Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	nuclear retinoid X receptor binding	NR4A2 NCOR1 FUS	1.01e-05	23	37	3	GO:0046965
GeneOntologyMolecularFunction	nuclear retinoic acid receptor binding	NR4A2 NCOR1 FUS	1.44e-04	55	37	3	GO:0042974
GeneOntologyMolecularFunction	DNA-binding transcription factor binding	NR4A2 SETD1A NCOR1 HES1 FUS RUNX2	6.43e-04	582	37	6	GO:0140297
GeneOntologyMolecularFunction	RNA polymerase II-specific DNA-binding transcription factor binding	NR4A2 SETD1A NCOR1 HES1 FUS	9.75e-04	417	37	5	GO:0061629
GeneOntologyMolecularFunction	nuclear thyroid hormone receptor binding	NCOR1 FUS	1.81e-03	34	37	2	GO:0046966
GeneOntologyMolecularFunction	chromatin binding	NCOR1 HES1 CHD7 FUS RUNX2 ZIC2	2.20e-03	739	37	6	GO:0003682
GeneOntologyMolecularFunction	transcription factor binding	NR4A2 SETD1A NCOR1 HES1 FUS RUNX2	2.41e-03	753	37	6	GO:0008134
GeneOntologyMolecularFunction	histone deacetylase binding	NCOR1 HES1 RUNX2	2.53e-03	147	37	3	GO:0042826
GeneOntologyBiologicalProcess	diencephalon development	NR4A2 NCOR1 HES1 OGDH	2.23e-05	90	38	4	GO:0021536
GeneOntologyBiologicalProcess	adult locomotory behavior	NR4A2 EPS8 CHD7 CNTN2	6.05e-05	116	38	4	GO:0008344
GeneOntologyBiologicalProcess	cellular response to magnesium ion	ANK3 RYR3	9.19e-05	8	38	2	GO:0071286
GeneOntologyBiologicalProcess	cell maturation	NR4A2 HES1 RUNX2 ANK3 CNTN2	1.24e-04	267	38	5	GO:0048469
GeneOntologyBiologicalProcess	brain development	NR4A2 SETD1A NCOR1 HES1 CHD7 OGDH CNTN2 ZIC2	1.41e-04	859	38	8	GO:0007420
GeneOntologyBiologicalProcess	locomotory behavior	NR4A2 NCOR1 EPS8 CHD7 CNTN2	1.65e-04	284	38	5	GO:0007626
GeneOntologyBiologicalProcess	protein localization to axon	ANK3 CNTN2	1.80e-04	11	38	2	GO:0099612
GeneOntologyBiologicalProcess	head development	NR4A2 SETD1A NCOR1 HES1 CHD7 OGDH CNTN2 ZIC2	2.24e-04	919	38	8	GO:0060322
GeneOntologyBiologicalProcess	stem cell differentiation	SETD1A HES1 RUNX2 FN1 ZIC2	2.34e-04	306	38	5	GO:0048863
GeneOntologyBiologicalProcess	forebrain development	NR4A2 NCOR1 HES1 CHD7 OGDH CNTN2	2.50e-04	489	38	6	GO:0030900
GeneOntologyBiologicalProcess	cell morphogenesis	NR4A2 DLG1 EPS8 HES1 SLC11A2 FN1 ANK3 CNTN2 ZIC2	2.51e-04	1194	38	9	GO:0000902
GeneOntologyBiologicalProcess	hemopoiesis	SETD1A NCOR1 HES1 CHD7 SLC11A2 RUNX2 CD19 PRRC2C PPP4R2	3.00e-04	1223	38	9	GO:0030097
GeneOntologyBiologicalProcess	neuron maturation	NR4A2 ANK3 CNTN2	3.42e-04	74	38	3	GO:0042551
GeneOntologyBiologicalProcess	cell morphogenesis involved in neuron differentiation	NR4A2 HES1 SLC11A2 FN1 ANK3 CNTN2 ZIC2	3.79e-04	748	38	7	GO:0048667
GeneOntologyBiologicalProcess	thalamus development	NCOR1 OGDH	3.90e-04	16	38	2	GO:0021794
GeneOntologyBiologicalProcess	neuronal ion channel clustering	ANK3 CNTN2	4.42e-04	17	38	2	GO:0045161
GeneOntologyBiologicalProcess	anatomical structure maturation	NR4A2 HES1 RUNX2 ANK3 CNTN2	4.56e-04	354	38	5	GO:0071695
GeneOntologyBiologicalProcess	hematopoietic progenitor cell differentiation	SETD1A HES1 PRRC2C PPP4R2	4.62e-04	197	38	4	GO:0002244
GeneOntologyBiologicalProcess	adult behavior	NR4A2 EPS8 CHD7 CNTN2	5.17e-04	203	38	4	GO:0030534
GeneOntologyCellularComponent	node of Ranvier	DLG1 ANK3 CNTN2	6.18e-06	20	38	3	GO:0033268
GeneOntologyCellularComponent	chromatin	NR4A2 SETD1A NCOR1 HES1 SINHCAF CHD7 RUNX2 ZC3H6 EBF3 PPP4R2	2.32e-04	1480	38	10	GO:0000785
GeneOntologyCellularComponent	paranode region of axon	DLG1 ANK3	4.30e-04	17	38	2	GO:0033270
GeneOntologyCellularComponent	main axon	DLG1 ANK3 CNTN2	5.65e-04	89	38	3	GO:0044304
Domain	SH3_1	DLG1 EPS8 SNX33	4.48e-03	164	38	3	PF00018
Domain	SANT	NCOR1 CHD7	4.64e-03	50	38	2	SM00717
Domain	SANT/Myb	NCOR1 CHD7	5.01e-03	52	38	2	IPR001005
Domain	SH3	DLG1 EPS8 SNX33	9.55e-03	216	38	3	PS50002
Domain	SH3	DLG1 EPS8 SNX33	9.55e-03	216	38	3	SM00326
Domain	SH3_domain	DLG1 EPS8 SNX33	1.00e-02	220	38	3	IPR001452
Domain	RRM	TNRC6B SETD1A FUS	1.13e-02	230	38	3	PS50102
Pathway	REACTOME_NRCAM_INTERACTIONS	DLG1 CNTN2	9.76e-05	7	31	2	M27378
Pathway	PID_HES_HEY_PATHWAY	NCOR1 HES1 RUNX2	1.56e-04	48	31	3	M288
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TNRC6B DLG1 NCOR1 CHD7 FUS ILF3 ANK3 EBF3 PRRC2C ZIC2	7.76e-08	963	39	10	28671696
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	TNRC6B NCOR1 EPS8 SNX33 ILF3 FN1 PRRC2C	8.94e-07	475	39	7	31040226
Pubmed	Identification of putative target genes of the transcription factor RUNX2.	BIRC3 RUNX2	1.23e-06	2	39	2	24349465
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	TNRC6B CHD7 ILF3 FLG2 USP42 OGDH ZC3H6 EBF3 DDX42	2.41e-06	1082	39	9	38697112
Pubmed	HDAC3 is a critical negative regulator of long-term memory formation.	NR4A2 NCOR1	7.34e-06	4	39	2	21228185
Pubmed	HES1 cooperates with pRb to activate RUNX2-dependent transcription.	HES1 RUNX2	7.34e-06	4	39	2	16753023
Pubmed	The vitamin D receptor, Runx2, and the Notch signaling pathway cooperate in the transcriptional regulation of osteopontin.	HES1 RUNX2	7.34e-06	4	39	2	16195230
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	ANKRD13A SETD1A CHD7 ABCA4 AGAP9 USP42 OGDH SLCO2B1 DDX42	7.39e-06	1242	39	9	30973865
Pubmed	ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.	DLG1 EPS8 FUS ILF3 FLG2 OGDH DDX42	7.79e-06	660	39	7	32780723
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	NR4A2 ANKRD13A NCOR1 EPS8 SNX33 USP42 ZC3H6	1.03e-05	689	39	7	36543142
Pubmed	Sonic Hedgehog Is a Remotely Produced Cue that Controls Axon Guidance Trans-axonally at a Midline Choice Point.	CNTN2 ZIC2	1.22e-05	5	39	2	29346753
Pubmed	Id4, a new candidate gene for senile osteoporosis, acts as a molecular switch promoting osteoblast differentiation.	HES1 RUNX2	1.22e-05	5	39	2	20628571
Pubmed	Characterization of two evolutionarily conserved, alternatively spliced nuclear phosphoproteins, NFAR-1 and -2, that function in mRNA processing and interact with the double-stranded RNA-dependent protein kinase, PKR.	FUS ILF3	1.22e-05	5	39	2	11438536
Pubmed	Gbx2 is essential for maintaining thalamic neuron identity and repressing habenular characters in the developing thalamus.	HES1 EBF3 CNTN2	1.25e-05	40	39	3	26297811
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	NCOR1 CHD7 FUS ILF3 DDX42	1.58e-05	283	39	5	30585729
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	NCOR1 CHD7 FUS ILF3 RUNX2 EBF3 PRRC2C PPP4R2	2.56e-05	1103	39	8	34189442
Pubmed	HERP, a novel heterodimer partner of HES/E(spl) in Notch signaling.	NCOR1 HES1	2.56e-05	7	39	2	11486045
Pubmed	Deletion of cIAP1 and cIAP2 in murine B lymphocytes constitutively activates cell survival pathways and inactivates the germinal center response.	BIRC3 CD19	2.56e-05	7	39	2	21300983
Pubmed	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.	TNRC6B DLG1 NCOR1 EPS8 CHD7 AGAP9	2.76e-05	536	39	6	15840001
Pubmed	Exchangeable gene trap using the Cre/mutated lox system.	TNRC6B DLG1 NCOR1 EPS8 CHD7 AGAP9	2.82e-05	538	39	6	10512203
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TNRC6B DLG1 SETD1A NCOR1 ANK3 PRRC2C	3.16e-05	549	39	6	38280479
Pubmed	Distinct adhesive behaviors of neurons and neural precursor cells during regional differentiation in the mammalian forebrain.	FN1 CNTN2	3.42e-05	8	39	2	7750641
Pubmed	ARIH2 Is a Vif-Dependent Regulator of CUL5-Mediated APOBEC3G Degradation in HIV Infection.	TNRC6B NCOR1 FUS ILF3 RUNX2	3.59e-05	336	39	5	31253590
Pubmed	PABP1 identified as an arginine methyltransferase substrate using high-density protein arrays.	FUS ILF3	4.39e-05	9	39	2	11850402
Pubmed	Apical expansion of calvarial osteoblasts and suture patency is dependent on fibronectin cues.	RUNX2 FN1	4.39e-05	9	39	2	38602508
Pubmed	Prostate tumor OVerexpressed-1 (PTOV1) down-regulates HES1 and HEY1 notch targets genes and promotes prostate cancer progression.	NCOR1 HES1	4.39e-05	9	39	2	24684754
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	SINHCAF CHD7 RUNX2 FLG2 EBF3 ZIC2	4.41e-05	583	39	6	29844126
Pubmed	Iron deficiency alters expression of genes implicated in Alzheimer disease pathogenesis.	SLC11A2 FN1	5.48e-05	10	39	2	18723004
Pubmed	Recruitment of IkappaBalpha to the hes1 promoter is associated with transcriptional repression.	NCOR1 HES1	5.48e-05	10	39	2	15536134
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	NR4A2 FUS ANK3 RYR3	6.24e-05	191	39	4	20195357
Pubmed	The Hedgehog receptor Patched1 regulates proliferation, neurogenesis, and axon guidance in the embryonic spinal cord.	HES1 CNTN2	6.70e-05	11	39	2	31634536
Pubmed	A role for Nr-CAM in the patterning of binocular visual pathways.	CNTN2 ZIC2	8.03e-05	12	39	2	16701205
Pubmed	Transient and lineage-restricted requirement of Ebf3 for sternum ossification.	RUNX2 EBF3	8.03e-05	12	39	2	32398354
Pubmed	Control of the migratory pathway of facial branchiomotor neurones.	EBF3 CNTN2	9.48e-05	13	39	2	11076752
Pubmed	Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins.	FUS ILF3	9.48e-05	13	39	2	17765891
Pubmed	Creld1 regulates myocardial development and function.	HES1 FN1	9.48e-05	13	39	2	33773996
Pubmed	Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem.	NR4A2 EBF3	9.48e-05	13	39	2	22421355
Pubmed	Temporal patterning of apical progenitors and their daughter neurons in the developing neocortex.	FN1 ANK3 CNTN2	1.09e-04	82	39	3	31073041
Pubmed	NOVA2-mediated RNA regulation is required for axonal pathfinding during development.	NR4A2 CNTN2	1.11e-04	14	39	2	27223325
Pubmed	Ablation of CNTN2+ Pyramidal Neurons During Development Results in Defects in Neocortical Size and Axonal Tract Formation.	NR4A2 CNTN2	1.11e-04	14	39	2	31749685
Pubmed	DSCAM promotes axon fasciculation and growth in the developing optic pathway.	CNTN2 ZIC2	1.11e-04	14	39	2	28137836
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	MPLKIP TNRC6B CHD7 SNX33 ILF3 FLG2 FN1 PRRC2C	1.18e-04	1371	39	8	36244648
Pubmed	Satb2 is required for the regionalization of retrosplenial cortex.	NR4A2 FN1	1.27e-04	15	39	2	31666685
Pubmed	Parvins Are Required for Endothelial Cell-Cell Junctions and Cell Polarity During Embryonic Blood Vessel Formation.	HES1 FN1	1.27e-04	15	39	2	29567677
Pubmed	Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse.	NR4A2 EBF3	1.27e-04	15	39	2	25762221
Pubmed	Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation.	RUNX2 FN1	1.27e-04	15	39	2	38018454
Pubmed	Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in mice.	HES1 CHD7	1.27e-04	15	39	2	19855134
Pubmed	A systematic, genome-wide, phenotype-driven mutagenesis programme for gene function studies in the mouse.	CHD7 ZIC2	1.46e-04	16	39	2	10932191
Pubmed	TRIM30 modulates Interleukin-22-regulated papillary thyroid Cancer cell migration and invasion by targeting Sox17 for K48-linked Polyubiquitination.	ILF3 FLG2	1.46e-04	16	39	2	31823782
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DLG1 EPS8 ILF3 FN1 ANK3 OGDH PRRC2C CNTN2	1.59e-04	1431	39	8	37142655
Pubmed	Interactome analyses revealed that the U1 snRNP machinery overlaps extensively with the RNAP II machinery and contains multiple ALS/SMA-causative proteins.	NCOR1 FUS ILF3 DDX42	1.60e-04	244	39	4	29884807
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	TNRC6B FUS ILF3 FN1 PRRC2C	1.61e-04	462	39	5	31138677
Pubmed	A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular development.	CHD7 RYR3	1.65e-04	17	39	2	26102480
Pubmed	Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality.	NR4A2 CNTN2	1.65e-04	17	39	2	24441682
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	DLG1 NCOR1 FUS ILF3 OGDH SLCO2B1 PRRC2C DDX42	1.67e-04	1442	39	8	35575683
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	DLG1 SINHCAF CHD7 FN1 ANK3 PPP4R2 DDX42	1.80e-04	1084	39	7	11544199
Pubmed	Fibronectin isoforms promote postnatal skeletal development.	RUNX2 FN1	1.85e-04	18	39	2	39159790
Pubmed	A systematic study of nuclear interactome of C-terminal domain small phosphatase-like 2 using inducible expression system and shotgun proteomics.	FUS ILF3	1.85e-04	18	39	2	26674342
Pubmed	Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development.	HES1 CPA5	1.85e-04	18	39	2	12921743
Pubmed	RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells.	HES1 RUNX2	1.85e-04	18	39	2	15689374
Pubmed	Tbx1 and Foxi3 genetically interact in the pharyngeal pouch endoderm in a mouse model for 22q11.2 deletion syndrome.	HES1 FN1	1.85e-04	18	39	2	31412026
Pubmed	Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant.	DLG1 FUS FLG2 FN1 PRRC2C	2.07e-04	488	39	5	31324722
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	DLG1 NCOR1 CHD7 SNX33 ILF3 USP42	2.08e-04	774	39	6	15302935
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	TNRC6B DLG1 NCOR1 FLG2 FN1 ANK3	2.12e-04	777	39	6	35844135
Pubmed	Prediction of the coding sequences of unidentified human genes. XIV. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	TNRC6B NCOR1 PRRC2C	2.20e-04	104	39	3	10470851
Pubmed	Cux2 functions downstream of Notch signaling to regulate dorsal interneuron formation in the spinal cord.	HES1 CNTN2	2.30e-04	20	39	2	19542352
Pubmed	Genome-wide meta-analyses of nonsyndromic cleft lip with or without cleft palate identify six new risk loci.	ABCA4 ZIC2	2.30e-04	20	39	2	22863734
Pubmed	T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities.	NR4A2 NCOR1	2.30e-04	20	39	2	11877444
Pubmed	PRDM16 determines specification of ventricular cardiomyocytes by suppressing alternative cell fates.	CNTN2 RYR3	2.54e-04	21	39	2	39304345
Pubmed	Interaction proteomics of canonical Caspr2 (CNTNAP2) reveals the presence of two Caspr2 isoforms with overlapping interactomes.	DLG1 CNTN2	2.54e-04	21	39	2	25707359
Pubmed	Suppressor of Fused restraint of Hedgehog activity level is critical for osteogenic proliferation and differentiation during calvarial bone development.	HES1 RUNX2	2.54e-04	21	39	2	28794157
Pubmed	Hes1 and Hes3 regulate maintenance of the isthmic organizer and development of the mid/hindbrain.	NR4A2 HES1	2.54e-04	21	39	2	11500373
Pubmed	Importance of EGFR/ERCC1 interaction following radiation-induced DNA damage.	FUS ILF3	2.79e-04	22	39	2	24780295
Pubmed	Mechanical load regulates bone growth via periosteal Osteocrin.	RUNX2 FN1	2.79e-04	22	39	2	34260913
Pubmed	Jagged1 is essential for osteoblast development during maxillary ossification.	HES1 RUNX2	2.79e-04	22	39	2	24491691
Pubmed	Composition and three-dimensional EM structure of double affinity-purified, human prespliceosomal A complexes.	FUS ILF3 DDX42	2.95e-04	115	39	3	17332742
Pubmed	Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation.	HES1 RUNX2	3.05e-04	23	39	2	18297083
Pubmed	Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis.	FUS FN1 PRRC2C	3.51e-04	122	39	3	29530978
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	TNRC6B NCOR1 PRRC2C	3.59e-04	123	39	3	26912792
Pubmed	Lmx1b controls the differentiation and migration of the superficial dorsal horn neurons of the spinal cord.	EBF3 ZIC2	3.62e-04	25	39	2	15229182
Pubmed	Notch pathway regulation of chondrocyte differentiation and proliferation during appendicular and axial skeleton development.	HES1 RUNX2	3.91e-04	26	39	2	19590010
Pubmed	LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli.	HES1 ZIC2	3.91e-04	26	39	2	26439398
Pubmed	Tissue-specific regulation of retinal and pituitary precursor cell proliferation.	NCOR1 HES1	3.91e-04	26	39	2	12130660
Pubmed	Adamts18 modulates the development of the aortic arch and common carotid artery.	HES1 FN1	3.91e-04	26	39	2	34189436
Pubmed	Regulation of differentiation flux by Notch signalling influences the number of dopaminergic neurons in the adult brain.	NR4A2 HES1	3.91e-04	26	39	2	26912775
Pubmed	Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST.	DLG1 ANK3 OGDH	4.04e-04	128	39	3	30995482
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	TNRC6B DLG1 NCOR1 FUS ILF3 RUNX2 ZC3H6	4.21e-04	1247	39	7	27684187
Pubmed	Integrative genomic analysis of early neurogenesis reveals a temporal genetic program for differentiation and specification of preplate and Cajal-Retzius neurons.	EBF3 ZIC2	4.23e-04	27	39	2	33760820
Pubmed	Activation of PI3K/p110α in the Lung Mesenchyme Affects Branching Morphogenesis and Club Cell Differentiation.	HES1 FN1	4.55e-04	28	39	2	35676931
Pubmed	Novel genes differentially expressed in cortical regions during late neurogenesis.	NR4A2 EBF3	4.55e-04	28	39	2	17614941
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	NCOR1 EPS8 CHD7 PRRC2C PPP4R2	4.86e-04	588	39	5	38580884
Pubmed	Shp2-dependent ERK signaling is essential for induction of Bergmann glia and foliation of the cerebellum.	HES1 CNTN2	4.88e-04	29	39	2	24431450
Pubmed	An isoform of retinoid-related orphan receptor β directs differentiation of retinal amacrine and horizontal interneurons.	NR4A2 EBF3	4.88e-04	29	39	2	23652001
Pubmed	Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells.	HES1 RUNX2	4.88e-04	29	39	2	25535917
Pubmed	Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.	CHD7 ZIC2	4.88e-04	29	39	2	23396134
Pubmed	Identifying and quantifying in vivo methylation sites by heavy methyl SILAC.	FUS ILF3	5.23e-04	30	39	2	15782174
Pubmed	Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors.	NR4A2 HES1	5.23e-04	30	39	2	21880902
Pubmed	Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex.	FN1 CNTN2	5.23e-04	30	39	2	18055048
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	NCOR1 SINHCAF CHD7 FUS ILF3 USP42 DDX42	5.26e-04	1294	39	7	30804502
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	FUS ILF3 FLG2 PRRC2C DDX42	5.53e-04	605	39	5	28977666
Interaction	CA2 interactions	BIRC3 FUS USP42 PRRC2C	1.12e-05	74	38	4	int:CA2
Interaction	MECP2 interactions	TNRC6B NCOR1 CHD7 FUS ILF3 FLG2 USP42 OGDH ZC3H6 EBF3 DDX42	1.67e-05	1287	38	11	int:MECP2
Interaction	YAP1 interactions	TNRC6B DLG1 SETD1A NCOR1 FUS RUNX2 FLG2 ANK3 OGDH PRRC2C	2.52e-05	1095	38	10	int:YAP1
Interaction	NUP50 interactions	BIRC3 DLG1 SETD1A NCOR1 CHD7 DDX42	3.93e-05	341	38	6	int:NUP50
Interaction	TIAM1 interactions	DLG1 ILF3 ANK3 RYR3 DDX42	3.96e-05	205	38	5	int:TIAM1
Interaction	IGF2BP1 interactions	BIRC3 NCOR1 SINHCAF FUS ILF3 FN1 PRRC2C	3.98e-05	508	38	7	int:IGF2BP1
Interaction	TCERG1 interactions	BIRC3 SETD1A FUS FN1 DDX42	4.15e-05	207	38	5	int:TCERG1
Interaction	XRCC6 interactions	BIRC3 NCOR1 EPS8 CHD7 FUS ILF3 RUNX2 FN1 DDX42	4.37e-05	928	38	9	int:XRCC6
Interaction	SF3B3 interactions	BIRC3 NCOR1 EPS8 FUS ILF3 PPP4R2 DDX42	7.19e-05	558	38	7	int:SF3B3
Interaction	SFPQ interactions	NR4A2 BIRC3 FUS ILF3 FN1 PRRC2C DDX42	7.61e-05	563	38	7	int:SFPQ
Interaction	RBBP4 interactions	BIRC3 SETD1A NCOR1 SINHCAF CHD7 FUS FN1	8.49e-05	573	38	7	int:RBBP4
Interaction	SUPT5H interactions	BIRC3 NCOR1 CHD7 FUS FN1 PPP4R2	1.06e-04	408	38	6	int:SUPT5H
Interaction	WWTR1 interactions	TNRC6B DLG1 NCOR1 RUNX2 ANK3 PRRC2C	1.27e-04	422	38	6	int:WWTR1
Interaction	NUP35 interactions	TNRC6B BIRC3 NCOR1 FUS ILF3 PRRC2C	1.31e-04	424	38	6	int:NUP35
Interaction	ATP5F1B interactions	BIRC3 CHD7 FUS ILF3 FN1 OGDH PRRC2C	1.50e-04	628	38	7	int:ATP5F1B
Interaction	PRPF19 interactions	BIRC3 SETD1A FUS FN1 PPP4R2 DDX42	1.81e-04	450	38	6	int:PRPF19
Interaction	CAPRIN1 interactions	TNRC6B BIRC3 FUS ILF3 PRRC2C PPP4R2	1.83e-04	451	38	6	int:CAPRIN1
Interaction	FUBP3 interactions	TNRC6B BIRC3 FUS FN1 PRRC2C	2.26e-04	297	38	5	int:FUBP3
Interaction	UBAP2L interactions	TNRC6B BIRC3 FUS FN1 PRRC2C	2.30e-04	298	38	5	int:UBAP2L
Interaction	NUPR1 interactions	DLG1 EPS8 FUS ILF3 FLG2 OGDH DDX42	2.51e-04	683	38	7	int:NUPR1
Interaction	SF1 interactions	MPLKIP BIRC3 FUS ILF3 FN1	2.52e-04	304	38	5	int:SF1
Interaction	NANOG interactions	NCOR1 SINHCAF CHD7 ILF3 USP42 ZIC2	2.59e-04	481	38	6	int:NANOG
Interaction	SNRPA interactions	BIRC3 FUS ILF3 FN1 PRRC2C DDX42	2.62e-04	482	38	6	int:SNRPA
Interaction	PRKDC interactions	BIRC3 SETD1A NCOR1 SINHCAF FUS ILF3 FN1	2.79e-04	695	38	7	int:PRKDC
Interaction	AMOT interactions	TNRC6B BIRC3 DLG1 FUS USP42	2.84e-04	312	38	5	int:AMOT
Interaction	PABPC1 interactions	TNRC6B BIRC3 SINHCAF FUS ILF3 FN1 PRRC2C	2.89e-04	699	38	7	int:PABPC1
Interaction	ENO1 interactions	BIRC3 NCOR1 FUS FN1 ANK3 OGDH RYR3	2.94e-04	701	38	7	int:ENO1
Interaction	PHF5A interactions	BIRC3 SETD1A PPP4R2 DDX42	2.95e-04	171	38	4	int:PHF5A
Interaction	CHD4 interactions	BIRC3 SETD1A FUS ILF3 FLG2 PRRC2C PPP4R2 DDX42	3.01e-04	938	38	8	int:CHD4
Interaction	DDX6 interactions	TNRC6B BIRC3 ILF3 FN1 PRRC2C DDX42	3.29e-04	503	38	6	int:DDX6
Interaction	DDX21 interactions	BIRC3 SINHCAF FUS ILF3 RUNX2 FN1 PRRC2C	3.41e-04	718	38	7	int:DDX21
Interaction	RPS20 interactions	TNRC6B BIRC3 FUS ILF3 FN1 PRRC2C	3.65e-04	513	38	6	int:RPS20
Interaction	PSPC1 interactions	BIRC3 DLG1 FUS ILF3 PRRC2C DDX42	3.73e-04	515	38	6	int:PSPC1
Interaction	KCNC1 interactions	DLG1 ANK3	4.09e-04	16	38	2	int:KCNC1
Interaction	HDAC4 interactions	TNRC6B NCOR1 EPS8 SNX33 ILF3 RUNX2 PRRC2C	4.22e-04	744	38	7	int:HDAC4
Interaction	DIMT1 interactions	BIRC3 ILF3 FN1 USP42	4.31e-04	189	38	4	int:DIMT1
Interaction	SF3B4 interactions	MPLKIP FUS ILF3 PPP4R2 DDX42	4.33e-04	342	38	5	int:SF3B4
Interaction	FMR1 interactions	TNRC6B DLG1 NCOR1 CHD7 ILF3 PRRC2C	4.61e-04	536	38	6	int:FMR1
Interaction	SF3B6 interactions	ILF3 FN1 PPP4R2 DDX42	4.76e-04	194	38	4	int:SF3B6
Interaction	PHB2 interactions	BIRC3 NCOR1 ILF3 RUNX2 FN1 OGDH	4.79e-04	540	38	6	int:PHB2
Interaction	TARS1 interactions	BIRC3 FUS FN1 OGDH	4.85e-04	195	38	4	int:TARS1
Interaction	EIF3A interactions	BIRC3 NCOR1 ILF3 FN1 PRRC2C	5.13e-04	355	38	5	int:EIF3A
Interaction	HIVEP3 interactions	FUS RUNX2	5.20e-04	18	38	2	int:HIVEP3
Interaction	DUXB interactions	CHD7 FLG2	5.20e-04	18	38	2	int:DUXB
Interaction	C6 interactions	FUS FN1	5.20e-04	18	38	2	int:C6
Interaction	RALY interactions	BIRC3 ABCA4 FUS ILF3 FN1	5.20e-04	356	38	5	int:RALY
Interaction	HSPD1 interactions	BIRC3 FUS ILF3 RUNX2 FN1 OGDH PRRC2C RYR3	5.34e-04	1022	38	8	int:HSPD1
Interaction	HNRNPDL interactions	BIRC3 FUS ILF3 FN1 PRRC2C	5.75e-04	364	38	5	int:HNRNPDL
Cytoband	16p11.2	SETD1A FUS CD19	5.80e-04	191	39	3	16p11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr16p11	SETD1A FUS CD19	1.71e-03	278	39	3	chr16p11
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	NCOR1 CHD7	3.04e-03	53	28	2	532
GeneFamily	Ankyrin repeat domain containing	ANKRD13A AGAP9 ANK3	6.06e-03	242	28	3	403
Coexpression	SENESE_HDAC1_TARGETS_UP	BIRC3 DLG1 SINHCAF FUS FN1 OGDH DDX42	4.07e-06	451	39	7	M14973
Coexpression	SENESE_HDAC3_TARGETS_UP	NR4A2 BIRC3 SINHCAF FUS FN1 OGDH DDX42	7.49e-06	495	39	7	M8451
Coexpression	GSE29617_CTRL_VS_DAY3_TIV_FLU_VACCINE_PBMC_2008_UP	NR4A2 ILF3 USP42 EBF3 PRRC2C	1.04e-05	196	39	5	M4928
Coexpression	GSE29618_BCELL_VS_PDC_UP	NR4A2 BIRC3 HES1 CHD7 CD19	1.04e-05	196	39	5	M4940
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	NR4A2 TNRC6B NCOR1 SINHCAF ILF3 PRRC2C	6.14e-05	467	39	6	M1347
Coexpression	SCHAEFFER_PROSTATE_DEVELOPMENT_6HR_DN	NR4A2 TNRC6B NCOR1 SINHCAF ILF3 PRRC2C	7.48e-05	484	39	6	MM999
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	NCOR1 SINHCAF CHD7 ANK3 PRRC2C PPP4R2	1.30e-08	185	39	6	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	(03)_KRT6B+-(2)_GFP_FOXI1\|(03)_KRT6B+ / shred by cell type by condition	TNRC6B BIRC3 NCOR1 EPS8 SLC11A2 PRRC2C	2.01e-08	199	39	6	c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_moDC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	NR4A2 TNRC6B DLG1 SNX33 FUS	6.04e-07	187	39	5	0099def970fbc828756fbf853eca2ce77b8cd342
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	NR4A2 BIRC3 HES1 CHD7 CD19	7.05e-07	193	39	5	bbea475d2c4c7b29674ff302529f8f83dd666dcb
ToppCell	368C-Lymphocytic-B_cell-\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NR4A2 ANKRD13A HES1 SINHCAF CD19	7.23e-07	194	39	5	9a72b6a3217b100617f468aaad48566a04334f3c
ToppCell	368C-Lymphocytic-B_cell\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NR4A2 ANKRD13A HES1 SINHCAF CD19	7.23e-07	194	39	5	f8c46c5855a684ed5cb5289da4c29cf3e6052b97
ToppCell	severe-B_intermediate\|severe / disease stage, cell group and cell class	NR4A2 ANKRD13A BIRC3 HES1 CD19	7.61e-07	196	39	5	8f59e51ca50bef4753f67cd1efdb02665805a120
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNRC6B BIRC3 CHD7 ANK3 PRRC2C	8.00e-07	198	39	5	a3bd099ef0e606c2da690a6fcf6f79e9360c9c9f
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Myeloid\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	EPS8 HES1 USP42 SLCO2B1 PRRC2C	8.41e-07	200	39	5	cc8368665bc6bb7c4f39632ccff07ceaa98a7b65
ToppCell	Parenchymal-10x3prime_v2-Immune_Myeloid-Myeloid-Megakaryocyte\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	EPS8 HES1 USP42 SLCO2B1 PRRC2C	8.41e-07	200	39	5	0d76b006d8e8b32174e65e400acd0674354b962c
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8\|Lung / Manually curated celltypes from each tissue	TNRC6B FUS ANK3 PRRC2C	9.15e-06	151	39	4	999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCell	normal_Pleural_Fluid-B_lymphocytes-Undetermined\|normal_Pleural_Fluid / Location, Cell class and cell subclass	TNRC6B BIRC3 CHD7 CD19	1.15e-05	160	39	4	5744cd30709f38e84f7ec8893dc19d7a288b465a
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-early_pro_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HES1 SLC11A2 CD19 SLCO2B1	1.60e-05	174	39	4	4cdf2eedc28d88d18241ee390092426fdf849e79
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-early_pro-B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HES1 SLC11A2 CD19 SLCO2B1	1.60e-05	174	39	4	268be5e7d2a18b866770b7cdb966c3958c7e6534
ToppCell	C_00\|World / shred on cell type and cluster	HES1 FUS ILF3 PRRC2C	1.79e-05	179	39	4	da2dadc3266ffebd4a34ac61bfa05fddcadcde4c
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	BIRC3 FUS ANK3 PRRC2C	1.99e-05	184	39	4	bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NR4A2 ANKRD13A SLC11A2 ANK3	2.03e-05	185	39	4	a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell	Control-B_memory-0\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	NR4A2 SINHCAF FUS ANK3	2.08e-05	186	39	4	80f6f25dbe3c5efe4bc350f5d2eb990c38aab338
ToppCell	droplet-Bladder-nan\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NR4A2 NCOR1 FUS PRRC2C	2.12e-05	187	39	4	663991a8afe652e92363b64bcbd68c14d0307f0e
ToppCell	B_cells-Naive_B_cells_\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	NR4A2 BIRC3 CHD7 CD19	2.17e-05	188	39	4	d1bc1316bbb8cfc39acc70f8680b14d19f536997
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-3\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BIRC3 SINHCAF CHD7 CD19	2.17e-05	188	39	4	cd833a125a5279ac32a9a9cb9ecd05ae24bea3a9
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-0\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BIRC3 SINHCAF CHD7 CD19	2.17e-05	188	39	4	6f53bcd4caab2fc961af799039ea5c3ddae56781
ToppCell	ILEUM-inflamed-(5)_Plasma-(5)_IgA_plasma_cells\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	TNRC6B DLG1 FUS RUNX2	2.21e-05	189	39	4	a0634d72bfdd5f93877724ed6480b50a3a046f71
ToppCell	368C-Lymphocytic-B_cell\|368C / Donor, Lineage, Cell class and subclass (all cells)	NR4A2 BIRC3 SINHCAF CD19	2.26e-05	190	39	4	b9abf773525f7bbc87b8c0d4e94e9d18017de82b
ToppCell	368C-Lymphocytic-B_cell-\|368C / Donor, Lineage, Cell class and subclass (all cells)	NR4A2 BIRC3 SINHCAF CD19	2.26e-05	190	39	4	1a016ae2603be5d024ba024faafd725787db8c48
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BIRC3 SINHCAF CHD7 CD19	2.26e-05	190	39	4	95b9334573eefb132daaa9371377ad60232006ae
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-intestinal_crypt_stem_cell\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP100 SINHCAF ILF3 PRRC2C	2.26e-05	190	39	4	52c59001a079c76249abbaa3141e9e661b83d9a0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANKRD13A BIRC3 SINHCAF CD19	2.26e-05	190	39	4	0db545a4cba7534bad2693e0d565cde7dbc7a586
ToppCell	remission-B_memory\|World / disease stage, cell group and cell class	ANKRD13A BIRC3 CHD7 CD19	2.26e-05	190	39	4	c3f55f752e47b5a71e111367cdbed4a39ab5cb21
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNRC6B BIRC3 ANK3 PRRC2C	2.30e-05	191	39	4	e94dfd2d8da81bfd16f2f1a4f3ac27b078eeb3ca
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BIRC3 HES1 CHD7 CD19	2.30e-05	191	39	4	5a9a592875fbd0b1429b48db29a760fdc9c2c856
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BIRC3 SINHCAF CHD7 CD19	2.30e-05	191	39	4	22134a2c1a92208bc1629a620ce73a56502613c2
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BIRC3 SINHCAF CHD7 CD19	2.35e-05	192	39	4	debd471f61cf3606b8e9c246add0be5df601af7f
ToppCell	Control-Lymphoid-T\|World / Disease state, Lineage and Cell class	TNRC6B BIRC3 RUNX2 ANK3	2.35e-05	192	39	4	253cf4d2cf88ad8c45b73779336180840bef054b
ToppCell	COVID-19_Mild-Lymphoid_B-B_memory\|COVID-19_Mild / Disease group, lineage and cell class	BIRC3 SINHCAF CHD7 CD19	2.35e-05	192	39	4	d27db7669de95bddbea8ccb83e6f10ae7240b1ab
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_memory\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	BIRC3 SINHCAF CHD7 CD19	2.35e-05	192	39	4	314f74dd3c6d94839eed05b9a1a398217ef78029
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-13\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BIRC3 HES1 CHD7 CD19	2.35e-05	192	39	4	e5ab932b4c2fed538161281ae07dfcdd82706fdd
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPS8 HES1 FN1 EBF3	2.40e-05	193	39	4	68089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCell	mild_COVID-19-B_memory\|World / disease group, cell group and cell class (v2)	BIRC3 SINHCAF CHD7 CD19	2.40e-05	193	39	4	69b70c838328fdc7dbb6b5449fe2811a5389a839
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANK3 PRRC2C PPP4R2 RYR3	2.40e-05	193	39	4	1aa3ab528605dc7b2fec46e759c9d1ee93d59b11
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	NR4A2 BIRC3 CHD7 CD19	2.45e-05	194	39	4	5cd72330c9d9bb21b6c9d5d35085eade101486d1
ToppCell	COVID-19_Mild-Lymphoid_B-B_intermediate\|COVID-19_Mild / Disease group, lineage and cell class	BIRC3 HES1 CHD7 CD19	2.45e-05	194	39	4	bf6f72a489c62cbf1a679552d8c5eaaaa0b99d33
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-B_cell-B_cell-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BIRC3 AGAP9 CD19 RYR3	2.45e-05	194	39	4	9a99abc65e7509e7ae8fb392f5ee4b2a83128072
ToppCell	control-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TOGARAM1 FUS RUNX2 USP42	2.50e-05	195	39	4	66959ae839eb60a573da06bdd227090ebb5bb9ed
ToppCell	severe-B_intermediate\|World / disease stage, cell group and cell class	NR4A2 BIRC3 HES1 CD19	2.50e-05	195	39	4	ce4bd004ceb05a269387adfed255d7fa393afcc6
ToppCell	normal_Lung-B_lymphocytes-Follicular_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	BIRC3 HES1 CHD7 CD19	2.50e-05	195	39	4	2a9a2b36a9a4ce72a3b855c0872214f38a7c64b0
ToppCell	severe_COVID-19-B_naive\|World / disease group, cell group and cell class (v2)	BIRC3 HES1 CHD7 CD19	2.50e-05	195	39	4	e6c77119494b787c44502c0390fb2c86a34b1846
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-midbrain/hindbrain_cells\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	ANK3 EBF3 CNTN2 ZIC2	2.55e-05	196	39	4	0767581b69bc7e6334d580ca02ed1e831b7b55da
ToppCell	3'-GW_trimst-2-LargeIntestine\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NR4A2 FUS FN1 EBF3	2.55e-05	196	39	4	27a216af92100224818c91e298428bee25ab0af8
ToppCell	Sepsis-Bac-SEP-Lymphocyte-B-B_intermediate\|Bac-SEP / Disease, condition lineage and cell class	BIRC3 CHD7 ANK3 CD19	2.55e-05	196	39	4	1611920211beb1a3691e3853e0314792a74279a0
ToppCell	moderate-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	TNRC6B FUS RUNX2 PRRC2C	2.55e-05	196	39	4	9152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	TNRC6B BIRC3 CHD7 CD19	2.55e-05	196	39	4	c225c8eb2fe9a10f0cf574c7d8b6206887aac2df
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	BIRC3 SINHCAF ANK3 PRRC2C	2.65e-05	198	39	4	8a7897d98f5296745d9005a7cd777f0a2f78000d
ToppCell	B_cells-Activate_B_cells\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	NR4A2 BIRC3 ANK3 ZC3H6	2.65e-05	198	39	4	a663082d7fbd6db11d3d3024bbb8ba00183e19f8
ToppCell	Enterocyte_Progenitors\|World / shred on cell type and cluster	HES1 FUS ILF3 PRRC2C	2.71e-05	199	39	4	776bcc887927dea9ebd76ec4338ce2225c319c2c
ToppCell	T_cells-CCR7+_T_cells\|T_cells / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	NR4A2 BIRC3 CHD7 ANK3	2.71e-05	199	39	4	467820d6abe3024d9d655b9672c2f9cdc1303db3
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-B-B_intermediate\|COVID-19_Mild / Disease, condition lineage and cell class	BIRC3 HES1 CHD7 CD19	2.71e-05	199	39	4	1c6a08d01f6c1a2a4b6587d3a4522efbd03275e1
ToppCell	Caecum-T_cell-Activated_CD4_T\|T_cell / Region, Cell class and subclass	NR4A2 BIRC3 FUS ANK3	2.71e-05	199	39	4	13173cc4dcc8e856680372b0a4ad4f36afa892c1
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW10\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	HES1 SINHCAF CHD7 FUS	2.71e-05	199	39	4	8e72efcd421639ac36ed036ee13f13de070d361f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	HES1 SINHCAF CHD7 FUS	2.76e-05	200	39	4	7c495030e6566b81d97b5516d1972e335ce5ed8c
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	HES1 SINHCAF CHD7 ZIC2	2.76e-05	200	39	4	c792d1dbbe27ebd60f4770834f30882c1a625be5
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Neuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	SINHCAF CHD7 CNTN2 ZIC2	2.76e-05	200	39	4	332905a686356cd1e024d40679be98e9d8b1b5e8
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Neuron\|2m / Sample Type, Dataset, Time_group, and Cell type.	SINHCAF CHD7 EBF3 CNTN2	2.76e-05	200	39	4	a581f1704a87b0390e1e2ff85053367d85247755
ToppCell	severe-CD4+_T_naive\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BIRC3 CHD7 ANK3 PRRC2C	2.76e-05	200	39	4	f74bdabadca8ad6dae1b6e6812c66325aac50db0
ToppCell	normal_Lymph_Node-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	NR4A2 HES1 SLCO2B1	3.22e-04	153	39	3	5424494ea1f09542799045a875cc3eac13de5079
ToppCell	(2)_NK/T-(23)_CD4+_T_cell-(230)_CD4+/CD25+_Reg_T_cell\|(23)_CD4+_T_cell / immune cells in Peripheral Blood (logTPM normalization)	BIRC3 CPA5 ZNRF2	3.28e-04	154	39	3	059bdf6843f94f5028d4df6aa025865a9edb4521
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 ANK3 CNTN2	3.41e-04	156	39	3	a4b0e89255ea5d60198cb2b3e739981f9c9cf5c5
ToppCell	droplet-Liver-LIVER_NPC-30m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RUNX2 CD19 PRRC2C	3.60e-04	159	39	3	997963d879e5819683793cddf5e1acff1b81a1b8
ToppCell	droplet-Liver-LIVER_NPC\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RUNX2 CD19 PRRC2C	3.60e-04	159	39	3	e4eaa88772835d6b78e1a18a0cec52de51e80339
ToppCell	PBMC-Control-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-1\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	BIRC3 CHD7 CD19	3.67e-04	160	39	3	7ad065337ac802de52c15ee715f6b78a3eed0cef
ToppCell	Control-B_intermediate-10\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	NR4A2 ANK3 CD19	3.81e-04	162	39	3	aa80452b972bb8ad3670ffaba4ce26fadb33b185
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	TNRC6B FUS ANK3	3.81e-04	162	39	3	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	normal_Lymph_Node-B_lymphocytes-Undetermined\|normal_Lymph_Node / Location, Cell class and cell subclass	CHD7 CD19 PRRC2C	3.81e-04	162	39	3	91ac35ae7fde411cd6a44e715a33dac62419cab8
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	CFAP100 BIRC3 RUNX2	4.02e-04	165	39	3	a379fa981db51bec01adea7b1e55e133e15ec383
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-Tfh\|bone_marrow / Manually curated celltypes from each tissue	CPA5 AGAP9 ANK3	4.09e-04	166	39	3	9ac5267d3a53a96dec9eae3bc01acba4750742c8
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CPA5 ANK3 RYR3	4.09e-04	166	39	3	5e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CPA5 ANK3 RYR3	4.09e-04	166	39	3	bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	BIRC3 ANK3 USP42	4.16e-04	167	39	3	ced6ed9b412739c6ced622523347c10295edbf53
ToppCell	10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	BIRC3 RUNX2 ANK3	4.23e-04	168	39	3	07be11b6f0f37106e219692db5795c6dd32807c9
ToppCell	COVID-19-Myeloid-MoAM5,_CCL3L1\|Myeloid / Condition, Lineage and Cell class	NR4A2 BIRC3 HES1	4.23e-04	168	39	3	ea465152ea31391b63c02425beafa9a4f51f6703
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPS8 HES1 FN1	4.38e-04	170	39	3	b5b47fe42617a4c2ebb49c8ed55db3926213a75a
ToppCell	NS-critical-d_0-4-Lymphoid-B_cell\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SINHCAF CHD7 CD19	4.46e-04	171	39	3	bd1ebd9037a740ad8c01c460d778b0973d8b56df
ToppCell	normal-na-Lymphocytic_T-T4_em-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	BIRC3 ANK3 PRRC2C	4.46e-04	171	39	3	61318a7aaf3bd8bdd28f8a8614ab4fdf2964b3a3
ToppCell	facs-Trachea-nan-24m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFAP100 RUNX2 FN1	4.61e-04	173	39	3	2226505610af1becc253d0a5550627144ef0ed6b
ToppCell	Control-CD4+_T_activated\|World / Disease group and Cell class	NR4A2 BIRC3 SETD1A	4.61e-04	173	39	3	12f8e4276b290bb388a56de4c8d8dd60415b2f63
ToppCell	severe-B_memory\|severe / disease stage, cell group and cell class	ANKRD13A BIRC3 SINHCAF	4.61e-04	173	39	3	3a987ac53a0136cc4c70ce8b901a15fc00c795e1
ToppCell	Control-CD4+_T_activated\|Control / Disease group and Cell class	NR4A2 BIRC3 SETD1A	4.69e-04	174	39	3	2b683e81b315ad22555314433aed5681feb48da8
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-10\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SETD1A HES1 CD19	4.69e-04	174	39	3	59ccc5a82507463e0a316ba6286cb25ec1a4091b
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CHD7 FUS PRRC2C	4.77e-04	175	39	3	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	P15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EBF3 SLCO2B1 RYR3	4.77e-04	175	39	3	84d252f3e432231687613299bbea14978bb4b06b
ToppCell	P15-Endothelial-lymphatic_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	EBF3 SLCO2B1 RYR3	4.77e-04	175	39	3	a00c6fa9b33640710dd05a3799031147196f0986
ToppCell	(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells\|World / Stress and Cell class	HES1 RUNX2 ANK3	4.85e-04	176	39	3	ce2c32b5ce0da848eb4da35ce4d215cdf74d9113
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPS8 RUNX2 ANK3	4.85e-04	176	39	3	3bbac5c2397535631fce8fa98f6ddb4fe0260351
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BIRC3 RUNX2 CD19	4.93e-04	177	39	3	b326376e879afef579b1b7094d756aaff0de270b
ToppCell	3'-Adult-SmallIntestine-Hematopoietic-Plasma_cells\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BIRC3 RUNX2 CD19	4.93e-04	177	39	3	393882f1bf7658a17e10a771b803339f16fb2e69
ToppCell	10x3'2.3-week_14-16-Myeloid_macrophage-stroma-monocytoid_macrophage\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	NR4A2 EPS8 SLCO2B1	5.01e-04	178	39	3	e44b0aa82890ae84fc4d1343f1c65ae2fda69a11
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-B_cell-B_cell\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NR4A2 BIRC3 CD19	5.09e-04	179	39	3	fad1fbee002fcd424c03460d695559060ce41a3f
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-B_cell\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NR4A2 BIRC3 CD19	5.09e-04	179	39	3	6d4e4b64e633b2ae8514ffa1e45829d6508dac54
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Mesenchymal-Mes\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	EPS8 HES1 ABCA4	5.09e-04	179	39	3	368f7e91e9c2c854c8778788cead022d158d1122
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-B_cell-B_cell-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	NR4A2 BIRC3 CD19	5.09e-04	179	39	3	61a7cc01fae4115325fce0efaa5bacf8f9af5ba2
Computational	Ovary genes.	NR4A2 EPS8 HES1 FN1 PPP4R2 DDX42	3.07e-04	368	28	6	MODULE_1
Computational	DRG (dorsal root ganglia) genes.	NR4A2 EPS8 HES1 FN1 ANK3 DDX42	3.86e-04	384	28	6	MODULE_2
Disease	insulin sensitivity measurement, response to polyunsaturated fatty acid supplementation	TNRC6B EPS8	8.82e-05	11	38	2	EFO_0004471, EFO_0009131
Disease	schizophrenia (implicated_via_orthology)	NR4A2 SETD1A ZIC2	9.32e-05	68	38	3	DOID:5419 (implicated_via_orthology)
Disease	iron deficiency anemia (biomarker_via_orthology)	SLC11A2 FN1	1.25e-04	13	38	2	DOID:11758 (biomarker_via_orthology)
Disease	Arthritis, Psoriatic	NR4A2 RUNX2	1.46e-04	14	38	2	C0003872
Disease	Glioblastoma	NCOR1 HES1 FN1	1.46e-04	79	38	3	C0017636
Disease	Giant Cell Glioblastoma	NCOR1 HES1 FN1	1.75e-04	84	38	3	C0334588
Disease	Malignant neoplasm of breast	MPLKIP NCOR1 HES1 ABCA4 FUS FN1 SLCO2B1	3.90e-04	1074	38	7	C0006142
Disease	Glioblastoma Multiforme	NCOR1 HES1 FN1	3.97e-04	111	38	3	C1621958
Disease	Ureteral obstruction	HES1 FN1	4.38e-04	24	38	2	C0041956
Disease	amyotrophic lateral sclerosis (is_implicated_in)	FUS SLC11A2	7.82e-04	32	38	2	DOID:332 (is_implicated_in)
Disease	orofacial cleft	ABCA4 ZIC2	1.05e-03	37	38	2	MONDO_0000358

Protein segments in the cluster

Peptide	Gene	Start	Entry
NGGGSLNNYSSSIPP	AGAP9	251	Q5VTM2
TPGESPGIVSNYNNS	ABCA4	86	P78363
NDGYAPPDITNSSSQ	DLG1	411	Q12959
GSYSNSPSNPVNSRA	BIRC3	136	Q13489
SNTPGNGLASPHSQY	CHD7	91	Q9P2D1
SGPASNGGISQTNTY	ANKRD13A	506	Q8IZ07
GYSNSSGCGRPQNAS	FLG2	281	Q5D862
YPGSYSRSPAGSQQQ	MPLKIP	86	Q8TAP9
SRSPAGSQQQFGYSP	MPLKIP	91	Q8TAP9
GQQPAPSSTSGSYGS	FUS	101	P35637
YPAETLSPGGNATQS	KIAA1109	4091	Q2LD37
NGSNSNPCSETYHGP	CPA5	281	Q8WXQ8
NISGAPVTYPSAGAQ	DDX42	771	Q86XP3
PVTYPSAGAQGVNNT	DDX42	776	Q86XP3
SASLGNINPAYSNPS	SLC11A2	21	P49281
RNTNAGAPPGTAYQS	OGDH	81	Q02218
PSYGNPSSDVQADGA	CD19	376	P15391
PSPEGTTGQSYNQYS	FN1	2431	P02751
MSSSGYPPNQGAFST	NCOR1P1	1	Q9H4R4
SNYNSPGSGQNYSGP	ILF3	856	Q12906
QGASPNAATTSGYTP	ANK3	521	Q12955
GRSPSYLSSPQQGSQ	CFAP100	336	Q494V2
YNRAGTGPASPSANA	CNTN2	891	Q02246
PSQMNGYGSSPTFSQ	EPS8	16	Q12929
SPGFLNGSSANSPYG	EBF3	506	Q9H4W6
NGSSANSPYGIVPSS	EBF3	511	Q9H4W6
PGNSPSYTERSNING	PPP4R2	156	Q9NY27
PVYTSNSGTSVGPNA	HES1	246	Q14469
AQYGSSPQGASPASQ	NR4A2	6	P43354
YPGSSQSQSGPFQTS	RUNX2	426	Q13950
MSSSGYPPNQGAFST	NCOR1	1	O75376
PSAQTPNGTDYVASG	PRRC2C	1961	Q9Y520
GSPGAQVSLYNSPSV	SNX33	76	Q8WV41
GQFTPQSSQGTPYTS	SETD1A	261	O15047
PAQSPCYSNQSDDGS	SINHCAF	131	Q9NP50
NGPSPIATASGQSEY	UHRF1BP1L	101	A0JNW5
FSIPNSSSGPYGSQD	ZNRF2	101	Q8NHG8
SDPSAYQNQPGSSEA	USP42	11	Q9H9J4
ENHCSPGSSYQQSPG	ZC3H6	566	P61129
SAPASAPSNGNCSSY	SLCO2B1	166	O94956
SVSQANQGNSYSPAP	RYR3	2706	Q15413
TSSNGQNPSPGAYIL	TOGARAM1	801	Q9Y4F4
NYGQGSPAANSSVSP	UHRF1BP1	1166	Q6BDS2
GSGFSNFNPNSNPSA	TNRC6B	296	Q9UPQ9
PGQSSAFTSQGPGAY	ZIC2	71	O95409