Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ubiquitin protein ligase activity	TRAF3 TRIM4 DTX1 UBR4 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3	9.92e-10	372	74	13	GO:0061630
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	TRAF3 BRCA1 TRIM4 DTX1 UBR4 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3	1.80e-09	473	74	14	GO:0004842
GeneOntologyMolecularFunction	ubiquitin-like protein ligase activity	TRAF3 TRIM4 DTX1 UBR4 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3	2.25e-09	398	74	13	GO:0061659
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	TRAF3 BRCA1 TRIM4 DTX1 UBR4 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3	4.96e-09	512	74	14	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	TRAF3 BRCA1 TRIM4 DTX1 UBR4 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3	8.06e-09	532	74	14	GO:0016755
GeneOntologyMolecularFunction	acyltransferase activity	TRAF3 BRCA1 TRIM4 DTX1 UBR4 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3	8.21e-07	775	74	14	GO:0016746
GeneOntologyMolecularFunction	extracellular matrix structural constituent	THBS1 SPARC FBN2 SPON1 LTBP1 MUC5AC FBN3	6.20e-06	188	74	7	GO:0005201
GeneOntologyMolecularFunction	zinc ion binding	MORC1 TRAF3 BRCA1 TRIM4 DTX1 UBR4 MIB1 TRIM55 TRIM54 TRIM68 KDM1B AGBL2 TRIM3	2.13e-05	891	74	13	GO:0008270
GeneOntologyMolecularFunction	transition metal ion binding	MORC1 TRAF3 B4GALT7 BRCA1 TRIM4 DTX1 UBR4 XPNPEP3 MIB1 TRIM55 TRIM54 TRIM68 KDM1B AGBL2 TRIM3	2.53e-05	1189	74	15	GO:0046914
GeneOntologyMolecularFunction	structural molecule activity	POTEE THBS1 SPARC FBN2 DST POTEF SPON1 KRT40 LTBP1 MUC5AC FBN3	4.19e-04	891	74	11	GO:0005198
GeneOntologyMolecularFunction	structural constituent of postsynaptic actin cytoskeleton	POTEE POTEF	7.29e-04	11	74	2	GO:0098973
GeneOntologyMolecularFunction	ubiquitin protein ligase binding	TRAF3 BRCA1 DTX1 OTUB1 SHPRH RFFL	1.56e-03	337	74	6	GO:0031625
GeneOntologyMolecularFunction	guanyl-nucleotide exchange factor activity	EGF KIAA1755 ARHGEF26 PREX2 DENND3	1.67e-03	231	74	5	GO:0005085
GeneOntologyMolecularFunction	ubiquitin-like protein ligase binding	TRAF3 BRCA1 DTX1 OTUB1 SHPRH RFFL	2.12e-03	358	74	6	GO:0044389
GeneOntologyMolecularFunction	extracellular matrix binding	THBS1 SPARC LTBP1	2.52e-03	73	74	3	GO:0050840
GeneOntologyBiologicalProcess	protein polyubiquitination	TRAF3 BRCA1 UBR4 CHFR SHPRH TRIM55 RFFL TRIM68 SYVN1 TRIM3	7.12e-08	289	73	10	GO:0000209
GeneOntologyBiologicalProcess	protein ubiquitination	TRAF3 BRCA1 TRIM4 DTX1 UBR4 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SPRTN SYVN1 TRIM3	1.26e-07	811	73	15	GO:0016567
GeneOntologyBiologicalProcess	post-translational protein modification	PADI4 TRAF3 BRCA1 TRIM4 DTX1 UBR4 OTUB1 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SPRTN SYVN1 TRIM3	1.49e-07	1074	73	17	GO:0043687
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	TRAF3 BRCA1 TRIM4 DTX1 UBR4 OTUB1 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SPRTN SYVN1 TRIM3	3.63e-07	1009	73	16	GO:0070647
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	TRAF3 BRCA1 TRIM4 DTX1 UBR4 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SPRTN SYVN1 TRIM3	4.34e-07	893	73	15	GO:0032446
GeneOntologyBiologicalProcess	sequestering of TGFbeta in extracellular matrix	FBN2 LTBP1	7.38e-05	4	73	2	GO:0035583
GeneOntologyCellularComponent	microfibril	FBN2 LTBP1 FBN3	1.19e-05	13	74	3	GO:0001527
GeneOntologyCellularComponent	external encapsulating structure	THBS1 SPARC FBN2 DST PLXDC2 SPON1 LTBP1 PKHD1L1 MUC5AC FBN3	1.04e-04	658	74	10	GO:0030312
GeneOntologyCellularComponent	BRCA1-A complex	BABAM1 BRCA1	3.41e-04	8	74	2	GO:0070531
GeneOntologyCellularComponent	extracellular matrix	THBS1 SPARC FBN2 DST PLXDC2 SPON1 LTBP1 MUC5AC FBN3	5.01e-04	656	74	9	GO:0031012
GeneOntologyCellularComponent	secretory granule lumen	THBS1 SPARC GLA EGF COMMD9 APAF1	1.03e-03	325	74	6	GO:0034774
GeneOntologyCellularComponent	cytoplasmic vesicle lumen	THBS1 SPARC GLA EGF COMMD9 APAF1	1.11e-03	330	74	6	GO:0060205
GeneOntologyCellularComponent	vesicle lumen	THBS1 SPARC GLA EGF COMMD9 APAF1	1.15e-03	332	74	6	GO:0031983
GeneOntologyCellularComponent	platelet alpha granule lumen	THBS1 SPARC EGF	1.73e-03	67	74	3	GO:0031093
Domain	ZF_RING_1	TRAF3 BRCA1 TRIM4 DTX1 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3	1.09e-10	291	74	13	PS00518
Domain	ZF_RING_2	TRAF3 BRCA1 TRIM4 DTX1 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3	1.47e-10	298	74	13	PS50089
Domain	RING	TRAF3 BRCA1 TRIM4 DTX1 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3	1.95e-10	305	74	13	SM00184
Domain	Znf_RING	TRAF3 BRCA1 TRIM4 DTX1 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3	4.42e-10	326	74	13	IPR001841
Domain	-	TRAF3 BRCA1 TRIM4 DTX1 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3 SP140	2.15e-09	449	74	14	3.30.40.10
Domain	Znf_RING/FYVE/PHD	TRAF3 BRCA1 TRIM4 DTX1 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3 SP140	2.86e-09	459	74	14	IPR013083
Domain	Znf_RING_CS	TRAF3 BRCA1 TRIM4 CHFR SHPRH TRIM55 TRIM54 TRIM68 TRIM3	1.60e-08	163	74	9	IPR017907
Domain	zf-C3HC4	BRCA1 TRIM4 DTX1 MIB1 CHFR TRIM55 TRIM54 TRIM68 SYVN1 TRIM3	1.77e-08	223	74	10	PF00097
Domain	Znf_C3HC4_RING-type	BRCA1 TRIM4 DTX1 TRIM55 TRIM54 TRIM68 SYVN1 TRIM3	3.95e-07	172	74	8	IPR018957
Domain	TB	FBN2 LTBP1 FBN3	2.07e-06	7	74	3	PF00683
Domain	-	FBN2 LTBP1 FBN3	3.30e-06	8	74	3	3.90.290.10
Domain	TB	FBN2 LTBP1 FBN3	4.93e-06	9	74	3	PS51364
Domain	TB_dom	FBN2 LTBP1 FBN3	4.93e-06	9	74	3	IPR017878
Domain	BBOX	TRIM4 TRIM55 TRIM54 TRIM68 TRIM3	7.85e-06	69	74	5	SM00336
Domain	-	TRIM4 TRIM55 TRIM54 TRIM68 TRIM3	9.04e-06	71	74	5	4.10.45.10
Domain	zf-B_box	TRIM4 TRIM55 TRIM54 TRIM68 TRIM3	9.69e-06	72	74	5	PF00643
Domain	ZF_BBOX	TRIM4 TRIM55 TRIM54 TRIM68 TRIM3	1.62e-05	80	74	5	PS50119
Domain	Znf_B-box	TRIM4 TRIM55 TRIM54 TRIM68 TRIM3	1.73e-05	81	74	5	IPR000315
Domain	EGF_CA	THBS1 FBN2 EGF LTBP1 FBN3	2.31e-05	86	74	5	PF07645
Domain	FBN	FBN2 FBN3	4.63e-05	3	74	2	IPR011398
Domain	ANK	POTEB3 POTEE POTEF POTED MIB1 POTEA POTEC	6.09e-05	251	74	7	SM00248
Domain	ANK_REPEAT	POTEB3 POTEE POTEF POTED MIB1 POTEA POTEC	6.40e-05	253	74	7	PS50088
Domain	ANK_REP_REGION	POTEB3 POTEE POTEF POTED MIB1 POTEA POTEC	6.56e-05	254	74	7	PS50297
Domain	Ankyrin_rpt	POTEB3 POTEE POTEF POTED MIB1 POTEA POTEC	7.97e-05	262	74	7	IPR002110
Domain	EGF_CA	THBS1 FBN2 EGF LTBP1 FBN3	1.23e-04	122	74	5	SM00179
Domain	EGF-like_Ca-bd_dom	THBS1 FBN2 EGF LTBP1 FBN3	1.33e-04	124	74	5	IPR001881
Domain	cEGF	FBN2 LTBP1 FBN3	1.45e-04	26	74	3	IPR026823
Domain	cEGF	FBN2 LTBP1 FBN3	1.45e-04	26	74	3	PF12662
Domain	Ank_2	POTEB3 POTEE POTEF MIB1 POTEA POTEC	2.10e-04	215	74	6	PF12796
Domain	Ank	POTEE POTEF POTED MIB1 POTEA POTEC	2.87e-04	228	74	6	PF00023
Domain	zf-CW	MORC1 KDM1B	3.21e-04	7	74	2	PF07496
Domain	Znf_CW	MORC1 KDM1B	3.21e-04	7	74	2	IPR011124
Domain	ZF_CW	MORC1 KDM1B	3.21e-04	7	74	2	PS51050
Domain	Znf-RING_LisH	TRIM55 TRIM54 TRIM3	3.27e-04	34	74	3	IPR027370
Domain	zf-RING_UBOX	TRIM55 TRIM54 TRIM3	3.27e-04	34	74	3	PF13445
Domain	EGF_3	THBS1 FBN2 EGF LTBP1 PGAP6 FBN3	3.38e-04	235	74	6	PS50026
Domain	EGF	THBS1 FBN2 EGF LTBP1 PGAP6 FBN3	3.38e-04	235	74	6	SM00181
Domain	-	POTEB3 POTEE POTEF MIB1 POTEA POTEC	4.50e-04	248	74	6	1.25.40.20
Domain	EGF-like_dom	THBS1 FBN2 EGF LTBP1 PGAP6 FBN3	4.59e-04	249	74	6	IPR000742
Domain	Ankyrin_rpt-contain_dom	POTEB3 POTEE POTEF MIB1 POTEA POTEC	5.10e-04	254	74	6	IPR020683
Domain	EGF_1	THBS1 FBN2 EGF LTBP1 PGAP6 FBN3	5.21e-04	255	74	6	PS00022
Domain	EGF-like_CS	THBS1 FBN2 EGF LTBP1 PGAP6 FBN3	5.88e-04	261	74	6	IPR013032
Domain	EGF_Ca-bd_CS	FBN2 EGF LTBP1 FBN3	5.96e-04	97	74	4	IPR018097
Domain	EGF_2	THBS1 FBN2 EGF LTBP1 PGAP6 FBN3	6.37e-04	265	74	6	PS01186
Domain	EGF_CA	FBN2 EGF LTBP1 FBN3	6.43e-04	99	74	4	PS01187
Domain	ASX_HYDROXYL	FBN2 EGF LTBP1 FBN3	6.68e-04	100	74	4	PS00010
Domain	EGF-type_Asp/Asn_hydroxyl_site	FBN2 EGF LTBP1 FBN3	8.31e-04	106	74	4	IPR000152
Domain	COS_domain	TRIM55 TRIM54	9.96e-04	12	74	2	IPR017903
Domain	COS	TRIM55 TRIM54	9.96e-04	12	74	2	PS51262
Domain	Actin_CS	POTEE POTEF	1.79e-03	16	74	2	IPR004001
Domain	ACTINS_2	POTEE POTEF	2.03e-03	17	74	2	PS00432
Domain	Actin/actin-like_CS	POTEE POTEF	2.27e-03	18	74	2	IPR020902
Domain	ACTINS_ACT_LIKE	POTEE POTEF	2.54e-03	19	74	2	PS01132
Domain	Cupredoxin	PADI4 PKHD1L1	3.40e-03	22	74	2	IPR008972
Domain	Growth_fac_rcpt_	FBN2 EGF LTBP1 FBN3	3.42e-03	156	74	4	IPR009030
Domain	hEGF	FBN2 FBN3	5.48e-03	28	74	2	PF12661
Domain	VWC	THBS1 MUC5AC	5.48e-03	28	74	2	PF00093
Domain	Actin	POTEE POTEF	6.69e-03	31	74	2	IPR004000
Domain	Actin	POTEE POTEF	6.69e-03	31	74	2	PF00022
Domain	ACTIN	POTEE POTEF	6.69e-03	31	74	2	SM00268
Pubmed	A comprehensive framework of E2-RING E3 interactions of the human ubiquitin-proteasome system.	BRCA1 DTX1 MIB1 TRIM54 RFFL TRIM68 SYVN1 TRIM3	2.15e-10	118	76	8	19690564
Pubmed	Five POTE paralogs and their splice variants are expressed in human prostate and encode proteins of different lengths.	POTEB3 POTEE POTED POTEA	7.33e-10	7	76	4	15276201
Pubmed	POTE, a highly homologous gene family located on numerous chromosomes and expressed in prostate, ovary, testis, placenta, and prostate cancer.	POTEB3 POTED POTEA POTEC	1.46e-09	8	76	4	12475935
Pubmed	Duplication and extensive remodeling shaped POTE family genes encoding proteins containing ankyrin repeat and coiled coil domains.	POTEE POTED POTEA	8.34e-07	9	76	3	16364570
Pubmed	A microarray of ubiquitylated proteins for profiling deubiquitylase activity reveals the critical roles of both chain and substrate.	OTUB1 TRIM55 TRIM54 RFFL	1.18e-06	36	76	4	22626734
Pubmed	The Vertebrate Genome Annotation browser 10 years on.	POTEB3 POTEE POTEF BTBD18 POTEA POTEC	1.61e-06	163	76	6	24316575
Pubmed	Epidermal Growth Factor Removal or Tyrphostin AG1478 Treatment Reduces Goblet Cells & Mucus Secretion of Epithelial Cells from Asthmatic Children Using the Air-Liquid Interface Model.	EGF MUC5AC	4.71e-06	2	76	2	26057128
Pubmed	A primate-specific POTE-actin fusion protein plays a role in apoptosis.	POTEE POTEF	4.71e-06	2	76	2	19669888
Pubmed	Regulation of MUC5AC mucin secretion and airway surface liquid metabolism by IL-1beta in human bronchial epithelia.	IL1B MUC5AC	4.71e-06	2	76	2	14527933
Pubmed	Inhibitory effects of ubiquitination of synoviolin by PADI4.	PADI4 SYVN1	4.71e-06	2	76	2	29039504
Pubmed	The role of matricellular proteins thrombospondin-1 and osteonectin during RPE cell migration in proliferative vitreoretinopathy.	THBS1 SPARC	4.71e-06	2	76	2	12658547
Pubmed	Epidermal growth factor and interleukin-1beta utilize divergent signaling pathways to synergistically upregulate cyclooxygenase-2 gene expression in human amnion-derived WISH cells.	EGF IL1B	4.71e-06	2	76	2	15329330
Pubmed	Muscle RING-finger 2 and 3 maintain striated-muscle structure and function.	TRIM55 TRIM54	4.71e-06	2	76	2	27493870
Pubmed	Complex formation of human thrombospondin with osteonectin.	THBS1 SPARC	4.71e-06	2	76	2	3402455
Pubmed	BRCA1 185delAG Mutation Enhances Interleukin-1β Expression in Ovarian Surface Epithelial Cells.	BRCA1 IL1B	4.71e-06	2	76	2	26357657
Pubmed	Comprehensive ubiquitin E2 profiling of ten ubiquitin E3 ligases.	TRIM54 RFFL SYVN1	5.50e-06	16	76	3	23695783
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	FBN2 GLA TRIM4 COMMD9 XPNPEP3 FASTKD1 MIB1 TTC27 HEATR3 TRIM3	5.68e-06	754	76	10	33060197
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	RLF DST BRCA1 ZNF257 MIB1 SHPRH LTBP1 KDM1B MED13	1.16e-05	645	76	9	25281560
Pubmed	Mapping the interactome of HPV E6 and E7 oncoproteins with the ubiquitin-proteasome system.	TRAF3 DTX1 TRIM54 SYVN1 TRIM3	1.35e-05	138	76	5	28786561
Pubmed	Methylation of the APAF-1 and DAPK-1 promoter region correlates with progression of renal cell carcinoma in North Indian population.	SPARC APAF1	1.41e-05	3	76	2	21922274
Pubmed	Role of MERIT40 in stabilization of BRCA1 complex: a protein-protein interaction study.	BABAM1 BRCA1	1.41e-05	3	76	2	24667604
Pubmed	In search of key genes associated with endometriosis using bioinformatics approach.	EGF IL1B	1.41e-05	3	76	2	26366788
Pubmed	Grb2 interacts with SGEF and antagonizes the ability of SGEF to enhance EGF-induced ERK1/2 activation.	EGF ARHGEF26	1.41e-05	3	76	2	24399467
Pubmed	Synthetic lethality between BRCA1 deficiency and poly(ADP-ribose) polymerase inhibition is modulated by processing of endogenous oxidative DNA damage.	BRCA1 OGG1	1.41e-05	3	76	2	31329989
Pubmed	Correlation of BRCA1, TXR1 and TSP1 mRNA expression with treatment outcome to docetaxel-based first-line chemotherapy in patients with advanced/metastatic non-small-cell lung cancer.	THBS1 BRCA1	1.41e-05	3	76	2	21157449
Pubmed	Salivary biomarkers associated with alveolar bone loss.	SPARC IL1B	1.41e-05	3	76	2	17435158
Pubmed	Evolution and expression of chimeric POTE-actin genes in the human genome.	POTEE POTEF	1.41e-05	3	76	2	17101985
Pubmed	Localization of the renal Na-K-Cl cotransporter gene (Slc12a1) on mouse chromosome 2.	THBS1 IL1B	1.41e-05	3	76	2	8589530
Pubmed	Scavenger receptor A impairs interferon response to HBV infection by limiting TRAF3 ubiquitination through recruiting OTUB1.	TRAF3 OTUB1	1.41e-05	3	76	2	31386800
Pubmed	CPEB2-eEF2 interaction impedes HIF-1α RNA translation.	SPARC OTUB1 C2CD2L	1.96e-05	24	76	3	22157746
Pubmed	OTUB1 modulates c-IAP1 stability to regulate signalling pathways.	TRAF3 UBR4 OTUB1	1.96e-05	24	76	3	23524849
Pubmed	A large-scale candidate gene approach identifies SNPs in SOD2 and IL13 as predictive markers of response to preoperative chemoradiation in rectal cancer.	EGF BRCA1 IL1B OGG1	2.27e-05	75	76	4	20644561
Pubmed	The Interaction of OTUB1 and TRAF3 Mediates NLRP3 Inflammasome Activity to Regulate TGF-β1-induced BEAS-2B Cell Injury.	TRAF3 OTUB1	2.82e-05	4	76	2	36976509
Pubmed	Differential expression of gastric MUC5AC in colonic epithelial cells: TFF3-wired IL1 β/Akt crosstalk-induced mucosal immune response against Shigella dysenteriae infection.	IL1B MUC5AC	2.82e-05	4	76	2	22389405
Pubmed	Heparin/heparan sulfate controls fibrillin-1, -2 and -3 self-interactions in microfibril assembly.	FBN2 FBN3	2.82e-05	4	76	2	25034023
Pubmed	RNF126 is a positive regulator of TRAF3 ubiquitination.	TRAF3 OTUB1	2.82e-05	4	76	2	34643674
Pubmed	A locus on 19p13 modifies risk of breast cancer in BRCA1 mutation carriers and is associated with hormone receptor-negative breast cancer in the general population.	BABAM1 BRCA1	2.82e-05	4	76	2	20852631
Pubmed	Overexpression of mucin genes induced by interleukin-1 beta, tumor necrosis factor-alpha, lipopolysaccharide, and neutrophil elastase is inhibited by a retinoic acid receptor alpha antagonist.	IL1B MUC5AC	2.82e-05	4	76	2	12042033
Pubmed	Interleukin-1beta induces MUC2 and MUC5AC synthesis through cyclooxygenase-2 in NCI-H292 cells.	IL1B MUC5AC	2.82e-05	4	76	2	12391274
Pubmed	Secretoneurin induces airway mucus hypersecretion by enhancing the binding of EGF to NRP1.	EGF MUC5AC	2.82e-05	4	76	2	24556756
Pubmed	Loss of BRCA1-A complex function in RAP80 null tumor cells.	BABAM1 BRCA1	2.82e-05	4	76	2	22792303
Pubmed	Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein.	FBN2 LTBP1	2.82e-05	4	76	2	12429738
Pubmed	A study of five human cytokine genes in human essential hypertension.	EGF IL1B	2.82e-05	4	76	2	12009575
Pubmed	Additive effects of EGF and IL-1β regulate tumor cell migration and invasion in gastric adenocarcinoma via activation of ERK1/2.	EGF IL1B	2.82e-05	4	76	2	24789460
Pubmed	Identification of muscle specific ring finger proteins as potential regulators of the titin kinase domain.	TRIM55 TRIM54	2.82e-05	4	76	2	11243782
Pubmed	Three-Dimensional Architecture of the Human BRCA1-A Histone Deubiquitinase Core Complex.	BABAM1 BRCA1	2.82e-05	4	76	2	28009280
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	RLF PPP4R1 BABAM1 UBR4 XPNPEP3 MIB1 PHLPP1 LTBP1 SYVN1 MED13 PREX2 HEATR3	2.94e-05	1327	76	12	32694731
Pubmed	Cul3-KLHL20 E3 ubiquitin ligase plays a key role in the arms race between HIV-1 Nef and host SERINC5 restriction.	UBR4 MIB1 SYVN1	3.16e-05	28	76	3	35474067
Pubmed	Comprehensive proteomic characterization of stem cell-derived extracellular matrices.	THBS1 SPARC FBN2 LTBP1	3.90e-05	86	76	4	28327460
Pubmed	Central corneal thickness does not correlate with TonoLab-measured IOP in several mouse strains with single transgenic mutations of matricellular proteins.	THBS1 SPARC	4.69e-05	5	76	2	23806329
Pubmed	Temporal and spatial immunolocalization of cytokines in murine chronic granulomatous tissue. Implications for their role in tissue development and repair processes.	EGF IL1B	4.69e-05	5	76	2	8231109
Pubmed	MERIT40 Is an Akt Substrate that Promotes Resolution of DNA Damage Induced by Chemotherapy.	BABAM1 BRCA1	4.69e-05	5	76	2	26027929
Pubmed	POGLUT2 and POGLUT3 O-glucosylate multiple EGF repeats in fibrillin-1, -2, and LTBP1 and promote secretion of fibrillin-1.	FBN2 LTBP1	4.69e-05	5	76	2	34411563
Pubmed	Breast cancer-associated Abraxas mutation disrupts nuclear localization and DNA damage response functions.	BABAM1 BRCA1	4.69e-05	5	76	2	22357538
Pubmed	Secreted protein acidic and rich in cysteine (SPARC) gene polymorphism association with hepatocellular carcinoma in Italian patients.	SPARC EGF IL1B	5.22e-05	33	76	3	19817957
Pubmed	O-fucosylation of thrombospondin type 1 repeats is essential for ECM remodeling and signaling during bone development.	SPARC FBN2 SYVN1	6.80e-05	36	76	3	35167946
Pubmed	MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks.	BABAM1 BRCA1	7.03e-05	6	76	2	19261746
Pubmed	Regulation of virus-triggered signaling by OTUB1- and OTUB2-mediated deubiquitination of TRAF3 and TRAF6.	TRAF3 OTUB1	7.03e-05	6	76	2	19996094
Pubmed	The tight-skin (Tsk) mutation is closely linked to B2m on mouse chromosome 2.	THBS1 IL1B	7.03e-05	6	76	2	8111131
Pubmed	Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs.	BABAM1 BRCA1	7.03e-05	6	76	2	26845027
Pubmed	High-throughput mammalian two-hybrid screening for protein-protein interactions using transfected cell arrays.	THBS1 FBN2	7.03e-05	6	76	2	18254948
Pubmed	E3-ligase knock down revealed differential titin degradation by autopagy and the ubiquitin proteasome system.	TRIM55 TRIM54	7.03e-05	6	76	2	34702928
Pubmed	MORC2 regulates DNA damage response through a PARP1-dependent pathway.	MORC1 CHFR	7.03e-05	6	76	2	31616951
Pubmed	Systematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networks.	BRCA1 TRIM4 CHFR TRIM55	8.51e-05	105	76	4	22493164
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	DST BABAM1 BRCA1 UBR4 OTUB1 LTBP1 SPRTN	8.90e-05	481	76	7	28190767
Pubmed	MERIT40 facilitates BRCA1 localization and DNA damage repair.	BABAM1 BRCA1	9.83e-05	7	76	2	19261748
Pubmed	Association of the OGG1 Ser326Cys polymorphism with tooth loss.	IL1B OGG1	9.83e-05	7	76	2	16538639
Pubmed	Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid modulatory element binding protein-1.	TRIM55 TRIM54	9.83e-05	7	76	2	11927605
Pubmed	USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response.	BABAM1 BRCA1	9.83e-05	7	76	2	28569838
Pubmed	Polymorphisms in the transforming growth factor beta 1 pathway in relation to colorectal cancer progression.	THBS1 LTBP1	9.83e-05	7	76	2	19998449
Pubmed	NBA1/MERIT40 and BRE interaction is required for the integrity of two distinct deubiquitinating enzyme BRCC36-containing complexes.	BABAM1 BRCA1	9.83e-05	7	76	2	21282113
Pubmed	Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation.	BABAM1 BRCA1	9.83e-05	7	76	2	31253574
Pubmed	Monoubiquitinylation regulates endosomal localization of Lst2, a negative regulator of EGF receptor signaling.	EGF TRIM3	9.83e-05	7	76	2	19460345
Pubmed	A Large-scale genetic association study of esophageal adenocarcinoma risk.	THBS1 EGF BRCA1 APAF1 IL1B OGG1	1.22e-04	351	76	6	20453000
Pubmed	Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.	BABAM1 BRCA1	1.31e-04	8	76	2	23544013
Pubmed	P311 regulates distal lung development via its interaction with several binding proteins.	SPARC FBN2	1.31e-04	8	76	2	32682987
Pubmed	Analysis of the expression of growth factor, interleukin-1, and lactoferrin genes and the distribution of inflammatory leukocytes in the preimplantation mouse oviduct.	EGF IL1B	1.31e-04	8	76	2	7819439
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DST SPON1 APAF1 PHLPP1 C2CD2L	1.38e-04	225	76	5	12168954
Pubmed	A gene-based risk score for lung cancer susceptibility in smokers and ex-smokers.	BRCA1 IL1B OGG1 MUC5AC	1.47e-04	121	76	4	19789190
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DNAJB11 FBN2 BRCA1 TRIM4 FAM120C BTBD18 TTC27 KDM1B SP140 C2CD2L	1.56e-04	1116	76	10	31753913
Pubmed	Frontline Science: Anthrax lethal toxin-induced, NLRP1-mediated IL-1β release is a neutrophil and PAD4-dependent event.	PADI4 IL1B	1.68e-04	9	76	2	32421904
Pubmed	Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex.	BABAM1 BRCA1	1.68e-04	9	76	2	20656689
Pubmed	Poglut2/3 double knockout in mice results in neonatal lethality with reduced levels of fibrillin in lung tissues.	FBN2 LTBP1	1.68e-04	9	76	2	38844137
Pubmed	Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover.	TRIM55 TRIM54	1.68e-04	9	76	2	21185285
Pubmed	Common variants in immune and DNA repair genes and risk for human papillomavirus persistence and progression to cervical cancer.	BRCA1 IL1B OGG1	1.72e-04	49	76	3	19012493
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	POTEE DST FAM120C UBR4 POTEA FBN3 DNAH14 HEATR3	2.06e-04	736	76	8	29676528
Pubmed	NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control.	BABAM1 BRCA1	2.10e-04	10	76	2	19261749
Pubmed	HSCARG negatively regulates the cellular antiviral RIG-I like receptor signaling pathway by inhibiting TRAF3 ubiquitination via recruiting OTUB1.	TRAF3 OTUB1	2.10e-04	10	76	2	24763515
Pubmed	Platelets Fuel the Inflammasome Activation of Innate Immune Cells.	THBS1 IL1B	2.10e-04	10	76	2	32402278
Pubmed	Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice.	BRCA1 RAD21L1	2.10e-04	10	76	2	35648791
Pubmed	SPARC, a secreted protein associated with cellular proliferation, inhibits cell spreading in vitro and exhibits Ca+2-dependent binding to the extracellular matrix.	THBS1 SPARC	2.56e-04	11	76	2	2745554
Pubmed	K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.	B4GALT7 GLA BABAM1 COMMD9 UBR4 OTUB1 SPRTN	3.57e-04	604	76	7	38803224
Pubmed	BRCA1 tumor suppressor network: focusing on its tail.	BABAM1 BRCA1	3.62e-04	13	76	2	22369660
Pubmed	Direct and indirect control of mitogen-activated protein kinase pathway-associated components, BRAP/IMP E3 ubiquitin ligase and CRAF/RAF1 kinase, by the deubiquitylating enzyme USP15.	BRCA1 OTUB1 TRIM3	3.62e-04	63	76	3	23105109
Pubmed	The first draft of the endostatin interaction network.	THBS1 SPARC	4.22e-04	14	76	2	19542224
Pubmed	Comprehensive screen of genetic variation in DNA repair pathway genes and postmenopausal breast cancer risk.	FANCE BRCA1 OGG1	4.54e-04	68	76	3	20496165
Pubmed	The Fanconi anemia family of genes and its correlation with breast cancer susceptibility and breast cancer features.	FANCE BRCA1	4.86e-04	15	76	2	19536649
Pubmed	Distal airways are protected from goblet cell metaplasia by diminished expression of IL-13 signalling components.	IL1B MUC5AC	4.86e-04	15	76	2	25772331
Pubmed	Identification of a novel actin isoform in hepatocellular carcinoma.	POTEE POTEF	4.86e-04	15	76	2	16824795
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	THBS1 PLXDC2 SPON1 LTBP1	5.03e-04	167	76	4	22159717
Interaction	UBE2D3 interactions	BRCA1 DTX1 OTUB1 MIB1 CHFR TRIM55 TRIM54 RFFL TRIM68 KDM1B SYVN1 IL1B TRIM3	3.65e-11	283	75	13	int:UBE2D3
Interaction	UBE2D2 interactions	BRCA1 DTX1 UBR4 OTUB1 MIB1 CHFR TRIM55 TRIM54 RFFL SYVN1 TRIM3	2.53e-08	318	75	11	int:UBE2D2
Interaction	POTEC interactions	POTEB3 POTEF POTED POTEC	1.23e-07	13	75	4	int:POTEC
Interaction	UBE2D1 interactions	BRCA1 DTX1 OTUB1 MIB1 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM3	1.35e-07	294	75	10	int:UBE2D1
Interaction	POTED interactions	POTEB3 POTED POTEC	1.97e-07	4	75	3	int:POTED
Interaction	BRAP interactions	BRCA1 MIB1 TRIM55 PHLPP1 SPRTN SYVN1	1.54e-06	96	75	6	int:BRAP
Interaction	USP7 interactions	POTEB3 PADI4 TRAF3 FBN2 DST EGF BABAM1 BRCA1 FAM120C CHFR TRIM55 TRIM54 KIAA1755 RFFL SYVN1 POTEC PREX2	4.96e-06	1313	75	17	int:USP7
Interaction	UBE2D4 interactions	DTX1 OTUB1 MIB1 CHFR TRIM54 TRIM3	5.39e-06	119	75	6	int:UBE2D4
Interaction	UBE2N interactions	BRCA1 DTX1 OTUB1 MIB1 CHFR SHPRH TRIM54 RFFL IL1B	6.08e-06	351	75	9	int:UBE2N
Interaction	ATXN3L interactions	TRIM55 TRIM54 RFFL	8.00e-06	11	75	3	int:ATXN3L
Interaction	POTEB3 interactions	POTEB3 POTEF POTED POTEC	8.49e-06	35	75	4	int:POTEB3
Interaction	POTEG interactions	POTEF POTEA POTEC	1.06e-05	12	75	3	int:POTEG
Interaction	UBE2U interactions	DTX1 MIB1 TRIM54 TRIM68 SYVN1 TRIM3	1.32e-05	139	75	6	int:UBE2U
Interaction	OTUB2 interactions	TRAF3 KRT40 TRIM55 TRIM54 RFFL	2.93e-05	96	75	5	int:OTUB2
Interaction	UBE2W interactions	BRCA1 OTUB1 MIB1 CHFR TRIM3	2.93e-05	96	75	5	int:UBE2W
Interaction	GML interactions	POTEF UBR4 FASTKD1 ACAD10	6.45e-05	58	75	4	int:GML
Interaction	FBN2 interactions	THBS1 FBN2 LTBP1 TRIM68	1.01e-04	65	75	4	int:FBN2
Interaction	UBE2E3 interactions	BRCA1 OTUB1 CHFR TRIM55 TRIM54	1.34e-04	132	75	5	int:UBE2E3
Interaction	ZNF667-AS1 interactions	TRIM55 TRIM54	1.36e-04	5	75	2	int:ZNF667-AS1
GeneFamily	Ankyrin repeat domain containing\|POTE ankyrin domain containing	POTEE POTEF POTED POTEA POTEC	2.25e-10	13	53	5	685
GeneFamily	Ring finger proteins	BRCA1 TRIM4 CHFR SHPRH TRIM55 TRIM54 RFFL TRIM68 SYVN1 TRIM3	6.17e-09	275	53	10	58
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM4 TRIM55 TRIM54 TRIM68 TRIM3	8.47e-06	95	53	5	59
GeneFamily	Ankyrin repeat domain containing	POTEE POTEF POTED MIB1 POTEA POTEC	7.33e-05	242	53	6	403
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	BABAM1 BRCA1	1.26e-04	6	53	2	1328
GeneFamily	Zinc fingers CW-type	MORC1 KDM1B	1.75e-04	7	53	2	96
GeneFamily	Ring finger proteins\|Fanconi anemia complementation groups\|Protein phosphatase 1 regulatory subunits\|BRCA1 A complex\|BRCA1 B complex\|BRCA1 C complex	FANCE BRCA1	1.55e-03	20	53	2	548
CoexpressionAtlas	Stromal Cells, Fi.MTS15+.Th, CD45- PDGFRa+ MTS15+, Thymus, avg-3	THBS1 SPARC PLXDC2 SPON1 LTBP1	2.11e-05	97	73	5	GSM777043_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_k-means-cluster#5_top-relative-expression-ranked_1000	RLF THBS1 XPNPEP3 APAF1 MIB1 SHPRH MED13 PREX2	6.48e-05	397	73	8	gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000_k5
CoexpressionAtlas	PP_MEG_top-relative-expression-ranked_2500_k-means-cluster#4	PADI4 THBS1 GLA EGF PLXDC2 POTEF TTC27 LTBP1 SYVN1 PKHD1L1 STRIP2 C2CD2L	6.96e-05	926	73	12	PP_MEG_2500_K4
ToppCell	wk_20-22-Hematologic-Meg-ery-Megakaryocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PADI4 THBS1 EGF LTBP1 PKHD1L1 STRIP2	4.68e-07	170	76	6	eace4dd09cdbde0fa40a6aa0f3dba1114d0ce475
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	THBS1 SPARC DST PLXDC2 SPON1 LTBP1	8.96e-07	190	76	6	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	10x5'v1-week_14-16-Hematopoietic-MK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	THBS1 EGF TTC27 LTBP1 IL1B PKHD1L1	9.24e-07	191	76	6	7edc22e7e70697fb22690699efb352577162709b
ToppCell	Control-Fibroblasts-Intermediate_pathological_FB\|Control / group, cell type (main and fine annotations)	THBS1 SPARC DST PLXDC2 SPON1 LTBP1	1.01e-06	194	76	6	03a269f75a481ea54aea8e6444605db8d6df493d
ToppCell	10x3'2.3-week_14-16-Hematopoietic-MK\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	THBS1 EGF PLXDC2 TTC27 LTBP1 IL1B	1.01e-06	194	76	6	216cba1a04b1a24b080322bc950e7fa2dade5ff1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 SPARC SPON1 KIAA1755 LTBP1 PREX2	1.11e-06	197	76	6	85a8f1d18e0dd1d31341f5131eecd217553bf042
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 SPARC SPON1 KIAA1755 LTBP1 PREX2	1.11e-06	197	76	6	e8e3ba791dfaa0fab35e0329a5e34376f9ee6143
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	THBS1 DST PLXDC2 SPON1 LTBP1 PREX2	1.17e-06	199	76	6	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	THBS1 DST PLXDC2 SPON1 LTBP1 PREX2	1.21e-06	200	76	6	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	THBS1 DST PLXDC2 SPON1 LTBP1 PREX2	1.21e-06	200	76	6	44a68bacdb3d5bf563bd35952176995850933a81
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	THBS1 DST PLXDC2 SPON1 LTBP1 PREX2	1.21e-06	200	76	6	dc61016c61729f69649cfb21f6264e685ce83dea
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	SPARC EGF RAD21L1 LTBP1 PKHD1L1	9.35e-06	165	76	5	6799a6580c667738995cceb31cbf1c7fbdc4ff84
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_0\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPARC EGF RAD21L1 LTBP1 PKHD1L1	9.35e-06	165	76	5	8329d780f244bc31344443b29e5a00529a016662
ToppCell	5'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-Megakaryocyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PADI4 THBS1 EGF LTBP1 PKHD1L1	1.24e-05	175	76	5	b85279b9efd72d7074c4226d50ce139a38c0e1c1
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	POTEE THBS1 SPARC POTEF LTBP1	1.42e-05	180	76	5	fb3d549c2a69b2157a486786ddd775ca16699ed0
ToppCell	Smart-seq2-blood_(Smart-seq2)-hematologic-thrombocytic-platelet\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	POTEE THBS1 SPARC POTEF LTBP1	1.42e-05	180	76	5	beb4d777e0c5fa0a59672dbc3dbb7732498605ff
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST SPON1 KIAA1755 LTBP1 ARHGEF26	1.46e-05	181	76	5	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	control-Others\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	THBS1 SPARC EGF LTBP1 PKHD1L1	1.58e-05	184	76	5	a63b39fcc570b554cf10e8e47c2c1e079034768f
ToppCell	control-Others-Megakaryocytes\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	THBS1 SPARC EGF LTBP1 PKHD1L1	1.58e-05	184	76	5	213915f2889ce8ecbe5f7b19bc2b24ed8c5efe1d
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	DST PLXDC2 SPON1 KIAA1755 LTBP1	1.62e-05	185	76	5	9f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCell	severe-Others\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	THBS1 SPARC EGF LTBP1 PKHD1L1	1.67e-05	186	76	5	234a4bc7c3529daf8804f2a366887d02a47075cd
ToppCell	severe-Others-Megakaryocytes\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	THBS1 SPARC EGF LTBP1 PKHD1L1	1.71e-05	187	76	5	ef16331d1e5abe6bde7f09793c4a87a6ac24e592
ToppCell	droplet-Pancreas-PANCREAS-30m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPARC FBN2 PLXDC2 SPON1 PKHD1L1	1.80e-05	189	76	5	1821ae4a6e37ee4c6308071883f3f447a7c53c53
ToppCell	droplet-Pancreas-PANCREAS-30m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPARC FBN2 PLXDC2 SPON1 PKHD1L1	1.80e-05	189	76	5	1e4d7e8dc98b3d70351e6a6c2aaf9ca01f141b8f
ToppCell	droplet-Pancreas-PANCREAS-30m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPARC FBN2 PLXDC2 SPON1 PKHD1L1	1.80e-05	189	76	5	1dc415ed41815f4296dafd8cf7f3e014c44db1db
ToppCell	megakaryocytic-CD34+_Megakaryoblast\|World / Lineage and Cell class	MORC1 SPARC PLXDC2 TTC27 LTBP1	1.85e-05	190	76	5	1d19b2bd55789bf13e1386332f46c605973d6f8e
ToppCell	PBMC-Severe-cDC_12\|Severe / Compartment, Disease Groups and Clusters	FANCE GLA BRCA1 NCAPH STRIP2	1.85e-05	190	76	5	84ee185939bdefb10705b621a70da27701eadcee
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THBS1 PLXDC2 SPON1 LTBP1 PREX2	1.89e-05	191	76	5	80484d39f34703a33b9bac09826b7a526e883cab
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THBS1 PLXDC2 SPON1 LTBP1 PREX2	1.89e-05	191	76	5	5c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	THBS1 SPARC GLA EGF LTBP1	1.94e-05	192	76	5	5bf420b03c32d7bbc919616bcb7d69f3e3a459ed
ToppCell	droplet-Lung-nan-18m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPARC PLXDC2 SPON1 LTBP1 PREX2	1.94e-05	192	76	5	d22c1135867bcb9076435e2c6eb1cc1248990d0c
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 FBN2 PLXDC2 KIAA1755 LTBP1	1.94e-05	192	76	5	8937a59f6bbe07f671bdabbd3707dc9c17a14cd9
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature4_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	DNAJB11 THBS1 TRAF3 UBR4 PHLPP1	1.94e-05	192	76	5	6bba80887d6f64cf913a5c22f62baaddda417ce0
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 FBN2 PLXDC2 KIAA1755 LTBP1	1.94e-05	192	76	5	e4a7f2673f801b008ca67291db2fb2b9fd2955b8
ToppCell	droplet-Lung-nan-18m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPARC PLXDC2 SPON1 LTBP1 PREX2	1.94e-05	192	76	5	c09966f4d63a739a56db4df7e0e0ee9ecacd21ad
ToppCell	facs-Pancreas-Exocrine-3m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THBS1 FBN2 PLXDC2 KIAA1755 LTBP1	1.94e-05	192	76	5	ac1477433704573f95111eee6263b93668d2845e
ToppCell	PBMC-Severe-Hematopoietic-Platelet-Platelet-plt_0\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	THBS1 SPARC GLA EGF LTBP1	1.94e-05	192	76	5	97975340f9ab3ab6e0aa7751b10e008ff3d21bf2
ToppCell	10x5'v1-week_12-13-Hematopoietic-MK\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	THBS1 EGF PLXDC2 TTC27 LTBP1	2.04e-05	194	76	5	245a3eb6db9c862b73ad34a8cd2898a3688c16f6
ToppCell	COVID-19-Myeloid-TRAM2\|Myeloid / Condition, Lineage and Cell class	THBS1 SPARC SAMD9 DST IL1B	2.04e-05	194	76	5	4060a60c0271e7397b07993a1ef47b3291bba6e3
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST PLXDC2 SPON1 KIAA1755 LTBP1	2.09e-05	195	76	5	f54bc4454270ff06e85596f98199372b50d0179f
ToppCell	ASK428-Epithelial-Transformed_epithelium\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	THBS1 SPARC SAMD9 PLXDC2 PKHD1L1	2.09e-05	195	76	5	c750602c765a51075ba6ede78e3ba80b62374481
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 SPON1 LTBP1 ARHGEF26 PREX2	2.14e-05	196	76	5	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 SPON1 LTBP1 ARHGEF26 PREX2	2.14e-05	196	76	5	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 SPON1 LTBP1 ARHGEF26 PREX2	2.20e-05	197	76	5	09946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	THBS1 SPARC DST SPON1 LTBP1	2.20e-05	197	76	5	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	COVID-19-Fibroblasts\|COVID-19 / group, cell type (main and fine annotations)	THBS1 SPARC DST SPON1 LTBP1	2.20e-05	197	76	5	fb847f2277609c31fffcdf49517243ce0684facf
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SPARC FBN2 PLXDC2 SPON1 LTBP1	2.25e-05	198	76	5	c55608633f66e3d434c5d81324efb07c5120d2c2
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SPARC FBN2 PLXDC2 SPON1 LTBP1	2.25e-05	198	76	5	3e5459038fc6ed95f529eb4d1dc5113e16c19012
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	THBS1 SPARC DST PLXDC2 SPON1	2.25e-05	198	76	5	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	SPARC DST ARHGEF26 DENND3 FBN3	2.30e-05	199	76	5	5a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	THBS1 DST PLXDC2 SPON1 LTBP1	2.30e-05	199	76	5	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	SPARC DST PLXDC2 SPON1 LTBP1	2.36e-05	200	76	5	e663995fc44c340d878d66b278b7b5c2ff784301
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	THBS1 DST PLXDC2 SPON1 LTBP1	2.36e-05	200	76	5	b79628fd1386aa9a3b0e9fa81def0bc100c3c073
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	THBS1 DST PLXDC2 SPON1 LTBP1	2.36e-05	200	76	5	50ca6550998e461ef26dd670351060bd940765a8
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SPARC DST PLXDC2 SPON1 LTBP1	2.36e-05	200	76	5	2cb8a39a12522a9643c6244d5e94cb4559868bb9
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS1 DST PLXDC2 SPON1 LTBP1	2.36e-05	200	76	5	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS1 DST PLXDC2 SPON1 LTBP1	2.36e-05	200	76	5	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPARC PLXDC2 SPON1 LTBP1 PREX2	2.36e-05	200	76	5	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-3\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	SPARC DST PLXDC2 SPON1 LTBP1	2.36e-05	200	76	5	8cc5057b0e5ae9b72ea40d2ffbc52b79bf87ccef
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	THBS1 DST PLXDC2 SPON1 LTBP1	2.36e-05	200	76	5	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Fibroblast\|World / shred by cell class for parenchyma	SPARC DST PLXDC2 SPON1 LTBP1	2.36e-05	200	76	5	dec9ce1bc2571197003596f32e5f742ede72aa79
ToppCell	droplet-Heart-HEART-1m-Hematologic-red_blood_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRCA1 TTC27 TRIM54 RFFL	2.71e-05	101	76	4	6c4524be89cf3eb06769c2963dcded3da1e71ca0
ToppCell	droplet-Marrow-nan-21m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 THBS1 IL1B PKHD1L1	5.15e-05	119	76	4	aa3860c8d25c85baa79a0b6637bce2e269adfcc2
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	B4GALT7 SPARC DST PLXDC2	6.64e-05	127	76	4	353484362448f27e8377447d0c26391b1da7acc5
ToppCell	PND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PADI4 BRCA1 DTX1 IL1B	1.36e-04	153	76	4	489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCell	facs-Brain_Non-Myeloid-Hippocampus_-18m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EGF DTX1 ARHGEF26 MUC5AC	1.40e-04	154	76	4	5ed64bbf603290e6dc34f81d145982690b89dd0d
ToppCell	droplet-Lung-LUNG-1m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 THBS1 IL1B DENND3	1.54e-04	158	76	4	30cceb73cf5e24b692da84d33342fd3b1ad5efe5
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 THBS1 IL1B DENND3	1.54e-04	158	76	4	47793463640f98ee5f680a1ee5786b453355fd57
ToppCell	droplet-Limb_Muscle-nan-24m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PADI4 B4GALT7 IL1B STRIP2	1.62e-04	160	76	4	984990be02642a562f0c60ea99c01f005e7c02c2
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PLXDC2 SPON1 MUC5AC PREX2	1.66e-04	161	76	4	b19f82dd98a3064581793711bb70373f18abecd9
ToppCell	10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3\|Liver / Manually curated celltypes from each tissue	TTC8 SPARC DST DNAH14	1.74e-04	163	76	4	7f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCell	368C-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	PADI4 BRCA1 HEATR3 SP140	1.74e-04	163	76	4	299ac2463b7f58eee419d822a2a2d64b973d87e9
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Mucinous_Colon_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	PPP4R1 PLXDC2 IL1B MUC5AC	1.78e-04	164	76	4	3c15e9b8403b03d67f6ecd7861dc19f1261e3244
ToppCell	mild_COVID-19_(asymptomatic)-B_cell\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	SPARC TTC27 LTBP1 ARHGEF26	1.78e-04	164	76	4	e4d43af7eb04d55328791b554bdf3a7ce6818027
ToppCell	facs-Brain_Non-Myeloid-Cortex_-18m-Epithelial-neuronal_stem_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRCA1 DTX1 SPON1 ACAD10	1.78e-04	164	76	4	0853e75b60b2a78257b660910c3ee15b09c5f5b0
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-MatrixFB-A\|E18.5-samps / Age Group, Lineage, Cell class and subclass	PLXDC2 SPON1 APAF1 PREX2	1.78e-04	164	76	4	519ab4fe885dfe4c50846f346a062acc2cb44299
ToppCell	10x5'v1-week_14-16-Hematopoietic-HSC/MPP_and_pro-HSC/MPP\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	BTBD18 IL1B PREX2 DNAH14	1.91e-04	167	76	4	d041b345014e170e9a45f8c6ef8a37ff56f14750
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	SPARC SAMD9 ARHGEF26 DNAH14	1.95e-04	168	76	4	5e721268f0baa51d3f640f7f4c41db769ebef210
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GLA PLXDC2 IL1B DENND3	2.00e-04	169	76	4	0867528101767fc65e93b3561480bf830c50368d
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 FBN2 SPON1 TTC27	2.00e-04	169	76	4	8f397cf4f9fd7c6fa88d01a95289ce2a6bc6938d
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	THBS1 FBN2 SPON1 TTC27	2.04e-04	170	76	4	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	facs\|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	B4GALT7 SPARC OTUB1 PRR14L	2.09e-04	171	76	4	c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCell	COVID-19-lung-RBC\|lung / Disease (COVID-19 only), tissue and cell type	PADI4 EGF LTBP1 PKHD1L1	2.09e-04	171	76	4	0e8d63c8fbccdda4f1ef00de00667a50464b104b
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage_proliferating_2\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	FANCE LTBP1 NCAPH STRIP2	2.14e-04	172	76	4	e9b97f37bb1732ad9aa89c5e9b513d14022801ac
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRCA1 APAF1 PGAP6 STRIP2	2.14e-04	172	76	4	c5caae0b21e35a2d5dcd898fbfa1ef33f92c019f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPARC DST TRIM54 ARHGEF26	2.14e-04	172	76	4	6c17a1e586a72d1bd80c20c06370429c61dc9f85
ToppCell	facs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BRCA1 APAF1 PGAP6 STRIP2	2.14e-04	172	76	4	48d0cfc37d1b1ae48ed8f8b2711abeb609d2bb6e
ToppCell	facs-Lung-EPCAM-18m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BRCA1 APAF1 PGAP6 STRIP2	2.14e-04	172	76	4	7c085c02b59e24e2a2cd393b5e692f9fb19257fe
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DST SPON1 LTBP1 ARHGEF26	2.28e-04	175	76	4	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	3'-GW_trimst-1-LargeIntestine-Hematopoietic-Myeloid-Megakaryocyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PADI4 THBS1 EGF PKHD1L1	2.28e-04	175	76	4	901f0181a30e5cc609dcada8d8a59f0468df6fa5
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	DNAJB11 SYVN1 PKHD1L1 FBN3	2.28e-04	175	76	4	3b5346fba617292de71963b6175e85a4f182fe30
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 FBN2 SPON1 KDM1B	2.33e-04	176	76	4	33323c97afe509147956b8df9f92ca6b0537e604
ToppCell	(0)_Normal/No_Treatment-(3)_LEPR+_perivascular_cells\|World / Stress and Cell class	SPARC PLXDC2 SPON1 LTBP1	2.33e-04	176	76	4	ce2c32b5ce0da848eb4da35ce4d215cdf74d9113
ToppCell	10x5'-lymph-node_spleen-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|lymph-node_spleen / Manually curated celltypes from each tissue	PADI4 SPARC EGF LTBP1	2.33e-04	176	76	4	50fe3fd862dd6a6550ebb8c27f337cde468efedc
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	DNAJB11 SYVN1 PKHD1L1 FBN3	2.33e-04	176	76	4	dc4e939a07bad21ab36181f9588df3fa662f9a92
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|390C / Donor, Lineage, Cell class and subclass (all cells)	FBN2 SPON1 KIAA1755 LTBP1	2.33e-04	176	76	4	852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_early_1\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	PADI4 SPARC BRCA1 PKHD1L1	2.33e-04	176	76	4	2a15437c5f5dbf6398d5ea70050632c24a7dc66c
ToppCell	390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	FBN2 SPON1 KIAA1755 LTBP1	2.33e-04	176	76	4	d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPP4R1 BRCA1 STRIP2 C2CD2L	2.38e-04	177	76	4	1d5a071157c755f3a27a5c3143015da04ee0b0dc
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	THBS1 SPON1 LTBP1 ARHGEF26	2.38e-04	177	76	4	b872ee91e01265b101b81bd304cf6b95d5419e68
Disease	pancreatic cancer (is_marker_for)	THBS1 EGF APAF1 IL1B MUC5AC	4.63e-06	101	71	5	DOID:1793 (is_marker_for)
Disease	connective tissue disease (implicated_via_orthology)	FBN2 FBN3	1.71e-05	3	71	2	DOID:65 (implicated_via_orthology)
Disease	cholangiocarcinoma (is_implicated_in)	THBS1 OGG1 PREX2	1.99e-05	22	71	3	DOID:4947 (is_implicated_in)
Disease	dry eye syndrome (is_implicated_in)	IL1B MUC5AC	3.41e-05	4	71	2	DOID:10140 (is_implicated_in)
Disease	lung non-small cell carcinoma (is_marker_for)	EGF BRCA1 APAF1 NCAPH PREX2	5.57e-05	169	71	5	DOID:3908 (is_marker_for)
Disease	cervix uteri carcinoma in situ (is_implicated_in)	BRCA1 IL1B	1.19e-04	7	71	2	DOID:8991 (is_implicated_in)
Disease	perinatal necrotizing enterocolitis (implicated_via_orthology)	EGF IL1B	1.19e-04	7	71	2	DOID:8677 (implicated_via_orthology)
Disease	pancreatic cancer (is_implicated_in)	THBS1 BRCA1 IL1B OGG1	1.57e-04	112	71	4	DOID:1793 (is_implicated_in)
Disease	pancreatic ductal carcinoma (is_marker_for)	THBS1 EGF MUC5AC	4.35e-04	61	71	3	DOID:3587 (is_marker_for)
Disease	rhinitis (biomarker_via_orthology)	IL1B MUC5AC	4.38e-04	13	71	2	DOID:4483 (biomarker_via_orthology)
Disease	Parkinson's disease (is_marker_for)	EGF APAF1 OGG1	5.73e-04	67	71	3	DOID:14330 (is_marker_for)
Disease	MYELODYSPLASTIC SYNDROME	FANCE SAMD9 BRCA1	5.73e-04	67	71	3	C3463824
Disease	lupus nephritis (is_marker_for)	EGF OTUB1	7.58e-04	17	71	2	DOID:0080162 (is_marker_for)
Disease	otitis media (biomarker_via_orthology)	IL1B MUC5AC	7.58e-04	17	71	2	DOID:10754 (biomarker_via_orthology)
Disease	Gastric ulcer	EGF IL1B	8.52e-04	18	71	2	C0038358
Disease	Nephritis, Tubulointerstitial	THBS1 GLA	1.16e-03	21	71	2	C0041349
Disease	Reperfusion Injury	THBS1 EGF IL1B	1.31e-03	89	71	3	C0035126
Disease	middle cerebral artery infarction (biomarker_via_orthology)	APAF1 IL1B OGG1	1.48e-03	93	71	3	DOID:3525 (biomarker_via_orthology)
Disease	Nephritis, Interstitial	THBS1 GLA	1.52e-03	24	71	2	C0027707
Disease	Fanconi Anemia	FANCE BRCA1	1.65e-03	25	71	2	C0015625
Disease	Acute monocytic leukemia	FANCE BRCA1	1.79e-03	26	71	2	C0023465
Disease	Hodgkins lymphoma, multiple myeloma, non-Hodgkins lymphoma	PHLPP1 SP140	2.07e-03	28	71	2	EFO_0000183, EFO_0001378, EFO_0005952
Disease	urinary bladder cancer (is_marker_for)	THBS1 SPARC IL1B	2.22e-03	107	71	3	DOID:11054 (is_marker_for)
Disease	Miller Dieker syndrome	FANCE BRCA1	2.22e-03	29	71	2	C0265219
Disease	cervical cancer (is_implicated_in)	BRCA1 IL1B	2.38e-03	30	71	2	DOID:4362 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
EDPQEDMEVIVKCCS	APAF1	791	O14727
KTDMLCTDKEEECPA	BCORP1	71	Q8N888
DVIVESCMEGICKPD	ACAD10	176	Q6JQN1
CQEEPDSCISEKLFM	GLA	56	P06280
PMECAKEITCQATID	ARHGEF26	841	Q96DR7
DQTLCMDIDECDRQP	FBN3	1841	Q75N90
PLEDCSEINCMIRVK	DENND3	1116	A2RUS2
DNSECICVPENEKMN	RAD21L1	251	Q9H4I0
ALSCELEQCPEQMNK	MORC1	846	Q86VD1
KCKLTICPEEENMDD	PADI4	331	Q9UM07
IKAVQCQEDECALML	POTEF	211	A5A3E0
QMKCSFQDLDLCPLD	IL1B	31	P01584
IQEQCEQDIPMVCPD	KRT40	121	Q6A162
PQEEQSVCIMIKCLS	KIAA1755	111	Q5JYT7
ERQNMCKDLIDPCTS	DST	1701	Q03001
PCTVLNIMLDCDKTA	B4GALT7	306	Q9UBV7
VKLQCFDMDECQDPS	LTBP1	1461	Q14766
IFDEDKMQCVATCPT	MUC5AC	1216	P98088
LQLMCPENAEDCEQA	PGAP6	471	Q9HCN3
ADCICLMALDKPQAV	OGG1	251	O15527
QKVKNPPDEDCTICM	DTX1	401	Q86Y01
DIKEQTMCPVCLDRL	MIB1	956	Q86YT6
IKAVQCQEDECVLML	POTEB3	211	A0JP26
IKAVQCQEDECALML	POTEE	211	Q6S8J3
KEFCQQEVEPMCKES	OTUB1	201	Q96FW1
NAMQKILECPICLEL	BRCA1	16	P38398
LCQDSPMCTKLQDIL	BTBD18	416	B2RXH4
TCLLQMKIQEDPSLC	COMMD9	146	Q9P000
DKMEETLTCIICQDL	CHFR	296	Q96EP1
ALEIIVNMCCNEDPS	HEATR3	366	Q7Z4Q2
NECGKALCVRPDVME	KDM1B	276	Q8NB78
CPEKVIICLDLSEEM	BABAM1	91	Q9NWV8
EELCCVAELDNPMQQ	C2CD2L	306	O14523
KLCSDIDECEMGVPV	EGF	866	P01133
MAEPDLECEQIRLKC	CDK10	1	Q15131
GEIKIPVCIEDECNM	FAM120C	631	Q9NX05
CEPLIIQMNKCTDEE	FASTKD1	36	Q53R41
CDPDQMKFTQCLAEL	AGBL2	666	Q5U5Z8
QMTQEVVCDECPNVK	DNAJB11	186	Q9UBS4
EQKILEDSLPLEMCC	DNAH14	3411	Q0VDD8
CCLVKMESLEPDAQV	FANCE	421	Q9HB96
DGRDIDECKVMPNLC	FBN2	2446	P35556
CENVKDCTVLPEMKE	PRR14L	1271	Q5THK1
LIKAVQCQEDECALM	POTEA	136	Q6S8J7
IKAVQCQEDECVLML	POTEC	211	B2RU33
IKAIQCQEDECVLML	POTED	211	Q86YR6
PEELQAMDNVCIICR	SYVN1	281	Q86TM6
NEDLEQVEKCMLPEC	SPON1	651	Q9HCB6
QVEKCMLPECPIDCE	SPON1	656	Q9HCB6
FVCQTVIEDDCLPMD	PPP4R1	846	Q8TF05
DVQIKNEEELEKCPM	STRIP2	476	Q9ULQ0
LEENLCKICMDSPID	RFFL	311	Q8WZ73
EDIMTALEIICENEC	SAMD9	646	Q5K651
CPEESKEKMCENTEP	PLXDC2	371	Q6UX71
ICLDEAQMVECPTVK	SHPRH	816	Q149N8
PISCCLKEMSEEKQE	MED13	241	Q9UHV7
CVEMTDLKAPLQQCA	NCAPH	296	Q15003
SMDNLEKQLICPICL	TRIM54	16	Q9BYV2
MIALQKHEDTDCPCV	TRAF3	186	Q13114
CEKMENAELDVPIQS	THBS1	171	P07996
TMDNLEKQLICPICL	TRIM55	16	Q9BYV6
EDVLIMCEACSQSPE	TRIM68	111	Q6AZZ1
QLCADLCTQMLEKSP	TTC8	21	Q8TAM2
ISQKDCDCLHVVEPM	TMEM9B	61	Q9NQ34
TCLCSMLPNEDAIKE	RLF	256	Q13129
KVCELDENNTPMCVC	SPARC	81	P09486
ALKEVEMCVCQIDDL	PREX2	1036	Q70Z35
KVNPSDCVDMVCDAK	PKHD1L1	3666	Q86WI1
SKMVNCPVCQNEVLE	SPRTN	451	Q9H040
DCPKEMNDIEQICSQ	XPNPEP3	491	Q9NQH7
VMQLPEIKCVDLSCN	PHLPP1	1101	O60346
LERQMCPEEQLKCEF	SP140	751	Q13342
MEAEDIQEELTCPIC	TRIM4	1	Q9C037
IKLADCEQFQMPDLC	TTC27	326	Q6P3X3
CEQFQMPDLCAEEIA	TTC27	331	Q6P3X3
QMEELIEEPGLTCCI	UBR4	4826	Q5T4S7
EVQPMDKQFLVCSIC	TRIM3	11	O75382
DLITCLEQGKEPCNM	ZNF257	51	Q9Y2Q1