Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

KIF21B TPR MYH3 SPIRE2 CTTNBP2 CEP290 MYO18A DAXX KATNAL1 PRC1 KRIT1 SMTN TUBGCP6 SPTBN4 KIF15 MICALL2 STARD9 SVIL CGN MACF1 CORO6 KIFC3 AGBL1 VCL

1.58e-08109911624GO:0008092
GeneOntologyMolecularFunctioncytoskeletal motor activity

KIF21B MYH3 DNAH2 MYO18A KIF15 STARD9 KIFC3 DNAH5 DNAH8

2.90e-081181169GO:0003774
GeneOntologyMolecularFunctionmicrotubule motor activity

KIF21B DNAH2 KIF15 STARD9 KIFC3 DNAH5 DNAH8

1.65e-07701167GO:0003777
GeneOntologyMolecularFunctiontubulin binding

KIF21B TPR SPIRE2 CEP290 KATNAL1 PRC1 KRIT1 TUBGCP6 KIF15 STARD9 CGN MACF1 KIFC3 AGBL1

1.94e-0742811614GO:0015631
GeneOntologyMolecularFunctionmicrotubule binding

KIF21B SPIRE2 CEP290 KATNAL1 PRC1 KRIT1 TUBGCP6 KIF15 STARD9 CGN MACF1 KIFC3

2.41e-0730811612GO:0008017
GeneOntologyMolecularFunctionATP-dependent activity

KIF21B MYD88 MYH3 ATP6V1E1 VPS72 DNAH2 MYO18A KATNAL1 KIF15 STARD9 ATAD2B MACF1 KIFC3 DNAH5 DNAH8 AQR

5.29e-0761411616GO:0140657
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH2 KIFC3 DNAH5 DNAH8

3.11e-06181164GO:0008569
GeneOntologyMolecularFunctionATP-dependent histone chaperone activity

MYD88 VPS72

3.35e-0521162GO:0140674
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

KIF21B MYH3 DNAH2 MYO18A KATNAL1 RGS12 ARF4 ARL1 KIF15 ATAD2B MACF1 SEPTIN10 DNAH5 DNAH8 AQR

4.29e-0577511615GO:0017111
GeneOntologyMolecularFunctionATP hydrolysis activity

KIF21B MYH3 DNAH2 MYO18A KATNAL1 KIF15 ATAD2B MACF1 DNAH5 DNAH8 AQR

5.28e-0544111611GO:0016887
GeneOntologyMolecularFunctionactin filament binding

MYH3 MYO18A SPTBN4 MICALL2 SVIL MACF1 CORO6 VCL

5.46e-052271168GO:0051015
GeneOntologyMolecularFunctionmicrotubule minus-end binding

CEP290 TUBGCP6 MACF1

8.26e-05151163GO:0051011
GeneOntologyMolecularFunctionphospholipase D activator activity

ARF4 ARL1

1.00e-0431162GO:1990583
GeneOntologyMolecularFunctionpyrophosphatase activity

KIF21B MYH3 DNAH2 MYO18A KATNAL1 RGS12 ARF4 ARL1 KIF15 ATAD2B MACF1 SEPTIN10 DNAH5 DNAH8 AQR

1.04e-0483911615GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

KIF21B MYH3 DNAH2 MYO18A KATNAL1 RGS12 ARF4 ARL1 KIF15 ATAD2B MACF1 SEPTIN10 DNAH5 DNAH8 AQR

1.06e-0484011615GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

KIF21B MYH3 DNAH2 MYO18A KATNAL1 RGS12 ARF4 ARL1 KIF15 ATAD2B MACF1 SEPTIN10 DNAH5 DNAH8 AQR

1.06e-0484011615GO:0016818
GeneOntologyMolecularFunctionactin binding

MYH3 SPIRE2 MYO18A SMTN SPTBN4 MICALL2 SVIL CGN MACF1 CORO6 VCL

1.10e-0447911611GO:0003779
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH2 DNAH5 DNAH8

5.63e-04281163GO:0051959
GeneOntologyMolecularFunctionphosphatidylinositol phosphate binding

NCF4 ASAP1 KRIT1 CADPS SVIL ZFYVE26

1.09e-031991166GO:1901981
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH2 DNAH5 DNAH8

1.29e-03371163GO:0045505
GeneOntologyMolecularFunctionphosphatidylinositol-4,5-bisphosphate binding

ASAP1 KRIT1 CADPS SVIL

2.29e-03951164GO:0005546
GeneOntologyMolecularFunctionphosphatidylinositol binding

NCF4 ASAP1 KRIT1 CADPS MTM1 SVIL ZFYVE26

2.49e-033161167GO:0035091
GeneOntologyBiologicalProcessmicrotubule-based process

KIF21B TPR SPIRE2 CFAP91 CEP290 RTTN DNAH2 CC2D1A KATNAL1 PRC1 TUBGCP6 CFAP54 KIF15 STARD9 CEP250 CGN MACF1 TUBA4B KIFC3 DNAH5 DNAH8 PCNT

1.49e-07105811922GO:0007017
GeneOntologyBiologicalProcessmicrotubule cytoskeleton organization

TPR SPIRE2 CFAP91 CEP290 RTTN DNAH2 CC2D1A KATNAL1 PRC1 TUBGCP6 KIF15 STARD9 CEP250 CGN TUBA4B DNAH5 DNAH8 PCNT

1.64e-0772011918GO:0000226
GeneOntologyBiologicalProcesscytokinesis

SPIRE2 DAXX PRC1 WNK1 PIK3R4 SVIL ZFYVE26 EXOC2 SEPTIN10 EXOC4

3.00e-0720411910GO:0000910
GeneOntologyBiologicalProcesscell cycle process

TPR SPIRE2 RTTN CC2D1A DAXX E2F5 PHF8 PRC1 WNK1 PIK3R4 TUBGCP6 DACT1 RINT1 KIF15 STARD9 CEP250 SVIL ANKRD17 TTI1 ZFYVE26 EXOC2 SEPTIN10 EXOC4 PCNT

2.08e-06144111924GO:0022402
GeneOntologyBiologicalProcessmitotic cell cycle

TPR NRDE2 DAXX E2F5 AZI2 PHF8 PRC1 WNK1 TUBGCP6 DACT1 RINT1 KIF15 CEP250 ANKRD17 ZFYVE26 TUBA4B EXOC2 EXOC4 PCNT

5.40e-06101411919GO:0000278
GeneOntologyBiologicalProcesscytoskeleton-dependent cytokinesis

SPIRE2 DAXX WNK1 ZFYVE26 EXOC2 SEPTIN10 EXOC4

8.99e-061271197GO:0061640
GeneOntologyBiologicalProcessorganelle assembly

TPR MYH3 CFAP91 CEP290 RTTN DNAH2 PRC1 WNK1 ASAP1 ARF4 TUBGCP6 CFAP54 KIF15 STARD9 CEP250 MTM1 DNAH5 DNAH8 PCNT

2.72e-05113811919GO:0070925
GeneOntologyBiologicalProcesscilium organization

CFAP91 CEP290 RTTN DNAH2 ASAP1 ARF4 CFAP54 CEP250 DNAH5 DNAH8 PCNT

9.89e-0547611911GO:0044782
GeneOntologyBiologicalProcessregulation of RNA export from nucleus

TPR NRDE2 WNK1

1.20e-04171193GO:0046831
GeneOntologyBiologicalProcessestablishment or maintenance of cell polarity

CEP290 MYO18A CCDC85C KRIT1 ARF4 AMOTL1 MACF1 EXOC4

1.24e-042571198GO:0007163
GeneOntologyBiologicalProcessGolgi vesicle transport

SPIRE2 MYO18A ASAP1 ARF4 ARL1 RINT1 MACF1 EXOC2 EXOC4

1.56e-043391199GO:0048193
GeneOntologyBiologicalProcessregulation of nucleobase-containing compound transport

TPR NRDE2 WNK1

1.99e-04201193GO:0032239
GeneOntologyBiologicalProcessmitotic cytokinesis

DAXX WNK1 ZFYVE26 EXOC2 EXOC4

2.25e-04951195GO:0000281
GeneOntologyBiologicalProcesscilium assembly

CFAP91 CEP290 DNAH2 ASAP1 ARF4 CFAP54 CEP250 DNAH5 DNAH8 PCNT

2.54e-0444411910GO:0060271
GeneOntologyBiologicalProcessregulation of cytokinesis

PRC1 WNK1 PIK3R4 SVIL ZFYVE26

2.73e-04991195GO:0032465
GeneOntologyBiologicalProcessendoplasmic reticulum tubular network formation

RTN4 RTN3

3.26e-0451192GO:0071787
GeneOntologyBiologicalProcessregulation of heterochromatin formation

TPR PHF8 BAZ1A

3.47e-04241193GO:0031445
GeneOntologyCellularComponentsupramolecular fiber

KIF21B MYH3 KRT81 DNAH2 MYO18A DAXX KATNAL1 PRC1 GFAP SMTN TUBGCP6 SPTBN4 KIF15 MTM1 SVIL MACF1 TUBA4B KIFC3 DNAH5 DNAH8 VCL PCNT

6.45e-07117911822GO:0099512
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

KIF21B KRT81 DNAH2 DAXX KATNAL1 PRC1 GFAP SMTN TUBGCP6 SPTBN4 KIF15 SVIL MACF1 TUBA4B KIFC3 DNAH5 DNAH8 VCL PCNT

6.65e-0789911819GO:0099513
GeneOntologyCellularComponentsupramolecular polymer

KIF21B MYH3 KRT81 DNAH2 MYO18A DAXX KATNAL1 PRC1 GFAP SMTN TUBGCP6 SPTBN4 KIF15 MTM1 SVIL MACF1 TUBA4B KIFC3 DNAH5 DNAH8 VCL PCNT

7.22e-07118711822GO:0099081
GeneOntologyCellularComponentmicrotubule

KIF21B DNAH2 DAXX KATNAL1 PRC1 TUBGCP6 KIF15 SVIL MACF1 TUBA4B KIFC3 DNAH5 DNAH8 PCNT

1.90e-0653311814GO:0005874
GeneOntologyCellularComponentmicrotubule associated complex

KIF21B TPR DNAH2 KATNAL1 KIF15 KIFC3 DNAH5 DNAH8

3.71e-061611188GO:0005875
GeneOntologyCellularComponentactin cytoskeleton

DENND2A MYH3 CTTNBP2 MYO18A ASAP1 SMTN SPTBN4 MICALL2 SVIL CGN MACF1 MYH16 VCL

2.28e-0557611813GO:0015629
GeneOntologyCellularComponentcell division site

SPIRE2 TUBGCP6 PLCD3 SVIL SEPTIN10

9.03e-05801185GO:0032153
GeneOntologyCellularComponentmicrotubule organizing center

CEP290 RTTN MYO18A CC2D1A KATNAL1 SMTN TUBGCP6 KIF15 STARD9 KIAA1217 CEP250 ZFYVE26 KIFC3 EXOC4 PCNT

2.08e-0491911815GO:0005815
GeneOntologyCellularComponentdynein complex

TPR DNAH2 DNAH5 DNAH8

2.45e-04541184GO:0030286
GeneOntologyCellularComponentmyosin complex

MYH3 MYO18A CGN MYH16

3.46e-04591184GO:0016459
GeneOntologyCellularComponentaxonemal dynein complex

DNAH2 DNAH5 DNAH8

3.68e-04251183GO:0005858
GeneOntologyCellularComponentspindle pole

KATNAL1 PRC1 TUBGCP6 KIF15 CEP250 NSMCE1

1.10e-032051186GO:0000922
GeneOntologyCellularComponentaxoneme

CFAP91 DNAH2 PIK3R4 CFAP54 DNAH5 DNAH8

1.15e-032071186GO:0005930
GeneOntologyCellularComponentciliary plasm

CFAP91 DNAH2 PIK3R4 CFAP54 DNAH5 DNAH8

1.18e-032081186GO:0097014
GeneOntologyCellularComponentcell cortex

SPIRE2 CTTNBP2 DAXX SPTBN4 MACF1 EXOC2 SEPTIN10 EXOC4

1.23e-033711188GO:0005938
GeneOntologyCellularComponentcentrosome

CEP290 RTTN CC2D1A KATNAL1 TUBGCP6 KIF15 KIAA1217 CEP250 ZFYVE26 KIFC3 EXOC4 PCNT

1.38e-0377011812GO:0005813
GeneOntologyCellularComponentpodosome

ASAP1 SVIL VCL

1.60e-03411183GO:0002102
GeneOntologyCellularComponentouter dynein arm

DNAH5 DNAH8

2.01e-03121182GO:0036157
GeneOntologyCellularComponentapical junction complex

CCDC85C MICALL2 AMOTL1 CGN KIFC3

2.04e-031581185GO:0043296
DomainDHC_N1

DNAH2 DNAH5 DNAH8

1.31e-0581173PF08385
DomainDynein_heavy_dom-1

DNAH2 DNAH5 DNAH8

1.31e-0581173IPR013594
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH5 DNAH8

8.29e-05141173IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH5 DNAH8

8.29e-05141173IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH5 DNAH8

8.29e-05141173IPR013602
DomainDHC_N2

DNAH2 DNAH5 DNAH8

8.29e-05141173PF08393
DomainMT

DNAH2 DNAH5 DNAH8

8.29e-05141173PF12777
DomainAAA_8

DNAH2 DNAH5 DNAH8

8.29e-05141173PF12780
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH5 DNAH8

8.29e-05141173IPR011704
DomainAAA_5

DNAH2 DNAH5 DNAH8

8.29e-05141173PF07728
DomainDHC_fam

DNAH2 DNAH5 DNAH8

1.03e-04151173IPR026983
DomainDynein_heavy_dom

DNAH2 DNAH5 DNAH8

1.03e-04151173IPR004273
DomainDynein_heavy

DNAH2 DNAH5 DNAH8

1.03e-04151173PF03028
DomainKINESIN_MOTOR_1

KIF21B KIF15 STARD9 KIFC3

1.64e-04441174PS00411
Domain-

KIF21B KIF15 STARD9 KIFC3

1.64e-044411743.40.850.10
DomainKinesin_motor_dom

KIF21B KIF15 STARD9 KIFC3

1.64e-04441174IPR001752
DomainKinesin

KIF21B KIF15 STARD9 KIFC3

1.64e-04441174PF00225
DomainKINESIN_MOTOR_2

KIF21B KIF15 STARD9 KIFC3

1.64e-04441174PS50067
DomainKISc

KIF21B KIF15 STARD9 KIFC3

1.64e-04441174SM00129
DomainMyosin_tail_1

MYH3 MYO18A CGN

1.83e-04181173PF01576
DomainMyosin_tail

MYH3 MYO18A CGN

1.83e-04181173IPR002928
DomainTRPM_tetra

TRPM3 TRPM1

2.32e-0441172IPR032415
DomainTRPM_tetra

TRPM3 TRPM1

2.32e-0441172PF16519
DomainP-loop_NTPase

KIF21B MYH3 DNAH2 MYO18A KATNAL1 ARF4 ARL1 KIF15 STARD9 ATAD2B KIFC3 SEPTIN10 DNAH5 DNAH8 AQR

2.66e-0484811715IPR027417
DomainRETICULON

RTN4 RTN3

3.84e-0451172PS50845
DomainSpectrin

TRIO SPTBN4 MACF1

3.87e-04231173PF00435
DomainCH

SMTN SPTBN4 MICALL2 MACF1

7.38e-04651174SM00033
DomainSpectrin_repeat

TRIO SPTBN4 MACF1

7.77e-04291173IPR002017
DomainReticulon

RTN4 RTN3

8.00e-0471172PF02453
DomainCH

SMTN SPTBN4 MICALL2 MACF1

9.75e-04701174PF00307
Domain-

SMTN SPTBN4 MICALL2 MACF1

1.03e-037111741.10.418.10
DomainSpectrin/alpha-actinin

TRIO SPTBN4 MACF1

1.04e-03321173IPR018159
DomainSPEC

TRIO SPTBN4 MACF1

1.04e-03321173SM00150
DomainReticulon

RTN4 RTN3

1.06e-0381172IPR003388
DomainCH

SMTN SPTBN4 MICALL2 MACF1

1.14e-03731174PS50021
DomainCH-domain

SMTN SPTBN4 MICALL2 MACF1

1.26e-03751174IPR001715
DomainAAA+_ATPase

DNAH2 KATNAL1 ATAD2B DNAH5 DNAH8

2.13e-031441175IPR003593
DomainAAA

DNAH2 KATNAL1 ATAD2B DNAH5 DNAH8

2.13e-031441175SM00382
DomainKinesin_motor_CS

KIF21B STARD9 KIFC3

2.15e-03411173IPR019821
DomainZnf_FYVE_PHD

SPIRE2 KDM5C PHF8 BAZ1A ZFYVE26

2.33e-031471175IPR011011
DomainKinesin-like_fam

KIF21B KIF15 KIFC3

2.46e-03431173IPR027640
DomainMyosin-like_IQ_dom

MYH3 MYO18A

6.21e-03191172IPR027401
Domain-

MYH3 MYO18A

6.21e-031911724.10.270.10
PathwayREACTOME_VXPX_CARGO_TARGETING_TO_CILIUM

ASAP1 ARF4 EXOC2 EXOC4

5.54e-0620854MM15208
PathwayREACTOME_VXPX_CARGO_TARGETING_TO_CILIUM

ASAP1 ARF4 EXOC2 EXOC4

6.81e-0621854M27479
PathwayREACTOME_CARGO_TRAFFICKING_TO_THE_PERICILIARY_MEMBRANE

ASAP1 ARF4 EXOC2 EXOC4

8.62e-0539854MM15209
PathwayREACTOME_CILIUM_ASSEMBLY

CEP290 ASAP1 ARF4 CEP250 EXOC2 EXOC4 PCNT

2.08e-04201857M27472
PathwayREACTOME_INTRA_GOLGI_AND_RETROGRADE_GOLGI_TO_ER_TRAFFIC

KIF21B ARF4 ARL1 RINT1 KIF15 GCC1 TUBA4B

2.21e-04203857M27654
PathwayREACTOME_CARGO_TRAFFICKING_TO_THE_PERICILIARY_MEMBRANE

ASAP1 ARF4 EXOC2 EXOC4

2.48e-0451854M27480
PathwayREACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES

CEP290 TUBGCP6 CEP250 TUBA4B PCNT

2.68e-0495855M6729
PathwayREACTOME_COPI_DEPENDENT_GOLGI_TO_ER_RETROGRADE_TRAFFIC

KIF21B ARF4 RINT1 KIF15 TUBA4B

3.40e-04100855M27650
PathwayREACTOME_ORGANELLE_BIOGENESIS_AND_MAINTENANCE

ESRRA CEP290 ASAP1 ARF4 CEP250 EXOC2 EXOC4 PCNT

4.17e-04297858M27050
PathwayWP_15Q11Q13_COPY_NUMBER_VARIATION

TRPM3 CGN TRPM1 NSMCE1

4.35e-0459854M48104
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH2 DNAH5 DNAH8

5.57e-0427853M47755
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

TRIO CEP290 CCDC85C CC2D1A AZI2 PHF8 RGS12 ASAP1 RINT1 PPP2R3A ALDH1A2 LUC7L2 KIAA1217 CEP250 MCU SVIL CGN ARHGAP29 FAM83G VCL EXOC4 PCNT

2.67e-138531222228718761
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DENND2A ATP6V1E1 CTTNBP2 HK1 TRIO RTN4 LARS1 MYO18A RTN3 HDHD2 GFAP ASAP1 ARF4 PIK3R4 SPTBN4 CADPS KIAA1217 MCU SVIL MACF1 CORO6 VCL EXOC4

9.32e-1014311222337142655
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SPIRE2 TRIO NELFB CCDC85C CC2D1A WNK1 RGS12 ARF4 PIK3R4 STARD9 KIAA1217 SVIL CGN FAM83G ANKRD17 MACF1 AQR EXOC4

1.38e-098611221836931259
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

VPS72 KDM5C ESRRA RTN3 DAXX UBN2 WNK1 ALDH1A2 KIF15 KIAA1217 MACF1 EXOC4 PCNT

1.65e-075881221338580884
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

NRDE2 ESRRA RTN4 MYO18A CC2D1A DAXX PYM1 PRC1 UBN2 ANKRD17 MACF1 CKAP4 VCL EXOC4

2.73e-077241221436232890
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

KIF21B TPR ATP6V1E1 HK1 LARS1 DNAH2 PRC1 WNK1 LUC7L2 KIAA1217 CEP250 ANKRD17 MACF1 SEPTIN10 PCNT

3.05e-078471221535235311
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

TPR HK1 LARS1 PNO1 PHF8 ASAP1 ARF4 SMTN PIK3R4 PLCD3 BAZ1A ANKRD17 MACF1 CKAP4 EXOC2 AQR VCL EXOC4

1.21e-0613531221829467282
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CTTNBP2 CEP290 NELFB UBN2 WNK1 GATAD2B PLCD3 TRPM3 CGN MACF1 EXOC4

1.42e-064931221115368895
Pubmed

Isolation of several human axonemal dynein heavy chain genes: genomic structure of the catalytic site, phylogenetic analysis and chromosomal assignment.

DNAH2 DNAH5 DNAH8

1.46e-06712239256245
Pubmed

Mutations in DNAH17, Encoding a Sperm-Specific Axonemal Outer Dynein Arm Heavy Chain, Cause Isolated Male Infertility Due to Asthenozoospermia.

DNAH2 DNAH5 DNAH8

1.46e-067122331178125
Pubmed

Prediction of the coding sequences of unidentified human genes. XV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

DENND2A CCPG1 ASAP1 KIAA1217 ATAD2B MACF1

1.78e-06103122610574462
Pubmed

An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.

MYD88 MAGEA8 KRT81 RTN4 SLC35C2 RTN3 GFAP KIAA1217 GCC1 KIFC3 VCL

2.12e-065141221129892012
Pubmed

Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.

CTTNBP2 GFAP KLHL11 CKAP4 EXOC2 EXOC4

2.62e-06110122627889896
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

TPR KDM5C LARS1 DAXX PRC1 GATAD2B ARF4 BAZ1A TTI1

2.80e-06332122932786267
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

NRDE2 RTN4 PIK3R4 PLCD3 KLHL11 ARL1 RINT1 LUC7L2 MCU ANKRD17 AQR EXOC4

3.29e-066501221238777146
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TPR KDM5C ESRRA NELFB MYO18A DAXX PHF8 GATAD2B SMTN TUBGCP6 SVIL ANKRD17 EXOC2

3.52e-067741221315302935
Pubmed

TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson's disease.

CEP290 DAXX GFAP SVIL TUBA4B

3.97e-0667122534644545
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

TPR RTN4 LARS1 CCDC85C CC2D1A PYM1 WNK1 ALDH1A2 BAZ1A KIAA1217 ANKRD17 MACF1 VCL PCNT

5.37e-069341221433916271
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

TPR CC2D1A KIAA1217 SVIL CGN MACF1 CKAP4 SEPTIN10 PCNT

5.39e-06360122933111431
Pubmed

A human MAP kinase interactome.

TPR CEP290 MYO18A DAXX WNK1 GFAP ASAP1 CEP250 ANKRD17 MACF1

8.84e-064861221020936779
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

TPR RTN4 LARS1 ARF4 CADPS SVIL TTI1 MACF1 CKAP4 AQR

1.09e-054981221036634849
Pubmed

The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.

TRIO LARS1 WNK1 GATAD2B ANKRD17 CKAP4 EXOC2 VCL

1.09e-05298122830737378
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

CFAP91 VPS72 AKAP17A TRIO CEP290 LARS1 GFAP KRIT1 PIK3R4 SPTBN4 CADPS MTM1 MACF1 KIFC3 EXOC4 PCNT

1.14e-0512851221635914814
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

TPR KDM5C NELFB CC2D1A PRC1 WNK1 GATAD2B MTM1 FAM83G EXOC4

1.19e-055031221016964243
Pubmed

Transient receptor potential melastatin 1 (TRPM1) is an ion-conducting plasma membrane channel inhibited by zinc ions.

TRPM3 TRPM1

1.22e-052122221278253
Pubmed

RTN3 and RTN4: Architects of SARS-CoV-2 replication organelles.

RTN4 RTN3

1.22e-052122237318453
Pubmed

Pro-apoptotic ASY/Nogo-B protein associates with ASYIP.

RTN4 RTN3

1.22e-052122212811824
Pubmed

Arf4 determines dentate gyrus-mediated pattern separation by regulating dendritic spine development.

ASAP1 ARF4

1.22e-052122223050017
Pubmed

The Arf GAP ASAP1 provides a platform to regulate Arf4- and Rab11-Rab8-mediated ciliary receptor targeting.

ASAP1 ARF4

1.22e-052122222983554
Pubmed

Reshaping of the endoplasmic reticulum limits the rate for nuclear envelope formation.

RTN4 RTN3

1.22e-052122218779370
Pubmed

Overexpression of Protein Phosphatase 2 Regulatory Subunit B"Alpha Promotes Glycolysis by Regulating Hexokinase 1 in Hepatocellular Carcinoma.

HK1 PPP2R3A

1.22e-052122235945177
Pubmed

HK1 haemolytic anaemia in association with a neurological phenotype and co-existing CEP290 Meckel-Gruber in a Romani family.

HK1 CEP290

1.22e-052122234532855
Pubmed

Reticulons promote formation of ER-derived double-membrane vesicles that facilitate SARS-CoV-2 replication.

RTN4 RTN3

1.22e-052122237093123
Pubmed

The Implication of Reticulons (RTNs) in Neurodegenerative Diseases: From Molecular Mechanisms to Potential Diagnostic and Therapeutic Approaches.

RTN4 RTN3

1.22e-052122233924890
Pubmed

RTN3 and RTN4: Candidate modulators in vascular cell apoptosis and atherosclerosis.

RTN4 RTN3

1.22e-052122220717916
Pubmed

Reticulon and CLIMP-63 regulate nanodomain organization of peripheral ER tubules.

RTN4 CKAP4

1.22e-052122231469817
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH2 DNAH5 DNAH8

1.49e-051412239373155
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

AKAP17A LARS1 MYO18A PNO1 PHF8 PRC1 PIK3R4 BAZ1A MACF1 CKAP4 AQR EXOC4

1.56e-057591221235915203
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

TRIO CEP290 CCDC85C PHF8 ASAP1 RINT1 PPP2R3A KIF15 MTM1 SVIL CGN TTI1 CKAP4 PCNT

1.97e-0510491221427880917
Pubmed

RBR-type E3 ubiquitin ligase RNF144A targets PARP1 for ubiquitin-dependent degradation and regulates PARP inhibitor sensitivity in breast cancer cells.

LARS1 MYO18A PLCD3 SVIL

2.29e-0547122429212245
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

TPR VPS72 CCDC85C CC2D1A PHF8 UBN2 AMOTL1 CGN VCL EXOC4

2.51e-055491221038280479
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

TPR AKAP17A LARS1 MYO18A DAXX PRC1 ARF4 SMTN PLCD3 LUC7L2 SVIL TUBA4B CKAP4

3.04e-059491221336574265
Pubmed

E-cadherin interactome complexity and robustness resolved by quantitative proteomics.

RTN4 CCDC85C CC2D1A ASAP1 KIAA1217 SVIL CGN ARHGAP29 MACF1 VCL

3.20e-055651221025468996
Pubmed

Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.

WNK1 RGS12 PIK3R4 LUC7L2 CEP250 SVIL CGN

3.43e-05255122715324660
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KIF21B TPR CTTNBP2 TRIO UBN2 GATAD2B SPTBN4 KIF15 KIAA1217 SVIL ANKRD17 MACF1 PCNT

3.53e-059631221328671696
Pubmed

Arl6IP1 has the ability to shape the mammalian ER membrane in a reticulon-like fashion.

RTN4 RTN3

3.65e-053122224262037
Pubmed

Interaction of calcium-dependent activator protein for secretion 1 (CAPS1) with the class II ADP-ribosylation factor small GTPases is required for dense-core vesicle trafficking in the trans-Golgi network.

ARF4 CADPS

3.65e-053122220921225
Pubmed

Mapping of interaction domains mediating binding between BACE1 and RTN/Nogo proteins.

RTN4 RTN3

3.65e-053122216979658
Pubmed

Negative elongation factor complex enables macrophage inflammatory responses by controlling anti-inflammatory gene expression.

MYD88 NELFB

3.65e-053122232385332
Pubmed

A phosphoinositide conversion mechanism for exit from endosomes.

MTM1 EXOC4

3.65e-053122226760201
Pubmed

The two-hydrophobic domain tertiary structure of reticulon proteins is critical for modulation of beta-secretase BACE1.

RTN4 RTN3

3.65e-053122219405102
Pubmed

Reticulon 3 mediates Bcl-2 accumulation in mitochondria in response to endoplasmic reticulum stress.

RTN4 RTN3

3.65e-053122217191123
Pubmed

Archvillin, a muscle-specific isoform of supervillin, is an early expressed component of the costameric membrane skeleton.

SVIL VCL

3.65e-053122212711699
Pubmed

Direct binding of CoREST1 to SUMO-2/3 contributes to gene-specific repression by the LSD1/CoREST1/HDAC complex.

TPR DAXX PHF8 GATAD2B BAZ1A

3.73e-05106122519394292
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

VPS72 AKAP17A KDM5C ESRRA PHF8 GATAD2B TUBGCP6 CADPS LUC7L2 ANKRD17 MACF1 CKAP4 AGBL1 NSMCE1

3.87e-0511161221431753913
Pubmed

The CP110-interacting proteins Talpid3 and Cep290 play overlapping and distinct roles in cilia assembly.

CEP290 CEP250 PCNT

3.92e-0519122324421332
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TPR HK1 TRIO RTN4 LARS1 RTN3 PRC1 ARF4 PIK3R4 BAZ1A STARD9 LUC7L2 CKAP4 DNAH5 AQR VCL

4.00e-0514251221630948266
Pubmed

Proteins recruited by SH3 domains of Ruk/CIN85 adaptor identified by LC-MS/MS.

PRC1 ASAP1 FAM83G CKAP4 SEPTIN10

4.09e-05108122519531213
Pubmed

The histone demethylase Jarid1b ensures faithful mouse development by protecting developmental genes from aberrant H3K4me3.

KDM5C GFAP VCL

4.60e-0520122323637629
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TPR TRIO RTN4 MYO18A RTN3 GFAP GATAD2B ASAP1 ARF4 CADPS KIAA1217 MACF1 CKAP4 SEPTIN10

4.82e-0511391221436417873
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

KIF21B RTTN MYO18A KIFC3 DNAH8 PCNT

5.38e-05187122626460568
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

TPR CCDC85C PRC1 ARF4 SMTN TUBGCP6 RINT1 MICALL2 SVIL KIFC3 AQR VCL NSMCE1 EXOC4

5.60e-0511551221420360068
Pubmed

Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.

RTN4 RTN3 CKAP4

6.18e-0522122337225996
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

CCPG1 HK1 RTN4 MYO18A RTN3 CC2D1A PYM1 TUBGCP6 ARL1 RINT1 MACF1 CKAP4 AQR VCL EXOC4 PCNT

6.61e-0514871221633957083
Pubmed

Type I interferon production enhances susceptibility to Listeria monocytogenes infection.

MYD88 BCL2L12

7.29e-054122215302901
Pubmed

IL-27 synthesis induced by TLR ligation critically depends on IFN regulatory factor 3.

MYD88 BCL2L12

7.29e-054122217548596
Pubmed

Astrocytes as a regulated source of retinoic acid for the brain.

GFAP ALDH1A2

7.29e-054122222930583
Pubmed

An aPKC-exocyst complex controls paxillin phosphorylation and migration through localised JNK1 activation.

EXOC2 EXOC4

7.29e-054122219885391
Pubmed

Tuberculosis toxin blocking phagosome maturation inhibits a novel Ca2+/calmodulin-PI3K hVPS34 cascade.

KRIT1 PIK3R4

7.29e-054122212925680
Pubmed

Association with PAK2 Enables Functional Interactions of Lentiviral Nef Proteins with the Exocyst Complex.

EXOC2 EXOC4

7.29e-054122226350970
Pubmed

REEP5 depletion causes sarco-endoplasmic reticulum vacuolization and cardiac functional defects.

RTN4 CKAP4

7.29e-054122232075961
Pubmed

Profound defects in pupillary responses to light in TRPM-channel null mice: a role for TRPM channels in non-image-forming photoreception.

TRPM3 TRPM1

7.29e-054122222211741
Pubmed

Orphan Nuclear Receptor ERRα Controls Macrophage Metabolic Signaling and A20 Expression to Negatively Regulate TLR-Induced Inflammation.

MYD88 ESRRA

7.29e-054122226200012
Pubmed

Analysis of a Set of KDM5C Regulatory Genes Mutated in Neurodevelopmental Disorders Identifies Temporal Coexpression Brain Signatures.

KDM5C PHF8

7.29e-054122234356104
Pubmed

Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid beta-protein.

RTN4 RTN3

7.29e-054122216965550
Pubmed

Salmonella-directed recruitment of new membrane to invasion foci via the host exocyst complex.

EXOC2 EXOC4

7.29e-054122220579884
Pubmed

Centrosomal proteins CG-NAP and kendrin provide microtubule nucleation sites by anchoring gamma-tubulin ring complex.

CEP290 TUBGCP6 CEP250 PCNT

8.78e-0566122412221128
Pubmed

Identification and classification of 16 new kinesin superfamily (KIF) proteins in mouse genome.

KIF15 STARD9 KIFC3

9.15e-052512239275178
Pubmed

Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.

KIF21B DENND2A MYO18A SVIL

9.31e-0567122429254152
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PHF8 ASAP1 CADPS STARD9 MACF1 PLXNA2 AQR PCNT

9.90e-05407122812693553
Pubmed

Intrinsically Disordered Protein TEX264 Mediates ER-phagy.

CCPG1 RTN4 RTN3 DAXX RINT1

1.02e-04131122531006538
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

CTTNBP2 TRIO CCDC85C PIK3R4 ANKRD17 PCNT

1.07e-04212122633853758
Pubmed

Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.

ESRRA DAXX SAT2 CEP250 MACF1

1.10e-04133122515604093
Pubmed

The MyD88 pathway in plasmacytoid and CD4+ dendritic cells primarily triggers type I IFN production against measles virus in a mouse infection model.

MYD88 BCL2L12

1.21e-045122224078691
Pubmed

The centriolar satellite protein Cep131 is important for genome stability.

CEP290 PCNT

1.21e-045122222797915
Pubmed

The Lyme disease spirochete Borrelia burgdorferi utilizes multiple ligands, including RNA, for interferon regulatory factor 3-dependent induction of type I interferon-responsive genes.

MYD88 BCL2L12

1.21e-045122220404081
Pubmed

Absence of TRIF signaling in lipopolysaccharide-stimulated murine mast cells.

MYD88 BCL2L12

1.21e-045122221441453
Pubmed

Src-dependent phosphorylation of ASAP1 regulates podosomes.

ASAP1 VCL

1.21e-045122217893324
Pubmed

Age-dependent ataxia and neurodegeneration caused by an αII spectrin mutation with impaired regulation of its calpain sensitivity.

GFAP SPTBN4

1.21e-045122233790315
Pubmed

Cooperation between MyD88 and TRIF pathways in TLR synergy via IRF5 activation.

MYD88 BCL2L12

1.21e-045122217275788
Pubmed

Dual signaling of MyD88 and TRIF is critical for maximal TLR4-induced dendritic cell maturation.

MYD88 BCL2L12

1.21e-045122218641322
Pubmed

Involvement of Exoc3l, a protein structurally related to the exocyst subunit Sec6, in insulin secretion.

EXOC2 EXOC4

1.21e-045122218480549
Pubmed

Reticulon family members modulate BACE1 activity and amyloid-beta peptide generation.

RTN4 RTN3

1.21e-045122215286784
Pubmed

Calcium-dependent activator protein for secretion 2 interacts with the class II ARF small GTPases and regulates dense-core vesicle trafficking.

ARF4 CADPS

1.21e-045122222111578
Pubmed

The humoral pattern recognition molecule PTX3 is a key component of innate immunity against urinary tract infection.

MYD88 BCL2L12

1.21e-045122224745336
Pubmed

Novel interactors and a role for supervillin in early cytokinesis.

STARD9 SVIL KIFC3

1.29e-0428122320309963
Pubmed

Proteomic identification of the MYST domain histone acetyltransferase TIP60 (HTATIP) as a co-activator of the myeloid transcription factor C/EBPalpha.

VPS72 GFAP MACF1

1.44e-0429122318239623
Pubmed

LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.

RTN4 DNAH2 MYO18A CKAP4 VCL

1.49e-04142122530809309
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

TRIO KDM5C DAXX AMOTL1 SVIL MACF1 DNAH5

1.78e-04332122737433992
Pubmed

Cutting edge: independent roles for IRF-3 and IRF-7 in hematopoietic and nonhematopoietic cells during host response to Chikungunya infection.

MYD88 BCL2L12

1.81e-046122222371392
InteractionNIN interactions

TRIO CEP290 CCDC85C CC2D1A RINT1 PPP2R3A KIAA1217 CEP250 MCU SVIL FAM83G SEPTIN10 EXOC4 PCNT

3.41e-0835912114int:NIN
InteractionYWHAG interactions

KIF21B SPIRE2 AKAP17A NELFB CCDC85C RTN3 PRC1 WNK1 RGS12 ARF4 PIK3R4 KIF15 BAZ1A STARD9 LUC7L2 CEP250 SVIL CGN ARHGAP29 FAM83G ANKRD17 MACF1 AQR VCL EXOC4

8.26e-08124812125int:YWHAG
InteractionYWHAH interactions

KIF21B SPIRE2 TRIO CEP290 NELFB CCDC85C CC2D1A WNK1 RGS12 PIK3R4 ARL1 STARD9 KIAA1217 MTM1 SVIL CGN FAM83G ANKRD17 MACF1 AQR VCL EXOC4 PCNT

1.44e-07110212123int:YWHAH
InteractionDISC1 interactions

TRIO CEP290 KATNAL1 GATAD2B PLCD3 SPTBN4 SVIL MACF1 GCC1 KIFC3 CKAP4 EXOC4 PCNT

1.88e-0642912113int:DISC1
InteractionPCM1 interactions

KRT81 CEP290 CCDC85C CC2D1A PRC1 RINT1 KIF15 KIAA1217 CEP250 MTM1 SEPTIN10 EXOC4 PCNT

2.14e-0643412113int:PCM1
InteractionKCTD13 interactions

DENND2A ATP6V1E1 CTTNBP2 HK1 TRIO RTN4 LARS1 MYO18A RTN3 HDHD2 GFAP ASAP1 ARF4 PIK3R4 SPTBN4 CADPS KIAA1217 MCU SVIL MACF1 CORO6 VCL EXOC4

8.08e-06139412123int:KCTD13
InteractionCALCOCO2 interactions

CCPG1 VPS72 AKAP17A TRIO RTN4 LARS1 MYO18A DAXX AZI2 GATAD2B ARF4 CHRDL1

3.66e-0548612112int:CALCOCO2
InteractionCEP135 interactions

CEP290 RTTN CC2D1A AZI2 DACT1 CEP250 CGN ARHGAP29 PCNT

3.94e-052721219int:CEP135
InteractionOFD1 interactions

KRT81 CEP290 LARS1 CCDC85C CC2D1A LUC7L2 KIFC3 SEPTIN10 EXOC4 PCNT

4.69e-0534712110int:OFD1
InteractionKRT19 interactions

KRT81 CEP290 GFAP KIF15 LUC7L2 AMOTL1 KIFC3 EXOC4 PCNT

5.21e-052821219int:KRT19
InteractionBICD2 interactions

TPR CCDC85C CC2D1A PRC1 ASAP1 PPP2R3A ALDH1A2 KIAA1217 SVIL DNAH5 VCL

5.26e-0542612111int:BICD2
InteractionSQSTM1 interactions

MYD88 CCPG1 TRIO RTN4 CEP290 CCDC85C RTN3 CC2D1A DAXX AZI2 PRC1 WNK1 ARF4 ARL1 LUC7L2 CEP250 AMOTL1 CKAP4 EXOC4 PCNT

5.73e-05125712120int:SQSTM1
InteractionINTS4P2 interactions

MYO18A GFAP CKAP4

5.78e-05131213int:INTS4P2
InteractionSSX2IP interactions

CEP290 CCDC85C DAXX RINT1 CEP250 ZFYVE26 KIFC3 SEPTIN10 PCNT

6.13e-052881219int:SSX2IP
InteractionMAPRE3 interactions

CTTNBP2 TRIO PIK3R4 KIF15 KIAA1217 MACF1 EXOC4 PCNT

7.58e-052301218int:MAPRE3
InteractionSYNE3 interactions

CCPG1 CCDC85C RTN3 CC2D1A RINT1 LUC7L2 KIAA1217 ARHGAP29 MACF1 CKAP4 PCNT

7.61e-0544412111int:SYNE3
InteractionH3C1 interactions

TPR CEP290 DNAH2 NELFB MYO18A DAXX PHF8 PRC1 UBN2 GATAD2B MICALL2 BAZ1A LUC7L2 CKAP4 DNAH8 AQR

9.80e-0590112116int:H3C1
InteractionYWHAZ interactions

SPIRE2 NELFB MYO18A CCDC85C WNK1 GFAP RGS12 ARL1 KIF15 STARD9 AMOTL1 SVIL CGN ARHGAP29 FAM83G ANKRD17 MACF1 EXOC2 VCL PCNT

1.11e-04131912120int:YWHAZ
InteractionNDC80 interactions

CEP290 CCDC85C KIF15 KIAA1217 CEP250 KIFC3 VCL EXOC4 PCNT

1.13e-043121219int:NDC80
InteractionYWHAB interactions

KIF21B SPIRE2 NELFB CCDC85C RTN3 WNK1 RGS12 ARF4 PIK3R4 DACT1 ARL1 STARD9 SVIL CGN FAM83G ANKRD17 MACF1

1.17e-04101412117int:YWHAB
InteractionGOLGA1 interactions

ARL1 ARHGAP29 MACF1 GCC1 KIFC3 EXOC4 PCNT

1.20e-041831217int:GOLGA1
InteractionYWHAE interactions

KIF21B SPIRE2 LARS1 NELFB CCDC85C PRC1 WNK1 RGS12 PIK3R4 ARL1 CEP250 AMOTL1 SVIL CGN FAM83G ANKRD17 MACF1 VCL EXOC4

1.73e-04125612119int:YWHAE
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF21B KIF15 STARD9 KIFC3

4.33e-0546774622
GeneFamilyDyneins, axonemal

DNAH2 DNAH5 DNAH8

4.84e-0517773536
GeneFamilyExocyst complex

EXOC2 EXOC4

6.32e-0497721055
GeneFamilyMyosin heavy chains

MYH3 MYH16

1.81e-03157721098
CoexpressionLAKE_ADULT_KIDNEY_C29_UNKNOWN_NOVEL_PT_CFH_POS_SUBPOPULATION_S2

CTTNBP2 ALDH1A2 SVIL ARHGAP29 MACF1 L3MBTL4

3.12e-06861226M39248
CoexpressionHALLMARK_MITOTIC_SPINDLE

TRIO PRC1 TUBGCP6 KIF15 CEP250 ARHGAP29 VCL PCNT

4.41e-061991228M5893
CoexpressionGRYDER_PAX3FOXO1_ENHANCERS_IN_TADS

ATP6V1E1 TRIO LRRC10B MYO18A PNO1 WNK1 KIAA1217 ATAD2B SVIL AP5M1 ARHGAP29 ANKRD17 TTI1 PLXNA2 AQR NSMCE1

1.86e-05100912216M157
CoexpressionGSE16385_MONOCYTE_VS_12H_ROSIGLITAZONE_IL4_TREATED_MACROPHAGE_UP

PNO1 E2F5 KRIT1 ARHGAP29 FAM83G SEPTIN10 EXOC4

4.33e-052001227M7898
CoexpressionGSE22432_CDC_VS_COMMON_DC_PROGENITOR_UP

CCPG1 RTN4 MYO18A ATAD2B CORO6 DNAH8 NSMCE1

4.33e-052001227M7831
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

TRIO E2F5 PHF8 KRIT1 PIK3R4 PPP2R3A BAZ1A ATAD2B ARHGAP29 ANKRD17 MACF1 AQR VCL PCNT

4.61e-0585612214M4500
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A CTTNBP2 TRIO PPP2R3A CFAP54 ALDH1A2 ARHGAP29 DNAH5

5.80e-081911228d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellCiliated_cells-B-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

MYH3 CFAP91 LRRC10B DNAH2 CFAP54 KIF15 TUBA4B

3.85e-0716612274b1056aad8a99827835242b8ab0c7f2bb84471f1
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

TRIO RTN4 ASAP1 BAZ1A SVIL MACF1 PLXNA2

1.02e-0619212278b86db2ebe0199fee0e9800566a619a24bfdeed5
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

TRIO TRPM3 SVIL ANKRD17 MACF1 L3MBTL4 EXOC4

1.02e-061921227e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_endoneurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

GOLGA6L4 KLHL11 DACT1 MICALL2 ATAD2B CORO6

3.00e-061451226e808502fa52baf1c400f3c9b918a167127e78af9
ToppCell10x5'-Lung-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|Lung / Manually curated celltypes from each tissue

PRC1 ACOX2 SMTN SLC51B KIF15 CKAP4

6.77e-06167122682739226347d74897be000f429b73543a031af96
ToppCell10x5'-Lung-Hematopoietic_progenitors|Lung / Manually curated celltypes from each tissue

PRC1 ACOX2 SMTN SLC51B KIF15 CKAP4

6.77e-061671226dec18caf0475002d4ad3c7bc7fc3050cbc8e6bae
ToppCellCiliated_cells-A-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CFAP91 LRRC10B C8orf74 TUBA4B DNAH5 ANKRD30BL

7.49e-0617012268b7ef1464ea589886b575ebad5447b085cbdcdba
ToppCellLPS-IL1RA-Epithelial_alveolar-Mes-Like-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH2 KIAA1217 DNAH5 DNAH8 EXOC4

9.56e-061031225eb9f008b5fb8a01df8ea4faf6e6aebc1a9db9bd3
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRC1 RGS12 KIF15 STARD9 KIFC3 SEPTIN10

1.01e-051791226327cc39161741ddbc4e8d45b9b3d30b3ce508929
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPIRE2 LRRC10B DNAH2 CFAP54 DNAH5 CCDC157

1.21e-05185122605bc89a566b0db90ae06506e067190a4739a0974
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.21e-051851226f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.21e-0518512263e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCiliated_cells-B-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.29e-0518712262b4262c2e7c7830a976be168cee6eeb738d4feda
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.29e-0518712269e10ed56090d82589bc457788282f664b70ace4b
ToppCellnormal_Lung-Myeloid_cells-pDCs|normal_Lung / Location, Cell class and cell subclass

PHF8 GATAD2B CENPBD1P RINT1 ATAD2B KIFC3

1.29e-051871226d36751372fd40a46441f07735c9c3c5dcb503f24
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated-Ciliated_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP91 LRRC10B DNAH2 ACOX2 CFAP54 DNAH5

1.37e-051891226b55de812043b670cbde810d7d42f45909b6d66ef
ToppCellCOVID-19-lung-Ciliated|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.37e-051891226a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCellPND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP91 LRRC10B DNAH2 ACOX2 CFAP54 DNAH5

1.37e-0518912264e83e49d1265ffe507fdb72924c77c4d1c73f0bd
ToppCellCiliated|World / shred by cell class for parenchyma

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.37e-051891226711181ca3b9102fb155168b646b0a9b09ff215b2
ToppCellCiliated_cells-B|World / lung cells shred on cell class, cell subclass, sample id

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.41e-0519012267031fbedc13be1a00f6333ad6d51849c3739c2e6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A TRIO PPP2R3A SVIL ARHGAP29 DNAH5

1.45e-0519112269032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A TRIO PPP2R3A SVIL ARHGAP29 DNAH5

1.45e-0519112265717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellnormal_Lung-Epithelial_cells-Ciliated|normal_Lung / Location, Cell class and cell subclass

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.50e-051921226097a13121820ab4e5cd2365600efccf5ea4ce8c3
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RTN4 RTN3 NCF4 ASAP1 BAZ1A CKAP4

1.54e-051931226e1855cff9a6bcfda9188b9fdf6c9d698405da990
ToppCellCOVID-19-Epithelial-Ciliated_cells|COVID-19 / Condition, Lineage and Cell class

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.59e-05194122643be5fbd51dd58839cb03ca3ddd05a458e1ddb74
ToppCellproximal-Epithelial-Ciliated|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.83e-0519912269700f06e51ddca85e482b4f9bd4a79bfcd3cfb76
ToppCellproximal-3-Epithelial-Ciliated|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.83e-0519912261188afad6fd5f01f9aeba225f611f38b237dd2c9
ToppCellproximal-Epithelial-Ciliated-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.83e-0519912262e8ace105c4e2405baa06d953e52888b54e2d055
ToppCellBiopsy_Control_(H.)-Epithelial-Ciliated|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.89e-0520012269ae434c78e08adf95da49c85616e3ca72d1227bf
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.89e-05200122652aef65f01b06cd98056f17977efe525aee6eb6f
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.89e-05200122655c148238d5c80c1faa3428a917ae8075be2c145
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.89e-05200122631d75c26055177d656df1fbb10b764cebd61e122
ToppCellBiopsy_Other_PF-Epithelial-Ciliated|Biopsy_Other_PF / Sample group, Lineage and Cell type

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.89e-052001226721371698bce8890853fb6b6b01a2c20293b39e9
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.89e-05200122685c98da55f7cd4ffdf9d309b56c8cc5d43f3c04c
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.89e-052001226bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.89e-052001226e1dce91c6c531bb212002a14705e496d77ad3490
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Unfolded_protein_responsible_cell|5w / Sample Type, Dataset, Time_group, and Cell type.

ATP6V1E1 CCPG1 PNO1 ARF4 ARL1 RINT1

1.89e-052001226fa6a0f859fbf2d97d5849107290d578a44a88d7e
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_ciliated-Ciliated|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.89e-05200122612bc7d95c4166d12487081a76d210b7abe5991b0
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.89e-052001226ddd39b754bfaa98249d497dfb7e97ec58617a11a
ToppCellSigmoid-(1)_T_cell-(18)_cycling_gd_T|Sigmoid / shred on region, Cell_type, and subtype

MYO18A PRC1 SMTN TUBGCP6 KIF15 ZFYVE26

1.89e-0520012266e367abd1a4b87e20eb9095b8337723163e8bbae
ToppCellParenchyma_Control_(B.)-Epithelial-TX-Ciliated|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.89e-052001226a521cf837cadf280505ff9d7e641a205af7d6513
ToppCell10x_3'_v3-bone_marrow_(10x_3'_v3)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CCPG1 RTN3 NCF4 BAZ1A SVIL CKAP4

1.89e-052001226808571d74bb5c4d765ff13fc9393f88020d4e90d
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B DNAH5

1.89e-052001226918b576fd9491d23c2bb9d663fa5fb3505cb1c7e
ToppCellSigmoid-T_cell-cycling_gd_T|Sigmoid / Region, Cell class and subclass

MYO18A PRC1 SMTN TUBGCP6 KIF15 ZFYVE26

1.89e-0520012269769185abae084ffac36420c749625e679b70ca8
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high|E18.5-samps / Age Group, Lineage, Cell class and subclass

CC2D1A KATNAL1 RGS12 ALDH1A2 CHRDL1

6.61e-051541225212c340a096a3a9669d1aebd61c045cf1402a868
ToppCell10x5'-bone_marrow-Lymphocytic_B-GC_B_(I)|bone_marrow / Manually curated celltypes from each tissue

DENND2A PRC1 KIF15 C11orf91 TRPM1

7.24e-051571225d4da4057917dda066da0f2aac2621fdaf1fb943b
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCF4 PRC1 KIF15 CKAP4 VCL

8.90e-0516412252a230ea066decb798a0e6f2b96c7608c8e608031
ToppCellfacs-Marrow-T-cells-24m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NCF4 PRC1 KIF15 CKAP4 VCL

8.90e-051641225d02d39edd0bfef5a53b814ec6d5f026d41253218
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

KIF21B KATNAL1 CENPBD1P CYP4F22 KIFC3

9.96e-0516812253fb79aaa858057c82645a90bd139fc4f096323c7
ToppCellfacs-Lung-EPCAM-3m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC10B ACOX2 ALDH1A2 FAM83G DNAH5

1.05e-04170122582ccba6ec53f6ca0d19949a1277434c565af2983
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC10B ACOX2 ALDH1A2 FAM83G DNAH5

1.05e-041701225ab19ea729ed8c8361c870e79893d1a95a1e487fa
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RTTN PRC1 DACT1 TRPM3 CORO6

1.27e-0417712253e149bff1f1b393a7abe98984e37981c8296f95d
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP91 LRRC10B ACOX2 CFAP54 DNAH5

1.27e-0417712253cfde67b93f3986312f5e74e42504214d966e7dc
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCDHB4 SMTN DACT1 STARD9 SVIL

1.27e-041771225e65c0568dc5852108e9802273499bc7cf88fafab
ToppCellfacs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFAP91 LRRC10B ACOX2 CFAP54 DNAH5

1.27e-04177122512a52a12a87a31e501ced611f46a90d172ca7e35
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Zbtb32+_B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCF4 MCU FAM83G CYP4F22 LY86

1.27e-041771225a58c93be9767e3fe8fbb6b0db1210d3a33aac662
ToppCellCiliated_cells-B-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B

1.27e-041771225c38138fb5ad9766c2d240811210c854338cd612e
ToppCelldroplet-Lung-1m-Hematologic-lymphocytic-Zbtb32+_B_cell-Zbtb32+_B_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NCF4 MCU FAM83G CYP4F22 LY86

1.27e-0417712253ed383e5c0b15d9d5e75b98cf6d10609f48fc422
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CFAP91 LRRC10B CFAP54 TUBA4B DNAH5

1.31e-041781225de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CTTNBP2 PPP2R3A CFAP54 ALDH1A2 ARHGAP29

1.31e-041781225544379f5a6145429762258d426b876bb36c112f5
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SPIRE2 UBN2 KIAA1217 AGBL1 ANKRD30BL

1.34e-041791225815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

CFAP91 LRRC10B CFAP54 TUBA4B DNAH5

1.38e-041801225bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFAP91 LRRC10B DNAH2 CFAP54 DNAH5

1.38e-04180122592fb01b91261b3103454924cde56add337b41844
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DENND2A SMTN TRPM3 KIAA1217 SVIL

1.41e-041811225af92b8b7f455210dab502ef6964f3a0162180759
ToppCell10x5'-bone_marrow-Hematopoietic_progenitors-Cycling_pre-Myeloid-1|bone_marrow / Manually curated celltypes from each tissue

DNAH2 PRC1 SMTN KIF15 CKAP4

1.41e-041811225ccd0ed30cea3fb41d34f28b3e8d80a94493bef3c
ToppCellControl-Epithelial_cells-Airway_club|Control / group, cell type (main and fine annotations)

KIAA1217 MCU SVIL DNAH5 L3MBTL4

1.41e-041811225c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SMTN SVIL CHRDL1 PLXNA2 VCL

1.45e-04182122537547b36264090b49a193a8ef3a8d88e647f0b79
ToppCellCiliated_cells-B-SSc-ILD_02|World / lung cells shred on cell class, cell subclass, sample id

CFAP91 LRRC10B DNAH2 TUBA4B DNAH5

1.45e-041821225e44c4810dc7d51a76b86d7623f8e4c4d8b4bf2fc
ToppCellCiliated_cells-B-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B

1.56e-0418512254fc7113d3dadc716ec5a8e62b58543cc00ce5b16
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP91 LRRC10B DNAH2 CFAP54 DNAH5

1.56e-0418512255e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellCiliated_cells-A-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

CFAP91 LRRC10B CFAP54 TUBA4B DNAH5

1.56e-041851225d77ca57b02125a3a57a37f4aed20c89803b7d551
ToppCellCiliated_cells-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B

1.60e-041861225f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KIAA1217 MCU DNAH5 AGBL1 ANKRD30BL

1.60e-0418612252ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CFAP91 LRRC10B DNAH2 CFAP54 DNAH5

1.60e-04186122576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCell3'_v3-lymph-node_spleen-Hematopoietic_progenitors-Cycling_pre-Myeloid-2|lymph-node_spleen / Manually curated celltypes from each tissue

ATP6V1E1 KDM5C PRC1 SMTN ZFYVE26

1.64e-0418712253c10b8501226c69d71bcd99dc1c064a3c2154f87
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

CFAP91 LRRC10B CFAP54 TUBA4B DNAH5

1.64e-041871225f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellnormal_Lung-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

PHF8 GATAD2B CENPBD1P RINT1 KIFC3

1.64e-041871225a3592f056e1c2f82ba325fea2ecc4dd6c6347c81
ToppCellCiliated_cells-B-HP_01|World / lung cells shred on cell class, cell subclass, sample id

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B

1.64e-041871225bc1f33f332ac939c2425f510173430ca2ba0c3ee
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CCDC85C CGN ARHGAP29 KIFC3 PLXNA2

1.69e-04188122543a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CTTNBP2 TRIO CFAP54 ALDH1A2 ARHGAP29

1.69e-04188122563a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

CFAP91 LRRC10B DNAH2 TUBA4B DNAH5

1.69e-041881225606907c865bd2f11bb6474932716550f7723d858
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTTNBP2 LRRC10B UBN2 SPTBN4 CADPS

1.69e-041881225a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell(7)_Epithelial-F_(Ciliated)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

CFAP91 LRRC10B DNAH2 TUBA4B DNAH5

1.69e-0418812259a8b9f745eed9f129b6c582f48fbbaaacbebb4b3
ToppCellControl-Epithelial-Ciliated|Control / Disease state, Lineage and Cell class

CFAP91 LRRC10B CFAP54 TUBA4B DNAH5

1.73e-041891225c007fccd08728db3ea99af9da91d67b9b16dabb3
ToppCellPND01-Epithelial-Epithelial_Airway|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CFAP91 LRRC10B CFAP54 ALDH1A2 DNAH5

1.73e-04189122538cde34295566a4ecaf7d0a81c5a192cf17d0459
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

ASAP1 TRPM3 MCU ARHGAP29 PLXNA2

1.73e-04189122575c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRA-10._Endothelium_II|RA / Chamber and Cluster_Paper

ASAP1 TRPM3 MCU ARHGAP29 PLXNA2

1.73e-041891225c81787a8c662db5d7814c583dd64562857629e81
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A ALDH1A2 KIAA1217 ANKRD17 EXOC4

1.73e-041891225830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A TRIO SVIL DNAH5 VCL

1.73e-0418912258c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DENND2A TRIO SVIL DNAH5 VCL

1.73e-0418912255d902a4660a27548764bf04c6de152b565da835c
ToppCellCOVID-19-lung-Ciliated|lung / Disease (COVID-19 only), tissue and cell type

CFAP91 DNAH2 CFAP54 TUBA4B DNAH5

1.73e-04189122527329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPIRE2 CFAP91 LRRC10B ACOX2 DNAH5

1.77e-0419012259ffd18ef358f8e32c610ab6420f479067c8ba44b
ToppCellNasal_Brush-Epithelial-Ciliated_2|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP91 LRRC10B CFAP54 TUBA4B DNAH5

1.77e-0419012259ce7df056bfb24d70db4c3c4a2c57d89115de877
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|343B / Donor, Lineage, Cell class and subclass (all cells)

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B

1.77e-041901225169e600e95878000acf5d11f813f9028c7249646
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|343B / Donor, Lineage, Cell class and subclass (all cells)

CFAP91 LRRC10B DNAH2 CFAP54 TUBA4B

1.77e-0419012250cc36117c793d83cf4a1f66f47758a07d6712bd3
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-lung_ciliated_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SPIRE2 CFAP91 LRRC10B ACOX2 DNAH5

1.77e-0419012253ef39d61c98de4e5df946b995847aa65eba6a4b6
ToppCellPND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRIO ARF4 DACT1 ALDH1A2 CKAP4

1.77e-041901225947807863a9b247c301c6cf63d6fd5a2c8018e66
ToppCellfacs-Lung-nan-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPIRE2 LRRC10B ACOX2 TRPM3 DNAH5

1.77e-041901225e243b5fbb17b9ec3cc90bbe970c1d30b0fd1c2e1
ToppCellNasal_Brush-Epithelial-Ciliated_2|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CFAP91 LRRC10B CFAP54 TUBA4B DNAH5

1.77e-041901225833481ace2800354712e2ce709d5cdfd0aed3d42
DiseaseStrabismus

CADPS KIAA1217 EXOC2 DNAH5

4.99e-06291164HP_0000486
Diseasebrain measurement, neuroimaging measurement

KIF21B CTTNBP2 GATAD2B DACT1 ALDH1A2 CADPS MACF1 CORO6 AGBL1 EXOC4

6.51e-0555011610EFO_0004346, EFO_0004464
Diseaseneuroimaging measurement

KIF21B SPIRE2 CTTNBP2 GFAP GATAD2B DACT1 ALDH1A2 BAZ1A CADPS MACF1 EXOC2 AGBL1 PLXNA2 EXOC4

8.04e-05106911614EFO_0004346
Diseasehereditary spastic paraplegia 12 (implicated_via_orthology)

RTN4 RTN3

9.15e-0541162DOID:0110765 (implicated_via_orthology)
Diseaseresponse to bevacizumab, Proteinuria

TRIO DNAH5

1.52e-0451162EFO_0005943, HP_0000093
DiseaseFuchs' endothelial dystrophy (is_implicated_in)

LOXHD1 AGBL1

2.27e-0461162DOID:11555 (is_implicated_in)
DiseaseMASA syndrome (implicated_via_orthology)

TRPM3 TRPM1

3.18e-0471162DOID:0060246 (implicated_via_orthology)
Diseasevisceral heterotaxy (implicated_via_orthology)

CEP290 CC2D1A DNAH5

4.17e-04371163DOID:0050545 (implicated_via_orthology)
Diseaseosteoarthritis, hand

CFAP54 ALDH1A2 DNAH8

4.17e-04371163EFO_1000789
Diseasechemotherapy-induced alopecia, methylcobalamin deficiency type cblE

TRIO DNAH5

4.22e-0481162EFO_0005400, MONDO_0009354
Diseasecortical thickness

SPIRE2 CTTNBP2 VPS72 GATAD2B DACT1 ALDH1A2 BAZ1A CADPS MACF1 EXOC2 AGBL1 PLXNA2 EXOC4

4.41e-04111311613EFO_0004840
Diseasecholesteryl ester 20:5 measurement

CADPS SVIL CKAP4

6.97e-04441163EFO_0010349
Diseasesuntan

SPIRE2 CENPBD1P KIAA1217 EXOC2

7.43e-041031164EFO_0004279
Diseasediet measurement

CTTNBP2 VPS72 TRIO RTN4 GATAD2B SMTN CADPS KIAA1217 DNAH5 AGBL1 L3MBTL4 EXOC4

8.85e-04104911612EFO_0008111
Diseasesitting height ratio

HDHD2 ATAD2B EXOC2

1.07e-03511163EFO_0007118
Diseaselevel of Sphingomyelin (d34:2) in blood serum

ALDH1A2 ANKRD17

1.16e-03131162OBA_2045174
Diseaseimmature platelet measurement

RTTN ASAP1 TRPM3 SVIL

1.27e-031191164EFO_0803541
Diseasefree cholesterol to total lipids in very large VLDL percentage

BCAT2 RGS12 ALDH1A2

1.64e-03591163EFO_0022289
Diseasecholesterol to total lipids in IDL percentage

BCAT2 ALDH1A2 MACF1

1.72e-03601163EFO_0022233
Diseasebitter alcoholic beverage consumption measurement

DNAH2 MICALL2 AGBL1 PLXNA2

1.91e-031331164EFO_0010092
Diseasetriglycerides to total lipids in medium VLDL percentage

BCAT2 RGS12 ALDH1A2

1.98e-03631163EFO_0022335
Diseaselevel of Sphingomyelin (d34:1) in blood serum

ALDH1A2 ANKRD17

2.25e-03181162OBA_2045175
Diseasecholesterol to total lipids in very small VLDL percentage

BCAT2 RGS12 ALDH1A2

2.36e-03671163EFO_0022245
Diseasehydrocephalus (implicated_via_orthology)

CCDC85C E2F5

2.51e-03191162DOID:10908 (implicated_via_orthology)
Diseaseselenium measurement, response to dietary selenium supplementation

TRIO DNAH5

2.78e-03201162EFO_0006331, EFO_0600021
Diseaseplatelet component distribution width

DENND2A RTTN WNK1 ASAP1 TRPM3 ATAD2B SVIL MACF1 TUBA4B

3.00e-037551169EFO_0007984
Diseaseleucine measurement

BCAT2 PPP2R3A ALDH1A2

3.01e-03731163EFO_0009770
Diseaseworry measurement

CTTNBP2 RGS12 PPP2R3A GCC1

3.25e-031541164EFO_0009589
DiseaseFEV/FEC ratio

CTTNBP2 CCDC85C ASAP1 SMTN SLC51B KIF15 CADPS SVIL CHRDL1 EXOC2 DNAH5 LY86

3.29e-03122811612EFO_0004713
DiseasePrimary microcephaly

RTTN TUBGCP6

3.36e-03221162C0431350
Diseaseosteoarthritis, knee

SPIRE2 VPS72 ALDH1A2 KIAA1217

3.56e-031581164EFO_0004616

Protein segments in the cluster

PeptideGeneStartEntry
LTVDKLEEALLEARL

ACCSL

301

Q4AC99
IRFLEEKLIARFEEE

AZI2

66

Q9H6S1
DLLRLIRKDAILLTD

ACOX2

611

Q99424
LEARILKIEVLIDLR

CFAP54

2111

Q96N23
DVLLLKEALRLEREN

C8orf74

181

Q6P047
LDDLRNDLDRLFVKV

CKAP4

581

Q07065
LDKLADLVERDRAVL

ALDH1A2

106

O94788
KEAILRRLVALLEEE

BCL2L12

206

Q9HB09
LLELVREKEERILAL

AMOTL1

666

Q8IY63
VLARRIELLEEVKRL

AQR

901

O60306
LEEEELRKAILVVFA

ARL1

111

P40616
ASILLEELDLEKLRE

ANKRD17

1456

O75179
ELEELKERERLLVAF

CCDC157

531

Q569K6
EIRRLQEKELDLSEL

DAXX

201

Q9UER7
AEKQLELRLRDFLLD

BAZ1A

971

Q9NRL2
ELRLRDFLLDIEDRI

BAZ1A

976

Q9NRL2
LELEALDVTLILARK

AGBL1

96

Q96MI9
IRLEVLKELLRKREE

CFAP91

291

Q7Z4T9
KERFEEIKERLRVLL

CADPS

776

Q9ULU8
RELIERLEDLKEQLA

MCU

201

Q8NE86
ALDEKVAELVRFLLR

MAGEA8

111

P43361
QEVDILDLKETLRLR

KIF15

1036

Q9NS87
GIILREDIKELFLDL

LY86

71

O95711
LLERLRKLEFDISED

HDHD2

56

Q9H0R4
VDRERLKKLLDLLVD

ATAD2B

1396

Q9ULI0
CLRKLLRKLEELEEL

KCNG4

161

Q8TDN1
FLETLELGELRKVRL

LOXHD1

2001

Q8IVV2
NLELKELVLLLDEER

CCDC85C

141

A6NKD9
LDALELRGVELEKRL

MICALL2

751

Q8IY33
VCKLLRLDDLFILVE

PLXNA2

136

O75051
RIEALRELLLDKLLE

EXOC2

331

Q96KP1
RRAVEELLECLDLEK

MYO18A

1146

Q92614
LLELESREKLEAFLR

DNAH8

2361

Q96JB1
ERLIKKREELFLLQE

KIF21B

941

O75037
EKELRVRLPLEELEL

NRDE2

1146

Q9H7Z3
FDELRDKLLERVSAI

NELFB

66

Q8WX92
LLKDLLELTRREFQR

NCF4

266

Q15080
ELLTKLGRDDVLLEL

MYD88

91

Q99836
LRELRILALDFNKLE

LRRC10B

66

A6NIK2
LFLRRDVRLPLEVEK

KRIT1

506

O00522
KEDIDLDNLFRVLVL

L3MBTL4

471

Q8NA19
LERERLLEEVEKLLE

GOLGA6L4

346

A6NEF3
LLERERLLEEVEKLL

GOLGA6L4

371

A6NEF3
RLESARLRFLLEDEK

TUBGCP6

786

Q96RT7
FLKALLFELRLLDDD

AP5M1

51

Q9H0R1
IKQLRDELRLEEARL

GATAD2B

166

Q8WXI9
DELRLEEARLVLLKK

GATAD2B

171

Q8WXI9
KLARRRALEEELEDL

PYM1

186

Q9BRP8
VEDALALIRLDDLFL

PNO1

146

Q9NRX1
LARLDLERKIESLEE

GFAP

181

P14136
LERKIESLEEEIRFL

GFAP

186

P14136
LLRDAIKRREEFDLD

HK1

636

P19367
HKIEEEDRALLLRIL

PPP2R3A

581

Q06190
RALLRRESEVLDLKE

PCNT

1646

O95613
RAEEREIKFLDVLEL

MACF1

5991

Q9UPN3
GDLLLREKLDREELC

PCDHB4

81

Q9Y5E5
FKEVIHIRLEELLRV

ARHGAP29

71

Q52LW3
RLLLELLELLFDKFN

EXOC4

336

Q96A65
ILRERLTELERKLTF

CCPG1

426

Q9ULG6
QLDFRDRTLKLEEEL

GCC1

571

Q96CN9
VLELADRFLLIRLKE

KLHL11

176

Q9NVR0
RSRLEEKFLEENILL

DACT1

96

Q9NYF0
VIDRLRYLKAEIEDL

E2F5

126

Q15329
RTELEDLVKVLYLER

CHRDL1

436

Q9BU40
SLLLERRVIFIADKL

DENND2A

761

Q9ULE3
FLSRELIEKERDLER

CEP290

611

O15078
DLVIEALRARRKEVF

CTTNBP2

56

Q8WZ74
LLKEIILVDDLSDRV

GALNT4

166

Q8N4A0
LEEDLEQIKLSLRER

CEP250

1681

Q9BV73
LAFDQERLERKILAL

CC2D1A

851

Q6P1N0
ELLEAIKSRDLLALI

ASAP1

566

Q9ULH1
LETLLEEIKALRERV

CORO6

436

Q6QEF8
KLELLECIRRLIEVD

BCAT2

141

O15382
RKLKELEDEILRLLN

DNAH2

3546

Q9P225
DILRLIRELAEFEKL

SAT2

16

Q96F10
LQALRLEREEYVLLK

ESRRA

316

P11474
KTLDFIDVLLLARDE

CYP4F22

301

Q6NT55
LDLFRKALELIIDSE

NSMCE1

106

Q8WV22
KDLELLLDRVNDLIE

DNAH5

811

Q8TE73
VELELKERDVLSVFL

SLC51B

106

Q86UW2
ILPDEIFRLVKIRFL

PCDH11Y

146

Q9BZA8
LGFIEIREKLEELKR

LUC7L2

216

Q9Y383
RDFLSELELKRILET

FAM83G

56

A6ND36
ALKLIIRLFLVEDLV

RTN3

941

O95197
IRLFLVEDLVDSLKL

RTN3

946

O95197
LRRLFLVDDLVDSLK

RTN4

1106

Q9NQC3
LRLDDRRELVIKLET

RTTN

816

Q86VV8
RAELLKINLREVELD

KATNAL1

386

Q9BW62
LESDLKLDRLETFLR

SVIL

1261

O95425
RILDLQLEFDEKAVL

LARS1

1006

Q9P2J5
RLAEVELRLKDCLAE

KIFC3

211

Q9BVG8
VRKALQLEVDRLEEL

PRC1

271

O43663
AILRIEVEAVRFLKE

KIAA1217

781

Q5T5P2
EFLKLRRDLEEATLQ

MYH3

1171

P11055
LKLIRELREEIERLK

STARD9

396

Q9P2P6
ELREEIERLKALLLS

STARD9

401

Q9P2P6
KEFIDLLLDRIRKLA

TUBA4B

51

Q9H853
LLAIRKRSEEIVEFL

ANKRD30BL

176

A7E2S9
ERELRERLLSILLSK

AKAP17A

431

Q02040
LLVDELRDAVLLLFA

ARF4

111

P18085
AITLDLKLEVLRRFE

CENPBD1P

21

B2RD01
LKDLLETRELLEEVL

CGN

466

Q9P2M7
LCELEIRIKELELLT

C11orf91

141

Q3C1V1
FLSADERILVIRKDL

PIK3R4

336

Q99570
LEKRIEDLRVAAKLF

UBN2

456

Q6ZU65
ILESRDLRLEKRTLF

RGS12

1021

O14924
DLRLEKRTLFRLDLV

RGS12

1026

O14924
LALRDEYIKRLEELQ

MTM1

561

Q13496
LELQKDLVDDFRIRL

RINT1

506

Q6NUQ1
ILEILRFIRREKEIA

TPR

1196

P12270
AEIEEFLRRLLKRPE

PLCD3

241

Q8N3E9
FLRRLLKRPELEEIF

PLCD3

246

Q8N3E9
ELKLRLRLVEEEANI

SOGA3

586

Q5TF21
LELRAFLARVREAKE

SPIRE2

201

Q8WWL2
LDALVLDRVDFVKLL

TRPM3

516

Q9HCF6
DLLLTFDEAEVRKII

VCL

121

P18206
FKLEELRAALVLVVL

SLC35C2

131

Q9NQQ7
ALRAELIRQEKLELL

SPTBN4

416

Q9H254
LEEKRRLLEEEIIAF

SEPTIN10

406

Q9P0V9
EAELLKLRRELEEAA

MYH16

331

Q9H6N6
LDALVLDRVDFVKLL

TRPM1

466

Q7Z4N2
IKDLAREIRLVEDIF

PHF8

466

Q9UPP1
LKVLRARDDLITDLL

ATP6V1E1

81

P36543
ELLREAKITEELNLR

VPS72

171

Q15906
DIEDEDLKLELRRLR

WNK1

2066

Q9H4A3
VVFRRKLEFLLLSED

ZFYVE26

96

Q68DK2
DFEERKLIRAALREL

SMTN

601

P53814
KLELFLQLRIFERDA

TRIO

781

O75962
VRLELVELVEDLLLK

TTI1

306

O43156
LERIRTLLELEKAER

KDM5C

1431

P41229
IDFLRRLYEEEILIL

KRT81

236

Q14533