groups, subtypes and recombinant forms: errors in replication, selection pressure and quasispecies.

CD207 CCR5

6.01e-05586222286874
Pubmed

The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.

IQGAP2 EGFR TRPM7 NBEAL2 DCBLD1 SLC39A10 PARP14 SPECC1

8.47e-0556986830639242
Pubmed

Epidermal EGFR controls cutaneous host defense and prevents inflammation.

EGFR CD207

9.01e-05686223966300
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR2 ITPR2

9.01e-05686223463619
Pubmed

Dimerization of complement factor H-related proteins modulates complement activation in vivo.

CFHR2 CFHR5

9.01e-05686223487775
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR2 ITPR2

9.01e-05686225966694
Pubmed

Sequence and Expression of Complement Factor H Gene Cluster Variants and Their Roles in Age-Related Macular Degeneration Risk.

CFHR2 CFHR5

9.01e-05686227196323
Pubmed

The NEI/NCBI dbGAP database: genotypes and haplotypes that may specifically predispose to risk of neovascular age-related macular degeneration.

CFHR2 CFHR5

9.01e-05686218541031
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR2 ITPR2

9.01e-05686220519450
Pubmed

Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways.

NPC1 ABCA1

9.01e-05686217148552
Pubmed

Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implications.

CFHR2 CFHR5

9.01e-05686217438673
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR2 ITPR2

9.01e-05686216844763
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

TRPM7 RYR2 ITPR2

1.16e-043886330786075
Pubmed

SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice.

SYNE1 UTRN

1.26e-04786219509342
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH2 DNAH8

1.26e-0478629256245
Pubmed

Abnormal phospholipid composition impairs HDL biogenesis and maturation in mice lacking Abca1.

ABCA1 EGFR

1.26e-04786212859204
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR2 ITPR2

1.26e-04786211860456
Pubmed

The carboxyterminus of the ATP-binding cassette transporter A1 interacts with a beta2-syntrophin/utrophin complex.

ABCA1 UTRN

1.26e-04786212054535
Pubmed

Ontogenesis and regulation of cholesterol metabolism in the central nervous system of the mouse.

NPC1 ABCA1

1.26e-04786214643015
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH2 DNAH8

1.26e-04786231178125
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

PHKB EGFR GEMIN5 BTAF1 PARP14

1.50e-0420286533005030
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

PEF1 EGFR TMLHE TNRC6A EIF3M YTHDF3 RYR2

1.52e-0446286731138677
Pubmed

Epidermal growth factor receptor-deficient mice have delayed primary endochondral ossification because of defective osteoclast recruitment.

EGFR MMP14

1.68e-04886215456762
Pubmed

Mammalian chromodomain proteins: their role in genome organisation and expression.

CDY2A CDY1

1.68e-04886210655032
Pubmed

Signaling through the EGF receptor controls lung morphogenesis in part by regulating MT1-MMP-mediated activation of gelatinase A/MMP2.

EGFR MMP14

1.68e-04886211865039
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR2 ITPR2

1.68e-04886219033399
Pubmed

Enriching the Housing Environment for Mice Enhances Their NK Cell Antitumor Immunity via Sympathetic Nerve-Dependent Regulation of NKG2D and CCR5.

CCR5 LYST

1.68e-04886228082402
Pubmed

Previously uncharacterized histone acetyltransferases implicated in mammalian spermatogenesis.

CDY2A CDY1

1.68e-04886212072557
Pubmed

Update of the human and mouse SERPIN gene superfamily.

SERPINB8 SERPINB3 SERPINB4

1.68e-044386324172014
Pubmed

Epidemiological approach to identifying genetic predispositions for atypical hemolytic uremic syndrome.

CFHR2 CFHR5

2.15e-04986220059470
Pubmed

Stress-induced production of chemokines by hair follicles regulates the trafficking of dendritic cells in skin.

CD207 CCR5

2.15e-04986222729248
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

PTN DNAH2 DNAH8

2.19e-04478638812413
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

NPC1 PDE8A TRPM7 SLC39A10 LYST DMXL1 ITPR2

2.58e-0450486734432599
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

NUSAP1 PHKB TOMM70 EGFR SVIL TNRC6A SLC39A10 PAF1 UTRN ITPR2

2.66e-041049861027880917
Pubmed

Comparative mapping in the beige-satin region of mouse chromosome 13.

LYST RYR2

2.68e-04108629027500
InteractionCOA5 interactions

SERPINB8 EGFR SERPINB3 SERPINB4

4.37e-0627834int:COA5
InteractionPKD2L2 interactions

TRPM7 SERPINB3 SERPINB4

1.09e-0511833int:PKD2L2
InteractionOR13C3 interactions

SERPINB8 MAP1A SERPINB3 SERPINB4

1.27e-0535834int:OR13C3
Cytoband18q21.3

SERPINB3 SERPINB4

1.89e-041186218q21.3
Cytoband1q31.3

CFHR2 CFHR5

4.09e-04168621q31.3
Cytoband16q22.2

HP CMTR2

7.82e-042286216q22.2
GeneFamilySerpin peptidase inhibitors

SERPINB8 SERPINB3 SERPINB4

2.88e-0437633739
GeneFamilyWD repeat domain containing|BEACH domain containing

NBEAL2 LYST

4.23e-0496321230
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CFHR2 HP CFHR5

1.03e-03576331179
GeneFamilyDyneins, axonemal

DNAH2 DNAH8

1.57e-0317632536
GeneFamilyWD repeat domain containing

NBEAL2 GEMIN5 CFAP57 LYST DMXL1

2.18e-03262635362
GeneFamilyEndogenous ligands|Matrix metallopeptidases

MMP21 MMP14

3.14e-0324632891
CoexpressionRAO_BOUND_BY_SALL4_ISOFORM_A

PHKB ABCA1 SERPINB3 SERPINB4 RGS9 SPECC1 DMXL1

5.58e-06210857MM958
CoexpressionLAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_CELLS_GLOMERULAR_CAPILLARIES

CACNA2D1 PDE8A SASH1 SYNE1 SVIL UTRN

5.69e-06137856M39241
CoexpressionJAK2_DN.V1_UP

PTN MYO1A PCDHGA9 SERPINB3 SERPINB4 KRT85

2.95e-05183856M2873
CoexpressionRAO_BOUND_BY_SALL4_ISOFORM_A

PHKB ABCA1 SERPINB3 RGS9 SPECC1 DMXL1

4.10e-05194856M2517
CoexpressionSAUL_SEN_MAYO

IQGAP2 EGFR SERPINB3 SERPINB4 MMP14

5.10e-05123855MM16098
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

NPC1 PTN CACNA2D1 MYO1A EGFR KANK4 DCBLD1 HMGCS2 MMP14 DCUN1D4 RYR2 ITPR2

2.60e-057408212gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasDevelopingGonad_e18.5_ovary_emap-12283_top-relative-expression-ranked_1000

FOXL2 TRPM7 COG7 TMLHE TNRC6A GEMIN5 HMGCS2 MMP14 UTRN RYR2 DMXL1 ITPR2

4.23e-057788212gudmap_developingGonad_e18.5_ovary_1000
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

FOXL2 TRPM7 COG7 TMLHE GEMIN5 HMGCS2 MMP14 DNAH8 UTRN RYR2 DMXL1 ITPR2

5.21e-057958212gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlasparathyroid gland

PTN ANOS1 FOXL2 IQGAP2 TRPM7 ARSK DNAH2 KANK4

5.84e-05347828parathyroid gland
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4|TCGA-Pancreas / Sample_Type by Project: Shred V9

CACNA2D1 ABCA1 SASH1 NEGR1 LRRTM3 UTRN ITPR2

6.98e-0818486767164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

NPC1 SYNE1 MMP21 BTAF1 CFAP57 UTRN

2.52e-07135866ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCellAT1|World / shred by cell class for parenchyma

NUSAP1 ANOS1 SERPINB8 SERPINB3 SERPINB4 NBEAL2

2.23e-061968662bc487f8a109a6961ebff111dec79c2227ea60ac
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAP1A FAM81B SYNE1 DNAH2 ODAD2 CFAP57

2.23e-06196866d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAP1A FAM81B SYNE1 DNAH2 ODAD2 CFAP57

2.36e-06198866ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial-gliogenic/outer_RGCs_and_astrocytes|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

PTN ANOS1 IQGAP2 LRRTM3 SPECC1 ITPR2

2.50e-06200866792fef1f3e47ce5c131fedfad55075fc254aeead
ToppCellP15-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

NPC1 MAP1A NEGR1 NBEAL2 CMTR2

1.81e-051678655c3d0763f73628c71c71f9883556bb4f1639f3cc
ToppCellSigmoid-Macrophage-Macrophage|Macrophage / Region, Cell class and subclass

ABCA1 SASH1 IQGAP2 MMP14 UTRN

1.87e-05168865bb16e135b6ae0d66615420b61edd6f62f2a3233c
ToppCellfacs-Heart-LV-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D1 EGFR HP ARSK MMP14

1.92e-05169865849a8f8509c58d65462a09c84d58b6ecdc8934f5
ToppCelldroplet-Spleen-nan-21m-Myeloid-macrophage_dendritic_cell_progenitor|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPC1 EGFR TMLHE CCR5 HMGCS2

1.92e-051698657962165cab84af73d20b56eb70b1ed87c94025ef
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic-mature_NK_T_cell|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

IQGAP2 SYNE1 CCR5 RGS9 BTN3A1

2.15e-0517386536a471576a9d2325066bb14c2f2cd89c67b92915
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NUSAP1 PTN EGFR SERPINB3 SERPINB4

2.27e-051758659142ed8ca2f1c0c518deb21988221406f62fe38c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SASH1 EGFR SYNE1 RGS9 UTRN

2.33e-05176865327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTN ANOS1 NEGR1 SYNE1 SVIL

2.46e-051788650fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

CACNA2D1 SVIL LRRTM3 SLC39A10 RYR2

2.74e-05182865287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAP1A FAM81B DNAH2 ODAD2 CFAP57

3.04e-0518686576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LVRN PTN EGFR NEGR1 MMP14

3.04e-051868657582b5154d8e5a4434817b5ab77a10b789ea2288
ToppCellILEUM-inflamed-(3)_MNP-(3)_moDC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

NPHP3 CD207 UTRN SCAF4 ITPR2

3.12e-051878650099def970fbc828756fbf853eca2ce77b8cd342
ToppCellCiliated_cells-B-IPF_03|World / lung cells shred on cell class, cell subclass, sample id

MAP1A FAM81B NEGR1 ODAD2 CFAP57

3.12e-051878656fa38dbccca36bc7a4fef46de74c6688f599f421
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

ABCA1 IQGAP2 TNRC6A LYST ITPR2

3.12e-05187865f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellMonocytes-M2-like_CD16+_macrophages|Monocytes / Immune cells in Kidney/Urine in Lupus Nephritis

ANOS1 ABCA1 IQGAP2 MMP14 ITPR2

3.12e-0518786559e31c51183ed4c9a3d0792c8005ea3a12b28dfa
ToppCelldroplet-Marrow-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PDE8A SYNE1 DNAH8 LYST REV1

3.12e-0518786514c239af77116d28d511dea754b6150d20488080
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA2D1 NEGR1 SYNE1 ANGPT4 RYR2

3.28e-051898657ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA2D1 EGFR NEGR1 SYNE1 SPECC1

3.36e-051908651121eb607a984c59fbffe7220837fc178745aa55
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

MAP1A FAM81B SYNE1 ODAD2 CFAP57

3.36e-051908659ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MAP1A FAM81B SYNE1 ODAD2 CFAP57

3.36e-05190865833481ace2800354712e2ce709d5cdfd0aed3d42
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA2D1 EGFR NEGR1 SYNE1 SPECC1

3.36e-05190865048b581e3f7ea9fc2f87c0532974bba85c7292c2
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

MAP1A FAM81B DNAH2 ODAD2 CFAP57

3.36e-051908657031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellcellseq2-Epithelial-Epithelial_Airway|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAM81B SERPINB4 DNAH2 ODAD2 CFAP57

3.36e-0519086517829f4de31b3d9e4d71ba4817d18842aa699773
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTN CACNA2D1 NEGR1 SYNE1 RYR2

3.45e-051918657853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

MAP1A FAM81B SYNE1 ODAD2 CFAP57

3.54e-05192865be592e661367affced9ebe80849b466e6adb3a34
ToppCellmulticiliated|World / shred by cell class for turbinate

MAP1A FAM81B DNAH2 ODAD2 CFAP57

3.54e-051928650f89ea0deb651ca11531c51ee94e0233608d22ea
ToppCellcontrol-Lymphoid-CTL|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IQGAP2 SYNE1 DCBLD1 CCR5 UTRN

3.62e-0519386589d407a88b5956559a589425b89b3eb8dc78e1dd
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

MAP1A FAM81B SYNE1 ODAD2 CFAP57

3.62e-051938650b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellNS-critical-d_07-13-Epithelial-Ciliated|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAP1A FAM81B DNAH2 ODAD2 CFAP57

3.71e-051948651ae8a10e508e672e6677f0e3c986ac30d05adeb3
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A FAM81B DNAH2 ODAD2 CFAP57

3.81e-05195865649fd2336e963f6a150d182a53ad5dd838ca80b1
ToppCellNasal_Brush|World / Tissue, Lineage and Cell class of Lung Cells from 10X

PTN SERPINB3 SERPINB4 HMGCS2 PARP14

3.81e-051958657509b980b6b293df02bec619ef5b83a6c7b49c03
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A FAM81B DNAH2 ODAD2 CFAP57

3.81e-05195865129ad5f4253ecb1a8477cc38773e6e91ea9570b0
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A FAM81B DNAH2 ODAD2 CFAP57

3.81e-051958653e70ee987d66d450062d5df3d7c733ccc7344470
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAP1A SYNE1 DNAH2 ODAD2 CFAP57

3.81e-051958653486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAP1A FAM81B DNAH2 ODAD2 CFAP57

3.90e-0519686527b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellfacs-Brain_Non-Myeloid|facs / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTN SASH1 MAP1A SYNE1 UTRN

4.00e-05197865a1f7eec1aca03432caa8fe817ff6d24b29d4062d
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-Macrophages|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ABCA1 SASH1 PARP14 UTRN ITPR2

4.00e-0519786510190b877bf46ba2163d203df9dd3b498c66e52f
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAP1A FAM81B SYNE1 ODAD2 CFAP57

4.00e-051978656865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A FAM81B SYNE1 DNAH2 ODAD2

4.00e-0519786591637bdeab85024b5a02d1066f76cb803a2d6420
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAP1A FAM81B SYNE1 ODAD2 CFAP57

4.00e-0519786571fea4aa6ce96c7693fa94792d08770622873850
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A FAM81B SYNE1 DNAH2 ODAD2

4.00e-0519786522c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-6_mon|organoid_Paulsen_bioRxiv / Sample Type, Dataset, Time_group, and Cell type.

ABCA1 EGFR MMP14 SPECC1 ITPR2

4.00e-0519786558b957efd006f43c2fe55071d5c6d06c2e367e72
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A FAM81B SYNE1 DNAH2 ODAD2

4.00e-051978653bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAP1A FAM81B SYNE1 ODAD2 CFAP57

4.00e-05197865e453d085182364ca347cbcc9dc995c62c3353016
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A FAM81B SYNE1 DNAH2 ODAD2

4.00e-0519786587db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

MAP1A FAM81B SYNE1 ODAD2 CFAP57

4.00e-05197865d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MYO1A NEGR1 SYNE1 ANGPT4 RYR2

4.00e-05197865ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCellCOVID_vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

SYNE1 CCR5 RGS9 UTRN BTN3A1

4.00e-05197865d4dfb3b561d0783cdbee4e8d27009ad81df695cb
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NPC1 SYNE1 BTAF1 PARP14 UTRN

4.19e-05199865f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellNasal_Brush-Epithelial-Goblet_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

PDE8A SERPINB3 SERPINB4 SVIL PARP14

4.19e-05199865aa6f1390283617c7f9aaf91d379024832ea24a9e
ToppCellBiopsy_Control_(H.)-Epithelial-Basal|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

ANOS1 EGFR SERPINB3 SERPINB4 LRRTM3

4.19e-051998656a274a5db02c55bbf31d602b9d5c8394241acdca
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HP SYNE1 NBEAL2 SVIL LYST

4.19e-05199865b7af2b4fe6866cc8c78cf0f78390aab1b1b389ba
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PTN ANOS1 EGFR NEGR1 MMP14

4.19e-0519986595d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCellNasal_Brush-Epithelial-Goblet_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

PDE8A SERPINB3 SERPINB4 SVIL PARP14

4.19e-051998652ac716f887687b5109fb9feced75d5c62646a268
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PTN CACNA2D1 ANOS1 NEGR1 MMP14

4.29e-05200865747c61d4e0b746278ae1f45ca4cd556c6961c76a
ToppCellmild-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

NPC1 SAMD9 SYNE1 RGS9 UTRN

4.29e-05200865d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCellBronchial_Brush-Epithelial-Basal_2|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

PTN ANOS1 EGFR SERPINB3 SERPINB4

4.29e-052008651fa29a9f42987549a75dffeb177099458f7cca88
ToppCellBronchial_Brush-Epithelial-Basal_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

PTN ANOS1 EGFR SERPINB3 SERPINB4

4.29e-052008657595eb2a8af3de879ecaa71f3d96f890e13b59ce
ToppCell10x3'2.3-week_17-19-Mesenchymal_fibro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PTN CACNA2D1 ANOS1 NEGR1 MMP14

4.29e-05200865de1d193f773f4e2927baa6fc38d29754b015c6e6
ToppCellCOVID-19-Myeloid-MoAM2,_CCL18|Myeloid / Condition, Lineage and Cell class

NPC1 ABCA1 IQGAP2 MMP14 ITPR2

4.29e-05200865a60346c5ea7a3dae1ad3c5dc6c6eca65b64c6888
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HP SYNE1 NBEAL2 SVIL LYST

4.29e-05200865808571d74bb5c4d765ff13fc9393f88020d4e90d
ToppCellLPS_only-Mesenchymal_myocytic|LPS_only / Treatment groups by lineage, cell group, cell type

PTN MAP1A NEGR1 SYNE1 RYR2

4.29e-052008658bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal-Basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PTN ANOS1 EGFR SERPINB3 SERPINB4

4.29e-052008650594ca7bc313b73e1dc800cf058f8f798b0284cb
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NEGR1 DNAH2 MMP21 DNAH8

4.76e-05103864eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCellRV-03._Atrial_Cardiomyocyte|RV / Chamber and Cluster_Paper

MYO1A SVIL LRRTM3 RYR2

5.13e-0510586449e16b11f16e83a7d17d162c14bce991201bcc2a
ToppCellRV-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

MYO1A SVIL LRRTM3 RYR2

9.20e-051228641cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCellTCGA-Peripheral_Nervous_System-Primary_Tumor-Paraganglioma-Paraganglioma-3|TCGA-Peripheral_Nervous_System / Sample_Type by Project: Shred V9

SYNE1 SVIL BTAF1 CMTR2

1.36e-04135864ac20133d4a36f48338b45bffb13e842cb66f83ad
ToppCellCOVID-19_Mild|World / 5 Neutrophil clusters in COVID-19 patients

MAP1A ADGRE3 CFAP57 BTN3A1

2.14e-041528642ff0980dfd8d430cca14649151d856edef115720
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 CFHR2 HP SYNE1

2.25e-0415486471ffc23a2e02e27cabbdbeaa622e59e9f4a4cd9d
ToppCellfacs-Marrow-B-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUSAP1 CFHR2 HP SYNE1

2.25e-0415486446155f36d3983f637b55d7525b675c8828f6ab2e
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HP SYNE1 SVIL LYST

2.43e-041578640673c7161c25feceee8f1e5fd237171576c42c6b
ToppCellfacs-Marrow-B-cells-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HP SYNE1 SVIL LYST

2.43e-04157864d307d0b48af35e0e1af41ecd3ebf91be8fd29dc0
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PTN EGFR SERPINB3 SERPINB4

2.55e-0415986422427ad4ad2e797e4664e7a7b0514094f22a18b2
ToppCellCiliated_cells-A-HP_01|World / lung cells shred on cell class, cell subclass, sample id

FAM81B DNAH2 ODAD2 CFAP57

2.55e-041598640c65ae6140abd48c79b04758a6217709ddd15385
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFHR2 SERPINB8 CD207 CCR5

2.67e-0416186476c993a4533362db2250c88b3ee3ede55362d54e
ToppCellBasal_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CACNA2D1 PCDHGA9 SERPINB3 SERPINB4

2.80e-04163864679e25e5548d157d49a73057a3b5617dccda260f
ToppCellfacs-Pancreas-Exocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1A EGFR GDAP2 GEMIN5

2.80e-04163864132aece9c79499b4bb3c2bde68d3d7202e1d8772
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HP FAM81B DNAH2 ODAD2

2.86e-04164864e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 SASH1 NEGR1 MMP14

2.86e-04164864758e85e2f5e7236b345e16c78344d5e0bf17d8dc
ToppCellPND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LVRN NUSAP1 IQGAP2 IL20RA

2.93e-0416586426c750f10f6401752e2e63d91dc844c81b29d735
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SASH1 NEGR1 CCR5 MMP14

3.00e-04166864b3d9b61847c6c96b8cb28b8a6aeda52f43c706ab
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HP SYNE1 SVIL LYST

3.21e-04169864a5964aef04093b460bbe29d5e2e7389f8fd2d46f
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP1A HP GDAP2 HMGCS2

3.21e-0416986415a9183c838cc6384d7f5dfeae3d30602964c9b3
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTN KANK4 IL20RA LRRTM3

3.21e-0416986487116c33c5ca8cb1862e103e5607b1df4d264569
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HP SYNE1 SVIL LYST

3.21e-04169864e0076aa61b4ef3f836f5750005d0469d3982eb6d
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HP SYNE1 SVIL LYST

3.21e-041698642341eddfedaad8cee779c37bb87f7def058588ca
ToppCellfacs-Marrow-Granulocytes-18m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HP SYNE1 SVIL LYST

3.21e-0416986494871936ccfc73b56d425373b989b87c059d4493
ToppCellfacs-Large_Intestine-Proximal-18m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SERPINB8 DNAH2 GEMIN5 CFAP57

3.28e-0417086445de83a2231208b8e1f21061d0b91644b4a3ba93
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 SASH1 PARP14 MMP14

3.28e-04170864067657ca7fcf5a0ffbd168b5c4609a30ca508f22
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HP SYNE1 SVIL LYST

3.36e-04171864ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCellfacs-Marrow-Granulocytes|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HP SYNE1 SVIL LYST

3.36e-041718641701dedf0c18751db6c9fee3d93fff150ed0e17f
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HP SYNE1 SVIL LYST

3.36e-0417186497ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ANOS1 NEGR1 KRT85 SVIL

3.36e-04171864fe0665c5ca01b0b2cc8f20d64587f0847c3d215c
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA1 SASH1 NEGR1 MMP14

3.43e-041728647295bf3ae21a61dd6bcfa0dfb7a37d0f3e8f94ab
Diseaseextrahepatic cholestasis (biomarker_via_orthology)

PTN ABCA1 HMGCS2

1.42e-0517833DOID:13619 (biomarker_via_orthology)
Diseasetype 1 diabetes mellitus (biomarker_via_orthology)

EGFR HP CCR5

2.01e-0519833DOID:9744 (biomarker_via_orthology)
DiseaseColorectal Neoplasms

NUSAP1 ABCA1 FOXL2 EGFR TRPM7 SYNE1

1.34e-04277836C0009404
DiseaseNeoplasm Invasiveness

EGFR TRPM7 HMGCS2 SLC39A10 MMP14

1.75e-04184835C0027626
Diseasehousehold income

NPC1 PTGES2 SAMD9 TRPM7 NEGR1 TNRC6A

2.21e-04304836EFO_0009695
DiseaseC3 glomerulopathy

CFHR2 CFHR5

2.78e-049832C4087273
DiseaseCoronavirus infectious disease (implicated_via_orthology)

EGFR CCR5

2.78e-049832DOID:0080599 (implicated_via_orthology)
DiseaseAutosomal Recessive Polycystic Kidney Disease

NPHP3 EGFR

2.78e-049832C0085548
DiseaseCognitive impairment

RYR2 DMXL1

4.23e-0411832HP_0100543
Diseasebitter alcoholic beverage consumption measurement

NPC1 NEGR1 TNRC6A DNAH2

5.50e-04133834EFO_0010092
DiseaseAtherosclerosis

NPC1 ABCA1 HP

6.23e-0459833C0004153
DiseaseAtherogenesis

NPC1 ABCA1 HP

6.23e-0459833C1563937
Diseasepimelic acid measurement, 3-methyladipic acid measurement

ABCA1 KANK4

6.96e-0414832EFO_0010449, EFO_0010524
DiseaseSpermatogenic Failure, Nonobstructive, Y-Linked

CDY2A CDY1

9.14e-0416832C1839071
DiseaseSpermatogenic failure, Y-linked, 2

CDY2A CDY1

9.14e-0416832cv:C1839071
DiseaseSPERMATOGENIC FAILURE, Y-LINKED, 2

CDY2A CDY1

9.14e-0416832415000
Diseasesusceptibility to mononucleosis measurement

DNAH2 DNAH8 RYR2

9.84e-0469833EFO_0008403
Diseasecomplex trait

ABCA1 TNRC6A KANK4 DCBLD1 CFHR5

1.02e-03271835EFO_0010578
Diseaselaryngeal squamous cell carcinoma (is_marker_for)

FOXL2 EGFR

1.30e-0319832DOID:2876 (is_marker_for)
DiseaseEsophageal Neoplasms

EGFR SERPINB3 MMP14

1.40e-0378833C0014859
DiseaseMalignant neoplasm of esophagus

EGFR SERPINB3 MMP14

1.40e-0378833C0546837
Diseasehaptoglobin measurement

HP CMTR2

1.59e-0321832EFO_0004640
DiseaseRenal glomerular disease

ANOS1 NPHP3

1.90e-0323832C0268731
DiseaseGlomerulopathy Assessment

ANOS1 NPHP3

1.90e-0323832C4521256
DiseaseUterine leiomyoma

SYNE1 DNAH2 REV1

2.18e-0391833HP_0000131
Diseaseperipheral arterial disease, traffic air pollution measurement

ABCA1 NEGR1 UTRN ITPR2

2.22e-03194834EFO_0004265, EFO_0007908
Diseasedigestive system infectious disorder

NPC1 ITPR2

2.43e-0326832MONDO_0043424
Diseasechronic obstructive pulmonary disease (is_marker_for)

EGFR HP CCR5

2.62e-0397833DOID:3083 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
EQFIKWKQSIGQNYS

ARSK

486

Q6UWY0
VGQYKLNWKNCKGIT

FAM200B

281

P0CF97
QSKYKVINKDQWCNV

DCUN1D4

241

Q92564
KNLIAKWKKQGYENL

BUD31

86

P41223
QDKNGNTQYLVRWKG

CDY1

16

Q9Y6F8
QDKNGNTQYLVRWKG

CDY2A

16

Q9Y6F7
KKNSAKNPWQEYNYL

COG7

521

P83436
AGYFLWQQQEEKKTQ

BTN3A1

266

O00481
KWIKQYTGINAINQK

ACTR3B

251

Q9P1U1
SYQVKGWKLTQQQFV

ABCA1

1316

O95477
AKNFSYGKPLNNEWQ

CMTR2

31

Q8IYT2
NALLKWCQKKTQGYA

SPECC1

966

Q5M775
NYDKLGWKKLNQQLE

LVRN

661

Q6Q4G3
QYQFWKNFQTLKIVI

CCR5

186

P51681
QKKNLELYSQWQKSG

DMXL1

91

Q9Y485
NKYWKFNNQKLKVEP

MMP14

481

P50281
KENYNFLNQKMNYKW

RGS9

141

O75916
WKKQFGAECKYQFQA

PTN

91

P21246
YSAQKQYWKAKQAKQ

ITPR2

66

Q14571
FLYNKDVNGKVVLWK

GDAP2

46

Q9NXN4
YQDGQLQVKVYWKKT

ANOS1

436

P23352
KKDQALEQKYWALGQ

MAP1A

1546

P78559
YTLNDKKQWINKAVG

HP

66

P00738
EWYKGEKKLFNGQQG

NEGR1

256

Q7Z3B1
SKKINWIVQYAQNKD

EURL

91

Q9NYK6
QQNKLLETKWQFYQN

KRT85

146

P78386
ANQELQQLFYQWKCK

MYO1A

816

Q9UBC5
NHCVKYNVDQKWQKF

CFAP57

36

Q96MR6
YDTLNAWKQNLNKVK

EIF3M

351

Q7L2H7
TSYRKKIQNQWKQAG

HMGCS2

271

P54868
FKGNAYWKVVNDKDK

MMP21

521

Q8N119
EGINGKVAYKFWKIN

PCDHGA9

271

Q9Y5G4
WQGIYYAKKKNGDNI

PDE8A

286

O60658
YNAPFKKNIQNWVYK

DNAH8

1466

Q96JB1
KYNIKLKWTNQQKLY

CFHR2

216

P36980
AKFPFYEKNKKGWQN

FOXL2

86

P58012
KLKPWGQSKENNYLN

NUSAP1

376

Q9BXS6
KFIQQWKNLFQQYDR

PEF1

181

Q9UBV8
VQYFIYGQKKWLNKS

IL20RA

71

Q9UHF4
ENNKKWTENQFLKYR

FAM81B

311

Q96LP2
QAWEKEFINFVKNYK

NPC1

581

O15118
IQNPDLWNSYQAKKK

PARP14

1651

Q460N5
NWNVKNKASKGYEEN

PAF1

296

Q8N7H5
NKNLCYANTINWKKL

EGFR

466

P00533
QDGVNWLAFLNKYKL

BTAF1

1271

O14981
VQNYWSKQKNIKGVK

CACNA2D1

716

P54289
ENGTVNFQRNWKDYK

ANGPT4

336

Q9Y264
KNNIQLKWRNDGKLY

CFHR5

516

Q9BXR6
QWIDLVFGYKQKGKA

LYST

3356

Q99698
GQYVKKIQELLQEQW

KANK4

561

Q5T7N3
ISNYLAWFQQKPGKA

IGKV1-16

51

P04430
NNSKWKTYKGIVNNE

DCBLD1

351

Q8N8Z6
KKFLQLGWNIIYGFN

DNAH2

3996

Q9P225
GNYKVNQKSIKIAWA

SCAF4

566

O95104
YKQQRGKQKWFMKQN

SLC39A10

521

Q9ULF5
WKKIIAYQQKLLNYF

RYR2

4481

Q92736
DDIKNALQFIKQYWK

PHKB

596

Q93100
YKQEFDDVQGKWNKL

UTRN

986

P46939
YNALPAWKQVNLKKA

SVIL

2196

O95425
IQGNAKKALLKWVQY

SYNE1

176

Q8NF91
LKYNQFKGLNQLTWL

LRRTM3

76

Q86VH5
LAKKYARWFQQKPGQ

IGLV3-27

46

P01718
VQWKKFGNAEQLYKQ

NPHP3

996

Q7Z494
QNYNNKIWEQSKKFS

SAMD9

326

Q5K651
EENVVKIQAFWKGYK

IQGAP2

691

Q13576
YWQIQKLVKYLKGGN

ODAD2

451

Q5T2S8
AQKDLGYLQQWLKAF

NBEAL2

16

Q6ZNJ1
GNKYWLMLNEKEAQQ

PTGES2

206

Q9H7Z7
LVNAIYFKGQWEKKF

SERPINB3

176

P29508
LVNAIYFKGKWNEQF

SERPINB8

161

P50452
YKLLNWAYQQVQQNK

STEAP1B

171

Q6NZ63
LSQQVQKQYQKWFRE

ADGRE3

601

Q9BY15
LIGYTVKNAWKNNVF

CLDND2

111

Q8NHS1
ILQVVSQGWKYFKGN

CD207

191

Q9UJ71
INNYNPKDFDWNLKN

YTHDF3

401

Q7Z739
EWQYYQNKILKGKAA

REV1

466

Q9UBZ9
GVCNNYWKEKRQNDK

TRIM51

356

Q9BSJ1
SIKNNYDVKNFWQGV

GEMIN5

411

Q8TEQ6
NKYFWQNFRKNQKGI

SASH1

151

O94885
KKPYWNNEEAESKQN

SNURFL

71

B1AK76
LVNAIYFKGQWENKF

SERPINB4

176

P48594
YFKGQWENKFKKENT

SERPINB4

181

P48594
YQNRAAAFEQLQKWK

TOMM70

156

O94826
AQDLWPKQGKKNYFQ

ZNF98

91

A6NK75
VKWQQFNNRAYSKNK

SMNDC1

176

O75940
NWLVKNSYEGQKQKV

TMLHE

131

Q9NVH6
PSKYNYKNVNMWNKN

TNRC6A

1011

Q8NDV7
YKNVNMWNKNVPNGN

TNRC6A

1016

Q8NDV7
KVNQKIKVWFSDYFN

TRPM7

911

Q96QT4