Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

SETX DDX31 SPAST TCP1 ATP13A1 DDX52 MYO19 SMCHD1 PEX6 ATP10A ORC1 MLH3 UBA6 ACIN1 ACSBG2 MTREX DYNC1H1

2.90e-0661414717GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

DDX31 SPAST TCP1 ATP13A1 DDX52 MYO19 SMCHD1 PEX6 ATP10A ORC1 MLH3 ACIN1 MTREX DYNC1H1

4.92e-0644114714GO:0016887
GeneOntologyMolecularFunctionpyrophosphatase activity

PRUNE2 DDX31 SPAST TCP1 ATP13A1 DDX52 MYO19 SMCHD1 PEX6 ATP10A EFTUD2 ORC1 MLH3 RGS6 ACIN1 MTREX DYNC1H1

1.52e-0483914717GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

PRUNE2 DDX31 SPAST TCP1 ATP13A1 DDX52 MYO19 SMCHD1 PEX6 ATP10A EFTUD2 ORC1 MLH3 RGS6 ACIN1 MTREX DYNC1H1

1.54e-0484014717GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

PRUNE2 DDX31 SPAST TCP1 ATP13A1 DDX52 MYO19 SMCHD1 PEX6 ATP10A EFTUD2 ORC1 MLH3 RGS6 ACIN1 MTREX DYNC1H1

1.54e-0484014717GO:0016818
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DDX31 SPAST TCP1 ATP13A1 DDX52 MYO19 SMCHD1 PEX6 ATP10A EFTUD2 ORC1 MLH3 RGS6 ACIN1 MTREX DYNC1H1

1.94e-0477514716GO:0017111
GeneOntologyMolecularFunctionRNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity

NANOGP8 NANOG

3.20e-0441472GO:0001010
GeneOntologyBiologicalProcessmulticellular organismal reproductive process

MYCN CYP1B1 DMXL2 GARIN1A SETX WDR33 SMCHD1 SPEF2 ASH1L TSSK2 APOB DZIP1 NME8 SPATA31D4 FSIP2 SPATA31D3 NLRP14 MLH3 THRA THRB SBF1 BRCA2 ASPM ACSBG2 HERC2

7.56e-07119414425GO:0048609
GeneOntologyBiologicalProcesssexual reproduction

MYCN DMXL2 GARIN1A SETX CENPC TCP1 WDR33 SMCHD1 SPEF2 ASH1L TSSK2 APOB DZIP1 ADCY3 NME8 SPATA31D4 FSIP2 SPATA31D3 NLRP14 MLH3 SBF1 BRCA2 CCNE2 ASPM ACSBG2 HERC2

1.24e-06131214426GO:0019953
GeneOntologyBiologicalProcessmale gamete generation

DMXL2 GARIN1A SETX WDR33 SPEF2 TSSK2 APOB DZIP1 NME8 SPATA31D4 FSIP2 SPATA31D3 NLRP14 MLH3 SBF1 BRCA2 ASPM ACSBG2 HERC2

1.54e-0676214419GO:0048232
GeneOntologyBiologicalProcessspermatogenesis

DMXL2 GARIN1A SETX WDR33 SPEF2 TSSK2 APOB DZIP1 NME8 SPATA31D4 FSIP2 SPATA31D3 NLRP14 SBF1 BRCA2 ASPM ACSBG2 HERC2

4.52e-0674414418GO:0007283
GeneOntologyBiologicalProcessgamete generation

MYCN DMXL2 GARIN1A SETX WDR33 SMCHD1 SPEF2 TSSK2 APOB DZIP1 NME8 SPATA31D4 FSIP2 SPATA31D3 NLRP14 MLH3 SBF1 BRCA2 ASPM ACSBG2 HERC2

4.70e-0698214421GO:0007276
GeneOntologyBiologicalProcessdevelopmental process involved in reproduction

MYCN CYP1B1 DMXL2 GARIN1A SETX WDR33 SMCHD1 SPEF2 ASH1L TSSK2 APOB DZIP1 NME8 SPATA31D4 FSIP2 SPATA31D3 NLRP14 SBF1 BRCA2 ASPM ACSBG2 HERC2

4.66e-05123514422GO:0003006
GeneOntologyBiologicalProcessfemale courtship behavior

THRA THRB

1.45e-0431442GO:0008050
GeneOntologyBiologicalProcesspositive regulation of thyroid hormone receptor signaling pathway

THRA THRB

1.45e-0431442GO:0002157
GeneOntologyCellularComponentnuclear body

SETD1A ZC3H14 SETX CENPC INPPL1 DZIP1 BOLA3 NME8 EFTUD2 PPP4R3B UBE2O THRB SBF1 SUGP2 ACIN1 PRPF19 MTREX MTDH

6.04e-0590314618GO:0016604
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SEH1L SETD1A SETX CENPC ACAT1 TCP1 MAP4K3 DDX52 MYO19 SMCHD1 RIOK3 HEATR1 ANKHD1 EFTUD2 ORC1 RIF1 SAFB SBF1 SUGP2 HNRNPUL2 ANLN LTN1 ASPM ACIN1 ANKRD17 PRPF19 PUM3 PRR14L HERC2 MTREX DYNC1H1

1.11e-1413531473129467282
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SETD1A SETX SPAST SMCHD1 HECTD4 DZIP1 ANKHD1 TBC1D24 VANGL2 PPP4R3B UBE2O SBF1 ZNF532 ZNF592 ANKRD17 RPRD2 MTREX DAGLA IGSF3

1.28e-125291471914621295
Pubmed

MYC multimers shield stalled replication forks from RNA polymerase.

SEH1L ZC3H14 TMA16 DDX31 AKAP8 CENPC ACAT1 TCP1 OGFR DDX52 SMCHD1 HEATR1 EFTUD2 ORC1 RIF1 SAFB SUGP2 ZNF592 ANLN ACIN1 PRPF19 PUM3 MTREX PCCB

4.93e-129891472436424410
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

ZC3H14 DDX31 ACAT1 DDX52 SMCHD1 HEATR1 ANKHD1 RIF1 UBE2O SBF1 SUGP2 ACIN1 ANKRD17 PUM3 HERC2 MTREX DYNC1H1

2.85e-096531471722586326
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SEH1L SETD1A DDX31 AKAP8 HECTD4 PPP4R3B SBF1 HNRNPUL2 ZNF592 ANKRD17 PUM3 RPRD2 HERC2 MTREX

6.33e-094401471434244565
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

ZC3H14 AKAP8 ACAT1 TCP1 DDX52 SMCHD1 HEATR1 EFTUD2 RIF1 SAFB SUGP2 HNRNPUL2 UBA6 ACIN1 PRPF19 PUM3 HERC2 MTREX MTDH DYNC1H1

1.38e-0810241472024711643
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

TMA16 SETX DDX31 AKAP8 TCP1 ATP13A1 WDR33 DDX52 SMCHD1 COBLL1 APOB ANKHD1 FMNL2 RIF1 SUGP2 ACIN1 ANKRD17 PRPF19 PUM3 HERC2 MTREX MTDH DYNC1H1

1.73e-0813711472336244648
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

ZC3H14 DDX31 AKAP8 DDX52 SMCHD1 TRAIP HEATR1 RIF1 SUGP2 HNRNPUL2 ASPM ACIN1 PRPF19 PUM3 HERC2 MTREX MTDH

2.59e-087591471735915203
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

ZC3H14 AKAP8 ACAT1 MPDZ EFTUD2 SAFB SUGP2 HNRNPUL2 ACIN1 MTREX MTDH

2.73e-082741471134244482
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

SEH1L DMXL2 SORBS2 TMA16 SETX AKAP8 WDR33 HECTD4 GTF2IRD1 EFTUD2 VANGL2 SAFB SBF1 SUGP2 ZNF532 HNRNPUL2 ACIN1 PRPF19 MTDH DYNC1H1

3.41e-0810821472038697112
Pubmed

The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.

ZC3H14 DDX31 AKAP8 TCP1 WDR33 DDX52 HEATR1 ANKHD1 EFTUD2 UBE2O SAFB SUGP2 HNRNPUL2 ACIN1 PUM3 MTDH DYNC1H1

6.26e-088071471722681889
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

CYP1B1 ZC3H14 TMA16 SETX DDX31 AKAP8 GTPBP6 ATP13A1 DDX52 MPDZ HEATR1 ANKHD1 ORC1 RIF1 SBF1 ZNF592 ANLN LTN1 ANKRD17 PUM3 REEP4 HERC2 MTREX

8.51e-0814971472331527615
Pubmed

KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4.

ZC3H14 AKAP8 WDR33 SAFB SUGP2 ACIN1 PRPF19 RPRD2

8.84e-08130147835545047
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

SETD1A ZC3H14 TCP1 WDR33 SMCHD1 MPDZ HEATR1 ANKHD1 UBE2O SUGP2 ANLN ACIN1 RPRD2 DYNC1H1

9.90e-085491471438280479
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

SEH1L ZC3H14 DDX31 AKAP8 DDX52 HEATR1 EFTUD2 RIF1 SAFB SUGP2 ZNF592 ACIN1 ANKRD17 PRPF19 PUM3 MTREX MTDH

1.25e-078471471735850772
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

ZC3H14 SETX CENPC ACAT1 WDR33 SMCHD1 HEATR1 EFTUD2 RIF1 SAFB SUGP2 BRCA2 ANLN ACIN1 PRPF19 PUM3 RPRD2 MTDH

1.29e-079541471836373674
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SORBS2 SETX SPAST AKAP8 KIAA0232 INPPL1 COBLL1 TSSK2 MPDZ DZIP1 FSIP2 SBF1 ANLN ANKRD17 REEP4 MTREX FAM110B

1.57e-078611471736931259
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

BIRC8 SETX MAP4K3 DDX52 ASH1L APOB HEATR1 ANKHD1 ADCY3 ZNF568 ANLN SBF2 LTN1 GRAMD2B ACIN1 ANKRD17 CEP295 TSTD2 MTDH

1.75e-0710841471911544199
Pubmed

Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

SETX SMCHD1 HECTD4 MFAP3L ACIN1 ANKRD17 DAGLA

2.76e-0710214779734811
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

AKAP8 TCP1 WDR33 DDX52 HEATR1 ANKHD1 NBAS SUGP2 ANLN PSMG1 LTN1 ANKRD17 PUM3 MTREX DYNC1H1

3.40e-077041471529955894
Pubmed

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

ZC3H14 AKAP8 ACAT1 TCP1 DDX52 HEATR1 ANKHD1 EFTUD2 SAFB SUGP2 HNRNPUL2 PRPF19 PUM3 MTREX DYNC1H1

4.06e-077141471528302793
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

SEH1L ZC3H14 TMA16 SETX AKAP8 WDR33 DDX52 SMCHD1 HEATR1 GTF2IRD1 EFTUD2 ORC1 RIF1 SAFB ACIN1 PRPF19 RPRD2 REEP4 MTREX MTDH

5.91e-0712941472030804502
Pubmed

Human transcription factor protein interaction networks.

SETD1A DDX31 AKAP8 TCP1 PHF23 WDR33 DDX52 SMCHD1 ANKHD1 RIF1 UBE2O SUGP2 HNRNPUL2 ZNF592 ANKRD17 PRPF19 PUM3 RPRD2 HERC2 PCCB DYNC1H1

6.79e-0714291472135140242
Pubmed

Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.

AKAP8 EFTUD2 RIF1 SAFB SUGP2 HNRNPUL2 ACIN1 PRPF19 MTREX

1.05e-06244147929884807
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SETD1A GTPBP6 ATP13A1 INPPL1 HECTD4 PEX6 GTF2IRD1 ANKHD1 C2CD2 TBC1D24 ORC1 SBF1 SUGP2 ZNF592 SBF2 HERC2 DYNC1H1 IGSF3

1.08e-0611051471835748872
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

SEH1L SETX AKAP8 TCP1 WDR33 SMCHD1 EFTUD2 RIF1 ANLN ACIN1 PRPF19 MTREX DYNC1H1

1.27e-065821471320467437
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

SEH1L DMXL2 DDX31 AKAP8 CENPC ATP13A1 MPDZ EXT2 HEATR1 DZIP1 EFTUD2 VANGL2 NBAS UBE2O SBF1 ASPM UBA6 PRPF19 REEP4 HERC2 MTDH

1.28e-0614871472133957083
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

ZC3H14 CENPC ACAT1 TCP1 PHF23 SMCHD1 PPP4R3B RIF1 SAFB SUGP2 ZNF532 HNRNPUL2 ZNF592 PSMG1 UBA6 ACIN1 MTREX

1.50e-0610141471732416067
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

ZC3H14 TMA16 AKAP8 TCP1 DDX52 SMCHD1 CD109 HEATR1 EFTUD2 SAFB HNRNPUL2 ANLN ACIN1 ANKRD17 PRPF19 PUM3 MTREX MTDH DYNC1H1

1.61e-0612571471936526897
Pubmed

MYC Protein Interactome Profiling Reveals Functionally Distinct Regions that Cooperate to Drive Tumorigenesis.

AKAP8 CENPC DDX52 TFDP3 EFTUD2 SUGP2 ANLN PRPF19 RPRD2 MTREX

1.98e-063391471030415952
Pubmed

RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.

ZC3H14 TMA16 DDX31 AKAP8 WDR33 DDX52 EFTUD2 SAFB HNRNPUL2 LTN1 ACIN1 PRPF19 MTREX MTDH

2.22e-067131471429802200
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

DMXL2 SORBS2 SPAST GTPBP6 ATP13A1 ASH1L HECTD4 DZIP1 FMNL2 PPP4R3B UBE2O ZNF532 ZNF592 PSMG1 KCNJ6 HERC2 CADPS2 PCCB DYNC1H1

2.22e-0612851471935914814
Pubmed

DBIRD complex integrates alternative mRNA splicing with RNA polymerase II transcript elongation.

AKAP8 WDR33 SAFB SUGP2 ACIN1 PRPF19

2.24e-0689147622446626
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

ZC3H14 TCP1 SMCHD1 HEATR1 ANKHD1 EFTUD2 RIF1 UBE2O SAFB SUGP2 ACIN1 ANKRD17 PRPF19 RPRD2 PRR14L MTDH

2.36e-069341471633916271
Pubmed

TRIM28-mediated nucleocapsid protein SUMOylation enhances SARS-CoV-2 virulence.

TCP1 DDX52 HEATR1 EFTUD2 SAFB SUGP2 HNRNPUL2 ACIN1 PRPF19 PUM3 MTDH

2.39e-064301471138172120
Pubmed

The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells.

NANOGP8 NANOG RIF1

2.56e-067147316518401
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

ACAT1 TCP1 ATP13A1 DDX52 SMCHD1 APOB HEATR1 ANKHD1 EFTUD2 RIF1 UBE2O SAFB HNRNPUL2 UBA6 ACIN1 PRPF19 PUM3 MTREX MTDH DYNC1H1

2.58e-0614251472030948266
Pubmed

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency.

NANOGP8 NANOG BRCA2 MTREX

4.98e-0627147423395962
Pubmed

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

TMA16 ACAT1 TCP1 WDR33 DDX52 EFTUD2 SUGP2 HNRNPUL2 PRPF19 MTREX MTDH

5.45e-064691471137314180
Pubmed

Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PRUNE2 SETD1A ZNF518A SUGP2 HERC2 DYNC1H1

5.55e-0610414769205841
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

MYCN SORBS2 AKAP8 TBC1D2 GTF2IRD1 EFTUD2 RIF1 SAFB SUGP2 ZNF592 ANLN ACIN1 ANKRD17 PRG4

5.67e-067741471415302935
Pubmed

Functional proteomic analysis of human nucleolus.

DDX31 DDX52 HEATR1 PRPF19 PUM3 MTREX

6.20e-06106147612429849
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

AKAP8 DDX52 EFTUD2 SAFB SUGP2 HNRNPUL2 ZNF592 ACIN1 PRPF19 PUM3 MTREX MTDH

1.10e-056051471228977666
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

TMA16 SETX DDX31 CENPC SMCHD1 FSIP2 RIF1 UBE2O ZNF592 ANLN PUM3 HERC2

1.15e-056081471236089195
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

SETD1A DDX31 ACAT1 TCP1 DDX52 SMCHD1 HEATR1 EFTUD2 PPP4R3B SAFB HNRNPUL2 ACIN1 PRPF19 AMMECR1 MTREX PCCB MTDH DYNC1H1

1.23e-0513181471830463901
Pubmed

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

WDR33 DDX52 HEATR1 ADARB2 EFTUD2 SAFB SUGP2 HNRNPUL2 ACIN1 PRPF19 PUM3 MTREX MTDH

1.48e-057311471329298432
Pubmed

SNIP1 Recruits TET2 to Regulate c-MYC Target Genes and Cellular DNA Damage Response.

ATP13A1 HEATR1 EFTUD2 SUGP2 HNRNPUL2 ACIN1 PRPF19 PUM3

1.55e-05259147830404004
Pubmed

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.

AKAP8 DDX52 RIF1 SUGP2 BRCA2 DYNC1H1

1.60e-05125147621654808
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

SEH1L AKAP8 SMCHD1 CD109 MPDZ EXT2 HEATR1 ANKHD1 VANGL2 UBE2O SBF1 HNRNPUL2 LTN1 ANKRD17 MTDH

1.75e-059741471528675297
Pubmed

Neurodevelopmental control by thyroid hormone receptors.

THRA THRB

1.77e-052147211861164
Pubmed

Fundamentally distinct roles of thyroid hormone receptor isoforms in a thyrotroph cell line are due to differential DNA binding.

THRA THRB

1.77e-052147222570333
Pubmed

Divergent roles for thyroid hormone receptor beta isoforms in the endocrine axis and auditory system.

THRA THRB

1.77e-052147210430610
Pubmed

Audiogenic seizure susceptibility in thyroid hormone receptor beta-deficient mice.

THRA THRB

1.77e-052147211496110
Pubmed

Thyroid hormone receptor-α deletion decreases heart function and exercise performance in apolipoprotein E-deficient mice.

THRA THRB

1.77e-052147226672044
Pubmed

Mutant thyroid hormone receptors (TRs) isolated from distinct cancer types display distinct target gene specificities: a unique regulatory repertoire associated with two renal clear cell carcinomas.

THRA THRB

1.77e-052147221622534
Pubmed

Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation.

THRA THRB

1.77e-052147210346821
Pubmed

Thyroid hormone receptor beta-dependent expression of a potassium conductance in inner hair cells at the onset of hearing.

THRA THRB

1.77e-05214729861043
Pubmed

Comparative Phenotyping of Mice Reveals Canonical and Noncanonical Physiological Functions of TRα and TRβ.

THRA THRB

1.77e-052147238889231
Pubmed

Retardation of cochlear maturation and impaired hair cell function caused by deletion of all known thyroid hormone receptors.

THRA THRB

1.77e-052147211739587
Pubmed

Impaired hair growth and wound healing in mice lacking thyroid hormone receptors.

THRA THRB

1.77e-052147225254665
Pubmed

Interference of a mutant thyroid hormone receptor alpha1 with hepatic glucose metabolism.

THRA THRB

1.77e-052147219282388
Pubmed

Ontogenetic profile of the expression of thyroid hormone receptors in rat and human corpora cavernosa of the penis.

THRA THRB

1.77e-052147220141582
Pubmed

Compensatory role of thyroid hormone receptor (TR) alpha 1 in resistance to thyroid hormone: study in mice with a targeted mutation in the TR beta gene and deficient in TR alpha 1.

THRA THRB

1.77e-052147212750454
Pubmed

Canonical and Noncanonical Contribution of Thyroid Hormone Receptor Isoforms Alpha and Beta to Cardiac Hypertrophy and Heart Rate in Male Mice.

THRA THRB

1.77e-052147238757582
Pubmed

Naturally Occurring Amino Acids in Helix 10 of the Thyroid Hormone Receptor Mediate Isoform-Specific TH Gene Regulation.

THRA THRB

1.77e-052147228911178
Pubmed

Hormone selectivity in thyroid hormone receptors.

THRA THRB

1.77e-052147211222741
Pubmed

Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.

THRA THRB

1.77e-052147216781732
Pubmed

Lack of mutations in the thyroid hormone receptor (TR) alpha and beta genes but frequent hypermethylation of the TRbeta gene in differentiated thyroid tumors.

THRA THRB

1.77e-052147217911173
Pubmed

Effects of thyroid hormone receptor gene disruption on myosin isoform expression in mouse skeletal muscles.

THRA THRB

1.77e-052147210848522
Pubmed

Functional evidence that the self-renewal gene NANOG regulates human tumor development.

NANOGP8 NANOG

1.77e-052147219415763
Pubmed

Increased adipogenesis in bone marrow but decreased bone mineral density in mice devoid of thyroid hormone receptors.

THRA THRB

1.77e-052147215780976
Pubmed

Functional activation of cerebral metabolism in mice with mutated thyroid hormone nuclear receptors.

THRA THRB

1.77e-052147212933686
Pubmed

TRα protects against atherosclerosis in male mice: identification of a novel anti-inflammatory property for TRα in mice.

THRA THRB

1.77e-052147224797634
Pubmed

Suppression of the deafness and thyroid dysfunction in Thrb-null mice by an independent mutation in the Thra thyroid hormone receptor alpha gene.

THRA THRB

1.77e-052147211726557
Pubmed

Functions of thyroid hormone receptors in mice.

THRA THRB

1.77e-052147210691312
Pubmed

Erythroid defects in TRalpha-/- mice.

THRA THRB

1.77e-052147218203951
Pubmed

Establishment of yeast reporter assay systems to detect ligands of thyroid hormone receptors alpha and beta.

THRA THRB

1.77e-052147219853653
Pubmed

New Insights into the Structure and Function of the Thyroid Hormone Receptor.

THRA THRB

1.77e-052147211725045
Pubmed

Thyroid hormone receptor {alpha} modulates lipopolysaccharide-induced changes in peripheral thyroid hormone metabolism.

THRA THRB

1.77e-052147220194731
Pubmed

Expression of peptides and other neurochemical markers in hypothalamus and olfactory bulb of mice devoid of all known thyroid hormone receptors.

THRA THRB

1.77e-052147211113349
Pubmed

Locomotor deficiencies and aberrant development of subtype-specific GABAergic interneurons caused by an unliganded thyroid hormone receptor alpha1.

THRA THRB

1.77e-052147218287507
Pubmed

The two major isoforms of thyroid hormone receptor, TRα1 and TRβ1, preferentially partner with distinct panels of auxiliary proteins.

THRA THRB

1.77e-052147224325866
Pubmed

Retardation of post-natal development caused by a negatively acting thyroid hormone receptor alpha1.

THRA THRB

1.77e-052147212356724
Pubmed

The T3R alpha gene encoding a thyroid hormone receptor is essential for post-natal development and thyroid hormone production.

THRA THRB

1.77e-05214729250685
Pubmed

Differential expression of thyroid hormone receptor isoforms dictates the dominant negative activity of mutant Beta receptor.

THRA THRB

1.77e-052147212198244
Pubmed

Isometric force and endurance in skeletal muscle of mice devoid of all known thyroid hormone receptors.

THRA THRB

1.77e-052147212562961
Pubmed

The c-erb-A gene encodes a thyroid hormone receptor.

THRA THRB

1.77e-05214722879243
Pubmed

Distinct behavioral phenotypes in male mice lacking the thyroid hormone receptor α1 or β isoforms.

THRA THRB

1.77e-052147223567476
Pubmed

Novel non-genomic signaling of thyroid hormone receptors in thyroid carcinogenesis.

THRA THRB

1.77e-052147219549593
Pubmed

Gestational di-(2-ethylhexyl) phthalate exposure causes fetal intrauterine growth restriction through disturbing placental thyroid hormone receptor signaling.

THRA THRB

1.77e-052147229753845
Pubmed

Distinct roles for the Charcot-Marie-Tooth disease-causing endosomal regulators Mtmr5 and Mtmr13 in axon radial sorting and Schwann cell myelination.

SBF1 SBF2

1.77e-052147234718573
Pubmed

Thyroxine-thyroid hormone receptor interactions.

THRA THRB

1.77e-052147215466465
Pubmed

Isometric force and endurance in soleus muscle of thyroid hormone receptor-alpha(1)- or -beta-deficient mice.

THRA THRB

1.77e-052147210712278
Pubmed

Effects of ligand and thyroid hormone receptor isoforms on hepatic gene expression profiles of thyroid hormone receptor knockout mice.

THRA THRB

1.77e-052147212776178
Pubmed

The ability of thyroid hormone receptors to sense t4 as an agonist depends on receptor isoform and on cellular cofactors.

THRA THRB

1.77e-052147224673558
Pubmed

Thyroid hormone receptor Thra and Thrb knockout differentially affects osteoblast biology and thyroid hormone responsiveness in vitro.

THRA THRB

1.77e-052147237992217
Pubmed

Role of thyroid hormone receptor subtypes α and β on gene expression in the cerebral cortex and striatum of postnatal mice.

THRA THRB

1.77e-052147223493375
Pubmed

Regulation of neonatal Sertoli cell development by thyroid hormone receptor alpha1.

THRA THRB

1.77e-052147215858214
Pubmed

Mice lacking thyroid hormone receptor Beta show enhanced apoptosis and delayed liver commitment for proliferation after partial hepatectomy.

THRA THRB

1.77e-052147220090848
Pubmed

Different functions for the thyroid hormone receptors TRalpha and TRbeta in the control of thyroid hormone production and post-natal development.

THRA THRB

1.77e-05214729927422
InteractionSSRP1 interactions

MYCN ZC3H14 SETX AKAP8 NANOG EFTUD2 OVOL2 RIF1 UBE2O SAFB SBF1 SUGP2 BRCA2 HNRNPUL2 ZNF592 ANLN ACIN1 PRPF19 RPRD2 MTDH FMNL1

1.66e-0868514321int:SSRP1
InteractionNUP43 interactions

SEH1L SETD1A SETX DDX31 SPAST CENPC TCP1 ASH1L CCDC168 HEATR1 ZNF518A FSIP2 RIF1 SAFB BRCA2 ZNF532 ZNF592 ACIN1 PCCB

9.71e-0862514319int:NUP43
InteractionSNRNP40 interactions

MYCN SETX DDX31 AKAP8 CENPC TCP1 DDX52 HEATR1 EFTUD2 SUGP2 BRCA2 ZNF532 HNRNPUL2 ANLN ACIN1 PRPF19 MTREX MTDH

6.30e-0763714318int:SNRNP40
InteractionRPS24 interactions

MYCN PRUNE2 DDX31 CENPC DDX52 RIOK3 CCDC168 HEATR1 EFTUD2 UBE2O ANLN PRPF19 PUM3 HERC2 MTDH DYNC1H1

1.15e-0652914316int:RPS24
InteractionSIRT6 interactions

SEH1L SETD1A DDX31 AKAP8 TCP1 KIAA0232 HECTD4 EFTUD2 PPP4R3B SBF1 HNRNPUL2 ZNF592 ANKRD17 PUM3 RPRD2 HERC2 MTREX

2.37e-0662814317int:SIRT6
InteractionMEN1 interactions

SETD1A ZC3H14 DDX31 AKAP8 WDR33 DDX52 NANOG SMCHD1 HEATR1 EFTUD2 RIF1 SAFB SUGP2 BRCA2 ZNF592 ANLN ACIN1 ANKRD17 PRPF19 PUM3 MTREX MTDH

3.51e-06102914322int:MEN1
InteractionSRRM1 interactions

MYCN ZC3H14 OGFR EFTUD2 UBE2O SAFB ANLN ACIN1 PRPF19 HERC2 MTDH DYNC1H1

7.29e-0634814312int:SRRM1
InteractionTOP1 interactions

MYCN ZC3H14 AKAP8 WDR33 TRAIP EFTUD2 UBE2O SAFB BRCA2 HNRNPUL2 ANLN ACIN1 PRPF19 RPRD2 HERC2 MTREX MTDH

9.22e-0669614317int:TOP1
InteractionCIT interactions

ZC3H14 SORBS2 SETX DDX31 ACAT1 TCP1 SMCHD1 CD109 ASH1L APOB HEATR1 EFTUD2 NBAS RIF1 SAFB SUGP2 HNRNPUL2 ANLN ACIN1 PRPF19 PUM3 ACSBG2 PRR14L MTREX MTDH DYNC1H1

1.01e-05145014326int:CIT
InteractionGLDC interactions

ZC3H14 AKAP8 ACAT1 MPDZ EFTUD2 SAFB SUGP2 HNRNPUL2 ACIN1 MTREX MTDH

1.88e-0532114311int:GLDC
InteractionSIRT7 interactions

ZC3H14 DDX31 ACAT1 DDX52 SMCHD1 HEATR1 ANKHD1 RIF1 UBE2O SBF1 SUGP2 ACIN1 ANKRD17 PUM3 HERC2 MTREX DYNC1H1

2.17e-0574414317int:SIRT7
InteractionCPSF6 interactions

MYCN ZC3H14 AKAP8 WDR33 TBC1D2 EFTUD2 SAFB SUGP2 HNRNPUL2 ANLN ACIN1 PRPF19 RPRD2 MTREX

2.34e-0552614314int:CPSF6
InteractionFGF11 interactions

SETD1A AKAP8 TCP1 SMCHD1 ANKHD1 UBE2O ANKRD17 PRPF19

2.94e-051701438int:FGF11
InteractionFRG1 interactions

MYCN EFTUD2 UBE2O ANLN PRPF19 MTREX

3.17e-05851436int:FRG1
InteractionHDLBP interactions

TMA16 SPAST AKAP8 TCP1 ATP13A1 WDR33 SMCHD1 FMNL2 EFTUD2 RIF1 SUGP2 ANLN UBA6 PRPF19 HERC2 MTREX DYNC1H1 IGSF3

3.62e-0585514318int:HDLBP
InteractionMECP2 interactions

MYCN SEH1L DMXL2 SORBS2 TMA16 SETX DDX31 AKAP8 WDR33 HECTD4 GTF2IRD1 EFTUD2 VANGL2 SAFB SBF1 SUGP2 ZNF532 HNRNPUL2 ANLN ACIN1 PRPF19 MTDH DYNC1H1

3.73e-05128714323int:MECP2
InteractionARGLU1 interactions

MYCN ZC3H14 NANOG VANGL2 UBE2O ANLN ACIN1 HERC2

3.77e-051761438int:ARGLU1
InteractionCCND1 interactions

AKAP8 DDX52 TBC1D2 RIF1 THRA THRB SUGP2 BRCA2 TSTD2 DYNC1H1

3.85e-0528614310int:CCND1
InteractionSNRPA interactions

MYCN ZC3H14 AKAP8 WDR33 EFTUD2 SAFB HNRNPUL2 ANLN ACIN1 PRPF19 RPRD2 MTREX DYNC1H1

4.05e-0548214313int:SNRPA
InteractionRBM39 interactions

MYCN ZC3H14 AKAP8 ACAT1 TCP1 DDX52 HEATR1 ANKHD1 EFTUD2 UBE2O SAFB SUGP2 HNRNPUL2 ANLN ACIN1 PRPF19 PUM3 HERC2 MTREX DYNC1H1

4.77e-05104214320int:RBM39
InteractionKRT2 interactions

MYCN KIAA0232 INPPL1 EFTUD2 UBE2O THRB BRCA2 ANLN HERC2

4.86e-052361439int:KRT2
InteractionLURAP1 interactions

SETX GTPBP6 ASH1L MPDZ ZNF518A SBF1 ASPM

5.58e-051371437int:LURAP1
InteractionTMA16 interactions

MYCN TMA16 MAP4K3 UBE2O ANLN HERC2

5.94e-05951436int:TMA16
InteractionSAP18 interactions

MYCN ZC3H14 WDR33 EFTUD2 VANGL2 UBE2O SAFB ANLN LTN1 ACIN1

6.60e-0530514310int:SAP18
InteractionRBBP7 interactions

TCP1 PHF23 NANOG TBC1D2 ASH1L ANKHD1 EFTUD2 UBE2O SAFB BRCA2 HNRNPUL2 ANLN PCCB

6.77e-0550714313int:RBBP7
InteractionOBSL1 interactions

PRUNE2 ZC3H14 TMA16 TCP1 DDX52 SMCHD1 HEATR1 EFTUD2 RIF1 SAFB SUGP2 HNRNPUL2 ACIN1 PRPF19 PUM3 HERC2 MTREX DYNC1H1

7.20e-0590214318int:OBSL1
InteractionEED interactions

MYCN SETX CENPC TCP1 DDX52 NANOG MYO19 SMCHD1 HEATR1 EFTUD2 ORC1 RIF1 SAFB HNRNPUL2 ANLN LTN1 UBA6 ACIN1 PRPF19 PUM3 HERC2 MTREX PCCB DYNC1H1

7.90e-05144514324int:EED
InteractionXRCC5 interactions

MYCN NANOG MPDZ EFTUD2 OVOL2 ORC1 SAFB THRA THRB BRCA2 ANLN FMNL1 DYNC1H1

7.93e-0551514313int:XRCC5
InteractionTRIM28 interactions

MYCN SETD1A AKAP8 TCP1 WDR33 DDX52 NANOG HEATR1 ANKHD1 ZNF518A EFTUD2 PPP4R3B NBAS UBE2O SAFB SUGP2 BRCA2 ANLN PSMG1 LTN1 ANKRD17 PUM3 MTREX DYNC1H1

1.07e-04147414324int:TRIM28
InteractionMTREX interactions

MYCN NANOG EFTUD2 UBE2O ANLN PRPF19 PUM3 MTREX MTDH

1.08e-042621439int:MTREX
InteractionCHD4 interactions

MYCN SETD1A AKAP8 DDX52 NANOG ANKHD1 EFTUD2 UBE2O SAFB SUGP2 BRCA2 HNRNPUL2 ZNF592 ACIN1 PRPF19 PUM3 MTREX MTDH

1.18e-0493814318int:CHD4
InteractionPRG4 interactions

BRCA2 ANLN PRG4

1.20e-04141433int:PRG4
InteractionCDH5 interactions

ATP13A1 HEATR1 VANGL2 NBAS SBF1 ASPM

1.28e-041091436int:CDH5
InteractionEFL1 interactions

MYCN TCP1 EFTUD2 PRPF19 MTREX

1.31e-04691435int:EFL1
InteractionRNF2 interactions

MYCN ZC3H14 DDX31 AKAP8 OGFR DDX52 NANOG SMCHD1 HEATR1 EFTUD2 SUGP2 HNRNPUL2 ACIN1 PRPF19 PUM3 MTDH DYNC1H1

1.41e-0486614317int:RNF2
InteractionSYF2 interactions

MYCN NANOG EFTUD2 UBE2O PRPF19

1.50e-04711435int:SYF2
InteractionTERF2IP interactions

SETD1A ZC3H14 SETX CENPC WDR33 OGFR SMCHD1 ORC1 RIF1 SUGP2 BRCA2 ZNF592 ANLN

1.58e-0455214313int:TERF2IP
InteractionIFI16 interactions

SEH1L ZC3H14 TCP1 DDX52 SMCHD1 HEATR1 EFTUD2 SAFB ANLN ASPM ACIN1 PRPF19 PUM3 MTREX MTDH

1.72e-0471414315int:IFI16
InteractionMKRN1 interactions

MYCN AKAP8 SMCHD1 UBE2O HNRNPUL2 PRPF19 PUM3

1.79e-041651437int:MKRN1
InteractionNOB1 interactions

MYCN RIOK3 ANKHD1 EFTUD2 UBE2O ANLN

1.80e-041161436int:NOB1
InteractionTUBB4B interactions

MYCN SETX AKAP8 TCP1 NANOG INPPL1 ANKHD1 EFTUD2 UBE2O THRB ANLN HERC2 DYNC1H1

1.82e-0456014313int:TUBB4B
InteractionCCDC140 interactions

DDX31 CENPC ANKHD1 UBE2O ANKRD17 PUM3

1.88e-041171436int:CCDC140
InteractionDOT1L interactions

MYCN SEH1L ZC3H14 DDX31 AKAP8 DDX52 NANOG HEATR1 EFTUD2 ORC1 RIF1 SAFB ZNF592 ACIN1 PUM3 MTREX

2.00e-0480714316int:DOT1L
InteractionSIPA1 interactions

MYO19 ANLN HERC2 FMNL1

2.01e-04411434int:SIPA1
InteractionCBX3 interactions

MYCN SETD1A CENPC NANOG SMCHD1 COBLL1 HEATR1 GTF2IRD1 ZNF568 ZNF518A EFTUD2 RIF1 UBE2O ANLN

2.08e-0464614314int:CBX3
InteractionHECTD1 interactions

ZC3H14 DDX31 AKAP8 DDX52 SMCHD1 TRAIP HEATR1 EFTUD2 RIF1 SUGP2 HNRNPUL2 ASPM ACIN1 PRPF19 PUM3 HERC2 MTREX MTDH

2.13e-0498414318int:HECTD1
InteractionNLE1 interactions

DDX31 CENPC HEATR1 ZNF532 ANLN PUM3 MTREX PCCB

2.28e-042281438int:NLE1
InteractionRNPS1 interactions

MYCN ZC3H14 CENPC WDR33 EFTUD2 UBE2O ANLN ACIN1 PRPF19 HERC2 MTREX

2.30e-0442514311int:RNPS1
InteractionCT45A5 interactions

SETD1A ANKHD1 PPP4R3B UBE2O ANKRD17

2.34e-04781435int:CT45A5
InteractionUTP14A interactions

MYCN WDR33 EFTUD2 SAFB ANLN ACIN1 PRPF19 PUM3

2.42e-042301438int:UTP14A
InteractionMECOM interactions

AKAP8 TCP1 SMCHD1 DZIP1 NLRP14 HNRNPUL2 PRPF19 PUM3 MTREX DYNC1H1

2.44e-0435814310int:MECOM
InteractionPLEC interactions

MYO19 SPEF2 ASH1L TFDP3 EFTUD2 THRB BRCA2 ANLN HERC2 MTDH FMNL1

2.55e-0443014311int:PLEC
InteractionSMC5 interactions

ZC3H14 SETX CENPC ACAT1 WDR33 SMCHD1 HEATR1 EFTUD2 RIF1 SAFB SUGP2 BRCA2 ANLN ACIN1 PRPF19 PUM3 RPRD2 MTDH

2.60e-04100014318int:SMC5
InteractionTOP3B interactions

MYCN SETD1A GTPBP6 ATP13A1 INPPL1 HECTD4 PEX6 APOB GTF2IRD1 ANKHD1 C2CD2 TBC1D24 ORC1 SAFB SBF1 SUGP2 ZNF592 SBF2 ACIN1 ANKRD17 HERC2 DYNC1H1 IGSF3

2.72e-04147014323int:TOP3B
InteractionYWHAH interactions

ZC3H14 SORBS2 SETX SPAST AKAP8 KIAA0232 INPPL1 COBLL1 HECTD4 MPDZ DZIP1 EFTUD2 THRA SBF1 ANLN ANKRD17 REEP4 MTREX FAM110B

2.98e-04110214319int:YWHAH
InteractionACIN1 interactions

MYCN UBE2O SAFB SBF1 BRCA2 HNRNPUL2 ANLN ACIN1 MTDH

3.05e-043011439int:ACIN1
InteractionMAP7 interactions

MYCN EFTUD2 SERPINB8 THRB SBF1 SUGP2 ANLN HERC2

3.13e-042391438int:MAP7
InteractionFUS interactions

MYCN AKAP8 ACAT1 TCP1 WDR33 EFTUD2 SAFB THRA HNRNPUL2 ANLN ACIN1 PRPF19 RPRD2 MTREX DYNC1H1

3.22e-0475714315int:FUS
InteractionSNRPB interactions

MYCN ZC3H14 AKAP8 NANOG EFTUD2 SAFB HNRNPUL2 ANLN ACIN1 PRPF19 RPRD2 DYNC1H1

3.24e-0451714312int:SNRPB
InteractionTHRAP3 interactions

MYCN ZC3H14 SPAST AKAP8 EFTUD2 OVOL2 UBE2O THRA BRCA2 ANLN ACIN1

3.28e-0444314311int:THRAP3
InteractionCUL7 interactions

MYCN ZC3H14 ACAT1 TCP1 SMCHD1 APOB HEATR1 EFTUD2 RIF1 SAFB HNRNPUL2 ACIN1 PRPF19 MTREX MTDH DYNC1H1

3.35e-0484514316int:CUL7
InteractionLUC7L interactions

MYCN ZC3H14 NANOG EFTUD2 VANGL2 UBE2O ACIN1 HERC2

3.40e-042421438int:LUC7L
InteractionFXR1 interactions

MYCN AKAP8 NANOG ANKHD1 EFTUD2 SBF1 HNRNPUL2 ANLN UBA6 ANKRD17 GRIP2 HERC2 PCCB MTDH

3.45e-0467914314int:FXR1
InteractionTHOC5 interactions

MYCN ZC3H14 NANOG ANLN HERC2 FMNL1

3.47e-041311436int:THOC5
InteractionPRPF19 interactions

MYCN SETD1A EFTUD2 PPP4R3B UBE2O ANLN LTN1 PKHD1 PRPF19 MTREX DYNC1H1

3.75e-0445014311int:PRPF19
InteractionTRIM52 interactions

SETX SBF1 BRCA2 ASPM CEP295 PRR14L

3.76e-041331436int:TRIM52
InteractionCDC5L interactions

MYCN SEH1L SETX AKAP8 CENPC TCP1 WDR33 SMCHD1 EFTUD2 ORC1 RIF1 HNRNPUL2 ANLN PRPF19 MTREX DYNC1H1

3.81e-0485514316int:CDC5L
InteractionTHOC6 interactions

MYCN EFTUD2 RIF1 ANLN HERC2

3.88e-04871435int:THOC6
InteractionELAVL2 interactions

MYCN ZC3H14 UBE2O SAFB SUGP2 HNRNPUL2 ACIN1

3.95e-041881437int:ELAVL2
InteractionDIMT1 interactions

MYCN DDX52 EFTUD2 ORC1 UBE2O ANLN LTN1

4.08e-041891437int:DIMT1
InteractionPRPS2 interactions

SETD1A SMCHD1 PEX6 ZNF518A EFTUD2 SBF1 ZNF592 ANLN

4.57e-042531438int:PRPS2
InteractionALB interactions

MYCN GARIN5B SETX DDX31 SPAST KIAA0232 APOB UBE2O ANLN DYNC1H1

4.88e-0439114310int:ALB
InteractionCLK2 interactions

ZC3H14 WDR33 BRCA2 HNRNPUL2 ACIN1 HERC2 MTREX

4.92e-041951437int:CLK2
InteractionCATSPERB interactions

THRB ANLN

4.93e-0451432int:CATSPERB
InteractionZC3H18 interactions

MYCN ZC3H14 WDR33 DDX52 HEATR1 ADARB2 EFTUD2 SAFB SUGP2 HNRNPUL2 ANLN ACIN1 PRPF19 PUM3 MTREX MTDH

5.03e-0487714316int:ZC3H18
Cytoband2p24-p23

MATN3 APOB

1.02e-05214722p24-p23
CytobandEnsembl 112 genes in cytogenetic band chr2p24

MYCN MATN3 APOB NBAS

1.39e-04811474chr2p24
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

NPR3 SBF1 SBF2

2.97e-0425953504
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

SETX CENPC DDX52 MYO19 ZNF518A RIF1 SAFB BRCA2 PLXNC1 ANLN CCNE2 ASPM UBA6 ACIN1

1.50e-0553214314Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000

DMXL2 SETX TCP1 SWT1 HEATR1 ATP10A ZNF518A ORC1 RIF1 BRCA2 ANLN CCNE2 PSMG1 UBA6 CEP295 AMMECR1 RNF182

3.85e-0582014317gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000

DMXL2 SETX TCP1 SWT1 NANOG HEATR1 ATP10A ZNF518A EFTUD2 ORC1 RIF1 BRCA2 ANLN PSMG1 PUM3 AMMECR1 RNF182

3.96e-0582214317gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_k-means-cluster#3_top-relative-expression-ranked_1000

CYP1B1 SETD1A SORBS2 COBLL1 ASH1L LYSMD3 TMEM132C ASPM CEP295

4.94e-052491439gudmap_developingGonad_P2_epididymis_1000_k3
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_500

TCP1 NANOG HEATR1 ATP10A ZNF518A ORC1 RIF1 BRCA2 ANLN PUM3 RNF182

6.44e-0538714311gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_500
CoexpressionAtlasalpha beta T cells, T.8Mem.Sp, 4- 8+ 25- 44hi 122hi, Spleen, avg-3

DZIP1 NSG2 CRTAM GRAMD2B CD96

7.15e-05641435GSM538398_100
CoexpressionAtlasalpha beta T cells, T.8.Sp.B16, 4- 8+ TCR+ 45+, B16 Melanoma Spleen, avg-3

DZIP1 NSG2 CRTAM GRAMD2B CD96

8.30e-05661435GSM605770_100
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_k-means-cluster#1_top-relative-expression-ranked_1000

SETX TCP1 HEATR1 ZNF518A EFTUD2 ORC1 RIF1 ANLN PSMG1 MTREX

8.90e-0533314310gudmap_dev gonad_e13.5_M_GermCell_Oct_k1_1000
CoexpressionAtlasdev gonad_e12.5_M_GermCellTestis_Oct_top-relative-expression-ranked_1000

DMXL2 SETX TCP1 SWT1 NANOG HEATR1 ATP10A ZNF518A EFTUD2 ORC1 RIF1 BRCA2 ANLN PSMG1 PUM3 RNF182

9.32e-0579514316gudmap_dev gonad_e12.5_M_GermCellTestis_Oct_1000
CoexpressionAtlasalpha beta T cells, T.8Nve.PP, TCRb+ CD8+ CD44low CD62L high, Peyer's Patch, avg-1

DZIP1 NSG2 CRTAM GRAMD2B CD96

1.03e-04691435GSM538413_100
CoexpressionAtlasalpha beta T cells, T.8Nve.PP, TCR+ CD8+ CD44low CD62Lhigh, Peyer's Patch, avg-1

DZIP1 NSG2 CRTAM GRAMD2B CD96

1.03e-04691435GSM538412_100
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_500

CYP1B1 SETD1A ASH1L LYSMD3 RIF1 PLXNC1 CCNE2 ASPM ACIN1 CEP295 RNF182

1.05e-0440914311gudmap_developingGonad_e12.5_ovary_500
CoexpressionAtlasalpha beta T cells, T.8Eff.Sp.OT1.d5.VSVOva, CD8+ CD45.1+, Spleen, avg-3

COBLL1 ATP10A ORC1 BRCA2 ANLN CCNE2 GZMK CRTAM GRAMD2B ASPM CD96

1.08e-0441014311GSM538387_500
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_top-relative-expression-ranked_1000

MYCN CYP1B1 SETD1A WDR33 ASH1L ANKHD1 LYSMD3 RIF1 PLXNC1 CCNE2 ASPM ACIN1 ANKRD17 CEP295 RNF182 IGSF3

1.09e-0480614316gudmap_developingGonad_e12.5_epididymis_1000
CoexpressionAtlasCD positive, T.8Nve.Sp.OT1, CD8+ CD45.1+, Spleen, avg-3

DZIP1 NSG2 CRTAM GRAMD2B CD96

1.10e-04701435GSM605909_100
CoexpressionAtlasdev gonad_e13.5_M_GermCell_Oct_top-relative-expression-ranked_1000

DMXL2 SETX TCP1 SWT1 NANOG HEATR1 ATP10A ZNF518A EFTUD2 ORC1 RIF1 BRCA2 ANLN PSMG1 PUM3 MTREX

1.16e-0481014316gudmap_dev gonad_e13.5_M_GermCell_Oct_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

SORBS2 TMA16 HEATR1 GTF2IRD1 ANKHD1 ZNF518A ORC1 RIF1 SAFB NSG2 BRCA2 HNRNPUL2 PLXNC1 PTPRZ1 CCNE2 ASPM PUM3 CEP295

1.20e-0498914318Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasDevelopingGonad_e18.5_epididymis_emap-13166_k-means-cluster#3_top-relative-expression-ranked_1000

CYP1B1 SETD1A SORBS2 COBLL1 ASH1L LYSMD3 TMEM132C ASPM CEP295

1.24e-042811439gudmap_developingGonad_e18.5_epididymis_1000_k3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

DMXL2 SWT1 ASH1L GTF2IRD1 ANKHD1 FMNL2 ZNF518A RIF1 SAFB BRCA2 PLXNC1 PTPRZ1 CCNE2 ASPM CEP295 PRR14L

1.55e-0483114316Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasdev gonad_e11.5_M_PrimGermCell_Oct_top-relative-expression-ranked_1000

TMA16 SETX TCP1 NANOG HEATR1 ATP10A ZNF518A EFTUD2 ORC1 RIF1 BRCA2 ANLN PSMG1 PUM3 RNF182

2.58e-0478114315gudmap_dev gonad_e11.5_M_PrimGermCell_Oct_1000
CoexpressionAtlasdev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500

DMXL2 TCP1 SWT1 ZNF518A ORC1 RIF1 BRCA2 ANLN PSMG1 UBA6

2.88e-0438514310gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

TMA16 SETX CENPC SWT1 SMCHD1 HEATR1 FMNL2 ORC1 PPP4R3B RIF1 BRCA2 ANLN PTPRZ1 CCNE2 ASPM UBA6 CEP295 MTREX HSD17B2 MTDH

2.96e-04125714320facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasDevelopingGonad_P2_epididymis_emap-30199_top-relative-expression-ranked_1000

CYP1B1 SETD1A SORBS2 WDR33 COBLL1 ASH1L LYSMD3 MFAP3L TMEM132C RIF1 CCNE2 ASPM PKHD1 ACIN1 CEP295

3.20e-0479714315gudmap_developingGonad_P2_epididymis_1000
CoexpressionAtlasfacebase_RNAseq_e8.5_FloorPlate_2500_K3

MYCN SETD1A TMA16 DDX31 SWT1 NANOG COBLL1 HEATR1 BOLA3 ZNF518A ORC1 RIF1 UBE2O BRCA2 PTPRZ1 CCNE2 UBA6 PUM3 AMMECR1 MTREX CADPS2

3.44e-04137114321facebase_RNAseq_e8.5_FloorPlate_2500_K3
CoexpressionAtlasDevelopingGonad_e12.5_ovary_emap-28876_top-relative-expression-ranked_1000

MYCN CYP1B1 SETD1A DMXL2 SMCHD1 ASH1L LYSMD3 RIF1 PLXNC1 CCNE2 ASPM ACIN1 ANKRD17 CEP295 RNF182

3.51e-0480414315gudmap_developingGonad_e12.5_ovary_1000
CoexpressionAtlasalpha beta T cells, T.DPbl.Th, 4+ 8+ TCR-/lo FSChi, Thymus, avg-3

CENPC DZIP1 GTF2IRD1 ATP10A NSG2 BRCA2 ANLN CCNE2 ASPM CD96

3.74e-0439814310GSM399397_500
CoexpressionAtlasDevelopingGonad_e12.5_epididymis_emap-29139_k-means-cluster#3_top-relative-expression-ranked_1000

CYP1B1 SETD1A WDR33 ASH1L LYSMD3 ASPM CEP295 IGSF3

3.79e-042591438gudmap_developingGonad_e12.5_epididymis_k3_1000
CoexpressionAtlasdev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500

DMXL2 NANOG HEATR1 ATP10A ORC1 RIF1 BRCA2 ANLN PSMG1 RNF182

4.37e-0440614310gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

DMXL2 ADCY3 ORC1 NBAS SUGP2 BRCA2 ANLN CCNE2 ASPM

2.29e-082001479d933978b55fefe52cad599b36f6b47a0c7f71f96
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Stem_cells-Neuroepithelial_cell|GW13 / Sample Type, Dataset, Time_group, and Cell type.

DMXL2 ADCY3 ORC1 NBAS SUGP2 BRCA2 ANLN CCNE2 ASPM

2.29e-0820014793d932765c31aef1f80a118d51e8e66c50a758dbb
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MAP4K3 GTF2IRD1 MFAP3L TMEM132C THRA RGS6 SBF1

7.49e-071521477ca23261d8ef263cc697b8d7e7cb2afec8bc564f2
ToppCell368C-Lymphocytic-CD4_T-cell-CD4+_Naive_T_cell_/_CD4+_Trm_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

MAP4K3 CCDC168 GTF2IRD1 MFAP3L TMEM132C RGS6 SBF1

1.06e-06160147719105debef96ea0c267d6a1d332303ec668ae47e
ToppCellhuman_hepatoblastoma-Tumor_cells-T2|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

SORBS2 COBLL1 PLPPR1 THRB PLXNC1 SBF2 PKHD1

2.99e-061871477f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAP4K3 COBLL1 GTF2IRD1 RGS6 PKHD1 CADPS2 FAM110B

3.20e-06189147790aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP4K3 COBLL1 GTF2IRD1 RGS6 PKHD1 CADPS2 FAM110B

3.32e-0619014774836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCellControl-Neu_4|Control / 5 Neutrophil clusters in COVID-19 patients

CENPC HEATR1 LYSMD3 MFAP3L ANLN ASPM MTDH

4.07e-061961477b8b7b54ca17a08fa775507bb22b1c7248ada8f40
ToppCellFibroblasts-DKK3+_Fibroblasts|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

PRUNE2 COBLL1 CD109 FMNL2 ATP10A PTPRZ1 IGSF3

4.07e-06196147724d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-CARM1P1--L3-4|Neuronal / cells hierarchy compared to all cells using T-Statistic

COBLL1 DCBLD1 GPRC6A CCDC168 BRCA2 PTPRZ1 GRAMD2B

4.65e-06200147747791c93d03ee17c1ce17e27f075be4fc6f2590e
ToppCellControl-Control-Myeloid-immature_Neutrophil|Control / Disease, condition lineage and cell class

SETD1A DMXL2 HEATR1 LYSMD3 MFAP3L ANLN ASPM

4.65e-062001477118321ac443feb42aee171baccfc4610f00a8822
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-CARM1P1|Neuronal / cells hierarchy compared to all cells using T-Statistic

COBLL1 DCBLD1 GPRC6A CCDC168 BRCA2 PTPRZ1 GRAMD2B

4.65e-062001477f75d95376a340d467c4392b872b2a2dbdd184556
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MYO19 TRAIP ADCY3 ORC1 ANLN CCNE2 ASPM

4.65e-0620014772afbb5b5742b956993796621fea7e0c9888754a1
ToppCellNeuronal-Excitatory-eC(RORB)-eC_1-CARM1P1-|Neuronal / cells hierarchy compared to all cells using T-Statistic

COBLL1 DCBLD1 GPRC6A CCDC168 BRCA2 PTPRZ1 GRAMD2B

4.65e-062001477fae26560ba3b0b638b6bcf92f05330824b31d21b
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MYO19 TRAIP ADCY3 ORC1 ANLN CCNE2 ASPM

4.65e-0620014774462ebd5d4632788f10a93fadd2babae701c754f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-cortical_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

MYCN NPR3 PLPPR1 FMNL2 THRA NSG2 RNF182

4.65e-0620014770cb0755a101ec655359d051d6a8807408d727c55
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Crispld2_Htr2c|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CYP1B1 PLPPR1 ADARB2 PTPRZ1 SORCS2 IGSF3

9.14e-06146147647368f981180ca6a8c81a50f7f9430f12456f609
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_104|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

CACNB3 APOB BOLA3 ANLN CCNE2 HSD17B2

1.11e-051511476ea62e92ccb984f44559b434f35c1c4450767c8f1
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

CYP1B1 NPR3 MATN3 ATP10A PLXNC1 SORCS2

1.24e-051541476511923b27469ea20f8bd82a9ec27119a6e884644
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MYO19 ADCY3 ORC1 BRCA2 ANLN CCNE2

2.10e-051691476e7514956b2e4298222ec443f98b2f5289451786e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRCA2 PLXNC1 ANLN CRTAM ASPM FMNL1

2.10e-05169147654b13ab02b4c187f4754045ecfcf409749e7ccc0
ToppCell3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Differentiating_glia|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYCN SORBS2 PLPPR1 ADARB2 PTPRZ1 DAGLA

2.32e-051721476bc3ed05fdd94d5e1f19285aea867b1453292baec
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAIP CD109 C2CD2 RIF1 ANLN CCNE2

2.32e-0517214762b6cd84c946b1e800caba452ae70145ea285fec1
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

MATN3 ZNF568 ANLN ASPM PRG4 IGSF3

2.47e-051741476fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

CENPC COBLL1 RIOK3 SERPINB8 REEP4 IGSF3

2.55e-0517514760cc215109d9915af47e4d0a120ce2e46910715fa
ToppCellsevere_influenza-Plasmablast|World / disease group, cell group and cell class (v2)

SORBS2 CCDC168 ANLN CCNE2 ASPM IGHV4-4

2.55e-051751476e6d6c44510d5dc4eb0bae820125e42366f7a4e74
ToppCellPND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 DMXL2 TRAIP ATP10A EFTUD2 CCNE2

2.64e-051761476450c25ec5eeb65425f904e0a25aaafdf5682ef9c
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPR3 COBLL1 PLPPR1 ADARB2 PTPRZ1 GRIP2

2.72e-051771476fdab7b7ddfb06f913b8224c0c80574dc3cf4cbd4
ToppCellPND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRUNE2 DMXL2 ATP10A TBC1D24 CCNE2 PRG4

2.72e-0517714761d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCelldroplet-Marrow-BM-30m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ORC1 NSG2 CCNE2 CRTAM GRAMD2B CD96

2.72e-051771476650095a17e1a39caea74a6e89646565b9332af5d
ToppCelldroplet-Marrow-BM-30m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ORC1 NSG2 CCNE2 CRTAM GRAMD2B CD96

2.72e-051771476d1af0cb4b1fb03f04cff5add85e29be8fb8f4dcb
ToppCellASK440-Epithelial-Transformed_epithelium|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

MATN3 GTF2IRD1 ADCY3 ASPM PRG4 IGSF3

2.81e-05178147686f1741636ed3e85bb4a65f84949b718fc38c290
ToppCellfacs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRAIP ADCY3 NSG2 CCNE2 TSTD2 CD96

2.99e-05180147687347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRUNE2 THRB PTPRZ1 SORCS2 CADPS2 RNF182

2.99e-051801476b7513b9816a9cb9f3caaddb2a9fed0be1c7f9805
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRUNE2 THRB PTPRZ1 SORCS2 CADPS2 RNF182

2.99e-051801476f96c5be4705e3d338c0393d2885ac8d5beccd6fd
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DCBLD1 GTF2IRD1 FMNL2 TBC1D24 RGS6 CCNE2

3.28e-0518314763ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRUNE2 ATP10A ASPM SORCS2 CADPS2 RNF182

3.28e-0518314763ebe334ad570e3525341badb558f369c61daf3d3
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SETD1A DMXL2 HEATR1 MFAP3L ANLN ASPM

3.38e-051841476a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SETD1A DMXL2 HEATR1 MFAP3L ANLN ASPM

3.38e-051841476081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

SETD1A DMXL2 HEATR1 MFAP3L ANLN ASPM

3.38e-05184147645f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

SETD1A DMXL2 HEATR1 MFAP3L ANLN ASPM

3.38e-05184147684c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SETD1A DMXL2 HEATR1 MFAP3L ANLN ASPM

3.38e-051841476d31d4116d1d196633784863781fa45673607a421
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DMXL2 TRAIP ATP10A ANLN CCNE2 ASPM

3.38e-05184147616aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP4K3 COBLL1 GTF2IRD1 RGS6 CADPS2 FAM110B

3.59e-051861476d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAP4K3 COBLL1 GTF2IRD1 RGS6 CADPS2 FAM110B

3.59e-05186147608632045d499e61dd96ff29a5a9a208afe58dc58
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

NPR3 SETX SMCHD1 RGS6 LTN1 CEP295

3.59e-05186147603db813598b67b1e08f759758a1c2023396921fa
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 COBLL1 DZIP1 GTF2IRD1 ADARB2 PKHD1

3.70e-051871476c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPR3 PLPPR1 ADARB2 NSG2 PTPRZ1 IGSF3

3.81e-051881476c66fccdfe68760b8c3efca77e3c25966dc9a8a5f
ToppCellMultiple_Sclerosis-Lymphocyte-T_NK-T_NK_proliferative|Multiple_Sclerosis / Disease, Lineage and Cell Type

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

3.81e-0518814766c05797a5d0635d89ffcf4aca52178687129ccb4
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 GTF2IRD1 RGS6 SORCS2 CADPS2 FAM110B

3.81e-0518814764154f4787483c7e076e87a187733a9f666742c3d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAP4K3 COBLL1 GTF2IRD1 PKHD1 CADPS2 FAM110B

3.93e-0518914768ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

COBLL1 THRB SORCS2 PKHD1 ANKRD17 CADPS2

3.93e-051891476830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASH1L APOB MFAP3L ZNF518A PPP4R3B MTDH

4.16e-05191147660c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASH1L APOB MFAP3L ZNF518A PPP4R3B MTDH

4.16e-05191147609db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ASH1L APOB MFAP3L ZNF518A PPP4R3B MTDH

4.16e-051911476973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

COBLL1 PLPPR1 OVOL2 PTPRZ1 ASPM PKHD1

4.29e-05192147625378b5e4b0cea8415ff125783511fc25a56fc00
ToppCellCOVID-19-kidney-CNT|kidney / Disease (COVID-19 only), tissue and cell type

COBLL1 GTF2IRD1 RGS6 PKHD1 CADPS2 FAM110B

4.29e-051921476d32ae226d95b4b6adb99d14b602be09b661d4cd9
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MYCN SORBS2 COBLL1 PLPPR1 PTPRZ1 PKHD1

4.29e-051921476b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP4K3 COBLL1 GTF2IRD1 SORCS2 CADPS2 FAM110B

4.29e-0519214762510f22197502f60fd266b7f42eff040f25b8ae7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP4K3 COBLL1 GTF2IRD1 SORCS2 CADPS2 FAM110B

4.29e-051921476e8e316f396834bcd34843e56e1d86f310fd6aada
ToppCellFetal_brain-fetalBrain_Zhong_nature|Fetal_brain / Sample Type, Dataset, Time_group, and Cell type.

PLPPR1 ZNF518A PPP4R3B NSG2 PUM3 CEP295

4.41e-0519314761553c856f3b71c1b0a78ec8d59c7948144d9c5bb
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP4K3 COBLL1 GTF2IRD1 SORCS2 PKHD1 CADPS2

4.54e-05194147646070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MAP4K3 COBLL1 GTF2IRD1 SORCS2 PKHD1 CADPS2

4.54e-051941476abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCellHealthy/Control-T/NK_proliferative|Healthy/Control / Disease group and Cell class

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

4.67e-051951476957458fdc39723f4a31bd7fd3ce32891aa3fd462
ToppCellsevere_COVID-19-T/NK_proliferative|World / disease group, cell group and cell class (v2)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

4.95e-051971476189d97a6c2ff8803db8cc05e205c9d88dac3911f
ToppCellHealthy/Control-T/NK_proliferative|World / Disease group and Cell class

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

4.95e-0519714764a4d3083938783d6f5b87da02f10e501917da0b4
ToppCellproximal-Hematologic-Proliferating_Macrophage|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

4.95e-0519714760b1fa881abbfcc54b322fc27124db3f8947af016
ToppCellproximal-3-Hematologic-Proliferating_Macrophage|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

4.95e-0519714760dd9058aa19d1268ebba9a65555870224b5a5978
ToppCellproximal-Hematologic-Proliferating_Macrophage-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

4.95e-0519714769243617b307acf3df40d93c41cd8d4788699a7ea
ToppCellHealthy_donor-T/NK_proliferative|Healthy_donor / disease group, cell group and cell class (v2)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

4.95e-051971476b6bbf87e5823fa66b4cad6a7be4f777356887b59
ToppCellCOVID-19_Moderate-T/NK_proliferative|COVID-19_Moderate / disease group, cell group and cell class

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.09e-051981476166c000fb0e19602ffdd8bf2b2f19be2c6df96a6
ToppCellsevere_COVID-19-T/NK_proliferative|severe_COVID-19 / disease group, cell group and cell class (v2)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.09e-051981476ed86b0247006befe55400c287d334d2202b470bd
ToppCellCOVID-19_Moderate-T/NK_proliferative|World / disease group, cell group and cell class

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.09e-051981476bf0131fbca6032e1aab4aa807f8c1d3be689cb7f
ToppCellmedial-2-Hematologic-Proliferating_Macrophage|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.09e-05198147664a2bcf5a9ba66a4fe08fbde33f1886c136cde8f
ToppCellmedial-Hematologic-Proliferating_Macrophage-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.09e-051981476fcc14ac3eb5088b9d6cd6af5a34dee5b81c0ece8
ToppCelldistal-1-Hematologic-Proliferating_Macrophage|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.09e-051981476df3f5559ecd1f3cd1fd60e39dbad8741309e83a3
ToppCelldistal-Hematologic-Proliferating_Macrophage-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.09e-0519814762b0716e900bce54ad1825d6dcdaf4ebf31f355c4
ToppCellCOVID-19_Severe-T/NK_proliferative|World / disease group, cell group and cell class

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.09e-05198147648045689d0969ff0a14eee7086b8e19b0d6b6065
ToppCellmedial-Hematologic-Proliferating_Macrophage|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.09e-051981476da6963184c32761c896a9b91a5321ad84b583736
ToppCell10x3'2.3-week_14-16-Hematopoietic-erythroid-early_erythroid|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ACAT1 BOLA3 PSMG1 AMMECR1 PCCB RNF182

5.09e-05198147636c848b747903ff875ebb241eefbcd889f39be29
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-05199147611c3d9fe811a4619347f47d2b0e94066e3085625
ToppCellmild_COVID-19-T/NK_proliferative|World / disease group, cell group and cell class (v2)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-051991476d44cc74d7171d96add61dae821daf774b17d4c69
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-05199147636c80907b2ec1cbcd1b4e841e6c02a4792591d74
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-051991476bf4c31902ae8358215245a2e11b5a2fe4ca1bc8c
ToppCellCOVID-19_Mild-Lymphoid_T/NK-T/NK_proliferative|COVID-19_Mild / Disease group, lineage and cell class

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-051991476ddea0e5c1cb6a096ab8e09a8c3c37c1bff381d9c
ToppCellBiopsy_Control_(H.)-Epithelial-Proliferating_Epithelial_cells|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

MYO19 ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-0519914764fcf5bec207e4384fd73c5e8801a7e414e3ee7b0
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

ANKHD1 ADCY3 NBAS ANLN CCNE2 ASPM

5.23e-051991476fd1d1b95e01719e3d0a17d9d1f29717a47209d32
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-051991476101f78fe6dd1bf9e2e4dd5ad8a970312b3540927
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-T/NK_proliferative|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-0519914767beb0e07a27fea94674f24eb61c381b0de38ed3e
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-051991476e0fcec796afe75e42467ca86355b9fc5aa9ae0a1
ToppCellCOVID-19_Mild-T/NK_proliferative|COVID-19_Mild / Disease condition and Cell class

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-0519914769f9a88d2b099646c1e1a7ee3f8d39cb1a2498ad7
ToppCellHealthy_donor-T/NK_proliferative|World / disease group, cell group and cell class (v2)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-0519914761311dfd74b991f48b047a439f04f9bf7dfaa0e7a
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

MAP4K3 FMNL2 NBAS THRB SBF2 CADPS2

5.23e-05199147694b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellDividing_Macrophages|World / lung cells shred on cell class, cell subclass, sample id

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-0519914765c755b6876e164dc847ef7c723f850f227cf3a87
ToppCellmild_COVID-19-T/NK_proliferative|mild_COVID-19 / disease group, cell group and cell class (v2)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-051991476df2fcaf01b1b48632f84e7355ef21d20853f0664
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW13-Stem_cells-Stem_cells|GW13 / Sample Type, Dataset, Time_group, and Cell type.

ANKHD1 ADCY3 NBAS ANLN CCNE2 ASPM

5.23e-05199147691882af9dc7265c9b419f4415cbcf656087a2ab3
ToppCellMild-T/NK_proliferative|Mild / Disease group and Cell class

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.23e-05199147664a5c91243ee999ea21ffddd450d3e5fdbf6470b
ToppCelldistal-Hematologic-Proliferating_Macrophage|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.38e-0520014763835a8a9739b8cd5bf19c40765ef76907ac1ad38
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-T/NK_proliferative|COVID-19_Mild / Disease, condition lineage and cell class

TRAIP ORC1 BRCA2 ANLN CCNE2 ASPM

5.38e-0520014766126a3bbafe2110fba0c1c4493035df4e8193d22
ToppCellNS-moderate-d_07-13-Lymphoid-NKT-proliferating|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ORC1 BRCA2 ANLN CCNE2 GZMK ASPM

5.38e-05200147687e293c0882e2754756a2210a6c04723dc89f81b
DrugRapamycin; Down 200; 0.1uM; MCF7; HT_HG-U133A

DDX31 AKAP8 OGFR DDX52 KIAA0232 INPPL1 MPDZ MFAP3L SAFB ZNF592 ACIN1

4.76e-08195144116927_DN
DrugHarmine hydrochloride [343-27-1]; Down 200; 16uM; MCF7; HT_HG-U133A

CYP1B1 CACNB3 SPAST MPDZ GTF2IRD1 OVOL2 MLH3 CCNE2 PUM3 MTDH

2.95e-07185144107209_DN
Drug0175029-0000 [211245-78-2]; Down 200; 1uM; MCF7; HT_HG-U133A

SEH1L SPAST OGFR DDX52 MPDZ C2CD2 MFAP3L MLH3 BRCA2 CCNE2

3.59e-07189144104716_DN
DrugTrichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA

CYP1B1 AKAP8 INPPL1 COBLL1 GTF2IRD1 RIF1 SAFB RPRD2

1.82e-0517814481112_DN
DrugAG-1478; Down 200; 31.6uM; MCF7; HT_HG-U133A_EA

CYP1B1 AKAP8 MPDZ SAFB CCNE2 ASPM ACIN1 IGSF3

2.59e-0518714481141_DN
DrugNRB02976

ACAT1 NANOG APOB ACIN1 DYNC1H1

3.30e-05581445CID005354459
DrugCyproterone acetate [427-51-0]; Up 200; 9.6uM; HL60; HT_HG-U133A

PRUNE2 CACNB3 OGFR COBLL1 PEX6 ATP10A NME8 MLH3

3.49e-0519514486124_UP
DrugDeptropine citrate [2169-75-7]; Up 200; 7.6uM; HL60; HT_HG-U133A

TFDP3 PLPPR1 MFAP3L RIF1 UBE2O THRA RPRD2 FMNL1

3.62e-0519614483144_UP
DrugTolbutamide [64-77-7]; Down 200; 14.8uM; PC3; HT_HG-U133A

SETD1A WDR33 DDX52 TRAIP ASH1L DZIP1 MFAP3L PLXNC1

3.62e-0519614484540_DN
DrugFluvastatin sodium salt [93957-55-2]; Down 200; 9.2uM; MCF7; HT_HG-U133A

AKAP8 KIAA0232 MYO19 SMCHD1 COBLL1 MPDZ UBE2O ZNF592

3.62e-0519614485290_DN
DrugCiprofibrate [52214-84-3]; Down 200; 13.8uM; MCF7; HT_HG-U133A

DDX52 INPPL1 COBLL1 TRAIP ADCY3 SAFB SUGP2 HNRNPUL2

3.76e-0519714486218_DN
DrugPaclitaxel [33069-62-4]; Down 200; 4.6uM; MCF7; HT_HG-U133A

CACNB3 KIAA0232 INPPL1 ADCY3 PPP4R3B NBAS CCNE2 RPRD2

3.76e-0519714485320_DN
DrugLevothyroxine

THRA THRB

3.97e-0521442DB00451
DrugLiothyronine

THRA THRB

3.97e-0521442DB00279
DrugLiotrix

THRA THRB

3.97e-0521442DB01583
Drug3,5-Dichloro-4-[(4-Hydroxy-3-Isopropylphenoxy)Phenylacetic Acid

THRA THRB

3.97e-0521442DB03176
DrugKB 130015

THRA THRB

3.97e-0521442ctd:C446946
DrugRafoxanide

THRA THRB

3.97e-0521442ctd:D011888
DrugTriamcinolone [124-94-7]; Down 200; 10.2uM; MCF7; HT_HG-U133A

CYP1B1 CACNB3 OGFR MYO19 COBLL1 TRAIP MPDZ SBF1

4.04e-0519914487192_DN
Diseasethyroid hormone resistance syndrome (implicated_via_orthology)

THRA THRB

6.68e-0531402DOID:11633 (implicated_via_orthology)
DiseaseGeneralized Thyroid Hormone Resistance

THRA THRB

1.33e-0441402C4722330
DiseaseDwarfism

TRAIP ORC1 AMMECR1

2.23e-04251403C0013336
DiseaseSevere Congenital Microcephaly

TRAIP ORC1 DYNC1H1

4.26e-04311403C3853041
Diseasefree androgen index

CYP3A7 SMCHD1 COBLL1 TRAIP GTF2IRD1 SERPINB8 THRB PCCB

4.32e-043741408EFO_0007005
Diseaseabnormal vaginal discharge smell

SORBS2 KCNJ6

4.62e-0471402EFO_0009408
DiseaseMicrolissencephaly

TRAIP ORC1 DYNC1H1

5.14e-04331403C1956147
Diseasesmall cell lung carcinoma

TMA16 RGS6 BRCA2 CRTAM

5.81e-04801404EFO_0000702
Diseasemicrocephaly (is_implicated_in)

EFTUD2 ASPM

6.14e-0481402DOID:10907 (is_implicated_in)
Diseasegait measurement

SWT1 TRAIP ZNF568 PCCB IGSF3

7.63e-041501405EFO_0007680
Diseasebreast cancer

ADARB2 KCNJ6

7.87e-0491402MONDO_0007254
DiseaseCharcot-Marie-Tooth disease

SBF1 SBF2 DYNC1H1

1.05e-03421403cv:C0007959
Diseasetriglycerides in large LDL measurement

COBLL1 APOB PCCB

1.12e-03431403EFO_0022319
Diseasevisual epilepsy (is_implicated_in)

TBC1D24 ASPM

1.20e-03111402DOID:11832 (is_implicated_in)
Diseasecolon cancer (implicated_via_orthology)

NANOGP8 NANOG

1.20e-03111402DOID:219 (implicated_via_orthology)
DiseaseSeizures, Focal

ACAT1 MPDZ PLPPR1 DYNC1H1

1.55e-031041404C0751495
DiseaseCharcot-Marie-Tooth disease type 4

SBF1 SBF2

1.68e-03131402cv:C4082197
DiseaseDuchenne muscular dystrophy, disease progression measurement

SPEF2 RGS6 NSG2

1.74e-03501403EFO_0008336, MONDO_0010679
Diseasecholesteryl esters to total lipids in IDL percentage

COBLL1 APOB PCCB

1.74e-03501403EFO_0022247
DiseaseC-reactive protein measurement

CYP3A7 DMXL2 DDX52 COBLL1 TRAIP GPRC6A APOB CCDC168 ADCY3 RGS6 THRB KCNJ6 PCCB DAGLA

1.83e-03120614014EFO_0004458
Diseasetriglycerides to total lipids in large LDL percentage

COBLL1 APOB PCCB

1.84e-03511403EFO_0022331
Diseasecholesterol to total lipids in small HDL percentage

COBLL1 APOB PCCB

1.84e-03511403EFO_0022240
DiseaseMalignant neoplasm of breast

CYP1B1 SPAST AKAP8 TCP1 CD109 NME8 RIF1 NLRP14 BRCA2 ZNF532 HERC2 MTDH RNF182

1.85e-03107414013C0006142
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

APOB ANKRD17

1.96e-03141402EFO_0004611, EFO_0008589
DiseaseColorectal Carcinoma

CYP1B1 CD109 APOB ADARB2 MLH3 PKHD1 ACIN1 MTDH RNF182 FAM110B

1.96e-0370214010C0009402
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

COBLL1 APOB BRCA2 PCCB

1.96e-031111404EFO_0004530, EFO_0008595
Diseasetriglycerides in HDL measurement

COBLL1 APOB PCCB

2.06e-03531403EFO_0022317
Diseasefree cholesterol to total lipids in small LDL percentage

COBLL1 APOB PCCB

2.06e-03531403EFO_0022286
Diseasewaist-hip ratio

PRUNE2 DMXL2 NPR3 SMCHD1 COBLL1 TRAIP HECTD4 RIOK3 ADCY3 ZNF568 VANGL2 KCNJ6 SBF2 PCCB

2.13e-03122614014EFO_0004343
Diseasetriglycerides in LDL measurement

COBLL1 APOB PCCB

2.41e-03561403EFO_0022320
Diseasetriglycerides in very large VLDL measurement

COBLL1 APOB PCCB

2.41e-03561403EFO_0022325
Diseasetriglycerides to total lipids in medium HDL percentage

COBLL1 APOB PCCB

2.41e-03561403EFO_0022333
Diseasetriglycerides in chylomicrons and extremely large VLDL measurement

COBLL1 APOB PCCB

2.41e-03561403EFO_0022316
Diseasecholesteryl esters to total lipids in medium HDL percentage

COBLL1 APOB PCCB

2.41e-03561403EFO_0022251
Diseasetriglycerides in IDL measurement

COBLL1 APOB PCCB

2.67e-03581403EFO_0022149
Diseasemetabolic syndrome

COBLL1 HECTD4 APOB PPP4R3B PCCB

2.71e-032001405EFO_0000195
Diseasetriglycerides in VLDL measurement

COBLL1 APOB PCCB

2.80e-03591403EFO_0022326
Diseasetriglycerides to total lipids in small LDL percentage

COBLL1 APOB PCCB

2.80e-03591403EFO_0022337
Diseasephospholipids in VLDL measurement

COBLL1 APOB PCCB

2.80e-03591403EFO_0022301
Diseaseconcentration of chylomicrons and extremely large VLDL particles measurement

COBLL1 APOB PCCB

2.80e-03591403EFO_0022260
Diseasetriglycerides to total lipids in large HDL percentage

COBLL1 APOB PCCB

2.94e-03601403EFO_0022330
Diseasetotal lipids in VLDL measurement

COBLL1 APOB PCCB

2.94e-03601403EFO_0022314
Diseasecholesterol to total lipids in IDL percentage

COBLL1 APOB PCCB

2.94e-03601403EFO_0022233
Diseasepuberty onset measurement

MCHR2 ADARB2 PSMG1 HERC2

3.02e-031251404EFO_0005677
Diseasetestosterone measurement

CYP3A7 COBLL1 TRAIP MCHR2 GTF2IRD1 C2CD2 SERPINB8 RGS6 THRB SBF2 CRTAM HSD17B2 PCCB FAM110B

3.03e-03127514014EFO_0004908
Diseasetriglycerides in small VLDL measurement

COBLL1 APOB PCCB

3.08e-03611403EFO_0022145
Diseasefree cholesterol in very large VLDL measurement

COBLL1 APOB PCCB

3.08e-03611403EFO_0022274
Diseasefree cholesterol in VLDL measurement

COBLL1 APOB PCCB

3.08e-03611403EFO_0022276
Diseasetriglycerides in small HDL measurement

COBLL1 APOB PCCB

3.22e-03621403EFO_0022158
Diseasephospholipids in large VLDL measurement

COBLL1 APOB PCCB

3.22e-03621403EFO_0022169
Diseasetriglycerides in medium LDL measurement

COBLL1 APOB PCCB

3.22e-03621403EFO_0022322
Diseasetotal lipids in chylomicrons and extremely large VLDL measurement

COBLL1 APOB PCCB

3.22e-03621403EFO_0022306
Diseasetotal lipids in very large VLDL measurement

COBLL1 APOB PCCB

3.22e-03621403EFO_0022313
Diseasephospholipids in very large VLDL measurement

COBLL1 APOB PCCB

3.22e-03621403EFO_0022299
Diseasesphingosine 1-phosphate measurement

UBE2O SORCS2

3.25e-03181402EFO_0800185
DiseaseDisorder of organic acid metabolism

ACAT1 PCCB

3.25e-03181402cv:C1263739
Diseasetriglycerides to total lipids in IDL percentage

COBLL1 APOB PCCB

3.37e-03631403EFO_0022329
Diseasefree cholesterol to total lipids in medium LDL percentage

COBLL1 APOB PCCB

3.37e-03631403EFO_0022283
Diseasephospholipids in chylomicrons and extremely large VLDL measurement

COBLL1 APOB PCCB

3.37e-03631403EFO_0022292
DiseaseChronic myeloproliferative disorder

TRAIP ORC1

3.63e-03191402C1292778
Diseasetriglycerides in small LDL measurement

COBLL1 APOB PCCB

3.68e-03651403EFO_0022323
Diseasecholesterol in large VLDL measurement

COBLL1 APOB PCCB

3.68e-03651403EFO_0021902
Diseasesusceptibility to vaginal yeast infection measurement

NANOGP8 PKHD1 AMMECR1

3.68e-03651403EFO_0008412
Diseasecholesterol in very large VLDL measurement

COBLL1 APOB PCCB

3.68e-03651403EFO_0022230
Diseasetotal lipids in small VLDL

COBLL1 APOB PCCB

4.01e-03671403EFO_0022148
Diseasetotal lipids in large VLDL

COBLL1 APOB PCCB

4.01e-03671403EFO_0022175
Diseasesquamous cell carcinoma

CYP1B1 BRCA2 HERC2

4.01e-03671403EFO_0000707
DiseaseMicrocephaly

TRAIP ORC1 DYNC1H1

4.01e-03671403C0025958
Diseasetriglycerides in very small VLDL measurement

COBLL1 APOB PCCB

4.18e-03681403EFO_0022144
Diseasetriglycerides to phosphoglycerides ratio

COBLL1 APOB PCCB

4.18e-03681403EFO_0022327
Diseasefree cholesterol in large VLDL measurement

COBLL1 APOB PCCB

4.18e-03681403EFO_0022265
Diseasecholesteryl esters to total lipids in very small VLDL percentage

COBLL1 APOB PCCB

4.72e-03711403EFO_0022259

Protein segments in the cluster

PeptideGeneStartEntry
KRQDFSLVVSTKKVP

VANGL2

481

Q9ULK5
SLVVSTKKVPFFKLS

VANGL2

486

Q9ULK5
LPKSFKRKISVVSAT

ACIN1

816

Q9UKV3
VSTLKEVKPTVFIGV

ACSBG2

306

Q5FVE4
KSSKKFDILVTTPNR

DDX52

281

Q9Y2R4
IKKPTISTAVGLVTK

ASH1L

271

Q9NR48
AKTSLAPIIVFVKVS

CACNB3

281

P54284
ETLRFISTKLPDKTV

AKAP8

416

O43823
TLTKDEKVFPRSIKT

ATP13A1

601

Q9HD20
TLEIKKFIPFSRVTS

GZMK

96

P49863
KEKFPRATAIKVTDI

BOLA3

41

Q53S33
FVNVVKSTSPVKLKT

CCNE2

331

O96020
ALEVLSKIPKVTKTS

DMXL2

1901

Q8TDJ6
KEVVRRSKKVSVPST

ANKRD17

1721

O75179
RSKKVSVPSTVISRV

ANKRD17

1726

O75179
AKLKRVTIPSNTISV

COBLL1

1096

Q53SF7
LKKKTDLSIFRTPIS

ASPM

636

Q8IZT6
TKVRVRFELKSPVKT

ATP10A

591

O60312
TVTLLRTVKPEFEKF

NPR3

321

P17342
KRKDKVSILSTFLAP

ADARB2

31

Q9NS39
IRTVKSFLSKIPSVV

RGS6

46

P49758
PKVTSRNFEKSITKL

PUM3

46

Q15397
AKKSVFPKLSTVIRE

LTN1

336

O94822
ITATIAKRKSFIGTP

MAP4K3

161

Q8IVH8
AFEIAKRIPIITSAK

MFAP3L

201

O75121
PLEFTKVKTFVSRII

MATN3

96

O15232
SIKIPVKKFSSLTET

LYSMD3

106

Q7Z3D4
VVSTKTPDRKLIFGK

GTPBP6

141

O43824
VVRSFPIASITKEKK

SBF2

941

Q86WG5
QSRAPVLTVVSKFKA

MYO19

586

Q96H55
IGDKVRVKASVTTPK

HERC2

2641

O95714
PSLKSRVTISVDKSK

IGHV4-4

81

A0A075B6R2
VKISQPKKRAETLVF

KCNJ6

191

P48051
KSKAITPKRLLTSIT

ANLN

901

Q9NQW6
PAKVAVTKTVASVLA

FSIP2

11

Q5CZC0
CPKIQIIRSSKEKTT

PLXNC1

506

O60486
PSLKSSKVRTNVTVK

PLXNC1

811

O60486
SRTLGEIPTLVFKKT

KIAA0232

771

Q92628
EIPTLVFKKTSKLES

KIAA0232

776

Q92628
FSKPIVRKKLSLSSQ

MLH3

736

Q9UHC1
ITRKFKLEPSVSLVN

PEX6

886

Q13608
KFRVPKIAEFTVTIL

NSG2

61

Q9Y328
LFKTFSRKVVVVVPN

HNRNPUL2

551

Q1KMD3
VPVKKQKTRTVFSST

NANOG

91

Q9H9S0
APDFISKIKSRIVLV

KCTD4

161

Q8WVF5
SVSKVDKISRIIFPV

GABRA3

451

P34903
SPISKTFELISVIKE

PTPRZ1

2196

P23471
FLTKTAKFKEVIPIT

PPP4R3B

241

Q5MIZ7
TKQRPVARSKIKFTT

OVOL2

96

Q9BRP0
FLPAKKTSVKETQRT

DDX31

156

Q9H8H2
KFTIDKVRKGLTVVT

HECTD4

2326

Q9Y4D8
KSVLDIVFSSITVPK

OR4D6

66

Q8NGJ1
FSPKAVTKLSVEARK

NBAS

1901

A2RRP1
SFPVAALTKEKRISV

SBF1

956

O95248
STATKITTIPNVKKI

GPRC6A

306

Q5T6X5
EATVPKVTVITRKAY

PCCB

421

P05166
TVLTTERKKRGKTVP

PRPF19

181

Q9UMS4
TVEAFKPILSTRSLK

PSMG1

246

O95456
RIKRKVAFSEITSPS

ORC1

261

Q13415
VFTIIRSRKKTVPDI

MCHR2

56

Q969V1
SPDKKLTIFKTELRV

APOB

4031

P04114
KPKQEVKFRIVTLFS

CD109

141

Q6YHK3
PVTKLQVSKSKRTLT

IGSF3

676

O75054
SPRKKSTIIISGISK

C2CD2

506

Q9Y426
LVQTTKKTPSLTKRI

BIRC8

91

Q96P09
KKTPSLTKRISDTIF

BIRC8

96

Q96P09
IKKSIFRIRESPKET

BRCA2

501

P51587
STKEVKVIVLATPFK

CRTAM

106

O95727
FLETVKRKSESSPIV

CENPC

266

Q03188
PKFRVITKIKTIGST

ADCY3

966

O60266
RPVVKVKLFTESTGV

CADPS2

421

Q86UW7
TVLKTVPFTARTAKR

FMNL2

1056

Q96PY5
RPKQEKAFSLKTIST

MTDH

481

Q86UE4
VIKTVPFTARTGKRT

FMNL1

1071

O95466
KKVVISIRGTLSPKD

DAGLA

391

Q9Y4D2
SDIRKVTSVKPLKAI

FAM110B

201

Q8TC76
VKSNSLAFIKRTPVI

DYNC1H1

111

Q14204
SKPTEKTIFILFLVI

GJB7

171

Q6PEY0
IKPKSFKVNVTLRES

CYP1B1

511

Q16678
TIQITALEKITKPFF

HEATR1

1101

Q9H583
KRVTFALTTSTAKPK

CCDC168

1351

Q8NDH2
SPKASVSLIRKISKE

CCDC168

5726

Q8NDH2
FPRKVISFLTKSVKQ

CYP3A7

241

P24462
TVCEKTITVPKGKRL

DCBLD1

66

Q8N8Z6
ILAVADKIKFTVTRP

GTF2IRD1

766

Q9UHL9
KSVITIDRIKPASVV

GRIP2

271

Q9C0E4
TKISIPAFSVTLIKK

GRAMD2B

161

Q96HH9
PAFSVTLIKKTKTAL

GRAMD2B

166

Q96HH9
VKEKPSISSSVSRLK

CEP295

2516

Q9C0D2
TVEVTKTFLPLLRKS

HSD17B2

196

P37059
VKDPSVSKSVERIFK

RPRD2

111

Q5VT52
ATKDVRIFTLKPVRK

SEH1L

241

Q96EE3
RIFTLKPVRKELTSS

SEH1L

246

Q96EE3
PVTAASTVDFLKIKK

PRR14L

1116

Q5THK1
VKKLIETFSPTESLR

PCARE

731

A6NGG8
SLKVRTRKKTVPSDV

REEP4

241

Q9H6H4
AKPLTLREVEVFKSS

OGFR

146

Q9NZT2
KGLSITTKDPRIKFT

GARIN1A

176

Q6NXP2
TKQITPYVRSIAKVK

RNF207

531

Q6ZRF8
KELKVSRTVSPKSFA

SPEF2

11

Q9C093
ISPEEKFVITTTSRK

SMCHD1

66

A6NHR9
VTRPFISSKFSSKIK

PRUNE2

3011

Q8WUY3
RKKVKFTTFTTIPPD

TMEM132C

1051

Q8N3T6
SIVKSEVFPVSKTLV

RIF1

536

Q5UIP0
VPVKKQKTRTVFSST

NANOGP8

91

Q6NSW7
IKDTSIPLKILKFSV

SORCS2

576

Q96PQ0
TRKAKTIPVQAFEVK

INPPL1

301

O15357
TVGVVDTRKKTKLIS

SETX

1316

Q7Z333
PTIVKVKSLKFATEA

TCP1

506

P17987
LVRKSFKVHVPISII

SPATA31D4

656

Q6ZUB0
KPTLKEVVIVSATRT

ACAT1

36

P24752
FAVLPVTRKEKSTII

PKHD1

3846

P08F94
SKKVTLGVVFVSLVP

RNF182

206

Q8N6D2
TESLKKIKRSVSPQT

SPAST

586

Q9UBP0
KISFKIPIKSRDTLQ

SWT1

231

Q5T5J6
TSTIKTKSSRLAKPV

PLPPR1

216

Q8TBJ4
PKKRRKTVSFSAIEV

SETD1A

1161

O15047
QKAVSTDRTSVPKIK

DZIP1

646

Q86YF9
FKITTLKTTTLAPKV

PRG4

971

Q92954
VPTRISEFEKLIQKS

SORBS2

506

O94875
SVVSFDKVKEPRKSR

SAFB

601

Q15424
SEKLTKSKVQVFLPR

SERPINB8

256

P50452
KAPITNEFRKTIKLT

AMMECR1

281

Q9Y4X0
KEVVRRSKKLSVPAS

ANKHD1

1691

Q8IWZ3
KVIPTECAIKVFKTT

RIOK3

281

O14730
TFVRDIAKTVSPEKL

TBC1D24

271

Q9ULP9
PIVVFTETTEVRKTK

UBA6

931

A0AVT1
LVRKSFKVHVPISII

SPATA31D3

656

P0C874
PAIPKVRIKTIKTSS

ZNF532

356

Q9HCE3
KKVAKIFPLSSDIVT

ZNF568

156

Q3ZCX4
ILRSSTTVKVFAKPE

CD96

256

P40200
SIAIIKPDAVISKKV

NME8

156

Q8N427
SIIKCAPSKVKIIFI

MPDZ

1416

O75970
EKQRVIFTSPIKALS

MTREX

181

P42285
TKAVTTFTITVRPKN

MYCN

291

P04198
AIPKVRIKTIKTSSG

ZNF592

371

Q92610
ITPAITRVVDFAKKL

THRB

276

P10828
STKKIPTVNRITPKT

SUGP2

251

Q8IX01
RVITEVSKVPSLSKL

EXT2

471

Q93063
GVKPVLSTKSKFRVV

UBE2O

281

Q9C0C9
KTLPTKLRDALFTVV

ZBED8

281

Q8IZ13
AFALFVKTKEVPTKR

TSTD2

56

Q5T7W7
KPVSSVKERFVLKLT

ZNF518A

1411

Q6AHZ1
PSDLRTIQTFVKKAK

PHF23

81

Q9BUL5
VIHVPFIIISSSKKT

TFDP3

251

Q5H9I0
PRITISKKTKLVTLS

PRO0628

36

Q9UI54
IITPAITRVVDFAKK

THRA

221

P10827
VRTSTNKVKCPVFVV

WDR33

111

Q9C0J8
LITQKRAVLTPFLTK

nan

96

Q6AWC8
IFRPLKFNTTSVIKI

EFTUD2

576

Q15029
FNVAVKIIDRKKTPT

TSSK2

36

Q96PF2
FRKRKLPVVSSVVKV

ZC3H14

291

Q6PJT7
VTKKVVASPRIISLA

THEG

326

Q9P2T0
FEIKTPSRVITLKAA

TBC1D2

111

Q9BYX2
AIPKTCKRKTIITVD

TMA16

166

Q96EY4
RVKTVPSLFQAKLDT

TRAIP

451

Q9BWF2
TVVRKVSVTLKEIFT

ZNF391

41

Q9UJN7
SPFTVTKKESKDILI

GARIN5B

611

Q8N5Q1
TVVFEKKILKTSLPT

NLRP14

636

Q86W24