Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	S1	TTC14 DHX8 SUPT6H	5.39e-05	10	146	3	PS50126
Domain	DDI1_N	DDI2 DDI1	6.07e-05	2	146	2	IPR033882
Domain	S1	TTC14 DHX8 SUPT6H	9.78e-05	12	146	3	SM00316
Domain	S1_dom	TTC14 DHX8 SUPT6H	9.78e-05	12	146	3	IPR022967
Domain	S1_domain	TTC14 DHX8 SUPT6H	9.78e-05	12	146	3	IPR003029
Domain	HDAC4_Gln	HDAC9 HDAC4	1.81e-04	3	146	2	PF12203
Domain	Hist_deacetylase_Gln_rich_N	HDAC9 HDAC4	1.81e-04	3	146	2	IPR024643
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SETD1A LRWD1 RASA3 ZZEF1 PKMYT1 LPIN3 MST1R JUND VAC14 FASN KMT2D MAP1S ZNF827 AHNAK ZNF335 TIGD3 CEP131 BCAM ZNF579 IQGAP3 RAI1 BAHCC1 SYMPK	4.45e-10	1105	150	23	35748872
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	ANKFY1 ABCA13 FBF1 TOGARAM1 CRTC1 SRSF11 EPS8L1 GHR VAC14 DDX46 SHROOM1 MAP1S LMNB1 MYO18B	6.57e-10	361	150	14	26167880
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	KIFBP GHDC WFS1 DNAJC16 ELP1 QRICH1 CLSTN1 STX12 FANCD2 VAC14 FASN LMNB1 XPO5 TMEM143 CORO7 VPS51 IQGAP3 ZMYM3 SYMPK	2.75e-08	942	150	19	31073040
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MXRA5 TOPAZ1 VPS13C LAMA1 LARP1 DDI2 NBEA SPAG9 ZZEF1 FAM186B USP20 LMNB1 DQX1 AHNAK RAI1 SYMPK	1.36e-07	736	150	16	29676528
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	KIFBP LRWD1 ILF3 DCTN2 ELP1 SRSF11 DHX8 FANCD2 FASN DDX46 XPO5 AHNAK VPS51 SYMPK	2.58e-07	582	150	14	20467437
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	GPHN KNTC1 LRWD1 ILF3 DCTN2 LARP1 SPAG9 SPECC1 PKMYT1 FASN DDX46 MAP1S LMNB1 AHNAK CEP131 IQGAP3 ZMYM3 ANAPC4 STK25	6.29e-07	1155	150	19	20360068
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ELP1 LARP1 SPAG9 DHX8 FASN DDX46 XPO5 SUPT6H AHNAK ZNF512 ZMYM3 CAP1 RAI1 SYMPK	1.01e-06	653	150	14	22586326
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	GPHN PRUNE2 KNTC1 KIFBP ANKFY1 DCTN2 ELP1 LARP1 APEX1 DDI2 SPAG9 QRICH1 ZZEF1 RPP25 FANCD2 FASN MAP1S LMNB1 XPO5 AHNAK CAP1	1.27e-06	1455	150	21	22863883
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	LRWD1 ILF3 LARP1 SPAG9 FANCD2 JUND FASN KMT2D DDX46 MAP1S ZNF335 TRAPPC10 ZNF579 ZMYM3 SYMPK	1.43e-06	774	150	15	15302935
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	KNTC1 FKBP15 KIFBP LRCH2 HDAC4 FBF1 ELP1 LARP1 MAP1S TRAPPC10 CEP131	4.11e-06	446	150	11	24255178
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	NCOA2 GPHN KIFBP LRWD1 PLEKHG4 LARP1 SPAG9 QRICH1 JUND FASN KMT2D LRP1 ZBTB10 ZMYM3 SYMPK	4.94e-06	857	150	15	25609649
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NCOA2 GPHN SETD1A DCTN2 LARP1 SPAG9 FASN KMT2D DDX46 LMNB1 AHNAK SYMPK	5.10e-06	549	150	12	38280479
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	NCOA2 KNTC1 LRWD1 ILF3 HDAC4 MBNL1 GATA1 LARP1 APEX1 QRICH1 JUND FASN KMT2D XPO5 ZMYM3 CAP1 RAI1	6.06e-06	1103	150	17	34189442
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	GPHN FKBP15 KIFBP LRCH2 HDAC4 DCTN2 MBNL1 LARP1 CRTC1 IFT46 SPAG9 LPIN3 XPO5 AHNAK TRAPPC10 CEP131 VPS51 IQGAP3	1.68e-05	1321	150	18	27173435
Pubmed	Knockdown of Ron kinase inhibits mutant phosphatidylinositol 3-kinase and reduces metastasis in human colon carcinoma.	MST1R PIK3CG	1.85e-05	2	150	2	19224914
Pubmed	Histone deacetylase 4 promotes type I interferon signaling, restricts DNA viruses, and is degraded via vaccinia virus protein C6.	HDAC4 STAT2	1.85e-05	2	150	2	31127039
Pubmed	The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development.	KMT2D CD19	1.85e-05	2	150	2	26366710
Pubmed	Deubiquitinases USP20/33 promote the biogenesis of tail-anchored membrane proteins.	USP20 USP33	1.85e-05	2	150	2	33792613
Pubmed	LncRNA CANT1 suppresses retinoblastoma progression by repellinghistone methyltransferase in PI3Kγ promoter.	SETD1A PIK3CG	1.85e-05	2	150	2	32366932
Pubmed	Minihelix-containing RNAs mediate exportin-5-dependent nuclear export of the double-stranded RNA-binding protein ILF3.	ILF3 XPO5	1.85e-05	2	150	2	14570900
Pubmed	Phospholipase D activity underlies very-low-density lipoprotein (VLDL)-induced aldosterone production in adrenal glomerulosa cells.	GPLD1 PLD2	1.85e-05	2	150	2	24956203
Pubmed	Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2.	SETD1A FANCD2	1.85e-05	2	150	2	29937342
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SETD1A KIFBP BRPF3 VPS13C FBF1 LARP1 CRTC1 ZZEF1 DDX46 SUPT6H RAI1	2.02e-05	529	150	11	14621295
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	ANKFY1 ILF3 DNAJC16 ELP1 SPAG9 FASN DDX46 LMNB1 XPO5 SUPT6H CAP1 SYMPK	2.27e-05	638	150	12	33239621
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	TOPAZ1 VPS13C ITGB3 RYR2 DERL3 PROX2 CEP131	2.66e-05	199	150	7	23382691
Pubmed	Identification of the ankyrin repeat proteins ANKRA and RFXANK as novel partners of class IIa histone deacetylases.	HDAC9 HDAC4 MAP1S	2.76e-05	14	150	3	15964851
Pubmed	Impact of WIN site inhibitor on the WDR5 interactome.	SETD1A SPECC1 HELB KMT2D	3.60e-05	43	150	4	33472061
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	KNTC1 KIFBP ANKFY1 ILF3 VPS13C ELP1 LARP1 STX12 DHX8 FANCD2 FASN LMNB1 XPO5 SUPT6H MYO18B ZNF512 IQGAP3 CAP1	4.53e-05	1425	150	18	30948266
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GPHN ILF3 LRCH2 WFS1 DCTN2 ELP1 LARP1 NBEA BCAN SPECC1 FASN MAP1S SLC27A1 SCN2A TRAPPC10 CORO7 VPS51 CAP1	4.78e-05	1431	150	18	37142655
Pubmed	Voltage-gated sodium channels in taste bud cells.	SCN2A SCN9A	5.53e-05	3	150	2	19284629
Pubmed	Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome.	DDI2 DDI1	5.53e-05	3	150	2	29788202
Pubmed	Blocking the association of HDAC4 with MAP1S accelerates autophagy clearance of mutant Huntingtin.	HDAC4 MAP1S	5.53e-05	3	150	2	26540094
Pubmed	An Essential Role for the Tumor-Suppressor Merlin in Regulating Fatty Acid Synthesis.	CRTC1 FASN	5.53e-05	3	150	2	28729415
Pubmed	HDAC4 deacetylase associates with and represses the MEF2 transcription factor.	HDAC9 HDAC4	5.53e-05	3	150	2	10487761
Pubmed	Identification of a deubiquitinating enzyme subfamily as substrates of the von Hippel-Lindau tumor suppressor.	USP20 USP33	5.53e-05	3	150	2	12056827
Pubmed	Pivotal advance: CEACAM1 is a negative coreceptor for the B cell receptor and promotes CD19-mediated adhesion of B cells in a PI3K-dependent manner.	CD19 PIK3CG	5.53e-05	3	150	2	19454653
Pubmed	Different class IIa HDACs repressive complexes regulate specific epigenetic responses related to cell survival in leiomyosarcoma cells.	HDAC9 HDAC4	5.53e-05	3	150	2	31754707
Pubmed	UBX Domain Protein 6 Positively Regulates JAK-STAT1/2 Signaling.	UBXN6 STAT2	5.53e-05	3	150	2	34021047
Pubmed	The co-existence of transcriptional activator and transcriptional repressor MEF2 complexes influences tumor aggressiveness.	HDAC9 HDAC4	5.53e-05	3	150	2	28419090
Pubmed	HDAC1, HDAC4, and HDAC9 Bind to PC3/Tis21/Btg2 and Are Required for Its Inhibition of Cell Cycle Progression and Cyclin D1 Expression.	HDAC9 HDAC4	5.53e-05	3	150	2	27333946
Pubmed	The histone chaperone Spt6 is required for activation-induced cytidine deaminase target determination through H3K4me3 regulation.	SETD1A SUPT6H	5.53e-05	3	150	2	22843687
Pubmed	Deubiquitination of type 2 iodothyronine deiodinase by von Hippel-Lindau protein-interacting deubiquitinating enzymes regulates thyroid hormone activation.	USP20 USP33	5.53e-05	3	150	2	12865408
Pubmed	Cap-independent translation of GPLD1 enhances markers of brain health in long-lived mutant and drug-treated mice.	GPLD1 GHR	5.53e-05	3	150	2	35930768
Pubmed	Dephosphorylation at a conserved SP motif governs cAMP sensitivity and nuclear localization of class IIa histone deacetylases.	HDAC9 HDAC4	5.53e-05	3	150	2	23297420
Pubmed	Nucleocytoplasmic shuttling of JAZ, a new cargo protein for exportin-5.	ILF3 XPO5	5.53e-05	3	150	2	15254228
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRUNE2 HDAC9 KNTC1 TTC14 TOGARAM1 SPAG9 CLSTN1 USP20 ZNF512 TMEM63A	5.97e-05	493	150	10	15368895
Pubmed	The nuclear localization pattern and interaction partners of GTF2IRD1 demonstrate a role in chromatin regulation.	USP20 FHAD1 ZMYM3 USP33	6.56e-05	50	150	4	26275350
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	GPHN FKBP15 WFS1 DNAJC16 VPS13C NBEA STX12 PKMYT1 VAC14 USP33	7.17e-05	504	150	10	34432599
Pubmed	EML3 is a nuclear microtubule-binding protein required for the correct alignment of chromosomes in metaphase.	LRWD1 MAP1S ANAPC4	7.24e-05	19	150	3	18445686
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	ILF3 DNAJC16 LAMA1 LPIN3 KMT2D AHNAK ZNF335	7.43e-05	234	150	7	36243803
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCOA2 GPHN FKBP15 KIFBP ANKFY1 ILF3 LRCH2 HDAC4 NBEA ZNF394 LMNB1 LRP1 CEP131 RAI1	7.80e-05	963	150	14	28671696
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NCOA2 PRUNE2 CDH26 HDAC4 CRADD RASA3 VPS13C MBNL1 TTC14 LARP1 SRSF11 ZNF827 SUPT6H LRP1 TMEM143 ZNF512 RAI1 TMEM63A	7.93e-05	1489	150	18	28611215
Pubmed	Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules.	HDAC9 HDAC4 RYR2	8.49e-05	20	150	3	21421818
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ANKFY1 CRTC1 FASN KMT2D AHNAK LRP1 ZBTB10 CEP131 ZMYM3	8.97e-05	418	150	9	34709266
Pubmed	Genome-wide YFP fluorescence complementation screen identifies new regulators for telomere signaling in human cells.	KIFBP WFS1 APEX1 EPS8L1 RPP25 ZFP36L1 AHNAK REM2	9.88e-05	330	150	8	21044950
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	NCOA2 MXRA5 ANKFY1 FBF1 ELP1 NBEA RYR2 KMT2D HERC6 ZNF512 RAI1	1.08e-04	638	150	11	31182584
Pubmed	Ubiquitin-specific peptidase 20 targets TRAF6 and human T cell leukemia virus type 1 tax to negatively regulate NF-kappaB signaling.	USP20 USP33	1.10e-04	4	150	2	21525354
Pubmed	Redox-regulated recruitment of the transcriptional coactivators CREB-binding protein and SRC-1 to hypoxia-inducible factor 1alpha.	NCOA2 APEX1	1.10e-04	4	150	2	10594042
Pubmed	HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor.	HDAC9 HDAC4	1.10e-04	4	150	2	10523670
Pubmed	Deacetylation of Glutaminase by HDAC4 contributes to Lung Cancer Tumorigenesis.	HDAC9 HDAC4	1.10e-04	4	150	2	35864951
Pubmed	Three novel spermatogenesis-specific zinc finger genes.	ZNF394 ZNF45	1.10e-04	4	150	2	12860387
Pubmed	mHDA1/HDAC5 histone deacetylase interacts with and represses MEF2A transcriptional activity.	HDAC9 HDAC4	1.10e-04	4	150	2	10748098
Pubmed	The deubiquitinases USP33 and USP20 coordinate beta2 adrenergic receptor recycling and resensitization.	USP20 USP33	1.10e-04	4	150	2	19424180
Pubmed	Class IIa histone deacetylases: conducting development and differentiation.	HDAC9 HDAC4	1.10e-04	4	150	2	19412888
Pubmed	Mfge8 promotes obesity by mediating the uptake of dietary fats and serum fatty acids.	ITGB3 SLC27A1	1.10e-04	4	150	2	24441829
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	SETD1A SPECC1 KMT2D MAP1S SUPT6H AHNAK SYMPK	1.15e-04	251	150	7	31076518
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	NCOA2 ILF3 DCTN2 LARP1 SPAG9 QRICH1 AHNAK CORO7 SYMPK	1.41e-04	444	150	9	34795231
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	VPS13C UBXN6 LARP1 KMT2D LMNB1 CEP131 VPS51	1.57e-04	264	150	7	32814769
Pubmed	C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.	ANKFY1 DCTN2 LARP1 XPO5 CAP1	1.72e-04	119	150	5	35776542
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	NCOA2 HDAC4 MBNL1 QRICH1 JUND KMT2D LMNB1 CAP1 RAI1	1.75e-04	457	150	9	32344865
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	TEPSIN LARP1 SRSF11 ITGB3 AHNAK ZNF579 CORO7 STK25	1.79e-04	360	150	8	33111431
Pubmed	A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.	SCN2A SCN9A	1.83e-04	5	150	2	8812438
Pubmed	Functional interaction between class II histone deacetylases and ICP0 of herpes simplex virus type 1.	HDAC9 HDAC4	1.83e-04	5	150	2	15194749
Pubmed	Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins.	ILF3 XPO5	1.83e-04	5	150	2	11777942
Pubmed	Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4.	HDAC9 HDAC4	1.83e-04	5	150	2	18332106
Pubmed	Altered interaction of HDAC5 with GATA-1 during MEL cell differentiation.	HDAC4 GATA1	1.83e-04	5	150	2	14668799
Pubmed	The proline-rich tyrosine kinase Pyk2 regulates platelet integrin αIIbβ3 outside-in signaling.	ITGB3 PIK3CG	1.83e-04	5	150	2	23216754
Pubmed	Myocyte enhancer factor 2 and class II histone deacetylases control a gender-specific pathway of cardioprotection mediated by the estrogen receptor.	HDAC9 HDAC4	1.83e-04	5	150	2	19893013
Pubmed	Phosphoinositide 3-kinase p110 beta regulates integrin alpha IIb beta 3 avidity and the cellular transmission of contractile forces.	ITGB3 PIK3CG	1.83e-04	5	150	2	19940148
Pubmed	A PTIP-PA1 subcomplex promotes transcription for IgH class switching independently from the associated MLL3/MLL4 methyltransferase complex.	KMT2D CD19	1.83e-04	5	150	2	26744420
Pubmed	A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation.	DCTN2 VAC14	1.83e-04	5	150	2	26950892
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	NCOA2 SETD1A CALCB DCTN2 LARP1 SPAG9 IRX3 FASN LMNB1 CEP131 HS3ST3A1 IQGAP3 SYMPK	1.91e-04	922	150	13	27609421
Pubmed	A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.	FANCD2 FASN LMNB1 XPO5 SYMPK	2.16e-04	125	150	5	21654808
Pubmed	Integral and associated lysosomal membrane proteins.	GPLD1 ANKFY1 AHNAK LRP1 TMEM63A	2.24e-04	126	150	5	17897319
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	GHDC WFS1 STX12 PKMYT1 FASN LMNB1 XPO5 AHNAK SLC27A1 LRP1 BCAM ZNF512 ZMYM3 ANAPC4 SYMPK	2.32e-04	1203	150	15	29180619
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	PRUNE2 NBEA STX12 VAC14 TRAPPC10 VPS51 USP33	2.50e-04	285	150	7	34369648
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	KNTC1 LARP1 FASN XPO5 AHNAK IQGAP3	2.55e-04	202	150	6	33005030
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	NCOA2 KLF12 ANKFY1 MBNL1 GATA1 QRICH1 IRX3 PHF1 JUND PROX2 ZMYM3	2.69e-04	709	150	11	22988430
Pubmed	Promoting anti-tumor immunity by targeting TMUB1 to modulate PD-L1 polyubiquitination and glycosylation.	ANKFY1 SPAG9 FASN LMNB1	2.72e-04	72	150	4	36376293
Pubmed	Calcium regulates transcriptional repression of myocyte enhancer factor 2 by histone deacetylase 4.	HDAC9 HDAC4	2.74e-04	6	150	2	10825153
Pubmed	Gfi-1B promoter remains associated with active chromatin marks throughout erythroid differentiation of human primary progenitor cells.	HDAC9 GATA1	2.74e-04	6	150	2	19522008
Pubmed	Ethanol increases fetal human neurosphere size and alters adhesion molecule gene expression.	LAMA1 ITGB3	2.74e-04	6	150	2	18162078
Pubmed	Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis.	KMT2D CD19	2.74e-04	6	150	2	26366712
Pubmed	GRWD1-WDR5-MLL2 Epigenetic Complex Mediates H3K4me3 Mark and Is Essential for Kaposi's Sarcoma-Associated Herpesvirus-Induced Cellular Transformation.	SETD1A KMT2D	2.74e-04	6	150	2	34933446
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN2A SCN9A	2.74e-04	6	150	2	23652591
Pubmed	Ccdc13 is a novel human centriolar satellite protein required for ciliogenesis and genome stability.	DCTN2 CEP131	2.74e-04	6	150	2	24816561
Pubmed	Control of MEF2 transcriptional activity by coordinated phosphorylation and sumoylation.	HDAC9 HDAC4	2.74e-04	6	150	2	16356933
Pubmed	USP33 regulates centrosome biogenesis via deubiquitination of the centriolar protein CP110.	USP20 USP33	2.74e-04	6	150	2	23486064
Pubmed	CD19 is linked to the integrin-associated tetraspans CD9, CD81, and CD82.	CD19 LRP1	2.74e-04	6	150	2	9804823
Pubmed	A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells.	SRSF11 ZNF335 ZMYM3 EBF4	2.87e-04	73	150	4	22094256
Cytoband	12q13.3	DCTN2 ARHGEF25 STAT2 LRP1	2.43e-05	51	150	4	12q13.3
GeneFamily	Histone deacetylases, class IIA	HDAC9 HDAC4	1.70e-04	4	97	2	992
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN2A SCN9A	1.00e-03	9	97	2	1203
CoexpressionAtlas	dev gonad_e12.5_F_SupCellPrec_Sry_k-means-cluster#2_top-relative-expression-ranked_100	IRX3 RYR2 HS3ST3A1 CSGALNACT1	1.24e-05	21	148	4	gudmap_dev gonad_e12.5_F_SupCellPrec_Sry_k2_100
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TOPAZ1 VPS13C RYR2 JUND ZFP36L1 AHNAK SCN2A LRP1	2.34e-07	186	150	8	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	GPHN AADAC ITGB3 PKMYT1 RPP25 CD19 ZNF45	1.55e-06	166	150	7	f4698fd08965936d51695d571bd10fb77330d916
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RABEPK CALCB COL20A1 LAMA1 BCAN HS3ST3A1 REM2	2.04e-06	173	150	7	23e50492bc673aff9df95d97f0b9be4ce57cbf01
ToppCell	mild\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	VPS13C MBNL1 SRSF11 SPAG9 STAT2 JUND AHNAK	5.31e-06	200	150	7	12f1685ce8f218433068e090c9d839cd5a1910bf
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	ILF3 VPS13C MBNL1 SPAG9 JUND AHNAK TRAPPC10	5.31e-06	200	150	7	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	BCAN RYR2 FASN SCN2A SCN9A MDGA1 EBF4	5.31e-06	200	150	7	5c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	CRTC1 RGS12 USP20 PHF1 SHROOM1 SLC27A1	1.44e-05	155	150	6	a4f2fffa8d0de760c556c3f8f1c91804eedbfa68
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AADAC BRPF3 PCDHGC4 GHDC SPECC1 LRP1	1.73e-05	160	150	6	56e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AADAC BRPF3 PCDHGC4 GHDC SPECC1 LRP1	1.73e-05	160	150	6	bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_A2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	HDAC9 IRX3 LPIN3 FHAD1 IQGAP3 BAHCC1	1.79e-05	161	150	6	8ec923c230a7a3cce5edf2a736b3a00d607c698a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 PKMYT1 FANCD2 LMNB1 CEP131 IQGAP3	2.05e-05	165	150	6	88681101d7cf60b99b8ace5d8c0944323b937306
ToppCell	facs-Marrow-B-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA1 CRTC1 EPS8L1 TRAPPC10 ZNF579 ZNF512	2.12e-05	166	150	6	13027ae342994db4540e64eb910df1f42b160931
ToppCell	facs-Marrow-B-cells-24m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA1 CRTC1 EPS8L1 TRAPPC10 ZNF579 ZNF512	2.12e-05	166	150	6	b21e45bd43f26149b9cd6e45c19241c82d54fb2f
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|343B / Donor, Lineage, Cell class and subclass (all cells)	ITGB3 PKMYT1 RPP25 FANCD2 ZNF45 IQGAP3	2.20e-05	167	150	6	7efa0081e79f22b219eac64ffcaedb2179cde299
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 RIBC2 PKMYT1 FANCD2 LMNB1 IQGAP3	2.35e-05	169	150	6	0bc8ef341ce307b19018d4ac8de0a4d04254209d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 RIBC2 PKMYT1 FANCD2 LMNB1 IQGAP3	2.77e-05	174	150	6	84da9faff088d05233183b425385beb054c92d1b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 PKMYT1 FANCD2 LMNB1 DERL3 IQGAP3	3.25e-05	179	150	6	80112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 RIBC2 FANCD2 LMNB1 SCN2A IQGAP3	3.35e-05	180	150	6	401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KNTC1 PKMYT1 FANCD2 LMNB1 DERL3 IQGAP3	3.35e-05	180	150	6	f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CBARP IRX3 CLSTN1 JUND ZFP36L1 BCAM	4.02e-05	186	150	6	bd1185592aedebccd1007dbf2dd2f549fcdf9f42
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRCH2 WFS1 RAPGEF5 SCN9A CSGALNACT1 GRAP	4.02e-05	186	150	6	40070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 KLF12 ARHGEF25 RYR2 GHR HS3ST3A1	4.27e-05	188	150	6	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	PRUNE2 HDAC9 KLF12 RAPGEF5 MBNL1 RYR2	4.27e-05	188	150	6	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	facs-Mammary_Gland-Mammary_Gland-21m-Epithelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CBARP IRX3 CLSTN1 JUND ZFP36L1 BCAM	4.40e-05	189	150	6	965e0e388251e7318f8b463816dc96ccb4658677
ToppCell	PBMC-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	KNTC1 ITGB3 PKMYT1 LMNB1 DERL3 IQGAP3	4.40e-05	189	150	6	946c95d2ecc36b241f58e8c4ad6455fe47c762fa
ToppCell	Mild/Remission-B_activate-7\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MBNL1 STAT2 JUND ZFP36L1 ZBTB10 HERC6	4.66e-05	191	150	6	382686d62f7b8576c44bb9726a4e10dc26fd348e
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIBC2 PKMYT1 FANCD2 LMNB1 DRAXIN IQGAP3	4.66e-05	191	150	6	50854384fdaa0efa2e3227659d544ed09ac102f2
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 KLF12 ARHGEF25 RYR2 GHR HS3ST3A1	4.80e-05	192	150	6	992d08092edbc68c47b945deb8708379738c239a
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-E\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	PRUNE2 MXRA5 ERICH3 DDX46 ZNF827 SCN9A	5.08e-05	194	150	6	8985095f291c1b54e45f4edece49aa26e8c8b732
ToppCell	Mild/Remission-B_activate-7\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	MBNL1 STAT2 JUND ZFP36L1 ZBTB10 HERC6	5.08e-05	194	150	6	01c97543972159a9468272da06e7e611e2c21fae
ToppCell	COVID-19_Mild-PLT_5\|COVID-19_Mild / Disease Group and Platelet Clusters	FKBP15 PLBD1 ILF3 HDAC4 ELP1 AHNAK	5.23e-05	195	150	6	bdf9a6ea1bd83c72a834c45f86ce3f4643a9bef3
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)\|renal_medulla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8L1 CLSTN1 STAT2 JUND BCAM HERC6	5.23e-05	195	150	6	633c7668fe365f7b0f7851cdc442d5dd89c454e2
ToppCell	(0)_NK_cells-(0)_NK_CD160pos\|(0)_NK_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)	HDAC9 MBNL1 CRTC1 DENND2D SPECC1 ZFP36L1	5.23e-05	195	150	6	6cbeceb52bb207f3c074e57b5b3f7cfb24fd5877
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 CBARP ARHGEF25 SPECC1 RYR2 CSGALNACT1	5.53e-05	197	150	6	cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class (2021.03.09)	VPS13C SPAG9 STAT2 JUND ZNF394 HERC6	5.69e-05	198	150	6	44417089b62056269cac38d3134ff209c05b7007
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RABEPK CALCB COL20A1 NBEA BCAN SCN9A	5.69e-05	198	150	6	c506334d81af672ef9ddc8c4fd2a790bdb58e63e
ToppCell	PBMC-Mild\|PBMC / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	VPS13C SPAG9 STAT2 JUND ZNF394 HERC6	5.69e-05	198	150	6	28ef3fc4c17dcb765537b75917f7db78baa522db
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-A_(AT2)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	AADAC MBNL1 SPAG9 IRX3 JUND FASN	5.85e-05	199	150	6	09cf004032e5af912ee0cdde6e24ce3bcf7673cd
ToppCell	Biopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	KNTC1 PKMYT1 FANCD2 FASN LMNB1 IQGAP3	5.85e-05	199	150	6	4fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCell	BAL-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	PLBD1 MBNL1 APEX1 ZFP36L1 PIK3CG CAP1	5.85e-05	199	150	6	da180aaa53f995183522da0f2321bf0c0c8ee6ec
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	BCAN RYR2 FASN SCN2A SCN9A MDGA1	6.02e-05	200	150	6	61d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCell	Macroglial-Polydendrocytes-PDGFRA-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	KLF12 COL20A1 BCAN GHR SCN2A SCN9A	6.02e-05	200	150	6	f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCell	Macroglial-Polydendrocytes-PDGFRA--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	KLF12 COL20A1 BCAN GHR SCN2A SCN9A	6.02e-05	200	150	6	cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	PRUNE2 ARHGEF25 RYR2 GHR LRP1 HS3ST3A1	6.02e-05	200	150	6	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	Macroglial-Polydendrocytes-PDGFRA\|Macroglial / cells hierarchy compared to all cells using T-Statistic	KLF12 COL20A1 BCAN GHR SCN2A SCN9A	6.02e-05	200	150	6	c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCell	Macroglial-Polydendrocytes-PDGFRA---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	KLF12 COL20A1 BCAN GHR SCN2A SCN9A	6.02e-05	200	150	6	4fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCell	Macroglial-Polydendrocytes-PDGFRA----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	KLF12 COL20A1 BCAN GHR SCN2A SCN9A	6.02e-05	200	150	6	310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCell	Macroglial-Polydendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	KLF12 COL20A1 BCAN GHR SCN2A SCN9A	6.02e-05	200	150	6	961858738ce35db8760c8c2e136f8369bc444ccf
Drug	(-)-Adenosine 3',5'-cyclic monophosphate [60-92-4]; Down 200; 12.2uM; MCF7; HT_HG-U133A	CRADD RIBC2 FPGS BCAN EPS8L1 RYR2 JUND MAP1S BCAM HERC6 ZMYM3	8.47e-08	198	150	11	5533_DN
Drug	Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; PC3; HT_HG-U133A	HDAC9 PLBD1 EPS8L1 USP20 RYR2 JUND ZFP36L1 SCN9A BCAM	5.80e-06	194	150	9	4248_DN
Drug	Vinpocetine [42971-09-5]; Up 200; 11.4uM; MCF7; HT_HG-U133A	HDAC4 EPS8L1 ITGB3 RGS12 SLC9A5 ZNF45 PIK3CG VRTN SYMPK	6.57e-06	197	150	9	3174_UP
Drug	Vitamin K2 [11032-49-8]; Up 200; 9uM; PC3; HT_HG-U133A	PRUNE2 GPLD1 KLF12 RAPGEF5 DNAJC16 EPS8L1 RGS12 BCAM SYMPK	6.57e-06	197	150	9	3798_UP
Drug	Apomorphine hydrochloride hemihydrate [41372-20-7]; Up 200; 6.4uM; HL60; HG-U133A	KLF12 UBXN6 DENND2D ITGB3 ZNF335 CEP131 PLD2 BAHCC1 TMEM63A	6.84e-06	198	150	9	2005_UP
Drug	0179445-0000 [211246-22-9]; Down 200; 10uM; PC3; HT_HG-U133A	HDAC9 HDAC4 DENND2D USP20 STAT2 RPP25 BAHCC1 SYMPK	3.74e-05	189	150	8	3733_DN
Drug	geldanamycin; Down 200; 1uM; PC3; HT_HG-U133A	RIBC2 ELP1 DENND2D PKMYT1 JUND SLC9A5 PLD2 TMEM63A	3.89e-05	190	150	8	4452_DN
Drug	PHA-00851261E [724719-49-7]; Down 200; 10uM; PC3; HT_HG-U133A	SETD1A FPGS LARP1 VAC14 ZFP36L1 SUPT6H BCAM TMEM63A	4.19e-05	192	150	8	4330_DN
Drug	0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A	CRTC1 USP20 JUND FASN ZFP36L1 LRP1 PLD2 BCAM	4.51e-05	194	150	8	4331_DN
Drug	PF-00539745-00 [351321-33-0]; Down 200; 10uM; PC3; HT_HG-U133A	GPLD1 SETD1A CBARP EPS8L1 RGS12 STAT2 JUND SYMPK	4.67e-05	195	150	8	5979_DN
Drug	Flufenamic acid [530-78-9]; Up 200; 14.2uM; PC3; HT_HG-U133A	NCOA2 PLBD1 DENND2D PHF1 JUND LMNB1 SYMPK TMEM63A	4.67e-05	195	150	8	2104_UP
Drug	Diphemanil methylsulfate [62-97-5]; Up 200; 10.2uM; PC3; HT_HG-U133A	PLBD1 CRTC1 CBARP RGS12 RYR2 RPP25 ZFP36L1 AHNAK	4.85e-05	196	150	8	4591_UP
Drug	Methotrexate [59-05-2]; Up 200; 8.8uM; PC3; HT_HG-U133A	GPLD1 SETD1A CRTC1 EPS8L1 ITGB3 SLC9A5 AHNAK ZNF335	4.85e-05	196	150	8	6318_UP
Drug	Adrenosterone [382-45-6]; Up 200; 13.4uM; PC3; HT_HG-U133A	PRUNE2 KLF12 RAPGEF5 ZZEF1 RGS12 USP20 BAHCC1 TMEM63A	5.02e-05	197	150	8	5045_UP
Drug	LY 294002; Down 200; 0.1uM; MCF7; HT_HG-U133A	HDAC4 CRADD UBXN6 ZZEF1 JUND VAC14 MAP1S LMNB1	5.02e-05	197	150	8	1641_DN
Drug	N-Acetyl-DL-homocysteine Thiolactone [1195-16-0]; Down 200; 25.2uM; MCF7; HT_HG-U133A	NCOA2 CRTC1 USP20 ZNF45 ZNF335 BCAM HERC6 TMEM63A	5.21e-05	198	150	8	6031_DN
Drug	Metolazone [17560-51-9]; Down 200; 11uM; MCF7; HT_HG-U133A	RIBC2 RGS12 USP20 ZFP36L1 ZNF45 HS3ST3A1 SYMPK TMEM63A	5.21e-05	198	150	8	5392_DN
Drug	Tridihexethyl chloride; Up 200; 11.4uM; PC3; HT_HG-U133A	RAPGEF5 DCTN2 EPS8L1 ZZEF1 RGS12 RYR2 JUND LRP1	5.21e-05	198	150	8	5067_UP
Drug	Althiazide [5588-16-9]; Down 200; 10.4uM; MCF7; HT_HG-U133A	SETD1A ELP1 BCAN EPS8L1 ZFP36L1 HS3ST3A1 BAHCC1 SYMPK	5.21e-05	198	150	8	6089_DN
Drug	Nitrendipine [39562-70-4]; Down 200; 11uM; MCF7; HT_HG-U133A	NCOA2 GPLD1 CRTC1 RGS12 RYR2 SUPT6H SYMPK TMEM63A	5.21e-05	198	150	8	5405_DN
Drug	Bucladesine sodium salt [16980-89-5]; Up 200; 7.8uM; PC3; HT_HG-U133A	PLBD1 CRTC1 ZZEF1 ZFP36L1 PLD2 BAHCC1 SYMPK TMEM63A	5.21e-05	198	150	8	5886_UP
Drug	Ungerine nitrate; Up 200; 10.2uM; MCF7; HT_HG-U133A	PRUNE2 GPLD1 KLF12 RAPGEF5 ZZEF1 ITGB3 RGS12 CSGALNACT1	5.39e-05	199	150	8	6076_UP
Drug	Famprofazone [22881-35-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A	GPLD1 KLF12 RASA3 RAPGEF5 DNAJC16 CRTC1 RGS12 SYMPK	5.59e-05	200	150	8	6029_UP
Drug	Propantheline bromide [50-34-0]; Up 200; 9uM; MCF7; HT_HG-U133A	KLF12 ZZEF1 RYR2 SLC9A5 AHNAK BCAM SYMPK TMEM63A	5.59e-05	200	150	8	3352_UP
Drug	CP-60	GPLD1 LMNB1 SCN2A PLD2	7.20e-05	34	150	4	CID000452626
Disease	myelodysplastic syndrome (is_marker_for)	GATA1 SRSF11 ITGB3	1.22e-04	20	144	3	DOID:0050908 (is_marker_for)
Disease	hair colour measurement	HDAC9 ILF3 HDAC4 RASA3 MBNL1 ITGB3 KMT2D ZFP36L1 AHNAK LRP1 CSGALNACT1	2.27e-04	615	144	11	EFO_0007822
Disease	Intellectual Disability	SETD1A KIFBP HDAC4 LAMA1 NBEA QRICH1 FASN ZNF335 RAI1	3.64e-04	447	144	9	C3714756
Disease	pulse pressure measurement	HDAC9 BRPF3 MXRA5 CRADD MBNL1 DDI2 NBEA ARHGEF25 FAM186B DHX8 VAC14 FASN ZNF827 SUPT6H LRP1 CORO7 STK25	4.63e-04	1392	144	17	EFO_0005763
Disease	forced expiratory volume	HDAC9 SETD1A ILF3 HDAC4 CRADD LARP1 DENND2D RYR2 AHNAK VRTN CSGALNACT1 ANAPC4	5.10e-04	789	144	12	EFO_0004314
Disease	Profound Mental Retardation	KIFBP HDAC4 LAMA1 FASN RAI1	6.15e-04	139	144	5	C0020796
Disease	Mental Retardation, Psychosocial	KIFBP HDAC4 LAMA1 FASN RAI1	6.15e-04	139	144	5	C0025363
Disease	Mental deficiency	KIFBP HDAC4 LAMA1 FASN RAI1	6.15e-04	139	144	5	C0917816
Disease	Autism Spectrum Disorders	ITGB3 RYR2 IQGAP3 RAI1	8.11e-04	85	144	4	C1510586
Disease	Generalized Epilepsy with Febrile Seizures Plus	SCN2A SCN9A	8.33e-04	9	144	2	C3502809
Disease	diffuse scleroderma	VAC14 ZNF394	8.33e-04	9	144	2	EFO_0000404
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN2A SCN9A	1.04e-03	10	144	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN2A SCN9A	1.04e-03	10	144	2	DOID:0080422 (implicated_via_orthology)
Disease	serum IgG glycosylation measurement	TOPAZ1 VPS13C ITGB3 RYR2 DHX8 DERL3 PROX2 CEP131 MDGA1	1.11e-03	523	144	9	EFO_0005193
Disease	middle cerebral artery infarction (biomarker_via_orthology)	HDAC9 HDAC4 CRTC1 BCAN	1.13e-03	93	144	4	DOID:3525 (biomarker_via_orthology)
Disease	eye measurement, sun exposure measurement	HDAC9 SPAG9	1.26e-03	11	144	2	EFO_0004731, EFO_0010729
Disease	gastric adenocarcinoma (is_implicated_in)	ABCA13 KMT2D	1.26e-03	11	144	2	DOID:3717 (is_implicated_in)
Disease	Schizophrenia	HDAC9 SETD1A KLF12 HDAC4 ABCA13 MBNL1 LAMA1 ITGB3 RGS12 LRP1 MDGA1 RAI1	1.35e-03	883	144	12	C0036341
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN2A SCN9A	1.51e-03	12	144	2	DOID:0060170 (implicated_via_orthology)
Disease	response to antidepressant	LAMA1 DHX8 SLC27A1 MDGA1 CSGALNACT1	1.76e-03	176	144	5	GO_0036276
Disease	Infantile Severe Myoclonic Epilepsy	SCN2A SCN9A	1.78e-03	13	144	2	C0751122
Disease	cardiotoxicity, response to anthracycline-based chemotherapy	PRUNE2 ILF3	2.07e-03	14	144	2	EFO_0005257, EFO_1001482
Disease	Anilide use measurement	LRP1 STK25	2.38e-03	15	144	2	EFO_0009938
Disease	cutaneous melanoma, hair color	RASA3 ZFP36L1 AHNAK	3.49e-03	62	144	3	EFO_0000389, EFO_0003924
Disease	triglycerides to total lipids in medium VLDL percentage	RGS12 ZNF335 BCAM	3.65e-03	63	144	3	EFO_0022335
Disease	cortical surface area change measurement, age at assessment	SPAG9 VRTN	3.83e-03	19	144	2	EFO_0008007, EFO_0021503
Disease	Cannabis use, age at onset	LARP1 RYR2	3.83e-03	19	144	2	EFO_0004847, EFO_0007585
Disease	diaphragmatic hernia	CRTC1 PHF1	4.67e-03	21	144	2	EFO_0008561
Disease	susceptibility to mononucleosis measurement	HDAC9 RYR2 ANAPC4	4.71e-03	69	144	3	EFO_0008403

Protein segments in the cluster

Peptide	Gene	Start	Entry
LDKLAAGLDERLFPP	CBARP	666	Q8N350
ELSDNPGLLGEDSLK	ERICH3	1136	Q5RHP9
RDGLPVLIPKEDSLL	BAHCC1	1911	Q9P281
RALLPLDKQALGDIP	ARHGEF25	536	Q86VW2
AEDESNLLLPKLPTL	ANAPC4	131	Q9UJX5
PDPATLSKEDARLLL	CALCB	36	P10092
LGLDRSPPEKTQADL	CSGALNACT1	106	Q8TDX6
PLLADDNKLRGLPLT	AADAC	321	P22760
IFLRDEEPLLKSPGA	GRAP	146	Q13588
PAENKLSDLLAPISE	CAP1	96	Q01518
DLPDLPLSDILKGRT	SPECC1	886	Q5M775
LVGKPDILLLDEPSS	ABCA13	4871	Q86UQ4
ELLEKSPLQLGNEPL	BRPF3	881	Q9ULD4
PKLEGELQAPDLELS	AHNAK	5111	Q09666
NTVLLDPPLIALDKD	CLSTN1	51	O94985
GSKDTESLEPVLLPL	FAM186B	406	Q8IYM0
ENKLPAELQELPGLS	APEX1	101	P27695
KLLGPDAAINLTDPD	DCTN2	156	Q13561
TPGFLKLLLDAPAED	DERL3	201	Q96Q80
GDLPLLPPTSRKEDL	RAI1	851	Q7Z5J4
SPLRDLLLKSADVEP	RASA3	301	Q14644
ELLLPNSLKPEEGLE	QRICH1	466	Q2TAL8
TLLKFDTLLPPGRLD	RABEPK	281	Q7Z6M1
LNPEDDLLPGKIRDS	GPHN	511	Q9NQX3
ELLGEDLPLEPSVTK	SPAG9	1291	O60271
PKLEELSLEGNPFLT	LRWD1	91	Q9UFC0
PLDKPDADGSTVLLL	ANKFY1	1036	Q9P2R3
SRVDKEAALLPSGLP	MDGA1	476	Q8NFP4
DVLADLGSLKPSADP	PCDHGA4	701	Q9Y5G9
LGDPPEKLTLEEARA	BCAN	261	Q96GW7
DLSLLKERNPPLAEA	DDI1	156	Q8WTU0
KERNPPLAEALLSGS	DDI1	161	Q8WTU0
LPKGLSASLPDLDSE	LARP1	541	Q6PKG0
DLTKNPGLLDDPNLV	LPIN3	466	Q9BQK8
ALLGNELDPLPEKVL	HDAC4	991	P56524
IPAGEEKALELPLAA	MAP1S	616	Q66K74
IRGIPLDPNDKSDAL	LRP1	1901	Q07954
APILLPDLEGTKLSN	LINC02693	126	A8MQB3
PDLGLLKLASPELER	JUND	91	P17535
LEGEEERLKLSPSPS	LMNB1	381	P20700
PLLDPDSGLLVLAGK	CORO7	266	P57737
ALSEIKDGSLPPELS	FKBP15	1016	Q5T1M5
TPGTKDPRALLLDAL	GHDC	176	Q8N2G8
KPSLEDLKELSPRLG	HERC6	791	Q8IVU3
RKDPALLSSEAVLPD	DNAJC16	486	Q9Y2G8
PGDLAALPALEELDL	LINGO3	71	P0C6S8
EQGEDCLLLLKSLPP	KNTC1	906	P50748
SLKEGSPLEDLALLE	ELP1	1206	O95163
APPGTLALLLDEGSK	HS3ST3A1	136	Q9Y663
RLPILLKGTSDDDVP	TEPSIN	16	Q96N21
SDGSLVPELLLEKPL	PCDHGC4	186	Q9Y5F7
ILPVNLSGDLLDKDP	TMEM63A	161	O94886
DLSDPLALKKDLPAR	RIBC2	116	Q9H4K1
SEFPLAPELAKALLA	DQX1	466	Q8TE96
ALLLPAAGLDDVSLP	IQGAP3	546	Q86VI3
DLLDLIPSLSPTKNG	PLBD1	201	Q6P4A8
ATPLKLDPLGPLASE	NUTM1	311	Q86Y26
LADLLSPEKQRDPLA	NUTM1	436	Q86Y26
KFLLLGLSDDPELQP	OR7D4	11	Q8NG98
PSGAPASLEILRKEL	PROX2	216	Q3B8N5
LKTERLSPDLLTLGP	GATA1	136	P15976
LLPEQSPAGLLQDKD	DRAXIN	96	Q8NBI3
LGLKDEDLDLFPASP	FBF1	346	Q8TES7
LLDAKPDLPTLSRIE	FHAD1	1196	B1AJZ9
PDNLGLLVLDEPSTK	IFT46	126	Q9NQC8
GLILNATALPLPDKE	GHR	606	P10912
GPKSLLSLELKDDRP	CD19	221	P15391
PLDELKIDPLTLDGL	CRTC1	596	Q6UUV9
DALPRSGLNLKEEPL	EBF4	6	Q9BQW3
SGLNLKEEPLLPAGL	EBF4	11	Q9BQW3
KNADEAELRLLASPP	COL20A1	316	Q9P218
LLLDILPSRGPKAFD	CRADD	56	P78560
ALAALEKLFPDTPLA	ILF3	581	Q12906
LGDELLLAKLPPSRE	FAM131A	276	Q6UXB0
SLKRPLEATFDLGIP	MBNL1	276	Q9NR56
LQPDLLDSLGSKATP	CDH26	806	Q8IXH8
ALPLGSPRCDLKENL	ITGB3	56	P05106
TGDRDPAALLKLLQP	FPGS	416	Q05932
LLLNNVKGEPPEDSL	KLF12	56	Q9Y4X4
NPPLAEALLSGDLEK	DDI2	156	Q5TDH0
PLDGQKLDPRILLGD	HDAC9	706	Q9UKV0
KALELSGTAVPPDLE	DDX46	736	Q7L014
EGLLTLRAKPPSEAE	EPS8L1	301	Q8TE68
RPKLPEDPLLSGLLD	FASN	1206	P49327
EDPLLSGLLDSPALK	FASN	1211	P49327
LDPLELSEGKVLSLP	BCAM	361	P50895
RKPLEAALPSEDLTD	RYR2	4351	Q92736
EPPEDGTLLSEAKLQ	CEP131	516	Q9UPN4
PSIEPGNLLKDLFET	HELB	626	Q8NG08
ALLEEVKALLGPAPE	KIFBP	41	Q96EK5
LIGSEPGPAEELAKL	DHX8	11	Q14562
LPPKLQDDILDSLGQ	DENND2D	346	Q9H6A0
GPPELLFLLEDLSQK	FANCD2	961	Q9BXW9
PDELGDLPLVKLDFS	LRCH2	241	Q5VUJ6
SSEGLEDRPLPVLSL	IRX3	296	P78415
DLPSRVEIKPGDELL	MOXD2P	426	A6NHM9
DSLLLGELSDTPKGE	PHF1	286	O43189
AILLSKDALDPRQPG	RPP25	136	Q9BUL9
PDPNVKSGSELLDRL	VAC14	146	Q08AM6
PELSLDLEPLLKAGL	STAT2	731	P52630
DLEPLLKAGLDLGPE	STAT2	736	P52630
GDPPLEEDSLKQSLA	PRUNE2	2376	Q8WUY3
KPLESLALEEASGPV	PRUNE2	2681	Q8WUY3
LPPEVGDLKELQTLD	LRRC28	126	Q86X40
SGLPKPADCLLAQDL	PLEKHG4	171	Q58EX7
LINGRPSADDLSPKL	LAMA1	201	P25391
NGPLITLADEKEDLP	NBEA	1126	Q8NFP9
KLSDFAAALDPPLLI	SCN9A	1801	Q15858
KDSAAALSDRELPLP	RAPGEF5	16	Q92565
ESDLLKPVPADALGL	SHROOM1	496	Q2M3G4
LSLLALPLAGAAEEP	SLC9A5	6	Q14940
LPPREEAELAEGKTL	SETD1A	771	O15047
GSALDLLKPGPLEET	STK25	101	O00506
PELNGLDSKLLLDLP	STRC	1251	Q7RTU9
DIGLPEITPKLERLD	NCOA2	756	Q15596
TDPLNPLTAEDKELL	PIK3CG	561	P48736
DPDKPLADGIRALDT	SUPT6H	431	Q7KZ85
EKELRNLEAELGPSP	VPS51	281	Q9UID3
EPLPTKADALRALGT	TIGD3	426	Q6B0B8
ILSADDLLGSPTLPD	ZFP36L1	231	Q07352
AGAEPDSILKPELLS	UBXN6	421	Q9BZV1
LPLKLENSPEAEGLN	ZNF394	251	Q53GI3
EKEPLDLGAPISSLD	RGS12	1081	O14924
DTPLEGLEQLLPELK	TMEM143	256	Q96AN5
LGKIDELRLFPPDDS	SRSF11	56	Q05519
EPDPKLRATAEALLA	PKMYT1	341	Q99640
EGILPDTHLLDPLLK	SLC27A1	211	Q6PCB7
ETNELLKELGSLPLP	STX12	76	Q86Y82
AKLSDFADALDPPLL	SCN2A	1816	Q99250
GNDLGLPPVDLDLDK	GPLD1	421	P80108
LDAEKSAILGLPQPL	XPO5	806	Q9HAV4
LLEKLGIDESNPPSL	TTC14	266	Q96N46
PLHLISSSDKPGLDL	VPS13C	976	Q709C8
KLLAELDRSGLPSAP	REM2	46	Q8IYK8
TFQDLSLPIPGKEDL	USP20	471	Q9Y2K6
AALLDSSLEGPLPKE	SYMPK	1216	Q92797
LATVLKPDEGTADLP	MYO18B	526	Q8IUG5
VPPDSKLGQDLLRDA	ZNF200	21	P98182
SLLAEKSSLLPEDPL	ZNF827	301	Q17R98
DPRGLEAAKEAELPL	TOPAZ1	96	Q8N9V7
DKDPGGLLLLPEKND	ZZEF1	906	O43149
IKEEPDLDGALLSGP	ZBTB10	616	Q96DT7
IPRGISLLPDKADLS	TOGARAM1	916	Q9Y4F4
ELKLLEVSVPPGALD	TRAPPC10	341	P48553
SPAKTLELLNREPGL	VRTN	266	Q9H8Y1
KLPRLEISDLPDGVE	ZNF335	356	Q9H4Z2
LKAEQEEEGLPLPLA	ZNF579	491	Q8NAF0
LEDESLLPPLGSKEG	PLD2	911	O14939
NSLPILKAGDEIDEP	ZNF512	221	Q96ME7
GDTDTKVLVLDPALP	MST1R	116	Q04912
STPDGLPQLEREEKL	ZNF45	51	Q02386
ALDLLDTPAGLEKDP	ZMYM3	56	Q14202
TFQDLSLPIPGKEDL	USP33	501	Q8TEY7
PLEGLDLQPFLAKDS	USP33	636	Q8TEY7
DDELAGKSPEDLPLR	WFS1	271	O76024
SELKGSPVLLDPEEL	KMT2D	1146	O14686
GENLTDPPLLKELED	MXRA5	1401	Q9NR99