Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH3 KIF21A SMC3 KIF4B KIF2A DNAH9

2.95e-06701146GO:0003777
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH3 KIF21A MYO1B SMC3 KIF4B KIF2A DNAH9

5.14e-061181147GO:0003774
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

DOCK1 DOCK2 DENND2A DENND4A RAPGEF4 SBF1 DENND2C SH3BP5L DOCK6

7.18e-062311149GO:0005085
GeneOntologyMolecularFunctionphosphatidylinositol binding

IRGM MYO1B KRIT1 ITPR2 ZFYVE9 KCNQ1 EXOC1 DNM1 SNX9 WDFY1

1.36e-0531611410GO:0035091
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

DOCK1 DOCK2 DENND2A DENND4A RAPGEF4 LRRK2 SRGAP2 KRIT1 SBF1 DENND2C SH3BP5L DOCK6

3.33e-0550711412GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

DOCK1 DOCK2 DENND2A DENND4A RAPGEF4 LRRK2 SRGAP2 KRIT1 SBF1 DENND2C SH3BP5L DOCK6

3.33e-0550711412GO:0030695
GeneOntologyMolecularFunctionprofilin binding

PCLO ENAH FMNL1

4.97e-05131143GO:0005522
GeneOntologyMolecularFunctionsmall GTPase binding

DOCK1 DOCK2 RAPGEF4 LRRK2 SRGAP2 FMNL2 DAAM2 ULK1 FMNL1

9.47e-053211149GO:0031267
GeneOntologyMolecularFunction1-phosphatidylinositol binding

ZFYVE9 SNX9 WDFY1

1.16e-04171143GO:0005545
GeneOntologyMolecularFunctionIMP 5'-nucleotidase activity

NT5E NT5C1A

1.92e-0441142GO:0050483
GeneOntologyMolecularFunctionphosphatidylinositol-4,5-bisphosphate binding

MYO1B KRIT1 KCNQ1 EXOC1 DNM1

2.14e-04951145GO:0005546
GeneOntologyMolecularFunctionGTPase binding

DOCK1 DOCK2 RAPGEF4 LRRK2 SRGAP2 FMNL2 DAAM2 ULK1 FMNL1

2.24e-043601149GO:0051020
GeneOntologyMolecularFunctionphospholipid binding

IRGM PCLO MYO1B KRIT1 ITPR2 ZFYVE9 KCNQ1 EXOC1 DNM1 SNX9 WDFY1

3.02e-0454811411GO:0005543
GeneOntologyMolecularFunctionphosphatidylinositol bisphosphate binding

MYO1B KRIT1 KCNQ1 EXOC1 DNM1

6.52e-041211145GO:1902936
GeneOntologyMolecularFunctionXMP 5'-nucleosidase activity

NT5E NT5C1A

8.85e-0481142GO:0106411
GeneOntologyMolecularFunctionphosphatidylinositol phosphate binding

IRGM MYO1B KRIT1 KCNQ1 EXOC1 DNM1

9.93e-041991146GO:1901981
GeneOntologyMolecularFunctioncytoskeletal protein binding

KIF21A LRRK2 MYO1B TUBGCP2 FMNL2 KRIT1 EGFR SMC3 ENAH DAAM2 KIF4B KIF2A DNM1 UTRN FMNL1

1.46e-03109911415GO:0008092
GeneOntologyMolecularFunctionmicrotubule binding

KIF21A LRRK2 TUBGCP2 KRIT1 KIF4B KIF2A DNM1

1.96e-033081147GO:0008017
GeneOntologyMolecularFunctioncalmodulin binding

CACNA1S PDE1B MYO1B EGFR TJP1 KCNQ1

2.08e-032301146GO:0005516
GeneOntologyCellularComponentmicrotubule associated complex

DNAH3 KIF21A HAUS3 KIF4B KIF2A CFAP70 DNAH9

3.44e-051611177GO:0005875
GeneOntologyCellularComponentcone cell pedicle

PCLO RAPGEF4

3.07e-0451172GO:0044316
GeneOntologyCellularComponentaxonemal dynein complex

DNAH3 CFAP70 DNAH9

3.59e-04251173GO:0005858
GeneOntologyCellularComponentmultivesicular body, internal vesicle

LRRK2 EGFR

4.59e-0461172GO:0097487
DomainARM-type_fold

DOCK1 DOCK2 ZYG11A LRRK2 ARMC2 FMNL2 ITPR2 AP4E1 DAAM2 HEATR5B HECTD1 FMNL1

1.11e-0633911412IPR016024
DomainuDENN

DENND2A DENND4A SBF1 DENND2C

1.26e-06141144SM00800
DomainuDENN

DENND2A DENND4A SBF1 DENND2C

1.71e-06151144PF03456
DomainDENN

DENND2A DENND4A SBF1 DENND2C

2.26e-06161144SM00799
DomainDENN

DENND2A DENND4A SBF1 DENND2C

2.26e-06161144PF02141
DomaindDENN

DENND2A DENND4A SBF1 DENND2C

2.26e-06161144PF03455
DomainUDENN

DENND2A DENND4A SBF1 DENND2C

2.26e-06161144PS50946
DomainDDENN

DENND2A DENND4A SBF1 DENND2C

2.26e-06161144PS50947
DomaindDENN

DENND2A DENND4A SBF1 DENND2C

2.26e-06161144SM00801
DomaindDENN_dom

DENND2A DENND4A SBF1 DENND2C

2.26e-06161144IPR005112
DomainuDENN_dom

DENND2A DENND4A SBF1 DENND2C

2.26e-06161144IPR005113
DomainDENN

DENND2A DENND4A SBF1 DENND2C

2.26e-06161144PS50211
DomainDENN_dom

DENND2A DENND4A SBF1 DENND2C

2.26e-06161144IPR001194
DomainDAD_dom

FMNL2 DAAM2 FMNL1

1.21e-0581143IPR014767
DomainDAD

FMNL2 DAAM2 FMNL1

1.21e-0581143PS51231
DomainDrf_GBD

FMNL2 DAAM2 FMNL1

1.81e-0591143PF06371
DomainDrf_FH3

FMNL2 DAAM2 FMNL1

1.81e-0591143PF06367
DomainFH3_dom

FMNL2 DAAM2 FMNL1

1.81e-0591143IPR010472
DomainGTPase-bd

FMNL2 DAAM2 FMNL1

1.81e-0591143IPR010473
DomainDrf_FH3

FMNL2 DAAM2 FMNL1

1.81e-0591143SM01139
DomainDrf_GBD

FMNL2 DAAM2 FMNL1

1.81e-0591143SM01140
DomainGBD/FH3_dom

FMNL2 DAAM2 FMNL1

3.53e-05111143IPR014768
DomainGBD_FH3

FMNL2 DAAM2 FMNL1

3.53e-05111143PS51232
DomainDHR-1_domain

DOCK1 DOCK2 DOCK6

3.53e-05111143IPR027007
DomainDHR_2

DOCK1 DOCK2 DOCK6

3.53e-05111143PS51651
DomainDHR_1

DOCK1 DOCK2 DOCK6

3.53e-05111143PS51650
DomainDHR-2

DOCK1 DOCK2 DOCK6

3.53e-05111143PF06920
DomainDOCK

DOCK1 DOCK2 DOCK6

3.53e-05111143IPR026791
DomainDOCK_C

DOCK1 DOCK2 DOCK6

3.53e-05111143IPR010703
DomainDOCK-C2

DOCK1 DOCK2 DOCK6

3.53e-05111143PF14429
DomainDHR-2

DOCK1 DOCK2 DOCK6

3.53e-05111143IPR027357
DomainFH2

FMNL2 DAAM2 FMNL1

9.55e-05151143PS51444
DomainFH2_Formin

FMNL2 DAAM2 FMNL1

9.55e-05151143IPR015425
DomainFH2

FMNL2 DAAM2 FMNL1

9.55e-05151143PF02181
DomainFH2

FMNL2 DAAM2 FMNL1

9.55e-05151143SM00498
DomainARM-like

DOCK2 ZYG11A LRRK2 ARMC2 AP4E1 DAAM2 HEATR5B HECTD1

2.52e-042701148IPR011989
DomainDOCK_N

DOCK1 DOCK2

3.65e-0451142PF16172
DomainDOCK_N

DOCK1 DOCK2

3.65e-0451142IPR032376
DomainPHR

BTBD6 BTBD3

3.65e-0451142IPR012983
DomainPHR

BTBD6 BTBD3

3.65e-0451142PF08005
Domain-

ZYG11A LRRK2 ARMC2 AP4E1 DAAM2 HEATR5B HECTD1

4.28e-0422211471.25.10.10
DomainKinesin_motor_CS

KIF21A KIF4B KIF2A

1.99e-03411143IPR019821
DomainP-loop_NTPase

IRGM DNAH3 KIF21A GPN1 LRRK2 MYO1B SMC3 TJP1 KIF4B KIF2A DNM1 DNAH9 RAB33B

2.00e-0384811413IPR027417
Domaint-SNARE

MSR1 DAAM2 STX10

2.29e-03431143IPR010989
DomainKinesin-like_fam

KIF21A KIF4B KIF2A

2.29e-03431143IPR027640
Domain-

KIF21A KIF4B KIF2A

2.44e-034411433.40.850.10
DomainKinesin

KIF21A KIF4B KIF2A

2.44e-03441143PF00225
DomainKISc

KIF21A KIF4B KIF2A

2.44e-03441143SM00129
DomainKINESIN_MOTOR_1

KIF21A KIF4B KIF2A

2.44e-03441143PS00411
DomainKinesin_motor_dom

KIF21A KIF4B KIF2A

2.44e-03441143IPR001752
DomainKINESIN_MOTOR_2

KIF21A KIF4B KIF2A

2.44e-03441143PS50067
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH9

3.20e-03141142IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH9

3.20e-03141142IPR024743
DomainDynein_heavy_dom-2

DNAH3 DNAH9

3.20e-03141142IPR013602
DomainDHC_N2

DNAH3 DNAH9

3.20e-03141142PF08393
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH9

3.20e-03141142IPR011704
DomainMT

DNAH3 DNAH9

3.20e-03141142PF12777
DomainAAA_8

DNAH3 DNAH9

3.20e-03141142PF12780
DomainAAA_5

DNAH3 DNAH9

3.20e-03141142PF07728
DomainDHC_fam

DNAH3 DNAH9

3.68e-03151142IPR026983
DomainDynein_heavy

DNAH3 DNAH9

3.68e-03151142PF03028
DomainDynein_heavy_dom

DNAH3 DNAH9

3.68e-03151142IPR004273
DomainIon_trans_dom

TRPM6 CACNA1S ITPR2 KCNQ1

5.25e-031141144IPR005821
DomainIon_trans

TRPM6 CACNA1S ITPR2 KCNQ1

5.25e-031141144PF00520
PathwayREACTOME_MEMBRANE_TRAFFICKING

DENND2A DENND4A KIF21A AP4E1 SBF1 EGFR TJP1 DENND2C KIF4B EXOC1 KIF2A ULK1 DNM1 STX10 SNX9 RAB33B

2.40e-066309116M11480
PathwayREACTOME_VESICLE_MEDIATED_TRANSPORT

DENND2A DENND4A KIF21A MSR1 AP4E1 SBF1 EGFR TJP1 DENND2C KIF4B EXOC1 KIF2A ULK1 DNM1 STX10 SNX9 RAB33B

3.28e-067259117M27507
PathwayREACTOME_VESICLE_MEDIATED_TRANSPORT

DENND2A DENND4A KIF21A MSR1 AP4E1 SBF1 EGFR TJP1 DENND2C KIF4B KIF2A ULK1 DNM1 SNX9 RAB33B

1.48e-056459115MM15232
PathwayREACTOME_FACTORS_INVOLVED_IN_MEGAKARYOCYTE_DEVELOPMENT_AND_PLATELET_PRODUCTION

DOCK1 DOCK2 KIF21A KIF4B KIF2A DOCK6

1.03e-04116916MM15715
PathwayREACTOME_RAB_REGULATION_OF_TRAFFICKING

DENND2A DENND4A SBF1 DENND2C ULK1 RAB33B

1.13e-04118916MM15589
PathwayREACTOME_RAB_REGULATION_OF_TRAFFICKING

DENND2A DENND4A SBF1 DENND2C ULK1 RAB33B

1.36e-04122916M27872
PathwayREACTOME_RAB_GEFS_EXCHANGE_GTP_FOR_GDP_ON_RABS

DENND2A DENND4A SBF1 DENND2C ULK1

2.86e-0490915M27779
PathwayREACTOME_RAB_GEFS_EXCHANGE_GTP_FOR_GDP_ON_RABS

DENND2A DENND4A SBF1 DENND2C ULK1

3.01e-0491915MM15518
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

CCP110 DENND4A SRGAP2 TUBGCP2 SMC3 TJP1 KIF2A DOCK6 HECTD1 UTRN FMNL1

3.50e-074461171124255178
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CCP110 DENND4A SRGAP2 RRM2 SBF1 TJP1 RBM14 SH3BP5L KIF2A DOCK6 HECTD1 UTRN DOP1A DYRK2

1.27e-068611171436931259
Pubmed

Exploring the effects of gene dosage on mandible shape in mice as a model for studying the genetic basis of natural variation.

BMP5 BMP6 EGFR

3.07e-069117323563729
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

DOCK1 UGGT1 MYO1B SBF1 EGFR DOCK6 HECTD1

5.81e-06202117733005030
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

DOCK1 DENND4A AP4E1 ZFYVE9 ULK1 HEATR5B STX10 WDFY1

5.81e-06285117834369648
Pubmed

Family-wide characterization of the DENN domain Rab GDP-GTP exchange factors.

DENND2A DENND4A SBF1 DENND2C

7.37e-0637117420937701
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

UBQLNL DNAH3 PPFIA2 KIF21A PCLO FMNL2 ITPR2 KMT2C ASNS XXYLT1 PKM UTRN

7.46e-067361171229676528
Pubmed

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.

RMND5A ITPR2 SBF1 SMC3 DHPS PIPSL HECTD1

7.96e-06212117733853758
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 MAOA PPFIA2 SRGAP2 ARMC2 KMT2C DAZAP1 EGFR TJP1 ENAH XXYLT1 GPT2 DOCK6 SNX9 HECTD1 UTRN DOP1A

1.03e-0514891171728611215
Pubmed

Nuclear EGFR-PKM2 axis induces cancer stem cell-like characteristics in irradiation-resistant cells.

EGFR PKM

1.12e-052117229477380
Pubmed

Piccolo mediates EGFR signaling and acts as a prognostic biomarker in esophageal squamous cell carcinoma.

PCLO EGFR

1.12e-052117228263981
Pubmed

Targeting Ras-Driven Cancer Cell Survival and Invasion through Selective Inhibition of DOCK1.

DOCK1 DOCK2

1.12e-052117228467910
Pubmed

The transglutaminase type 2 and pyruvate kinase isoenzyme M2 interplay in autophagy regulation.

TGM2 PKM

1.12e-052117226702927
Pubmed

Identification and characterization of human DAAM2 gene in silico.

DAAM2 FMNL1

1.12e-052117212632087
Pubmed

Human Mena+11a isoform serves as a marker of epithelial phenotype and sensitivity to epidermal growth factor receptor inhibition in human pancreatic cancer cell lines.

EGFR ENAH

1.12e-052117218676769
Pubmed

EGFR-PKM2 signaling promotes the metastatic potential of nasopharyngeal carcinoma through induction of FOSL1 and ANTXR2.

EGFR PKM

1.12e-052117231665243
Pubmed

Redifferentiation and ZO-1 reexpression in liver-metastasized colorectal cancer: possible association with epidermal growth factor receptor-induced tyrosine phosphorylation of ZO-1.

EGFR TJP1

1.12e-052117212708492
Pubmed

Critical roles for multiple formins during cardiac myofibril development and repair.

FMNL2 FMNL1

1.12e-052117224430873
Pubmed

ULK1 and JNK are involved in mitophagy incurred by LRRK2 G2019S expression.

LRRK2 ULK1

1.12e-052117227023913
Pubmed

Myo1b Promotes Premature Endothelial Senescence and Dysfunction via Suppressing Autophagy: Implications for Vascular Aging.

LRRK2 MYO1B

1.12e-052117236654782
Pubmed

EGFRvIII stimulates glioma growth and invasion through PKA-dependent serine phosphorylation of Dock180.

DOCK1 EGFR

1.12e-052117223728337
Pubmed

PKM2 regulates hepatocellular carcinoma cell epithelial-mesenchymal transition and migration upon EGFR activation.

EGFR PKM

1.12e-052117224716919
Pubmed

Overexpression of phospho mutant forms of transglutaminase 2 downregulates epidermal growth factor receptor.

TGM2 EGFR

1.12e-052117222142843
Pubmed

Scaffold stiffness influences breast cancer cell invasion via EGFR-linked Mena upregulation and matrix remodeling.

EGFR ENAH

1.12e-052117231323325
Pubmed

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.

UGGT1 TGM2 SMC3 TJP1 RBM14 SNX9 UTRN

1.21e-05226117737839992
Pubmed

Expression of multiple formins in adult tissues and during developmental stages of mouse brain.

FMNL2 DAAM2 FMNL1

1.31e-0514117326272686
Pubmed

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity.

DOCK1 DOCK2 DOCK6

1.31e-0514117312432077
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

NT5E UGGT1 SRGAP2 FMNL2 TGM2 DAZAP1 EGFR SMC3 TJP1 RBM14 KIF2A

1.49e-056601171132780723
Pubmed

A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.

UGGT1 MYO1B TUBGCP2 SMC3 ASNS ENAH EXOC1 PRMT3 SUZ12 SNX9

2.07e-055601171035241646
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DENND2A PPFIA2 PCLO RAPGEF4 SRGAP2 FMNL2 ITPR2 OR52E2 SBF1 TJP1 RBM14 PKM EXOC1 KIF2A DNM1 UTRN

2.49e-0514311171637142655
Pubmed

Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.

MAOA MYO1B RRM2 TJP1 ASNS RBM14 PKM

3.27e-05264117732814769
Pubmed

Role of DOCK2 and DOCK180 in fetal thymus colonization.

DOCK1 DOCK2

3.36e-053117219728314
Pubmed

A bone morphogenetic protein subfamily: chromosomal localization of human genes for BMP5, BMP6, and BMP7.

BMP5 BMP6

3.36e-05311721427904
Pubmed

SNX9 regulates dynamin assembly and is required for efficient clathrin-mediated endocytosis.

DNM1 SNX9

3.36e-053117215703209
Pubmed

EGFR Signals through a DOCK180-MLK3 Axis to Drive Glioblastoma Cell Invasion.

DOCK1 EGFR

3.36e-053117228487380
Pubmed

Leucine-rich repeat kinase 2 binds to neuronal vesicles through protein interactions mediated by its C-terminal WD40 domain.

LRRK2 DNM1

3.36e-053117224687852
Pubmed

Inhibition of transglutaminase 2 reduces efferocytosis in human macrophages: Role of CD14 and SR-AI receptors.

MSR1 TGM2

3.36e-053117227378395
Pubmed

Bone Morphogenetic Protein (BMP) signaling in development and human diseases.

BMP5 BMP6

3.36e-053117225401122
Pubmed

Epidermal growth factor receptor and podocin predict nephropathy progression in type 2 diabetic patients through interaction with the autophagy influencer ULK-1.

EGFR ULK1

3.36e-053117230545560
Pubmed

Crosstalk between CLCb/Dyn1-Mediated Adaptive Clathrin-Mediated Endocytosis and Epidermal Growth Factor Receptor Signaling Increases Metastasis.

EGFR DNM1

3.36e-053117228171750
Pubmed

Phosphorylation of dedicator of cytokinesis 1 (Dock180) at tyrosine residue Y722 by Src family kinases mediates EGFRvIII-driven glioblastoma tumorigenesis.

DOCK1 EGFR

3.36e-053117222323579
Pubmed

Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane.

EGFR DNM1

3.36e-053117222371560
Pubmed

Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.

FMNL2 FMNL1

3.36e-053117212684686
Pubmed

Bone morphogenetic proteins promote development of fetal pancreas epithelial colonies containing insulin-positive cells.

BMP5 BMP6

3.36e-053117211865031
Pubmed

Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone.

BMP5 BMP6

3.36e-05311722263636
Pubmed

Cytosolic PKM2 stabilizes mutant EGFR protein expression through regulating HSP90-EGFR association.

EGFR PKM

3.36e-053117226500058
Pubmed

Bi-modal regulation of a formin by srGAP2.

SRGAP2 FMNL1

3.36e-053117221148482
Pubmed

An Alternative Splicing Program for Mouse Craniofacial Development.

MYO1B ENAH EXOC1

4.72e-0521117333013468
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

KIF21A PCLO MYO1B SMC3 TJP1 ASNS ENAH RBM14 KIF2A

4.96e-05498117936634849
Pubmed

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

NT5E MYO1B TJP1 ASNS UTRN

5.11e-05118117527377895
Pubmed

LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.

PCLO UGGT1 HAUS3 SRGAP2 TUBGCP2 ADGRG4 SBF1 ENAH RBM14 HECTD1

6.26e-056391171023443559
Pubmed

Effects of CD73 on human colorectal cancer cell growth in vivo and in vitro.

NT5E EGFR

6.70e-054117226708311
Pubmed

A Steric-inhibition model for regulation of nucleotide exchange via the Dock180 family of GEFs.

DOCK1 DOCK2

6.70e-054117215723800
Pubmed

The phox homology domain of phospholipase D activates dynamin GTPase activity and accelerates EGFR endocytosis.

EGFR DNM1

6.70e-054117216622417
Pubmed

Combinatorial genetics reveals the Dock1-Rac2 axis as a potential target for the treatment of NPM1;Cohesin mutated AML.

DOCK1 SMC3

6.70e-054117235778533
Pubmed

Endophilin-1 regulates blood-brain barrier permeability by controlling ZO-1 and occludin expression via the EGFR-ERK1/2 pathway.

EGFR TJP1

6.70e-054117224854121
Pubmed

Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

DNAH3 DNAH9

6.70e-054117211175280
Pubmed

Interaction of ATP sensor, cAMP sensor, Ca2+ sensor, and voltage-dependent Ca2+ channel in insulin granule exocytosis.

CACNA1S RAPGEF4

6.70e-054117214660679
Pubmed

Dynamin1 is a novel target for IRSp53 protein and works with mammalian enabled (Mena) protein and Eps8 to regulate filopodial dynamics.

ENAH DNM1

6.70e-054117225031323
Pubmed

Dominant negative Bmp5 mutation reveals key role of BMPs in skeletal response to mechanical stimulation.

BMP5 BMP6

6.70e-054117218380899
Pubmed

A genome-wide association study of monozygotic twin-pairs suggests a locus related to variability of serum high-density lipoprotein cholesterol.

DOCK1 SRGAP2

6.70e-054117223031429
Pubmed

Stabilization of VEGFR2 signaling by cerebral cavernous malformation 3 is critical for vascular development.

KRIT1 EGFR TJP1

7.13e-0524117320371769
Pubmed

Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.

PCLO RAPGEF4 MYO1B KIF2A DNM1

8.39e-05131117528634551
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

TRPM6 DENND4A PCLO UGGT1 MYO1B FASTKD2 DAZAP1 SMC3 ASNS ENAH RBM14 PKM PRMT3 KIF2A SUZ12

8.96e-0514251171530948266
Pubmed

The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.

PPFIA2 PCLO ENAH PKM EXOC1 WDFY1

9.93e-05218117633378226
Pubmed

The Pk-3 gene determines both the heart, M1, and the kidney, M2, pyruvate kinase isozymes in the mouse; and a simple electrophoretic method for separating phosphoglucomutase-3.

BMP5 PKM

1.11e-04511726241468
Pubmed

Histological development and dynamic expression of Bmp2-6 mRNAs in the embryonic and postnatal mouse cranial base.

BMP5 BMP6

1.11e-045117217066377
Pubmed

E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning.

EGFR TJP1

1.11e-045117229093447
Pubmed

Piccolo, a Ca2+ sensor in pancreatic beta-cells. Involvement of cAMP-GEFII.Rim2. Piccolo complex in cAMP-dependent exocytosis.

PCLO RAPGEF4

1.11e-045117212401793
Pubmed

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex.

DOCK1 DOCK2

1.11e-045117212134158
Pubmed

The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo.

DOCK1 DOCK2

1.11e-045117224365888
Pubmed

Effect of bone morphogenetic proteins-4, -5 and -6 on DNA synthesis and expression of bone-related proteins in cultured human periodontal ligament cells.

BMP5 BMP6

1.11e-045117215516325
Pubmed

Non-adherent cell-specific expression of DOCK2, a member of the human CDM-family proteins.

DOCK1 DOCK2

1.11e-045117210559471
Pubmed

Epidermal growth factor receptor-mediated tissue transglutaminase overexpression couples acquired tumor necrosis factor-related apoptosis-inducing ligand resistance and migration through c-FLIP and MMP-9 proteins in lung cancer cells.

TGM2 EGFR

1.11e-045117221525012
Pubmed

Development and maturation of invariant NKT cells in the presence of lysosomal engulfment.

IDUA ARSA

1.11e-045117219637231
Pubmed

Expression of bone morphogenetic proteins in human metastatic prostate and breast cancer.

BMP5 BMP6

1.11e-045117215861517
Pubmed

LRRK2 delays degradative receptor trafficking by impeding late endosomal budding through decreasing Rab7 activity.

LRRK2 EGFR

1.11e-045117225080504
Pubmed

Erythroferrone inhibits the induction of hepcidin by BMP6.

BMP5 BMP6

1.11e-045117230097509
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

MYO1B AP4E1 KMT2C SMC3 EXOC1 DNM1 HECTD1

1.14e-04322117726514267
Pubmed

Tau interactome maps synaptic and mitochondrial processes associated with neurodegeneration.

MAOA PPFIA2 KIF21A FSD1L ENAH RBM14 PKM SV2C DNM1

1.18e-04558117935063084
Pubmed

The ATG5 interactome links clathrin-mediated vesicular trafficking with the autophagosome assembly machinery.

SBF1 ULK1 DNM1 SNX9 UTRN RAB33B

1.33e-04230117635449600
Pubmed

A genetic linkage map of the mouse: current applications and future prospects.

COL9A1 BMP5 BMP6

1.41e-043011738211130
Pubmed

Transgenic mouse proteomics identifies new 14-3-3-associated proteins involved in cytoskeletal rearrangements and cell signaling.

PDE1B PPFIA2 SBF1 ENAH KIF2A

1.44e-04147117516959763
Pubmed

The synaptic vesicle cycle.

PPFIA2 PCLO SV2C

1.56e-0431117315217342
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

PPFIA2 SRGAP2 SMC3 EXOC1 UTRN

1.64e-04151117517043677
Pubmed

Bone morphogenetic protein signaling in the developing kidney: present and future.

BMP5 BMP6

1.67e-046117218331343
Pubmed

Postsynaptic CaV1.1-driven calcium signaling coordinates presynaptic differentiation at the developing neuromuscular junction.

CACNA1S PCLO

1.67e-046117231804576
Pubmed

Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation.

BMP5 BMP6

1.67e-04611729415424
Pubmed

Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis.

EGFR ENAH

1.67e-046117224076656
Pubmed

Mouse profilin 2 regulates endocytosis and competes with SH3 ligand binding to dynamin 1.

ENAH DNM1

1.67e-046117216319076
Pubmed

Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos.

BMP5 BMP6

1.67e-04611729056639
Pubmed

Colocalization of BMP 7 and BMP 2 RNAs suggests that these factors cooperatively mediate tissue interactions during murine development.

BMP5 BMP6

1.67e-04611727605753
Pubmed

Osteocyte control of bone formation via sclerostin, a novel BMP antagonist.

BMP5 BMP6

1.67e-046117214633986
Pubmed

HDAC1 nuclear export induced by pathological conditions is essential for the onset of axonal damage.

KIF2A DNM1

1.67e-046117220037577
Pubmed

Tight Junction Protein 1 Modulates Proteasome Capacity and Proteasome Inhibitor Sensitivity in Multiple Myeloma via EGFR/JAK1/STAT3 Signaling.

EGFR TJP1

1.67e-046117227132469
Pubmed

Morphophenotypic characteristics of intralymphatic cancer and stromal cells susceptible to lymphogenic metastasis.

MSR1 EGFR

1.67e-046117222429811
Pubmed

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.

DOCK1 PCLO TUBGCP2 DAZAP1 EGFR RBM14 CTU1 DYRK2

1.76e-04462117831138677
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

UGGT1 MYO1B ITPR2 DAZAP1 SMC3 TJP1 RBM14 PKM KIF2A HEATR5B SNX9 UTRN

1.79e-0410241171224711643
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

KIF21A MYO1B FASTKD2 RRM2 TGM2 SBF1 SMC3 ASNS RBM14 PKM EXOC1 PRMT3 KIF2A UTRN

1.87e-0413531171429467282
Pubmed

Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex.

CCP110 TJP1 KIF2A

1.88e-0433117330626697
InteractionRAB11A interactions

DENND4A NT5E LRRK2 KRIT1 ITPR2 AP4E1 ZFYVE9 EGFR SMC3 RBM14 SH3BP5L EXOC1 HEATR5B STX10 FMNL1 WDFY1 DOP1A

2.89e-0683011117int:RAB11A
InteractionRAPGEF4 interactions

DOCK1 PCLO RAPGEF4 LRRK2 SRGAP2

8.05e-06501115int:RAPGEF4
InteractionRIMS2 interactions

CACNA1S PCLO RAPGEF4 EGFR

1.39e-05271114int:RIMS2
InteractionPFN1 interactions

DOCK1 PCLO SRGAP2 FMNL2 DAZAP1 TJP1 ENAH KIF2A DNM1 SNX9 HECTD1 FMNL1

2.42e-0550911112int:PFN1
Cytoband1p32.3

ZYG11A ZFYVE9 ACOT11

5.34e-046111831p32.3
CytobandEnsembl 112 genes in cytogenetic band chr7q21

PCLO KRIT1 CROT ASNS

1.19e-031781184chr7q21
Cytoband11p15.4

UBQLNL OR52J3 OR52E2 OR52N2

1.82e-03200118411p15.4
Cytoband5q33.1

IRGM KIF4B

2.04e-032611825q33.1
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND2A DENND4A SBF1 DENND2C

3.98e-0625794504
GeneFamilyCD molecules|5'-nucleotidases

NT5E NT5C1A

3.90e-0477921042
GeneFamilyBone morphogenetic proteins|Astacins

BMP5 BMP6

1.01e-0311792455
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF21A KIF4B KIF2A

1.06e-0346793622
GeneFamilyOlfactory receptors, family 52

OR52J3 OR52E2 OR52N2

1.28e-0349793165
GeneFamilyDyneins, axonemal

DNAH3 DNAH9

2.46e-0317792536
CoexpressionGSE4748_LPS_VS_LPS_AND_CYANOBACTERIUM_LPSLIKE_STIM_DC_3H_DN

DOCK1 UBQLNL ZNF862 RRM2 SLC35F4 DENND2C DHPS HABP2

2.20e-061891178M6494
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

KIF21A PCLO EGFR TJP1 ACOT11 DENND2C ENAH HECTD1

6.38e-08200118897f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KIF21A PCLO EGFR TJP1 ACOT11 DENND2C ENAH HECTD1

6.38e-082001188ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DENND4A FMNL2 TG KMT2C SV2C SNX9 UTRN

8.45e-071931187779276e775cb2492e8dd36436295a536084a6415
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 DENND2A MAOA MYO1B TGM2 BMP6 EGFR

1.07e-062001187032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 DENND2A MAOA MYO1B TGM2 BMP6 EGFR

1.07e-06200118768fce28690246895fd33354b30960ebcc31aa4cc
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 DENND2A MAOA MYO1B TGM2 BMP6 EGFR

1.07e-062001187376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 DENND2A MAOA MYO1B TGM2 BMP6 EGFR

1.07e-0620011877fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 DENND2A MAOA MYO1B TGM2 BMP6 EGFR

1.07e-062001187878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

DOCK1 DENND2A MAOA MYO1B TGM2 BMP6 EGFR

1.07e-0620011877136936d05ab344a560cf159684c881063b5430d
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_GGT8P|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMP5 CPA3 RRM2 BMP6 EGFR SV2C

4.21e-06159118672678dfedc152f524fac14ddb31d4fed1528d52a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMP5 SRGAP2 SLC35F4 ZFHX4 SH3BP5L DNM1

4.21e-0615911869f6607e395bcca9cb1c83199bdbbaaa62a93938d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LAMP5 SRGAP2 SLC35F4 ZFHX4 SH3BP5L DNM1

4.21e-061591186c8b42ebc25ebcc450832096fbffaa5c5f5fe88e7
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A PDE1B MYO1B BTBD3 BMP5 DAAM2

6.84e-061731186d78397e65e997ddb995111a810f0e2a4f67d0765
ToppCellfacs-Heart-LV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A PDE1B MYO1B BTBD3 BMP5 DAAM2

6.84e-0617311863c852ffe22f4a5b632463086b08c669310684e80
ToppCelldroplet-Mammary_Gland-nan-3m-Endothelial-nan|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRGM MYO1B SHQ1 MSR1 TGM2 XXYLT1

6.84e-061731186fbc8ed566ea36c39c258dd6b3823c82f5d6eb17f
ToppCell3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Tuft|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SH2D6 FAT3 MYO1B ITPR2 KCNQ1 GPT2

8.05e-061781186f17c3b7bb562ac24c6a03fe3c9ba94c2b434c141
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FAT3 MYO1B SLC12A8 ITPR2 CROT SV2C

8.05e-061781186ccea3c8908d72f5fecd151a133048c8e9758304c
ToppCellLV-07._Pericyte|World / Chamber and Cluster_Paper

DENND2A PDE1B MYO1B BMP5 DAAM2 UTRN

9.42e-061831186273db6a3b00a93ca852498471187b642b5368185
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL9A1 PPFIA2 FAT3 PCLO ZFHX4 DNAH9

9.72e-0618411862cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL9A1 PPFIA2 FAT3 PCLO ZFHX4 DNAH9

9.72e-061841186ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL9A1 PPFIA2 FAT3 PCLO ZFHX4 DNAH9

9.72e-0618411862b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND2A PPFIA2 MYO1B TJP1 DOCK6 DYRK2

1.00e-051851186a7dba7db79275884b2a93d8a16f2e0c739e71370
ToppCell3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SH2D6 MYO1B ITPR2 KMT2C KCNQ1 SNX9

1.00e-051851186686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

DENND2A MYO1B BMP5 DAAM2 DOCK6 UTRN

1.00e-051851186ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MC3R LAMP5 BMP6 EGFR SV2C UTRN

1.03e-051861186310d16f4e5cffee3ea6d7635508c513a3b92131e
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND2A PPFIA2 MYO1B TJP1 DOCK6 DYRK2

1.07e-051871186a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

FAT3 PCLO LAMP5 SLC35F4 ZFHX4 DNM1

1.17e-0519011866e92c78799f34b31d098854503c796edb0dc7f80
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MC3R LAMP5 BMP6 EGFR SV2C UTRN

1.20e-051911186fa50a3c7ff86e1ee07100da1ace0b0fa1b0ab26b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMP5 SLC35F4 BMP6 EGFR SV2C UTRN

1.27e-051931186294cb5b580bb83fe0eb04f112d5507aac35d4d44
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

DOCK2 SRGAP2 FMNL2 ITPR2 MSR1 SNX9

1.27e-051931186a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMP5 SLC35F4 BMP6 EGFR SV2C UTRN

1.27e-0519311863d3c45d5ff6f3396a1990615aae9fe176e799994
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMP5 SLC35F4 BMP6 EGFR SV2C UTRN

1.31e-05194118652aebb0b563e2c2058e7f0554ae870e47692b163
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMP5 SLC35F4 BMP6 EGFR SV2C UTRN

1.31e-0519411866ac759828c41ffa974ee82842162caa959351dd1
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMP5 SLC35F4 BMP6 EGFR SV2C UTRN

1.31e-0519411865d0b0d8e96f0e0297a4dba70a05d87081a4eb323
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMP5 SLC35F4 BMP6 EGFR SV2C UTRN

1.31e-051941186bd06e2b8d8c06cddf2e4f58849b86e09013acae1
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21A PCLO UGGT1 RAPGEF4 KMT2C PKM

1.35e-0519511863e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21A PCLO UGGT1 RAPGEF4 KMT2C PKM

1.35e-0519511867796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL9A1 FAT3 BMP5 ZFHX4 TJP1 ENAH

1.43e-05197118663b63c6b2f842adb87bc83222ff86796bd9b58f6
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL9A1 FAT3 BMP5 ZFHX4 TJP1 ENAH

1.43e-051971186fb50903b87498b400c8e16e6a561b6d9458e5d97
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

EGFR SMC3 TJP1 KIF2A SUZ12 UTRN

1.47e-05198118676d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

DENND2A KHDC1 ZFHX4 EGFR TJP1 DAAM2

1.52e-051991186a13f4b8a039304e685464cc8879659824cad5a3e
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMP5 BMP6 ZFHX4 EGFR SV2C UTRN

1.56e-052001186862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMP5 BMP6 ZFHX4 EGFR SV2C UTRN

1.56e-052001186a91345f268f13170c27309333603eb82400c9947
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-DBP|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMP5 BMP6 EGFR SV2C DAAM2 UTRN

1.56e-05200118617ee2ca50a3690531d42dab5858c6ff9d103cae0
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAT3 BMP5 ZFHX4 TJP1 ENAH DAAM2

1.56e-0520011863c898e81444b001835c3f1bbc68183078701b135
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-DBP--L1-2|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMP5 BMP6 EGFR SV2C DAAM2 UTRN

1.56e-05200118605440294290b4f5c63342544170645a759227e00
ToppCell10x5'v1-week_17-19-Mesenchymal_osteo|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FAT3 BMP5 ZFHX4 TJP1 ENAH DAAM2

1.56e-0520011863eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

DENND2A PPFIA2 MYO1B DAAM2 DOCK6 DYRK2

1.56e-05200118669edc375d85689300d1dbc1217fedc40063ecdcb
ToppCellNeuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMP5 BMP6 ZFHX4 EGFR SV2C UTRN

1.56e-052001186d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCellNeuronal-Inhibitory-iA-iA_2(LAMP5)-DBP-|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMP5 BMP6 EGFR SV2C DAAM2 UTRN

1.56e-0520011860e7a07a7c6d743d9763315c78f1bc1e1867688d8
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

IFT140 COL9A1 PCLO KHDC1 ZFHX4

2.33e-0512811852cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAPGEF4 ITIH1 EGFR HABP2 GPT2

6.00e-051561185e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Plch2_Dock5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

RAPGEF4 LAMP5 TGM2 EGFR SV2C

6.18e-051571185516903469756c5fabfdf56d7bd59b3bdd7b44e39
ToppCell356C-Fibroblasts-Fibroblast-D-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DOCK2 PCLO RAPGEF4 MSR1 BMP6

6.56e-051591185299e2162a82e31196d7f3a110c2db622349edfff
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT3 LAMP5 MYO1B ZFHX4 FMNL1

6.56e-051591185a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCell356C-Fibroblasts-Fibroblast-D|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DOCK2 PCLO RAPGEF4 MSR1 BMP6

6.56e-0515911850a3a363b30a8c741e1a3e2525725108d03c21776
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cbln4_Fezf2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

FAT3 LAMP5 MYO1B ZFHX4 FMNL1

6.76e-051601185d8241404d775f9a709abdf17988f36293fcf4c58
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL9A1 PPFIA2 FAT3 ZFHX4 DNAH9

6.76e-051601185c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellPND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HAUS3 RRM2 TG PKM FMNL1

6.76e-051601185ec81814f3a475ba9bc049cb793bf93bc0b650d37
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL9A1 PPFIA2 FAT3 ZFHX4 DNAH9

6.76e-05160118525c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell5'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SH2D6 FAT3 PCLO ITPR2 KCNQ1

6.96e-051611185f5df8c6a340d5026726804b103e32137f363ca40
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related-Tuft|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SH2D6 FAT3 MYO1B ITPR2 KMT2C

8.51e-0516811858072d0496b7b730c4601009eaa69ec5366d26d73
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

COL9A1 DENND4A NT5E MYO1B HEATR5B

8.75e-051691185c3a6179a64589a370108fea809b157839347759c
ToppCelldroplet-Marrow-BM-1m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND2A NT5E LRRK2 FMNL2 WDFY1

9.25e-0517111858a0c08f0aa3a80cd6346c81deb242e430ebd897b
ToppCellPND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDE1B KIF21A TGM2 MICU2 CTU1

9.77e-05173118503b50b2376d353748a32bf14a9fc8341ea61dbca
ToppCellPND28-Endothelial-Endothelial_lymphatic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDE1B KIF21A TGM2 MICU2 CTU1

9.77e-0517311852978c744d3c8dcaa2b9bb225abf846f82e8f9176
ToppCellPND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDE1B KIF21A TGM2 MICU2 CTU1

9.77e-05173118512da47b90aecedaa31764ff7ddb853ee39123e9d
ToppCellPND28-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PDE1B KIF21A TGM2 MICU2 CTU1

9.77e-05173118523d4a315a0ad5c6fc77bcfc18b6c1ff55be99e8f
ToppCell5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PDE1B FMNL2 ITPR2 MSR1 FMNL1

1.00e-041741185d5c22b43531414951666ee7542a66ed9380e2d14
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF21A RAPGEF4 ITIH1 EGFR ULK1

1.03e-0417511855c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1S HAUS3 TG ASNS GPT2

1.03e-04175118528b29f844fa46fe579ddc19039fb2d9dc5f48f3b
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1S HAUS3 TG ASNS GPT2

1.03e-041751185ac96ca9ca309b0d72a2f5af6a3b02c7f80755750
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FAT3 LRRK2 SLC35F4 EGFR UTRN

1.06e-041761185327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellP15-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

DENND2A LAMP5 ARMC2 BMP6 GPT2

1.06e-041761185792f414f5092aba14260b8e16378e793a822498e
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZYG11A SH2D6 RRM2 BMP6 GPT2

1.09e-041771185d2c1f46913ac00bbc0bb9320d5652edc01b34179
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-plasmablast|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

ZYG11A SH2D6 RRM2 BMP6 GPT2

1.09e-04177118565e090aad0ffb737ce034e25bd5b12a0b1dd9684
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

DENND2A MYO1B TJP1 DAAM2 DOCK6

1.12e-041781185185b44700f06ec58b3c09c80520502166c965fd6
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DENND4A MSR1 BMP5 CFAP70 HEATR5B

1.15e-04179118587f608b137aae34572b150492a83a3a127cff40b
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMNL2 BTBD3 EGFR SNX9 RAB33B

1.18e-041801185df60970520fba2ac0639faa54096766d07418ca4
ToppCellLA-07._Pericyte|World / Chamber and Cluster_Paper

DENND2A MYO1B BMP5 DAAM2 UTRN

1.27e-041831185e3835db4795362b0442d5893baf2a78efcc20428
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL9A1 FAT3 FMNL2 DAAM2 DNM1

1.27e-0418311857eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO1B ZFYVE9 EGFR TJP1 UTRN

1.30e-04184118557c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellCOVID-19-Endothelial_cells-Arterial_endothelial_cells|COVID-19 / group, cell type (main and fine annotations)

RAPGEF4 TGM2 TJP1 SV2C DOCK6

1.30e-0418411850f19494789f38ab1a420545e15e748ca7eb345c3
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

MYO1B ZFYVE9 EGFR TJP1 UTRN

1.30e-041841185d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DENND2A COL9A1 FMNL2 ZFHX4 DAAM2

1.34e-0418511856712512100ccef456d2e2bd201d0987986c92ac9
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LRRK2 BTBD3 ITPR2 SLC35F4 UTRN

1.34e-0418511855a0340c25196453f19e424d346efbf66d2c53ac3
ToppCellLV-07._Pericyte|LV / Chamber and Cluster_Paper

DENND2A MYO1B BMP5 DAAM2 UTRN

1.34e-041851185acb38eba871ec72f2a8136a33b87d33b8c85465d
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

PPFIA2 PCLO LRRK2 KMT2C DAAM2

1.37e-04186118523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DENND2A MYO1B DAAM2 DOCK6 UTRN

1.37e-041861185888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellRV-07._Pericyte|RV / Chamber and Cluster_Paper

DENND2A MYO1B BMP5 DAAM2 UTRN

1.37e-041861185c533b264fbe12bc35467486fc7fbde24ba968fe1
ToppCellRV-07._Pericyte|World / Chamber and Cluster_Paper

DENND2A MYO1B BMP5 DAAM2 UTRN

1.41e-041871185dc274d6bbda619a2c914d84e2b4069cfef1739d1
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYO1B SLC35F4 BMP6 ENAH PKM

1.41e-0418711857e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM6 DENND2A PPFIA2 SNX9 HECTD1

1.41e-04187118577886f99c229610abd28c4c370d2c7d1536c9782
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

DENND2A PPFIA2 FAT3 BMP5 DAAM2

1.41e-041871185bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MC3R LAMP5 BMP6 EGFR SV2C

1.44e-0418811850501a8aa850bd2e347020abd1cac4d8075738189
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MC3R LAMP5 BMP6 EGFR SV2C

1.44e-041881185433a25fe52914e07e7ba695881f9bcca2d9467ff
ToppCell10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NT5E BMP5 EGFR ENAH DOCK6

1.44e-041881185ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DENND2A MYO1B TJP1 DAAM2 DOCK6

1.44e-041881185ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMP5 BMP6 EGFR SV2C UTRN

1.48e-041891185f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-4_LAMP5_DUSP4_(Lamp5_Rosehip)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMP5 SLC35F4 BMP6 EGFR SV2C

1.48e-041891185979b7fa947538aa7ca4a219263da2575869a2caa
ComputationalGenes in the cancer module 59.

PPFIA2 RAPGEF4 ITPR2 BMP6

2.58e-0527704MODULE_59
DrugNiclosamide [50-65-7]; Down 200; 12.2uM; PC3; HG-U133A

MAOA PCLO CROT RBM12 ZFYVE9 RBM14 DOP1A DYRK2

5.45e-0618611781916_DN
DrugNorfloxacin [70458-96-7]; Down 200; 12.6uM; MCF7; HT_HG-U133A

MAOA NT5E SLC12A8 TUBGCP2 ITPR2 AP4E1 EGFR ACOT11

8.30e-0619711782253_DN
DrugMetoclopramide monohydrochloride [7232-21-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A

PCLO TUBGCP2 IDUA TGM2 BMP5 SBF1 DOCK6 UTRN

8.62e-0619811784750_DN
DiseaseMoyamoya disease

DOCK1 RAPGEF4 FMNL2

4.75e-04401123MONDO_0016820
DiseaseUnipolar Depression

MAOA PCLO ITIH1 TG ARSA EGFR

4.75e-042591126C0041696
DiseaseGlioblastoma Multiforme

TGM2 EGFR SUZ12 DYRK2

8.62e-041111124C1621958
Diseasepeptic esophagitis (biomarker_via_orthology)

EGFR TJP1

9.19e-04121122DOID:13976 (biomarker_via_orthology)
Diseasehypothyroidism (implicated_via_orthology)

TG ARSA

1.08e-03131122DOID:1459 (implicated_via_orthology)
Diseaseobesity (implicated_via_orthology)

MC3R ITPR2 BMP5 BMP6 ZFHX4

1.40e-032151125DOID:9970 (implicated_via_orthology)
DiseaseDown syndrome (implicated_via_orthology)

DOP1A DYRK2

1.45e-03151122DOID:14250 (implicated_via_orthology)
Diseasequinate measurement

LRRK2 KCNQ1

1.45e-03151122EFO_0021167
DiseaseMajor Depressive Disorder

MAOA PCLO ITIH1 ARSA EGFR

2.39e-032431125C1269683
DiseaseBRCAX breast cancer

DOCK1 ITPR2

2.59e-03201122EFO_0009443
DiseaseGlioblastoma

TGM2 EGFR SUZ12

3.41e-03791123C0017636
DiseaseIntrahepatic Cholangiocarcinoma

KMT2C EGFR

3.73e-03241122C0345905
DiseaseExtrahepatic Cholangiocarcinoma

KMT2C EGFR

3.73e-03241122C3805278

Protein segments in the cluster

PeptideGeneStartEntry
AVEAAQAHQMAPDMF

GPT2

451

Q8TD30
HQVDDAMMANAAQKF

ASNS

491

P08243
FFDDQMFHVAGAQEM

NT5C1A

326

Q9BXI3
VSMHNAAREMVFVAE

SH3BP5L

141

Q7L8J4
MARMLQDVFETHFSK

BRDT

361

Q58F21
EMTEMFNFNHTYVAH

ADGRG4

926

Q8IZF6
NALMFNNELMADVHF

BTBD6

126

Q96KE9
DFIVQNNVHRFMMAL

ARMC2

711

Q8NEN0
FMMALLDAQHQDICF

ARMC2

721

Q8NEN0
FHMEMVVHVDAAQAF

ACOT11

426

Q8WXI4
AMMFNNDLMADVHFV

BTBD3

111

Q9Y2F9
MDPSFFQMDASCVNH

DOP1A

2116

Q5JWR5
SVDQAVNMHFHDIMG

DAZAP1

166

Q96EP5
MMDTHSAQLEFSVNL

AP4E1

1011

Q9UPM8
HMIDLEIQEAFLFFM

DENND4A

556

Q7Z401
MPFSAMENDVRDFFH

RBM12

311

Q9NTZ6
CAVMKQFAFVHMREN

RBM14

31

Q96PK6
NVHAVVFVYDMTNMA

RAB33B

106

Q9H082
SDTFVNNMVMHFAAV

OR7A2P

191

Q8NGA2
ASLEHQFSPMMQAEF

ITPR2

1611

Q14571
MENQEKASIAGHMFD

MAOA

1

P21397
FDMVHIDTKSASQMF

DAAM2

346

Q86T65
TQMFFIHNFTLMESA

OR52E2

101

Q8NGJ4
CMMQLFAEHFFAGVE

OR4C15

96

Q8NGM1
MPHFMRTNSFAEDLD

KCNQ1

476

P51787
MFRMDNDHVIDATLT

KMT2C

4826

Q8NEZ4
GHNVDFNFLEVMSME

ITIH1

436

P19827
MHLMINNTKEFIFSE

DNM1

686

Q05193
SDNMTHLMVDFSQER

FSD1L

171

Q9BXM9
EAVQAEFASHGMQNM

ASAH2

551

Q9NR71
AQFSMNHVMLAKTAE

IRGM

121

A1A4Y4
RDIAFIMDDFQHAMS

PCLO

4416

Q9Y6V0
MAQLFMDHLFAGAEV

OR4A15

126

Q8NGL6
HISSVFRLMQDDEMN

PDE1B

296

Q01064
CNTMFGSQHQMDVAF

PDXDC2P

206

Q6P474
ESDIFMLIFDAMHSF

LRRK2

156

Q5S007
MLIFDAMHSFPANDE

LRRK2

161

Q5S007
FDLVIFHQMSSNIME

LRRK2

671

Q5S007
QQLHAAMADTFLEHM

PKM

16

P14618
FHTMAQIMAEQEVEN

LAMP5

21

Q9UJQ1
CFQIHSMENKMSFIV

KRIT1

696

O00522
LMDQGDFFVHFMDLA

TUBGCP2

521

Q9BSJ2
YMAFAHDLMADAQRQ

ARSA

201

P15289
FNACLAQMFFVHMLT

OR52N2

96

Q8NGI0
SHEEPAFQNFMQESM

GPN1

351

Q9HCN4
LMQDFHMVESIFFPS

PIPSL

56

A2A3N6
EEMRFQEVFMEHMSN

MSR1

106

P21757
MEANLMDTEHFQNFS

MSR1

131

P21757
MDTEHFQNFSMTTDQ

MSR1

136

P21757
VLDHQQFDFVVRMMN

SBF1

616

O95248
QLFTFHEAVSQMVEM

KIF2A

606

O00139
HLLLQENYNMFMEDA

HABP2

221

Q14520
DFLSNMSMDFQNHLG

EGFR

171

P00533
DFCMHTGIQKQMEAF

HECTD1

2451

Q9ULT8
IRMAFMAATDHSNQL

HEATR5B

1296

Q9P2D3
ATHHVAANMMVDFRV

CPA3

56

P15088
MQCEFHSTRSFQMFE

DOCK1

1111

Q14185
DTLDALFNIMMEHSQ

DOCK2

651

Q92608
TFAEQVQDLMFNLHM

DOCK6

1546

Q96HP0
DVFFRNLIMGMDDNH

DNAH3

1976

Q8TD57
SLRHFLEVFMETQMF

DENND2A

941

Q9ULE3
MKQFAQDFVMHTDVR

PRMT3

186

O60678
VHSDFHFDNVLSAMM

CACNA1S

991

Q13698
HFDNVLSAMMSLFTV

CACNA1S

996

Q13698
MEMAFHEASKQLQAR

CFAP70

756

Q5T0N1
VAETFAQKMDAFMHE

DHPS

351

P49366
HNADDMAETVLMNFL

CTU1

171

Q7Z7A3
TNQLDMLFAVEMHSS

FAT3

3696

Q8TDW7
SAFLNDADMVMSFVN

BMP6

206

P22004
DEVTQLMMFFRHSNL

HAUS3

171

Q68CZ6
HDIFFVMDAAERMSI

CCP110

871

O43303
VRHFLDLFMETQMFA

DENND2C

861

Q68D51
HDTNFLNDADMVMSF

BMP5

146

P22003
FMVASMQFINIVVHS

FMNL2

316

Q96PY5
HDFDNVSMTMQGFLN

IDUA

186

P35475
LDVANMVAMLHTAAN

GPR142

396

Q7Z601
QFIQHMDNIFDSMIC

MC3R

111

P41968
DFMVACMQFINIVVH

FMNL1

321

O95466
ADMQKMLFEEQNHFS

KIF4B

896

Q2VIQ3
QNFHAPMVFHMEEDQ

KHDC1

91

Q4VXA5
CMRVIQEHFAEMAAS

COL9A1

766

P20849
DVVMMENFHHIFATL

EXOC1

726

Q9NV70
DANVFASAMMHALEV

ENAH

96

Q8N8S7
MTSHMENLQNALYFD

DNAH9

4286

Q9NYC9
MTQMSQVQELFHEAA

SLC12A8

1

A0AV02
HMLENFTFRNHICMT

DYRK2

286

Q92630
ERAMSSHFHQQVAAM

IFT140

406

Q96RY7
DSDSHFEQLMVNMLD

PPFIA2

26

O75334
TFCAFHDMIQLMNST

CROT

596

Q9UKG9
AQMFLIHAFTGMEAE

OR52J3

101

Q8NH60
KDQFATHEAFMMELT

UTRN

346

P46939
TDSVLNDFIMMHCVF

RAPGEF4

526

Q8WZA2
VSIMSYALQAEMNHF

SNX9

541

Q9Y5X1
VMVEHFFRQGMLDVA

RMND5A

121

Q9H871
AVSDMIMELAVHAQF

SMC3

1156

Q9UQE7
FTINFTMENQIHTGM

SV2C

481

Q496J9
SVLNSQHMFEVLAAM

FASTKD2

341

Q9NYY8
THLEDFAIAMQMFSL

MICU2

326

Q8IYU8
EELFSSVAAMVQHFM

SH2D6

136

Q7Z4S9
MMAFLEKSQEQENHA

SHQ1

226

Q6PI26
IVMMAYADNFHADSI

SLC35F4

316

A4IF30
MIIFQDLISHNEMFS

TPT1P8

1

Q9HAU6
DAMINNNLRHTDEMF

NT5E

366

P21589
QSMNMGSDFDVFAHI

TGM2

481

P21980
MMFTDEDAAVNHQKS

ZFHX4

3361

Q86UP3
AEMSHVPQSQDFQFM

TRPM6

766

Q9BX84
FLDNMFHVLMAQVTT

SLC35A5

326

Q9BS91
FYGFQIAMENIHSEM

RRM2

161

P31350
ESINDMFHENAMLQT

KIF21A

416

Q7Z4S6
QGIMLDAFAQEMDHT

STX10

191

O60499
FIADNQMNHACMLFV

SUZ12

626

Q15022
AFLNHLSQFSEENMM

SRGAP2

621

O75044
AHFQCQMDQLVLVFM

UBQLNL

61

Q8IYU4
EISSDLMANMEHFFN

ZNF862

546

O60290
AMVNGVSMDNVEHAF

TJP1

76

Q07157
FVNTTDMMIFDLVHS

TG

196

P01266
ASILDDFRMHFMNYQ

ZYG11A

736

Q6WRX3
AVMEFHVSEDFNKMN

WDFY1

91

Q8IWB7
QMVQSAALDEMFQHR

ULK1

986

O75385
FLNMTEHFSESQDMT

ZFYVE9

386

O95405
AELMNTAEMFLSNHI

UGGT1

511

Q9NYU2
SDSIFFLSVAMHQIM

XXYLT1

201

Q8NBI6
AFITHFNQEMADMIA

LDAH

301

Q9H6V9
NAMQIVGFMDHEAES

MYO1B

256

O43795