Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF821 DUXA ATOH7 CPHXL2 DUX4L9 ISX DUX4L2 DUX4 MEIS3 RAX2 RAX MEIS1 MEIS2 MEIS3P1 ZNF705G CRX PKNOX2 OTX1 OTX2 MIXL1 PKNOX1 TGIF2LX ZFHX3 DUX5 DUX3 DUX1 VSX2 DUX4L4

9.15e-1114599528GO:0000977
GeneOntologyMolecularFunctionDNA-binding transcription factor activity, RNA polymerase II-specific

DUXA ATOH7 CPHXL2 DUX4L9 ISX DUX4L2 DUX4 MEIS3 RAX2 RAX MEIS1 MEIS2 MEIS3P1 ZNF705G CRX PKNOX2 OTX1 OTX2 MIXL1 PKNOX1 TGIF2LX ZFHX3 DUX5 DUX3 DUX1 VSX2 DUX4L4

2.37e-1014129527GO:0000981
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF821 ATOH7 CPHXL2 DUX4 MEIS3 RAX2 CXXC1 RAX MEIS1 MEIS2 MEIS3P1 CRX PKNOX2 OTX1 OTX2 MIXL1 PKNOX1 TGIF2LX ZFHX3

7.12e-0612719519GO:0000987
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

DUX4 MEIS3 RAX2 RAX MEIS1 MEIS2 MEIS3P1 CRX OTX1 OTX2 MIXL1 DUX1

1.38e-055609512GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

DUX4 MEIS3 RAX2 RAX MEIS1 MEIS2 MEIS3P1 CRX OTX1 OTX2 MIXL1 DUX1

1.54e-055669512GO:0001216
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF821 ATOH7 CPHXL2 DUX4 MEIS3 RAX2 RAX MEIS1 MEIS2 MEIS3P1 CRX PKNOX2 OTX1 OTX2 MIXL1 PKNOX1 TGIF2LX ZFHX3

2.01e-0512449518GO:0000978
GeneOntologyMolecularFunctionnodal binding

LEFTY2 LEFTY1

6.16e-048952GO:0038100
GeneOntologyBiologicalProcessvisual system development

ATOH7 MEIS3 ITGAM RAX MEIS1 MEIS2 MEIS3P1 CRX FREM2 OTX2 ALMS1 PKNOX1 MFN2 MYOM2 CRYBG3 VSX2

4.64e-104839316GO:0150063
GeneOntologyBiologicalProcesssensory system development

ATOH7 MEIS3 ITGAM RAX MEIS1 MEIS2 MEIS3P1 CRX FREM2 OTX2 ALMS1 PKNOX1 MFN2 MYOM2 CRYBG3 VSX2

5.89e-104919316GO:0048880
GeneOntologyBiologicalProcesseye development

ATOH7 MEIS3 RAX MEIS1 MEIS2 MEIS3P1 CRX FREM2 OTX2 ALMS1 PKNOX1 MFN2 MYOM2 CRYBG3 VSX2

3.79e-094809315GO:0001654
GeneOntologyBiologicalProcesssensory organ development

ATOH7 MEIS3 RAX MEIS1 MEIS2 MEIS3P1 CRX FREM2 OTX1 OTX2 ALMS1 PKNOX1 MFN2 MYOM2 CRYBG3 VSX2

1.54e-077309316GO:0007423
GeneOntologyBiologicalProcessnegative regulation of nodal receptor complex assembly

LEFTY2 LEFTY1

2.01e-052932GO:1900124
GeneOntologyBiologicalProcessregulation of nodal receptor complex assembly

LEFTY2 LEFTY1

2.01e-052932GO:1900123
GeneOntologyBiologicalProcessnodal receptor complex assembly

LEFTY2 LEFTY1

2.01e-052932GO:0038099
GeneOntologyBiologicalProcesscamera-type eye development

ATOH7 RAX MEIS1 CRX ALMS1 PKNOX1 MFN2 MYOM2 CRYBG3 VSX2

2.23e-054269310GO:0043010
GeneOntologyBiologicalProcessembryonic pattern specification

MEIS3 MEIS1 MEIS2 MEIS3P1 OTX2

5.73e-0591935GO:0009880
GeneOntologyBiologicalProcesscell migration involved in gastrulation

LEFTY2 LEFTY1 MIXL1

9.57e-0520933GO:0042074
GeneOntologyBiologicalProcesspattern specification process

MEIS3 ITGAM RAX MEIS1 MEIS2 MEIS3P1 LEFTY2 LEFTY1 OTX1 OTX2

1.30e-045269310GO:0007389
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

ATOH7 DUX4 MEIS3 RAX2 RAX MEIS1 MEIS2 MEIS3P1 CRX OTX1 OTX2 MIXL1 PKNOX1 ZFHX3 DUX1 VSX2 AGRN

1.43e-0413909317GO:0045944
GeneOntologyBiologicalProcessdiencephalon morphogenesis

OTX1 OTX2

2.98e-046932GO:0048852
GeneOntologyBiologicalProcessnegative regulation of nodal signaling pathway

LEFTY2 LEFTY1

4.16e-047932GO:1900108
GeneOntologyBiologicalProcessregulation of low-density lipoprotein particle receptor catabolic process

ABCA2 FURIN

4.16e-047932GO:0032803
GeneOntologyBiologicalProcesslow-density lipoprotein particle receptor catabolic process

ABCA2 FURIN

4.16e-047932GO:0032802
GeneOntologyBiologicalProcesslow-density lipoprotein receptor particle metabolic process

ABCA2 FURIN

4.16e-047932GO:0032799
MousePhenomicrophthalmia

SZT2 MEIS3 CLDN12 RAX MEIS1 KIF7 BEX3 FREM2 OTX2 VSX2 CAPN15

1.06e-063626711MP:0001297
MousePhenoabnormal eye size

SZT2 MEIS3 CLDN12 RAX MEIS1 KIF7 BEX3 FREM2 OTX2 VSX2 CAPN15

1.49e-063756711MP:0002697
MousePhenoabnormal left renal vein morphology

LEFTY2 LEFTY1

2.26e-052672MP:0011327
MousePhenoabnormal renal vein morphology

LEFTY2 LEFTY1

2.26e-052672MP:0011323
MousePhenoabsent heart

LEFTY2 LEFTY1 OTX2

3.69e-0514673MP:0011388
MousePhenoabnormal circardian behavior entrainment

ATOH7 RAX ZFHX3

4.60e-0515673MP:0020476
MousePhenoabnormal circadian behavior

ATOH7 RAX MEIS1 CRX ZFHX3

5.01e-0584675MP:0020467
MousePhenosmall lens

RAX MEIS1 PKNOX1 VSX2

6.76e-0546674MP:0001306
MousePhenoabnormal kidney venous blood vessel morphology

LEFTY2 LEFTY1

6.77e-053672MP:0011311
MousePhenoabnormal orbit morphology

BEX3 OTX1 OTX2

8.16e-0518673MP:0010030
MousePhenoabnormal heart valve morphology

MRGPRD MEIS2 LEFTY2 LEFTY1 FREM2 MGP

1.27e-04163676MP:0000285
MousePhenoabnormal large intestine placement

LEFTY2 LEFTY1

1.35e-044672MP:0003284
MousePhenodecreased midbrain size

RAX OTX1 OTX2

1.74e-0423673MP:0012089
MousePhenoabnormal notochord morphology

LEFTY2 LEFTY1 OTX2 MIXL1

2.32e-0463674MP:0002825
MousePhenoabsent heart right ventricle

LEFTY2 LEFTY1

3.35e-046672MP:0003872
MousePhenoabnormal rhythmic behavior

ATOH7 GRIA3 RAX MEIS1 CRX ZFHX3

4.27e-04204676MP:0021121
MousePhenoabnormal midbrain size

RAX OTX1 OTX2

4.30e-0431673MP:0012088
MousePhenoabnormal retina pigment epithelium morphology

CRX OTX2 ALMS1 PKNOX1 VSX2

4.66e-04135675MP:0005201
MousePhenoabnormal trigeminal V mesencephalic nucleus morphology

OTX1 OTX2

4.68e-047672MP:0000906
MousePhenoabnormal bronchus morphology

LEFTY2 LEFTY1 MGP

5.18e-0433673MP:0002264
MousePhenoabnormal blood circulation

MRGPRD SZT2 CLDN12 MEIS1 MEIS2 CRX FREM2 MGP FBXO41 PKNOX1 PLAT DCBLD2

6.06e-048456712MP:0002128
MousePhenoabnormal orbitosphenoid bone morphology

OTX1 OTX2

6.22e-048672MP:0004457
MousePhenoleft atrial isomerism

LEFTY2 LEFTY1

6.22e-048672MP:0008461
DomainHomeobox

DUXA ISX DUX4 MEIS3 RAX2 RAX MEIS1 MEIS2 CRX PKNOX2 OTX1 OTX2 MIXL1 PKNOX1 TGIF2LX ZFHX3 DUX5 DUX3 DUX1 VSX2

9.40e-202349020PF00046
DomainHOX

DUXA ISX DUX4 MEIS3 RAX2 RAX MEIS1 MEIS2 CRX PKNOX2 OTX1 OTX2 MIXL1 PKNOX1 TGIF2LX ZFHX3 DUX5 DUX3 DUX1 VSX2

1.21e-192379020SM00389
DomainHOMEOBOX_2

DUXA ISX DUX4 MEIS3 RAX2 RAX MEIS1 MEIS2 CRX PKNOX2 OTX1 OTX2 MIXL1 PKNOX1 TGIF2LX ZFHX3 DUX5 DUX3 DUX1 VSX2

1.43e-192399020PS50071
DomainHomeobox_dom

DUXA ISX DUX4 MEIS3 RAX2 RAX MEIS1 MEIS2 CRX PKNOX2 OTX1 OTX2 MIXL1 PKNOX1 TGIF2LX ZFHX3 DUX5 DUX3 DUX1 VSX2

1.43e-192399020IPR001356
DomainHOMEOBOX_1

DUXA ISX MEIS3 RAX2 RAX MEIS1 MEIS2 CRX PKNOX2 OTX1 OTX2 MIXL1 PKNOX1 TGIF2LX ZFHX3 DUX5 DUX3 DUX1 VSX2

2.66e-182369019PS00027
Domain-

DUXA ISX DUX4 MEIS3 RAX2 RAX MEIS1 MEIS2 CRX PKNOX2 OTX1 OTX2 MIXL1 SSH3 PKNOX1 TGIF2LX ZFHX3 DUX5 DUX1 VSX2

4.09e-1828390201.10.10.60
DomainHomeodomain-like

DUXA ISX DUX4 MEIS3 RAX2 RAX MEIS1 MEIS2 CRX PKNOX2 OTX1 OTX2 MIXL1 SSH3 PKNOX1 TGIF2LX ZFHX3 DUX5 DUX3 DUX1 VSX2

5.25e-183329021IPR009057
DomainPKNOX/Meis_N

MEIS3 MEIS1 MEIS2 PKNOX2 PKNOX1

2.32e-125905IPR032453
DomainMeis_PKNOX_N

MEIS3 MEIS1 MEIS2 PKNOX2 PKNOX1

2.32e-125905PF16493
DomainHomeobox_KN

MEIS3 MEIS1 MEIS2 PKNOX2 PKNOX1 TGIF2LX

1.25e-1017906PF05920
DomainHomeobox_KN_domain

MEIS3 MEIS1 MEIS2 PKNOX2 PKNOX1 TGIF2LX

1.25e-1017906IPR008422
DomainHomeobox_CS

ISX RAX2 RAX CRX OTX1 OTX2 MIXL1 ZFHX3 DUX5 DUX1 VSX2

1.49e-091869011IPR017970
DomainOtx_TF_C

CRX OTX1 OTX2

1.08e-073903IPR013851
DomainTF_Otx

CRX OTX1 OTX2

1.08e-073903PF03529
DomainHTH_motif

DUXA DUX4 DUX5 DUX3 DUX1

2.05e-0569905IPR000047
DomainLRDF

LEFTY2 LEFTY1

2.30e-052902IPR003942
DomainOtx_TF

OTX1 OTX2

2.30e-052902IPR003025
DomainOAR

RAX VSX2

2.31e-0315902PF03826
DomainOAR

RAX VSX2

2.64e-0316902PS50803
DomainOAR_dom

RAX VSX2

2.64e-0316902IPR003654
Domainzf-RanBP

RNF31 CAPN15

4.98e-0322902PF00641
Domain-

ALLC FURIN DCBLD2

5.28e-03739032.60.120.260
DomainZnF_RBZ

RNF31 CAPN15

5.44e-0323902SM00547
DomainZF_RANBP2_2

RNF31 CAPN15

5.44e-0323902PS50199
Pubmed

Active genes in junk DNA? Characterization of DUX genes embedded within 3.3 kb repeated elements.

DUX4L2 DUX4 DUX5 DUX3 DUX1 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

4.18e-2217991011245978
Pubmed

Nucleotide sequence of the partially deleted D4Z4 locus in a patient with FSHD identifies a putative gene within each 3.3 kb element.

DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

1.58e-181299810433963
Pubmed

Evolutionary conservation of a coding function for D4Z4, the tandem DNA repeat mutated in facioscapulohumeral muscular dystrophy.

DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

4.11e-181399817668377
Pubmed

The DUX4 gene at the FSHD1A locus encodes a pro-apoptotic protein.

DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

9.74e-18899717588759
Pubmed

DUX4, a candidate gene of facioscapulohumeral muscular dystrophy, encodes a transcriptional activator of PITX1.

DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

1.45e-161099717984056
Pubmed

Characterization of a tandemly repeated 3.3-kb KpnI unit in the facioscapulohumeral muscular dystrophy (FSHD) gene region on chromosome 4q35.

DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

2.06e-15139977739628
Pubmed

The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells.

MEIS1 MEIS2 LEFTY2 PKNOX2 LEFTY1 OTX2 PKNOX1

4.06e-132499720826531
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

ZNF821 DUXA ATOH7 ISX MEIS3 RAX MEIS2 CRX PKNOX2 OTX1 OTX2 MIXL1 PKNOX1 TGIF2LX VSX2

4.37e-11544991528473536
Pubmed

Identification of a conserved family of Meis1-related homeobox genes.

MEIS3 MEIS1 MEIS2 MEIS3P1

6.18e-1149949049632
Pubmed

Rostral hindbrain patterning involves the direct activation of a Krox20 transcriptional enhancer by Hox/Pbx and Meis factors.

MEIS3 MEIS1 MEIS2 PKNOX2 PKNOX1

7.69e-111199518787068
Pubmed

Gene expression is dynamically regulated in retinal progenitor cells prior to and during overt cellular differentiation.

ATOH7 RAX CRX OTX1 OTX2 VSX2

1.29e-102799624148613
Pubmed

Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype.

MEIS3 MEIS1 MEIS2 PKNOX2 PKNOX1

2.13e-101399516847320
Pubmed

Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity.

ATOH7 RAX OTX1 OTX2 VSX2

2.13e-101399515576400
Pubmed

Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development.

MEIS3 MEIS1 MEIS2 PKNOX2 PKNOX1

2.13e-101399517049510
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

ISX MEIS3 TERT RAX MEIS1 MEIS2 OTX1 OTX2 PKNOX1 ZFHX3 VSX2

2.63e-10263991120932939
Pubmed

Dynamic expression of MEIS1 homeoprotein in E14.5 forebrain and differentiated forebrain-derived neural stem cells.

MEIS3 MEIS1 MEIS2 PKNOX2 PKNOX1

4.95e-101599523756022
Pubmed

A census of human transcription factors: function, expression and evolution.

ATOH7 ISX BOLA1 MEIS3 RAX2 RAX MEIS1 MEIS2 CRX PKNOX2 OTX1 OTX2 MIXL1 PKNOX1 TGIF2LX ZFHX3 VSX2

7.81e-10908991719274049
Pubmed

Meis1 coordinates a network of genes implicated in eye development and microphthalmia.

MEIS1 MEIS2 OTX1 OTX2 VSX2

1.40e-091899526253404
Pubmed

Regulation of EphA8 gene expression by TALE homeobox transcription factors during development of the mesencephalon.

MEIS3 MEIS1 MEIS2 PKNOX1

2.15e-09799417178831
Pubmed

An essential role for RAX homeoprotein and NOTCH-HES signaling in Otx2 expression in embryonic retinal photoreceptor cell fate determination.

RAX CRX OTX2 VSX2

4.29e-09899422090505
Pubmed

Meis homeoproteins directly regulate Pax6 during vertebrate lens morphogenesis.

MEIS3 MEIS1 MEIS2 PKNOX1

7.70e-09999412183364
Pubmed

GDF11 controls the timing of progenitor cell competence in developing retina.

ATOH7 RAX CRX OTX2 VSX2

8.57e-092599515976303
Pubmed

Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.

ATOH7 KDM5C DUX4L9 DUX4L2 TERT CXXC1 RAX MEIS1 MEIS2 CRX OTX1 OTX2 PKNOX1 ZFHX3 DUX4L4

9.61e-09808991520412781
Pubmed

Otx5 regulates genes that show circadian expression in the zebrafish pineal complex.

CRX OTX1 OTX2

2.24e-08399311753388
Pubmed

CRX is a diagnostic marker of retinal and pineal lineage tumors.

CRX OTX1 OTX2

2.24e-08399319936203
Pubmed

Suppressor of fused is required to maintain the multipotency of neural progenitor cells in the retina.

ATOH7 RAX CRX OTX1 VSX2

2.27e-083099521451052
Pubmed

The Gene Regulatory Network of Lens Induction Is Wired through Meis-Dependent Shadow Enhancers of Pax6.

MEIS1 MEIS2 PKNOX2 OTX2

4.33e-081399427918583
Pubmed

Deficient FGF signaling causes optic nerve dysgenesis and ocular coloboma.

ATOH7 RAX CRX OTX1 VSX2

5.93e-083699523720040
Pubmed

Otx2 homeobox gene controls retinal photoreceptor cell fate and pineal gland development.

RAX CRX OTX2 VSX2

6.05e-081499414625556
Pubmed

Characterization of a double homeodomain protein (DUX1) encoded by a cDNA homologous to 3.3 kb dispersed repeated elements.

DUX5 DUX1 DUX4L6

8.93e-0849939736770
Pubmed

QRX, a novel homeobox gene, modulates photoreceptor gene expression.

RAX2 RAX CRX

8.93e-08499315028672
Pubmed

Intracellular trafficking and dynamics of double homeodomain proteins.

DUX4 DUX5 DUX1

8.93e-08499315709750
Pubmed

The homeobox transcription factor DUXBL controls exit from totipotency.

DUX4L9 DUX4L2 DUX4L4

8.93e-08499338509386
Pubmed

Expression profiling of immature thymocytes revealed a novel homeobox gene that regulates double-negative thymocyte development.

DUX4L9 DUX4L2 DUX4L4

8.93e-08499317911620
Pubmed

Stage-dependent requirement of neuroretinal Pax6 for lens and retina development.

ATOH7 RAX CRX OTX2 VSX2

9.00e-083999524523460
Pubmed

Nodal antagonists in the anterior visceral endoderm prevent the formation of multiple primitive streaks.

LEFTY2 LEFTY1 OTX2 MIXL1

1.09e-071699412431380
Pubmed

Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance.

ATOH7 RAX OTX2 VSX2

1.09e-071699431949107
Pubmed

Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation.

ATOH7 RAX OTX1 OTX2 VSX2

1.32e-074299530485816
Pubmed

Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development.

LEFTY2 LEFTY1 OTX2 FURIN

1.83e-071899417936261
Pubmed

Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl.

DUX4L9 DUX4L2 DUX4L4

2.23e-07599320063414
Pubmed

Mutational screening of CHX10, GDF6, OTX2, RAX and SOX2 genes in 50 unrelated microphthalmia-anophthalmia-coloboma (MAC) spectrum cases.

RAX OTX2 VSX2

2.23e-07599320494911
Pubmed

Minimization of exogenous signals in ES cell culture induces rostral hypothalamic differentiation.

RAX CRX OTX2 VSX2

2.32e-071999418697938
Pubmed

Proper patterning of the optic fissure requires the sequential activity of BMP7 and SHH.

ATOH7 RAX OTX2 VSX2

2.89e-072099416854970
Pubmed

Temporal requirement of the protein tyrosine phosphatase Shp2 in establishing the neuronal fate in early retinal development.

ATOH7 CRX OTX2 VSX2

3.56e-072199420237281
Pubmed

Extraembryonic proteases regulate Nodal signalling during gastrulation.

LEFTY2 LEFTY1 OTX2 FURIN

3.56e-072199412447384
Pubmed

Smad4 is required predominantly in the developmental processes dependent on the BMP branch of the TGF-β signaling system in the embryonic mouse retina.

ATOH7 RAX CRX VSX2

3.56e-072199421273545
Pubmed

Sall4 isoforms act during proximal-distal and anterior-posterior axis formation in the mouse embryo.

LEFTY2 LEFTY1 OTX2 FURIN

3.56e-072199418781635
Pubmed

Zac1 functions through TGFbetaII to negatively regulate cell number in the developing retina.

ATOH7 RAX CRX VSX2

3.56e-072199417559664
Pubmed

The atypical homeoprotein Pbx1a participates in the axonal pathfinding of mesencephalic dopaminergic neurons.

MEIS3 MEIS1 MEIS2 PKNOX1

4.34e-072299422748019
Pubmed

Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping.

LEFTY2 LEFTY1 FURIN

4.45e-07699310603343
Pubmed

MEIS proteins as partners of the TLX1/HOX11 oncoprotein.

MEIS1 MEIS2 PKNOX1

4.45e-07699319559479
Pubmed

Characterization of TALE genes expression during the first lineage segregation in mammalian embryos.

MEIS3 MEIS1 PKNOX1

4.45e-07699322987645
Pubmed

Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome.

MEIS3 MEIS1 MEIS2 PKNOX1

5.25e-072399418691704
Pubmed

Disruption of early proximodistal patterning and AVE formation in Apc mutants.

LEFTY2 LEFTY1 OTX2 MIXL1

5.25e-072399416887818
Pubmed

A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development.

RAX CRX OTX2 VSX2

5.25e-072399422792072
Pubmed

Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity.

MEIS1 MEIS2 PKNOX1

7.77e-07799320413611
Pubmed

PBX, MEIS, and IGF-I are potential mediators of retinoic acid-induced proximodistal limb reduction defects.

MEIS3 MEIS1 MEIS2

7.77e-07799312397630
Pubmed

The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection.

DUX4L9 DUX4L2 DUX4L4

7.77e-07799330765463
Pubmed

The T-box transcription factor Eomesodermin is essential for AVE induction in the mouse embryo.

LEFTY2 LEFTY1 OTX2 MIXL1

8.80e-072699423651855
Pubmed

Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina.

ATOH7 CRX OTX2 VSX2

8.80e-072699419828801
Pubmed

Forkhead box N4 (Foxn4) activates Dll4-Notch signaling to suppress photoreceptor cell fates of early retinal progenitors.

ATOH7 CRX OTX2 VSX2

1.03e-062799422323600
Pubmed

Requirement for Pbx1 in skeletal patterning and programming chondrocyte proliferation and differentiation.

MEIS3 MEIS1 MEIS2 PKNOX1

1.03e-062799411566859
Pubmed

LHX2 is necessary for the maintenance of optic identity and for the progression of optic morphogenesis.

RAX CRX OTX2 VSX2

1.20e-062899423595746
Pubmed

Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast.

MEIS2 LEFTY2 LEFTY1 OTX2

1.20e-062899411412024
Pubmed

TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling.

LEFTY2 LEFTY1 OTX2 MIXL1

1.20e-062899427760115
Pubmed

Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning.

LEFTY2 LEFTY1 OTX2 FURIN

1.20e-062899416728477
Pubmed

Secreted frizzled-related proteins are required for Wnt/β-catenin signalling activation in the vertebrate optic cup.

CRX OTX1 OTX2 VSX2

1.20e-062899421896628
Pubmed

Notch pathway mutants do not equivalently perturb mouse embryonic retinal development.

ATOH7 CRX OTX2 VSX2

1.20e-062899437751417
Pubmed

Dual requirement for Pax6 in retinal progenitor cells.

ATOH7 CRX OTX2

1.24e-06899319004853
Pubmed

Patterning the optic neuroepithelium by FGF signaling and Ras activation.

ATOH7 RAX VSX2

1.24e-06899311748141
Pubmed

Canonical Wnt/β-catenin signalling is essential for optic cup formation.

RAX CRX OTX2 VSX2

1.39e-062999424324671
Pubmed

Distinct effects of Hedgehog signaling on neuronal fate specification and cell cycle progression in the embryonic mouse retina.

ATOH7 RAX CRX OTX2

1.39e-062999419474320
Pubmed

Requirements for Neurogenin2 during mouse postnatal retinal neurogenesis.

ATOH7 CRX OTX2 VSX2

1.39e-062999430048641
Pubmed

Lhx2 links the intrinsic and extrinsic factors that control optic cup formation.

RAX OTX1 OTX2 VSX2

1.39e-062999419906857
Pubmed

Sma- and Mad-related protein 7 (Smad7) is required for embryonic eye development in the mouse.

ATOH7 RAX OTX2 VSX2

1.60e-063099423426374
Pubmed

Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10.

ATOH7 OTX1 OTX2 VSX2

1.60e-063099415459106
Pubmed

Phase transition specified by a binary code patterns the vertebrate eye cup.

ATOH7 OTX1 OTX2 VSX2

1.83e-063199434757798
Pubmed

Signaling and transcriptional regulation in early mammalian eye development: a link between FGF and MITF.

CRX OTX2 VSX2

1.86e-06999310903182
Pubmed

Differential expression of retinoic acid-inducible (Stra) genes during mouse placentation.

MEIS2 LEFTY2 LEFTY1

1.86e-06999310727869
Pubmed

Genetic dissection of nodal function in patterning the mouse embryo.

LEFTY2 LEFTY1 OTX2

1.86e-06999311311163
Pubmed

Genetic chimeras reveal the autonomy requirements for Vsx2 in embryonic retinal progenitor cells.

OTX1 OTX2 VSX2

1.86e-06999325927996
Pubmed

No turning, a mouse mutation causing left-right and axial patterning defects.

LEFTY2 LEFTY1 OTX2

2.65e-06109939466889
Pubmed

Disrupting Foxh1-Groucho interaction reveals robustness of nodal-based embryonic patterning.

LEFTY2 LEFTY1 OTX2

2.65e-061099325511461
Pubmed

Mutational screening of 10 genes in Chinese patients with microphthalmia and/or coloboma.

RAX OTX2 VSX2

2.65e-061099320057906
Pubmed

Visceral endoderm mediates forebrain development by suppressing posteriorizing signals.

LEFTY2 LEFTY1 OTX2

2.65e-061099310985852
Pubmed

Identification of a new family of Pbx-related homeobox genes.

MEIS3 MEIS1 MEIS2

2.65e-06109938950991
Pubmed

Efficient cloning of cDNAs of retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (mouse LERK-2/Eplg2).

MEIS2 LEFTY2 LEFTY1

2.65e-06109937649373
Pubmed

Superactivation of Pax6-mediated transactivation from paired domain-binding sites by dna-independent recruitment of different homeodomain proteins.

RAX PKNOX1 VSX2

2.65e-061099311069920
Pubmed

The Retinal Pigment Epithelium Is a Notch Signaling Niche in the Mouse Retina.

ATOH7 CRX OTX2 VSX2

3.02e-063599428402857
Pubmed

Mouse Lefty2 and zebrafish antivin are feedback inhibitors of nodal signaling during vertebrate gastrulation.

LEFTY2 LEFTY1 OTX2

3.63e-061199310518210
Pubmed

Natural antisense transcripts associated with genes involved in eye development.

RAX CRX OTX2

3.63e-061199315703187
Pubmed

Expression patterns of vHNF1 and HNF1 homeoproteins in early postimplantation embryos suggest distinct and sequential developmental roles.

LEFTY2 LEFTY1 OTX2

3.63e-06119931363228
Pubmed

PRDM15 loss of function links NOTCH and WNT/PCP signaling to patterning defects in holoprosencephaly.

LEFTY2 LEFTY1 OTX2

3.63e-061199331950080
Pubmed

G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells.

RAX CRX OTX2 VSX2

3.80e-063799423223288
Pubmed

Vsx2 controls eye organogenesis and retinal progenitor identity via homeodomain and non-homeodomain residues required for high affinity DNA binding.

OTX1 OTX2 VSX2

4.83e-061299323028343
Pubmed

The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis.

LEFTY2 LEFTY1 OTX2

4.83e-06129939671576
Pubmed

AVE protein expression and visceral endoderm cell behavior during anterior-posterior axis formation in mouse embryos: Asymmetry in OTX2 and DKK1 expression.

LEFTY2 LEFTY1 OTX2

4.83e-061299325910836
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

RNF31 MEIS3 RAX MEIS1 MEIS2 PKNOX2 OTX1 OTX2 PKNOX1 ZFHX3 VSX2

5.80e-06709991122988430
Pubmed

Cripto promotes A-P axis specification independently of its stimulatory effect on Nodal autoinduction.

LEFTY2 LEFTY1 OTX2

6.27e-061399318268105
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

KDM5C MEIS3 CXXC1 RAX MEIS1 MEIS2 PKNOX2 OTX2 MIXL1 PKNOX1 TGIF2LX VSX2

7.60e-06877991220211142
InteractionRAX2 interactions

RAX2 CRX

1.89e-052882int:RAX2
InteractionPBX1 interactions

MEIS1 MEIS2 CRX PKNOX2 PKNOX1

3.53e-0585885int:PBX1
InteractionPBX4 interactions

MEIS3 MEIS1 MEIS2 PKNOX2 PKNOX1

3.73e-0586885int:PBX4
InteractionCARTPT interactions

RNF31 KDM5C MEIS1 MEIS2

4.41e-0545884int:CARTPT
InteractionM1AP interactions

CRX OTX1 OTX2

5.23e-0517883int:M1AP
InteractionPBX2 interactions

MEIS1 MEIS2 CRX PKNOX2 PKNOX1

6.65e-0597885int:PBX2
Cytoband4q35.2

DUX4L2 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

2.04e-11279664q35.2
CytobandEnsembl 112 genes in cytogenetic band chr4q35

DUX4L9 DUX4L2 DUX4 DUX4L5 DUX4L6 DUX4L3 DUX4L4 DUX4L7

1.54e-10117968chr4q35
Cytoband1q42.1

LEFTY2 LEFTY1

2.82e-04129621q42.1
CytobandEnsembl 112 genes in cytogenetic band chr16q22

ZNF821 PKD1L3 FCSK ZFHX3

6.10e-04183964chr16q22
Cytoband9q34.13

NIBAN2 CFAP77

8.85e-04219629q34.13
Cytoband16q22.2

ZNF821 PKD1L3

9.73e-042296216q22.2
Cytoband2p13

OTX1 ALMS1

1.06e-03239622p13
Cytoband2p14

MEIS1 DNAAF10

1.93e-03319622p14
GeneFamilyPRD class homeoboxes and pseudogenes

DUXA DUX4L9 ISX DUX4L2 RAX2 RAX CRX OTX1 OTX2 MIXL1 DUX4L5 VSX2 DUX4L6 DUX4L3 DUX4L4 DUX4L7

1.31e-22927116521
GeneFamilyTALE class homeoboxes and pseudogenes

MEIS3 MEIS1 MEIS2 MEIS3P1 PKNOX2 PKNOX1 TGIF2LX

6.59e-1226717526
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

MXRA5 SYNE1 MEIS3 MEIS1 IGSF10 MYOF MGP PZP

6.68e-09197908fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MXRA5 SYNE1 MEIS3 MEIS1 PKNOX2 IGSF10 MYOF PZP

7.23e-091999088b86c69aaf60feff53aa782559cfece7342a23de
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MEIS3 MEIS1 MEIS2 PKNOX2 IGSF10 MYOF MGP

7.07e-081769079bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MEIS3 MEIS1 MEIS2 PKNOX2 IGSF10 MYOF MGP

7.07e-081769073f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYNE1 MEIS1 PKNOX2 IGSF10 MYOF MGP PZP

1.37e-071949076e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEIS3 MEIS2 LEFTY2 FREM2 MYOF MGP PLAT

1.42e-071959078a04f0e92d10a368ccda5f566ae67ef51f1d34a9
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

MXRA5 SYNE1 MEIS1 IGSF10 MYOF MGP PZP

1.63e-07199907e1849505b92820a219c5a2c35492bdd55579fb48
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SYNE1 ADCY5 MYOF MGP PLAT ZFHX3 PZP

1.69e-07200907b22cae282591d8dead9869c2adbb9632615f50f7
ToppCellCOVID-19-kidney-vSMC/Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADCY5 MEIS1 MEIS2 TBC1D1 ZFHX3 MYOM2

1.72e-06179906111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MEIS3 ADCY5 MEIS1 PKNOX2 ZFHX3 PEAR1

2.22e-0618790686250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 ADCY5 PKNOX2 MYOF AGRN DCBLD2

2.29e-06188906b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 ADCY5 PKNOX2 MYOF AGRN DCBLD2

2.29e-06188906874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 MEIS1 MEIS2 TBC1D1 ZFHX3 MYOM2

2.36e-061899067fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 MEIS1 MEIS2 TBC1D1 ZFHX3 MYOM2

2.36e-0618990606b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYNE1 ADCY5 MEIS1 MYOF ZFHX3 PZP

2.36e-061899067ab1cfc1657277858339f7258a0c4ae9cb42fdf8
ToppCellLPS_only-Stromal_mesenchymal-Lung_smooth_muscle|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYNE1 ADCY5 MEIS1 MYOF ZFHX3 PZP

2.51e-0619190608042952431ca1a6fd7dfc13f36eb28643979598
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MXRA5 MEIS3 MEIS2 MYOF MGP PLAT

2.51e-06191906156b467187331ac6ca390d6ca861d9670bb7b956
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 MEIS1 MEIS2 PKNOX2 MGP ZFHX3

2.51e-0619190604c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 MEIS1 MEIS2 TBC1D1 ZFHX3 MYOM2

2.58e-06192906bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 MEIS1 MEIS2 TBC1D1 ZFHX3 MYOM2

2.58e-06192906b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEIS3 MEIS2 ZNF106 MYOF MGP PLAT

2.82e-06195906bd7526dd80a60ff7bc866e4f5a0e8acdbc10d191
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP1 MEIS3 MEIS1 MEIS2 PKNOX2 MGP

2.82e-0619590649c99553629cdd83ee56a2e508d5bc8d34b8507b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

BRINP1 MEIS3 MEIS1 MEIS2 PKNOX2 MGP

2.82e-06195906dd281a249854800f737dc22e0f375f66dfb5cf5f
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

ALLC MXRA5 MGP PLAT AGRN PEAR1

2.99e-06197906af819b0561c8db582c5b466d804153d69d3297e0
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TERT ADCY5 MEIS1 MGP MYOM2 PZP

3.08e-06198906d1827e3707b929e3a3562989a0c11537d344e164
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MXRA5 MEIS3 IGSF10 MYOF MGP PZP

3.17e-06199906ba586690f88fd051f449753bfe7603a2cb431782
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MXRA5 MEIS3 IGSF10 MYOF MGP PZP

3.17e-0619990606a7d874ff7c4616577f6e59d3118717a8c47c00
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SYNE1 MEIS1 IGSF10 MYOF MGP PZP

3.17e-06199906a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SYNE1 MEIS1 IGSF10 MYOF MGP PZP

3.17e-0619990630d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE1 ADCY5 MYOF MGP ZFHX3 PZP

3.27e-062009069169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ADCY5 PKNOX2 MYOF PLAT ZFHX3 PZP

3.27e-062009064e1e19214aeebbdca004de7faaf4cc9d18498591
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SYNE1 MEIS1 IGSF10 MYOF MGP PZP

3.27e-0620090644a68bacdb3d5bf563bd35952176995850933a81
ToppCellLPS_anti-TNF-Mesenchymal_myocytic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE1 ADCY5 MYOF PLAT ZFHX3 PZP

3.27e-0620090667dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte|LPS_only / Treatment groups by lineage, cell group, cell type

SYNE1 ADCY5 MYOF MGP PLAT ZFHX3

3.27e-062009068c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCellLPS_IL1RA_TNF-Mesenchymal_fibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SYNE1 MEIS1 IGSF10 MYOF MGP PZP

3.27e-06200906dc61016c61729f69649cfb21f6264e685ce83dea
ToppCellLPS_only-Mesenchymal_myocytic|LPS_only / Treatment groups by lineage, cell group, cell type

SYNE1 ADCY5 MYOF MGP ZFHX3 PZP

3.27e-062009068bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCellLPS_IL1RA-Mesenchymal_myocytic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SYNE1 ADCY5 MYOF MGP ZFHX3 PZP

3.27e-0620090677631c471cc5d453a749784f838cfa6408caf09b
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

MEIS3 ADCY5 MEIS1 PKNOX2 TBC1D1

2.13e-051659058a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEIS3 MEIS2 LEFTY2 MGP PLAT

2.33e-0516890574d6dbf9295933acdee785af9b73a94377d15412
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MXRA5 GRIA3 MYOF CRYBG3 ADAMTS14

2.39e-05169905c0824a93674e2bff0f09b2d2fab5bab016a2e379
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MEIS1 MEIS2 TBC1D1 ZFHX3 MYOM2

2.46e-0517090599dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MEIS1 MEIS2 TBC1D1 ZFHX3 MYOM2

2.46e-051709053a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MEIS1 MEIS2 TBC1D1 ZFHX3 MYOM2

2.46e-05170905cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCellCOVID-19-kidney-PEC|kidney / Disease (COVID-19 only), tissue and cell type

SYNE1 ADCY5 MEIS2 PKNOX2 DCBLD2

2.60e-0517290536a96714a0eb6ac438648135336c9791881ddadb
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNE1 MEIS2 MYOF MGP PLAT

3.07e-051789050fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCellCOVID-19-kidney-Epi_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

SYNE1 MEIS1 MEIS2 PKNOX2 DCBLD2

3.15e-05179905e7c9dc63f03d3f3746b51a7e3c8393089e2ceb7d
ToppCelldroplet-Liver-LIVER_HEP-30m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIS2 ADD3 IGSF10 PLAT PEAR1

3.24e-05180905dd1b10c7f5a0fbc63163844ca1882884a24a84d3
ToppCelldroplet-Liver-LIVER_HEP|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIS2 ADD3 IGSF10 PLAT PEAR1

3.24e-05180905423454e3390080ae03bb3cbb267255ebfe4df080
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MEIS2 MYOF TBC1D1 ZFHX3 CRYBG3

3.24e-05180905e8841ef1239f9ee73ac4f4e11faca0742694f368
ToppCellE18.5-samps-Mesenchymal-Matrix_fibroblast|E18.5-samps / Age Group, Lineage, Cell class and subclass

GRIA3 BRINP1 MEIS1 MGP TSLP

3.41e-05182905ceb37c214662a48efb56ab0d015977c6fab478b0
ToppCell3'_v3-blood-Hematopoietic_Erythro-Mega|blood / Manually curated celltypes from each tissue

MEIS1 IGSF10 BEX3 LEFTY1 PEAR1

3.41e-051829053100165c5ba8c3016f9a2f7a8e4ea136750823fe
ToppCell10x5'v1-week_17-19-Hematopoietic-MK-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MEIS1 IGSF10 BEX3 MIXL1 PEAR1

3.50e-051839059c66a40c355387f805dbdca4162dd05af5c1d8d4
ToppCelldroplet-Liver-Hepatocytes-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIS1 MEIS2 ADD3 LEFTY1 TBC1D1

3.69e-05185905efcfbf5a48b3ea9a425183e5c2eec6a9585415a0
ToppCelldroplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIS1 MEIS2 ADD3 LEFTY1 TBC1D1

3.69e-05185905642088ace9230d38b0579853c54ff4dd8b5d5df4
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

MEIS1 PKNOX2 MGP GPR153 ZFHX3

3.69e-051859059f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

MEIS1 PKNOX2 MGP GPR153 ZFHX3

3.69e-051859051ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

MEIS1 PKNOX2 MGP GPR153 ZFHX3

3.88e-0518790513731298bc562ec29582f5da1b4c97261284f6f1
ToppCell10x5'v1-week_17-19-Hematopoietic-MK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MEIS1 IGSF10 BEX3 MIXL1 PEAR1

3.88e-0518790534cad5ac8602fe88ca3d421257190c9a388d4cb0
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Neuronal-Neuron|GW09 / Sample Type, Dataset, Time_group, and Cell type.

ZNF821 MEIS3 GRAMD1B MGP MYOM2

4.08e-051899053717d1148e26ac78a26aea0ca1dbfbb9d3668877
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TBC1D1 PLAT ZFHX3 TSLP PEAR1

4.19e-0519090510b02c62e72bfea9767e3e751011436925da823e
ToppCellCOVID-19-kidney-vSMC/Pericyte|kidney / Disease (COVID-19 only), tissue and cell type

MEIS1 MEIS2 MGP ZFHX3 MYOM2

4.29e-05191905fad8eaa536001b911d05ae2b12150c2398cc6f88
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

MEIS1 MEIS2 BEX3 ZFHX3 RPL3

4.29e-05191905509d17d8ee0d028757ce0f2c9b97e5875f06f0ab
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SYNE1 ADCY5 MYOF ZFHX3 PZP

4.29e-051919057853ac7dff649150e6ff27cd4c8cf7c1fc034ed4
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MEIS1 PKNOX2 MYOF MGP PZP

4.40e-05192905162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LEFTY2 MGP TBC1D1 ZFHX3 MYOM2

4.40e-05192905dee97f650ae6f4d07a142ade402aae1905791a22
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MEIS1 IGSF10 MYOF MGP PZP

4.40e-051929053d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MEIS1 PKNOX2 MYOF MGP PZP

4.40e-051929054e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MEIS1 PKNOX2 MYOF MGP PZP

4.40e-05192905ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIS1 MEIS2 IGSF10 MGP GPR153

4.51e-05193905ebd090d7801480b3cee45caac3d30cc991836769
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEIS2 LEFTY2 FREM2 MYOF MGP

4.51e-051939050256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MEIS1 MEIS2 IGSF10 MGP GPR153

4.51e-05193905573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 MEIS1 MEIS2 TBC1D1 ZFHX3

4.62e-051949055c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MEIS1 PKNOX2 IGSF10 MYOF PZP

4.62e-0519490589b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell5'-GW_trimst-2-SmallIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEIS3 MEIS2 FREM2 MYOF MGP

4.62e-05194905d2bafd31bb8333f66b6c714944bceb2f1aa11740
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 MEIS1 MEIS2 TBC1D1 ZFHX3

4.62e-05194905ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 MEIS1 MEIS2 MGP ZFHX3

4.62e-05194905ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellE12.5-Mesenchymal-mesenchymal_fibroblast|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MEIS1 MEIS2 MGP PLAT RPL3

4.74e-05195905def0a3fb36eec6fbb08e1323baf2b22b28bf751a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADCY5 MEIS1 MEIS2 MGP ZFHX3

4.85e-05196905b8759e6231e0254797d6c30930407b79440c57bb
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MXRA5 MGP PLAT AGRN PEAR1

4.97e-0519790512370ee857fddf1cf26196b23c21b68dcea48eb3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 MEIS1 MEIS2 MYOF MGP

4.97e-051979059b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEIS3 MEIS1 MEIS2 MGP PLAT

5.09e-05198905cfe2d52b19a1b4c2c2076fa1d5a69baf21a49623
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE1 MEIS1 MYOF MGP PZP

5.22e-05199905e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MEIS1 PKNOX2 MYOF MGP PZP

5.22e-05199905fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

MEIS1 PKNOX2 MYOF MGP PZP

5.22e-05199905211c3a08f2d484ab7a3368006767289088f0d957
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

MEIS1 PKNOX2 MYOF MGP PZP

5.22e-051999051a0add79f4e34078b3475eb11c85a4234bda197c
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_1_(HAND1+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MEIS3 MEIS1 MEIS2 BEX3 PLAT

5.22e-051999054217b9e66c5374461e84bdb893ab650f148286c8
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE1 IGSF10 MYOF MGP PZP

5.34e-052009059b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

MEIS1 BEX3 MYOF MGP PZP

5.34e-05200905ab4fda0cc95cb8f80ea9f28745013f3248def820
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE1 IGSF10 MYOF MGP PZP

5.34e-05200905b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE1 IGSF10 MYOF MGP PZP

5.34e-0520090550ca6550998e461ef26dd670351060bd940765a8
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SYNE1 ADCY5 MYOF ZFHX3 PZP

5.34e-05200905f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

SYNE1 ADCY5 MYOF MGP ZFHX3

5.34e-05200905a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCellControl_saline-Mesenchymal_myocytic|Control_saline / Treatment groups by lineage, cell group, cell type

SYNE1 MEIS3 ADCY5 MYOF PZP

5.34e-052009055ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Diff_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE1 IGSF10 MYOF MGP PZP

5.34e-052009053bdba9612cd7c612b76aa9abecc4a6529aabfc1c
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE1 MEIS1 MYOF MGP PZP

5.34e-05200905c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ADCY5 PKNOX2 MYOF PLAT ZFHX3

5.34e-05200905786f1ae53e60b5ffbf4bfd393d10b802478148b3
ToppCellControl_saline-Mesenchymal_myocytic-Pericyte|Control_saline / Treatment groups by lineage, cell group, cell type

ADCY5 PKNOX2 MGP ZFHX3 PZP

5.34e-05200905cb7ef774b6d300f8019c5b16a04e3ebd165e4f1c
ToppCellLPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_2|LPS_only / Treatment groups by lineage, cell group, cell type

MEIS3 ADCY5 MYOF PLAT ZFHX3

5.34e-0520090569edc375d85689300d1dbc1217fedc40063ecdcb
ToppCelldistal-3-mesenchymal-Alveolar_Fibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LEFTY2 IGSF10 LEFTY1 MGP PLAT

5.34e-0520090520112be28f80baffad92641c9cfd7c3718967dbb
ToppCellStriatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Drd1-Excitatory_Neuron.Gad1Gad2.Drd1-Fos_(dSPN,_IEG+)-|Striatum / BrainAtlas - Mouse McCarroll V32

ALLC MROH6 VSX2

1.03e-0445903cce61a18a2d2ac9c3113ef7d9fe8adf70bad773c
Diseaserestless legs syndrome (implicated_via_orthology)

MEIS3 MEIS1 MEIS2 MEIS3P1 PKNOX2

1.04e-118865DOID:0050425 (implicated_via_orthology)
Diseaseleukemia (implicated_via_orthology)

MEIS3 MEIS1 MEIS2 MEIS3P1 PKNOX2

2.10e-0919865DOID:1240 (implicated_via_orthology)
DiseaseDisorder of eye

RAX2 KIF7 CRX FREM2 OTX2 ALMS1 MFN2 VSX2

2.04e-07212868C0015397
DiseaseMICROPHTHALMIA, ISOLATED 1

RAX OTX2 VSX2

8.30e-077863C1855052
DiseaseMicrophthalmos, Autosomal Recessive

RAX OTX2 VSX2

8.30e-077863C4551977
DiseaseAnophthalmia-microphthalmia syndrome

RAX OTX2 VSX2

3.06e-0521863cv:C5680330
DiseaseDevelopmental delay (disorder)

SZT2 KDM5C GLRA1

1.73e-0437863C0424605
DiseasePARTINGTON X-LINKED MENTAL RETARDATION SYNDROME

KDM5C GRIA3

2.32e-048862C0796250
DiseaseAnti-Toxoplasma gondii IgG measurement

GRAMD1B DCBLD2

2.98e-049862EFO_0009353
DiseaseN-delta-acetylornithine measurement

ALMS1 FBXO41

5.44e-0412862EFO_0800067
DiseaseGlobal developmental delay

SZT2 KDM5C FCSK GLRA1

6.29e-04133864C0557874
DiseaseAnimal Mammary Neoplasms

ADCY5 MGP FURIN RPL3

8.04e-04142864C0024667
DiseaseMammary Carcinoma, Animal

ADCY5 MGP FURIN RPL3

8.04e-04142864C1257925
Diseasephotoreceptor cell layer thickness measurement

ATOH7 RAX2 RAX VSX2

9.38e-04148864EFO_0803370
DiseaseMammary Neoplasms, Experimental

ADCY5 MGP FURIN RPL3

1.11e-03155864C0024668
Diseasetransient cerebral ischemia (biomarker_via_orthology)

ITGAM BEX3 MFN2 PLAT

1.17e-03157864DOID:224 (biomarker_via_orthology)
DiseaseCarcinomatosis

ADCY5 MGP FURIN RPL3

1.34e-03163864C0205699
DiseaseCarcinoma, Spindle-Cell

ADCY5 MGP FURIN RPL3

1.34e-03163864C0205697
DiseaseUndifferentiated carcinoma

ADCY5 MGP FURIN RPL3

1.34e-03163864C0205698
DiseaseAnaplastic carcinoma

ADCY5 MGP FURIN RPL3

1.34e-03163864C0205696
DiseaseCarcinoma

ADCY5 MGP FURIN RPL3

1.37e-03164864C0007097
DiseaseRetinal Degeneration

RAX2 CRX

1.70e-0321862C0035304
Diseasehaptoglobin measurement

PKD1L3 ZFHX3

1.70e-0321862EFO_0004640
Diseasenose morphology measurement, mouth morphology measurement

MEIS3 MEIS3P1

1.70e-0321862EFO_0007843, EFO_0007955

Protein segments in the cluster

PeptideGeneStartEntry
LTRWRKQQQPVRRTV

CFAP77

11

Q6ZQR2
DWILQNRRHPQRNFI

CRYBG3

2361

Q68DQ2
HQLPRERTIQQWLAR

BRINP1

376

O60477
RRLAPNFRWAIPNRQ

BEX3

41

Q00994
NSQQRWTHIRLNIFP

ALLC

156

Q8N6M5
RQQREKTRWLNSPNT

ADD3

431

Q9UEY8
PRVQIWFQNERSRQL

DUX4L4

61

P0CJ87
WRQQAECRQQRAIPS

AGRN

441

O00468
LWNKYRERQRQQRQP

ALMS1

3601

Q8TCU4
PRVQIWFQNERSRQL

DUX4L6

61

P0CJ89
IQARTPAQWRENSQL

BOLA1

106

Q9Y3E2
VTPQQQQRLASRWRS

ADCY5

61

O95622
QILWFRGLNRIQTQI

ATP2B3

1101

Q16720
RLQERLPQSQTEWAQ

GRAMD1B

666

Q3KR37
WQEDFRELFRQPLRQ

ADAMTS14

136

Q8WXS8
LPEARVQIWFQNQRA

ISX

121

Q2M1V0
LPEVRVQVWFQNRRA

RAX2

66

Q96IS3
LENPRRNRIAQWQSL

PZP

166

P20742
PVWAARRRLAQNALN

CYP1A2

131

P05177
PQERQRQWIQISDAV

NIBAN2

261

Q96TA1
ILQVNNWFINARRRI

MEIS1

316

O00470
DSVQQRVRQWLRPQE

CAPN15

506

O75808
RVRQWLRPQEINCSV

CAPN15

511

O75808
TEAVNFWQQLSRPRQ

LEFTY1

181

O75610
PRVQIWFQNERSRQL

DUX4

61

Q9UBX2
LQVNNWFINARRRIV

MEIS2

321

O14770
PESRIQIWFQNRRAR

DUX5

161

Q96PT3
VQFNPGQTRATWRVR

FREM2

1826

Q5SZK8
TVWQVRHLPQNRELF

DNAAF10

261

Q96MX6
PRVQIWFQNERSRQL

DUX4L3

61

P0CJ86
ENPMVQQFIQRWVRL

GRIA3

276

P42263
FWDSQRRRQPQPQRD

PEAR1

961

Q5VY43
VVQLRRQRPDFEWNE

GPR153

66

Q6NV75
AQNIRNRATVNWRPE

KIF7

346

Q2M1P5
QWRRQPTRLFVVVLA

MRGPRD

211

Q8TDS7
ILQVNNWFINARRRI

MEIS3

306

Q99687
LWRSLSRNQRVNGQV

MROH6

206

A6NGR9
NLTPRQRFRVAVWTV

PHKG2

301

P15735
ERLSRPNIFILNNRW

MFN2

246

O95140
NLPESRVQVWFKNRR

OTX1

76

P32242
QSARAQLWRELRDQP

FCSK

301

Q8N0W3
ANRIYEILPQRIQQW

CXXC1

401

Q9P0U4
TRFSRRKIPWQQNFV

IGSF10

1196

Q6WRI0
WFQNNRARLPPEERQ

CPHXL2

71

A0A1W2PPK0
RLQREPQVQWLEQQV

FURIN

86

P09958
PRVQIWFQNERSRQL

DUX4L9

61

Q6RFH8
LNTAFDRLRRVVPQW

ATOH7

56

Q8N100
RNPQELWRFLTQNLS

ABCA2

156

Q9BZC7
PESRIQLWFQNRRAR

DUX3

161

Q96PT4
PRVQIWFQNERSRQL

DUX4L7

61

P0CJ90
TEAVNFWQQLSRPRQ

LEFTY2

181

O00292
GLRRQAIQNWQRRPR

FBXO41

461

Q8TF61
PRVQIWFQNERSCQL

DUX1

61

O43812
PRSRWQVLTALRQRQ

DCAF8L1

151

A6NGE4
ARFIRVNPTQWQQKI

DCBLD2

426

Q96PD2
PNWRKLRLITFNRNE

CLDN12

31

P56749
ENILNPLRRWNETFQ

SDR39U1

61

Q9NRG7
PRVQIWFQNERSRQL

DUX4L5

61

P0CJ88
RRFRQPQWQLLDPNA

SLC22A11

86

Q9NSA0
PESRVQIWFQNRRSR

DUXA

141

A6NLW8
NRRNANTFISPQQRW

MGP

36

P08493
TLLQVNNWFINARRR

PKNOX2

331

Q96KN3
INLPESRVQVWFKNR

CRX

76

O43186
LTRNQAQQPFSLWAR

OSGIN1

226

Q9UJX0
NLPESRVQVWFKNRR

OTX2

76

P32243
LQVNNWFINARRRIV

MEIS3P1

206

A6NDR6
LGRNFLQWRRPTQQA

SZT2

2611

Q5T011
EELQQNRRWNSREVP

SPATA48

161

A4D263
QISNWFINARRRILP

TGIF2LX

96

Q8IUE1
AQQRRGIIDSQIRQW

SYNE1

7551

Q8NF91
VNNWFINARRRILQP

PKNOX1

306

P55347
WARERLEQQVPVNQV

RPL3

196

P39023
YRVNIFLRQQWNDPR

GLRA1

86

P23415
IATRHPWNQFTRVQR

PKD1L3

891

Q7Z443
RLNQTVIWDRPQVTF

ITGAM

976

P11215
QQQQRTREWVARHPQ

SOWAHB

301

A6NEL2
PEVRVQVWFQNRRAK

RAX

176

Q9Y2V3
PWDQAVQRRSRLQRR

SSH3

21

Q8TE77
RTVRIWRQYLPGNEQ

CIAO1

216

O76071
QQVRRRWESFVAIFP

C11orf86

91

A6NJI1
ELQRQRLEPFRQRLW

RNF31

611

Q96EP0
WLFIREQRTQQQRSG

STYK1

46

Q6J9G0
QQHQSWLRPVLRSNR

PLAT

51

P00750
VRTNQIPRQIPEQRW

TM9SF4

481

Q92544
PESRIQVWFQNRRAK

MIXL1

126

Q9H2W2
WRQQIFLRVATPQKA

TBC1D1

661

Q86TI0
SVNPNRRLTSQQWRL

TEX10

211

Q9NXF1
VSQLQGLWRRFNRPL

TSLP

141

Q969D9
WREGRVFLQDQNPNR

ZNF705G

66

A8MUZ8
QTPSVRKWALRRQNE

ZNF821

251

O75541
NQEINSDDRRPQWRR

ZNF106

91

Q9H2Y7
RRLVQLLRQHSSPWQ

TERT

446

O14746
LPTRVIVVWFQNARQ

ZFHX3

2281

Q15911
FQVITINPRNSRWAE

VN1R2

186

Q8NFZ6
ELPEDRIQVWFQNRR

VSX2

186

P58304
PRVQIWFQNERSRQL

DUX4L2

61

P0CJ85
PEAQQLQRQVEQARW

KDM5C

916

P41229
WVMQPSIDIQLNRRQ

MXRA5

431

Q9NR99
TWRDQLRPTQLLQNV

MYOF

1666

Q9NZM1
WQRVNAQTAVRSPRY

MYOM2

556

P54296
RPSFNRVAQGWVRNL

MYOZ3

231

Q8TDC0