Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

POU4F2 BSX ONECUT1 ONECUT2 POU3F2

3.82e-06560105GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

POU4F2 BSX ONECUT1 ONECUT2 POU3F2

4.03e-06566105GO:0001216
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

POU4F2 HEY2 BSX ONECUT1 ONECUT2 POU3F2

9.76e-061244106GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

POU4F2 HEY2 BSX ONECUT1 ONECUT2 POU3F2

1.11e-051271106GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

POU4F2 HEY2 BSX ONECUT1 ONECUT2 POU3F2

2.03e-051412106GO:0000981
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

POU4F2 HEY2 BSX ONECUT1 ONECUT2 POU3F2

2.45e-051459106GO:0000977
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

POU4F2 MECP2

7.52e-0483102GO:1990841
GeneOntologyMolecularFunctionhistone deacetylase binding

HEY2 MECP2

2.33e-03147102GO:0042826
GeneOntologyMolecularFunctionchromatin binding

POU4F2 ONECUT1 MECP2

4.98e-03739103GO:0003682
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity, RNA polymerase II-specific

POU4F2 HEY2

1.06e-02320102GO:0001227
GeneOntologyMolecularFunctionDNA-binding transcription repressor activity

POU4F2 HEY2

1.10e-02326102GO:0001217
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

POU4F2 HEY2 BSX ONECUT1 ONECUT2 MECP2 POU3F2

6.23e-071390107GO:0045944
GeneOntologyBiologicalProcesspositive regulation of developmental growth

POU4F2 HEY2 MECP2 POU3F2

3.44e-06238104GO:0048639
GeneOntologyBiologicalProcesscell fate commitment

HEY2 ONECUT1 ONECUT2 POU3F2

1.38e-05338104GO:0045165
GeneOntologyBiologicalProcesspositive regulation of growth

POU4F2 HEY2 MECP2 POU3F2

1.39e-05339104GO:0045927
GeneOntologyBiologicalProcessregulation of growth

POU4F2 HEY2 HRG MECP2 POU3F2

1.61e-05777105GO:0040008
GeneOntologyBiologicalProcessregulation of developmental growth

POU4F2 HEY2 MECP2 POU3F2

3.26e-05421104GO:0048638
GeneOntologyBiologicalProcessregulation of cell-matrix adhesion

ONECUT1 ONECUT2 HRG

3.62e-05141103GO:0001952
GeneOntologyBiologicalProcessendocrine system development

ONECUT1 ONECUT2 POU3F2

5.38e-05161103GO:0035270
GeneOntologyBiologicalProcessnegative regulation of smooth muscle cell differentiation

HEY2 MECP2

5.81e-0524102GO:0051151
GeneOntologyBiologicalProcessatrioventricular valve morphogenesis

HEY2 AXIN2

7.94e-0528102GO:0003181
GeneOntologyBiologicalProcessgland development

BSX ONECUT1 ONECUT2 POU3F2

9.77e-05558104GO:0048732
GeneOntologyBiologicalProcessatrioventricular valve development

HEY2 AXIN2

1.04e-0432102GO:0003171
GeneOntologyBiologicalProcessNotch signaling pathway

HEY2 ONECUT1 MECP2

1.18e-04210103GO:0007219
GeneOntologyBiologicalProcessnegative regulation of developmental process

POU4F2 HEY2 AXIN2 HRG MECP2

1.41e-041220105GO:0051093
GeneOntologyBiologicalProcessgrowth

POU4F2 HEY2 HRG MECP2 POU3F2

1.49e-041235105GO:0040007
GeneOntologyBiologicalProcessaortic valve morphogenesis

HEY2 AXIN2

1.55e-0439102GO:0003180
GeneOntologyBiologicalProcessregulation of cell-substrate adhesion

ONECUT1 ONECUT2 HRG

2.08e-04254103GO:0010810
GeneOntologyBiologicalProcessregulation of locomotion

POU4F2 ONECUT1 ONECUT2 HRG MECP2

2.10e-041327105GO:0040012
GeneOntologyBiologicalProcessaortic valve development

HEY2 AXIN2

2.16e-0446102GO:0003176
GeneOntologyBiologicalProcessregulation of transcription regulatory region DNA binding

POU4F2 HEY2

2.16e-0446102GO:2000677
GeneOntologyBiologicalProcesscell-matrix adhesion

ONECUT1 ONECUT2 HRG

2.49e-04270103GO:0007160
GeneOntologyBiologicalProcesssemi-lunar valve development

HEY2 AXIN2

2.56e-0450102GO:1905314
GeneOntologyBiologicalProcessregulation of smooth muscle cell differentiation

HEY2 MECP2

2.99e-0454102GO:0051150
GeneOntologyBiologicalProcesscirculatory system development

POU4F2 HEY2 AXIN2 HRG MECP2

3.10e-041442105GO:0072359
GeneOntologyBiologicalProcessheart development

POU4F2 HEY2 AXIN2 MECP2

3.17e-04757104GO:0007507
GeneOntologyBiologicalProcessepithelium development

HEY2 ONECUT1 ONECUT2 AXIN2 POU3F2

3.39e-041469105GO:0060429
GeneOntologyBiologicalProcessendocrine pancreas development

ONECUT1 ONECUT2

3.81e-0461102GO:0031018
GeneOntologyBiologicalProcessheart valve morphogenesis

HEY2 AXIN2

4.07e-0463102GO:0003179
GeneOntologyBiologicalProcessepithelial cell differentiation

HEY2 ONECUT1 ONECUT2 POU3F2

5.38e-04870104GO:0030855
GeneOntologyBiologicalProcessnegative regulation of cell differentiation

POU4F2 HEY2 AXIN2 MECP2

5.50e-04875104GO:0045596
GeneOntologyBiologicalProcessventricular cardiac muscle tissue development

HEY2 MECP2

5.92e-0476102GO:0003229
GeneOntologyBiologicalProcessheart valve development

HEY2 AXIN2

6.23e-0478102GO:0003170
GeneOntologyBiologicalProcessdevelopmental growth

POU4F2 HEY2 MECP2 POU3F2

6.41e-04911104GO:0048589
GeneOntologyBiologicalProcessnegative regulation of muscle cell differentiation

HEY2 MECP2

7.05e-0483102GO:0051148
GeneOntologyBiologicalProcessregulation of cardiac muscle cell apoptotic process

POU4F2 HEY2

7.22e-0484102GO:0010665
GeneOntologyBiologicalProcessnegative regulation of blood vessel endothelial cell migration

HRG MECP2

7.39e-0485102GO:0043537
GeneOntologyBiologicalProcessregulation of striated muscle cell apoptotic process

POU4F2 HEY2

7.92e-0488102GO:0010662
GeneOntologyBiologicalProcesscardiac muscle cell apoptotic process

POU4F2 HEY2

8.28e-0490102GO:0010659
GeneOntologyBiologicalProcessdiencephalon development

MECP2 POU3F2

8.28e-0490102GO:0021536
GeneOntologyBiologicalProcesscell-substrate adhesion

ONECUT1 ONECUT2 HRG

8.43e-04410103GO:0031589
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

ONECUT1 ONECUT2 HRG

8.55e-04412103GO:0090287
GeneOntologyBiologicalProcessstriated muscle cell apoptotic process

POU4F2 HEY2

9.03e-0494102GO:0010658
GeneOntologyBiologicalProcessperipheral nervous system development

ONECUT2 POU3F2

9.81e-0498102GO:0007422
GeneOntologyBiologicalProcesssmooth muscle cell differentiation

HEY2 MECP2

1.00e-0399102GO:0051145
GeneOntologyBiologicalProcesspancreas development

ONECUT1 ONECUT2

1.06e-03102102GO:0031016
GeneOntologyBiologicalProcessastrocyte differentiation

MECP2 POU3F2

1.12e-03105102GO:0048708
GeneOntologyBiologicalProcessnegative regulation of endothelial cell migration

HRG MECP2

1.12e-03105102GO:0010596
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

POU4F2 HRG MECP2 POU3F2

1.26e-031090104GO:0022603
GeneOntologyBiologicalProcessregulation of cell development

POU4F2 HEY2 AXIN2 MECP2

1.28e-031095104GO:0060284
GeneOntologyBiologicalProcessaxis specification

HEY2 AXIN2

1.30e-03113102GO:0009798
GeneOntologyBiologicalProcessregulation of DNA binding

POU4F2 HEY2

1.35e-03115102GO:0051101
GeneOntologyBiologicalProcessnegative regulation of epithelial cell migration

HRG MECP2

1.59e-03125102GO:0010633
GeneOntologyBiologicalProcessregulation of neurogenesis

POU4F2 HEY2 MECP2

1.63e-03515103GO:0050767
GeneOntologyBiologicalProcessresponse to estradiol

POU4F2 MECP2

1.66e-03128102GO:0032355
GeneOntologyBiologicalProcessregulation of cell growth

POU4F2 HRG MECP2

1.67e-03519103GO:0001558
GeneOntologyBiologicalProcessregulation of cell migration

ONECUT1 ONECUT2 HRG MECP2

1.87e-031211104GO:0030334
GeneOntologyBiologicalProcessnegative regulation of transforming growth factor beta receptor signaling pathway

ONECUT1 ONECUT2

1.93e-03138102GO:0030512
GeneOntologyBiologicalProcessregulation of muscle cell apoptotic process

POU4F2 HEY2

2.01e-03141102GO:0010660
GeneOntologyBiologicalProcesslimbic system development

MECP2 POU3F2

2.01e-03141102GO:0021761
GeneOntologyBiologicalProcesscerebral cortex development

MECP2 POU3F2

2.19e-03147102GO:0021987
GeneOntologyBiologicalProcessanimal organ morphogenesis

HEY2 BSX ONECUT2 AXIN2

2.22e-031269104GO:0009887
GeneOntologyBiologicalProcessmuscle cell apoptotic process

POU4F2 HEY2

2.28e-03150102GO:0010657
GeneOntologyBiologicalProcessregulation of cell motility

ONECUT1 ONECUT2 HRG MECP2

2.29e-031280104GO:2000145
GeneOntologyCellularComponentchromatin

POU4F2 HEY2 BSX ONECUT1 ONECUT2 MECP2 POU3F2

8.73e-071480107GO:0000785
GeneOntologyCellularComponenttranscription regulator complex

POU4F2 HEY2 BSX POU3F2

1.20e-04596104GO:0005667
MousePhenoabnormal bile duct development

ONECUT1 ONECUT2

4.81e-0515102MP:0002929
MousePhenopostnatal growth retardation

HEY2 ONECUT1 AXIN2 MECP2 POU3F2

1.90e-04881105MP:0001732
MousePhenoabnormal postnatal growth

HEY2 ONECUT1 AXIN2 MECP2 POU3F2

2.18e-04907105MP:0001731
Domain-

POU4F2 ONECUT1 ONECUT2 POU3F2

7.23e-10271041.10.260.40
DomainLambda_DNA-bd_dom

POU4F2 ONECUT1 ONECUT2 POU3F2

9.78e-1029104IPR010982
DomainHomeobox

POU4F2 BSX ONECUT1 ONECUT2 POU3F2

7.08e-08234105PF00046
DomainHOMEOBOX_1

POU4F2 BSX ONECUT1 ONECUT2 POU3F2

7.39e-08236105PS00027
DomainHOX

POU4F2 BSX ONECUT1 ONECUT2 POU3F2

7.55e-08237105SM00389
DomainHomeobox_dom

POU4F2 BSX ONECUT1 ONECUT2 POU3F2

7.87e-08239105IPR001356
DomainHOMEOBOX_2

POU4F2 BSX ONECUT1 ONECUT2 POU3F2

7.87e-08239105PS50071
Domain-

POU4F2 BSX ONECUT1 ONECUT2 POU3F2

1.83e-072831051.10.10.60
DomainHomeodomain-like

POU4F2 BSX ONECUT1 ONECUT2 POU3F2

4.03e-07332105IPR009057
DomainCUT_dom

ONECUT1 ONECUT2

5.41e-067102IPR003350
DomainCUT

ONECUT1 ONECUT2

5.41e-067102PF02376
DomainCUT

ONECUT1 ONECUT2

5.41e-067102SM01109
DomainCUT

ONECUT1 ONECUT2

5.41e-067102PS51042
DomainPOU_3

POU4F2 POU3F2

3.08e-0516102PS51179
DomainPOU_2

POU4F2 POU3F2

3.08e-0516102PS00465
DomainPou

POU4F2 POU3F2

3.08e-0516102PF00157
DomainPOU_dom

POU4F2 POU3F2

3.08e-0516102IPR000327
DomainPOU_1

POU4F2 POU3F2

3.08e-0516102PS00035
DomainPOU

POU4F2 POU3F2

3.08e-0516102SM00352
DomainPOU

POU4F2 POU3F2

3.49e-0517102IPR013847
DomainHomeobox_CS

POU4F2 BSX POU3F2

1.11e-04186103IPR017970
PathwayPID_ERA_GENOMIC_PATHWAY

POU4F2 AXIN2

4.20e-046472M200
PathwayWP_MECP2_AND_ASSOCIATED_RETT_SYNDROME

MECP2 POU3F2

5.46e-047372M39401
PathwayWP_NEURAL_CREST_DIFFERENTIATION

HEY2 AXIN2

9.62e-049772MM15926
PathwayWP_NEURAL_CREST_DIFFERENTIATION

HEY2 AXIN2

1.04e-0310172M39448
PathwayWP_BREAST_CANCER_PATHWAY

HEY2 AXIN2

2.40e-0315472M39739
PathwayWP_SUDDEN_INFANT_DEATH_SYNDROME_SIDS_SUSCEPTIBILITY_PATHWAYS

MECP2 POU3F2

2.56e-0315972M39373
Pubmed

Onecut 1 and Onecut 2 are potential regulators of mouse retinal development.

POU4F2 ONECUT1 ONECUT2

9.58e-10810321830221
Pubmed

Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development.

POU4F2 ONECUT1 ONECUT2

1.39e-081810325794677
Pubmed

Onecut1 is essential for horizontal cell genesis and retinal integrity.

POU4F2 ONECUT1 ONECUT2

2.27e-082110323926259
Pubmed

Relief of hypoxia by angiogenesis promotes neural stem cell differentiation by targeting glycolysis.

HEY2 AXIN2 POU3F2

4.43e-082610326856890
Pubmed

Notch signaling controls liver development by regulating biliary differentiation.

HEY2 ONECUT1 ONECUT2

4.43e-082610319369401
Pubmed

A census of human transcription factors: function, expression and evolution.

POU4F2 HEY2 BSX ONECUT1 ONECUT2 POU3F2

5.98e-0890810619274049
Pubmed

Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate.

ONECUT1 ONECUT2 AXIN2

6.23e-082910318038450
Pubmed

Dose-dependent regulation of horizontal cell fate by Onecut family of transcription factors.

ONECUT1 ONECUT2

7.44e-08210232790713
Pubmed

The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor.

VGLL3 ONECUT2 AXIN2

9.30e-083310319336002
Pubmed

Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development.

POU4F2 ONECUT1 ONECUT2

2.10e-074310325228773
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

HEY2 BSX ONECUT1 ONECUT2 POU3F2

2.17e-0754410528473536
Pubmed

OC-3, a novel mammalian member of the ONECUT class of transcription factors.

ONECUT1 ONECUT2

2.23e-07310211944891
Pubmed

ONECUT transcription factors induce neuronal characteristics and remodel chromatin accessibility.

ONECUT1 ONECUT2

2.23e-07310231049588
Pubmed

OC-2, a novel mammalian member of the ONECUT class of homeodomain transcription factors whose function in liver partially overlaps with that of hepatocyte nuclear factor-6.

ONECUT1 ONECUT2

2.23e-0731029915796
Pubmed

Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression.

POU4F2 ONECUT1 ONECUT2

3.98e-075310327210758
Pubmed

Cloning and embryonic expression pattern of the mouse Onecut transcription factor OC-2.

ONECUT1 ONECUT2

4.46e-07410212971999
Pubmed

Expression of the alpha7 isoform of hepatocyte nuclear factor (HNF) 4 is activated by HNF6/OC-2 and HNF1 and repressed by HNF4alpha1 in the liver.

ONECUT1 ONECUT2

4.46e-07410215159395
Pubmed

MiR-495 and miR-218 regulate the expression of the Onecut transcription factors HNF-6 and OC-2.

ONECUT1 ONECUT2

7.44e-07510219913497
Pubmed

Expression of a large family of POU-domain regulatory genes in mammalian brain development.

POU4F2 POU3F2

1.12e-0661022739723
Pubmed

Otx2 and Onecut1 promote the fates of cone photoreceptors and horizontal cells and repress rod photoreceptors.

ONECUT1 ONECUT2

1.12e-06610223867227
Pubmed

The Onecut transcription factor HNF-6 (OC-1) is required for timely specification of the pancreas and acts upstream of Pdx-1 in the specification cascade.

ONECUT1 ONECUT2

1.12e-06610212781686
Pubmed

The transcription factor hepatocyte nuclear factor-6/Onecut-1 controls the expression of its paralog Onecut-3 in developing mouse endoderm.

ONECUT1 ONECUT2

1.12e-06610215381696
Pubmed

A CpG mutational hotspot in a ONECUT binding site accounts for the prevalent variant of hemophilia B Leyden.

ONECUT1 ONECUT2

2.08e-06810223472758
Pubmed

Chromosomal organization of mammalian POU domain factors.

POU4F2 POU3F2

2.68e-0691028276396
Pubmed

Isl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cells.

POU4F2 POU3F2

2.68e-06910224643061
Pubmed

Specification of embryonic stem cell-derived tissues into eye fields by Wnt signaling using rostral diencephalic tissue-inducing culture.

POU4F2 AXIN2

2.68e-06910227151576
Pubmed

Onecut Factors and Pou2f2 Regulate the Distribution of V2 Interneurons in the Mouse Developing Spinal Cord.

ONECUT1 ONECUT2

3.34e-061010231231191
Pubmed

Pou2f2 Regulates the Distribution of Dorsal Interneurons in the Mouse Developing Spinal Cord.

ONECUT1 ONECUT2

4.09e-061110231787878
Pubmed

Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program.

ONECUT1 ONECUT2

5.79e-061310222115757
Pubmed

Onecut transcription factors are required for the second phase of development of the A13 dopaminergic nucleus in the mouse.

ONECUT1 ONECUT2

5.79e-061310222102297
Pubmed

The Onecut transcription factors HNF-6/OC-1 and OC-2 regulate early liver expansion by controlling hepatoblast migration.

ONECUT1 ONECUT2

6.76e-061410217936262
Pubmed

Control of liver cell fate decision by a gradient of TGF beta signaling modulated by Onecut transcription factors.

ONECUT1 ONECUT2

6.76e-061410216103213
Pubmed

Onecut factors control development of the Locus Coeruleus and of the mesencephalic trigeminal nucleus.

ONECUT1 ONECUT2

6.76e-061410222534286
Pubmed

Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development.

ONECUT1 ONECUT2

6.76e-061410223213462
Pubmed

ETS factors regulate Vegf-dependent arterial specification.

HEY2 AXIN2

7.80e-061510223830865
Pubmed

Integral bHLH factor regulation of cell cycle exit and RGC differentiation.

POU4F2 ONECUT2

7.80e-061510229770538
Pubmed

Dynamic expression of the Onecut transcription factors HNF-6, OC-2 and OC-3 during spinal motor neuron development.

ONECUT1 ONECUT2

8.91e-061610219800948
Pubmed

The Onecut Transcription Factors Regulate Differentiation and Distribution of Dorsal Interneurons during Spinal Cord Development.

ONECUT1 ONECUT2

8.91e-061610228603487
Pubmed

A cis-regulatory module underlies retinal ganglion cell genesis and axonogenesis.

POU4F2 ONECUT2

1.01e-051710238823017
Pubmed

The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.

ONECUT1 ONECUT2

1.01e-051710216472605
Pubmed

Onecut-dependent Nkx6.2 transcription factor expression is required for proper formation and activity of spinal locomotor circuits.

ONECUT1 ONECUT2

1.14e-051810231969659
Pubmed

Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development.

AXIN2 POU3F2

1.14e-051810237054704
Pubmed

The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling.

HEY2 AXIN2

1.27e-051910220627076
Pubmed

Mammalian Llgl2 is necessary for proper branching morphogenesis during placental development.

HEY2 AXIN2

1.41e-052010221606200
Pubmed

A dynamic gradient of Wnt signaling controls initiation of neurogenesis in the mammalian cortex and cellular specification in the hippocampus.

AXIN2 POU3F2

1.41e-052010217916349
Pubmed

Onecut transcription factors act upstream of Isl1 to regulate spinal motoneuron diversification.

ONECUT1 ONECUT2

1.56e-052110222833130
Pubmed

Role of the Onecut transcription factors in pancreas morphogenesis and in pancreatic and enteric endocrine differentiation.

ONECUT1 ONECUT2

1.71e-052210217400205
Pubmed

Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity.

ONECUT1 ONECUT2

1.71e-052210238160393
Pubmed

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis.

AXIN2 POU3F2

1.88e-052310226371318
Pubmed

Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression.

ONECUT1 ONECUT2

1.88e-052310219805515
Pubmed

Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate.

POU4F2 ONECUT1

2.22e-052510225775587
Pubmed

Vsx1 Transiently Defines an Early Intermediate V2 Interneuron Precursor Compartment in the Mouse Developing Spinal Cord.

ONECUT1 ONECUT2

2.41e-052610228082864
Pubmed

Onecut1 and Onecut2 play critical roles in the development of the mouse retina.

ONECUT1 ONECUT2

2.60e-052710225313862
Pubmed

Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps.

ONECUT1 ONECUT2

2.80e-052810217698011
Pubmed

Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.

POU4F2 ONECUT2

3.22e-053010230127719
Pubmed

Single-cell transcriptional logic of cell-fate specification and axon guidance in early-born retinal neurons.

POU4F2 ONECUT2

3.22e-053010231399471
Pubmed

Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation.

POU4F2 ONECUT2

3.22e-053010229137925
Pubmed

Wnt/β-catenin and Bmp signals control distinct sets of transcription factors in cardiac progenitor cells.

HEY2 AXIN2

3.44e-053110222711842
Pubmed

c-Jun is required for the specification of joint cell fates.

AXIN2 POU3F2

3.44e-053110223475960
Pubmed

Bicaudal C1 promotes pancreatic NEUROG3+ endocrine progenitor differentiation and ductal morphogenesis.

ONECUT1 AXIN2

3.67e-053210225715394
Pubmed

Negative regulation of Shh levels by Kras and Fgfr2 during hair follicle development.

HEY2 AXIN2

4.15e-053410223123965
Pubmed

Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression.

POU4F2 ONECUT1

4.15e-053410226949938
Pubmed

A cellular and molecular mosaic establishes growth and differentiation states for cranial sensory neurons.

ONECUT1 ONECUT2

4.40e-053510226988119
Pubmed

Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors.

HEY2 ONECUT1

4.66e-053610225715395
Pubmed

Myocardial β-Catenin-BMP2 signaling promotes mesenchymal cell proliferation during endocardial cushion formation.

HEY2 AXIN2

5.20e-053810230201295
Pubmed

Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation.

POU4F2 AXIN2

6.37e-054210230485816
Pubmed

Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies.

VGLL3 BSX

7.65e-054610221102462
Pubmed

A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation.

AXIN2 POU3F2

9.05e-055010222365545
Pubmed

Prox1 ablation in hepatic progenitors causes defective hepatocyte specification and increases biliary cell commitment.

ONECUT1 ONECUT2

9.05e-055010224449835
Pubmed

The TAF10-containing TFIID and SAGA transcriptional complexes are dispensable for early somitogenesis in the mouse embryo.

HEY2 AXIN2

9.79e-055210228893950
Pubmed

Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme.

HEY2 AXIN2

1.44e-046310230916783
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

VGLL3 ONECUT1 ONECUT2 MECP2

2.53e-04120310429180619
Pubmed

Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter.

HEY2 AXIN2

2.68e-048610235103284
InteractionKDM5B interactions

VGLL3 ONECUT2 AXIN2 MECP2

1.17e-07100104int:KDM5B
InteractionONECUT2 interactions

ONECUT2 MECP2

4.65e-067102int:ONECUT2
InteractionKRTAP6-1 interactions

POU4F2 HEY2 VGLL3

1.52e-05103103int:KRTAP6-1
InteractionKRTAP9-2 interactions

POU4F2 VGLL3 AXIN2

4.58e-05149103int:KRTAP9-2
InteractionCYSRT1 interactions

POU4F2 HEY2 VGLL3 HRG

7.60e-05511104int:CYSRT1
InteractionKRTAP1-1 interactions

POU4F2 HEY2 VGLL3

1.44e-04219103int:KRTAP1-1
GeneFamilyCUT class homeoboxes and pseudogenes

ONECUT1 ONECUT2

7.92e-06992527
GeneFamilyPOU class homeoboxes and pseudogenes

POU4F2 POU3F2

5.54e-052392523
CoexpressionDESCARTES_FETAL_EYE_HORIZONTAL_CELLS

ONECUT1 ONECUT2

3.01e-0522102M40179
CoexpressionHU_FETAL_RETINA_HORIZONTAL

ONECUT1 ONECUT2

1.01e-0440102M39265
CoexpressionHALLMARK_WNT_BETA_CATENIN_SIGNALING

HEY2 AXIN2

1.12e-0442102M5895
CoexpressionDESCARTES_MAIN_FETAL_HORIZONTAL_CELLS

ONECUT1 ONECUT2

1.40e-0447102M40096
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBML1

ONECUT1 ONECUT2 POU3F2

2.18e-04328103M39064
CoexpressionSTEARMAN_LUNG_CANCER_EARLY_VS_LATE_DN

AXIN2 POU3F2

2.53e-0463102M10880
CoexpressionSTEARMAN_LUNG_CANCER_EARLY_VS_LATE_DN

AXIN2 POU3F2

2.94e-0468102MM1036
CoexpressionBENPORATH_EED_TARGETS

POU4F2 ONECUT1 ONECUT2 POU3F2

4.58e-041059104M7617
CoexpressionBENPORATH_ES_WITH_H3K27ME3

POU4F2 ONECUT1 ONECUT2 POU3F2

5.57e-041115104M10371
CoexpressionLIM_MAMMARY_LUMINAL_MATURE_DN

HEY2 AXIN2

5.62e-0494102M2580
CoexpressionLIM_MAMMARY_LUMINAL_MATURE_DN

HEY2 AXIN2

5.74e-0495102MM1328
CoexpressionTANAKA_METHYLATED_IN_ESOPHAGEAL_CARCINOMA

ONECUT1 ONECUT2

6.61e-04102102M14455
CoexpressionDESCARTES_FETAL_LIVER_HEPATOBLASTS

ONECUT1 ONECUT2 HRG

7.71e-04505103M40234
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

POU4F2 ONECUT2 POU3F2

1.22e-03591103M2019
CoexpressionKRAS.PROSTATE_UP.V1_DN

VGLL3 POU3F2

1.26e-03141102M2901
CoexpressionMIKKELSEN_MEF_HCP_WITH_H3K27ME3

POU4F2 ONECUT2 POU3F2

1.28e-03601103MM866
CoexpressionGSE7459_UNTREATED_VS_IL6_TREATED_ACT_CD4_TCELL_DN

BSX ONECUT2

1.33e-03145102M463
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_1000

HEY2 VGLL3 AXIN2 MECP2

1.86e-0476994gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_1000

HEY2 AXIN2 MECP2

4.31e-0437793gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_1000_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_top-relative-expression-ranked_500

HEY2 VGLL3 AXIN2

4.76e-0439093gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_EmbryoidBody_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000

ONECUT1 ONECUT2 AXIN2 POU3F2

4.83e-0498694PCBC_EB_fibroblast_1000
ToppCellTCGA-Bile_Duct|World / Sample_Type by Project: Shred V9

ONECUT1 ONECUT2 HRG

3.48e-06140103ca8a0ccbc2f501b759864fe9bb06dc8b44b6b31f
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POU4F2 HEY2 VGLL3

9.41e-061951039fea1ddb68da83ca43dd8006c9e51295b1817f0e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-midbrain/hindbrain_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

POU4F2 ONECUT1 ONECUT2

9.70e-06197103c7078f6fcf27319ba8c5ebe700bcae7f1e7e39c1
ToppCellBrain_organoid-organoid_Tanaka_cellReport-1m-Neuronal-Interneuron|1m / Sample Type, Dataset, Time_group, and Cell type.

POU4F2 ONECUT1 ONECUT2

1.01e-05200103fc839e9c33ea1d4ee0f42f21fd32a54e7cbe1f5a
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligodendroglioma-7|TCGA-Brain / Sample_Type by Project: Shred V9

ONECUT1 ONECUT2

2.22e-04101102385e67efc555e3543ddb02cda7edd88babb83b42
ToppCellE16.5-samps-Mesenchymal-Pericyte|E16.5-samps / Age Group, Lineage, Cell class and subclass

HEY2 ONECUT1

4.75e-04148102e697a7fb037873c9b11703d1bf836a69fc276e23
ToppCellE16.5-samps-Mesenchymal-Pericyte-pericyte_A|E16.5-samps / Age Group, Lineage, Cell class and subclass

HEY2 ONECUT1

4.75e-04148102c87fe2373418ec0cfe37279003d1c4df4c0d0aac
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_C|E18.5-samps / Age Group, Lineage, Cell class and subclass

HEY2 HRG

4.95e-041511023f2abaa42876ce7a71d934ff16abe0cab0991a05
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT2 HRG

4.95e-04151102cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT2 HRG

5.55e-04160102c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT2 HRG

5.76e-041631021c4de36cf8cdaabb981cda5c7ce7e5ae7b4280e3
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT2 HRG

5.76e-0416310203d9fa615d9d02ef98e20f28a10aaa6894dd4960
ToppCellfacs-Marrow-B-cells-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEY2 ONECUT2

5.90e-04165102361a605d8f833d9ec54b120480dce397da35f9c3
ToppCelldroplet-Limb_Muscle-nan-3m-Myeloid-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AXIN2 POU3F2

5.97e-041661020a7992bc673fca546636563ec3fc17a4298ab6b1
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ONECUT2 HRG

6.04e-04167102743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ONECUT2 HRG

6.04e-041671021adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VGLL3 POU3F2

6.12e-04168102af82e07d1eec51fc6530155f37addbce6221885d
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-5|TCGA-Bladder / Sample_Type by Project: Shred V9

POU4F2 POU3F2

6.19e-041691029c4e83fe8225d16173a103bf5a57b17d623be923
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

VGLL3 POU3F2

6.48e-04173102789ab8b2709f4b8728e3733bc72744e9d92ea5ea
ToppCellCOVID-19-kidney-PCT-S3-2|kidney / Disease (COVID-19 only), tissue and cell type

ONECUT1 HRG

6.56e-041741025aa2fb631505600f37d2b87b02def7be139dc262
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HEY2 VGLL3

6.56e-04174102412ccc099028a372b9d953363984c2da54b2187f
ToppCell10x3'2.3-week_17-19-Neuro-stroma-schwann_cells|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

VGLL3 POU3F2

6.63e-041751028b010220cdfb680ec839572f4933adfb85045ea6
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_ductal_cel|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VGLL3 ONECUT1

6.63e-0417510278b453e220218c84557f244ef7a760e4a1952761
ToppCelldroplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_ductal_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VGLL3 ONECUT1

6.63e-04175102c1a8a55af825d5913095f919fa860828df9c273e
ToppCell10x3'2.3-week_17-19-Neuro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

VGLL3 POU3F2

6.63e-041751020b579aeadcc06be83627391c0b01bd8605fdbdf3
ToppCell10x3'2.3-week_17-19-Neuro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

VGLL3 POU3F2

6.63e-04175102bbce8b1a160b414c0bf643c21c4e5e78fbccb7e1
ToppCellEntopeduncular-Endothelial-MURAL|Entopeduncular / BrainAtlas - Mouse McCarroll V32

HEY2 VGLL3

6.71e-04176102b8e52bec78876562a25f0b0de502aa9372b28bd2
ToppCellCOVID-19-kidney-PCT-S3-2|COVID-19 / Disease (COVID-19 only), tissue and cell type

ONECUT1 HRG

6.71e-04176102b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCellEntopeduncular-Endothelial-MURAL-M1(Rgs5Acta2)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

HEY2 VGLL3

6.71e-0417610210c1f31c27e54b70f58f0b0086ac74dee2ce4197
ToppCellfacs-Marrow-B-cells-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEY2 ONECUT2

6.71e-041761025f9ae5eb45603ed0422a3a993ecdbe2ce05d6e45
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

VGLL3 POU3F2

6.78e-0417710259cf56c385c324f0844f20003d2b5049a2791e45
ToppCellfacs-Marrow-B-cells-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEY2 ONECUT2

6.78e-0417710235d42b07d9c31528bf59199e361bb8a3bfbe3b75
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HEY2 VGLL3

6.86e-041781029fc5688cf705a74398d24e10e0aab4758612e72b
ToppCellStriatum-Endothelial-MURAL-M1(Rgs5Acta2)|Striatum / BrainAtlas - Mouse McCarroll V32

HEY2 VGLL3

6.94e-0417910299167ac678cae5c35b1d4f4a81b32000437c00c2
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEY2 ONECUT2

6.94e-04179102b44e2d53b82c3c141bfc6539054b19708200a0d9
ToppCellStriatum-Endothelial-MURAL|Striatum / BrainAtlas - Mouse McCarroll V32

HEY2 VGLL3

6.94e-041791023d58babf44e47462c3d4129dd2e94a2339fd7ce0
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VGLL3 AXIN2

7.01e-041801025b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VGLL3 AXIN2

7.01e-04180102da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VGLL3 AXIN2

7.01e-0418010250758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Mesenchymal-Mes-Pericyte|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HEY2 VGLL3

7.09e-04181102634a4f4e5942473e60d08d0b0936407b04bc6b7c
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HEY2 VGLL3

7.09e-04181102098dbb3e0ff531c9720a233123250c1e39a97d4c
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Mesenchymal-Mes-Pericyte-Peri_L1-6_MUSTN1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HEY2 VGLL3

7.09e-04181102c2938cf1f5d4875be07a56a1f36c94f8eab37d99
ToppCellCerebellum-Endothelial-MURAL|Cerebellum / BrainAtlas - Mouse McCarroll V32

HEY2 VGLL3

7.17e-04182102b2f03f61aebb5920595fed8b9d6799a09353419b
ToppCellCerebellum-Endothelial-MURAL-M1(Rgs5Acta2)|Cerebellum / BrainAtlas - Mouse McCarroll V32

HEY2 VGLL3

7.17e-04182102da61e7cb2537c567968d8bd8baf537ecdff0ab18
ToppCelldroplet-Heart-nan-18m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT1 POU3F2

7.25e-041831021701c8c212f1fdb6e4764375542a203e19753d14
ToppCelldroplet-Lung-nan-3m-Mesenchymal-fibroblast_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VGLL3 AXIN2

7.33e-0418410289ac32e374a4379e4a6c6ea7603b1378b77c147f
ToppCelldroplet-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VGLL3 AXIN2

7.33e-041841024df6027fa635996c1eddb920f88a5265772df1cd
ToppCelldroplet-Heart-nan-18m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT1 POU3F2

7.41e-04185102c61267cfadea018794f7964904445787629a40d1
ToppCelldroplet-Heart-nan-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ONECUT1 POU3F2

7.41e-041851023a592719d5643011954f89d5bb61a5e94682b68e
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

HEY2 VGLL3

7.48e-04186102cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HEY2 VGLL3

7.73e-04189102d0c7549be4f77520c23dddf4f94d0fcad0081e37
ToppCellhuman_hepatoblastoma-Hepatic_Stellate_cells|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)

HEY2 VGLL3

7.89e-0419110278c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-cycling_ENCC/glia|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POU4F2 HEY2

8.05e-041931024f4f430d7e1b65e19ca829f55ca93edeb6c1c85d
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-Pericytes|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HEY2 VGLL3

8.05e-0419310247d189bac0ef4df2f5c6dd987e46aca85bd7e2af
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEY2 VGLL3

8.14e-04194102bf34737ae2dc218f890fbb9201c308b324415749
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEY2 VGLL3

8.14e-041941024ebed7a6731b88c8359860072cbeba355a7e90ac
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

HEY2 VGLL3

8.14e-04194102a7731378f44ca1a229311686caf5740c742d21ba
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEY2 VGLL3

8.14e-04194102b35e33439b6d3b5d69147e617224d2c8fd056223
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

ONECUT1 POU3F2

8.30e-041961020767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

POU4F2 VGLL3

8.30e-041961029afd0a7135028a446f06bb68f334e79b8f171b45
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEY2 VGLL3

8.30e-041961028114e98923096c54b6834f21550c3061bab6773d
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEY2 VGLL3

8.30e-04196102184104cbea0461dd2757668ab9755948ac7b585a
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Mesenchymal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HEY2 VGLL3

8.30e-04196102bebb20dc210576101c317011e3afb59798f5d255
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_monocytic-monocyte|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HEY2 VGLL3

8.39e-04197102b2f4d7c301c0b24003374923b31d6d058e40b213
ToppCellTracheal-NucSeq-Stromal-Schwann|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VGLL3 ONECUT1

8.39e-04197102c1b2a3fbd5f4aeb3555d8c372efc86f1052e7c65
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

ONECUT1 ONECUT2

8.39e-041971022d92b0483d57541aee382dda80e42cf66e813d6b
ToppCellTracheal-NucSeq-Stromal-Schwann-Schwann_nonmyelinating|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

VGLL3 ONECUT1

8.39e-041971025c88a97e8e23a5cd61885acbe1ef339ae6a1e35a
ToppCell5'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HEY2 VGLL3

8.47e-0419810252ddc1f1ed4ac4c3bac794c90b8feb03e3c221c4
ToppCellmetastatic_Brain-Fibroblasts|metastatic_Brain / Location, Cell class and cell subclass

HEY2 VGLL3

8.56e-0419910263eb2106bb6e2e33d020628583536c8d96662c84
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VGLL3 AXIN2

8.56e-04199102c1760581c34b81d1d92c67500a1c8944e9cc6dad
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Perivascular_fibroblast|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

VGLL3 AXIN2

8.56e-04199102dfc5c7a4a093baa7158dd8d4d29a870d9c469a3f
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuronal-Neuron|6m / Sample Type, Dataset, Time_group, and Cell type.

POU4F2 ONECUT2

8.64e-04200102b5019b9d48f32cffd4645a5c0f3e0ac504ea8019
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-OPC_related-Oligodendrocyte/OPC|10w / Sample Type, Dataset, Time_group, and Cell type.

VGLL3 POU3F2

8.64e-04200102345f1eac498cc87fd7bf08e7312608b2d6fe1dd7
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-OPC_related|10w / Sample Type, Dataset, Time_group, and Cell type.

VGLL3 POU3F2

8.64e-042001028f5d98f962ddd8c4658c89ff8a2894de1228562a
DrugNSC123116

ONECUT1 ONECUT2

9.53e-0611102CID000275966
DrugBeclomethasone dipropionate [5534-09-8]; Up 200; 7.6uM; MCF7; HT_HG-U133A

HEY2 ONECUT1 ONECUT2

7.32e-051971034403_UP
DrugProcarbazine hydrochloride [366-70-1]; Up 200; 15.6uM; MCF7; HT_HG-U133A

HEY2 ONECUT1 HRG

7.43e-051981033533_UP
DrugPropoxycaine hydrochloride [550-83-4]; Up 200; 12uM; MCF7; HT_HG-U133A

HEY2 ONECUT2 POU3F2

7.43e-051981033583_UP
DrugFenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; PC3; HT_HG-U133A

ONECUT1 ONECUT2 HRG

7.66e-052001033714_UP
DrugClobetasol propionate [25122-46-7]; Up 200; 8.6uM; MCF7; HT_HG-U133A

HEY2 VGLL3 HRG

7.66e-052001036095_UP
Drugcalcium hydroxide

ONECUT1 ONECUT2

1.09e-0436102CID000014777
DrugO-EC

ONECUT2 HRG

4.86e-0476102CID006338557
Drug3-(phosphonomethyl)pyridine-2-carboxylic acid

POU4F2 ONECUT1

5.52e-0481102CID000001629
DrugMPC-1304

ONECUT1 ONECUT2

6.37e-0487102CID000002225
DrugAC1L1AGT

AXIN2 HRG

1.03e-03111102CID000000982
DrugCT-26

ONECUT2 AXIN2

1.61e-03139102CID003034916
Drugpanobinostat

HEY2 VGLL3 ONECUT2 AXIN2

1.85e-031333104ctd:C496932
Drughistidinate

ONECUT1 HRG

2.51e-03174102CID000000773
DrugMonensin sodium salt [22373-78-0]; Up 200; 5.8uM; MCF7; HT_HG-U133A

ONECUT2 HRG

2.54e-031751024726_UP
Drug(+)-Isoproterenol (+)-bitartrate salt [14638-70-1]; Up 200; 11uM; PC3; HT_HG-U133A

VGLL3 HRG

2.74e-031821026663_UP
DrugMebendazole [31431-39-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A

VGLL3 ONECUT2

2.95e-031891022300_UP
Drugretinoic acid; Up 200; 1uM; PC3; HT_HG-U133A

VGLL3 MECP2

3.01e-031911021211_UP
DrugNiclosamide

HEY2 AXIN2

3.01e-03191102ctd:D009534
DrugOrlistat; Up 200; 10uM; PC3; HT_HG-U133A

ONECUT2 HRG

3.04e-031921026388_UP
DrugEthaverine hydrochloride [985-13-7]; Down 200; 9.2uM; MCF7; HT_HG-U133A

ONECUT2 MECP2

3.04e-031921023375_DN
DrugTetrahydroalstonine [6474-90-4]; Up 200; 11.4uM; MCF7; HT_HG-U133A

POU4F2 HEY2

3.08e-031931022748_UP
DrugChlorprothixene hydrochloride [6469-93-8]; Down 200; 11.4uM; MCF7; HT_HG-U133A

ONECUT2 MECP2

3.08e-031931025291_DN
DrugAjmaline [4360-12-7]; Up 200; 12.2uM; MCF7; HT_HG-U133A

ONECUT2 POU3F2

3.08e-031931022899_UP
DrugDecamethonium bromide [541-22-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A

POU4F2 ONECUT1

3.11e-031941024174_DN
DrugBenfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; MCF7; HT_HG-U133A

ONECUT2 POU3F2

3.11e-031941022621_UP
DrugCarbachol [51-83-2]; Up 200; 21.8uM; MCF7; HT_HG-U133A

ONECUT2 MECP2

3.11e-031941025342_UP
DrugPilocarpine nitrate [148-72-1]; Up 200; 14.8uM; PC3; HT_HG-U133A

HRG MECP2

3.11e-031941026741_UP
DrugBenfluorex hydrochloride [23642-66-2]; Up 200; 10.4uM; PC3; HT_HG-U133A

VGLL3 ONECUT2

3.11e-031941026727_UP
DrugRoxithromycin [80214-83-1]; Down 200; 4.8uM; PC3; HT_HG-U133A

VGLL3 MECP2

3.11e-031941024192_DN
DrugTrichlormethiazide [133-67-5]; Down 200; 10.6uM; PC3; HT_HG-U133A

VGLL3 ONECUT2

3.14e-031951024198_DN
DrugCyclacillin [3485-14-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A

HEY2 ONECUT2

3.14e-031951024358_DN
DrugEstradiol-17 beta [50-28-2]; Up 200; 14.6uM; MCF7; HT_HG-U133A

HEY2 ONECUT2

3.14e-031951022653_UP
DrugPyridoxine hydrochloride [58-56-0]; Up 200; 19.4uM; PC3; HT_HG-U133A

MECP2 POU3F2

3.14e-031951025813_UP
DrugProbucol [23288-49-5]; Up 200; 7.8uM; MCF7; HT_HG-U133A

HEY2 POU3F2

3.14e-031951025261_UP
DrugFinasteride [98319-26-7]; Up 200; 10.8uM; PC3; HT_HG-U133A

ONECUT2 HRG

3.14e-031951024300_UP
Drugwortmannin from Penicillium funiculosum; Up 200; 0.01uM; MCF7; HT_HG-U133A

ONECUT1 ONECUT2

3.14e-031951025240_UP
Druggenistein; Down 200; 1uM; MCF7; HG-U133A

ONECUT1 HRG

3.14e-03195102268_DN
DrugChicago sky blue 6B [2610-05-1]; Up 200; 4uM; MCF7; HT_HG-U133A

HEY2 ONECUT2

3.14e-031951023266_UP
DrugLithocholic acid [434-13-9]; Down 200; 10.6uM; MCF7; HT_HG-U133A

MECP2 POU3F2

3.14e-031951024373_DN
DrugAtropine sulfate monohydrate [5908-99-6]; Down 200; 5.8uM; MCF7; HT_HG-U133A

ONECUT2 MECP2

3.14e-031951022761_DN
DrugCholecalciferol [67-97-0]; Up 200; 10.4uM; MCF7; HT_HG-U133A

POU4F2 ONECUT2

3.14e-031951023298_UP
DrugChlorambucil [305-03-3]; Down 200; 13.2uM; MCF7; HT_HG-U133A

HEY2 MECP2

3.14e-031951024345_DN
DrugSulfapyridine [144-83-2]; Up 200; 16uM; HL60; HT_HG-U133A

VGLL3 ONECUT1

3.14e-031951022538_UP
DrugBetulinic acid [472-15-1]; Down 200; 8.8uM; MCF7; HT_HG-U133A

POU4F2 ONECUT1

3.14e-031951024181_DN
DrugMepenzolate bromide [76-90-4]; Up 200; 9.6uM; MCF7; HT_HG-U133A

ONECUT1 ONECUT2

3.14e-031951023829_UP
DrugPrimaquine diphosphate [63-45-6]; Up 200; 8.8uM; PC3; HT_HG-U133A

HRG MECP2

3.14e-031951024263_UP
DrugPindolol [13523-86-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A

HEY2 ONECUT2

3.14e-031951026834_UP
Drugtetraethylenepentamine pentahydrochloride; Down 200; 10uM; MCF7; HG-U133A

ONECUT2 MECP2

3.14e-03195102405_DN
DrugPNU-0230031 [267429-39-0]; Up 200; 10uM; PC3; HT_HG-U133A

ONECUT2 HRG

3.17e-031961024288_UP
DrugIdoxuridine [54-42-2]; Down 200; 11.2uM; PC3; HT_HG-U133A

ONECUT2 MECP2

3.17e-031961024200_DN
DrugCefoxitin sodium salt [33564-30-6]; Up 200; 8.8uM; HL60; HT_HG-U133A

ONECUT2 HRG

3.17e-031961022735_UP
DrugDO 897/99; Up 200; 8.2uM; MCF7; HT_HG-U133A

POU4F2 ONECUT2

3.17e-031961022877_UP
DrugLomefloxacin hydrochloride [98079-52-8]; Up 200; 10.4uM; PC3; HT_HG-U133A

ONECUT2 HRG

3.17e-031961024281_UP
Drug0173570-0000 [211245-44-2]; Up 200; 10uM; PC3; HT_HG-U133A

POU4F2 HRG

3.17e-031961023690_UP
DrugIndapamide [26807-65-8]; Up 200; 10.6uM; MCF7; HT_HG-U133A

POU4F2 ONECUT2

3.17e-031961022322_UP
DrugBiperiden hydrochloride [1235-82-1]; Down 200; 11.4uM; MCF7; HT_HG-U133A

POU4F2 ONECUT2

3.17e-031961025279_DN
DrugCitalopram hydrobromide [59729-32-7]; Up 200; 1uM; PC3; HT_HG-U133A

ONECUT1 HRG

3.17e-031961023820_UP
DrugAmrinone [60719-84-8]; Up 200; 21.4uM; HL60; HT_HG-U133A

ONECUT2 POU3F2

3.17e-031961022724_UP
DrugCarbenoxolone disodium salt [7421-40-1]; Up 200; 6.6uM; PC3; HT_HG-U133A

VGLL3 ONECUT2

3.17e-031961024093_UP
DrugGemfibrozil [25812-30-0]; Up 200; 16uM; MCF7; HT_HG-U133A

HEY2 HRG

3.17e-031961022277_UP
DrugAcacetin [480-44-4]; Up 200; 14uM; PC3; HT_HG-U133A

ONECUT2 HRG

3.17e-031961024324_UP
Drugdaunorubicin HCl; Up 200; 1uM; PC3; HT_HG-U133A

HRG MECP2

3.17e-031961027511_UP
DrugDicumarol [66-76-2]; Down 200; 11.8uM; PC3; HT_HG-U133A

VGLL3 MECP2

3.17e-031961023766_DN
DrugNorfloxacin [70458-96-7]; Up 200; 12.6uM; MCF7; HT_HG-U133A

POU4F2 HRG

3.17e-031961025985_UP
DrugDemeclocycline hydrochloride [64-73-3]; Up 200; 8uM; PC3; HT_HG-U133A

HRG POU3F2

3.17e-031961023706_UP
DrugF0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A

HEY2 ONECUT2

3.17e-031961026396_DN
DrugFinasteride [98319-26-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A

POU4F2 ONECUT1

3.17e-031961024766_DN
DrugTetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; PC3; HT_HG-U133A

HEY2 VGLL3

3.17e-031961025757_UP
Drugprednisolone; Down 200; 1uM; MCF7; HG-U133A

ONECUT1 HRG

3.17e-03196102265_DN
DrugPHA-00745360 [351320-33-7]; Down 200; 10uM; MCF7; HT_HG-U133A

HEY2 POU3F2

3.17e-031961024381_DN
DrugAlfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; PC3; HT_HG-U133A

ONECUT2 POU3F2

3.17e-031961024644_UP
DrugIndapamide [26807-65-8]; Up 200; 10.6uM; PC3; HT_HG-U133A

ONECUT2 HRG

3.17e-031961024335_UP
DrugEstriol [50-27-1]; Up 200; 13.8uM; MCF7; HT_HG-U133A

HEY2 VGLL3

3.17e-031961023563_UP
DrugEnoxacin [74011-58-8]; Up 200; 12.4uM; MCF7; HT_HG-U133A

HEY2 ONECUT2

3.17e-031961025251_UP
DrugRolitetracycline [751-97-3]; Up 200; 7.6uM; MCF7; HT_HG-U133A

ONECUT2 MECP2

3.17e-031961025331_UP
DrugMethionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; MCF7; HT_HG-U133A

HEY2 ONECUT1

3.17e-031961024151_DN
DrugZardaverine [101975-10-4]; Down 200; 15uM; MCF7; HT_HG-U133A

ONECUT2 MECP2

3.17e-031961024793_DN
Drugradicicol; Down 200; 0.1uM; MCF7; HT_HG-U133A

ONECUT2 POU3F2

3.17e-031961025947_DN
Drugstaurosporine; Down 200; 0.01uM; MCF7; HG-U133A

POU4F2 MECP2

3.17e-03196102425_DN
DrugTremorine dihydrochloride [300-68-5]; Up 200; 15uM; MCF7; HT_HG-U133A

ONECUT2 MECP2

3.17e-031961026273_UP
DrugEpitiostanol [2363-58-8]; Down 200; 13uM; PC3; HT_HG-U133A

VGLL3 ONECUT2

3.17e-031961024204_DN
DrugNaproxen [22204-53-1]; Up 200; 17.4uM; PC3; HT_HG-U133A

VGLL3 HRG

3.20e-031971021828_UP
DrugArcaine sulfate [14923-17-2]; Down 200; 14.8uM; PC3; HT_HG-U133A

ONECUT2 MECP2

3.20e-031971026629_DN
DrugDicloxacillin sodium salt [13412-64-1]; Up 200; 8.2uM; PC3; HT_HG-U133A

VGLL3 HRG

3.20e-031971026666_UP
Diseaselower face morphology measurement

VGLL3 AXIN2

5.97e-04109102EFO_0010948
Diseaseage at menarche

VGLL3 BSX POU3F2

8.76e-04594103EFO_0004703
Diseasetransient cerebral ischemia (biomarker_via_orthology)

AXIN2 MECP2

1.23e-03157102DOID:224 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
APHAHHPLHKGDHHH

BSX

66

Q3C1V8
NHHHHHHHALHEAPK

BTBD11

331

A6QL63
TKHVHHHYIHHHAVP

AXIN2

511

Q9Y2T1
SSMAHHHHPLHPHHW

HEY2

171

Q9UBP5
HGSRDHHHPHKPHEH

HRG

281

P04196
PHKHHSHEQHPHGHH

HRG

351

P04196
STVSDKFPHHHHHHH

ONECUT1

116

Q9UBC0
STVSDKFHHPHPHHH

ONECUT2

161

O95948
PPKKEHHHHHHHSES

MECP2

361

P51608
HHHHHHHSESPKAPV

MECP2

366

P51608
SQSKSHHHHPPHHSP

POU4F2

121

Q12837
RDAHDEPHHADHHPH

POU3F2

216

P20265
HMHDVYMRHHHPHAH

VGLL3

221

A8MV65