Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	SH3 domain binding	ABI1 SHANK2 MAPT MYPN ARHGAP27	2.91e-04	143	81	5	GO:0017124
GeneOntologyMolecularFunction	cargo receptor activity	CTAGE9 MIA3 CTAGE8 TMED10	3.96e-04	85	81	4	GO:0038024
GeneOntologyMolecularFunction	cytoskeletal protein binding	GAS2L1 ABI1 TTBK1 NDEL1 MAPT IFT74 GLI1 MYPN MYO1F SNTG2 GNAS HNRNPK MTSS2	4.54e-04	1099	81	13	GO:0008092
GeneOntologyBiologicalProcess	vesicle cargo loading	CTAGE9 MIA3 SEC24C CTAGE8 CTAGE15 CTAGE6 TMED10 CTAGE4	1.34e-12	36	83	8	GO:0035459
GeneOntologyBiologicalProcess	endoplasmic reticulum to Golgi vesicle-mediated transport	CTAGE9 MIA3 SEC24C CTAGE8 CTAGE15 CTAGE6 TMED10 CTAGE4	2.53e-07	159	83	8	GO:0006888
GeneOntologyBiologicalProcess	Golgi vesicle transport	CTAGE9 MIA3 SEC24C CTAGE8 PKDCC CTAGE15 CTAGE6 TMED10 CTAGE4	8.89e-06	339	83	9	GO:0048193
GeneOntologyCellularComponent	endoplasmic reticulum exit site	CTAGE9 MIA3 SEC24C CTAGE8 CTAGE15 CTAGE6 CTAGE4	3.73e-10	42	86	7	GO:0070971
GeneOntologyCellularComponent	collagen type XI trimer	COL11A1 COL11A2	1.66e-04	5	86	2	GO:0005592
GeneOntologyCellularComponent	collagen trimer	COL8A2 COL11A1 COL11A2 CCBE1	4.79e-04	88	86	4	GO:0005581
Domain	TMEM183	TMEM183A TMEM183BP	1.59e-05	2	75	2	IPR026509
Domain	SH3	MIA3 ABI1 SHANK2 MYO1F ARHGAP27 RUSC2	2.31e-04	216	75	6	SM00326
Domain	SH3	MIA3 ABI1 SHANK2 MYO1F ARHGAP27 RUSC2	2.31e-04	216	75	6	PS50002
Domain	SH3_domain	MIA3 ABI1 SHANK2 MYO1F ARHGAP27 RUSC2	2.55e-04	220	75	6	IPR001452
Domain	Collagen	COL8A2 COL11A1 COL11A2 CCBE1	3.80e-04	85	75	4	IPR008160
Domain	Collagen	COL8A2 COL11A1 COL11A2 CCBE1	3.80e-04	85	75	4	PF01391
Domain	Fib_collagen_C	COL11A1 COL11A2	8.55e-04	11	75	2	IPR000885
Domain	COLFI	COL11A1 COL11A2	8.55e-04	11	75	2	PF01410
Domain	NC1_FIB	COL11A1 COL11A2	8.55e-04	11	75	2	PS51461
Domain	Fib_collagen_C	COL11A1 COL11A2	8.55e-04	11	75	2	PD002078
Domain	COLFI	COL11A1 COL11A2	8.55e-04	11	75	2	SM00038
Domain	Homeobox	HDX ZFHX2 ZFHX3 PBX2 BARX1	2.50e-03	234	75	5	PF00046
Domain	HOMEOBOX_1	HDX ZFHX2 ZFHX3 PBX2 BARX1	2.60e-03	236	75	5	PS00027
Domain	HOX	HDX ZFHX2 ZFHX3 PBX2 BARX1	2.65e-03	237	75	5	SM00389
Domain	HOMEOBOX_2	HDX ZFHX2 ZFHX3 PBX2 BARX1	2.74e-03	239	75	5	PS50071
Domain	Homeobox_dom	HDX ZFHX2 ZFHX3 PBX2 BARX1	2.74e-03	239	75	5	IPR001356
Domain	TSPN	COL11A1 COL11A2	3.81e-03	23	75	2	SM00210
Domain	HR1_rho-bd	CCDC120 PKN1	4.50e-03	25	75	2	IPR011072
Domain	SH3_2	MIA3 SHANK2 RUSC2	5.01e-03	86	75	3	IPR011511
Domain	SH3_2	MIA3 SHANK2 RUSC2	5.01e-03	86	75	3	PF07653
Domain	-	HDX ZFHX2 ZFHX3 PBX2 BARX1	5.61e-03	283	75	5	1.10.10.60
Domain	ZnF_U1	ZFHX2 ZFHX3	6.02e-03	29	75	2	SM00451
Domain	Znf_U1	ZFHX2 ZFHX3	6.02e-03	29	75	2	IPR003604
Domain	Kinase-like_dom	TTBK1 PI4KA PKDCC PKN1 STKLD1 WNK2 EPHA1	6.03e-03	542	75	7	IPR011009
Domain	Homeobox_CS	ZFHX2 ZFHX3 PBX2 BARX1	6.68e-03	186	75	4	IPR017970
Pathway	REACTOME_CARGO_CONCENTRATION_IN_THE_ER	CTAGE9 MIA3 SEC24C CTAGE8 TMED10	2.35e-07	36	54	5	MM15300
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	MIA3 CAD ABI1 SHANK2 SEC24C LMNB1 PI4KA G3BP2 YLPM1 PKN1 TMED10 PRRC2A WNK2 HNRNPK MTSS2	2.19e-08	963	89	15	28671696
Pubmed	Characterization and expression pattern of the novel MIA homolog TANGO.	CTAGE9 MIA3 CTAGE8	1.61e-07	5	89	3	15183315
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	MIA3 CAD SEC24C YLPM1 DVL3 GEMIN5 PRRC2A	1.63e-06	220	89	7	24550385
Pubmed	Prediction of the coding sequences of mouse homologues of FLJ genes: the complete nucleotide sequences of 110 mouse FLJ-homologous cDnas identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	COL8A2 ATXN7L2 RASAL3 MYO1F GEMIN5	2.73e-06	85	89	5	15449545
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GAS2L1 CAD ABI1 NDEL1 SHANK2 SEC24C MAPT AJM1 PI4KA G3BP2 GEMIN5 PRRC2A WNK2 HNRNPK SYNCRIP	3.32e-06	1431	89	15	37142655
Pubmed	Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice.	CTAGE9 MIA3 CTAGE8	4.55e-06	13	89	3	11839810
Pubmed	Inactivation of a Gα(s)-PKA tumour suppressor pathway in skin stem cells initiates basal-cell carcinogenesis.	GLI1 GNAS	6.48e-06	2	89	2	25961504
Pubmed	Exon-Trapping Assay Improves Clinical Interpretation of COL11A1 and COL11A2 Intronic Variants in Stickler Syndrome Type 2 and Otospondylomegaepiphyseal Dysplasia.	COL11A1 COL11A2	6.48e-06	2	89	2	33348901
Pubmed	Immature osteoblastic cells express the pro-alpha2(XI) collagen gene during bone formation in vitro and in vivo.	COL11A1 COL11A2	6.48e-06	2	89	2	11780999
Pubmed	Origination and evolution of a human-specific transmembrane protein gene, c1orf37-dup.	TMEM183A TMEM183BP	6.48e-06	2	89	2	16644869
Pubmed	Requirement for Nudel and dynein for assembly of the lamin B spindle matrix.	NDEL1 LMNB1	6.48e-06	2	89	2	19198602
Pubmed	Differential in situ expression of alpha2(XI) collagen mRNA isoforms in the developing mouse.	COL11A1 COL11A2	6.48e-06	2	89	2	9560475
Pubmed	The human alpha 2(XI) collagen gene (COL11A2) maps to the centromeric border of the major histocompatibility complex on chromosome 6.	COL11A1 COL11A2	6.48e-06	2	89	2	2591970
Pubmed	Immunohistochemical localization of collagen type XI alpha1 and alpha2 chains in human colon tissue.	COL11A1 COL11A2	6.48e-06	2	89	2	18040076
Pubmed	Ultrastructural localization of collagen types II, IX, and XI in the growth plate of human rib and fetal bovine epiphyseal cartilage: type XI collagen is restricted to thin fibrils.	COL11A1 COL11A2	6.48e-06	2	89	2	7560887
Pubmed	Collagen XI sequence variations in nonsyndromic cleft palate, Robin sequence and micrognathia.	COL11A1 COL11A2	6.48e-06	2	89	2	12673280
Pubmed	Tau-tubulin kinase 1 enhances prefibrillar tau aggregation and motor neuron degeneration in P301L FTDP-17 tau-mutant mice.	TTBK1 MAPT	6.48e-06	2	89	2	20354135
Pubmed	Alternative mRNA processing occurs in the variable region of the pro-alpha 1(XI) and pro-alpha 2(XI) collagen chains.	COL11A1 COL11A2	6.48e-06	2	89	2	7721876
Pubmed	Acute inhibition of the CNS-specific kinase TTBK1 significantly lowers tau phosphorylation at several disease relevant sites.	TTBK1 MAPT	6.48e-06	2	89	2	32255788
Pubmed	Novel pathogenic COL11A1/COL11A2 variants in Stickler syndrome detected by targeted NGS and exome sequencing.	COL11A1 COL11A2	6.48e-06	2	89	2	25240749
Pubmed	Identification of DeltaNp63alpha protein interactions by mass spectrometry.	CAD SEC24C HNRNPK SYNCRIP	7.15e-06	48	89	4	20085233
Pubmed	Proteomic analysis of an interactome for long-form AMPA receptor subunits.	CAD HNRNPK SYNCRIP	7.21e-06	15	89	3	20131911
Pubmed	Genetic mapping of 20 novel expressed sequence tags from midgestation mouse embryos suggests chromosomal clustering.	TLE1 PKDCC WNK2	1.52e-05	19	89	3	9070936
Pubmed	Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.	G3BP2 MYPN GEMIN5 GNAS PBX2 PRRC2A SYNCRIP	1.93e-05	321	89	7	32098917
Pubmed	Association Between COL5a1, COL11a1, and COL11a2 Gene Variations and Rotator Cuff Tendinopathy in Young Athletes.	COL11A1 COL11A2	1.94e-05	3	89	2	34009784
Pubmed	Tau-tubulin kinase 1 (TTBK1), a neuron-specific tau kinase candidate, is involved in tau phosphorylation and aggregation.	TTBK1 MAPT	1.94e-05	3	89	2	16923168
Pubmed	Declining lamin B1 expression mediates age-dependent decreases of hippocampal stem cell activity.	LMNB1 GLI1	1.94e-05	3	89	2	33631115
Pubmed	Col11a1 and Col11a2 mRNA expression in the developing mouse cochlea: implications for the correlation of hearing loss phenotype with mutant type XI collagen genotype.	COL11A1 COL11A2	1.94e-05	3	89	2	15141750
Pubmed	The Association of Variants within Types V and XI Collagen Genes with Knee Joint Laxity Measurements.	COL11A1 COL11A2	1.94e-05	3	89	2	36553626
Pubmed	GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer.	CAD LMNB1 G3BP2 SMARCD2 TMED10 PRRC2A	2.42e-05	223	89	6	33731348
Pubmed	WWP2 ubiquitylates RNA polymerase II for DNA-PK-dependent transcription arrest and repair at DNA breaks.	CAD ABI1 SEC24C G3BP2 SMARCD2 GNAS PRRC2A HNRNPK SYNCRIP	2.88e-05	615	89	9	31048545
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	SHANK2 LMNB1 MAPT AJM1 PRRC2A HNRNPK	2.95e-05	231	89	6	16452087
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	ABI1 SHANK2 MAPT AJM1 G3BP2 PRRC2A RUSC2	3.17e-05	347	89	7	17114649
Pubmed	Collagen XI chain misassembly in cartilage of the chondrodysplasia (cho) mouse.	COL11A1 COL11A2	3.87e-05	4	89	2	17683922
Pubmed	cTAGE5 mediates collagen secretion through interaction with TANGO1 at endoplasmic reticulum exit sites.	MIA3 SEC24C	3.87e-05	4	89	2	21525241
Pubmed	Behavioral abnormalities observed in Zfhx2-deficient mice.	ZFHX2 ZFHX3	3.87e-05	4	89	2	23300874
Pubmed	RNA helicase EIF4A1-mediated translation is essential for the GC response.	EIF4H CD79A	3.87e-05	4	89	2	38011999
Pubmed	TANGO1 facilitates cargo loading at endoplasmic reticulum exit sites.	MIA3 SEC24C	3.87e-05	4	89	2	19269366
Pubmed	Mea6 controls VLDL transport through the coordinated regulation of COPII assembly.	CTAGE9 CTAGE8	3.87e-05	4	89	2	27311593
Pubmed	MEA6 Deficiency Impairs Cerebellar Development and Motor Performance by Tethering Protein Trafficking.	CTAGE9 CTAGE8	3.87e-05	4	89	2	31244610
Pubmed	miR-219-5p inhibits tau phosphorylation by targeting TTBK1 and GSK-3β in Alzheimer's disease.	TTBK1 MAPT	3.87e-05	4	89	2	30556160
Pubmed	Reduced cholesterol and triglycerides in mice with a mutation in Mia2, a liver protein that localizes to ER exit sites.	CTAGE9 CTAGE8	3.87e-05	4	89	2	21807889
Pubmed	Long non-coding RNA 00507/miRNA-181c-5p/TTBK1/MAPT axis regulates tau hyperphosphorylation in Alzheimer's disease.	TTBK1 MAPT	3.87e-05	4	89	2	32891070
Pubmed	Deletion of Mea6 in Cerebellar Granule Cells Impairs Synaptic Development and Motor Performance.	CTAGE9 CTAGE8	3.87e-05	4	89	2	33718348
Pubmed	Specific expression and regulation of the new melanoma inhibitory activity-related gene MIA2 in hepatocytes.	CTAGE9 CTAGE8	3.87e-05	4	89	2	12586826
Pubmed	Analysis of IFT74 as a candidate gene for chromosome 9p-linked ALS-FTD.	MAPT IFT74	3.87e-05	4	89	2	17166276
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	CAD MYPN GEMIN5 SMARCD2 PKN1 PRRC2A HNRNPK EPHA1	4.59e-05	503	89	8	16964243
Pubmed	SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.	CAD LMNB1 G3BP2 YLPM1 GEMIN5 GNAS PRRC2A HNRNPK SYNCRIP	4.70e-05	655	89	9	35819319
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	CAD ABI1 G3BP2 YLPM1 HNRNPK	4.91e-05	154	89	5	16055720
Pubmed	Neuronal delivery of Hedgehog directs spatial patterning of taste organ regeneration.	MAPT GLI1	6.44e-05	5	89	2	29279401
Pubmed	cTAGE: a cutaneous T cell lymphoma associated antigen family with tumor-specific splicing.	CTAGE9 CTAGE4	6.44e-05	5	89	2	12839582
Pubmed	Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.	CTAGE9 CTAGE8	6.44e-05	5	89	2	18630941
Pubmed	Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry.	CTAGE9 CTAGE8	6.44e-05	5	89	2	19131326
Pubmed	Mea6/cTAGE5 cooperates with TRAPPC12 to regulate PTN secretion and white matter development.	CTAGE9 CTAGE8	6.44e-05	5	89	2	38439956
Pubmed	Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124).	COL11A2 PKDCC	6.44e-05	5	89	2	19097194
Pubmed	A tissue-specific atlas of mouse protein phosphorylation and expression.	CTAGE9 CTAGE8	6.44e-05	5	89	2	21183079
Pubmed	BTB-ZF factors recruit the E3 ligase cullin 3 to regulate lymphoid effector programs.	LMNB1 HNRNPK SYNCRIP	6.91e-05	31	89	3	23086144
Pubmed	Nuclear heterogeneous nuclear ribonucleoprotein D is associated with poor prognosis and interactome analysis reveals its novel binding partners in oral cancer.	G3BP2 SMARCD2 HNRNPK SYNCRIP	7.93e-05	88	89	4	26318153
Pubmed	Stickler Syndrome	COL11A1 COL11A2	9.65e-05	6	89	2	20301479
Pubmed	Regulation of collagen fibril nucleation and initial fibril assembly involves coordinate interactions with collagens V and XI in developing tendon.	COL11A1 COL11A2	9.65e-05	6	89	2	21467034
Pubmed	The pro-alpha3(V) collagen chain. Complete primary structure, expression domains in adult and developing tissues, and comparison to the structures and expression domains of the other types V and XI procollagen chains.	COL11A1 COL11A2	9.65e-05	6	89	2	10722718
Pubmed	Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation.	MAPT PKN1	9.65e-05	6	89	2	9546672
Pubmed	Deletion of Pax1 scoliosis-associated regulatory elements leads to a female-biased tail abnormality.	COL11A1 COL11A2	9.65e-05	6	89	2	38461417
Pubmed	Developmental pattern of expression of the mouse alpha 1 (XI) collagen gene (Col11a1).	COL11A1 COL11A2	9.65e-05	6	89	2	8563024
Pubmed	The collagen family members as cell adhesion proteins.	COL11A1 COL11A2	9.65e-05	6	89	2	17876790
Pubmed	The role of sequence variations within the genes encoding collagen II, IX and XI in non-syndromic, early-onset osteoarthritis.	COL11A1 COL11A2	9.65e-05	6	89	2	15922184
Pubmed	Inactivation of patched1 in murine chondrocytes causes spinal fusion without inflammation.	GLI1 CD79A	9.65e-05	6	89	2	24757136
Pubmed	The molecular chaperone Hsp47 is essential for cartilage and endochondral bone formation.	COL11A1 COL11A2	9.65e-05	6	89	2	22492985
Pubmed	ISLET1-Dependent β-Catenin/Hedgehog Signaling Is Required for Outgrowth of the Lower Jaw.	GLI1 BARX1 FOXF2	9.99e-05	35	89	3	28069742
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	EIF4H MAPT G3BP2 YLPM1 DVL3 GEMIN5 SMARCD2 PRRC2A HNRNPK	1.01e-04	724	89	9	36232890
Pubmed	WWP2-WWP1 ubiquitin ligase complex coordinated by PPM1G maintains the balance between cellular p73 and ΔNp73 levels.	G3BP2 PRRC2A HNRNPK SYNCRIP	1.16e-04	97	89	4	25071155
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	CAD LMNB1 EIF4H TLE1 YLPM1 CCDC120 GNAS PRRC2A FOXF2 SYNCRIP	1.25e-04	922	89	10	27609421
Pubmed	Selective export of human GPI-anchored proteins from the endoplasmic reticulum.	SEC24C TMED10	1.35e-04	7	89	2	20427317
Pubmed	cTAGE5 deletion in pancreatic β cells impairs proinsulin trafficking and insulin biogenesis in mice.	CTAGE9 CTAGE8	1.35e-04	7	89	2	29133483
Pubmed	FoxF1 and FoxL1 link hedgehog signaling and the control of epithelial proliferation in the developing stomach and intestine.	GLI1 BARX1	1.35e-04	7	89	2	19049965
Pubmed	Regulation of Sox9 by Sonic Hedgehog (Shh) is essential for patterning and formation of tracheal cartilage.	NOG GLI1	1.35e-04	7	89	2	20034104
Pubmed	KCTD9 inhibits the Wnt/β-catenin pathway by decreasing the level of β-catenin in colorectal cancer.	CAD LMNB1 HNRNPK SYNCRIP	1.52e-04	104	89	4	36055981
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	MIA3 CAD ABI1 SHANK2 MAPT AJM1 PI4KA G3BP2 DVL3 PCK2 WNK2	1.57e-04	1139	89	11	36417873
Pubmed	RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.	CAD YLPM1 GEMIN5 PRRC2A HNRNPK	1.76e-04	202	89	5	24639526
Pubmed	The pro-alpha2(XI) collagen gene is expressed in odontoblasts.	COL11A1 COL11A2	1.79e-04	8	89	2	20059976
Pubmed	Noggin null allele mice exhibit a microform of holoprosencephaly.	NOG GLI1	1.79e-04	8	89	2	21821669
Pubmed	Identification of methylated proteins by protein arginine N-methyltransferase 1, PRMT1, with a new expression cloning strategy.	HNRNPK SYNCRIP	1.79e-04	8	89	2	12183049
Pubmed	Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.	MAPT ARHGAP27	1.79e-04	8	89	2	20070850
Pubmed	Genetic basis for an evolutionary shift from ancestral preaxial to postaxial limb polarity in non-urodele vertebrates.	NOG GLI1	1.79e-04	8	89	2	34610275
Pubmed	p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment.	NDEL1 MAPT	1.79e-04	8	89	2	11517264
Pubmed	Identification of a heterogeneous nuclear ribonucleoprotein-recognition region in the HIV Rev protein.	HNRNPK SYNCRIP	1.79e-04	8	89	2	19808671
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	TMEM183A G3BP2 YLPM1 TMEM183BP PRRC2A WNK2 SYNCRIP	1.88e-04	462	89	7	31138677
Pubmed	Defining the membrane proteome of NK cells.	MIA3 CAD RASAL3 LMNB1 EIF4H PI4KA GEMIN5 GNAS PRRC2A HNRNPK SYNCRIP	1.95e-04	1168	89	11	19946888
Pubmed	Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening.	TMEM74B SHANK2 G3BP2 SMARCD2 WNK2 FOXF2	2.06e-04	329	89	6	17474147
Pubmed	Lysosomal Signaling Licenses Embryonic Stem Cell Differentiation via Inactivation of Tfe3.	LMNB1 ZFHX2 ZFHX3 RRAGB HNRNPK SYNCRIP	2.16e-04	332	89	6	30595499
Pubmed	Misexpression of MIA disrupts lung morphogenesis and causes neonatal death.	CTAGE9 CTAGE8	2.30e-04	9	89	2	18342301
Pubmed	The SH2/SH3 adaptor Grb4 transduces B-ephrin reverse signals.	ABI1 HNRNPK	2.30e-04	9	89	2	11557983
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	CAD SEC24C LMNB1 GNAS TMED10 HNRNPK SYNCRIP	2.50e-04	484	89	7	31995728
Pubmed	Human transcription factor protein interaction networks.	CAD ATXN7L2 TLE1 G3BP2 YLPM1 SMARCD2 ZFHX3 TMED10 SSBP4 PBX2 PRRC2A SYNCRIP	2.82e-04	1429	89	12	35140242
Pubmed	Pbx loss in cranial neural crest, unlike in epithelium, results in cleft palate only and a broader midface.	PBX2 BARX1	2.88e-04	10	89	2	29797482
Pubmed	Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases.	MAPT PKN1	2.88e-04	10	89	2	9199504
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	MIA3 ABI1 EIF4H G3BP2 CTAGE8 GEMIN5 SMARCD2 TMED10 HNRNPK	3.23e-04	847	89	9	35235311
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	CAD SEC24C LMNB1 EIF4H G3BP2 DVL3 CCDC120 GNAS PRRC2A HNRNPK SYNCRIP	3.41e-04	1247	89	11	27684187
Pubmed	Primary cilia regulate Shh activity in the control of molar tooth number.	GLI1 BARX1	3.51e-04	11	89	2	19211681
Pubmed	The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma.	GLI1 GNAS	3.51e-04	11	89	2	25150496
Interaction	CTAGE1 interactions	MIA3 CTAGE8 CTAGE15 CTAGE6 CTAGE4	2.60e-10	10	83	5	int:CTAGE1
Interaction	HOMER3 interactions	MIA3 ABI1 GGN MYPN DVL3 CCDC120 PKN1	1.80e-06	140	83	7	int:HOMER3
Interaction	MIA2 interactions	MIA3 SEC24C CTAGE8 CTAGE15 CTAGE6 CTAGE4	7.22e-06	113	83	6	int:MIA2
Interaction	FXR1 interactions	MIA3 CAD ABI1 DMRT2 SEC24C MAPT CCBE1 GLI1 G3BP2 PRRC2A HNRNPK RUSC2	2.11e-05	679	83	12	int:FXR1
Cytoband	Ensembl 112 genes in cytogenetic band chr7q35	CTAGE8 CTAGE15 CTAGE6 CTAGE4 EPHA1	1.99e-07	66	89	5	chr7q35
Cytoband	7q35	CTAGE8 CTAGE15 CTAGE6 CTAGE4	4.17e-06	55	89	4	7q35
GeneFamily	CTAGE family	CTAGE9 CTAGE8 CTAGE15 CTAGE6 CTAGE4	4.29e-10	15	51	5	907
GeneFamily	Collagens	COL8A2 COL11A1 COL11A2	2.95e-04	46	51	3	490
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZFHX2 ZFHX3	8.00e-04	15	51	2	529
ToppCell	10x5'-blood-Lymphocytic_Invariant-Inducer-like-ILC3\|blood / Manually curated celltypes from each tissue	GAS2L1 TLE1 HDX PKDCC MTSS2	1.91e-05	165	88	5	f012a27ece54c0f7b73a2f4f89c6ee8b865f8782
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_CPZ\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CTAGE9 CCBE1 ZFHX3 CTAGE6 B4GALNT3	2.68e-05	177	88	5	57033ee0d49a4a50fc25328a4a44d4de2b35f505
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL11A1 COL11A2 ZFHX3 MN1 RUSC2	3.14e-05	183	88	5	1464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCell	E16.5-samps-Mesenchymal-Myofibroblast\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COL11A1 NOG SNTG2 FOXF2 SMPX	3.40e-05	186	88	5	e044b3428b7eacfdc72d0f57cdabaa1de04c74cd
ToppCell	Children_(3_yrs)-Mesenchymal-pericyte_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TMEM74B TLE1 ZFHX3 WNK2 FOXF2	3.48e-05	187	88	5	86250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	NOG PKDCC SNTG2 ZFHX3 FOXF2	3.57e-05	188	88	5	3004e961d214919e08c7cd5f10c3de5cf85b35a3
ToppCell	facs-Skin-Anagen-3m-Epithelial\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARGE2 DVL3 GNAS HNRNPK EPHA1	3.76e-05	190	88	5	888ded899f0513d41bf655896d59ae8ef74e0978
ToppCell	facs-Skin-Anagen-3m\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LARGE2 DVL3 GNAS HNRNPK EPHA1	3.76e-05	190	88	5	3466cebab16964e94da130d0673fa32e7d90b5ed
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NR2E3 COL11A1 CCBE1 BARX1 SMPX	3.85e-05	191	88	5	cc9a6a8fad17d6e1a08a68ab7512ae06b1249051
ToppCell	10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NR2E3 COL11A1 CCBE1 BARX1 SMPX	3.85e-05	191	88	5	c16b920ee69ea8536e020ac3475abf1ce972c1e6
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL8A2 COL11A1 COL11A2 NOG B4GALNT3	3.85e-05	191	88	5	f9a46956778a8773d6656340ecf5d218376d79c2
ToppCell	(07)_Ionocytes-(0)_Reference\|(07)_Ionocytes / shred by cell type by condition	LARGE2 EIF4H CTAGE15 CTAGE6 PRRC2A	4.36e-05	196	88	5	4ac33e7d11b8b0fff6ee2e9dacad49c21d63b818
ToppCell	droplet-Trachea-nan-3m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL11A1 COL11A2 KLHL21 PANK1 MTSS2	4.46e-05	197	88	5	8786125b669d5d0b15e12df0ade6b319f09f7333
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL11A1 COL11A2 KLHL21 PANK1 MTSS2	4.57e-05	198	88	5	3575620db5aeaeb0bdcd7a8ff65c43abd3fa13e4
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL8A2 COL11A1 COL11A2 ZFHX3 MN1	4.68e-05	199	88	5	edd5300da1a3b758210ff8f949e9d1988b8bc7e2
Disease	Fibrochondrogenesis	COL11A1 COL11A2	6.90e-06	2	78	2	C0265282
Disease	Stickler syndrome (implicated_via_orthology)	COL11A1 COL11A2	6.90e-06	2	78	2	DOID:0080046 (implicated_via_orthology)
Disease	Stickler syndrome	COL11A1 COL11A2	6.86e-05	5	78	2	cv:C0265253
Disease	hearing impairment	COL11A2 ARSB MN1 SMPX	1.35e-04	98	78	4	C1384666
Disease	ovarian carcinoma, COVID-19	MAPT ARHGAP27	3.74e-04	11	78	2	EFO_0001075, MONDO_0100096
Disease	advanced glycosylation end product-specific receptor, soluble measurement	B4GALNT3 PBX2	5.28e-04	13	78	2	EFO_0020131
Disease	anthropometric measurement	COL11A1 MIA3 PKDCC BARX1	1.04e-03	168	78	4	EFO_0004302
Disease	Osteoarthritis of hip	COL11A1 MAPT	1.27e-03	20	78	2	C0029410
Disease	Nonsyndromic Deafness	COL11A2 MYO1F SMPX	1.31e-03	81	78	3	C3711374
Disease	advanced glycosylation end product-specific receptor ligand measurement	B4GALNT3 PBX2	1.40e-03	21	78	2	EFO_0010762
Disease	vital capacity	NOG DMRT2 MAPT MYPN MYO1F PKDCC SMARCD2 TPRX2 ZFHX3 SSBP4	1.52e-03	1236	78	10	EFO_0004312
Disease	breast cancer, COVID-19	MAPT STKLD1	1.54e-03	22	78	2	MONDO_0007254, MONDO_0100096
Disease	peak expiratory flow	COL11A1 COL11A2 NOG MYPN B4GALNT3 MN1	2.07e-03	498	78	6	EFO_0009718

Protein segments in the cluster

Peptide	Gene	Start	Entry
VRMLTPLGPGPFSPD	EPHA1	516	P21709
FSIVTMPGPRGPAPP	BEST2	481	Q8NFU1
FPVDTRGPFMRRGPP	CTAGE4	706	Q8IX94
FPPPPPGTMFGASRG	CTAGE4	721	Q8IX94
FPVDTRGPFMRRGPP	CTAGE6	706	Q86UF2
FPPPPPGTMFGASRG	CTAGE6	721	Q86UF2
FPVDTRGPFMRRGPP	CTAGE8	706	P0CG41
FPPPPPGTMFGASRG	CTAGE8	721	P0CG41
FPVDTRGPFMRRGPP	CTAGE9	706	A4FU28
FPPPPPGTMFGASRG	CTAGE9	721	A4FU28
FPVDTRGPFMRRGPP	CTAGE15	706	A4D2H0
FPPPPPGTMFGASRG	CTAGE15	721	A4D2H0
SRLLSMVPGPARPPG	C19orf48	16	Q6RUI8
LPQMRGPRPRPAGDS	B4GALNT3	541	Q6L9W6
PSEELSGPSPRRMGG	AJM1	311	C9J069
PPSPPMSGRGTLGRN	ABI1	181	Q8IZP0
RAGGPGAGPRTPPMT	C19orf84	136	I3L1E1
RQPPPRPFLDMGEGT	CD79A	126	P11912
PSELPPPMERTGGIG	DVL3	96	Q92997
PPMERTGGIGDSRPP	DVL3	101	Q92997
DPGLFPFPMPRGGTQ	ATXN7L2	366	Q5T6C5
PRPKGSLSMGPAPRA	RASAL3	836	Q86YV0
APAGRSPRGPTPMSA	NR2E3	151	Q9Y5X4
RAGAPGCFPGPLMPR	LARGE2	41	Q8N3Y3
MPRSRGGRAAPGPPP	MMP24	1	Q9Y5R2
MDERLLGPPPPGGGR	PBX2	1	P40425
TGPPMGSRFRDGPPL	EIF4H	176	Q15056
LMGIEVPPPRGGPAD	HDX	496	Q7Z353
PAGVSGMAFPRPKRP	MAGED4	241	Q96JG8
PVPPRMGSRAGGPTT	LMNB1	6	P20700
MQRPGEPGAARFGPP	BARX1	1	Q9HBU1
SRRDGLLTMLPGPPP	CCDC120	476	Q96HB5
MPPPTRIPSAGERSG	CCDC120	536	Q96HB5
ALRGPPGPMGLTGRP	COL11A1	526	P12107
PPHMPPPTRGRGRGG	SYNCRIP	436	O60506
PFSMGPVGSPLSRIG	PCK2	161	Q16822
GPSGEEAPRPRMSPA	MTSS2	416	Q765P7
GAPGPPGTSLMLPFR	COL11A2	441	P13942
PERGMPPPSSPGGSA	PI4KA	266	P42356
RGGMIPHPQSRGPFP	GLI1	161	P08151
PGPGLRPQGTPAMRA	PRR25	111	Q96S07
FPGSATPPGLMVPRE	GGN	51	Q86UU5
RLGGLPGPGPMSNPR	DERPC	146	P0CG12
SRGIGLPGPNPSPMS	DERPC	321	P0CG12
MPPGTARPGSRGCPI	IFT74	41	Q96LB3
GPCPRMRPRPSTGLA	KLHL21	271	Q9UJP4
GGTFPLPPPVSDRMR	DMRT2	221	Q9Y5R5
ETAPAPGTPARGPRM	GAS2L1	186	Q99501
PGTPARGPRMTPSDL	GAS2L1	191	Q99501
GFPPRGPRPGRGDME	G3BP2	301	Q9UN86
PPGFSRMGKAGPPGL	COL8A2	116	P25067
MVPPPPSRGGAARGQ	CCBE1	1	Q6UXH8
MGPRGAASLPRGPGP	ARSB	1	P15848
PGAPFPMNRSSGTPG	C1orf159	121	Q96HA4
PASGGPRLPSMTGPL	SEC24C	216	P53992
PGFMATSPPEDRPGG	NOG	76	Q13253
SRGPRTAPPAPGMGD	PANK1	126	Q8TE04
HPPPGDLLPRRMGGS	MN1	636	Q10571
MTTEGGPPPAPLRRA	FOXF2	1	Q12947
EGPAAMAGPGSPPRR	RUSC2	526	Q8N2Y8
RLMDLAPGGPGLPRP	PKDCC	86	Q504Y2
PGMRPPLGLREFAPG	MIA3	1806	Q5JRA6
MARGPGPLGRPRPDT	TMEM183BP	1	Q1AE95
FDRMPPGRGGRPMPP	HNRNPK	261	P61978
PALMEPGAFSGARPG	GNAS	136	Q5JWF2
EMQPGLSPGSPGDPR	ARHGAP27	341	Q6ZUM4
RFPRVAGPRGSGPPM	PRRC2A	281	P48634
AGPRGSGPPMRLVEP	PRRC2A	286	P48634
MGTEGPPPPAASRGR	SNTG2	1	Q9NY99
PSMGGPGTPDSRPPF	PKN1	346	Q16512
MPARPGFPSSPAPGS	SLF2	6	Q8IX21
PFGAAAPLRPGMPPT	SMARCD2	96	Q92925
DVGLGPPAPRTRPSM	SHANK2	1111	Q9UPX8
MPRAGRAPAEGGPAP	PAK6-AS1	1	Q8N910
PGLPGSLEMGPLTFR	ZNF273	26	Q14593
MPTPGTSATPGLRPG	TLE1	326	Q04724
SELPMGPGLPRDPRA	TTLL8	791	A6PVC2
RDELGPSFPMASPPG	TMEM74B	16	Q9NUR3
RGMGVPSSPVRAPPD	TTBK1	426	Q5TCY1
FGRGSGGSMPPPLRV	ZFHX2	2476	Q9C0A1
MARGPGPLGRPRPDT	TMEM183A	1	Q8IXX5
MSGLSGPPARRGPFP	TMED10	1	P49755
PTQGERGPGSPGEPM	STKLD1	11	Q8NE28
PMGAFRPGAGQPPRR	SMPX	21	Q9UHP9
PFMSPRFPGGPRPTL	SSBP4	146	Q9BWG4
RFPGGPRPTLRMPSQ	SSBP4	151	Q9BWG4
GRANFPLGPGPEGPM	SSBP4	301	Q9BWG4
PVPPMSLGGEGDRPS	GEMIN5	481	Q8TEQ6
SGMPGAPLLPEGPRE	MAPT	151	P10636
GPRMDPPLGEPEGSL	RRAGB	16	Q5VZM2
LPSAPGAPRRRGSMP	REM2	56	Q8IYK8
CGSRPPPGFPGLETM	CAD	1696	P27708
DMPVRSGGLLPDPPR	YLPM1	736	P49750
MRRPPPLGPTTASGP	TOPAZ1	1	Q8N9V7
TAPRAGVGMPRLPPA	WNK2	2211	Q9Y3S1
PDPRGPRAMEGPLGV	PVRIG	311	Q6DKI7
ALPRDRTPAPGGTMP	WWC2-AS2	136	Q96NR7
PDPVLGRTLMPGPGS	TPRX2	216	P0DV77
GRTLMPGPGSLPTPA	TPRX2	221	P0DV77
LAPGGGSEPSMLPPR	ZFHX3	1921	Q15911
IMSGGGTHRPPRGPP	MYO1F	971	O00160
IPPPMSVRPSGSRYG	MYPN	1271	Q86TC9
PPGLGSSRPSSAPGM	NDEL1	326	Q9GZM8